RESUMO: O estudo de adaptabilidade, estabilidade e produtividade é importante para selecionar e recomendar genótipos superiores. Esse fato é particularmente válido para a introdução de cultivares de feijão comum no Rio de Janeiro, Brasil, cuja produção é ínfima e não atende a demanda interna. Assim, este trabalho teve como objetivo estimar parâmetros genéticos e ganhos de seleção e realizar uma seleção simultânea para adaptabilidade, estabilidade e produtividade de genótipos de feijão preto através de modelos mistos. O estudo foi realizado em três municípios do estado do Rio de Janeiro e em três anos agrícolas. Os ensaios foram instalados em delineamento de blocos casualizados com 11 genótipos e três repetições. Observou-se alta herdabilidade média (81%), acurácia seletiva (90%) e boas perspectivas de seleção. Também foram observados ganhos satisfatórios para a característica entre 1,03 e 9,49%. A seleção simultânea foi eficiente e permitiu selecionar duas linhagens de feijão preto CNFP (15290 e 15361) como sendo as mais produtivas, adaptáveis e estáveis e, portanto, têm potencial para serem lançadas como novas cultivares de feijão preto para o estado do Rio de Janeiro. RESUMO adaptabilidade superiores Brasil interna Assim mistos agrícolas 1 repetições Observouse Observou se 81%, 81 81% , (81%) 90% 90 (90% 103 03 1,0 949 9 49 9,49% 15290 (1529 15361 produtivas portanto 8 (81% (90 10 0 1, 94 4 9,49 1529 (152 1536 (81 (9 9,4 152 (15 153 (8 ( 9, 15 (1

ABSTRACT: The study of adaptability, stability, and productivity is essential for selecting and recommending superior genotypes. This fact is particularly the case for the introduction of common bean cultivars in Rio de Janeiro, Brazil, whose production is negligible and does not meet the internal demand. Thus, this study estimated genetic parameters and selection gains and undertake a simultaneous selection for adaptability, stability, and productivity in black bean genotypes via mixed models. The investigation was carried out in three municipalities in the state of Rio de Janeiro during three crop years. The trials were set up in a randomized block design with 11 genotypes and three replications. High mean heritability (81%) and selection accuracy (90%), as well as good selection prospects, were observed. Gains between 1.03 and 9.49% were achieved for grain yield. Simultaneous selection was efficient, indicating two black bean lines (CNFP 15290 and CNFP 15361) as the most productive, adaptable, and stable. As such, these lines have the potential to be released as new black bean cultivars for the state of Rio de Janeiro. ABSTRACT adaptability stability Brazil demand Thus models years 1 replications 81% 81 (81% 90%, 90 90% , (90%) prospects observed 103 03 1.0 949 9 49 9.49 yield efficient 1529 15361 productive adaptable stable such 8 (81 (90% 10 0 1. 94 4 9.4 152 1536 (8 (90 9. 15 153 ( (9

RESUMO Objetivo: Descrever um protocolo de avaliação cinemática da marcha e identificar suas principais alterações, em indivíduos com mielopatia espondilótica cervical (MEC), em comparação com pacientes saudáveis. Métodos: 14 pacientes com diagnóstico de MEC foram incluídos e submetidos à análise tridimensional da marcha. Capturamos o movimento dos pacientes com câmeras de emissão infravermelha, que identificaram marcadores de rastreamento posicionados nos membros inferiores. Adquirimos sua posição de referência e os pacientes caminharam por uma passarela emborrachada. As variáveis foram analisadas pelo Gait Profile Score (GPS) e Movement Analysis Profile (MAP), sendo seus resultados analisados pelo teste t de Student com intervalo de confiança de 95%. Utilizamos o software R Core Team (2016) para análise estatística. Comparamos graficamente nossos resultados com dados de pacientes saudáveis. Resultados: Ao comparar os dados cinemáticos bilateralmente, não houve diferenças estatísticas. A análise gráfica evidenciou alterações na marcha do paciente em comparação a indivíduos saudáveis. Houve diferenças em todos os movimentos, com discrepância mais significativa na flexão e extensão do quadril e joelho, dorsiflexão e flexão plantar e rotação interna e externa do quadril. Conclusão: Descrevemos um protocolo de avaliação cinemática da marcha utilizando GPS e MAP e apresentamos as diferenças da marcha de pacientes com MEC, em comparação com indivíduos saudáveis. Nível de Evidência II, Estudo prospectivo. Objetivo , (MEC) saudáveis Métodos 1 infravermelha inferiores emborrachada (GPS MAP, (MAP) 95 95% 2016 (2016 estatística Resultados bilateralmente estatísticas movimentos joelho Conclusão II prospectivo (MEC (MAP 9 201 (201 20 (20 2 (2 (

ABSTRACT Objective: This study aims to describe a kinematic gait assessment protocol and identify its main alterations in individuals with cervical spondylotic myelopathy (CSM) compared to healthy patients. Methods: In total, 14 patients diagnosed with CSM were enrolled and submitted to a three-dimensional gait analysis. The movement of patients was captured with infrared emission cameras that identified tracking markers placed on the lower limbs. Reference positions were used, and the patients walked along a rubberized walkway. The Gait Profile Score (GPS) and Movement Analysis Profile (MAP) were used to analyze variables. Results were subjected to a Student’s t-test at 95% confidence interval. The R Core Team (2016) software was used for statistical analysis, graphically comparing the study results with data from healthy patients. Results: When comparing the kinematic data bilaterally, no statistical differences were found. However, graphical analysis showed changes in the gait of patients with CSM compared to healthy individuals. There were differences in all movements, with a more significant discrepancy in hip and knee flexion and extension, dorsiflexion and plantar flexion, and internal and external hip rotation. Conclusion: We describe a protocol for gait kinematics assessment using GPS and MAP, and we presented the differences in gait kinematics in patients with CSM compared to healthy individuals. Level of Evidence II, Prospective study. Objective (CSM Methods total 1 threedimensional three dimensional limbs walkway (GPS MAP (MAP variables Students Student s ttest t test 95 interval 2016 (2016 bilaterally found However movements extension rotation Conclusion II 9 201 (201 20 (20 2 (2 (

Abstract The incorporation of antioxidants into sunscreens may provide additional skin photoprotection against the harmful photobiological effects of ultraviolet radiation. The present study evaluated the applicability of a screening approach to the assessment of the antioxidant and photoprotective properties of vitamin C, vitamin E, and coenzyme Q10 and then determined the performance of the most effective antioxidant in a sunscreen formulation. Antioxidant activity was assessed by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, 2,2`-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay, and oxygen radical absorbance capacity (ORAC) assay, and the photoprotective potential was investigated by the yeast photoprotection assay. The antioxidant with the best effect was incorporated into sunscreen formulations which were evaluated for 120 days regarding their in vitro photoprotective parameters. Vitamin C showed high antioxidant capacity as well as a photoprotective potential against simulated solar irradiation applied for times longer than 1 h. Although the Sun Protection Factor, UVA/UVB ratio and critical wavelength did not differed significantly (p<0.05) between the formulation blank and the formulations containing 0.5% or 1% vitamin C, formulations with vitamin C kept their photostability for 6 months. Consequently, the proposed screening approach seems to be promising for the development of an antisolar photostable formulation containing vitamin C as an antioxidant. radiation E Q Q1 2,2diphenyl1picrylhydrazyl 22diphenyl1picrylhydrazyl diphenylpicrylhydrazyl 2,2 diphenyl picrylhydrazyl 2 DPPH (DPPH assay 2,2`azinobis 22azinobis azinobis 2,2` azino bis 3ethylbenzothiazoline6sulfonic ethylbenzothiazolinesulfonic 3 ethylbenzothiazoline sulfonic acid ABTS (ABTS ORAC (ORAC 12 parameters h Factor UVAUVB UVA UVB p<0.05 p005 p 0 05 (p<0.05 5 0.5 months Consequently 2diphenyl1picrylhydrazyl 22 2, p<0.0 p00 (p<0.0 0. p<0. p0 (p<0. p<0 (p<0 p< (p< (p

ABSTRACT The methicillin-resistant Staphylococcus aureus (MRSA) USA300-Latin American variant (USA300-LV) lineage is well documented in northern Latin American countries. It has replaced established clones in hospital environments. We herein report a systemic infection caused by a USA300-LV isolate in a 15-year-old boy, from a low-income area of Rio de Janeiro, previously colonized by the same strain. During hospital stay, seven pvl-positive MRSA USA300-LV isolates were recovered by nasal swab, blood and abscess secretion. The patient underwent intravenous vancomycin, daptomycin, and oral sulfamethoxazole/trimethoprim, and was discharged after 45 days after full recovery. This is the first documented case of a community-acquired MRSA infection caused by the USA300-LV variant in Brazil in a previously colonized adolescent with no history of recent travel outside of Rio de Janeiro. The need for improved surveillance programs to detect MRSA colonization in order to control the spread of hypervirulent lineages among community and hospital settings is highlighted. methicillinresistant methicillin resistant (MRSA USA300Latin USALatin USA300 USA USA300LV USALV LV (USA300-LV countries environments 15yearold yearold 15 year old boy lowincome low income Janeiro strain stay pvlpositive pvl positive swab secretion vancomycin daptomycin sulfamethoxazoletrimethoprim sulfamethoxazole trimethoprim sulfamethoxazole/trimethoprim 4 recovery communityacquired acquired highlighted USA30 1 USA3

Abstract The study of adaptability and yield stability is essential for the selection and recommendation of new cultivars. Thus, this study determined the adaptability and yield stability of black bean genotypes for cultivar recommendation using a GGE biplot. To this end, nine trials were carried out at different locations in the state of Rio de Janeiro. Eleven genotypes were evaluated in three growing seasons, in a randomized block design, with three replications. Adaptability and stability of grain yield were analyzed by the GGE biplot method. The effects of genotypes, environments and of the genotype - environment interaction were significant, which explained the different responses of the genotypes to the tested environments. The GGE biplot analysis revealed Macaé as an ideal district for testing and high yield, adaptability, and stability of performance were observed for genotype CNFP 15290, which can be recommended for grain production in the state of Rio de Janeiro. cultivars Thus end Janeiro seasons design replications method significant 15290 1529 152 15 1

ABSTRACT Elephant grass stands out among lignocellulosic biomass plants utilized for second-generation biofuel production due to several advantageous characteristics compared to other raw materials. Its short production cycle and ability to thrive in adverse soil and climate conditions contribute to its appeal. Additionally, breeders seek genotypes with high productivity potential and adaptability to various favorable cultivation environments. This study aimed to estimate genetic parameters, predict genetic values using mixed models (REML/BLUP), and evaluate stability and adaptability for energy biomass production in elephant grass genotypes. The experiment was conducted in Campos dos Goytacazes, RJ, Brazil, utilizing a two-replicate experimental block design that included 40 elephant grass genotypes. Four harvest assessments were performed between 2016 and 2019. Genetic parameter estimation and selection of superior genotypes based on genetic value using the REML/BLUP procedure were performed using Selegen software. Stability and adaptability analyses were obtained through the harmonic mean of genotypic values (HMGV), enabling the identification of stable and highly productive genotypes. Genotypes 17, 18, 32, 16, 36, 6, 15, 31, and 34 exhibited outstanding performance in terms of HMGV, indicating enhanced stability, adaptability, and simultaneous productivity, thus ensuring robustness in cultivation. These selected genotypes hold potential for future breeding programs aimed at improving elephant grass yield for biomass production. secondgeneration second generation materials appeal Additionally environments parameters REML/BLUP, REMLBLUP , REML BLUP (REML/BLUP) Goytacazes RJ Brazil tworeplicate two replicate 4 201 2019 software HMGV (HMGV) 17 18 32 16 36 6 15 31 3 (REML/BLUP 20 (HMGV 1 2

Resumo O objetivo deste artigo é descrever o perfil epidemiológico e a distribuição espacial dos óbitos e casos confirmados da COVID-19 na macrorregião de saúde Oeste da Bahia. Estudo ecológico sobre a interiorização do SARS-CoV-2, entre 21 de março de 2020 e 31 de março de 2021, considerando o coeficiente de incidência e de mortalidade, letalidade, densidade de casos e média móvel de casos e óbitos. Foram registrados 37.036 casos e 536 óbitos confirmados. Dos casos, 94,5% estão recuperados e 4,0% ativos. O coeficiente de incidência foi 3.884,1/100 mil habitantes, o coeficiente de mortalidade, 56,2/100 mil habitantes, e a letalidade, 1,4%. Identificou-se a predominância de intensidade muito alta e alta da ocorrência da COVID-19 na macrorregião, com a média móvel evidenciando uma tendência de crescimento. Os achados descrevem alto risco de infecção e morte na macrorregião, além de apresentar uma tendência de crescimento dos casos acumulados, confirmando a interiorização da doença.

Abstract This article aims to describe the epidemiological profile and the spatial distribution of deaths and confirmed cases of COVID-19 in the health macroregion of Western Bahia. An ecological study on the inland expansion of SARS-CoV-2 was performed from March 21, 2020 to March 31, 2021 considering incidence and mortality rate, case fatality rate, case density and moving average of cases and deaths. 37,036 cases and 536 confirmed deaths were registered. Of all cases, 94.5% recovered and 4.0% remained active. The incidence rate was 3884.1/100,000 inhabitants, the mortality rate 56.2/100,000 inhabitants and the fatality rate was 1.4% A predominance of very high and high intensity of the occurrence of COVID-19 in the macroregion was identified and moving average revealed an increasing trend. Findings show a high risk of infection and death in the macroregion, in addition to a growing trend in accumulated cases, confirming the inland expansion of the disease.

Abstract Introduction: Heart transplantation (HTx) is the gold standard procedure for selected individuals with refractory heart failure. High-intensity interval training (HIIT) is safe and allows patients to exercise in high intensity for longer time when compared to moderate-intensity continuous training (MICT). The primary aim of this study was to perform a systematic review and meta-analysis about the effect of HIIT compared to MICT on exercise capacity, peak heart rate, and heart rate reserve in HTx recipients. Secondarily, we pooled data comparing MICT and no exercise training in these patients. Methods: This systematic review followed the standardization of the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement and the Cochrane Collaboration Handbook. We presented the treatment effects of HIIT on the outcomes of interest as mean difference (MD) and 95% confidence interval (CI). Meta-analysis was performed using the random-effects, generic inverse variance method. Results: HIIT improved peak oxygen consumption (peakVO2) (MD = 2.1; 95% CI 1.1, 3.1; P<0.0001), peak heart rate (MD = 3.4; 95% CI 0.8, 5.9; P=0.009), and heart rate reserve (MD = 4.8; 95% CI -0.05, 9.6; P=0.05) compared to MICT. Improvements on peakVO2 (MD = 3.5; 95% CI 2.3, 4.7; P<0.00001) and peak heart rate (MD = 5.6; 95% CI 1.6, 9.6; P=0.006) were found comparing HIIT and no exercise training. Conclusion: Current available evidence suggests that HIIT leads to improvements on peakVO2, peak heart rate, and heart rate reserve compared to MICT in HTx recipients. However, the superiority of HIIT should be tested in isocaloric protocols. Introduction (HTx failure Highintensity High (HIIT moderateintensity moderate . (MICT) metaanalysis meta analysis capacity recipients Secondarily Methods Metaanalyses Meta analyses Handbook MD 95 CI. (CI) Metaanalysis randomeffects, randomeffects random effects, random-effects method Results peakVO (peakVO2 2.1 21 2 1 11 1.1 3.1 31 3 P<0.0001, P00001 P P<0.0001 , 0 0001 P<0.0001) 3.4 34 4 08 8 0.8 5.9 59 5 9 P=0.009, P0009 P=0.009 009 P=0.009) 4.8 48 0.05, 005 05 -0.05 9.6 96 6 P=0.05 P005 3.5 35 23 2.3 4.7 47 7 P<0.00001 P000001 00001 5.6 56 16 1.6 P=0.006 P0006 006 Conclusion However protocols (MICT (CI (peakVO 2. 1. 3. P0000 P<0.000 000 0. 5. P000 P=0.00 00 4. 0.05 -0.0 9. P=0.0 P00 P<0.0000 P00000 0000 P<0.00 0.0 -0. P=0. P0 P<0.0 -0 P=0 P<0. - P= P<0 P<

Resumo Neste trabalho, um fotorreator contínuo foi projetado e montado, usando peças recicláveis e de baixo custo, para desenvolver tratamentos químicos, baseados em processos oxidativos avançados (AOP), de efluentes têxteis altamente coloridos por azo-compostos. A fim de avaliar a eficiência deste sistema reacional sustentável, foi investigada a performance de três tratamentos destrutivos (UV/H2O2, Fenton e foto-Fenton) sobre a remoção de cor de soluções aquosas do corante denominado Reactive Black 5 (RB5). O efeito da concentração de oxidante (H2O2) e da carga inicial de corante sobre a taxa de remoção de cor foi também analisado. Os resultados mostraram que, independentemente das condições operacionais iniciais, o processo foto-Fenton alcançou as taxas mais elevadas de degradação, especialmente quando a maior razão entre as concentrações do oxidante e do corante foi empregada ([H2O2]: [RB5] = 24.5 mg L-1: 25 mg L-1), com a completa remoção de cor em apenas 10 minutos de experimento. Usando-se as mesmas condições iniciais, os processos Fenton e UV/H2O2 foram também capazes de descolorir completamente o poluente têxtil, entretanto precisando de 25 minutos e 45 minutos de reação, respectivamente. O efeito do pH sobre a descoloração pelo processo foto-Fenton foi também investigado, mostrando a mesma elevada performance nos pHs 3 e 4. O perfil de degradação obtido no tratamento foto-Fenton foi devidamente modelado pela cinética de pseudo-primeira ordem. O fotorreator contínuo de baixo custo mostrou-se bastante útil na degradação do corante RB5, principalmente quando o processo foto-Fenton foi empregado.

Abstract In this work, a flow photoreactor was designed and set up using low-cost and recyclable parts to develop chemical treatments based on advanced oxidation processes (AOP) of highly colored textile wastewater. To evaluate this sustainable system´s efficiency, we investigated and compared the performance of three types of destructive methods (UV/H2O2, Fenton, and photo-Fenton) on the decolorization of aqueous solutions of Reactive Black 5 dye (RB5). We also analyzed the effect of the oxidant and dye concentrations on the rate of color removal in each one of the three methods. The results showed that, regardless of the initial operating conditions, the photo-Fenton process achieved the highest degradation rates, particularly when the highest ratio between the oxidant and dye concentrations was used ([H2O2]: [RB5] = 24.5 mg L-1: 25 mg L-1), leading to complete color removal within only 10 minutes of reaction. With the same initial condition, the Fenton and UV/H2O2 processes were also capable of removing the color entirely, even though they demanded more extended runs of 25 min. and 45 min., respectively. The effect of pH on the decolorization by the photo-Fenton process was also investigated, showing the same high performance at pHs 3 and 4. The degradation profile achieved by the photo-Fenton treatment was appropriately fitted by a pseudo-first-order kinetic. The non-expensive photoreactor proved to be quite useful for the degradation of the RB5, mainly when this azo dye underwent the photo-Fenton process.

Abstract Objective: To evaluate the reliability of HRVT and postexercise parasympathetic reactivation analysis after a submaximal exercise test in young women. Methods: Twenty-four young women [21.1 (20.1, 24.7) years; 21.4 (20.1, 23.1) kg/m2] underwent three incremental exercise tests on a treadmill on occasions separated by 48 h. R-R intervals were continuously recorded during the incremental tests and throughout 5 min of post-exercise active recovery for HRVT and parasympathetic reactivation analysis, respectively. HRVT was identified using two methods: a) the intensity where no significant reduction of SD1 HRV index was identified by visual inspection of the graphic (HRVTvisual), b) the first stage to present SD1 value < 3ms (HRVT3ms). Postexercise parasympathetic reactivation was assessed at each minute during five minutes of recovery using SD1 and r-MSSD indexes. Absolute and relative reliability were assessed using the coefficient of variation (CV) and the intraclass correlation coefficient (ICC), respectively. Results: Good (ICC = 0.81, CV = 17.3) and excellent (ICC = 0.90, CV = 4.6) reliability were observed for HRVT3ms and HRVTvisual, respectively. On the postexercise period, good reliability was observed for both SD1 (ICC = 0.82-89, CV = 22.1-28.9) and r-MSSD (ICC = 0.82-89, CV = 21.1-28.6), with a high correlation between indexes in all-time points of analysis (r = 0.96-0.99). Conclusions: HRVT may be reproducibly assessed in women, mainly when HRVTvisual is used for analysis. In addition, SD1 and r-MSSD provide reliable and redundant measures of postexercise parasympathetic reactivation.

Resumo O objetivo deste artigo é descrever o perfil epidemiológico e a distribuição espacial dos óbitos e casos confirmados da COVID-19 na macrorregião de saúde Oeste da Bahia. Estudo ecológico sobre a interiorização do SARS-CoV-2, entre 21 de março de 2020 e 31 de março de 2021, considerando o coeficiente de incidência e de mortalidade, letalidade, densidade de casos e média móvel de casos e óbitos. Foram registrados 37.036 casos e 536 óbitos confirmados. Dos casos, 94,5% estão recuperados e 4,0% ativos. O coeficiente de incidência foi 3.884,1/100 mil habitantes, o coeficiente de mortalidade, 56,2/100 mil habitantes, e a letalidade, 1,4%. Identificou-se a predominância de intensidade muito alta e alta da ocorrência da COVID-19 na macrorregião, com a média móvel evidenciando uma tendência de crescimento. Os achados descrevem alto risco de infecção e morte na macrorregião, além de apresentar uma tendência de crescimento dos casos acumulados, confirmando a interiorização da doença.

Abstract This article aims to describe the epidemiological profile and the spatial distribution of deaths and confirmed cases of COVID-19 in the health macroregion of Western Bahia. An ecological study on the inland expansion of SARS-CoV-2 was performed from March 21, 2020 to March 31, 2021 considering incidence and mortality rate, case fatality rate, case density and moving average of cases and deaths. 37,036 cases and 536 confirmed deaths were registered. Of all cases, 94.5% recovered and 4.0% remained active. The incidence rate was 3884.1/100,000 inhabitants, the mortality rate 56.2/100,000 inhabitants and the fatality rate was 1.4% A predominance of very high and high intensity of the occurrence of COVID-19 in the macroregion was identified and moving average revealed an increasing trend. Findings show a high risk of infection and death in the macroregion, in addition to a growing trend in accumulated cases, confirming the inland expansion of the disease.

RESUMO Introdução: Os intervalos com atividade ou as intervenções com programas de exercícios na escola estão relacionados com a melhora da função cognitiva em adolescentes. Contudo, poucos estudos avaliaram a relação entre exercício físico e cognição em escolas de zonas rurais, onde os níveis de evasão são altos e o rendimento acadêmico é baixo. Objetivo: Analisar os efeitos de uma aula de exercício físico (EF) sobre o desempenho acadêmico subsequente dos alunos e o que sentem durante os testes de matemática (MAT) e de língua portuguesa (PO). Métodos: Trinta e seis estudantes (14,9 ± 1,5 anos) foram divididos randomicamente em dois grupos: um com 30 minutos de EF realizados a 74,3 ± 11,8% da FCmáx e um controle (CON), que permaneceram sentados assistindo a um filme antes dos testes (EF-MAT; EF-PO; CON-MAT; CON-PO). Resultados: O EF-MAT apresentou maior escore (5,3 ± 2,2) que o CON-MAT (4,0 ± 2,2). Os testes foram concluídos mais rapidamente no EF-PO (7,8 ± 3,3) do que no CON-PO (10,5 ± 4,2). O número de respostas corretas por minuto foi maior no EF-MAT e no EF-PO (0,52 ± 0,25; 0,64 ± 0,51) do que no CON-MAT e no CON-PO (0,35 ± 0,19; 0,41 ± 0,41). Além disso, 38,9% do EF-MAT sentiram que estavam mais concentrados durante o teste, em comparação com apenas 16,7% do CON-MAT que se sentiram mais concentrados. Durante o a prova de português, 27,8% dos CON-PO reclamaram de maior apreensão quando comparados com 8,3% do EF-PO. Ainda, 36,1% relataram cansaço durante o teste de PO depois de EF, comparados com 8,3% do grupo CON-PO. Conclusão: A aula de EF melhorou o desempenho acadêmico dos adolescentes. Apesar da sensação de cansaço, mais estudantes sentiram menos apreensão e estavam mais concentrados durante os testes depois de EF. Nível de evidência I; Estudos de acurácia diagnóstica (STARD).

ABSTRACT Introduction: Activity breaks or physical exercise interventions in schools are linked to better cognitive function in adolescents. However, few studies have evaluated the relationship between physical exercise and cognition in rural schools, where drop-out levels tend to be higher and academic achievement lower. Objective: To analyze the effects of a physical exercise class (PE) on subsequent academic performance of students, and how they felt during mathematics (MATH) and Portuguese language (PL) tests. Methods: Thirty-six students (14.9 ± 1.5 years) randomly carried out 30 min of PE, performed at 74.3 ± 11.8%HRmax, while a control group (CON) remained seated watching a movie, prior to the tests (PE-MATH; PE-PL; CON-MATH; CON-PL). Results: The PE-MATH group presented higher scores (5.3 ± 2.2) than the CON-MATH group (4.0 ± 2.2). The tests were completed more quickly in PE-PL (7.8 ± 3.3 minutes) than in CON-PL (10.5 ± 4.2 minutes). The number of correct answer per minute was higher in PE-MATH and PE-PL (0.52 ± 0.25; 0.64 ± 0.51) than in CON-MATH and CON-PL (0.35 ± 0.19; 0.41 ± 0.41). Furthermore, 38.9% of PE-MATH felt more focused during the test, while only 16.7% of CON-MATH felt more focused. During the Portuguese language test, 27.8% of CON-PL complained of greater apprehensiveness, compared to 8.3% for PE-PL. Also, 36.1% reported feeling fatigued during PL after PE, compared to 8.3% in the CON-PL group. Conclusions: PE improved the adolescents' academic performance. Despite feeling fatigue, more students who performed physical exercise felt less apprehensive and more focused during the tests after PE. Level of evidence I; STARD: studies of diagnostic accuracy.

RESUMEN Introducción: Los intervalos con actividad o las intervenciones con programas de ejercicios en la escuela están relacionados con la mejora de la función cognitiva en adolescentes. Sin embargo, pocos estudios evaluaron la relación entre ejercicio físico y cognición en escuelas de zonas rurales, en donde los niveles de evasión son altos y el rendimiento académico es bajo. Objetivo: Analizar los efectos de una clase de ejercicio físico (EF) sobre el desempeño académico subsiguiente de los alumnos y lo que sienten durante los tests de matemática (MAT) y de idioma portugués (PO). Métodos: Treinta y seis estudiantes (14,9 ± 1,5 años) fueron divididos aleatoriamente en dos grupos: uno con 30 minutos de EF realizados a 74,3 ± 11,8% de la FCmáx y un control (CON), que permanecieron sentados viendo una película antes de los tests (EF-MAT; EF-PO; CON-MAT; CON-PO). Resultados: El EF-MAT presentó mayor puntuación (5,3 ± 2,2) que el CON-MAT (4,0 ± 2,2). Los tests fueron concluidos más rápidamente en el EF-PO (7,8 ± 3,3) que en el CON-PO (10,5 ± 4,2). El número de respuestas correctas por minuto fue mayor en el EF-MAT y en el EF-PO (0,52 ± 0,25,0,64 ± 0,51) que en el CON-MAT y en el CON-PO (0,35 ± 0,19, 0,41 ± 0,41). Además, 38,9% del EF-MAT sintió que estaba más concentrado durante el test, en comparación con sólo 16,7% del CON-MAT que se sintió más concentrado. Durante la prueba de portugués, 27,8% de los CON-PO reclamó de mayor aprehensión cuando comparado con 8,3% del EF-PO. Además, 36,1% relató cansancio durante el test de PO después del EF, comparado con el 8,3% del grupo CON-PO. Conclusión: La clase de EF mejoró el desempeño académico de los adolescentes. A pesar de la sensación de cansancio, más estudiantes sintieron menos aprehensión y estaban más concentrados durante los tests después de EF. Nivel de evidencia I; Estudios de precisión diagnóstica (STARD).

In this paper, we have applied state-of-the-art technologies and new investigations were developed focusing on obtaining simple and inexpensive molecules for treating cardiovascular diseases, as they are considered the leading cause of death in the world. For the first time, the inclusion complex of sulcatone (SU) and β-cyclodextrin (β-CD) was achieved (using a spray drier) and characterized making use of spectroscopic, thermal and computational methods. In addition, the system was evaluated regarding its vasorelaxant properties. Evidence of the inclusion complex formation was provided using different techniques, such as X-ray diffraction (XRD), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), Fourier transform infrared (FTIR), and 1H nuclear magnetic resonance (NMR) spectroscopies and then deduced by pharmacological experiments, which showed significant changes in relation to the initial material.

ABSTRACT Objective: To know the repercussions of the experience of family violence from the oral history of adolescents. Method: Qualitative study based on the Oral History method, conducted from interviews with adolescents enrolled in a public school in Salvador, State of Bahia, Brazil. The data were systematized according to the thematic analysis and supported by theoretical references on family violence and adolescence. Results: Family violence implies physical illness associated with the damage caused by physical aggression and somatization of violent events, as well as compromising mental health, provoking feelings of deep sadness, self-injury behavior and suicidal ideation. All of these factors impair interpersonal relationships, school performance, as well as making them more vulnerable to alcohol intake. Final Considerations: The study indicates signs suggestive of grievance, from which the professionals should proceed the investigation in order to refute or confirm the experience of the phenomenon, as well as intervene in the cases.

RESUMEN Objetivo: Conocer las repercusiones derivadas de la violencia intrafamiliar a partir de historias orales de adolescentes. Método: Se trata de una investigación cualitativa basada en el método de la Historia Oral, realizada mediante entrevistas a alumnos adolescentes de una escuela pública de Salvador, Bahía, Brasil. Se sistematizaron los datos según el análisis temático con respaldo en referenciales teóricos sobre violencia intrafamiliar y adolescencia. Resultados: La violencia intrafamiliar trae como consecuencia enfermedades asociadas a la agresión física padecida, somatizando el penoso evento y comprometiendo la salud mental, ya que suscita sentimientos de profunda tristeza, comportamiento de autolesión e ideas suicidas. Todos estos factores perjudican las relaciones interpersonales, el rendimiento escolar y propician el uso del alcohol. Consideraciones Finales: El estudio señala la existencia del agravio, a partir del cual los profesionales deben realizar investigaciones en el sentido de refutar o confirmar la vivencia del fenómeno e intervenir en los casos.

RESUMO Objetivo: Conhecer as repercussões da vivência de violência intrafamiliar a partir da história oral de adolescentes. Método: Pesquisa qualitativa, fundamentada no método da História Oral, realizada a partir de entrevistas com adolescentes matriculadas(os) em uma escola pública de Salvador, Bahia, Brasil. Os dados foram sistematizados conforme a análise temática e respaldados em referenciais teóricos sobre violência intrafamiliar e adolescência. Resultados: A violência intrafamiliar implica adoecimento físico associado aos danos decorrentes da agressão física e à somatização do evento violento, bem como compromete a saúde mental, suscitando sentimentos de tristeza profunda, comportamento de autolesão e ideação suicida. Todos esses fatores prejudicam as relações interpessoais, o desempenho escolar, bem como vulnerabiliza para o uso de álcool. Considerações Finais: O estudo aponta sinais sugestivos do agravo, a partir dos quais os profissionais deverão proceder a investigação no sentido de refutar ou confirmar a vivência do fenômeno, bem como intervir diante dos casos.

RESUMO Objetivo: Conhecer as repercussões da vivência de violência intrafamiliar a partir da história oral de adolescentes. Método: Pesquisa qualitativa, fundamentada no método da História Oral, realizada a partir de entrevistas com adolescentes matriculadas(os) em uma escola pública de Salvador, Bahia, Brasil. Os dados foram sistematizados conforme a análise temática e respaldados em referenciais teóricos sobre violência intrafamiliar e adolescência. Resultados: A violência intrafamiliar implica adoecimento físico associado aos danos decorrentes da agressão física e à somatização do evento violento, bem como compromete a saúde mental, suscitando sentimentos de tristeza profunda, comportamento de autolesão e ideação suicida. Todos esses fatores prejudicam as relações interpessoais, o desempenho escolar, bem como vulnerabiliza para o uso de álcool. Considerações Finais: O estudo aponta sinais sugestivos do agravo, a partir dos quais os profissionais deverão proceder a investigação no sentido de refutar ou confirmar a vivência do fenômeno, bem como intervir diante dos casos.

ABSTRACT Objective: To know the repercussions of the experience of family violence from the oral history of adolescents. Method: Qualitative study based on the Oral History method, conducted from interviews with adolescents enrolled in a public school in Salvador, State of Bahia, Brazil. The data were systematized according to the thematic analysis and supported by theoretical references on family violence and adolescence. Results: Family violence implies physical illness associated with the damage caused by physical aggression and somatization of violent events, as well as compromising mental health, provoking feelings of deep sadness, self-injury behavior and suicidal ideation. All of these factors impair interpersonal relationships, school performance, as well as making them more vulnerable to alcohol intake. Final Considerations: The study indicates signs suggestive of grievance, from which the professionals should proceed the investigation in order to refute or confirm the experience of the phenomenon, as well as intervene in the cases.

RESUMEN Objetivo: Conocer las repercusiones derivadas de la violencia intrafamiliar a partir de historias orales de adolescentes. Método: Se trata de una investigación cualitativa basada en el método de la Historia Oral, realizada mediante entrevistas a alumnos adolescentes de una escuela pública de Salvador, Bahía, Brasil. Se sistematizaron los datos según el análisis temático con respaldo en referenciales teóricos sobre violencia intrafamiliar y adolescencia. Resultados: La violencia intrafamiliar trae como consecuencia enfermedades asociadas a la agresión física padecida, somatizando el penoso evento y comprometiendo la salud mental, ya que suscita sentimientos de profunda tristeza, comportamiento de autolesión e ideas suicidas. Todos estos factores perjudican las relaciones interpersonales, el rendimiento escolar y propician el uso del alcohol. Consideraciones Finales: El estudio señala la existencia del agravio, a partir del cual los profesionales deben realizar investigaciones en el sentido de refutar o confirmar la vivencia del fenómeno e intervenir en los casos.