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[SciELO Preprints] - Guidelines on the Diagnosis and Treatment of Hypertrophic Cardiomyopathy – 2024
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Fernandes, Fabio Simões, Marcus V. Correia, Edileide de Barros Marcondes-Braga, Fabiana G. Coelho-Filho, Otavio Rizzi Mesquita, Cláudio Tinoco Mathias-Junior, Wilson Rochitte, Carlos Eduardo Ramires, Felix José Alvarez Alves, Silvia Marinho Martins Montera, Marcelo Westerlund Lopes, Renato Delascio Oliveira-Junior, Mucio Tavares Scolari, Fernando L. Avila, Walkiria Samuel Canesin, Manoel Fernandes Bacal, Fernando Bocchi, Edimar Alcides Moura, Lídia Ana Zytynski Saad, Eduardo Benchimol Scanavacca, Mauricio I. Valdigem, Bruno Pereira Cano , Manuel Nicolas Abizaid , Alexandre Ribeiro, Henrique Barbosa Lemos-Neto, Pedro Alves Ribeiro, Gustavo Calado de Aguiar Jatene, Fabio Biscegli Dias, Ricardo Ribeiro Beck-da-Silva, Luis Rohde, Luis Eduardo P. Bittencourt, Marcelo Imbroinise Pereira, Alexandre Krieger, José Eduardo Villacorta, Humberto Martins, Wolney de Andrade Figueiredo-Neto, José Albuquerque de Cardoso , Juliano Novaes Pastore, Carlos Alberto Jatene, Ieda Biscegli Tanaka, Ana Cristina Sayuri Hotta, Viviane Tiemi Romano, Minna Moreira Dias Albuquerque, Denilson Campos de Mourilhe-Rocha, Ricardo Hajjar, Ludhmila Abrahão Brito, Fabio Sandoli de Caramelli , Bruno Calderaro, Daniela Farsky, Pedro Silvio Colafranceschi , Alexandre Siciliano Pinto, Ibraim Masciarelli Vieira , Marcelo Luiz Campos Danzmann, Luiz Claudio Barberato , Silvio Henrique Mady, Charles Martinelli-Filho, Martino Torbey , Ana Flavia Malheiros Schwartzmann, Pedro Vellosa Macedo, Ariane Vieira Scarlatelli Ferreira , Silvia Moreira Ayub Schmidt, Andre Melo , Marcelo Dantas Tavares de Lima-Filho, Moysés Oliveira Sposito, Andrei C. Brito, Flavio de Souza Biolo, Andreia Madrini-Junior, Vagner Rizk, Stéphanie Itala Mesquita, Evandro Tinoco

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Publication date: 2024-04-08

Abstract: Pt Es En

A cardiomiopatia hipertrófica (CMH) é uma forma de doença do músculo cardíaco de causa genética, caracterizada pela hipertrofia das paredes ventriculares. O diagnóstico requer detecção por métodos de imagem (Ecocardiograma ou Ressonância Magnética Cardíaca) de qualquer segmento da parede do ventrículo esquerdo com espessura > 15 mm, sem outra causa provável. A análise genética permite identificar mutações de genes codificantes de diferentes estruturas do sarcômero responsáveis pelo desenvolvimento da CMH em cerca de 60% dos casos, permitindo o rastreio de familiares e aconselhamento genético, como parte importante do manejo dos pacientes e familiares. Vários conceitos sobre a CMH foram recentemente revistos, incluindo sua prevalência de 1 em 250 indivíduos, não sendo, portanto, uma doença rara, mas subdiagnosticada. A vasta maioria dos pacientes é assintomática. Naqueles sintomáticos, a obstrução do trato de saída do ventrículo esquerdo (OTSVE) é o principal distúrbio responsável pelos sintomas, devendo-se investigar a sua presença em todos os casos. Naqueles em que o ecocardiograma em repouso ou com Manobra de Valsalva não detecta gradiente intraventricular significativo (> 30 mmHg), devem ser submetidos à ecocardiografia com esforço físico para detecção da OTSVE.   Pacientes com sintomas limitantes e grave OTSVE, refratários ao uso de betabloqueadores e verapamil, devem receber terapias de redução septal ou uso de novas drogas inibidoras da miosina cardíaca. Por fim, os pacientes adequadamente identificados com risco aumentado de morta súbita podem receber medida profilática com implante de cardiodesfibrilador implantável (CDI).

La miocardiopatía hipertrófica (MCH) es una forma de enfermedad cardíaca de origen genético, caracterizada por el engrosamiento de las paredes ventriculares. El diagnóstico requiere la detección mediante métodos de imagen (Ecocardiograma o Resonancia Magnética Cardíaca) que muestren algún segmento de la pared ventricular izquierda con un grosor > 15 mm, sin otra causa probable. El análisis genético permite identificar mutaciones en genes que codifican diferentes estructuras del sarcómero responsables del desarrollo de la MCH en aproximadamente el 60% de los casos, lo que permite el tamizaje de familiares y el asesoramiento genético, como parte importante del manejo de pacientes y familiares. Varios conceptos sobre la MCH han sido revisados recientemente, incluida su prevalencia de 1 entre 250 individuos, por lo tanto, no es una enfermedad rara, sino subdiagnosticada. La gran mayoría de los pacientes son asintomáticos. En los casos sintomáticos, la obstrucción del tracto de salida ventricular izquierdo (TSVI) es el trastorno principal responsable de los síntomas, y su presencia debe investigarse en todos los casos. En aquellos en los que el ecocardiograma en reposo o la maniobra de Valsalva no detecta un gradiente intraventricular significativo (> 30 mmHg), deben someterse a ecocardiografía de esfuerzo para detectar la obstrucción del TSVI. Los pacientes con síntomas limitantes y obstrucción grave del TSVI, refractarios al uso de betabloqueantes y verapamilo, deben recibir terapias de reducción septal o usar nuevos medicamentos inhibidores de la miosina cardíaca. Finalmente, los pacientes adecuadamente identificados con un riesgo aumentado de muerte súbita pueden recibir medidas profilácticas con el implante de un cardioversor-desfibrilador implantable (CDI).

Hypertrophic cardiomyopathy (HCM) is a form of genetically caused heart muscle disease, characterized by the thickening of the ventricular walls. Diagnosis requires detection through imaging methods (Echocardiogram or Cardiac Magnetic Resonance) showing any segment of the left ventricular wall with a thickness > 15 mm, without any other probable cause. Genetic analysis allows the identification of mutations in genes encoding different structures of the sarcomere responsible for the development of HCM in about 60% of cases, enabling screening of family members and genetic counseling, as an important part of patient and family management. Several concepts about HCM have recently been reviewed, including its prevalence of 1 in 250 individuals, hence not a rare but rather underdiagnosed disease. The vast majority of patients are asymptomatic. In symptomatic cases, obstruction of the left ventricular outflow tract (LVOT) is the primary disorder responsible for symptoms, and its presence should be investigated in all cases. In those where resting echocardiogram or Valsalva maneuver does not detect significant intraventricular gradient (> 30 mmHg), they should undergo stress echocardiography to detect LVOT obstruction. Patients with limiting symptoms and severe LVOT obstruction, refractory to beta-blockers and verapamil, should receive septal reduction therapies or use new drugs inhibiting cardiac myosin. Finally, appropriately identified patients at increased risk of sudden death may receive prophylactic measure with implantable cardioverter-defibrillator (ICD) implantation.

https://doi.org/10.1590/SciELOPreprints.8394

Characteristics of ST-Elevation Myocardial Infarction during the SARS-CoV-2 Outbreak STElevation ST Elevation SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- SARS-CoV
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Machado, Guilherme Pinheiro

; Araujo, Gustavo Neves de

; Beltrame, Rafael

; Theobald, André Luiz

; Niches, Matheus de Souza

; Fracasso, Julia Fagundes

; Milan, Victoria

; Custodio, Julia Luchese

; Cardoso, Camila Porto

; Tietz, Pedro Henrique Torres

; Reichert, Giulia Bonatto

; Schmidt, Marcia Moura

; Quadros, Alexandre Schaan de

; Wainstein, Marco Vugman

International Journal of Cardiovascular Sciences

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2024, Volume 37 elocation e20220203

Abstract: En | Text: En | PDF: En

Abstract Background The SARS-CoV-2 outbreak has led to radical transformation in social, economic, and healthcare systems. This may lead to profound indirect consequences on clinical presentation and management of patients with ST-segment–elevation myocardial infarction. Objectives The objective of this study was to describe the characteristics, management, and outcomes of patients admitted with acute myocardial infarction with ST-segment elevation (STEMI), in two tertiary reference hospitals during the SARS-CoV-2 outbreak and compare them with patients admitted in the previous year. Methods We analyzed data from a multicenter STEMI registry from reference centers in the South Region of Brazil from March 2019 to May 2021. The beginning of the COVID-19 outbreak was considered to be March 2020 and compared to the same period in 2019. Only patients with STEMI submitted to primary percutaneous coronary intervention (PCI) were included in the analysis. Mortality rates were compared with chi-square test. All hypothesis tests had a two-sided significance level of 5%. Results A total of 1169 patients admitted with STEMI were enrolled in our registry, 635 of whom were admitted during the pandemic period. The mean age of our sample was 61.6 (± 12.4) years, and 66.7% of patients were male. Pain-to-door time and door-to-balloon time were longer during the pandemic period. However, there was no difference in mortality rates or major adverse cardiovascular outcomes (MACE). Conclusions We observed a stable incidence of STEMI cases in our registry during the SARS-CoV-2 outbreak with higher pain-to-door time and door-to-balloon time, without any influence on mortality rates however. SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- social economic systems STsegment–elevation STsegmentelevation ST segment–elevation segment characteristics STsegment STEMI, , (STEMI) year 201 2021 COVID19 COVID 19 COVID-1 202 PCI (PCI analysis chisquare chi square test twosided sided 5 5% 116 63 616 61 6 61. ± ( 12.4 124 12 4 years 667 66 7 66.7 male Paintodoor Pain door doortoballoon balloon However MACE. MACE . (MACE) paintodoor pain however SARS-CoV segmentelevation (STEMI 20 COVID1 1 COVID- 11 12. 66. (MACE

https://doi.org/10.36660/ijcs.20220203

High-flow nasal therapy: a game-changer in anesthesia and perioperative medicine? Highflow High flow therapy gamechanger game changer medicine
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Maioli, Desire T.

; Andrade, Cristiano F.

; Bevilacqua Filho, Clovis T.

; Schmidt, Andre P.

Brazilian Journal of Anesthesiology

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2024, Volume 74 N. 2 elocation 744466

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.bjane.2023.09.005

Confinement and semi confinement of lambs in an integrated production system: impacts on production performance, infection by gastrointestinal nematodes, and selected blood analytes system performance nematodes
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Schmidt, Elizabeth Moreira dos Santos

; Fachiolli, Daniele Floriano

; Meirelles, Paulo Roberto de Lima

; Soutello, Ricardo Velludo Gomes de

; Pariz, Cristiano Magalhães

; Castilhos, André Michel de

; Amarante, Alessandro Francisco Talamini do

; Almeida, Fabiana Alves de

; Souza, Daniel Martins de

; Barros, Juliana da Silva

; Costa, Ciniro

Ciência Rural

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2024, Volume 54 N. 8 elocation e20230406

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: O objetivo deste experimento foi avaliar o desempenho produtivo, infecção por nematódeos gastrointestinais (GIN) e variáveis sanguíneas selecionadas, em cordeiras Corriedale durante a fase de terminação em sistema integrado lavoura-pecuária (ICLS) com duas taxas de lotação. O experimento utilizou 52 cordeiras Corriedale divididas em quatro grupos: sistema de semiconfinamento com baixa taxa de lotação por área (T1) por 70 dias; sistema de semiconfinamento com alta lotação por área (T2) por 70 dias; confinamento por 28 dias, seguido de semiconfinamento com baixa lotação por área (T3) por 42 dias; e confinamento por 28 dias, seguido de semiconfinamento com alta lotação por área (T4) por 42 dias. Peso corporal, ingestão de matéria seca, coleta de sangue e análise fecal para ovos de nematódeos foram avaliados para cada animal. As taxas de lotação não influenciaram no ganho de peso dos cordeiros semiconfinados (T1 e T2) ou nos confinados/semiconfinados (T3 e T4). Todos os tratamentos apresentaram contagens menores de EPG no final do período experimental. Os gêneros de nematódeos identificados durante o experimento foram Haemonchus e Trichostrongylus. Não houve diferença significativa (P > 0.05) para hematócrito, proteína plasmática total e média de eosinófilos entre os tratamentos. Esses resultados sugerem que o confinamento seguido de semiconfinamento em ICLS pode ser uma opção para a produção de cordeiras na fase de terminação e pode ser útil para a redução da GIN sem afetar o desempenho da produção. RESUMO produtivo (GIN selecionadas lavourapecuária lavoura pecuária (ICLS 5 grupos T1 T 7 dias T2 (T2 2 T3 4 T4 (T4 corporal seca animal (T confinadossemiconfinados confinados T4. . T4) experimental Trichostrongylus P 0.05 005 0 05 hematócrito 0.0 00 0.

ABSTRACT: This trial evaluated the production performance, gastrointestinal nematode infection (GIN), and selected blood analytes, in Corriedale lambs during the finishing phase in an integrated crop-livestock system (ICLS) with 2 stocking rates. Fifty-two Corriedale lambs were divided into 4 groups: a semi confinement system with a low stocking rate (T1) for 70 days; a semi confinement system with a high stocking rate (T2) for 70 days; confinement for 28 days, followed by semi confinement with a low stocking rate (T3) for 42 days; and confinement for 28 days, followed by semi confinement with a high stocking rate (T4) for 42 days. Body weight, dry matter intake, blood collection, and faecal analysis of nematode eggs were performed for each animal. The stocking rates did not influence body weight gain for the semiconfined lambs (T1 and T2) or for the confined/semiconfined lambs (T3 and T4). All treatments had lower EPG counts at the end of the experimental period. The nematode genera identified during the experiment trial were Haemonchus and Trichostrongylus. There were no significant differences (P > 0.05) for packed cell volume, total plasma protein, and eosinophil means between treatments. These results suggested that the confinement followed by semi confinement in an ICLS, was an option for lamb production during the finishing phase which could be useful in reducing GIN without affecting the production performance. ABSTRACT performance GIN, , (GIN) analytes croplivestock crop livestock ICLS (ICLS Fiftytwo Fifty two groups T1 T 7 days T2 (T2 T3 T4 (T4 intake collection animal (T confinedsemiconfined confined T4. . T4) period Trichostrongylus P 0.05 005 0 05 volume protein (GIN 0.0 00 0.

https://doi.org/10.1590/0103-8478cr20230406

Industry 4.0 technologies and Lean Office: perspectives to Smart Office 40 4 0 4.
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Santos, Alex Almeida dos

; Goecks, Lucas Schmidt

; Pereira, Luísa Müller

; Couto, Bruna Strapazzon do

; Korzenowski, André Luis

Production

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2024, Volume 34 elocation e20220060

Abstract: En | Text: En | PDF: En

Abstract Paper aims Due to the scarcity of research that approaches the Lean Office in conjunction with Industry 4.0 Technologies, this article aims to discuss, understand and analyze the associations between these two concepts, as well as identify gaps to be explored. Originality This research contributes with guidelines for applying Industry 4.0 Technologies in administrative areas and possibilities of an association with the Lean for the development of the Smart Office. Research method Based on a systematic review of the literature, with a basic purpose, a descriptive objective, and qualitative data, a framework for developing the Smart Office is presented. Main findings An association model between Lean Office tools and Industry 4.0 Technologies is provided. It even classifies and addresses the impact and trends in administrative environments so that managers can develop the Smart Office. Implications for theory and practice Industry 4.0 technologies have been widely discussed in companies that seek to improve processes, mainly industries; however, there are still few applications in administrative environments. The applicability and association of new technologies for Smart Office can explore future studies and contribute to the growth of these areas in addition to the creation of new articles relating to technologies in this environments. 40 4 0 4. discuss concepts explored literature purpose objective data presented provided processes industries however

https://doi.org/10.1590/0103-6513.20220060

Expert recommendations for managing difficult airways in adults and children: insights from the Brazilian Society of Anesthesiology (SBA) children SBA (SBA
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Schmidt, Andre P.

Brazilian Journal of Anesthesiology

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2024, Volume 74 N. 1 elocation 844479

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.bjane.2024.844479

Impactos do Aumento do Nível do Mar e Ocupação do Solo sobre Zonas Úmidas Costeiras: Metodologia Aplicada à Baía da Babitonga (SC) Costeiras SC (SC
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Filgueras, André Schmidt

; Silva, Tatiana Silva da

; Corrêa, Iran Carlos Stalliviere

Sociedade & Natureza

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2024, Volume 36 elocation e69403

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo As zonas úmidas costeiras são formadas por ecossistemas com potencial para resistir e até se expandirem em decorrência das mudanças climáticas. Para tanto, dependem da preservação da sua qualidade ambiental e dos serviços ecossistêmicos que prestam, entre eles a acumulação de sedimentos, fundamental para a manutenção das áreas atuais, e a presença de áreas terrestres contíguas livres da ocupação humana, permitindo o deslocamento para áreas mais elevadas, acompanhando o nível do mar. De forma a desenvolver uma metodologia para a avaliação conjunta dos impactos das mudanças climáticas e da ocupação do solo sobre ecossistemas costeiros, este trabalho está focado nos mangues da Baía da Babitonga, localizada no litoral norte de Santa Catarina. Utilizando-se projeções de elevação do nível do mar e da expansão da ocupação humana no entorno da baía a partir de dados de cobertura e uso do solo, foi possível identificar efeitos instantâneos do aumento do nível do mar e da ocupação humana a curto, médio e longo prazo, além da área potencial de expansão dos manguezais. Os resultados obtidos indicam a necessidade da expansão de áreas de conservação, considerando-se também zonas de deslocamento em direção ao continente, e no controle dos diversos fatores de estresse que podem interferir na saúde do ecossistema e em sua capacidade de manter as áreas atuais. tanto prestam sedimentos atuais elevadas costeiros Babitonga Catarina Utilizandose Utilizando curto prazo manguezais conservação considerandose considerando continente

Abstract Coastal wetlands are formed by ecosystems with the potential to resist and even expand because of climate change. However, they depend on the preservation of their environmental quality and the ecosystem services they provide, including sediment accumulation, which is essential for maintaining current areas, and the presence of contiguous land areas free from human occupation, allowing for migration to higher areas in response to sea-level rise. To develop a methodology for the joint assessment of the impacts of climate change and land occupation of coastal ecosystems, this study focuses on the mangroves of Baía da Babitonga, located on the northern coast of Santa Catarina. By using projections of sea-level rise and human occupation expansion around the bay based on land cover and land use data, it was possible to identify immediate effects of sea-level rise and human occupation in the short, medium, and long term, as well as the potential expansion area for mangroves. The results indicate the need for the expansion of conservation areas, considering displacement zones towards the mainland, and the control of various stress factors that can interfere with the ecosystem's health and its ability to maintain current areas. However provide accumulation sealevel sea level Babitonga Catarina data short medium term mainland s

https://doi.org/10.14393/sn-v36-2024-69403

Diretriz sobre Diagnóstico e Tratamento da Cardiomiopatia Hipertrófica – 2024 202 20 2
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Fernandes, Fabio

; Simões, Marcus V.

; Correia, Edileide de Barros

; Marcondes-Braga, Fabiana Goulart

; Coelho-Filho, Otavio Rizzi

; Mesquita, Cláudio Tinoco

; Mathias Junior, Wilson

; Antunes, Murillo de Oliveira

; Arteaga-Fernández, Edmundo

; Rochitte, Carlos Eduardo

; Ramires, Felix José Alvarez

; Alves, Silvia Marinho Martins

; Montera, Marcelo Westerlund

; Lopes, Renato Delascio

; Oliveira Junior, Mucio Tavares de

; Scolari, Fernando Luis

; Avila, Walkiria Samuel

; Canesin, Manoel Fernandes

; Bocchi, Edimar Alcides

; Bacal, Fernando

; Moura, Lidia Zytynski

; Saad, Eduardo Benchimol

; Scanavacca, Mauricio Ibrahim

; Valdigem, Bruno Pereira

; Cano, Manuel Nicolas

; Abizaid, Alexandre Antonio Cunha

; Ribeiro, Henrique Barbosa

; Lemos Neto, Pedro Alves

; Ribeiro, Gustavo Calado de Aguiar

; Jatene, Fabio Biscegli

; Dias, Ricardo Ribeiro

; Beck-da-Silva, Luis

; Rohde, Luis Eduardo Paim

; Bittencourt, Marcelo Imbroinise

; Pereira, Alexandre da Costa

; Krieger, José Eduardo

; Villacorta Junior, Humberto

; Martins, Wolney de Andrade

; Figueiredo Neto, José Albuquerque de

; Cardoso, Juliano Novaes

; Pastore, Carlos Alberto

; Jatene, Ieda Biscegli

; Tanaka, Ana Cristina Sayuri

; Hotta, Viviane Tiemi

; Romano, Minna Moreira Dias

; Albuquerque, Denilson Campos de

; Mourilhe-Rocha, Ricardo

; Hajjar, Ludhmila Abrahão

; Brito Junior, Fabio Sandoli de

; Caramelli, Bruno

; Calderaro, Daniela

; Farsky, Pedro Silvio

; Colafranceschi, Alexandre Siciliano

; Pinto, Ibraim Masciarelli Francisco

; Vieira, Marcelo Luiz Campos

; Danzmann, Luiz Claudio

; Barberato, Silvio Henrique

; Mady, Charles

; Martinelli Filho, Martino

; Torbey, Ana Flavia Malheiros

; Schwartzmann, Pedro Vellosa

; Macedo, Ariane Vieira Scarlatelli

; Ferreira, Silvia Moreira Ayub

; Schmidt, Andre

; Melo, Marcelo Dantas Tavares de

; Lima Filho, Moysés Oliveira

; Sposito, Andrei C.

; Brito, Flávio de Souza

; Biolo, Andreia

; Madrini Junior, Vagner

; Rizk, Stephanie Itala

; Mesquita, Evandro Tinoco

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 7 elocation e202400415

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.36660/abc.20240415

Anemia and outcomes in cardiac surgery
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Costa, Luiz Guilherme V. da

; Papa, Fabio V.

; Hare, Gregory M. T.

; Salgado Filho, Marcello F.

; Lineburger, Eric B.

; Schmidt, André P.

Brazilian Journal of Anesthesiology

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2024, Volume 74 N. 3 elocation 844504

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.bjane.2024.844504

10.

The role of cannabinoids in chronic pain management: clinical insights and challenges management
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Schmidt, André P.

Brazilian Journal of Anesthesiology

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2024, Volume 74 N. 4 elocation 844523

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.bjane.2024.844523

11.

Anesthesia and perioperative care management in patients with Dengue Fever: considerations and challenges Fever
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Carvalho, Lorena Ibiapina Mendes de

; Azi, Liana Maria Tôrres de Araújo

; Leal, Plinio da Cunha

; Lorentz, Michelle Nacur

; Diego, Luis Antonio dos Santos

; Schmidt, André P.

Brazilian Journal of Anesthesiology

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2024, Volume 74 N. 4 elocation 844511

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.bjane.2024.844511

12.

Challenges in the conservation and management of legal reserve areas in Brazilian grassland and savanna ecosystems in the face of global climate change
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Tomas, Walfrido Moraes

; Baggio, Rodrigo

; Berlinck, Christian Niel

; Camilo, André Restel

; Cunha, Cátia Nunes da

; Damasceno-Junior, Geraldo

; Durigan, Giselda

; Dutra-Silva, Rodrigo

; Fidélis, Alessandra

; Garcia, Letícia Couto

; Herrera, Heitor Miraglia

; Libonati, Renata

; Marengo, José Antonio

; Oliveira, Maxwell da Rosa

; Overbeck, Gerhard Ernst

; Pereira, Alexandre de Matos Martins

; Pillar, Valério De Patta

; Pivello, Vânia Regina

; Ribeiro, Danilo Bandini

; Ribeiro, José Felipe

; Sampaio, Alexandre Bonesso

; Santos Júnior, Antonio dos

; Schmidt, Isabel Belloni

; Soriano, Balbina Maria Araújo

; Tiepolo, Liliani Marília

; Timo, Thiago Philipe de Camargo e

; Urbanetz, Cátia

; Vieira, Daniel Luis Mascia

; Walter, Bruno Machado Teles

Pesquisa Agropecuária Brasileira

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2024, Volume 59 elocation e03491

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo As áreas de reserva legal (ARLs) são parte fundamental da estratégia brasileira de conservação, juntamente com as áreas de preservação permanente. As ARLs são destinadas à manutenção da biodiversidade e podem ser manejadas de forma sustentável. Quando essas áreas abrigam ecossistemas dependentes de fogo e pastejo, como os campos nativos e as savanas, devem ser adotadas práticas de manejo adequadas à sua conservação e ao enfrentamento dos efeitos das mudanças climáticas globais. No entanto, esse assunto ainda é pouco discutido no Brasil, e as políticas públicas não são claras a esse respeito. Este artigo de revisão descreve os ecossistemas campestres e savânicos no Brasil, os aspectos legais relacionados com o manejo das ARLs, os cenários climáticos atuais e futuros, e a relação entre clima e risco de incêndios. Também apresenta uma revisão sobre o uso do fogo e do pastejo em ecossistemas campestres e savânicos, os desafios legais relativos à sua aplicação nas ARLs e o uso de geotecnologias no monitoramento destas práticas. Conclui-se que o pastejo e o fogo, como instrumentos de manejo, são adequados às funções das ARLs, desde que praticados segundo normas legais e cientificamente embasadas para evitar os efeitos negativos do seu uso equivocado. (ARLs permanente sustentável savanas globais entanto Brasil respeito futuros incêndios Concluise Conclui se equivocado

Abstract Legal reserve areas (LRAs) are a fundamental part of the Brazilian conservation strategy, together with permanent preservation areas. The LRAs are intended to maintain biodiversity and can be managed sustainably. When these areas are home to ecosystems that depend on fire and grazing, such as native grasslands and savannas, management practices that are suitable for their conservation and for dealing with the effects of global climate change should be adopted. However, this subject is still poorly discussed in Brazil, and public policies are not clear on this matter. This review article describes the grassland and savanna ecosystems in Brazil, the legal aspects related to the management of LRAs, the current and future climate scenarios, and the relationship between climate and fire risk. It also presents a review about the use of fire and grazing in grassland and savanna ecosystems, the legal challenges related to their application in LRAs, and the use of geotechnologies to monitor these practices. The conclusion is that grazing and fire, as management tools, are adequate for LRA functions, as long as they are practiced in accordance with legal and scientifically based standards to avoid the negative effects of their incorrect use. (LRAs strategy sustainably savannas adopted However Brazil matter scenarios risk tools functions

https://doi.org/10.1590/s1678-3921.pab2024.v59.03491

13.

Diretriz de Tomografia Computadorizada e Ressonância Magnética Cardiovascular da Sociedade Brasileira de Cardiologia e do Colégio Brasileiro de Radiologia – 2024 202 20 2
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Magalhães, Tiago Augusto

; Carneiro, Adriano Camargo de Castro

; Moreira, Valéria de Melo

; Trad, Henrique Simão

; Lopes, Marly Maria Uellendahl

; Cerci, Rodrigo Julio

; Nacif, Marcelo Souto

; Schvartzman, Paulo R.

; Chagas, Antônio Carlos Palandrini

; Costa, Isabela Bispo Santos da Silva

; Schmidt, André

; Shiozaki, Afonso Akio

; Montenegro, Sérgio Tavares

; Piegas, Leopoldo Soares

; Zapparoli, Marcelo

; Nicolau, José Carlos

; Fernandes, Fabio

; Hadlich, Marcelo Souza

; Ghorayeb, Nabil

; Mesquita, Evandro Tinoco

; Gonçalves, Luiz Flávio Galvão

; Ramires, Felix José Alvarez

; Fernandes, Juliano de Lara

; Schwartzmann, Pedro Vellosa

; Rassi, Salvador

; Torreão, Jorge Andion

; Mateos, José Carlos Pachón

; Beck-da-Silva, Luiz

; Silva, Marly Conceição

; Liberato, Gabriela

; Oliveira, Gláucia Maria Moraes de

; Feitosa Filho, Gilson Soares

; Carvalho, Hilka dos Santos Moraes de

; Markman Filho, Brivaldo

; Rocha, Ricardo Paulo de Sousa

; Azevedo Filho, Clerio Francisco de

; Taratsoutchi, Flávio

; Coelho-Filho, Otavio Rizzi

; Kalil Filho, Roberto

; Hajjar, Ludhmila Abrahão

; Ishikawa, Walther Yoshiharu

; Melo, Cíntia Acosta

; Jatene, Ieda Biscegli

; Albuquerque, Andrei Skromov de

; Rimkus, Carolina de Medeiros

; Silva, Paulo Savoia Dias da

; Vieira, Thiago Dieb Ristum

; Jatene, Fabio Biscegli

; Azevedo, Guilherme Sant Anna Antunes de

; Santos, Raul D.

; Monte, Guilherme Urpia

; Ramires, José Antonio Franchini

; Bittencourt, Marcio Sommer

; Avezum, Alvaro

; Silva, Leonardo Sara da

; Abizaid, Alexandre

; Gottlieb, Ilan

; Precoma, Dalton Bertolim

; Szarf, Gilberto

; Sousa, Antônio Carlos Sobral

; Pinto, Ibraim Masciarelli Francisco

; Medeiros, Fábio de Morais

; Caramelli, Bruno

; Parga Filho, José Rodrigues

; Santos, Tiago Senra Garcia dos

; Prazeres, Carlos Eduardo Elias dos

; Lopes, Marcelo Antonio Cartaxo Queiroga

; Avila, Luiz Francisco Rodrigues de

; Scanavacca, Mauricio Ibrahim

; Gowdak, Luis Henrique Wolff

; Barberato, Silvio Henrique

; Nomura, Cesar Higa

; Rochitte, Carlos Eduardo

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 9 elocation e20240608

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.36660/abc.20240608

14.

Ablação de Fibrilação Atrial de Curta Duração e Alta Potência: Preditores de Sucesso e Reincidência em Longo Prazo – Uma Análise Multivariada Potência
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Vassallo, Fabricio

; Cunha, Christiano

; Corsino, Lucas

; Serpa, Eduardo

; Simões Jr, Aloyr

; Hespanhol, Dalton

; Lovatto, Carlos Volponi

; Gasparini, Dalbian

; Barbosa, Luiz Fernando

; Schmidt, Andre

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 12 elocation e20230837

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Background Point-by-point ablation with a high-power short-duration (HPSD) technique in atrial fibrillation (AF) ablation is used worldwide. Little data is available with the HPSD and dragging technique (DT). Objective To perform a multivariate analysis of clinical and procedural predictors of success and recurrence in HPSD with DT. Methods 214 patients in the first AF ablation in sinus rhythm were prospectively enrolled. DT with radiofrequency power of 50 W and contact force (CF) of 10–20 g and 5–10 g at a flow rate of 40 mL/min were applied on the anterior and posterior walls, respectively. Statistical significance was defined as p < 0.05. Results 143 (66.8%) males, paroxysmal AF (PAF) in 124 (57.9%), with 61.1±12.3 years and followed for 32.8±13.2 months. After 90 days, AF occurred in 43 (20.1%) patients, 19 (15.3%) from PAF, and 24 (26.7%) in persistent AF (PersAF). Multivariate analysis indicated as clinical predictors of recurrence: age ≥ 65 years (p=0.006); obesity [body mass index > 30 (p=0.009)]; CHA2DS2VASC score ≥ 3 (p=0.003); and PersAF (p=0.045). The procedural predictor of recurrence was a heart rate increase < 10% (p=0.006). Predictors of success were an increase in heart rate ≥ 30% (p=0.04) and < 60 min in left atrium time (LAT) (p=0.007). Conclusion AF ablation with DT and HPSD clinical and procedural predictors of recurrence were ≥ 65 years, obesity, a CHA2DS2VASC ≥ 3, PersAF, and a heart rate increase of < 10% after ablation. Success predictors were an increase of ≥ 30% in heart rate and low LAT (< 60 min). Pointbypoint Point by point highpower high shortduration short duration (HPSD (AF worldwide . (DT) 21 enrolled 5 CF (CF 1020 10 20 10–2 510 5–1 4 mLmin mL walls respectively 005 0 05 0.05 14 66.8% 668 66 8 (66.8% males PAF (PAF 12 57.9%, 579 57.9% , 57 9 (57.9%) 611123 61 1 61.1±12. 328132 32 13 2 32.8±13. months days 20.1% 201 (20.1% 15.3% 153 15 (15.3% 26.7% 267 26 7 (26.7% PersAF. (PersAF) 6 p=0.006 p0006 006 (p=0.006) body p=0.009 p0009 009 (p=0.009)] CHADSVASC CHA DS VASC p=0.003 p0003 003 (p=0.003) p=0.045. p0045 p=0.045 045 (p=0.045) p=0.006. p=0.04 p004 04 (p=0.04 (LAT p=0.007. p0007 p=0.007 007 (p=0.007) ( min. min) (DT 102 10– 51 5– 00 0.0 66.8 (66.8 57.9 (57.9% 61112 61.1±12 32813 32.8±13 20.1 (20.1 15.3 (15.3 26.7 (26.7 (PersAF p=0.00 p000 (p=0.006 (p=0.009) (p=0.003 (p=0.045 p=0.0 p00 (p=0.0 (p=0.007 0. 66. (66. 57. (57.9 6111 61.1±1 3281 32.8±1 20. (20. 15. (15. 26. (26. (p=0.00 (p=0.009 p=0. p0 (p=0. (66 (57. 611 61.1± 328 32.8± (20 (15 (26 p=0 (p=0 (6 (57 61.1 32.8 (2 (1 p= (p= (5 61. 32. (p

Resumo Fundamento A ablação ponto a ponto com uma técnica de curta duração e alta potência (HPSD) é utilizada em todo o mundo para fibrilação atrial (FA). Poucos dados estão disponíveis com HPSD e técnica de arrasto (DT). Objetivo Realizar uma análise multivariada dos preditores clínicos e procedimentais de sucesso e reincidência em HPSD com DT. Métodos Foram incluídos prospectivamente 214 pacientes em primeira ablação de FA em ritmo sinusal. DT com potência de radiofrequência de 50 W e força de contato (FC) de 10–20 g e 5–10 g a uma vazão de 40 mL/min foram aplicados nas paredes anterior e posterior, respectivamente. A significância estatística foi definida como p < 0,05. Resultados 143 (66,8%) homens, FA paroxística (FAP) em 124 (57,9%), com 61,1±12,3 anos e acompanhados por 32,8±13,2 meses. Após 90 dias, FA ocorreu em 43 (20,1%) pacientes, 19 (15,3%) na FAP e 24 (26,7%) na FA persistente (FAPers). A análise multivariada indicou como preditores clínicos de reincidência: idade ≥ 65 anos (p=0,006); obesidade [índice de massa corporal > 30 (p=0,009)]; pontuação CHA2DS2VASC ≥ 3 (p=0,003); e FAPers (p=0,045). O preditor procedimental de reincidência foi um aumento da frequência cardíaca < 10% (p=0,006). Os preditores de sucesso foram aumento da frequência cardíaca ≥ 30% (p=0,04) e < 60 min no tempo de átrio esquerdo (TAE) (p=0,007). Conclusão A ablação de FA com preditores clínicos e procedimentais DT e HPSD de reincidência foram ≥ 65 anos, obesidade, CHA2DS2VASC ≥ 3, FAPers e aumento da frequência cardíaca < 10% após a ablação. Os preditores de sucesso foram um aumento ≥ 30% na frequência cardíaca e TAE baixo (< 60 min). (HPSD FA. . (FA) (DT) 21 sinusal 5 FC (FC 1020 10 20 10–2 510 5–1 4 mLmin mL posterior respectivamente 005 0 05 0,05 14 66,8% 668 66 8 (66,8% homens (FAP 12 57,9%, 579 57,9% , 57 9 (57,9%) 611123 61 1 61,1±12, 328132 32 13 2 32,8±13, meses dias 20,1% 201 (20,1% 15,3% 153 15 (15,3% 26,7% 267 26 7 (26,7% FAPers. (FAPers) 6 p=0,006 p0006 006 (p=0,006) índice p=0,009 p0009 009 (p=0,009)] CHADSVASC CHA DS VASC p=0,003 p0003 003 (p=0,003) p=0,045. p0045 p=0,045 045 (p=0,045) p=0,006. p=0,04 p004 04 (p=0,04 (TAE p=0,007. p0007 p=0,007 007 (p=0,007) ( min. min) (FA (DT 102 10– 51 5– 00 0,0 66,8 (66,8 57,9 (57,9% 61112 61,1±12 32813 32,8±13 20,1 (20,1 15,3 (15,3 26,7 (26,7 (FAPers p=0,00 p000 (p=0,006 (p=0,009) (p=0,003 (p=0,045 p=0,0 p00 (p=0,0 (p=0,007 0, 66, (66, 57, (57,9 6111 61,1±1 3281 32,8±1 20, (20, 15, (15, 26, (26, (p=0,00 (p=0,009 p=0, p0 (p=0, (66 (57, 611 61,1± 328 32,8± (20 (15 (26 p=0 (p=0 (6 (57 61,1 32,8 (2 (1 p= (p= (5 61, 32, (p

https://doi.org/10.36660/abc.20230837

15.

The debate on antifibrinolytics in liver transplantation: always, never, or sometimes? transplantation always never sometimes
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Martinelli, Eduarda S.

; McCluskey, Stuart A.

; Karkouti, Keyvan

; Luzzi, Carla A.

; Bieze, Matthanja

; Malbouisson, Luiz Marcelo S.

; Schmidt, André P.

Brazilian Journal of Anesthesiology

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2024, Volume 74 N. 6 elocation 844562

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.bjane.2024.844562

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