ABSTRACT Background Nutritional status and daily physical activity (PA) may be an excellent tool for the maintenance of bone health in patients with cystic fibrosis (CF). Objective To evaluate the relationship between nutritional status, daily physical activity and bone turnover in cystic fibrosis patients. Method A cross-sectional study of adolescent and adult patients diagnosed with clinically stable cystic fibrosis was conducted. Total body, femoral neck, and lumbar spine bone mineral density (BMD) were determined by dual energy X-ray absorptiometry and bone metabolism markers ALP, P1NP, PICP, and ß-CrossLaps. PA monitoring was assessed for 5 consecutive days using a portable device. Exercise capacity was also determined. Serum 25-hydroxyvitamin D and vitamin K were also determined in all participants. Results Fifty patients (median age: 24.4 years; range: 16-46) were included. BMI had positive correlation with all BMD parameters, with Spearman’s coefficients ranging from 0.31 to 0.47. Total hip bone mineral density and femoral neck BMD had positive correlation with the daily time spent on moderate PA (>4.8 metabolic equivalent-minutes/day; r=0.74, p<0.001 and r=0.72 p<0.001 respectively), daily time spent on vigorous PA (>7.2 metabolic equivalent-minutes/day; r=0.45 p<0.001), body mass index (r=0.44, p=0.001), and muscle mass in limbs (r=0.41, p=0.004). Levels of carboxy-terminal propeptide of type 1 collagen were positively associated with the daily time spent on moderate (r=0.33 p=0.023) and vigorous PA (r=0.53, p<0.001). Conclusions BMI and the daily time spent on moderate PA were found to be correlated with femoral neck BMD in CF patients. The association between daily PA and biochemical markers of bone formation suggests that the level of daily PA may be linked to bone health in this patient group. Further research is needed to confirm these findings.

INTRODUÇÃO: O exercício físico é considerado um dos componentes para melhoria das condições de saúde em diabéticos tipo 2. Além disso, alguns estudos têm sugerido que níveis mais elevados de aptidão física também podem melhorar a qualidade de vida relacionada à saúde (QVRS). No entanto, não existem estudos publicados que sejam especificamente concebidos para examinar esta relação. OBJETIVO: O objetivo do presente estudo foi avaliar o efeito do nível de atividade física sobre a aptidão física e QVRS e determinar se existem diferenças quando indivíduos com e sem diabetes mellitus tipo 2 são comparados. MÉTODO: Cinquenta e quatro participantes com diabetes tipo 2 e 54 participantes pareados por idade sem diabetes foram voluntários para participar deste estudo. A aptidão física (teste de levantar da cadeira de 30 segundos, teste de caminhada de seis minutos e teste de sentar e alcançar) e QVRS (VC-36) foram avaliadas. RESULTADOS: Os participantes com diabetes tipo 2 apresentaram menores escores médios para o teste de sentar e alcançar e uma maior pontuação em relação ao escore do componente mental do que os controles. Quando os dois grupos foram classificados quanto ao nível de atividade física, foram encontradas diferenças significativas em relação a função social, saúde mental, saúde geral e vitalidade, entre os pacientes insuficiente e minimamente ativos. CONCLUSÃO: Os participantes com maiores níveis de prática de atividade física também relataram melhor aptidão física, a qual, juntamente com as melhorias na QVRS, pode ter implicações clínicas na prevenção e tratamento do diabetes mellitus tipo 2.

INTRODUCTION: Physical exercise is considered to improve different health outcomes in type 2 diabetic patients. In addition, a few studies have suggested that higher levels of fitness might also enhance health-related quality of life (HRQoL). However, there are no published studies that were specifically designed to examine this relationship. OBJECTIVE: The aim of the current study was to assess the effect of physical activity level on physical fitness and HRQoL and determine whether differences existed when comparing people with and without type 2 diabetes mellitus. METHODS: Fifty-four participants with type 2 diabetes and 54 age-matched participants without diabetes volunteered to participate in this study. Physical fitness (30-second chair stand test, six-min walk test and sit-and-reach test) and HRQoL (36-item Short Form Health Survey) were assessed. RESULTS: Participants with type 2 diabetes had lower mean scores for sit and reach and higher mental component score than control participants. When both groups were categorized regarding their level of physical activity significant differences were found in relation to social function, mental health, general health and vitality between poorly and minimally active patients. CONCLUSIONS: Participants with the greater levels of physical activity also reported better physical fitness which together with the improvement in HRQoL may have clinical implications in the prevention and treatment of type 2 diabetes mellitus.

INTRODUCCIÓN: Los ejercicios físicos son considerados como siendo uno de los componentes para la mejoría de las condiciones de salud en diabéticos tipo 2. Además de eso, algunos estudios han sugerido que niveles más altos de aptitud física también pueden mejorar la calidad de vida relacionada con la salud (CVRS). No obstante, no hay estudios publicados que hayan sido planeados, específicamente, para examinar esta relación. OBJETIVO: El objetivo de este estudio fue evaluar el efecto del nivel de actividades físicas sobre la aptitud física y la CVRS, y determinar si hay diferencias cuando se comparan individuos con y sin diabetes mellitus tipo 2. MÉTODO: Cincuenta y cuatro participantes, con diabetes tipo 2, y 54 participantes, de edades comparables, sin diabetes, fueron voluntarios a fin de participar en este estudio. La aptitud física (prueba de 30 segundos para levantarse de la silla, prueba de caminata de seis minutos y prueba de sentarse y alcanzar algo) y la CVRS (VC-36) fueron evaluadas. RESULTADOS: Los participantes con diabetes tipo 2 presentaron menores puntuaciones en promedio para la prueba de sentarse y alcanzar algo, y una puntuación más alta en componente mental en comparación con los participantes de control. Cuando los dos grupos fueron clasificados con respecto al nivel de actividades físicas, se encontraron diferencias significativas con referencia a función social, salud mental, salud general y vitalidad, entre los pacientes insuficiente y mínimamente activos. CONCLUSIÓN: Los participantes con niveles más altos de prácticas de actividades físicas también mostraron mejor aptitud física, la cual, conjuntamente con las mejorías en la CVRS, puede tener implicaciones clínicas para la prevención y el tratamiento de la diabetes mellitus tipo 2.

Purpose: To determine groups in women with fibromyalgia syndrome (FM) based on symptomatology and determine cardiovascular parameters during treadmill exercise to prescribe them physical activity. Methods: Women (N =32, age =53.3 ± 6.6yr) were assigned into two different groups according to their functional capacity and symptomatology. During incremental treadmill exercise test, exercise intensity was increased until participants achieved volitional exhaustion (VO2max). Expired respiratory gases, ventilator parameters and heart rate (HR) were measured continuously during exercise and RPE was assessed each minute during the test. Results: Peak VO2 values for the group 1 were significantly different than for group 2 (24,9 ± 3,2 ml•kg-1•min-1 (Group 1) and 21,5 ± 2,1 ml•kg-1•min-1(Group 2)) similar ones to the found in other studies with women with FM, altough lower than anther populations without this pathology. On the other hand, if we take into account the VO2VT, we found no significant differences between groups in both trials. We found also differences in all the evaluated parameters. Conclusion: Depending on the level of affectation and the symptomatology of the FM patients, their aerobic capacities were differents; therefore, we are not be able to prescribe physical activity with the same intensity for both groups. According to those results, professionals could prescribe physical activity with a high security and control.

Objetivo: Determinar los principales parámetros cardio-respiratorios de las mujeres con fibromialgia y su clasificación en función del nivel de afectación para una posterior prescripción de actividad física. Método: Una muestra de 32 mujeres (edad ± sd; 53.3 ± 6.6 años) fueron clasificadas en dos grupos experimentales en función de su nivel de afectación y sintomatología; niveles moderado y alto. Ambos grupos se sometieron a dos pruebas de esfuerzo en tapiz rodante separadas una semana en el tiempo. La intensidad del ejercicio se incrementó hasta que los participantes alcanzasen su máxima capacidad (VO2max). Los gases expirados, parámetros ventilatorios y frecuencia cardiaca (FC) se midieron continuamente durante el ejercicio y la valoración subjetiva del esfuerzo (RPE) controlada cada minuto en el test. Resultados: Los valores medios de consumo de oxígeno pico (VO2pico) alcanzados por ambos grupos fueron 24.9 ± 3.2 ml•kg-1•min-1 (Gr1) frente a 21.5 ± 2.1 ml•kg-1•min-1 (Gr2), similares a otros estudios en mujeres con fibromialgia, aunque inferiores a otras poblaciones de referencia. En el resto de parámetros ventilatorios, aún siendo inferiores en el grupo con mayor nivel de afectación, no se muestran diferencias significativas. Conclusiones: Hemos comprobado, como en función del nivel de afectación y la sintomatología de los pacientes con fibromialgia, sus capacidades cardiorrespiratorias son distintas; por tanto, no podremos prescribir un ejercicio con la misma intensidad a mujeres de ambos grupos. En base a estos resultados los profesionales podrán prescribir actividad física con mayor seguridad y control.

The aim of the current study was to determine the relationship between levels of depression and perceived quality of life based on the level of physical activity in patients with fibromyalgia in Seville (Spain). A total of 67 women diagnosed with fibromyalgia voluntarily participated in the study. The level of physical activity was assessed using the International Questionnaire of Physical Activity, the incidence of depression was assessed using the Beck Depression Inventory and their perceived quality of life using the SF-36. Significant differences between physical function and general health based on the depression categories in those with a moderate level of physical activity were found. In addition, high correlations were found between levels of depression and physical functioning (r = -.409, p < .05), general health (r = -.453, p < .05) and mental health (r = -.539, p < .05) among the participants. In conclusion, given the close relationship between depression and the perceived quality of life and the ability of physical activity to modulate these relationships in fibromyalgia patients, professionals should establish prevention strategies based on the promotion of physical activity to help improve health in this population.

El objetivo del presente estudio es determinar la posible relación existente entre los niveles de depresión y la percepción de calidad de vida atendiendo a los niveles de actividad física de pacientes con fibromialgia de la población de Sevilla. Se evaluó el nivel de actividad física en 67 mujeres diagnosticadas de fibromialgia por medio del Cuestionario Internacional de Actividad Física, se valoró la incidencia de la depresión por medio del Inventario de Depresión de Beck y la calidad de vida percibida mediante el cuestionario SF-36. Se reflejaron diferencias significativas en la función física y la salud general entre los diferentes niveles de depresión en aquellos participantes con un nivel de actividad física moderada. Igualmente, se pudo evidenciar una alta correlación entre los niveles de depresión y la función física (r = -.409, p < .05), salud general (r = -.453, p < .05) y salud mental (r = -.539, p < .05) de los pacientes. Como conclusión, queda patente la estrecha relación entre la depresión y la calidad de vida de estos pacientes y la capacidad de la actividad física para modular estas relaciones. Estos resultados permitirán a los profesionales establecer estrategias de prevención, basadas en la promoción de la actividad física, que contribuyan a la mejora de la salud en estas mujeres.