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RESUMO Objetivo Analisar a cobertura vacinal contra sarampo, caxumba e rubéola em crianças até 24 meses de idade e os fatores associados à não vacinação em coorte de nascidos-vivos em 2017-2018, em capitais e municípios de grande porte populacional do interior do Nordeste brasileiro. Métodos Inquérito domiciliar populacional com análise de cobertura vacinal e fatores sociodemográficos por regressão logística. Resultados Em 12.137 crianças, cobertura vacinal de 79,3% (IC95% 76,5;81,8) e taxa de abandono de 10,6%. Associação à não vacinação: estrato socioeconômico A (OR-a 1,29; IC95% 1,10;1,50), residir no interior (OR-a 1,22; IC95% 1,07;1,39), não acesso ao Programa Bolsa Família (OR-a 1,19; IC95% 1,05;1,34), renda familiar ≤ R$ 1.000,00 (OR-a 1,17; IC95% 1,03;1,31), mãe sem trabalho remunerado (OR-a 1,28; IC95% 1,15;1,42), > 1 filho por mãe (OR-a 1,12; IC95% 1,08;1,17), sem caderneta de vacinação (OR-a 10,69; IC95% 6,27;18,20). Conclusão Baixa cobertura e alta taxa de abandono vacinal em capitais e municípios do interior do Nordeste. sarampo 2 nascidosvivos nascidos vivos 20172018, 20172018 2017 2018, 2018 2017-2018 brasileiro logística 12137 12 137 12.13 793 79 3 79,3 IC95 IC (IC95 76,581,8 765818 76,5 81,8 76 5 81 8 76,5;81,8 106 10 6 10,6% ORa OR 1,29 129 29 1,101,50, 110150 1,10 1,50 , 50 1,10;1,50) 1,22 122 22 1,071,39, 107139 1,07 1,39 07 39 1,07;1,39) 1,19 119 19 1,051,34, 105134 1,05 1,34 05 34 1,05;1,34) R 100000 000 00 1.000,0 1,17 117 17 1,031,31, 103131 1,03 1,31 03 31 1,03;1,31) 1,28 128 28 1,151,42, 115142 1,15 1,42 15 42 1,15;1,42) 1,12 112 1,081,17, 108117 1,08 08 1,08;1,17) 10,69 1069 69 6,2718,20. 6271820 6,27 18,20 . 27 18 20 6,27;18,20) 2017201 201 2017-201 1213 13 12.1 7 79, IC9 (IC9 581 76,581, 76581 765 76, 818 81, 76,5;81, 10,6 1,2 101 1,101,50 11015 110 1,1 150 1,5 1,10;1,50 071 1,071,39 10713 107 1,0 139 1,3 0 1,07;1,39 11 051 1,051,34 10513 105 134 1,05;1,34 10000 1.000, 031 1,031,31 10313 103 131 1,03;1,31 151 1,151,42 11514 115 142 1,4 4 1,15;1,42 081 1,081,17 10811 108 1,08;1,17 2718 6,2718,20 627182 627 6,2 1820 18,2 6,27;18,20 201720 2017-20 121 12. (IC 58 76,581 7658 76,5;81 10, 1, 1,101,5 1101 1,10;1,5 1,071,3 1071 1,07;1,3 1,051,3 1051 1,05;1,3 1000 1.000 1,031,3 1031 1,03;1,3 1,151,4 1151 14 1,15;1,4 1,081,1 1081 1,08;1,1 271 6,2718,2 62718 62 6, 182 18, 6,27;18,2 20172 2017-2 76,58 76,5;8 1,101, 1,10;1, 1,071, 1,07;1, 1,051, 1,05;1, 100 1.00 1,031, 1,03;1, 1,151, 1,15;1, 1,081, 1,08;1, 6,2718, 6271 6,27;18, 2017- 76,5; 1,101 1,10;1 1,071 1,07;1 1,051 1,05;1 1.0 1,031 1,03;1 1,151 1,15;1 1,081 1,08;1 6,2718 6,27;18 1,10; 1,07; 1,05; 1. 1,03; 1,15; 1,08; 6,271 6,27;1 6,27;

ABSTRACT Objective To analyze measles, mumps, and rubella vaccination coverage among children up to 24 months old and factors associated with non-vaccination in a 2017−2018 live birth cohort, in state capitals and large interior region cities in Northeast Brazil. Methods Population-based survey analyzing vaccination coverage and sociodemographic factors through logistic regression. Results For 12,137 children, vaccination coverage was 79.3% (95%CI 76.5;81.8), and the dropout rate was 10.6%. Association with non-vaccination: socioeconomic stratum A (OR-a 1.29; 95%CI 1.10;1.50), living in the interior region (OR-a 1.22; 95%CI 1.07;1.39), no access to the Bolsa Família Program (OR-a 1.19, 95%CI 1.05;1.34), family income ≤BRL 1,000 (OR-a 1.17, 95%CI 1.03;1.31), mother not working (OR-a 1.28, 95%CI 1.15;1.42), >1 child per mother (OR-a 1.12, 95%CI 1.08;1.17), and no vaccination card (OR-a 10.69, 95%CI 6.27;18.20). Conclusion Low vaccination coverage and a high dropout rate in state capitals and municipalities in the interior region of Northeast Brazil. measles mumps 2 nonvaccination non 20172018 2017 2018 2017−201 cohort Brazil Populationbased Population based regression 12137 12 137 12,13 793 79 3 79.3 95CI CI 95 76.581.8, 765818 76.5 81.8 , 76 5 81 8 76.5;81.8) 106 10 6 10.6% ORa OR 1.29 129 1 29 1.101.50, 110150 1.10 1.50 50 1.10;1.50) 1.22 122 22 1.071.39, 107139 1.07 1.39 07 39 1.07;1.39) 119 19 1.19 1.051.34, 105134 1.05 1.34 05 34 1.05;1.34) BRL 1000 000 1,00 117 17 1.17 1.031.31, 103131 1.03 1.31 03 31 1.03;1.31) 128 28 1.28 1.151.42, 115142 1.15 1.42 15 42 1.15;1.42) > 112 1.12 1.081.17, 108117 1.08 08 1.08;1.17) 1069 69 10.69 6.2718.20. 6271820 6.27 18.20 . 27 18 20 6.27;18.20) 2017201 201 2017−20 1213 13 12,1 7 79. 9 581 76.581.8 76581 765 76. 818 81. 76.5;81.8 10.6 1.2 101 1.101.50 11015 110 1.1 150 1.5 1.10;1.50 071 1.071.39 10713 107 1.0 139 1.3 0 1.07;1.39 11 051 1.051.34 10513 105 134 1.05;1.34 100 00 1,0 031 1.031.31 10313 103 131 1.03;1.31 151 1.151.42 11514 115 142 1.4 4 1.15;1.42 081 1.081.17 10811 108 1.08;1.17 2718 6.2718.20 627182 627 6.2 1820 18.2 6.27;18.20 201720 2017−2 121 12, 58 76.581. 7658 76.5;81. 10. 1. 1.101.5 1101 1.10;1.5 1.071.3 1071 1.07;1.3 1.051.3 1051 1.05;1.3 1, 1.031.3 1031 1.03;1.3 1.151.4 1151 14 1.15;1.4 1.081.1 1081 1.08;1.1 271 6.2718.2 62718 62 6. 182 18. 6.27;18.2 20172 2017− 76.581 76.5;81 1.101. 1.10;1. 1.071. 1.07;1. 1.051. 1.05;1. 1.031. 1.03;1. 1.151. 1.15;1. 1.081. 1.08;1. 6.2718. 6271 6.27;18. 76.58 76.5;8 1.101 1.10;1 1.071 1.07;1 1.051 1.05;1 1.031 1.03;1 1.151 1.15;1 1.081 1.08;1 6.2718 6.27;18 76.5; 1.10; 1.07; 1.05; 1.03; 1.15; 1.08; 6.271 6.27;1 6.27;

resumen está disponible en el texto completo

https://doi.org/10.1590/s2237-96222024v33e20231296.especial2.en

Vaccination coverage, hesitancy and associated factors: a household survey of a cohort of children born in 2017 and 2018 in urban areas of state capital cities in the Brazilian Northeast coverage factors 201 20 2
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Saavedra, Ramon da Costa

; Santiago, Martha Suely Itaparica de Carvalho

; Teixeira, Maria da Glória Lima Cruz

; Antunes, Maria Bernadete de Cerqueira

; Queiroz, Rejane Christine de Sousa

; Lima, Luisa Helena de Oliveira

; Ramos Jr, Alberto Novaes

; Ferreira, Anderson Fuentes

; Maciel, Adjoane Mauricio Silva

; Barbosa, Jaqueline Caracas

; França, Ana Paula

; Domingues, Carla Magda Allan Santos

; Moraes, José Cássio de

; Silva, Adriana Ilha da

; Ramos Jr., Alberto Novaes

; França, Ana Paula

; Oliveira, Andrea de Nazaré Marvão

; Boing, Antonio Fernando

; Domingues, Carla Magda Allan Santos

; Oliveira, Consuelo Silva de

; Maciel, Ethel Leonor Noia

; Guibu, Ione Aquemi

; Mirabal, Isabelle Ribeiro Barbosa

; Barbosa, Jaqueline Caracas

; Lima, Jaqueline Costa

; Moraes, José Cássio de

; Luhm, Karin Regina

; Caetano, Karlla Antonieta Amorim

; Lima, Luisa Helena de Oliveira

; Antunes, Maria Bernadete de Cerqueira

; Teixeira, Maria da Glória Lima Cruz

; Teixeira, Maria Denise de Castro

; Borges, Maria Fernanda de Sousa Oliveira

; Queiroz, Rejane Christine de Sousa

; Gurgel, Ricardo Queiroz

; Barata, Rita Barradas

; Azevedo, Roberta Nogueira Calandrini de

; Oliveira, Sandra Maria do Valle Leone de

; Teles, Sheila Araújo

; Gama, Silvana Granado Nogueira da

; Mengue, Sotero Serrate

; Simões, Taynãna César

; Nascimento, Valdir

; Araújo, Wildo Navegantes de

Epidemiologia e Serviços de Saúde

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2024, Volume 33 N. spe2 elocation e20231298

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo Estimar a cobertura vacinal e analisar fatores sociodemográficos associados à não vacinação em crianças nascidas vivas em 2017 e 2018 nas capitais do Nordeste brasileiro. Métodos Realizou-se inquérito domiciliar com amostragem por conglomerados, entre 2020 e 2022, para estimar cobertura e hesitação vacinal. Fatores associados à não vacinação foram analisados usando-se regressão logística para calcular odds ratio (OR) e seus intervalos de confiança (IC95%). Resultados A capital com menores coberturas vacinais foi Natal, com < 75,0% para a maioria dos imunizantes; Teresina apresentou coberturas ≥ 90,0% em todos os imunizantes. Dos entrevistados, 99,1% (IC95% 98,9;99,3) acreditavam que vacinas são importantes para a saúde; 95,4% (IC95% 95,0;95,8) confiavam nos imunobiológicos distribuídos pelo governo; e 79,6% (IC95% 78,8;80,3) não tinham medo de reações adversas. Residir em estrato socioeconômico mais alto (OR ajustado: 1,34 – IC95% 1,20;1,50) foi fator associado à não vacinação. Conclusão As baixas coberturas destacam a necessidade de entender melhor as especificidades regionais e as desigualdades sociais. 201 brasileiro Realizouse Realizou se conglomerados 202 2022 usandose usando OR IC95%. IC95 IC . (IC95%) Natal 750 75 0 75,0 imunizantes 900 90 90,0 entrevistados 991 99 1 99,1 (IC95 98,999,3 989993 98,9 99,3 98 9 3 98,9;99,3 saúde 954 95 4 95,4 95,095,8 950958 95,0 95,8 8 95,0;95,8 governo 796 79 6 79,6 78,880,3 788803 78,8 80,3 78 80 78,8;80,3 adversas ajustado 134 34 1,3 1,201,50 120150 1,20 1,50 20 50 1,20;1,50 sociais IC9 7 75, 90, 99, (IC9 999 98,999, 98999 989 98, 993 98,9;99, 95, 095 95,095, 95095 950 958 95,0;95, 79, 880 78,880, 78880 788 78, 803 80, 78,8;80, 13 1, 1,201,5 12015 120 1,2 150 1,5 2 5 1,20;1,5 (IC 98,999 9899 98,9;99 09 95,095 9509 95,0;95 88 78,880 7888 78,8;80 1,201, 1201 12 15 1,20;1, 98,99 98,9;9 95,09 95,0;9 78,88 78,8;8 1,201 1,20;1 98,9; 95,0; 78,8; 1,20;

ABSTRACT Objective To estimate vaccination coverage and analyze sociodemographic factors associated with non-vaccination in children born in 2017 and 2018 in the state capitals of Northeast Brazil. Methods A household survey using cluster sampling was conducted from 2020-2022 to estimate vaccination coverage and hesitancy. Factors associated with non-vaccination were analyzed using logistic regression to calculate Odds Ratios (OR) and their Confidence Intervals (95%CI). Results Natal was the capital with the lowest vaccination coverage, below 75.0% for most immunizers. Teresina had rates equal to or greater than 90.0% for all vaccines. Among those interviewed, 99.1% (95%CI 98.9;99.3) believe that vaccines are important for health; 95.4% (95%CI 95.0;95.8) trust immunobiologicals and 79.6% (95%CI% 78.8;80.3) are not afraid of reactions. Belonging to the highest socioeconomic stratum (adjusted OR: 1.34 – 95%CI 1.20;1.50) was as a factor associated with non-vaccination. Conclusion Low coverage highlights the need for a better understanding of regional specificities and social inequalities. nonvaccination non 201 Brazil 20202022 2020 2022 2020-202 hesitancy OR (OR 95%CI. 95CI CI . 95 (95%CI) 750 75 0 75.0 immunizers 900 90 90.0 interviewed 991 99 1 99.1 98.999.3 989993 98.9 99.3 98 9 3 98.9;99.3 health 954 4 95.4 95.095.8 950958 95.0 95.8 8 95.0;95.8 796 79 6 79.6 95%CI% 78.880.3 788803 78.8 80.3 78 80 78.8;80.3 reactions adjusted 134 34 1.3 1.201.50 120150 1.20 1.50 20 50 1.20;1.50 nonvaccination. vaccination. inequalities 2020202 202 2020-20 7 75. 90. 99. 999 98.999. 98999 989 98. 993 98.9;99. 95. 095 95.095. 95095 950 958 95.0;95. 79. 880 78.880. 78880 788 78. 803 80. 78.8;80. 13 1. 1.201.5 12015 120 1.2 150 1.5 2 5 1.20;1.5 202020 2020-2 98.999 9899 98.9;99 09 95.095 9509 95.0;95 88 78.880 7888 78.8;80 1.201. 1201 12 15 1.20;1. 20202 2020- 98.99 98.9;9 95.09 95.0;9 78.88 78.8;8 1.201 1.20;1 98.9; 95.0; 78.8; 1.20;

resumen está disponible en el texto completo

https://doi.org/10.1590/s2237-96222024v33e20231298.especial2.en

Vaccination coverage and factors associated with incomplete polio vaccine schedule in children born in 2017-2018, in state capitals and interior region municipalities of Northeast Brazil 20172018, 20172018 2017 2018, 2018 2017-2018 2017201 201 2017-201 201720 20 2017-20 20172 2 2017-2 2017-
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Ramos Jr., Alberto Novaes

; Saavedra, Ramon da Costa

; Maciel, Adjoane Mauricio Silva

; Ferreira, Anderson Fuentes

; Silva, Taynara Lais

; Lima, Luisa Helena de Oliveira

; Domingues, Carla Magda Allan Santos

; Barbosa, Jaqueline Caracas

; Kerr, Ligia Regina Franco Sansigolo

; França, Ana Paula

; Silva, Pallysson Paulo da

; Teixeira, Maria da Gloria

; Moraes, José Cássio de

; Silva, Adriana Ilha da

; Ramos Jr., Alberto Novaes

; França, Ana Paula

; Oliveira, Andrea de Nazaré Marvão

; Boing, Antonio Fernando

; Domingues, Carla Magda Allan Santos

; Oliveira, Consuelo Silva de

; Maciel, Ethel Leonor Noia

; Guibu, Ione Aquemi

; Mirabal, Isabelle Ribeiro Barbosa

; Barbosa, Jaqueline Caracas

; Lima, Jaqueline Costa

; Moraes, José Cássio de

; Luhm, Karin Regina

; Caetano, Karlla Antonieta Amorim

; Lima, Luisa Helena de Oliveira

; Antunes, Maria Bernadete de Cerqueira

; Teixeira, Maria da Gloria

; Teixeira, Maria Denise de Castro

; Borges, Maria Fernanda de Sousa Oliveira

; Queiroz, Rejane Christine de Sousa

; Gurgel, Ricardo Queiroz

; Barata, Rita Barradas

; Azevedo, Roberta Nogueira Calandrini de

; Oliveira, Sandra Maria do Valle Leone de

; Teles, Sheila Araújo

; Gama, Silvana Granado Nogueira da

; Mengue, Sotero Serrate

; Simões, Taynãna César

; Nascimento, Valdir

; Araújo, Wildo Navegantes de

Epidemiologia e Serviços de Saúde

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- SciELO Analytics

2024, Volume 33 N. spe2 elocation e20231219

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo Analisar a cobertura vacinal e os fatores associados ao esquema incompleto das vacinas contra a poliomielite em coorte de nascidos vivos de 2017-2018, em capitais e municípios do interior do Nordeste brasileiro. Métodos Inquérito domiciliar em crianças com idade ≤ 24 meses, entre 2020 e 2022. Estimaram-se a cobertura vacinal, a taxa de abandono e fatores associados ao esquema de vacinação incompleto, analisados pela razão de chances (odds ratio, OR) e intervalos de confiança de 95% (IC95%). Resultados Em 12.137 crianças, a cobertura vacinal (quatro doses) foi de 80,9% (IC95% 78,4;83,1); 8,4% não eram vacinadas. Não possuir caderneta de vacinação (OR = 14,05; IC95% 8,54;23,12) e uso de serviço privado (OR = 1,46; IC95% 1,23;1,74) estiveram associados à vacinação incompleta. Taxas de abandono mais altas foram observadas na dose de reforço, principalmente no estrato alto. Conclusão Observaram-se baixas coberturas, redução no seguimento das doses e elevadas taxas de abandono para vacinas contra a poliomielite nas áreas estudadas. 20172018, 20172018 2017 2018, 2018 2017-2018 brasileiro 2 meses 202 2022 Estimaramse Estimaram se odds ratio OR 95 IC95%. IC95 IC . (IC95%) 12137 12 137 12.13 quatro 809 80 9 80,9 (IC95 78,483,1 784831 78,4 83,1 78 4 83 1 78,4;83,1) 84 8 8,4 vacinadas 14,05 1405 14 05 8,5423,12 8542312 8,54 23,12 54 23 8,54;23,12 1,46 146 46 1,231,74 123174 1,23 1,74 74 1,23;1,74 incompleta reforço alto Observaramse Observaram coberturas estudadas 2017201 201 2017-201 20 IC9 1213 13 12.1 80, (IC9 483 78,483, 78483 784 78, 831 83, 7 78,4;83,1 8, 14,0 140 0 5423 8,5423,1 854231 854 8,5 2312 23,1 5 8,54;23,1 1,4 231 1,231,7 12317 123 1,2 174 1,7 1,23;1,7 201720 2017-20 121 12. (IC 48 78,483 7848 78,4;83, 14, 542 8,5423, 85423 85 23, 8,54;23, 1, 1,231, 1231 17 1,23;1, 20172 2017-2 78,48 78,4;83 8,5423 8542 8,54;23 1,231 1,23;1 2017- 78,4;8 8,542 8,54;2 1,23; 78,4; 8,54;

ABSTRACT Objective To analyse vaccination coverage and factors associated with incomplete polio vaccination in a cohort of children born in 2017-2018, in state capitals and interior region municipalities of Northeast Brazil. Methods Household survey of children aged ≤24 months conducted between 2020 and 2022. Vaccination coverage and dropout rates were estimated, as well as factors associated with incomplete vaccination, analyzed by calculating odds ratios (OR) and 95% confidence intervals (95%CI). Results : Among 12,137 children, vaccination coverage (4 doses) was 80.9% (95%CI 78.4;83.1); 8.4% were not vaccinated. Not having a vaccination card (OR=18.06; 95%CI 10.01;32.61) and use of private services (OR=1.46; 95%CI 1.23;1.74) were associated with incomplete vaccination. Higher dropout rates were found for the booster dose, especially in the highest stratum. Conclusion Low vaccination coverage, poor dose follow-up and high dropout rates were found for polio vaccines in the areas studied. 20172018, 20172018 2017 2018, 2018 2017-2018 Brazil 24 ≤2 202 2022 estimated OR (OR 95 95%CI. 95CI CI . (95%CI) 12137 12 137 12,13 4 ( doses 809 80 9 80.9 78.483.1 784831 78.4 83.1 78 83 1 78.4;83.1) 84 8 8.4 vaccinated OR=18.06 OR1806 18 06 (OR=18.06 10.0132.61 10013261 10.01 32.61 10 01 32 61 10.01;32.61 OR=1.46 OR146 46 (OR=1.46 1.231.74 123174 1.23 1.74 23 74 1.23;1.74 stratum followup follow up studied 2017201 201 2017-201 2 ≤ 20 1213 13 12,1 80. 483 78.483. 78483 784 78. 831 83. 7 78.4;83.1 8. OR=18.0 OR180 0 (OR=18.0 0132 10.0132.6 1001326 1001 10.0 3261 32.6 3 6 10.01;32.6 OR=1.4 OR14 (OR=1.4 231 1.231.7 12317 123 1.2 174 1.7 1.23;1.7 201720 2017-20 121 12, 48 78.483 7848 78.4;83. OR=18. OR18 (OR=18. 013 10.0132. 100132 100 10. 326 32. 10.01;32. OR=1. OR1 (OR=1. 1.231. 1231 1. 17 1.23;1. 20172 2017-2 78.48 78.4;83 OR=18 (OR=18 10.0132 10013 10.01;32 OR=1 (OR=1 1.231 1.23;1 2017- 78.4;8 10.013 10.01;3 OR= (OR= 1.23; 78.4; 10.01;

resumen está disponible en el texto completo

https://doi.org/10.1590/s2237-96222024v33e20231219.especial2.en

Measles, mumps and rubella vaccination coverage in capitals and interior region municipalities of Northeast Brazil: a household survey in a cohort of children born in 2017 and 2018
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Maciel, Adjoane Mauricio Silva

; Ramos Jr, Alberto Novaes

; Ferreira, Anderson Fuentes

; Silva, Taynara Lais

; Domingues, Carla Magda Allan Santos

; Saavedra, Ramon da Costa

; Barbosa, Jaqueline Caracas

; França, Ana Paula

; Kerr, Ligia Regina Franco Sansigolo

; Teixeira, Maria da Gloria

; Moraes, José Cássio de

; Silva, Adriana Ilha da

; Ramos Jr., Alberto Novaes

; França, Ana Paula

; Oliveira, Andrea de Nazaré Marvão

; Boing, Antonio Fernando

; Domingues, Carla Magda Allan Santos

; Oliveira, Consuelo Silva de

; Maciel, Ethel Leonor Noia

; Guibu, Ione Aquemi

; Mirabal, Isabelle Ribeiro Barbosa

; Barbosa, Jaqueline Caracas

; Lima, Jaqueline Costa

; Moraes, José Cássio de

; Luhm, Karin Regina

; Caetano, Karlla Antonieta Amorim

; Lima, Luisa Helena de Oliveira

; Antunes, Maria Bernadete de Cerqueira

; Teixeira, Maria da Gloria

; Teixeira, Maria Denise de Castro

; Borges, Maria Fernanda de Sousa Oliveira

; Queiroz, Rejane Christine de Sousa

; Gurgel, Ricardo Queiroz

; Barata, Rita Barradas

; Azevedo, Roberta Nogueira Calandrini de

; Oliveira, Sandra Maria do Valle Leone de

; Teles, Sheila Araújo

; Gama, Silvana Granado Nogueira da

; Mengue, Sotero Serrate

; Simões, Taynãna César

; Nascimento, Valdir

; Araújo, Wildo Navegantes de

Epidemiologia e Serviços de Saúde

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2024, Volume 33 N. spe2 elocation e20231296

Abstract: En Pt Es | Text: En Pt Es | PDF: En | PDF: Pt | PDF: Es

resumen está disponible en el texto completo

https://doi.org/10.1590/s2237-96222024v33e20231296.especial2.en

Susceptibilidad genética y aclaramiento viral de la infección por virus de la hepatitis C
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Saavedra-Chacón, María Fernanda

; Navas, María Cristina

; Suárez-Díaz, Neys

; Uribe-Delgado, José Roberto

Iatreia

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dec 2023, Volume 36 N. 4 Pages 550 - 561

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Hepatitis C virus (HCV) remains a major cause of chronic hepatitis in the Western world. Spontaneous viral clearance occurs in 15% to 40% of individuals with acute HCV infection; however, the factors and variables associated with this phenomenon are not fully elucidated. Understanding the mechanisms of HCV infection pathogenesis is crucial for identifying factors and variables involved in spontaneous clearance or persistence of infection. Host factors associated with spontaneous viral clearance during acute infection, such as polymorphisms in the interleukin-28 gene (IL28B) encoding interferon lambda 3 (IFNL3), have been documented in some studies. The objective of this article is to provide a literature review on the physiopathology of HCV infection and describe the evidence concerning the role of IL28B gene polymorphisms and their impact on the process of spontaneous viral clearance, as well as other aspects of the natural history and treatment of the infection.

Resumen El virus de la hepatitis C (VHC) sigue siendo una de las principales causas de hepatitis crónica en el mundo occidental. Del 15% al 40% de los individuos con infección aguda por VHC logran el aclaramiento viral espontáneo; sin embargo, los factores y variables asociadas a este fenómeno no están completamente descritas. El análisis de los mecanismos de patogénesis de la infección por VHC es indispensable para identificar los factores y variables implicadas en el aclaramiento espontáneo o en la persistencia de la infección. En algunos estudios se han documentado los factores del huésped asociados al aclaramiento viral espontáneo durante la infección aguda, entre ellos el polimorfismo del gen de la interleucina -28 (IL28B) que codifica para el interferón lambda 3 (IFNL3). El objetivo de este artículo es realizar una revisión de la literatura sobre la fisiopatología de la infección por el VHC y describir la evidencia acerca del papel de los polimorfismos en el gen IL28B y su impacto en el proceso de aclaramiento viral espontáneo, así como en otros aspectos de la historia natural y el tratamiento de la infección.

https://doi.org/10.17533/udea.iatreia.213

Taller de concordancia en la evaluación de imágenes capilaroscópicas
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Izaguirre, Pía

; Romanini, Félix Enrique

; Mamani, Marta

; Montoya, Sandra Fabiana

; Toibar, Javier

; Catalán Pellet, Santiago

; Sirera, Ana Irene

; Dueñas, Lelly

; Cucchiaro, Natalia

; Cousseau, Mario

; Orellana González, Carlos Alberto

; Yucra, Demelza

; Tralice, Elda Rossella

; Raschia, Alan Juan

; Molina, María Josefina

; Lencia, María Verónica

; Espasa, Gabriela Vanesa

; Linarez Martínez, Miguel Alex

; Castro Coello, Vanesa Viviana

; García, Aldo

; Velloso, María Sofía

; González, Paula Alejandra

; German, Noelia Fernanda

; Conti, Silvana

; Savy, Florencia

; Morbiducci, Julieta Silvana

; Rivero, Mariano

; Saavedra, Leandro José

; Sabelli, Mirtha Rosa

; Rebak, Jonathan Eliseo

; Rojas Tessel, Romina

; Sorrentino, Laura

; Gervasoni, Viviana Lorena

; Marcantoni, María Beatriz

; Gervilla de Cafrune, Ana Lía

; Got, Julio

; Sánchez, Gabriela

; Castorino, Gerardo

; García, Lucila

; Sansinanea, Pierina

; Tamborenea, María Natalia

Revista argentina de reumatología

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oct 2022, Volume 33 N. 4 Pages 223 - 227

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Introducción: la capilaroscopia es un método no invasivo que permite observar la microvasculatura en el área periungueal. Los resultados informados pueden ser altamente variables entre distintos observadores. A lo largo del tiempo surgieron métodos cuantitativos y semicuantitativos para mejorar la reproducibilidad. Objetivos: conocer el nivel de acuerdo intra e interobservador al informar los diferentes patrones capilaroscópicos en individuos con diferente nivel de entrenamiento. Materiales y métodos: estudio de corte transversal. Participaron médicos reumatólogos especialistas y en formación que habían realizado previamente un curso virtual de capacitación en capilaroscopia. Recibieron 40 imágenes capilaroscópicas proyectadas en una presentación de PowerPoint y debían responder a través de un cuestionario digital. Se evaluó la concordancia de respuestas intra e interobservador. Resultados: se encontró un alto nivel de concordancia global con un kappa 0,66 IC 95% (0,63-0,70) p<0,0000. También en otros grupos como reumatólogos en formación: kappa 0,65 IC 95% (0,60-0,71) p=0,0000, y médicos reumatólogos: kappa 0,67 IC 95% (0,62-0,72) p=0,0000. Conclusiones: el nivel de concordancia encontrado fue globalmente alto, independientemente del nivel de entrenamiento de los profesionales, y de ser o no reumatólogo. La concordancia fue superior cuando se comparó a quienes tenían más de 4 años de experiencia en la realización de videocapilaroscopia.

Abstract Introduction: videoapillaroscopy is a non-invasive method that allows the observation of the microvasculature in the periungual area. Reported results can be highly variable between different observers. Over time, quantitative and semi-quantitative methods emerged to improve reproducibility. Objetives: to know the level of intra and interobserver agreement when reporting the different capillaroscopic patterns in individuals with different levels of training. Materials and methods: cross section study. Specialist rheumatologists and those in training who had previously completed a virtual capillaroscopy training course participated. They received 40 capillaroscopic images projected in a PowerPoint presentation and had to issue their response through a digital questionnaire. Concordance of intra and interobserver responses was evaluated. Results: a high level of global agreement was found with a kappa 0.66 CI 95% (0.63-0.70) p<0.0000, also in other groups such as rheumatologists in training: kappa 0.65 CI 95% (0.60-0.71) p=0.0000, physicians rheumatologists: kappa 0.67 95% CI (0.62-0.72) p=0.0000. Conclusions: the level of agreement found was globally high, regardless of the level of training of the professionals, and whether or not they were a rheumatologist. Concordance was higher when compared to those who had more than 4 years of experience performing videocapillaroscopy.

https://doi.org/10.47196/rar.v33i4.709

Abordaje periodístico sobre la adopción de niños en Colombia entre los años 2008 al 2020
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Estrada Jaramillo, Lina Marcela

; Montes Rodríguez, Luisa María

; Díaz Bertel, Judith Cecilia

; Vergara Guzmán, Daniela

; Saavedra Jaimes, Alisson Estefania

; Jaramillo González, Andrea

; Mena Calderón, Luisa Fernanda

; Zuleta Hurtado, Naudin

; Gómez Sánchez, Karen Johanna

; Arboleda Ospina, Melisa

; Suarez Polanco, Silvia Patricia

Revista CES Derecho

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jun 2022, Volume 13 N. 1 Pages 4 - 26

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract The research analyzed the journalistic approach to the adoption of children in Colombia between 2008 and 2020, based on a documentary scan and content analysis carried out from the review of the written media with the greatest coverage and experience in the country. (El Espectador, El Tiempo, El Colombiano and Semana Magazine). 554 newspaper articles were obtained between the years 2014 to 2020, having as the subject of greatest coverage the debates on the proposed referendum to exclude same-sex couples and single people as alleged adoptive parents. It is concluded that the media do not contrast the informative content with social actors directly linked to the process such as children and adoptive families, nor with the governing body of the adoption program - ICBF-, evidencing that the The main source is politics based on the issue being discussed.

Resumen La investigación analizó el abordaje periodístico de la adopción de niños en Colombia entre los años 2008 al 2020, a partir de un rastreo documental y análisis de contenido realizado a partir de la revisión de los medios de comunicación escritos con mayor cobertura y trayectoria en el país (El Espectador, El Tiempo, El Colombiano y Revista Semana). Se obtuvieron 554 artículos periodísticos entre los años 2014 a 2020, teniendo como tema de mayor cobertura los debates del referendo propuesto para excluir a las parejas del mismo sexo y a las personas solteras como pretensos padres adoptantes. Se concluyó que los medios de comunicación no contrastan el contenido informativo con actores sociales directamente vinculados al proceso como los niños, las familias adoptantes y el organismo rector del programa de adopción - ICBF-, poniendo en evidencia que la fuente principal es política a partir de la temática que se discute.

https://doi.org/10.21615/cesder.6400 124 downloads

Respuesta inmune y vírica en el espacio exterior
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Saavedra-Torres, Jhan Sebastián

; Muñoz Gallego, Flor de María

; Pinzón Fernández, María Virginia

; Zúñiga-Cerón, Luisa Fernanda

Revista Cubana de Medicina

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dec 2021, Volume 60 N. 4 elocation e2471

Abstract: Es | Text: Es | PDF: Es

10.

Consideraciones acerca del “Estudio de los gemelos de la NASA: un vuelo espacial humano de un año”
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Sebastián Saavedra-Torres, Jhan

; Zúñiga Cerón, Luisa Fernanda

; Muñoz Gallego, Flor de María

; Pinzón Fernández, María Virginia

Revista Cubana de Medicina

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dec 2021, Volume 60 N. 4 elocation e2167

Abstract: Es | Text: Es | PDF: Es

11.

Complicaciones neurológicas por COVID-19
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Sebastián Saavedra-Torres, Jhan

; Pinzón Fernández, María Virginia

; Zúñiga Cerón, Luisa Fernanda

; Salguero Bermúdez, Carolina

; Zamora Bastidas, Tomas Omar

Revista Cubana de Medicina

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dec 2021, Volume 60 N. 4 elocation e1684

Abstract: Es | Text: Es | PDF: Es

12.

Métodos para avaliação da efetividade de vacinas para COVID-19 com ênfase em abordagens quase-experimentais
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Pescarini, Julia Moreira

; Teixeira, Camila Silveira Silva

; Cruz, Enny Paixão

; Ortelan, Naia

; Pinto, Priscila Fernanda Porto Scaff

; Ferreira, Andrêa Jacqueline Fortes

; Alves, Flavia Jôse Oliveira

; Pinto Junior, Elzo Pereira

; Falcão, Ila Rocha

; Rocha, Aline dos Santos

; Silva, Nivea Bispo da

; Ortiz, Renzo Flores

; Saavedra, Ramon da Costa

; Oliveira, Vinicius de Araújo

; Ribeiro-Silva, Rita de Cássia

; Ichihara, Maria Yury Travassos

; Boaventura, Viviane

; Barral Netto, Manoel

; Kerr, Ligia Regina Franco Sansigolo

; Werneck, Guilherme Loureiro

; Barreto, Mauricio L.

Ciência & Saúde Coletiva

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nov 2021, Volume 26 N. 11 Pages 5599 - 5614

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A avalição da efetividade de vacinas é feita com dados do mundo real e é essencial para monitorar o desempenho dos programas de vacinação ao longo do tempo bem como frente a novas variantes. Até o momento, a avaliação da efetividade das vacinas para COVID-19 tem sido baseada em métodos clássicos como estudos de coorte e caso controle teste-negativo, que muitas vezes podem não permitir o adequado controle dos vieses intrínsecos da alocação das campanhas de vacinação. O objetivo dessa revisão foi discutir os desenhos de estudo disponíveis para avaliação de efetividade das vacinas, enfatizando os estudos quase-experimentais, que buscam mimetizar os estudos aleatorizados ao introduzir um componente exógeno para atribuição ao tratamento, bem como suas vantagens, limitações e aplicabilidade no contexto dos dados brasileiros. O emprego de métodos quase-experimentais, incluindo as séries temporais interrompidas, o método de diferença em diferenças, escore de propensão, variáveis instrumentais e regressão descontínua, são relevantes pela possibilidade de gerar estimativas mais acuradas da efetividade de vacinas para COVID-19 em cenários como o brasileiro, que se caracteriza pelo uso de várias vacinas, com respectivos número e intervalos entre doses, aplicadas em diferentes faixas etárias e em diferentes momentos da pandemia.

Abstract The evaluation of vaccine effectiveness is conducted with real-world data. They are essential to monitor the performance of vaccination programmes over time, and in the context of the emergence of new variants. Until now, the effectiveness of COVID-19 vaccines has been assessed based on classic methods, such as cohort and test-negative case-control studies, which may often not allow for adequate control of inherent biases in the assignment of vaccination campaigns. The aim of this review was to discuss the study designs available to evaluate vaccine effectiveness, highlighting quasi-experimental studies, which seek to mimic randomized trials, by introducing an exogenous component to allocate to treatment, in addition to the advantages, limitations, and applicability in the context of Brazilian data. The use of quasi-experimental approaches, such as interrupted time series, difference-in-differences, propensity scores, instrumental variables, and regression discontinuity design, are relevant due to the possibility of providing more accurate estimates of COVID-19 vaccine effectiveness. This is especially important in scenarios such as the Brazilian, which characterized by the use of various vaccines, with the respective numbers and intervals between doses, applied to different age groups, and introduced at different times during the pandemic.

https://doi.org/10.1590/1413-812320212611.18622021 1 downloads

13.

Enfermedad del hígado graso asociada con la disfunción metabólica. Una nueva propuesta para una dolencia en auge
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Saavedra-Chacón, María Fernanda

; Pérez, Santiago

; Guevara, Luis Gonzalo

Iatreia

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sep 2021, Volume 34 N. 3 Pages 241 - 252

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN La enfermedad por hígado graso no alcohólica se caracteriza por la acumulación de grasa hepática que excede el 5 % de su peso. El espectro de esta condición incluye la esteatosis hepática, esteatohepatitis y fibrosis progresiva con cirrosis. Además, existe la posibilidad de desarrollar hepatocarcinoma sin el antecedente de cirrosis. Su fisiopatología se basa actualmente en el componente metabólico y se considera como la manifestación hepática de una disfunción metabólica sistémica. La acumulación de grasa causa citotoxicidad, inflamación y fibrosis. Debido al auge en su investigación, se ha propuesto el término de enfermedad del hígado graso asociado con una disfunción metabólica, confiriéndole unos criterios diagnósticos claros y retirando el concepto como entidad de descarte. El diagnóstico incluye la documentación de esteatosis hepática y fibrosis como marcador pronóstico mediante estudios imagenológicos y puntajes bioquímicos. El tratamiento consiste en la reducción del peso y mejorar la condición metabólica basal. Actualmente, se encuentran en estudio nuevos fármacos que buscan interferir con la inflamación hepática. El manejo incluye, además, el control del riesgo cardiovascular y de otras enfermedades concomitantes.

SUMMARY Nonalcoholic fatty liver disease is characterized by fat accumulation in the liver exceeding 5% of its weight. The spectrum of the disease includes fatty liver, steatohepatitis and progressive fibrosis leading to cirrhosis. It is also possible to develop hepatocellular carcinoma even without cirrhosis. Its physiopathology highlights the metabolic component of the disease, being acknowledged as a hepatic expression of a multisystemic metabolic disorder. Fat accumulation causes apoptosis, inflammation and fibrosis. In the view of the rising research on the subject, a new terminology is being proposed, consisting in metabolic associated fatty liver disease, now perceived as a standalone condition not needing the exclusion of other entities to make a diagnosis. The diagnosis includes the identification of liver steatosis and fibrosis, as a prognosis marker, using imaging studies and scoring models with biochemical markers. Treatment consists primarily in weight reduction and improving the metabolic baseline condition. New studies seeking pharmacologic interventions targeting hepatic inflammation are being conducted. Therapy also includes appropriate management of other medical comorbidities and cardiovascular risk control.

https://doi.org/10.17533/udea.iatreia.101 659 downloads

14.

Síndrome antifosfolípido (SAF): diferencias clínicas e inmunoserológicas entre SAF primario y secundario en una cohorte colombiana
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Díaz-Coronado, Juan Camilo

; Herrera-Uribe, Sebastián

; Hernández-Parra, Deicy

; Betancur-Vásquez, Laura

; Lacouture-Fierro, Jorge

; González-Hurtado, Daniel

; González-Arango, Juanita

; Uribe-Arango, Laura

; Saavedra-Chacón, María Fernanda

; Monsalve-Yepes, Santiago

; Guerra-Zarama, Sebastián

; Serna-Giraldo, José David

; López-López, Juan David

; Barbosa-Arana, Julián

; Soto-Osorio, María Camila

; Durango, Yecenia

; Pineda-Tamayo, Ricardo A.

Revista Colombiana de Reumatología

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sep 2021, Volume 28 N. 3 Pages 191 - 196

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN Introducción: El síndrome antifosfolípido (SAF) es una enfermedad autoinmune sistémica, caracterizada por trombosis recurrente, que puede afectar la circulación arterial y venosa. Objetivo: Analizar las diferencias inmunológicas y farmacológicas, así como los desenlaces clínicos de una cohorte de pacientes con SAF primario y secundario. Materiales y métodos: Estudio de corte transversal que incluyó 352 pacientes con diagnóstico de SAF atendidos entre los arios 2014 y 2018. Se analizaron variables sociodemográficas, clínicas e inmunológicas y se realizó un análisis univariado y un análisis bivariado mediante la prueba chi-cuadrado para determinar diferencias entre los pacientes con SAF primario y SAF secundario. Finalmente, se hizo un análisis multivariado para buscar asociaciones con los desenlaces clínicos trombóticos en los pacientes con SAF. Resultados: La edad promedio de la población fue de 42,4 ± 14 años; el 84,6% correspondió a sexo femenino. El 67,6% de los pacientes tenía diagnóstico de SAF primario y un 32,4% de SAF secundario, siendo el lupus eritematoso sistémico (LES) la enfermedad asociada en un 84%. Dentro de los eventos trombóticos, el más frecuente fue la trombosis venosa profunda (17,3%), seguida por el ataque cerebrovascular (9,9%). En los eventos obstétricos existió una prevalencia del 39,4% para abortos. No se encontraron diferencias en el perfil sociodemográfico ni en el perfil inmunoserológico entre los pacientes con diagnóstico de SAF primario y aquellos con SAF secundario. Los eventos trombóticos tuvieron mayor frecuencia en el grupo de SAF primario, pero solo la tromboembolia pulmonar alcanzó significación estadística. Eventos obstétricos como los abortos no fueron diferentes entre ambos grupos. Dentro de los factores asociados a los eventos trombóticos, se encontró que el sexo femenino tiene una probabilidad 5 veces mayor de accidente cerebrovascular y 3 veces mayor de trombosis venosa profunda. Los anti- β2GPI tipo IgM aumentaron alrededor de 3 veces la probabilidad de presentar abortos en mujeres con SAF. Conclusión: Se presenta una de las cohortes colombianas más grandes de pacientes con SAF reportadas hasta el momento en la literatura. La población es comparable clínica y sociodemográficamente con lo encontrado en otros estudios, aunque la prevalencia de SAF primario fue mayor y las complicaciones trombóticas fueron menores. La tromboembolia pulmonar fue significativamente mayor en el grupo de SAF primario.

ABSTRACT Introduction: Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by recurrent thrombosis that can affect the arterial and venous circulation. Objective: To analyze the immunological and pharmacological differences, as well as the clinical outcomes of a cohort of patients with primary APS and secondary APS. Materials and methods: A retrospective cohort study was conducted that included 352 records of patients diagnosed with APS and treated between 2014 and 2018. A description is presented of the sociodemographic, clinical, and immunological profile of the population. A bivariate analysis performed using the chi-squared test to determine differences between groups with primary APS and secondary APS, and finally a multivariate analysis to search for associations with thrombotic clinical outcomes in patients with APS. Results: The mean age was 42.4 ± 14 years, and 84.6% were females. Two-thirds (67.6%) of the patients had a diagnosis of primary APS, and 32.4% of secondary APS, of which 84% were associated with systemic lupus erythematosus (SLE). Among the thrombotic events, the most frequent were deep vein thrombosis (17.3%) and stroke (9.9%). Obstetric events were frequent, with a prevalence of 39.4% for miscarriages. No differences were found in the sociodemographic or immunoserological profile when comparing the group of primary vs. secondary APS. Thrombotic events were more frequent in the primary APS group, although only pulmonary embolism reached statistical significance. There were no differences between the two groups as regards obstetric events, such as miscarriages. Women were found to be 5 times more likely to have a stroke and 3 times more to have deep vein thrombosis. The anti-β2GPI type IgM increased the probability of presenting miscarriages about 3 times in women with APS. Conclusion: The study contains one of the largest Colombian cohorts with APS reported so far, and although it is both clinically and sociodemographically similar to other cohorts, there is a higher prevalence of primary APS. There was a lower frequency of thrombotic complications compared to other cohorts. Patients with primary APS had a tendency to develop thrombosis, as has already been reported in the literature.

https://doi.org/10.1016/j.rcreu.2020.10.002 77 downloads

15.

Contaminación Bacteriana del Aerosol Dental con y sin Uso de una Cúpula de Acrílico en un Paciente en Pandemia COVID-19
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Venegas-Arques, María Cecilia

; Rojas-García, Carolina Pia

; Cataldo-Saavedra, Yuri Andrés

; Jiménez-Gomez, Paula Fernanda

; Arqués-Vergara, Victoria Inés

; Martinez, Benjamín

International journal of odontostomatology

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mar 2021, Volume 15 N. 1 Pages 14 - 22

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT: In the current PANDEMIC for COVID- 19, the clinical world has been forced to reinforce the use of protection in healthcare, due to the high degree of contagion and virulence of this virus. In dentistry, due to the production of aerosols, clinical care has been suspended to prevent infection. The objective of this research is to determine the amount of bacterial contamination, generated by the use of high-speed micromotor aerosol, carried out by dentists at the Hospital de La Florida, Santiago, Chile. The study included 10 patients per box, with 2 samples per patient, in total 40 culture plates, 20 Control, 20 Test and 3 Environmental. The culture medium was kept for 10 minutes, located in the front of the operator and the patient's chest. Simulation of the operation with a turbine was performed, without absolute isolation, with and without the use of an acrylic dome, placed on a healthy patient. The samples were analyzed macroscopically, incubated at 37ºC in an atmosphere of oxygen for 24 hours and Carbon dioxide after 48 hours. 43 plates were positive, noting a non-significant difference (p = 0.753) between the two groups in the bib samples, with an average difference of 56.76 CFU. In the plates of the operator's forehead, an average of 8.1 CFU in the box without dome and 3.9 CFU in the box with dome, finding a statistically significant difference (p = 0.0391). The environmental plates 28.33 UFC in the Box with the dome, 29 UFC in the Control Box and the Box without dome 46.66 UFC. When verifying that the acrylic dome effectively contains aerosols, it should be used as a biosafety standard to protect both dental equipment and patients in times of pandemic against COVID-19.

RESUMEN: En la actual pandemia por COVID-19, el mundo clínico se ha visto obligado a reforzar el uso de protección en el quehacer asistencial, debido al alto grado de contagio y virulencia de este virus. En odontología, debido a la producción de aerosoles, se han suspendido las atenciones clínicas para prevenir contagios. El objetivo de esta investigación es determinar la cantidad de contaminación bacteriana, generada por el uso de aerosol con micromotor de alta velocidad, realizado por dentistas del Hospital de La Florida, Santiago de Chile. El estudio contó con 10 pacientes por box, con 2 muestras por paciente, en total 40 placas de cultivo, 20 Control, 20 Prueba y 3 Ambientales. El medio de cultivo se mantuvo por 10 minutos, ubicado en la frente del ope rador y pechera del paciente, se realizó simulación de operatoria con turbina, sin aislamiento absoluto, con y sin uso de una cúpula de acrílico, puesta en un paciente sano. Las muestras fueron analizadas macroscópicamente, incubadas a 37 ºC en una atmósfera de oxígeno por 24 horas y dióxido de Carbono a las 48 horas. 43 placas fueron positivas, observándose, en las muestras de la peche ra una diferencia no significativa (p=0,753) entre ambos grupos, con una diferencia promedio de 56,76 UFC. En las placas de la fre nte del operador, un promedio de 8.1 UFC en Box sin cúpula y 3,9 UFC en el box con cúpula, encontrándose diferencia estadísticament e significativa (p= 0,0391). Las placas ambientales 28,33 UFC en el Box con cúpula, 29 UFC en el Box control y Box sin cúpula 46, 66 UFC. Al comprobar que la cúpula de acrílico contiene eficazmente los aerosoles, corresponde utilizarlo como norma de biosegurid ad para proteger tanto al equipo dental, como a los pacientes en tiempos de pandemia contra el COVID-19.

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ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

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