Abstract INTRODUCTION During the pandemic caused by the SARS-CoV-2 virus, some patients who develop severe forms of COVID-19 present thrombotic microangiopathy in the course of the disease’s clinical progression. METHODS Data came from direct patient observation and clinical records. We performed a kidney biopsy and used optical microscopy and immunofluorescence techniques. RESULTS We present the case of a 78-year-old male patient, mestizo, overweight with a history of high blood pressure, ischemic cardiopathy and chronic obstructive pulmonary disease who was first admitted to the hospital due to respiratory symptoms and diarrhea related to COVID-19, from which he recovered. He was subsequently readmitted with symptoms of acute renal dysfunction accompanied by mild anemia and thrombocytopenia; at the same time, he resulted negative for COVID-19 via a real-time polymerase chain reaction test. A kidney biopsy revealed thrombi in glomerular capillaries, acute tubular necrosis, thickening of extraglomerular blood vessel walls, and C3 deposits in the glomerular tufts. CONCLUSIONS We describe a case of thrombotic microangiopathy with kidney biopsy in a patient recovering from COVID-19. Acute renal dysfunction is a form of thrombotic microangiopathy that has been observed in patients recovering from COVID-19.

Abstract Citrus wilt is a disease of recent appearance in the northern area of Veracruz that causes economic losses to producers in the region. The present work aimed to identify the causative agent of this disease and evaluate different fungicides to determine its in vitro sensitivity. A fungus was consistently isolated in plants with wilt symptoms; it was morphologically identified in different culture media and molecularly identified by PCR using the EF1-728F/EF1-986R primers. The fungus was inoculated in three varieties of citrus under greenhouse conditions. The sensitivity test was carried out with the fungicides chlorothalonil, benomyl thiabendazole, prochloraz, and a biological agent (Bacillus subtilis) at different concentrations, plus a negative control. Fusarium sp. (Accession No. MW438335) was morphologically and molecularly identified as the causal agent of vascular wilt in citrus fruits, causing growth retardation, decreased number of roots, wilting of the apical bud, and necrosis in the vascular system of the three varieties inoculated. The most effective fungicides in inhibiting mycelial growth were thiabendazole, prochloraz, and the biological agent Bacillus subtilis.

Resumen La marchitez y muerte de los cítricos es una enfermedad de reciente aparición en la zona norte de Veracruz, que ocasiona pérdidas económicas a los productores de la región. Por lo anterior, el objetivo de este trabajo fue identificar al agente causal de esta enfermedad y evaluar diferentes fungicidas para determinar su sensibilidad in vitro. De manera consistente se aisló un hongo en plantas con síntomas de marchitez, se identificó morfológicamente en diferentes medios de cultivo y molecularmente con los iniciadores EF1-728F/EF1-986R mediante PCR. El hongo se inoculó en tres variedades de cítricos bajo condiciones de invernadero. La prueba de sensibilidad se realizó con los fungicidas clorotalonil, benomil tiabendazol, procloraz y un biológico (Bacillus subtilis) a diferentes concentraciones, más un testigo negativo. Se identificó morfológica y molecularmente a Fusarium sp. (No. de accesión MW438335) como agente causal de la marchitez vascular de los cítricos, mismo que ocasionó retraso de crecimiento, disminución de cantidad de raíces, marchitez del brote apical y necrosis en el sistema vascular en las tres variedades inoculadas. Los fungicidas con mayor eficacia en inhibir el crecimiento micelial fueron tiabendazol, procloraz y el biológico Bacillus subtilis.

Abstract Objective: This study included the analysis of the perceptions of entrepreneurs in the industrial sector of Hermosillo, Sonora Mexico, regarding the assessment of the skills they develop and apply in their activity. Methodology: 52 entrepreneurs were interviewed and eight skills were evaluated: 1) Creativity, 2) Initiative and responsibility, 3) Planning, 4) Management and commitment, 5) Social responsibility and teamwork 6) Attitude to face change, 7) Self-confidence and 8) Communication. Results: The results showed differences in terms of skill ratings, and their correlation with each other, evidencing that Management and commitment skills have a negative correlation with the rest of the variables. Limitations: The interviewees were reluctant to share information. Conclusions: The group of entrepreneurs studied must become aware of the importance of the ability of Management and commitment in achieving the objectives of the companies, which makes it a challenge or opportunity area for the consolidation of the entrepreneurial profile of the subjects studied.

Resumen Objetivo: El presente estudio comprendió el análisis de las percepciones de los emprendedores del sector industrial de Hermosillo, Sonora México, con respecto a la valoración de las habilidades que desarrolla y aplica en su actividad. Metodología: Se entrevistaron 52 emprendedores y se evaluaron ocho habilidades: 1) Creatividad, 2) Iniciativa y responsabilidad, 3) Planificación, 4) Gestión y compromiso, 5) Responsabilidad social y trabajo en equipo 6) Actitud para enfrentar el cambio, 7) Autoconfianza y 8) Comunicación. Resultados: Los resultados arrojaron diferencias en cuanto a las valoraciones de las habilidades, y su correlación entre sí, evidenciando que la habilidad de Gestión y compromiso tienen una correlación negativa con el resto de las variables. Limitaciones: Las personas entrevistadas se mostraron reticentes al momento de compartir información. Conclusiones: El grupo de emprendedores estudiados debe de cobrar conciencia sobre la importancia de la habilidad de Gestión y compromiso en el logro de los objetivos de las empresas, lo que la convierte en un reto o área de oportunidad para la consolidación del perfil emprendedor de los sujetos estudiados.

Abstract: Introduction: There are few studies on overlapping Functional Gastrointestinal Disorders (FGIDs). Objective: To describe the prevalence and possible risk factors in Latin American children (Latam) to present overlapping FGIDs. Patients and Method: Prevalence study in Latam schoolchildren bet ween 8-18 years of age. Sociodemographic variables were included; the Rome III Criteria in Spanish were used, and overlapping FGIDs were considered when two, three or four and more FGIDs were presented in the same child. The statistical analysis included Student’s T-test, chi-square test, Fisher’s exact test, univariate and multivariate analysis, and calculation of ORs and 95% CI, being considered a significant p < 0.05. Results: 6,193 Latam children were analyzed (11.8 ± 2.2 years, 62.2% between 8-12 years of age, 50.4% girls, 68.0% public school), and 23.4% with a diagnosis of some kind of FGIDs. There was overlap of FGIDs in the same child, in 8.4% (5.5% with 2 FGIDs, 2.1% with 3 FGIDs and 0.9% with 4 or more FGIDs), the main overlaps were irritable bowel syndrome (IBS) + functional abdominal pain (FAP) (2.6%), and IBS + FAP + functional constipation (1.1%). There was predominance of the female gender. Conclusion: There is a low prevalence of overlapping FGIDs in Latam schoolchildren and adolescents, with a predominance in females and of very variable pre sentation.

Resumen: Introducción: Hay pocos estudios sobre Desórdenes Gastrointestinales Funcionales superpuestos (DGFs-s). Objetivo: Describir la prevalencia y posibles factores de riesgo en niños Latinoamericanos (Latam) para presentar DGFs-s. Pacientes y Método: Estudio de prevalencia en niños escolares La tam entre 8-18 años. Se incluyeron variables sociodemográficas; se utilizaron los Criterios de Roma III en español, y se consideró DGFs-s cuando se presentaron 2, 3 o 4 y más DGFs en un mismo niño. El análisis estadístico incluyó t de student, chi cuadrado, prueba exacta de Fisher, análisis uni y multivariados y cálculo de los ORs e IC95%, siendo considerada una p < 0,05 significativa. Resul tados: Fueron analizados 6193 niños Latam (11,8 ± 2,2 años; 62,2% entre 8-12 años; 50,4% niñas; 68,0% colegio público), con diagnóstico de algún DGFs del 23,4%. Hubo superposición de DGFs en un mismo niño, en 8,4% (5,5% con 2 DGFs; 2,1% con 3 DGFs y 0,9% con 4 o más DGFs), siendo las principales superposiciones el Síndrome de intestino irritable (SII) + Dolor abdominal funcio nal (DAF) (2,6%) y el SII + DAF + Estreñimiento funcional (1,1%). Hubo predomino del género femenino. Conclusión: Hay una baja prevalencia de DGFs-s en escolares y adolescentes Latam, con predominio en el sexo femenino y de presentación muy variable.