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au:Salgado, Paula Rodrigues

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Antimicrobial Orthodontic Wires Coated with Silver Nanoparticles
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Gonçalves, Isabella Salgado

; Viale, Ana Beatriz

; Sormani, Natália Navarro

; Pizzol, Karina Eiras Dela Coleta

; Araujo-Nobre, Alyne Rodrigues de

; Oliveira, Paula Chagas Silva de

; Barud, Hélida Gomes de Oliveira

; Antonio, Selma Gutierrez

; Barud, Hernane da Silva

Brazilian Archives of Biology and Technology

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2020, Volume 63 elocation e20190339

Abstract: En | Text: En | PDF: En

Abstract Conventional orthodontic treatment with the use of stainless steel may be detrimental to oral health by promoting demineralizing lesions appearance and increasing adhesion and formation of bacterial biofilm, inducing the development of cavities. An alternative that has been researched to reduce the side effects of orthodontic treatment is the coating of materials with antimicrobial nanoparticles. Nanometric- sized particles increase their surface area and contact with the microbial membrane, consequently intensifying their bacteriostatic and bactericidal effect. In this work, hydrothermal synthesis, a “green” process was used to attach silver nanoparticles (AgNPs) to the surface of two different brands of orthodontic wires. The coated materials were analyzed for their physicochemical properties by scanning electron microscopy (SEM), X-ray diffraction (XRD) and differential scanning calorimetry (DSC), which showed the distribution of AgNPs along the wires without modifying their properties. In the microbiological test, one of the brands showed a statistically significant difference in microbial adhesion and biofilm formation by Staphylococcus aureus and Streptococcus mutans. Results lead to the conclusion that antimicrobial orthodontic wires coated with silver nanoparticles through hydrothermal synthesis is a promising material for the improvement of orthodontic treatment.

https://doi.org/10.1590/1678-4324-2020190339 652 downloads

Atualização da Diretriz Brasileira de Dislipidemias e Prevenção da Aterosclerose – 2017
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Faludi, André Arpad

; Izar, Maria Cristina de Oliveira

; Saraiva, José Francisco Kerr

; Chacra, Ana Paula Marte

; Bianco, Henrique Tria

; Afiune Neto, Abrahão

; Bertolami, Adriana

; Pereira, Alexandre C.

; Lottenberg, Ana Maria

; Sposito, Andrei C.

; Chagas, Antonio Carlos Palandri

; Casella Filho, Antonio

; Simão, Antônio Felipe

; Alencar Filho, Aristóteles Comte de

; Caramelli, Bruno

; Magalhães, Carlos Costa

; Negrão, Carlos Eduardo

; Ferreira, Carlos Eduardo dos Santos

; Scherr, Carlos

; Feio, Claudine Maria Alves

; Kovacs, Cristiane

; Araújo, Daniel Branco de

; Magnoni, Daniel

; Calderaro, Daniela

; Gualandro, Danielle Menosi

; Mello Junior, Edgard Pessoa de

; Alexandre, Elizabeth Regina Giunco

; Sato, Emília Inoue

; Moriguchi, Emilio Hideyuki

; Rached, Fabiana Hanna

; Santos, Fábio César dos

; Cesena, Fernando Henpin Yue

; Fonseca, Francisco Antonio Helfenstein

; Fonseca, Henrique Andrade Rodrigues da

; Xavier, Hermes Toros

; Mota, Isabela Cardoso Pimentel

; Giuliano, Isabela de Carlos Back

; Issa, Jaqueline Scholz

; Diament, Jayme

; Pesquero, João Bosco

; Santos, José Ernesto dos

; Faria Neto, José Rocha

; Melo Filho, José Xavier de

; Kato, Juliana Tieko

; Torres, Kerginaldo Paulo

; Bertolami, Marcelo Chiara

; Assad, Marcelo Heitor Vieira

; Miname, Márcio Hiroshi

; Scartezini, Marileia

; Forti, Neusa Assumpta

; Coelho, Otávio Rizzi

; Maranhão, Raul Cavalcante

; Santos Filho, Raul Dias dos

; Alves, Renato Jorge

; Cassani, Roberta Lara

; Betti, Roberto Tadeu Barcellos

; Carvalho, Tales de

; Martinez, Tânia Leme da Rocha

; Giraldez, Viviane Zorzanelli Rocha

; Salgado Filho, Wilson

Arquivos Brasileiros de Cardiologia

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aug 2017, Volume 109 N. 2 Pages 1 - 76

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.5935/abc.20170121 199102 downloads

Antinociceptive activity of Sargassum polyceratium and the isolation of its chemical components
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Santos, Aline Kely Felício de Sousa

; Fonseca, Diogo Vilar da

; Salgado, Paula Regina Rodrigues

; Muniz, Vanessa Morais

; Torres, Paula de Arruda

; Lira, Narlize Silva

; Dias, Celidarque da Silva

; Pordeus, Liana Clébia de Morais

; Barbosa-Filho, José Maria

; Almeida, Reinaldo Nobrega de

Revista Brasileira de Farmacognosia

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dec 2015, Volume 25 N. 6 Pages 683 - 689

Abstract: En | Text: En | PDF: En

Abstract Marine algae have been the focus of important studies over the past fifty years, with a considerable number of components important to chemists and taxonomists having been isolated and characterized. The scientific data available on Sargassum polyceratium are extremely limited. The objective of the present study was to evaluate the antinociceptive activity of an ethanol extract of S. polyceratium and to isolate its components. Intraperitoneal treatment with ethanol extract of S. polyceratium reduced the number of acetic acid-induced writhes and the amount of time spent in paw-licking in the second phase of the formalin test. Ethanol extract of S. polyceratium also reduced the amount of time spent in paw-licking in the glutamate test; however, there was no difference in the reaction time in the hot plate test at any of the doses tested. The chemical components isolated from ethanol extract of S. polyceratium were identified using one- and two-dimensional spectroscopic methods such as infrared spectroscopy, mass spectrometry and 1H and 13C nuclear magnetic resonance spectroscopy. The analytical results were also compared with data obtained in the literature. The following porphyrin derivatives were isolated from S. polyceratium: 132-hydroxy-(132-R)-pheophytin-a, 132-hydroxy-(132-S)-pheophytin-a, pheophytin-a, and the steroid fucosterol. The present results indicate that the ethanol extract of S. polyceratium has antinociceptive activity. In addition, four new substances were isolated from the species evaluated.

https://doi.org/10.1016/j.bjp.2015.07.017 1164 downloads

Opções a capsulotomia e capsulectomia no tratamento da contratura capsular: existem alternativas medicamentosas ao tratamento cirúrgico? Revisão de literatura capsular cirúrgico
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OLIVEIRA, KLEITON CARDOZO DE

; PEREIRA, RUI MANOEL RODRIGUES

; SALGADO, IVO VIEIRA

; BAPTISTA, EDUARDO VICTOR DE PAULA

; ARANTES, GUILHERME CAMPELO

; LUNA, IGOR CHAVES

Revista Brasileira de Cirurgia Plástica

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mar 2015, Volume 30 N. 1 Pages 123 - 128

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: A contratura capsular é uma das principais complicações em cirurgias envolvendo implantes mamários. A classificação mais usada para avaliar o grau de contratura é a de Baker, que a divide em graus I, II, III e IV, sendo as de grau III e IV consideradas significativas. Apesar de existirem diversas teorias, a etiologia da contratura capsular permanece incerta. O tratamento convencional para os casos de contratura é a abordagem cirúrgica com realização de capsulotomia ou capsulectomia. Estes procedimentos, no entanto, não estão isentos de morbidades, com complicações como deiscências, hematomas, seromas, pneumotórax, assimetrias e recidiva da contratura. Este estudo faz uma revisão sobre as alternativas ao tratamento cirúrgico convencional, descritas na literatura. Métodos: Foi realizada pesquisa nas bibliotecas da Pubmed e da Cochrane, utilizando-se os termos: ‘capsular contracture’, ‘capsular contracture treatment’ e ‘capsular contracture breast treatment’. Foram identificados 991 artigos e selecionados os que discutiam opções medicamentosas para o tratamento de contratura, diferentes de capsulectomia e capsulotomia. Resultados: Foram encontrados vårios estudos utilizando drogas com o fim de reduzir a contratura capsular, das quais o Zafirlucaste é apresentado em maior número de trabalhos. Conclusão: Dentre as várias drogas utilizadas, o Zafirlucaste apresentou boa eficácia, com baixos índices de complicação; a Triancinolona parece ser também uma boa opção, no entanto precisa de profissional habilitado para realizar as infiltrações. As demais drogas necessitam de maiores estudos. Introdução mamários Baker I II significativas teorias incerta procedimentos morbidades deiscências hematomas seromas pneumotórax literatura Métodos Cochrane utilizandose se termos contracture, , contracture’ treatment treatment. . 99 Resultados trabalhos Conclusão utilizadas eficácia complicação opção infiltrações 9

ABSTRACT Introduction: Capsular contracture is among the main complications of surgeries involving breast implants. The most commonly used classification to assess the degree of contracture is the Baker grading system, which divides contractures into grades I, II, III, and IV. Of these, grade III and IV contractures are considered significant. Although several causes have been postulated, the etiology of capsular contracture remains uncertain. Conventional treatment for contracture is based on a surgical approach, specifically capsulotomy or capsulectomy. These procedures, however, are not exempt from morbidity, and patients may develop complications such as dehiscence, hematoma, seroma, pneumothorax, asymmetry, and contracture recurrence. This study provides a review of alternatives to conventional surgery described in the literature. Methods: We researched the PubMed and Cochrane Library databases using the following keywords: “capsular contracture”, “capsular contracture treatment”, and “capsular contracture breast treatment”. We identified 991 articles from which we selected those discussing medication options for contracture treatment other than capsulectomy and capsulotomy. Results: We identified several studies in which drugs, most commonly zafirlukast, were used to reduce capsular contracture. Conclusion: Among the various reported drugs, zafirlukast exhibited good efficacy and a low rate of complication. Triamcinolone also appears to be a good option, although professional assistance would be needed for drug administration via infiltration. The other drugs described would require further investigation. Introduction implants system I II these significant postulated uncertain approach procedures however morbidity dehiscence hematoma seroma pneumothorax asymmetry recurrence literature Methods keywords contracture, , contracture” treatment, treatment” treatment. . 99 Results Conclusion complication option infiltration investigation 9

https://doi.org/10.5935/2177-1235.2015rbcp0127

Mycobacterium marinum infection: a case report
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Sette, Christiane Salgado

; Wachholz, Patrick Alexander

; Masuda, Paula Yoshiko

; Figueira, Renata Borges Fortes da Costa

; Mattar, Fernanda Rodrigues de Oliveira

; Ura, Deise Godoy

Journal of Venomous Animals and Toxins including Tropical Diseases

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2015, Volume 21 Pages 1 - 5

Abstract: En | Text: En | PDF: En

AbstractThe infection by Mycobacterium marinum in humans is relatively uncommon. When it occurs, it mainly affects the skin, usually with a chronic, indolent and benign evolution. The diagnosis requires a high index of suspicion, and a significant delay may be observed between the first symptoms to the final diagnosis. This present case reports a M. marinum infection in an immunocompetent patient that had a chronic undiagnosed injury on the dominant hand for at least five years. The patient had several medical consultations, without proper suspicion, hampering adequate diagnostic investigation. Histopathology detected tuberculoid granulomas, but showed no acid-fast bacilli. The culture in appropriate medium and the polymerase chain reaction-restriction enzyme analysis (PRA)-hsp65 confirmed the diagnosis. Treatment with clarithromycin (1 g/day) for three months was effective. Although uncommon, this infection is a contact zoonosis. Therefore, it is important for clinicians to be aware of this diagnosis and properly guide preventable measures to professionals that are in risk group.

https://doi.org/10.1186/s40409-015-0008-9 4572 downloads

Short-term changes in handgrip strength, body composition, and lymphedema induced by breast cancer surgery
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Gomes, Patricia Rodrigues Lourenço

; Freitas Junior, Ismael Forte

; Silva, Camila Buonani da

; Gomes, Igor Conterato

; Rocha, Ana Paula Rodrigues

; Salgado, Afonso Shiguemi Inoue

; Carmo, Edna Maria do

Revista Brasileira de Ginecologia e Obstetrícia

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jun 2014, Volume 36 N. 6 Pages 244 - 250

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

OBJETIVO: Este estudo investigou alterações de curto prazo na composição corporal, na força de preensão palmar e na presença de linfedema em mulheres submetidas à cirurgia do câncer de mama. MÉTODOS: Noventa e cinco mulheres participaram de um estudo transversal, sendo divididas em dois grupos: Controle (n=46), mulheres saudáveis, e Experimental (n=49), mulheres seis meses após cirurgia do câncer de mama. O Grupo Experimental foi subdividido em mastectomia total direita (RTM, n=15), mastectomia total esquerda (LTM, n=11), quadrantectomia direita (RQ, n=13) e quadrantectomia esquerda (LQ, n=10). Também foi redistribuído entre mulheres com presença (n=10) ou ausência (n=39) de linfedema. Foram avaliadas a presença de linfedema, a força de preensão palmar e a composição corporal. RESULTADOS: A massa magra de tronco e a força de preensão palmar estavam diminuídas no Grupo Experimental. Massa magra total estava aumentada na LTM comparada à RTM ou LQ. Força de preensão palmar esquerda na LTM estava diminuída comparada à RTM e RQ e em LQ comparada à RTM e RQ. Finalmente, massa magra total, magra e gorda de tronco e massa magra de braço esquerdo e direito estavam aumentadas em mulheres com linfedema. CONCLUSÕES: Sobreviventes do câncer de mama possuem alterações na composição corporal e na força de preensão palmar seis meses após a cirurgia, porém a interação entre o tipo de cirurgia e seu impacto não está clara. Além disso, mulheres que desenvolveram linfedema neste período mostraram alterações mais significantes na composição corporal, mas que não foram suficientes para causar prejuízo na força de preensão palmar.

PURPOSE: This study investigated short-term changes in body composition, handgrip strength, and presence of lymphedema in women who underwent breast cancer surgery. METHODS: Ninety-five women participated in a cross-sectional study, divided into two groups: Control (n=46), with healthy women, and Experimental (n=49), with women six months after breast cancer surgery . The Experimental Group was subdivided into right total mastectomy (RTM, n=15), left total mastectomy (LTM, n=11), right quadrant (RQ, n=13), and left quadrant (LQ, n=10). It was also redistributed among women with presence (n=10) or absence (n=39) of lymphedema. Presence of lymphedema, handgrip strength, and body composition were assessed. RESULTS: Trunk lean mass and handgrip strength were decreased in the Experimental Group. Total lean mass was increased in the LTM compared to RTM or LQ. Left handgrip strength in LTM was decreased compared to RTM and RQ and in LQ compared to RTM and RQ. Finally, total lean mass, trunk fat mass, trunk lean mass, right and left arm lean mass were increased in women with lymphedema. CONCLUSIONS: Breast cancer survivors have changes in their body composition and in handgrip strength six months after surgery; however, the interaction between the type of surgery and its impact is unclear. Furthermore, women who developed lymphedema in this period showed more significant changes in the body composition, but they were not enough to cause impairment in handgrip strength.

https://doi.org/10.1590/S0100-720320140005004 3924 downloads

Total phenol concentrations in coffee tree leaves during fruit development
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Salgado, Paula Rodrigues

; Favarin, José Laércio

; Leandro, Roseli Aparecida

; Lima Filho, Oscar Fontão de

Scientia Agricola

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2008, Volume 65 N. 4 Pages 354 - 359

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Os vegetais apresentam defesa natural contra fatores externos, por meio da síntese de fenóis, as quais variam com as fases fenológicas e com o clima. Os teores de fenóis totais foram extraídos das folhas fonte e dreno e analisados em relação à produção de café, fenologia e clima. As variáveis climáticas consideradas foram: temperatura, radiação e insolação. Realizaram-se avaliações de altura, diâmetro e comprimento de ramos para determinar as taxas de crescimento. As quantidades de fenóis determinadas nas plantas com produção (174,0 mg g-1 e 138,9 mg g-1 - nova e madura) e sem produção (186,5 mg g-1 e 127,6 mg g-1 - nova e madura) não variaram. No entanto, a concentração de fenóis nas folhas nova das plantas com e sem produção foi maior que a quantidade determinada nas folhas madura, da ordem de 25% e 46%, respectivamente. A síntese de fenóis na granação (146,8 mg g-1) foi 31% inferior em relação às quantidades determinadas na maturação (212,4 mg g-1). A metabolização de fenóis depende, indiretamente, da temperatura e da radiação global. A orientação do manejo deve levar em consideração as épocas de comprometimento da defesa natural, em relação à produção de fenóis.

Vegetables have a natural defense against external factors synthesizing phenolic compounds, which depends on the maturity stage and on the climate. Total phenol grades were extracted from mature and young coffee leaves and were analyzed in relation to yield, phenology and climate. The climatic conditions were described by air temperature, global radiation and daily insolation. Evaluations were made on height, diameter and length of reproductive branches to determine the respective vegetative growth rates of the plants. The amounts of total phenols in the plants at the production stage was 174.0 mg g-1 and 138.9 mg g-1 for young and mature leaves, respectively, and for plants without fruit formation 186.5 mg g-1 and 127.6 mg g-1 for young and mature leaves, respectively. The total phenol concentrations in young leaves with and without fruit formation were 25% and 46% greater compared to mature leaves. The secondary phenol synthesis in seed (146.8 mg g-1) was 31% lower than during grain maturation (212.4 mg g-1). The total phenol metabolization depends indirectly on the temperature and on the global radiation, presenting an inverse trend in relation to these climatic variables. Crop protection management should take into consideration periods of endanger of this natural defense of the plant.

4787 downloads Cited 3 times in SciELO

Teor de zinco no café como variável da disponibilidade no solo e extrator
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Favarin, José Laércio

; Vitti, Godofredo Cesar

; Dourado Neto, Durval

; Favarin Junior, José Laércio

; Salgado, Paula Rodrigues

Revista Brasileira de Ciência do Solo

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oct 2007, Volume 31 N. 5 Pages 1191 - 1196

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

No Brasil são cultivadas duas espécies de café: Coffea arabica L. e Coffea canephora Pierre. As pesquisas com adubação com Zn têm sido feitas, principalmente, com cultivares arábica. Esta pesquisa foi realizada com objetivo de obter a relação entre os teores de Zn disponível pelos extratores DTPA e Mehlich-1 em plantas de C. arabica cv. Mundo Novo IAC 379-19 (MN) e C. canephora cv. Apoatã IAC 2258 (AP), bem como em plantas enxertadas (MN/AP). Os tratamentos foram obtidos pelo fatorial 3 x 3, entre materiais genéticos (MN, AP e MN/AP) e doses de Zn (0, 10 e 20 mg dm-3). O teor de Zn na planta, em relação à disponibilidade do nutriente no solo, independentemente dos extratores, varia com a espécie e a combinação entre espécies e a enxertia. Os extratores DTPA e Mehlich-1 apresentaram eficiência semelhante para determinar o teor de Zn disponível no solo, independentemente da espécie (C. arabica e C. canephora). A absorção máxima de Zn ocorreu com teor disponível de 5,6 mg dm-3 (DTPA) e 6,6 mg dm-3 (Mehlich-1) para a cultivar Mundo Novo (C. arabica). Para a espécie C. canephora cv. Apoatã e nas plantas enxertadas (MN/AP), não foi estabelecida a máxima absorção de Zn, independentemente dos extratores, nas doses utilizadas no experimento.

Two species of coffee (Coffea arabica L. and Coffea canephora Pierre) are cultivated in Brazil, but most research on Zn fertilization to date has focused on C. arabica. This study was carried out to determine the functional relationship between soil Zn availability determined by DTPA and Mehlich-1 extractors and Zn content in coffee plants belonging to the species C. arabica, cv. Mundo Novo IAC 379-19 (MN) and C. canephora, cv. Apoatã IAC 2258 (AP), as well as grafted plants (MN/AP). The treatments were a 3 x 3 factorial combination of cultivars (MN, AP and MN/AP) and Zn doses (0, 10 and 20 mg dm-3). The plant Zn content, in relation to soil Zn availability, does not depend on the extractant, but varies with the coffee species or grafted species combination. The DTPA and Mehlich-1 extractants were similarly efficient to quantify the soil Zn availability, independent of the coffee species (C. arabica and C. canephora). Zn uptake peaked at soil Zn contents of 5.6 mg dm-3 (DTPA) and 6.6 mg dm-3 (Mehlich-1) for Mundo Novo (C. arabica) cultivar. Based on the Zn doses employed in the present study, the maximum Zn uptake of C. canephora (cv. Apoatã) and grafted plants (MN/AP) could not be determined, independently of the soil extractants.

1918 downloads Cited 4 times in SciELO

IV Diretriz Brasileira sobre Dislipidemias e Prevenção da Aterosclerose: Departamento de Aterosclerose da Sociedade Brasileira de Cardiologia
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Sposito, Andrei C.

; Caramelli, Bruno

; Fonseca, Francisco A. H.

; Bertolami, Marcelo C.

; Afiune Neto, Abrahão

; Souza, Aguinaldo David

; Lottenberg, Ana Maria Pitta

; Chacra, Ana Paula

; Faludi, André A.

; Loures-Vale, Andréia A.

; Carvalho, Antônio Carlos

; Duncan, Bruce

; Gelonese, Bruno

; Polanczyk, Carisi

; Rodrigues Sobrinho, Carlos Roberto M.

; Scherr, Carlos

; Karla, Cynthia

; Armaganijan, Dikran

; Moriguchi, Emílio

; Saraiva, Francisco

; Pichetti, Geraldo

; Xavier, Hermes Toros

; Chaves, Hilton

; Borges, Jairo Lins

; Diament, Jayme

; Guimarães, Jorge Ilha

; Nicolau, José Carlos

; Santos, José Ernesto dos

; Lima, José Jayme Galvão de

; Vieira, José Luiz

; Novazzi, José Paulo

; Faria Neto, José Rocha

; Torres, Kerginaldo P.

; Pinto, Leonor de Almeida

; Bricarello, Liliana

; Bodanese, Luiz Carlos

; Introcaso, Luiz

; Malachias, Marcus Vinícius Bolívar

; Izar, Maria Cristina

; Magalhães, Maria Eliane C.

; Schmidt, Maria Inês

; Scartezini, Mariléia

; Nobre, Moacir

; Foppa, Murilo

; Forti, Neusa A.

; Berwanger, Otávio

; Gebara, Otávio C. E.

; Coelho, Otávio Rizzi

; Maranhão, Raul C.

; Santos Fº, Raul Dias dos

; Costa, Rosana Perim

; Barreto, Sandhi

; Kaiser, Sérgio

; Ihara, Silvia

; Carvalho, Tales de

; Martinez, Tania Leme Rocha

; Relvas, Waldir Gabriel Miranda

; Salgado, Wilson

Arquivos Brasileiros de Cardiologia

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apr 2007, Volume 88 Pages 2 - 19

Abstract: Pt | Text: Pt | PDF: Pt

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You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.

For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

See below the complete list of search indexes that can be used:

Index code	Element
ti	article title
au	author
kw	article keywords
subject	subject (title words, abstract and keywords)
ab	abstract
ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

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