RESUMO O objetivo da pesquisa foi avaliar a secagem da polpa de trapiá com a adição de aditivos de secagem, determinando a cinética de secagem e as propriedades termodinâmicas das amostras. Foram elaboradas formulações a partir da polpa e os aditivos monoglicerídeos, carboximetilcelulose - CMC e goma guar em diferentes combinações e concentrações (F1 - 0,5% de CMC e 0,5% de Monoglicerídeos; F2 - 0,5% de Goma Guar e 0,5% de Monoglicerídeos; e F3 - 0,25% de Goma Guar, 0,5% de CMC e 0,5% de Monoglicerídeos). A secagem foi realizada a 50, 60 e 70 ºC com camadas de 0,5 cm de espessura. A cinética de secagem foi determinada e diferentes modelos matemáticos foram ajustados aos dados. O modelo Midilli foi o que melhor representou a cinética de secagem, com coeficientes de determinação ≥ 0,9985. As difusividades efetivas aumentaram com o aumento da temperatura, com magnitudes da ordem de 10-10 m2 s-1. As variações de entalpia (ΔH) diminuíram com o aumento da temperatura e foram positivas. As variações de entropia (ΔS) foram negativas e inversamente proporcionais à temperatura. A variação da energia livre de Gibbs (ΔG) foi positiva e aumentou com o aumento da temperatura. amostras monoglicerídeos F1 F (F 05 0 5 Monoglicerídeos 025 25 0,25 Monoglicerídeos. . Monoglicerídeos) 50 6 7 0, espessura dados 09985 9985 0,9985 1010 10 10-1 m s1. s1 s 1. 1 s-1 ΔH (ΔH positivas ΔS (ΔS ΔG (ΔG 02 2 0,2 0998 998 0,998 101 10- s- 099 99 0,99 09 9 0,9

ABSTRACT The objective of the research was to study the drying of trapiá pulp with the addition of drying aids, determining the drying kinetics and thermodynamic properties of the samples. Formulations of the pulp was treated with the additives monoglycerides, carboxymethylcellulose - CMC and guar gum in different combinations and concentrations (F1 - 0.5% CMC and 0.5% Monoglycerides; F2 - 0.5% Guar Gum and 0.5% Monoglycerides; and F3 - 0.25% Guar Gum, 0.5% CMC and 0.5% Monoglycerides) trapiá. Drying was carried out at 50, 60 and 70 ºC with 0.5 cm thick layers. The drying kinetics were determined, and different mathematical models fitted to the data. The Midilli model best represented the drying kinetics, with determination coefficients ≥ 0.9985. The effective diffusivities increased with increase in temperature with magnitudes to the order of 10-10 m2 s-1. The enthalpy variations (ΔH) reduced with increase in temperature and were positive. The entropy variations (ΔS) were negative and inversely proportional to the temperature. The variation in Gibbs free energy (ΔG) was positive and increased with increase in temperature. aids samples monoglycerides F1 F (F 05 0 5 Monoglycerides 025 25 0.25 50 6 7 0. layers determined data 09985 9985 0.9985 1010 10 10-1 m s1. s1 s 1. 1 s-1 ΔH (ΔH ΔS (ΔS ΔG (ΔG 02 2 0.2 0998 998 0.998 101 10- s- 099 99 0.99 09 9 0.9

RESUMO O uso de Bacillus sp. atenua o estresse salino e aumenta o rendimento produtivo em plantas de soja. Neste contexto, o objetivo do presente estudo foi avaliar a produção da soja cultivada sob diferentes formas de adubação e estresse salino, inoculada com Bacillus sp. O experimento foi realizado na área experimental da Universidade da Integração Internacional da Lusofonia Afro-Brasileira (UNILAB), Redenção, Ceará. Utilizou-se um delineamento inteiramente casualizado em esquema fatorial 4 x 2 x 2, com cinco repetições, correspondente a quatro formas de adubação (F1 = 100% da recomendação de NPK; F2 = 50% da recomendação de NPK; F3 = 100% de biofertilizante bovino; F4 = organomineral - 50% de NPK + 50% de biofertilizante bovino), duas condutividades elétricas da água de irrigação (CEa - 0,3 e 4,0 dS m-1), com e sem inoculação de Bacillus sp. As formas de adubação orgânica com 100% da recomendação através de biofertilizante bovino, adubação organomineral - 50% mineral e 50% orgânica com biofertilizante bovino e 50% da recomendação de NPK, proporcionam maior desempenho produtivo da cultura soja irrigada com água de menor salinidade. A adubação organomineral - 50% mineral e 50% orgânica com biofertilizante bovino, foi mais eficiente para produção da cultura da soja, na ausência ou presença de Bacillus sp. O estresse salino afetou negativamente os componentes de produção da cultura da soja em todas as formas de adubação. sp contexto AfroBrasileira Afro Brasileira UNILAB, UNILAB , (UNILAB) Redenção Ceará Utilizouse Utilizou se repetições F1 F (F 100 50 bovino) CEa 03 0 3 0, 40 4, m1, m1 m 1 m-1) salinidade (UNILAB 10 5 m-1 m-

ABSTRACT The use of Bacillus sp. mitigates salt stress and increases the productive yield in soybean plants. In this context, the objective of the present study was to evaluate the production of soybean grown under different forms of fertilization and salt stress, inoculated with Bacillus sp. The experiment was performed in the experimental area of the University of International Integration of Afro-Brazilian Lusophony (UNILAB), Redenção, Ceará, Brazil. A completely randomized design was used in a 4 x 2 x 2 factorial scheme, with five replications, corresponding to four forms of fertilization (F1 = 100% of the NPK recommendation; F2 = 50% of the NPK recommendation; F3 = 100% bovine biofertilizer; F4 = organomineral fertilization - 50% NPK + 50% bovine biofertilizer), two electrical conductivities of the irrigation water (ECw - 0.3 and 4.0 dS m-1), with and without inoculation of Bacillus sp. The forms of fertilization organic with 100% of the recommendation through bovine biofertilizer, organomineral fertilization - 50% mineral and 50% organic with bovine biofertilizer, and 50% of the NPK recommendation promote greater productive performance of the soybean crop irrigated with water of lower salinity. Organomineral fertilization - 50% mineral and 50% organic with bovine biofertilizer was more efficient for soybean production, in the absence or presence of Bacillus sp. Salt stress negatively affected the production components of soybean crop under all forms of fertilization. sp plants context AfroBrazilian Afro Brazilian UNILAB, UNILAB , (UNILAB) Redenção Ceará Brazil scheme replications F1 F (F 100 50 biofertilizer) ECw 03 0 3 0. 40 4. m1, m1 m 1 m-1) salinity (UNILAB 10 5 m-1 m-

BACKGROUND Culex quinquefasciatus, a cosmopolitan, domestic, and highly anthropophilic mosquito, is a vector of pathogenic arboviruses such as West Nile virus and Rift Valley virus, as well as lymphatic filariasis. The current knowledge on its reproductive physiology regarding vitellogenin expression in different tissues is still limited. OBJECTIVES In this study, we analysed the transcriptional profiles of vitellogenin genes in the fat body and ovaries of C. quinquefasciatus females during the first gonotrophic cycle. METHODS C. quinquefasciatus ovaries and/or fat bodies were dissected in different times during the first gonotrophic cycle and total RNA was extracted and used for reverse transcription polymerase chain reaction, quantitative real time-PCR, and in situ hybridisation. FINDINGS We confirmed the classical descriptions of the vitellogenic process in mosquitoes by verifying that vitellogenin genes are transcribed in the fat bodies of C. quinquefasciatus females. Using RNA in situ hybridisation approach, we showed that vitellogenin genes are also transcribed in developing ovaries, specifically by the follicle cells. MAIN CONCLUSIONS This is the first time that vitellogenin transcripts are observed in mosquito ovaries. Studies to determine if Vg transcripts are translated into proteins and their contribution to the reproductive success of the mosquito need to be further investigated. cosmopolitan domestic filariasis limited study C andor or reaction timePCR, timePCR PCR, PCR time-PCR approach cells investigated

Resumo Objetivo analisar o risco de queda e sua associação com as variáveis demográficas, clínicas, estado cognitivo, risco de sarcopenia e fragilidade da pessoa idosa hospitalizada em uma clínica médica de um hospital universitário. Método Estudo quantitativo, observacional, transversal e analítico realizado com 60 pessoas idosas hospitalizadas na clínica médica de um hospital universitário da cidade de São Paulo – SP, Brasil, com o uso dos seguintes questionários: perfil demográfico, dados clínicos, Mini Exame do Estado Mental, Escala de Morse, Escala SARC-F e Índice de Fragilidade Tilburg. Foram realizadas análises descritivas e teste de normalidade de Kolmogorov-Smirnov. Para as variáveis quantitativas foi utilizado o teste de correlação de Spearman e para categóricas, o teste U Mann-Whitney. Para identificar a associação, foi utilizada a regressão linear múltipla e adotado um nível de significância de 5%. Resultados Predomínio do sexo feminino, entre 60-79 anos e sem companheiro (a). Ademais, 80% apresentavam comprometimento cognitivo, 88,3% foram categorizados como frágeis, 60% apresentavam risco para sarcopenia e 75% possuíam alto risco de queda durante a hospitalização. Verificou-se associação do comprometimento cognitivo, ser frágil e ter risco de sarcopenia com o risco de queda na pessoa idosa hospitalizada. Conclusão o elevado risco de quedas em idosos hospitalizados está diretamente relacionado com a presença de deficit cognitivo, síndrome da fragilidade e o risco para sarcopenia, afirmando que esses fatores merecem atenção dos gestores e profissionais de enfermagem. demográficas clínicas cognitivo quantitativo observacional 6 SP Brasil questionários demográfico clínicos Mental Morse SARCF SARC F Tilburg KolmogorovSmirnov. KolmogorovSmirnov Kolmogorov Smirnov. Smirnov Kolmogorov-Smirnov categóricas MannWhitney. MannWhitney Mann Whitney. Whitney Mann-Whitney 5 5% feminino 6079 79 60-7 a. . (a) Ademais 80 883 88 3 88,3 frágeis 75 hospitalização Verificouse Verificou se enfermagem 607 7 60- (a 8 88,

Abstract Objective To analyze the risk of falls and its association with demographic and clinical variables, cognitive status, risk of sarcopenia and frailty among older adults hospitalized in a medical clinic of a university hospital. Method A quantitative, observational, cross-sectional analytical study of 60 older adults hospitalized in the medical clinic of a university hospital in São Paulo city, São Paulo state, Brazil, was carried out. Questionnaires collecting demographic profile and clinical data, the Mini-Mental State Examination, Morse Scale, SARC-F Scale and Tilburg Frailty Indicator were applied. Descriptive analyses and the Kolmogorov-Smirnov normality test were performed. Spearman’s correlation test was used for quantitative variables and the Mann-Whitney U-test for categorical variables. Multiple linear regression was used to identify the associations and a significance level of 5% was adopted. Results The study sample comprised predominantly individuals that were female, aged 60-79 years and without a partner. Overall, 80% had cognitive impairment, 88.3% were diagnosed as frail, 60% were at risk for sarcopenia, and 75% had a high risk of falls during hospitalization. Cognitive impairment, frailty and sarcopenia risk were associated with risk of falls in the hospitalized older adults. Conclusion High risk of falls in the hospitalized older adults was directly associated with the presence of cognitive impairment, frailty syndrome and sarcopenia risk, confirming that these factors warrant attention from managers and nursing professionals. status observational crosssectional cross sectional 6 city state Brazil out data MiniMental Mini Mental Examination SARCF SARC F applied KolmogorovSmirnov Kolmogorov Smirnov performed Spearmans Spearman s MannWhitney Mann Whitney Utest U 5 adopted female 6079 79 60-7 partner Overall 80 impairment 883 88 3 88.3 frail 75 hospitalization professionals 607 7 60- 8 88.

This study searched for a new pre-formulation based on the natural compound from the class of the avermectins, named abamectin (ABA), in order to improve its action against Aedes aegypti larvae by complexation with β-cyclodextrin (βCD). Concerning the low aqueous solubility of ABA, even in the presence of βCD, it was also invoked the strategy of working with hydrophobic nanoprecipitates (HNPs). For these purposes, molecular and supramolecular characterizations of 1:1 ABA/βCD complex and evaluation of its toxicity against A. aegypti larvae were performed. In the physical-chemistry characterizations, changes in the infrared spectra and thermal profiles in relation to precursors confirmed the occurrence of interactions between ABA and βCD in solid state. Nuclear magnetic resonance (NMR) data suggest the inclusion of ABA in βCD via benzofuran ring. Isothermal titration calorimetry (ITC) experiments allowed to verify the formation of complex with a 1:1 stoichiometry, which was entropy driven. The dynamic light scattering and zeta potential data from inclusion compounds demonstrated changes in the size of the ABA/βCD HNP if compared with the ABA HNP. Finally, the results for biological assays demonstrate that the strategy to prepare the inclusion compound led to an increase in the larvicidal activity in relation to free ABA.

Abstract This study analyzed the genetic diversity in Coffea canephora genotypes by univariate and multivariate statistical analysis, based on concentrations of macro- and micronu trients in coffee leaves in the stages of pre-flowering and grain filling. The experiment was arranged in randomized blocks with three replications, in a 42x2 factorial design, in which factor one represented the evaluated genotypes and factor two the periods of leaf sampling, i.e., pre-flowering and grain filling. The data of leaf nutrient concentrations were subjected to analysis of variance by the F test (p <0.01), and genetic parameters were estimated. For the study of genetic diversity, the genotypes were grouped by the hierarchical unweighted pair-group method using arithmetic averages (UPGMA). The relative importance of a trait to predict genetic diversity was also studied. There is genetic divergence for leaf nutrient concentration in C. canephora genotypes. With a maximum limit of 60% of dissimilarity between genotypes, four groups were also formed by UPGMA. For the 42 evaluated geno types, leaf S concentration was the most important trait for genetic diversity; this genotypic variability should be investigated to enhance the efficiency of nutritional diagnosis.

Resumen Este estudio analizó la diversidad genética en los genotipos de Coffea canephora mediante análisis estadístico univariado y multivariado, basado en las concentraciones de macro y micronutrientes en las hojas de café en las etapas de pre-floración y llenado de granos. El experimento se organizó en bloques aleatorios con tres repeticiones, en un diseño factorial de 42x2, donde el factor uno representaba los genotipos evaluados y el factor dos los períodos de muestreo de hojas, es decir, pre-floración y llenado de granos. Los datos de las concentraciones nutricionales de las hojas se sometieron a un análisis de varianza mediante la prueba F (p <0,01), y se estimaron los parámetros genéticos. Para el estudio de la diversidad genética, los genotipos se agruparon por el método jerárquico de pares de grupos no ponderados, utilizando medios aritméticos (UPGMA). También se ha estudiado la importancia relativa de un rasgo para predecir la diversidad genética. Existe divergencia genética para la concentración de nutrientes en las hojas en los genotipos de C. canephora. Con un límite máximo del 60% de disimilitud entre los genotipos, el método UPGMA formó cuatro grupos. Para los 42 genotipos evaluados, la concentración de S en las hojas fue la característica más importante para la diversidad genética. La variabilidad genotípica debe investigarse para mejorar la eficiencia del diagnóstico nutricional.

Abstract Aim: The aim was to compare performance in specific-skill tests and motor coordination between groups with different technical efficiency and verify possible variables related to specific skills and motor coordination that contribute to discriminate players into high- and low-technical efficiency. Methods: The sample consisted of 82 young soccer players (12-15 years). Body size, bone age, motor performance tests, soccer-specific skill tests, and frequency of technical actions in SSG were analyzed. Statistic cluster-derived ANOVA F was used to identify which variables related to technical action most contributed to classifying subjects with similar performance. Discriminant analysis (Stepwise Method) was used to verify which predictor variables discriminated players into groups of low- and high-frequency technical actions in SSG. Statistical significance was set at 5%. Results: The group of high technical efficiency presented better performance in motor tests, shuttle run (P = 0.04; ES = −0.55), jumping laterally (P = 0.02; ES = 0.58), kicking speed (P = 0.03; ES = 0.60), soccer-specific skill tests, leading the ball in a straight line (LBSL) (P = 0.01; ES = −0.75), and zig-zag ball control (ZZBC) (P = 0.04; ES = −0.55); variable leading the ball in a straight line correctly discriminated 60% of players into high- and low-frequency groups. Conclusion: The frequency of technical actions in SSG was poorly influenced by motor performance and specific skill tests, and only the LBSL test correctly classified players of different frequencies of technical actions in SSG.

Abstract Fifty-five watermelon accessions were inoculated in pots using Fusarium oxysporum f. sp. niveum chlamydospores in a completely randomized design with five replications. Among the 42 accessions that were resistant, twelve accessions with a mean score ≤1 were selected for morpho-agronomic characterization. ‘Sugar Baby’ and ‘Charleston Gray’ were used as controls. Field research was conducted over two production cycles in a randomized block design with three replications and five plants per plot. For the characterization 13 quantitative agronomic traits were used. The dissimilarity measures were obtained by the sum of the matrices of standardized mean Euclidean distance. Coefficients of variation ranged from 5.33% (number of days until 50% of plants with at least one female flower) and 17.20% (mass of characterized fruit). In the second cycle, a reduction in days was observed for the flowering. For soluble solids content, the accession BGH-UNIVASF 40 was statistically equal to the commercial cultivars in the second cycle. Accessions were grouped similarly using two grouping methods, Tocher and the farthest neighbor method. The most promising accessions were BGH-UNIVASF 40, 169, 177 and 210 for use in future hybridizations. BGH-UNIVASF 76, 128 and 185 (Citrullus lanatus var. citroides) can be used as resistant Fusarium wilt rootstocks.

Resumo O objetivo neste estudo foi avaliar a influência do pré-aquecimento, conteúdo de carga e espessura da cerâmica na espessura da película, resistência de união ao microcisalhamento, grau de conversão e alteração de cor na cimentação de cerâmicas. Dois compósitos experimentais foram preparados (Bis-GMA / UDMA / BisEMA / TEGDMA), com diferentes quantidades de carga (65% ou 50% em peso), simulando um compósito convencional e um fluido. O fluido (F) foi usado à temperatura ambiente e o convencional, à temperatura ambiente (C) ou pré-aquecido (CPH). Foram preparados discos de cerâmica com diferentes espessuras (0,4mm, 0,8mm, 1,5mm). A espessura da película foi avaliada de acordo com a ISO 4049 (n=10). A resistência de união ao microcisalhamento (n=10) foi avaliada em esmalte utilizando espécimes fotopolimerizados através da cerâmica. O grau de conversão foi avaliado usando espectroscopia Raman. A alteração de cor das restaurações cerâmicas (n=10) foi avaliada por espectrofotometria. Os resultados foram submetidos à ANOVA 2- fatores e ao teste post hoc de Tukey (a=5%). Para espessura de película foi utilizada a ANOVA 1-fator (a=5%). O grupo C apresentou maior espessura de película; o CPH produziu uma espessura semelhante ao F. Todos os compósitos mostraram resistência de união ao microcisalhamento similares. O grau de conversão do F foi maior que C e CPH. O grau de conversão dos compósitos fotoativados através 0,4 mm foi maior que dos compósitos fotoativados através de cerâmicas mais espessas. O grupo C apresentou a maior mudança de cor, enquanto o CPH apresentou mudança de cor semelhante ao F. Em conclusão, compósitos convencionais pré-aquecidos assim como compósitos fluídos, parecem ser uma alternativa em potencial para cimentar laminados cerâmicos.

Abstract The aim of this study was to evaluate of pre-heating, filler contents and ceramic thickness on film thickness, microshear bond strength, degree of conversion and color change on ceramic veneers. Two experimental composites were prepared (Bis-GMA/UDMA/BisEMA/ TEGDMA), with different amounts of filler (65% or 50%wt) simulating a conventional and a flowable composite. The flowable (F) was used at room temperature and, the conventional either at room temperature (C) or pre-heated (CPH). Disk-shaped ceramics with different thickness (0.4 mm, 0.8 mm, 1.5 mm) were prepared. The film thickness was evaluated according to the ISO 4049 (n=10). The microshear bond strength (n=10) was evaluated in enamel using tubing specimens light-cured through the ceramic veneer. The degree of conversion was evaluated using Raman spectroscopy. The color change of the ceramic restorations (n=10) was evaluated by spectrophotometry. The results were submitted to 2-way ANOVA and Tukey’s post hoc test (a=5%). For the film thickness 1-way ANOVA was used (a=5%). The C presented the thicker film thickness; the CPH produced a similar film thickness in comparison to the F. All composites showed similar microshear bond strength. The degree of conversion of the F was higher than the C and CPH. The degree of conversion of the composites photo-activated through a 0.4 mm was higher than the composites photo-activated through thicker ceramics. The C showed the highest color change, while the CPH showed similar color change to the F. In conclusion, pre-heated conventional composites seem to be a potential alternative to lute ceramic veneers such as the flowable composites.

RESUMO OBJETIVO O diabetes é importante causa de mortalidade cardiovascular. Nos últimos anos, a mortalidade diminuiu substancialmente, mais em diabéticos do que em não diabéticos, em grande parte devido ao controle de outros fatores de risco cardiovasculares. Nosso estudo tem como objetivo analisar o controle de dislipidemia em duas coortes de diabéticos. MÉTODOS Foram estudados pacientes de duas coortes distintas, sendo 173 pacientes do BHS (Brasília Heart Study) e 222 pacientes do BDS (Brazilian Diabetes Study). Os dados sobre controle de dislipidemia foram estudados nas duas populações diferentes. Todos os pacientes eram diabéticos. RESULTADOS Há diferenças significativas em relação às comorbidades entre os grupos de LDL-C no BDS. A média de hemoglobina glicada é de 8,2 no grupo com LDL-C > 100, comparado com 7,7 e 7,5 nos grupos 70-100 e < 70, respectivamente (p = 0,024). Há maior porcentagem de pacientes hipertensos com LDL entre 70-100 (63,9%), quando comparado aos grupos < 70 e > 100 (54,3% e 54,9%, respectivamente; p = 0,005). A pressão diastólica é mais elevada no grupo com LDL > 100, com média de 87 mmHg, comparado com 82,6 mmHg e 81,9 mmHg nos grupos 70-100 e < 70, respectivamente (p = 0,019). O grupo com LDL > 100 tem maior porcentagem de tabagistas (8,7%) quando comparado aos grupos com LDL entre 70-100 e < 70 (5,6% e 4,3%, respectivamente; p = 0,015). Há, também, diferença na incidência prévia de coronariopatia. No grupo com LDL < 70, 28,3% dos pacientes já apresentaram infarto prévio, comparados com 11,1% e 10,6% nos grupos 70-100 e > 100, respectivamente (p < 0,001). CONCLUSÃO Os dados do nosso estudo mostram que o controle de dislipidemia em diabéticos é inadequado, e há uma tendência de associação direta entre descontrole glicêmico e descontrole de dislipidemia, além de associação com outros fatores de risco cardiovascular, como hipertensão diastólica e tabagismo. Esse pior controle pode estar relacionado ao platô no descenso da curva de mortalidade, e o investimento nesse quesito pode melhorar a saúde cardiovascular dos diabéticos.

SUMMARY OBJECTIVE Diabetes is one of the leading causes of cardiovascular mortality. Over the last years, mortality has decreased significantly, more in individuals with diabetes than in healthy ones. That is mostly due to the control of other cardiovascular risk factors. The objective of our study was to analyze the dyslipidemia control in two diabetes cohorts. METHODS Patients from two distinct cohorts were studied, 173 patients from the BHS (Brasília Heart Study) and 222 patients from the BDS (Brazilian Diabetes Study). The data on dyslipidemia control were studied in both different populations. All patients had diabetes. RESULTS There are significant differences concerning comorbidities between the LDL-C and BDS groups. The average glycated hemoglobin is of 8.2 in the LDL-C > 100 group in comparison with 7.7 and 7.5 in the 70-100 and < 70 groups, respectively (p = 0.024). There is a higher percentage of hypertensive patients with LDL between 70-100 (63.9%), when comparing the < 70 and > 100 groups (54.3% and 54.9%, respectively; p = 0.005). Diastolic pressure is higher in the group with LDL > 100, with an average of 87 mmHg, in comparison with 82.6 mmHg and 81.9 mmHg in the 70-100 and < 70 groups, respectively (p = 0.019). The group with LDL > 100 has the greatest percentage of smokers (8.7%) in comparison with the groups with LDL between 70-100 and < 70 (5.6% and 4.3%, respectively; p = 0.015). There is also a difference in the previous incidence of coronaropathy. In the group with LDL < 70, 28.3% of patients had already experienced a previous infarction, compared with 11.1% and 10.6% in the 70-100 and > 100 groups, respectively (p < 0.001). CONCLUSIONS The data in our study have shown that the dyslipidemia control in diabetic patients is inadequate and there is a tendency of direct association between lack of blood glucose control and lack of dyslipidemia control, in addition to the association with other cardiovascular risk factors, such as diastolic hypertension and smoking. This worsened control might be related to the plateau in the descending curve of mortality, and investments in this regard can improve the cardiovascular health in diabetic patients.

RESUMO A substituição dos dentes ausentes, por próteses implanto retidas, é uma forma previsível de reabilitação na população como um todo. Devido à similaridade da doença periodontal com a periimplantite, infere-se a hipótese de que pacientes com histórico de doença periodontal seriam mais suceptíveis a periimplantite. Este conceito vem sendo discutido e suportado por novas evidencias científicas.O objetivo desta revisão é avaliar se pacientes historicamente periodontalmente comprometidos apresentam relação com maior perda óssea peri-implantar. A literatura pertinente conclui que a reabilitação por meio de implantes em pacientes com histórico de doença periodontal é previsível e com índice de sucesso semelhantes pacientes sem histórico de periodontite.

ABSTRACT The replacement of missing teeth by implant retained prostheses is a predictable form of rehabilitation in the population as a whole. Due to thesimilarity between periodontal disease and peri-implantitis, the hypothesis is inferred that patients with a history of periodontal disease would be more susceptible to peri-implantitis. This concept has been discussed and supported by new scientific evidence. The purpose of this review was to evaluate whether there is any relationship between periodontitis and greater peri-implant bone loss in periodontally compromised patients. The pertinent literature has concluded that rehabilitation by means of implants in patients with a history of periodontal disease was predictable and has shown success rates similar to those obtained in patients with no history of periodontitis.

Porous carbon materials were prepared at low temperatures via thermal decomposition of iron, nickel and cobalt N, N -diethyldithiocarbamates (DDT). X-ray diffraction data showed two peaks at 2θ (25.5º and 43.5º) that indicate the presence of graphite-like structures. Raman spectra displayed D and G bands in the range from 1312 to 1321 cm-1 and 1587 to 1593 cm-1, respectively, which were fitted with 4 components. All spectra showed two low intensity D* (1190 cm-1) and D’’ (1500 cm-1) bands, assigned to sp2–sp3 bonds in disordered carbonaceous materials and amorphous carbon, respectively. Transmission electron microscopy images showed agglomerates of spherical particles formed by graphitic segments. The results showed that the carbon material obtained from iron N, N -diethyldithiocarbamate, Fe(DDT)3, is structurally better organized than the others and the pore size distribution curves confirmed that this material presents high degree of mesoporosity. Voltammetric curves obtained using KOH and H2SO4 electrolytes showed hysteresis behavior typical of capacitors charge/discharge process. The carbon material prepared from Fe(DDT)3 displayed the highest specific capacitance in acidic media, 59 F g-1, which was associated to its high degree of mesoporosity.

RESUMO: O desempenho técnico e econômico-financeiro de sistemas de terminação de cordeiros pantaneiros em confinamento (C) e semiconfinamento (SC) foi avaliado. Ao se analisar a rentabilidade, a eficiência econômica e a sensibilidade dos preços, foi apurado lucro em todos os cenários avaliados. A margem bruta (MB) foi de 69% e 52%, a margem liquida (ML) foi de 65% e 48% e o índice de lucratividade (IL) foi de 39% e 29%, bem como a produtividade total dos fatores (PTF) foi de R$ 1,53 e R$ 1,36, respectivamente, nos sistemas C e SC. A análise de investimento mostrou que a atividade é economicamente viável, remunerando todos os fatores de produção e o capital investido. A taxa interna de retorno foi, respectivamente, de 27% e 16% para a terminação em confinamento e semiconfinamento.

ABSTRACT: Technical and economic-financial performance of pantaneiro lamb finishing in feedlot (F) and semi-feedlot (SF) was evaluated. When analyzing the profitability, economic efficiency and the price sensitivity, was profit in all the scenarios evaluated. The gross margin (GM) was 69% and 52%, net margin (NM) was 65% and 48% and profitability index (PI) was 39% and 29%, as well as total productivity of factors (TPF) was R$1.53 and R$1.36, respectively, in the systems F and SF. Investment analysis showed that the activity is economically viable, remunerating all production factors and capital invested. Internal return tax was, respectively, 27% and 16% for the in feedlot and semi-feedlot systems.

RESUMO O aproveitamento de águas residuárias na fertirrigação de culturas agrícolas promove aumento da produtividade e qualidade dos produtos, contribuindo para a redução da poluição ambiental. O objetivo deste trabalho foi avaliar os efeitos da fertirrigação com água residuária da bovinocultura de leite (ARB) sobre os teores nutricionais em folhas do tomateiro, a produção e produtividade desta cultura em sistema orgânico de produção. Os tratamentos consistiram de seis doses de nitrogênio (0, 50, 100, 200, 300 e 400%) com base na recomendação para o tomateiro (100 kg/ha), por meio da fertirrigação orgânica com água residuária de bovinocultura de leite (ARB) composta pela água de lavagem, urinas, fezes e leite. Foram avaliados: o diâmetro do caule, comprimento dos ramos; a produção semanal de frutos por planta e a produtividade acumulada ao longo do ciclo da cultura. Na análise de concentração de nutrientes presentes na folha foram quantificados os teores de N, P, K, Ca, Mg, S, Cu, Mn, Fe, Zn e B. Os resultados foram submetidos à análise de variância (p≤0,05) e quando significativos, estes foram analisados por modelos de regressão polinomial e as médias comparadas pelo teste de Tukey (p≤0,05). Observaram-se valores máximos de produção, produtividade e acúmulo dos nutrientes nas folhas do tomateiro no tratamento com 400% da dose de nitrogênio recomendada para a cultura. Houve efeito linear crescente na produção, na produtividade acumulada e no acúmulo dos nutrientes nas folhas em função da dose de ARB aplicada. A adubação nitrogenada no cultivo orgânico do tomateiro pode ser realizada por meio da fertirrigação com a ARB e deve ser complementada na forma mineral, visando fornecer a quantidade adequada de fósforo e potássio para as plantas.

ABSTRACT The use of wastewater in the fertigation of agricultural crops increases productivity and product quality, and contributes to reduce environmental pollution. In this work, the objective was to evaluate how the use of dairy cattle wastewater (DCWW) in the fertigation of tomatoes affected production and productivity, as well as foliar nutritional contents, in an organic farming system. Treatments consisted of six nitrogen doses (0, 50, 100, 200, 300 and 400%), having N recommendation for tomato (100 kg/ha) as reference, applied using DCWW via fertigation. DCWW is made up of washing water, urine, feces and milk. Stem diameter, branch length, weekly fruit yield per plant and aggregate productivity were evaluated. N, P, K, Ca, Mg, S, Cu, Mn, Fe, Zn and B foliar contents were quantified. Data were submitted to analysis of variance (p≤0.05) and, where significant, polynomial regression models were applied. Treatment means were compared by the Tukey test (p≤0.05). The highest production, productivity and nutrient foliar accumulation were observed when 400% of the N dose recommended for tomato was used. There was an increasing linear effect on weekly and aggregate yield and also on nutrient accumulation in leaves as function of the applied N dose. N fertilization in tomato organic production can be carried out using DCWW via fertigation, but with a complementary mineral fertilization to supply plants with adequate amounts of phosphorus and potassium.

Zika virus (ZIKV) has infected thousands of Brazilian people and spread to other American countries since 2015. The introduction of ZIKV brought a strong impact to public health in Brazil. It is of utmost importance to identify a susceptible cell line that will enable the isolation and identification of the virus from patient samples, viral mass production, and testing of drug and vaccine candidates. Besides real-time reverse transcriptase polymerase chain reaction diagnosis for detecting the viral genome, virus isolation in cell lines was useful in order to study the structure of the viral particle and its behaviour inside cells. Analysis of ZIKV infected cell lines was achieved using transmission electron microscopy (TEM). Blood was obtained from a Brazilian patient during the first days after presenting with signs of the disease, and ZIKV from the patient’s blood was isolated in the C6/36 mosquito cell line. Afterwards, Vero cells were inoculated with the viral suspension, fixed six days after inoculation, embedded in polymers, and ultra-thin cut. Like dengue viruses, this flavivirus showed numerous virus particles present inside cellular vesicles thereby confirming the susceptibility of the Vero cell line to ZIKV replication. TEM is a unique technique available to make the virus visible.