RESUMO Introdução: a sedação e analgesia são procedimentos fundamentais para crianças submetidas a intervenções invasivas, devendo-se evitar complicações durante sua realização. A simulação in situ permite, por sua vez, capacitações nos ambientes reais de prática para aprimorar as competências técnicas e não técnicas dos profissionais para tais procedimentos. Embora seja uma ferramenta de grande utilidade, muitas vezes não é aproveitada pelo despreparo para seu planejamento e aplicação. Objetivo: elaborar e validar um cenário de simulação in situ no atendimento de urgências pediátricas com uso de sedação para realização de procedimento invasivo. Método: estudo descritivo de construção e validação de conteúdo de um cenário de simulação in situ, por meio do método Delphi, seguindo os seguintes passos: 1) definição do problema e seleção de especialistas; 2) desenvolvimento do documento inicial; 3) rodadas para validação com análise das respostas e feedback (até obtenção do consenso pelo Índice de Validação de Conteúdo); 4) relatório final. Resultados: Os especialistas indicaram sugestões devidamente aproveitadas e o cenário obteve, em todos os itens, um IVC maior que 80,0% demonstrando sua alta validade e confiabilidade. Ao usar especialistas para validar o cenário, seus insights garatem maior precisão e confiabilidade à engenharia de construção dos cenários. Conclusão: espera-se, que este estudo permita a replicação do cenário em diferentes contextos de formação facilitando e incentivando a capacitação profissional a partir de um modelo de cenário baseado em melhores evidências e práticas. Introdução invasivas devendose devendo se permite vez utilidade aplicação Objetivo invasivo Método Delphi passos 1 2 inicial 3 até Conteúdo Conteúdo) 4 final Resultados obteve itens 800 80 0 80,0 cenários Conclusão esperase, esperase espera se, espera-se práticas 8 80,

ABSTRACT Introduction: sedation and analgesia are fundamental procedures for children undergoing invasive interventions, and complications must be avoided during their implementation. In situ simulation allows, in turn, training in real practice environments to improve the technical and non-technical skills of professionals for such procedures. Although it is a very useful tool, it is often not used due to lack of preparation for its planning and application. Objective: develop and validate an in situ simulation scenario in pediatric emergency care using sedation to perform an invasive procedure. Method: descriptive study of construction and content validation of an in situ simulation scenario, using the Delphi method, following the following steps: 1) definition of the problem and selection of experts; 2) development of the initial document; 3) rounds for validation with analysis of responses and feedback (until consensus is reached by the Content Validation Index); 4) final report. Results: The experts indicated suggestions that were duly used and the scenario obtained, in all items, a CVI greater than 80.0%, demonstrating its high validity and reliability. By using experts to validate the scenario, their insights guarantee greater precision and reliability in scenario construction engineering. Conclusion: It is expected that this study will allow the replication of the scenario in different training contexts, facilitating and encouraging professional training based on a scenario model based on best evidence and practices. Introduction interventions implementation allows turn nontechnical non tool application Objective procedure Method method steps 1 2 document 3 until Index Index) 4 report Results obtained items 800 80 0 80.0% engineering Conclusion contexts practices 8 80.0 80.

Resumo O trabalho apresenta o debate sobre proteção social às famílias no contexto de crises, em que se realiza reflexões sobre o desenvolvimento das políticas de proteção social no capitalismo e os desafios postos a essas políticas diante da crise, do ajuste fiscal e do avanço das tendências neoliberais, tendo como campo de análise a realidade vivenciada pelas famílias brasileiras, considerando o contexto da pandemia do Covid-19. Entende-se, portanto, a oferta e a consolidação das seguranças sociais às famílias como responsabilidades do Estado e a concepção de seguridade social para além da legalidade constitucional. A metodologia se deu a partir de uma revisão de literatura, e de reflexões e debates acumulados construídos no processo acadêmico de pesquisa e extensão vinculadas ao Grupo de Estudos e Pesquisas em Proteção Social e Famílias (GEPPSFAM) da Universidade Federal do Tocantins (UFT). crises crise neoliberais brasileiras Covid19. Covid19 Covid 19. 19 Covid-19 Entendese, Entendese Entende se, Entende-se portanto constitucional literatura GEPPSFAM (GEPPSFAM UFT. UFT . (UFT) Covid1 1 Covid-1 (UFT Covid-

Abstract This work presents a discussion on social protection for families in the context of crises, reflecting on the development of social protection policies within capitalism and the challenges that these policies face in times of crisis, fiscal adjustment, and the advance of neoliberal trends. The analysis is centered on the reality experienced by Brazilian families, considering the context of the Covid-19 pandemic. Therefore, the provision and consolidation of social protections for families are understood as responsibilities of the State, going beyond constitutional legality and encompassing a broader concept of social security. The methodology used consisted of a literature review, as well as reflections and discussions accumulated throughout the academic research and extension process linked to the Study and Research Group on Social Protection and Families (GEPPSFAM) at Universidade Federal do Tocantins (UFT). crises crisis adjustment trends Covid19 Covid 19 Covid-1 pandemic Therefore State security review GEPPSFAM (GEPPSFAM UFT. UFT . (UFT) Covid1 1 Covid- (UFT

ABSTRACT. This study aimed to perform a strategic diagnosis on a property specialized in breeding, rearing and finishing beef cattle in the southern region of Piauí. It was conducted at Agropecuária Alvorada, located in the countryside, municipality of Bom Jesus, PI, Brazil. The farm develops the full cycle of beef cattle production, which is divided into breeding, rearing and finishing. A SWOT analysis (which stands for Strengths, Weaknesses, Opportunities and Threats) was carried out, consisting of an assessment of the property’s internal and external environments. To evaluate the internal environment, an interview was held for data collection by means of questionnaires. The evaluation included: breeding management, sanitary management, nutritional management, infrastructure, workforce, technologies used in pasture formation, conservation and recovery, pasture management and zootechnical indices. To analyze the external environment, a group of people (experts) with deep knowledge of the subject addressed during the study was used as source of information. A matrix was generated with all the information from the SWOT analysis, strengths, weaknesses, opportunities and threats, culminating with the establishment of strategies to increase the productive efficiency of the cattle raising activity.

ABSTRACT Molecular imaging markers can be used to differentiate between infection and aseptic inflammation, determine the severity of infection, and monitor treatment responses. One of these markers is ubiquicidin(29-41) (UBI), a cationic peptide fragment that binds to the bacterial membrane wall and is labeled with gallium-68 (68Ga), a positron emitter radioisotope. The use of UBI in positron emission tomography (PET)/computed tomography (CT) for improved detection of lesions has been receiving considerable attention recently. Herein, we report the first case of 68Ga-UBI PET/CT performed in Brazil. The patient was a 39-year-old woman referred for a scan to confirm a clinical suspicion of chronic osteomyelitis of her fractured left tibia. PET images revealed radiotracer uptake near the posterior contour of the tibial fracture focus and the fixation plate, in the soft tissue around the distal half of the tibia, and in the non-consolidated fracture of the left distal fibula. Surgery for local cleaning was performed, and culture of a specimen collected from the surgical site confirmed the presence of Staphylococcus aureus. In the present case, 68Ga-UBI PET/CT, a non-invasive imaging modality, identified the infection foci in vivo, indicating its potential for clinical use. inflammation responses ubiquicidin2941 ubiquicidin 29 41 ubiquicidin(29-41 UBI, , (UBI) gallium68 gallium 68 gallium-6 68Ga, 68Ga Ga (68Ga) radioisotope PET/computed PETcomputed /computed computed CT (CT recently Herein 68GaUBI GaUBI PETCT Brazil 39yearold yearold 39 year old tibia plate nonconsolidated non consolidated fibula aureus noninvasive invasive modality vivo ubiquicidin294 2 4 ubiquicidin(29-4 (UBI gallium6 6 gallium- (68Ga 3 ubiquicidin29 ubiquicidin(29- ubiquicidin2 ubiquicidin(29 ubiquicidin(2 ubiquicidin(

ABSTRACT OBJECTIVE To evaluate the quality of information on gestational syphilis (GS) and congenital syphilis (CS) on the Sistema de Informação de Agravos de Notificação (SINAN-Syphilis Brazil – Notifiable Diseases Information System) by compiling and validating completeness indicators between 2007 and 2018. METHODS Overall, care, and socioeconomic completeness scores were compiled based on selected variables, by using ad hoc weights assigned by experts. The completeness scores were analysed, considering the region and area of residence, the pregnant woman’s race/colour, and the year of case notification. Pearson’s correlation coefficients were used to validate the scores obtained by the weighted average method, compared with the values obtained by principal component analysis (PCA). RESULTS Most selected variables presented a good or excellent degree of completeness for GS and CS, except for clinical classification, pregnant woman’s level of education, partner’s treatment, and child’s race/colour, which were classified as poor or very poor. The overall (89.93% versus 89.69%) and socioeconomic (88.71% versus 88.24%) completeness scores for GS and CS, respectively, were classified as regular, whereas the care score (GS-90.88%, and CS-90.72%) was good, despite improvements over time. Differences in the overall, care and socioeconomic completeness scores according to region, area of residence, and ethnic-racial groups were reported for syphilis notifications. The completeness scores estimated by the weighted average method and PCA showed a strong linear correlation (> 0.90). CONCLUSION The completeness of GS and CS notifications has been improving in recent years, highlighting the variables that form the care score, compared with the socioeconomic scores, despite differences between regions, area of residence, and ethnic-racial groups. The weighted average was a viable methodological alternative easily operationalised to estimate data completeness scores, allowing routine monitoring of the completeness of gestational and congenital syphilis records. (GS (CS SINANSyphilis SINAN Syphilis System 200 2018 Overall experts analysed residence womans woman s racecolour race colour race/colour notification Pearsons Pearson PCA. . (PCA) classification education partners partner treatment childs child 89.93% 8993 89 93 (89.93 89.69% 8969 69 88.71% 8871 88 71 (88.71 88.24% 8824 24 respectively regular GS90.88%, GS9088 90.88%, 90 (GS-90.88% CS90.72% CS9072 90.72% 72 CS-90.72% time ethnicracial ethnic racial > ( 0.90. 090 0.90 0 0.90) years regions records 20 201 (PCA 89.93 899 8 9 (89.9 89.69 896 6 88.71 887 7 (88.7 88.24 882 2 GS90 GS90.88% GS908 9088 90.88% (GS-90.88 CS90 CS90.72 CS907 9072 90.72 CS-90.72 09 0.9 89.9 (89. 89.6 88.7 (88. 88.2 GS9 GS90.88 908 90.88 (GS-90.8 CS9 CS90.7 907 90.7 CS-90.7 0. 89. (89 88. (88 GS90.8 90.8 (GS-90. CS90. 90. CS-90. (8 GS90. (GS-90 CS-90 (GS-9 CS-9 (GS- CS-

ABSTRACT OBJECTIVE To evaluate the quality of information on gestational syphilis (GS) and congenital syphilis (CS) on the Sistema de Informação de Agravos de Notificação (SINAN-Syphilis Brazil – Notifiable Diseases Information System) by compiling and validating completeness indicators between 2007 and 2018. METHODS Overall, care, and socioeconomic completeness scores were compiled based on selected variables, by using ad hoc weights assigned by experts. The completeness scores were analysed, considering the region and area of residence, the pregnant woman’s race/colour, and the year of case notification. Pearson’s correlation coefficients were used to validate the scores obtained by the weighted average method, compared with the values obtained by principal component analysis (PCA). RESULTS Most selected variables presented a good or excellent degree of completeness for GS and CS, except for clinical classification, pregnant woman’s level of education, partner’s treatment, and child’s race/colour, which were classified as poor or very poor. The overall (89.93% versus 89.69%) and socioeconomic (88.71% versus 88.24%) completeness scores for GS and CS, respectively, were classified as regular, whereas the care score (GS-90.88%, and CS-90.72%) was good, despite improvements over time. Differences in the overall, care and socioeconomic completeness scores according to region, area of residence, and ethnic-racial groups were reported for syphilis notifications. The completeness scores estimated by the weighted average method and PCA showed a strong linear correlation (> 0.90). CONCLUSION The completeness of GS and CS notifications has been improving in recent years, highlighting the variables that form the care score, compared with the socioeconomic scores, despite differences between regions, area of residence, and ethnic-racial groups. The weighted average was a viable methodological alternative easily operationalised to estimate data completeness scores, allowing routine monitoring of the completeness of gestational and congenital syphilis records.

Resumo: O artigo propõe apresentar as direções do sistema de proteção social no Uruguai desde sua construção até a atualidade. Para isso foi realizado levantamento bibliográfico com caráter exploratório. Este estudo aponta que o sistema de proteção social uruguaio seguiu diferentes e, por vezes, múltiplas direções desde a lógica compensatória, solidária, universal, democrática, contributiva, de pleno emprego, regulada, repressora, até neoliberal.

Abstract: The aim of this paper is to present the courses of action of the social protection system in Uruguay, since its inception until the present, for which bibliographical survey of exploratory nature was carried out. The results of the survey show that the Uruguayan protection system has followed diverse, sometimes multiple, directions, be them compensatory, solidaristic, universal, democratic, contributive, full-employment, regulatory, repressive, and even neoliberal.

Abstract: The aim of this paper is to present the courses of action of the social protection system in Uruguay, since its inception until the present, for which bibliographical survey of exploratory nature was carried out. The results of the survey show that the Uruguayan protection system has followed diverse, sometimes multiple, directions, be them compensatory, solidaristic, universal, democratic, contributive, full-employment, regulatory, repressive, and even neoliberal.

Resumen: El artículo propone presentar las direcciones del sistema de protección social en el Uruguay desde su construcción hasta la actualidad. Para eso se ha realizado una investigación bibliográfica con carácter exploratorio. Este estudio apunta que el sistema de protección social uruguayo ha seguido diferentes y, muchas veces, múltiples direcciones sea de la lógica compensatoria, solidaria, universal, democrática, contributiva, de pleno empleo, regulada, represora y aun neoliberal.

Resumo O Parque Estadual Mata da Pimenteira (PEMP) é um importante remanescente de caatinga na região semiárida de Pernambuco, Brasil. O parque possui grande biodiversidade, mas relativamente poucos estudos taxonômicos foram realizados na área. Apresentamos um estudo taxonômico de Ipomoea no PEMP com base em observações de campo e coleções depositadas no Herbário do Semiárido do Brasil - UAST/UFRPE (HESBRA). As espécies foram identificadas com base em literatura especializada, comparação com imagens de tipos disponíveis online e protólogos. Foram identificadas quatorze espécies de Ipomoea - mais do que o triplo do número conhecido anteriormente. Duas espécies de Ipomoea registradas no PEMP são endêmicas do Brasil (I. bahiensis e I. brasiliana), outras três são exclusivas do domínio Caatinga (I. marcellia, I. rosea e I. tenera), e as demais são amplamente distribuídas na América do Sul. O hábito, tipo e forma da lâmina foliar e sépalas, tamanho e formato da corola, e presença ou ausência de rostro subapical nas sépalas externas foram às características distintivas mais relevantes. São apresentados uma chave de identificação, descrições, comentários sobre distribuição e características diagnósticas e dados fenológicos das espécies.

Abstract The Mata da Pimenteira State Park (MPSP) is an important remnant of caatinga vegetation in the semiarid region of Pernambuco state, Brazil. The park holds great biodiversity, but relatively few taxonomic studies have been undertaken in the area. We present a taxonomic study of Ipomoea in the MPSP based on field observations and collections deposited in the Herbarium of the Semiarid of Brazil - UAST / UFRPE (HESBRA). The species were identified based on the specialized literature, comparisons with type images available online, and protologues. Fourteen species of Ipomoea were identified - more than three times the previously known number. Two Ipomoea species recorded in the MPSP are endemic to Brazil (I. bahiensis and I. brasiliana), three others are exclusive to the Caatinga domain (I. marcellia, I. rosea, and I. tenera), and the remaining are widely distributed in South America. The habit, type and shape of leaf blade and sepals, corolla size and shapes, and presence or absence of subapical rostrum on the external sepals were the most relevant distinctive characteristics. An identification key, descriptions, comments on distribution and diagnostic characteristics, and phenological data of the species are presented.

Resumo: O objetivo deste trabalho foi avaliar a influência da inclusão de goma de soja (Glycine max) na dieta de poedeiras comerciais sobre a produção de ovos, a qualidade externa e interna dos ovos, e a viabilidade econômica, bem como da temperatura e do tempo de armazenamento sobre a estabilidade oxidativa dos ovos. Cento e oitenta poedeiras Lohmann-LSL com 40 semanas de idade foram alimentadas com 0, 1, 2, 3, 4 e 5% de goma de soja na dieta. Na análise econômica, foram considerados o desempenho produtivo médio das poedeiras e o custo da ração. Para a avaliação da estabilidade oxidativa, os ovos foram armazenados à temperatura ambiente (~ 30oC) ou sob refrigeração (5oC) por 0, 7 e 21 dias. A inclusão de goma de soja na dieta aumentou o consumo de ração e também a produção, o peso médio e a massa dos ovos. A goma de soja melhorou os parâmetros de qualidade externa e interna dos ovos, mas reduziu a unidade de Haugh. A estabilidade oxidativa foi maior nos ovos de galinhas alimentadas com 4% de goma, a 5oC, por 21 dias; entretanto, o maior retorno econômico foi com 1% de goma. A inclusão de goma de soja promove melhorias na produção, na qualidade externa e interna, e na estabilidade oxidativa dos ovos de poedeiras comerciais.

Abstract: The objective of this work was to evaluate the influence of the inclusion of soybean (Glycine max) gum in the diet of laying hens on egg production, egg external and internal quality, and economic viability, as well as of temperature and storage time on the oxidative stability of eggs. One hundred and eighty 40-week-old Lohmann-LSL layers were fed 0, 1, 2, 3, 4, and 5% soybean gum in the diet. In the economic analysis, the average productive performance of the layers and the cost of feed were considered. In order to evaluate oxidative stability, eggs were stored at room temperature (~30oC) or refrigerated (5oC) for 0, 7, and 21 days. The inclusion of soybean gum in the diet increased feed intake and also egg production, average weight, and mass. Soybean gum improved external and internal egg quality parameters, but reduced the Haugh unit. Oxidative stability was higher in eggs from hens fed 4% gum, at 5oC, for 21 days; however, the largest economic return was with 1% gum. The inclusion of soybean gum promotes improvements in the production, external and internal quality, and oxidative stability of eggs from commercial laying hens.

Abstract The aim of this study was to evaluate the effect of periodontal treatment on the salivary cytokine levels and clinical parameters of individuals with cerebral palsy (CP) with gingivitis. A non-randomized, clinical trial was conducted in individuals diagnosed with spastic CP. Thirty-eight individuals were enrolled in the study and were categorized according to gingival index scores between 0-1 or 2-3, assigned to groups G2 or G1, respectively. Periodontal treatment comprised oral hygiene instructions, conventional mechanical treatment and 0.12% chlorhexidine applied as an adjunct. Clinical parameters and saliva samples were collected at baseline and at the 15-day follow-up visit. Bleeding on probing and periodontal screening and recording were determined. Non-stimulated saliva samples were obtained, and the salivary flow rate, the osmolality and the levels of cytokines IL-1β, IL-6, IL-8, IL-10, TNF-α and IL-12p70 were evaluated by a cytometric bead array. The Wilcoxon test, the Mann-Whitney test, Spearman correlation analysis, Poisson regression analysis and an adjusted analysis were performed (α = 0.05). The groups differed significantly in periodontal clinical parameters at baseline and at follow-up. Salivary flow rate and osmolality were similar in both groups at both timepoints. However, TNF-α and IL-1β levels were higher in G1 than in G2 at baseline. Mechanical treatment resulted in improved clinical parameters for both groups. Furthermore, mechanical treatment resulted in a significant reduction in salivary IL-1β and IL-8 levels for both groups after treatment. Periodontal treatment performed in individuals with CP and gingivitis reduces the levels of TNF-α, IL-1β, IL-6 and IL-8.

Objective: To analyze the prevalence of common mental disorders (CMD) assessed with the Self Reporting Questionnaire (SRQ-20), using the established cutoff point, and comparing it with the results of a joint correspondence factor analysis (CFA) and cluster analysis and of a latent class analysis (LCA). Methods: A cross-sectional study was carried out in an urban sample of 1,095 women aged 19 to 55 years. Joint CFA-cluster analysis and LCA were used. Results: We found a high prevalence of CMD, regardless of classification method (37.6% when using the cutoff point; 44.4% and 52% for LCA and joint CFA-cluster, respectively). The alternative analysis strategies describe the cases more efficiently when compared to the traditional cutoff method, especially regarding more severe symptoms. Both alternative strategies also provide a description of the SRQ-20 dimensions in their particularities, which may be useful for the planning and implementation of specific actions in a given population. Conclusion: The SRQ-20 cutoff point seems to underestimate the magnitude of CMD among women. The alternative methods of analysis presented herein highlight the different possibilities of using this important instrument of screening for mental health.

Resumo Objetivo Há poucos dados sobre a associação entre autopercepção corporal e padrões alimentares no Brasil. Assim, este estudo teve como objetivo explorar a relação entre insatisfação com a imagem corporal (IIC) e padrões alimentares de acordo com o estado antropométrico em adolescentes. Métodos Um estudo transversal com 1.496 adolescentes foi conduzido. Os participantes preencheram o Questionário de Imagem Corporal. Dados demográficos, antropométricos e socioeconômicos foram coletados, bem como informações relacionadas ao desenvolvimento puberal e ao consumo alimentar. Foi feita uma regressão logística para avaliar as associações de interesse. Resultados A IIC foi identificada em 19,5% dos adolescentes. Três padrões alimentares foram identificados: (1) O padrão Ocidental, composto de doces e açúcares, refrigerantes, pratos típicos, artigos de pastelaria, fast food, carne bovina, leite e laticínios, (2) o padrão Tradicional, composto de óleos, frango, peixe, ovos, produtos de carne processada, cereais (arroz, farinha de mandioca, massas etc.), feijão cozido e pão e (3) o padrão Restritivo, composto de granola, raízes, verduras e frutas. Entre adolescentes acima do peso/obesos, os dados indicaram uma associação negativa entre IIC leve [RC = 0,240 (0,100; 0,576)] e IIC moderada [RC = 0,235 (0,086; 0,645)] e padrões alimentares ocidentais. Além disso, nesse grupo, houve uma associação positiva entre a IIC grave e o padrão Restritivo [RC = 2,794 (1,178; 6,630)]. Conclusão Entre adolescentes acima do peso/obesos, aqueles com IIC (leve e moderada) apresentaram menor probabilidade de seguir um padrão alimentar Ocidental em comparação com os satisfeitos com sua imagem corporal. Além disso, nesse grupo, adolescentes com IIC grave apresentaram maior probabilidade de seguir um padrão Restritivo.

Abstract Objective There is a lack of data on the association between body self-perception and eating patterns in Brazil. Thus, this study aimed to explore the relationship between body image dissatisfaction and eating patterns by the anthropometric status in adolescents. Methods A cross-sectional study of 1496 adolescents was conducted. The participants completed the Body Shape Questionnaire. Demographic, anthropometric, and socioeconomic data were collected, as well as information regarding the pubertal development and dietary intake. Logistic regression was performed to evaluate the associations of interest. Results Body image dissatisfaction was identified in 19.5% of the adolescents. Three dietary patterns were identified: (1) the Western pattern was composed of sweets and sugars, soft drinks, typical dishes, pastries, fast food, beef, milk, and dairy products; (2) the Traditional pattern was composed of oils, chicken, fish, eggs, processed meat products, cereals (rice, cassava flour, pasta, etc.), baked beans, and bread; and (3) the Restrictive pattern was composed of granola, roots, vegetables, and fruit. Among overweight/obese adolescents, the data indicated a negative association of slight body image dissatisfaction (OR: 0.240 [0.100; 0.576]) and moderate body image dissatisfaction (OR: 0.235 [0.086; 0.645]) with the Western dietary pattern. Additionally, in this group, there was a positive association between high body image dissatisfaction and the Restrictive pattern (OR: 2.794 [1.178; 6.630]). Conclusion Amongst overweight/obese adolescents, those with slight and moderate body image dissatisfaction were less likely to follow a Western-like dietary pattern when compared with those satisfied with their body image. Additionally, in this group, adolescents with high body image dissatisfaction was more likely to follow a restrictive pattern.

ABSTRACT Considering the reported activity of carvone in the literature, this study aimed to evaluate the antimicrobial, cytotoxic and chemopreventive activities of (+)- and (-)-carvone, (+)- and (-)- hydroxydihydrocarvone and α,β-epoxycarvone. (+)-Hydroxydihydrocarvone (HC+), (-)-hydroxydihydrocarvone (HC-) and α,β-epoxycarvone (EP) were obtained by synthesis using (+)-carvone (C+) or (-)-carvone (C-) as precursors. The antifungal activity (MIC and MFC) were evaluated against Candida parapsilosis, C. tropicalis, C. krusei and C. albicans and the antibacterial activity (MIC and MBC) against Escherichia coli and Staphylococcus aureus. The cytotoxicity assays were performed with human cancer cell lines HepG-2 and SiHa and the normal strain MRC-5 through sulphorrodamine B assay. Chemoprevention was evaluated through quinone reductase assay. Our results showed no cytotoxicity on tumor and normal cell lines and no induction of the quinone reductase enzyme. C- and HC- presented activity against E. coli. All compounds presented weak antifungal activity against C. tropicalis and C. parapsilosis. EP and C+ showed moderate activity against C. krusei. Results suggest the potential use of carvones and its derivatives as antifungal agents against Candida yeasts. The absence of cytotoxicity in cell lines indicates safety in the use of these compounds.

Resumo Este artigo se propõe a refletir sobre como, no Brasil, as formulações políticas e legais acerca das ações afirmativas de cunhos social e racial no ensino superior articulam e estão articuladas a partir de distintas representações sobre os sujeitos e os lugares que eles ocupam na estrutura social. Partimos da breve caracterização dos dispositivos legais e das políticas implantadas a partir do século XX sobre o tema; analisamos a literatura que aborda as representações sociais sobre a recente implantação das políticas de ação afirmativa; e, por fim, discutimos duas concepções opostas de ação afirmativa, a Lei de cotas e o PIMESP. Pontuamos que tais medidas respondem a diferentes formas de representar desigualdades, merecimento e excelência acadêmica. Discute-se ainda, a suficiência da tradicional acepção de merecimento, o mérito pessoal, para julgar e determinar quem e como deve ingressar na universidade pública.

Abstract This article aims to reflect on how, in Brazil, the political and legal formulations about social and racial affirmative action in higher education, articulate and are articulated from different representations about the subjects and the places they occupy in the social structure. The starting point was a brief description of the legal provisions and policies implemented from the twentieth century on the topic. Then, we analyzed the literature addressing the social representations about the recent implementation of affirmative action. And finally, we discussed two opposing conceptions of affirmative action, Quotas Law and PIMESP. We pointed out that these measures respond to different ways of representing inequality, worthiness and academic excellence. It was also discussed the sufficiency of the traditional sense of worthiness, personal merit, to judge and determine who and how someone should join the public university.

Resumen Este artículo se propone reflexionar sobre cómo, en Brasil, las formulaciones políticas y legales acerca de las acciones afirmativas de cuños social y racial en la enseñanza superior, articulan y están articuladas a partir de distintas representaciones sobre los sujetos y los lugares que ellos ocupan en la estructura social. Para tanto: partimos de la breve caracterización de los dispositivos legales y de las políticas implantadas a partir del siglo XX sobre el tema; analizamos la literatura que aborda las representaciones sociales sobre la reciente implantación de las políticas de acción afirmativa; y, finalmente, discutimos dos concepciones opuestas de acción afirmativa, la Ley de cuotas y el PIMESP. Señalamos puntualmente que tales medidas responden a diferentes formas de representar desigualdades, merecimiento y excelencia académica. Se discute, también, la suficiencia de la tradicional acepción de merecimiento, el mérito personal, para juzgar y determinar quién y cómo debe ingresar a la universidad pública.