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[SciELO Preprints] - Guidelines on the Diagnosis and Treatment of Hypertrophic Cardiomyopathy – 2024
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Fernandes, Fabio Simões, Marcus V. Correia, Edileide de Barros Marcondes-Braga, Fabiana G. Coelho-Filho, Otavio Rizzi Mesquita, Cláudio Tinoco Mathias-Junior, Wilson Rochitte, Carlos Eduardo Ramires, Felix José Alvarez Alves, Silvia Marinho Martins Montera, Marcelo Westerlund Lopes, Renato Delascio Oliveira-Junior, Mucio Tavares Scolari, Fernando L. Avila, Walkiria Samuel Canesin, Manoel Fernandes Bacal, Fernando Bocchi, Edimar Alcides Moura, Lídia Ana Zytynski Saad, Eduardo Benchimol Scanavacca, Mauricio I. Valdigem, Bruno Pereira Cano , Manuel Nicolas Abizaid , Alexandre Ribeiro, Henrique Barbosa Lemos-Neto, Pedro Alves Ribeiro, Gustavo Calado de Aguiar Jatene, Fabio Biscegli Dias, Ricardo Ribeiro Beck-da-Silva, Luis Rohde, Luis Eduardo P. Bittencourt, Marcelo Imbroinise Pereira, Alexandre Krieger, José Eduardo Villacorta, Humberto Martins, Wolney de Andrade Figueiredo-Neto, José Albuquerque de Cardoso , Juliano Novaes Pastore, Carlos Alberto Jatene, Ieda Biscegli Tanaka, Ana Cristina Sayuri Hotta, Viviane Tiemi Romano, Minna Moreira Dias Albuquerque, Denilson Campos de Mourilhe-Rocha, Ricardo Hajjar, Ludhmila Abrahão Brito, Fabio Sandoli de Caramelli , Bruno Calderaro, Daniela Farsky, Pedro Silvio Colafranceschi , Alexandre Siciliano Pinto, Ibraim Masciarelli Vieira , Marcelo Luiz Campos Danzmann, Luiz Claudio Barberato , Silvio Henrique Mady, Charles Martinelli-Filho, Martino Torbey , Ana Flavia Malheiros Schwartzmann, Pedro Vellosa Macedo, Ariane Vieira Scarlatelli Ferreira , Silvia Moreira Ayub Schmidt, Andre Melo , Marcelo Dantas Tavares de Lima-Filho, Moysés Oliveira Sposito, Andrei C. Brito, Flavio de Souza Biolo, Andreia Madrini-Junior, Vagner Rizk, Stéphanie Itala Mesquita, Evandro Tinoco

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Publication date: 2024-04-08

Abstract: Pt Es En

A cardiomiopatia hipertrófica (CMH) é uma forma de doença do músculo cardíaco de causa genética, caracterizada pela hipertrofia das paredes ventriculares. O diagnóstico requer detecção por métodos de imagem (Ecocardiograma ou Ressonância Magnética Cardíaca) de qualquer segmento da parede do ventrículo esquerdo com espessura > 15 mm, sem outra causa provável. A análise genética permite identificar mutações de genes codificantes de diferentes estruturas do sarcômero responsáveis pelo desenvolvimento da CMH em cerca de 60% dos casos, permitindo o rastreio de familiares e aconselhamento genético, como parte importante do manejo dos pacientes e familiares. Vários conceitos sobre a CMH foram recentemente revistos, incluindo sua prevalência de 1 em 250 indivíduos, não sendo, portanto, uma doença rara, mas subdiagnosticada. A vasta maioria dos pacientes é assintomática. Naqueles sintomáticos, a obstrução do trato de saída do ventrículo esquerdo (OTSVE) é o principal distúrbio responsável pelos sintomas, devendo-se investigar a sua presença em todos os casos. Naqueles em que o ecocardiograma em repouso ou com Manobra de Valsalva não detecta gradiente intraventricular significativo (> 30 mmHg), devem ser submetidos à ecocardiografia com esforço físico para detecção da OTSVE.   Pacientes com sintomas limitantes e grave OTSVE, refratários ao uso de betabloqueadores e verapamil, devem receber terapias de redução septal ou uso de novas drogas inibidoras da miosina cardíaca. Por fim, os pacientes adequadamente identificados com risco aumentado de morta súbita podem receber medida profilática com implante de cardiodesfibrilador implantável (CDI).

La miocardiopatía hipertrófica (MCH) es una forma de enfermedad cardíaca de origen genético, caracterizada por el engrosamiento de las paredes ventriculares. El diagnóstico requiere la detección mediante métodos de imagen (Ecocardiograma o Resonancia Magnética Cardíaca) que muestren algún segmento de la pared ventricular izquierda con un grosor > 15 mm, sin otra causa probable. El análisis genético permite identificar mutaciones en genes que codifican diferentes estructuras del sarcómero responsables del desarrollo de la MCH en aproximadamente el 60% de los casos, lo que permite el tamizaje de familiares y el asesoramiento genético, como parte importante del manejo de pacientes y familiares. Varios conceptos sobre la MCH han sido revisados recientemente, incluida su prevalencia de 1 entre 250 individuos, por lo tanto, no es una enfermedad rara, sino subdiagnosticada. La gran mayoría de los pacientes son asintomáticos. En los casos sintomáticos, la obstrucción del tracto de salida ventricular izquierdo (TSVI) es el trastorno principal responsable de los síntomas, y su presencia debe investigarse en todos los casos. En aquellos en los que el ecocardiograma en reposo o la maniobra de Valsalva no detecta un gradiente intraventricular significativo (> 30 mmHg), deben someterse a ecocardiografía de esfuerzo para detectar la obstrucción del TSVI. Los pacientes con síntomas limitantes y obstrucción grave del TSVI, refractarios al uso de betabloqueantes y verapamilo, deben recibir terapias de reducción septal o usar nuevos medicamentos inhibidores de la miosina cardíaca. Finalmente, los pacientes adecuadamente identificados con un riesgo aumentado de muerte súbita pueden recibir medidas profilácticas con el implante de un cardioversor-desfibrilador implantable (CDI).

Hypertrophic cardiomyopathy (HCM) is a form of genetically caused heart muscle disease, characterized by the thickening of the ventricular walls. Diagnosis requires detection through imaging methods (Echocardiogram or Cardiac Magnetic Resonance) showing any segment of the left ventricular wall with a thickness > 15 mm, without any other probable cause. Genetic analysis allows the identification of mutations in genes encoding different structures of the sarcomere responsible for the development of HCM in about 60% of cases, enabling screening of family members and genetic counseling, as an important part of patient and family management. Several concepts about HCM have recently been reviewed, including its prevalence of 1 in 250 individuals, hence not a rare but rather underdiagnosed disease. The vast majority of patients are asymptomatic. In symptomatic cases, obstruction of the left ventricular outflow tract (LVOT) is the primary disorder responsible for symptoms, and its presence should be investigated in all cases. In those where resting echocardiogram or Valsalva maneuver does not detect significant intraventricular gradient (> 30 mmHg), they should undergo stress echocardiography to detect LVOT obstruction. Patients with limiting symptoms and severe LVOT obstruction, refractory to beta-blockers and verapamil, should receive septal reduction therapies or use new drugs inhibiting cardiac myosin. Finally, appropriately identified patients at increased risk of sudden death may receive prophylactic measure with implantable cardioverter-defibrillator (ICD) implantation.

https://doi.org/10.1590/SciELOPreprints.8394

Reflectance confocal microscopy - Consensus terminology glossary in Brazilian Portuguese for normal skin, melanocytic and non-melanocytic lesions skin nonmelanocytic non
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Braga, Juliana Casagrande Tavoloni

; Barcaui, Carlos B.

; Pinheiro, Ana Maria

; Sortino, Ana Maria Fagundes

; Abdalla, Cristina Martinez Zugaib

; Campos-do-Carmo, Gabriella

; Rezze, Gisele Gargantini

; Pineiro-Maceira, Juan

; Rocha, Lilian Licarião

; Maia, Marcus

; Sá, Bianca Costa Soares de

Anais Brasileiros de Dermatologia

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jan 2024, Volume 99 N. 1 Pages 100 - 110

Abstract: En | Text: En | PDF: En

Abstract Background: Currently, there is no uniform and official terminology in Portuguese for reflectance confocal microscopy analysis, despite the increasing number of Brazilian dermatologists using this new tool. Objective: To present the terminology in Brazilian Portuguese for the description of reflectance confocal microscopy and establish the first Brazilian consensus on terms related to normal skin and cutaneous tumors. Methods: 10 Brazilian specialists from different institutions and states of Brazil were selected to evaluate the best corresponding terms in Portuguese for normal skin, melanocytic and non-melanocytic tumors. The terms used were translated from international consensuses in the English language. The modified Delphi method was used to create the consensus in 3 steps. Results: The terms considered the most appropriate in the Portuguese language to describe the findings of normal skin, melanocytic and non-melanocytic lesions in the reflectance confocal microscopy analysis were presented. Study limitations: The limitations of the present study include the number of participants and limited regional representation (only two of the five Brazilian regions were represented). Conclusion: This Brazilian consensus represents an opportunity for dermatologists and physicians specializing in cutaneous oncology to become familiar with reflectance confocal microscopy, propagating the technique in clinical and research environments to stimulate national and international publications on this subject. Background Currently tool Objective tumors Methods 1 nonmelanocytic non steps Results presented only represented. represented . represented) Conclusion subject

https://doi.org/10.1016/j.abd.2023.05.001

Síndrome pós-COVID-19 entre hospitalizados por COVID-19: estudo de coorte após 6 e 12 meses da alta hospitalar
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Rocha, Roseany Patricia Silva

; Andrade, Amanda Cristina de Souza

; Melanda, Francine Nesello

; Muraro, Ana Paula

Cadernos de Saúde Pública

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2024, Volume 40 N. 2 elocation e00027423

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

A síndrome pós-COVID-19 é um termo usado para descrever um conjunto diversificado de sintomas que persistem por mais de 12 semanas da infecção diagnosticada. O objetivo deste estudo foi analisar a síndrome pós-COVID-19 entre hospitalizados por COVID-19 após 6 e 12 meses da alta hospitalar. Trata-se de estudo de coorte ambidirecional, realizado com indivíduos que receberam alta em três dos principais hospitais da capital de Mato Grosso, Brasil, entre outubro e dezembro de 2021 e janeiro e março de 2022. Após coleta de dados em prontuários, os indivíduos foram entrevistados por telefone após 6 e 12 meses da alta hospitalar, sendo questionados sobre a presença de sintomas persistentes ou novos, para a avaliação de sua frequência segundo características sociodemográficas, econômicas, relativas à internação e condições de saúde. Dos 277 prontuários avaliados, 259 pacientes foram elegíveis para o estudo, 190 aos seis meses e 160 após 12 meses da alta hospitalar. Aos seis meses, 59% eram mulheres, 40% com 60 anos ou mais de idade e 87,4% referiram a presença de pelo menos um sintoma. Aos 12 meses, 58,7% eram mulheres, 37,5% com 30 a 49 anos e 67,5% referiram a presença de pelo menos um sintoma. A fadiga foi o sintoma mais comum após 6 e 12 meses de alta hospitalar (55,3% e 40,6%, respectivamente), seguido de problemas de memória (36,8%; 20%) e perda de cabelo (26,8%; 11,2%). Foi maior a prevalência de síndrome pós-COVID-19 entre indivíduos de maior faixa etária, menor renda, hipertensos, diabéticos e com maior gravidade durante a internação. Os fatores de risco da síndrome pós-COVID-19 contribuem para a compreensão dos efeitos a longo prazo e da importância do acompanhamento após a fase aguda da doença.

Post-COVID-19 syndrome involves a variety of symptoms that last more than 12 weeks after COVID diagnosis. This study aimed to analyze post-COVID-19 syndrome among hospitalized COVID-19 patients 6 and 12 months after hospital discharge. This is an ambidirectional cohort study conducted with individuals who were discharged from three main hospitals in the capital of Mato Grosso State, Brazil, between October and December 2021 and January and March 2022. After data collection from medical records, the individuals were interviewed by telephone 6 and 12 months after hospital discharge, when they were asked about the presence of ongoing or new symptoms and when symptom frequency was evaluated according to sociodemographic and economic characteristics hospitalization, and health conditions. Of all 277 medical records evaluated, 259 patients were eligible to participate in the study, 190 patients six months after discharge and 160 patients 12 months after hospital discharge. At six months, 59% were female patients, 40% were aged 60 years or older, and 87.4% reported at least one symptom. At 12 months, 58.7% were female patients, 37.5% were aged 30 to 49 years, and 67.5% reported at least one symptom. Fatigue was the most common symptom 6 and 12 months after hospital discharge (55.3% and 40.6%, respectively), followed by memory problems (36.8%; 20%), and hair loss (26.8%; 11.2%). The prevalence of post-COVID-19 syndrome was higher among patients of older age, lower income, with hypertension, diabetes, and more severe infection during hospitalization. The risk factors for post-COVID-19 syndrome help understand the long-term effects and the importance of monitoring after the acute phase of the disease.

El síndrome post-COVID-19 es un término utilizado para describir un conjunto diversificado de síntomas que persisten durante más de 12 semanas de la infección diagnosticada. El objetivo fue analizar el síndrome post-COVID-19 entre hospitalizados por COVID-19 tras 6 y 12 meses del alta hospitalaria. Se trata de un estudio de cohorte ambidireccional, realizado con individuos que fueron dados de alta en tres de los principales hospitales de la capital de Mato Grosso, Brasil, entre octubre y diciembre de 2021 y enero y marzo de 2022. Tras recolectar los datos en registros médicos, se entrevistaron los individuos por teléfono tras 6 y 12 meses del alta hospitalaria, cuestionándoles sobre la presencia de síntomas persistentes o nuevos y evaluando su frecuencia conforme las características sociodemográficas, económicas, relacionadas con la hospitalización y condiciones de salud. De los 277 registros médicos evaluados, se eligieron 259 pacientes para el estudio, 190 a los 6 meses y 160 tras 12 meses del alta hospitalaria. A los 6 meses, el 59% eran mujeres, el 40% tenían 60 años o más y el 87,4% refirieron la presencia de al menos un síntoma. A los 12 meses, el 58,7% eran mujeres, el 37,5% tenían entre 30 y 49 años y el 67,5% refirieron la presencia de al menos un síntoma. La fatiga fue el síntoma más común tras 6 y 12 meses del alta hospitalaria (el 55,3% y el 40,6%, respectivamente), seguido de los problemas de memoria (el 36,8% y el 20%) y caída del pelo (el 26,8% y el 11,2%). La prevalencia de síndrome post-COVID-19 fue más alta entre los individuos de mayor edad, menor renta, hipertensos, diabéticos y con mayor gravedad durante la hospitalización. Los factores de riesgo del síndrome post-COVID-19 contribuyen para la comprensión de los efectos a largo plazo y de la importancia del seguimiento tras la fase aguda de la enfermedad.

https://doi.org/10.1590/0102-311xpt027423

Síndrome pós-COVID-19 entre hospitalizados por COVID-19: estudo de coorte após 6 e 12 meses da alta hospitalar pósCOVID19 pósCOVID pós COVID 19 pós-COVID-1 COVID19 COVID-19 1 pósCOVID1 pós-COVID- COVID1 COVID-1 pós-COVID COVID-
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Rocha, Roseany Patricia Silva

; Andrade, Amanda Cristina de Souza

; Melanda, Francine Nesello

; Muraro, Ana Paula

Cadernos de Saúde Pública

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2024, Volume 40 N. 2 elocation e00027423

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/0102-311xpt027423

Translation and measurement properties of the Portuguese-Brazil version of the Hammersmith Infant Neurological Examination (HINE-Br) PortugueseBrazil Portuguese Brazil HINEBr HINE Br (HINE-Br
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Furtado, Michelle Alexandrina dos Santos

; Leite, Hércules Ribeiro

; Klettenberg, Matheus Rocha Pereira

; Rodrigues, Victor Alves

; Ferreira, Lisiane Seguti

; Marques, Melina Rodero

; Cavalcante, Isadora de Oliveira

; Santos, Tamires Saboia

; Souza, Tathiana Ghisi de

; Mendonça, Ayrles Silva Gonçalves Barbosa

; Camargos, Ana Cristina Resende

; Ayupe, Kênnea Martins Almeida

Revista Paulista de Pediatria

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2024, Volume 42 elocation e2023105

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Traduzir o Hammersmith Infant Neurological Examination (HINE) para o português brasileiro e analisar a confiabilidade da versão traduzida em lactentes brasileiros. Métodos: Estudo metodológico, aprovado por Comitê de Ética, realizado entre junho de 2020 e maio de 2021. O HINE é um exame clínico neurológico padronizado, utilizado para detecção precoce de paralisia cerebral. A seção quantitativa, “exame neurológico”, contém 26 itens pontuados de 0 a 3, divididos em 5 categorias: função dos nervos cranianos; postura; movimentos; tônus muscular e reflexos; e reações. A tradução do HINE seguiu quatro etapas: tradução; síntese; retrotradução; e avaliação por um comitê de especialistas. Dois examinadores independentes avaliaram 43 lactentes, entre 3 e 22 meses, utilizando a versão HINE-Br (versão em português brasileiro), para verificar sua confiabilidade. A consistência interna foi verificada pelo coeficiente Alpha de Cronbach e a confiabilidade interexaminadores pelo coeficiente de correlação intraclasse (CCI). Resultados: A versão traduzida foi semelhante à versão original e poucos ajustes semânticos e idiomáticos foram necessários. Encontrou-se consistência interna adequada (Apha=0,91) para os 26 itens do HINE-Br, bem como forte confiabilidade interexaminadores para o escore total (CCI2,1=0,95) e também para as cinco categorias (CCI2,1=0,83–0,95). Conclusões: O HINE-Br apresenta índices adequados de consistência interna e confiabilidade interexaminadores, podendo ser utilizada para avaliação de crianças com risco de apresentar paralisia cerebral, entre 3 e 24 meses de idade, por pediatras e fisioterapeutas infantis. Objetivo (HINE brasileiros Métodos metodológico Ética 202 2021 padronizado cerebral quantitativa neurológico, , neurológico” 2 cranianos postura movimentos reflexos reações etapas síntese retrotradução especialistas 4 HINEBr Br brasileiro, brasileiro) CCI. CCI . (CCI) Resultados necessários Encontrouse Encontrou se Apha=0,91 Apha091 Apha 91 (Apha=0,91 HINEBr, Br, CCI2,1=0,95 CCI21095 CCI2 1 95 (CCI2,1=0,95 CCI2,1=0,83–0,95. CCI21083095 CCI2,1=0,83–0,95 83 (CCI2,1=0,83–0,95) Conclusões idade infantis 20 (CCI Apha=0,9 Apha09 9 (Apha=0,9 CCI2,1=0,9 CCI2109 (CCI2,1=0,9 CCI2108309 CCI2,1=0,83–0,9 8 (CCI2,1=0,83–0,95 Apha=0, Apha0 (Apha=0, CCI2,1=0, CCI210 (CCI2,1=0, CCI210830 CCI2,1=0,83–0, (CCI2,1=0,83–0,9 Apha=0 (Apha=0 CCI2,1=0 CCI21 (CCI2,1=0 CCI21083 CCI2,1=0,83–0 (CCI2,1=0,83–0, Apha= (Apha= CCI2,1= (CCI2,1= CCI2108 CCI2,1=0,83– (CCI2,1=0,83–0 (Apha CCI2,1 (CCI2,1 CCI2,1=0,83 (CCI2,1=0,83– CCI2, (CCI2, CCI2,1=0,8 (CCI2,1=0,83 (CCI2 (CCI2,1=0,8

ABSTRACT Objective: The current study aimed to translate the Hammersmith Infant Neurological Examination (HINE) into Brazilian Portuguese and analyze the reliability of the translated version for a population of Brazilian infants. Methods: This was a methodological study, approved by the Ethics Committee, carried out between June 2020 and May 2021. HINE is a standardized clinical neurological examination used for the early detection of cerebral palsy. The quantitative section, “neurological examination”, contains 26 items scored from 0 to 3 points, divided into five categories: cranial nerve function, posture, movements, muscle tone and reflexes, and reactions. The HINE translation followed four steps: translation, synthesis, back-translation, and evaluation by an expert committee. To verify the reliability of the HINE-Br (Portuguese-Brazil version) two independent examiners evaluated 43 infants, between 3 and 22 months of age. Internal consistency was verified by Cronbach’s Alpha coefficient and interrater reliability by the intraclass correlation coefficient (ICC). Results: The translated version was similar to the original version and a few semantic and idiomatic adjustments were necessary. Appropriate internal consistency (Alpha=0.91) was found for the 26 items of the HINE-Br, as well as strong interrater reliability for the total score (ICC2.1=0.95), and also for the five categories (ICC2.1=0.83–0.95). Conclusions: The HINE-Br presents adequate rates of internal consistency and interrater reliability, and can be used for the evaluation of children at risk for cerebral palsy, between 3 and 24 months of age, by pediatricians and pediatric physical therapists. Objective (HINE infants Methods Committee 202 2021 palsy section examination, , examination” 2 points function posture movements reflexes reactions steps synthesis backtranslation, backtranslation back back-translation committee HINEBr Br PortugueseBrazil Brazil 4 age Cronbachs Cronbach s ICC. ICC . (ICC) Results necessary Alpha=0.91 Alpha091 91 (Alpha=0.91 HINEBr, Br, ICC2.1=0.95, ICC21095 ICC2.1=0.95 ICC2 1 95 (ICC2.1=0.95) ICC2.1=0.83–0.95. ICC21083095 ICC2.1=0.83–0.95 83 (ICC2.1=0.83–0.95) Conclusions therapists 20 (ICC Alpha=0.9 Alpha09 9 (Alpha=0.9 ICC2109 ICC2.1=0.9 (ICC2.1=0.95 ICC2108309 ICC2.1=0.83–0.9 8 (ICC2.1=0.83–0.95 Alpha=0. Alpha0 (Alpha=0. ICC210 ICC2.1=0. (ICC2.1=0.9 ICC210830 ICC2.1=0.83–0. (ICC2.1=0.83–0.9 Alpha=0 (Alpha=0 ICC21 ICC2.1=0 (ICC2.1=0. ICC21083 ICC2.1=0.83–0 (ICC2.1=0.83–0. Alpha= (Alpha= ICC2.1= (ICC2.1=0 ICC2108 ICC2.1=0.83– (ICC2.1=0.83–0 (Alpha ICC2.1 (ICC2.1= ICC2.1=0.83 (ICC2.1=0.83– ICC2. (ICC2.1 ICC2.1=0.8 (ICC2.1=0.83 (ICC2. (ICC2.1=0.8 (ICC2

https://doi.org/10.1590/1984-0462/2024/42/2023105

EFFECT OF THE TRANSITION PROGRAM ON SELF-CARE OF PATIENTS WITH HEART FAILURE: A RANDOMIZED CLINICAL TRIAL SELFCARE SELF CARE FAILURE
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Tinoco, Juliana de Melo Vellozo Pereira

; Padua, Bruna Lins Rocha de

; Souza, Beatriz Paiva e Silva de

; Guimarães, Tereza Cristina Felippe

; Mesquita, Evandro Tinoco

; Cavalcanti, Ana Carla Dantas

Texto & Contexto - Enfermagem

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2024, Volume 33 elocation e20230213

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: analisar o efeito do cuidado de transição no autocuidado, qualidade de vida e conhecimento da doença de pacientes hospitalizados com insuficiência cardíaca. Método: ensaio clínico randomizado cego com 74 pacientes com insuficiência cardíaca em dois hospitais quaternários do Rio de Janeiro-RJ, entre dezembro de 2017 e fevereiro de 2020. O grupo intervenção recebeu cuidados de transição com gerenciamento educativo por enfermeira, à beira do leito, desde a admissão até a alta hospitalar e consulta telefônica por 30 dias após a alta. O grupo controle recebeu acompanhamento usual. Os desfechos primários incluíram habilidades de manutenção, manejo e confiança no autocuidado, e os desfechos secundários, qualidade de vida e conhecimento da doença. Ambos foram avaliados por questionários validados para uso no Brasil. Os dados foram analisados pelo ANOVA de medidas repetidas. Resultados: o grupo intervenção apresentou maiores escores para manutenção (74,3 vs44,2; p<0,001) e confiança do autocuidado (79,3 vs56,4; p<0,001) e conhecimento da doença (41,3 vs27,5; p<0,001) e menores escores de qualidade de vida (42,1 vs64,5; p<0,001) em 30 dias após a alta. Conclusão: o cuidado de transição foi efetivo na melhora da qualidade de vida, conhecimento da doença, manutenção e confiança no autocuidado. Estudo registrado no Registro Brasileiro de Ensaios Clínicos, sob o número RBR-2dpc6b. Objetivo Método 7 JaneiroRJ, JaneiroRJ Janeiro RJ, RJ Janeiro-RJ 201 2020 enfermeira leito 3 usual secundários Brasil repetidas Resultados 74,3 743 (74, vs44,2 vs442 vs vs44 2 p<0,001 p0001 p 0 001 79,3 793 79 (79, vs56,4 vs564 vs56 4 41,3 413 41 (41, vs27,5 vs275 vs27 5 42,1 421 42 1 (42, vs64,5 vs645 vs64 Conclusão Clínicos RBR2dpc6b. RBR2dpc6b RBRdpcb RBR 2dpc6b. 2dpc6b dpc b RBR-2dpc6b 20 202 74, (74 vs44, vs4 p<0,00 p000 00 79, (79 vs56, vs5 41, (41 vs27, vs2 42, (42 vs64, vs6 dpcb (7 p<0,0 p00 (4 ( p<0, p0 p<0 p<

ABSTRACT Objective: analyze the effect of transitional care on self-care, quality of life and knowledge of disease of patients admitted with heart failure. Method: this is a blind randomized clinical trial with 74 patients with heart failure in two quaternary hospitals in Rio de Janeiro-RJ between December 2017 and February 2020. The intervention group received transitional care with educational management by a nurse at the bedside from admission until hospital discharge and telephone consultation for 30 days after discharge. The control group received usual follow-up. The primary outcomes included maintenance skills, management and confidence in self-care, and the secondary outcomes included quality of life and knowledge of disease. Both were assessed using questionnaires validated for use in Brazil. Data were analyzed by repeated measures ANOVA. Results: the intervention group had higher scores for maintenance (74.3 vs 44.2; p<0.001) and self-care confidence (79.3 vs 56.4; p<0.001) and knowledge of disease (41.3 vs 27.5; p<0.001) and lower quality of life scores (42.1 vs 64.5; p<0.001) 30 days after discharge. Conclusion: transitional care was effective in improving quality of life, knowledge of disease, maintenance and confidence in self-care. This study was registered in the Brazilian Clinical Trials Registry, under RBR-2dpc6b. Objective selfcare, selfcare self care, Method 7 JaneiroRJ Janeiro RJ 201 2020 3 followup. followup follow up. up follow-up skills Brazil ANOVA Results 74.3 743 (74. 44.2 442 44 2 p<0.001 p0001 p 0 001 79.3 793 79 (79. 56.4 564 56 4 41.3 413 41 (41. 27.5 275 27 5 42.1 421 42 1 (42. 64.5 645 64 Conclusion selfcare. care. Registry RBR2dpc6b. RBR2dpc6b RBRdpcb RBR 2dpc6b. 2dpc6b dpc b RBR-2dpc6b 20 202 74. (74 44. p<0.00 p000 00 79. (79 56. 41. (41 27. 42. (42 64. 6 dpcb (7 p<0.0 p00 (4 ( p<0. p0 p<0 p<

RESUMEN Objetivo: analizar el efecto de los cuidados transicionales sobre el autocuidado, la calidad de vida e y el conocimiento de la enfermedad de pacientes hospitalizados con insuficiencia cardíaca. Método: ensayo clínico aleatorio ciego con 74 pacientes con insuficiencia cardíaca en dos hospitales cuaternarios de Río de Janeiro-RJ entre diciembre de 2017 y febrero de 2020. El grupo de intervención recibió cuidados de transición con manejo educativo por parte de una enfermera al lado de la cama desde el ingreso hasta el alta hospitalaria y Consulta telefónica durante 30 días después del alta. El grupo de control recibió el seguimiento habitual. Los resultados primarios incluyeron habilidades de mantenimiento, gestión y confianza en el autocuidado, y los resultados secundarios incluyeron calidad de vida y conocimiento de la enfermedad. Ambos fueron evaluados mediante cuestionarios validados para su uso en Brasil. Los datos fueron analizados mediante ANOVA de medidas repetidas. Resultados: el grupo de intervención tuvo puntuaciones más altas en mantenimiento (74,3 vs 44,2; p<0,001) y confianza en el autocuidado (79,3 vs 56,4; p<0,001) y conocimiento de la enfermedad (41,3 vs 27,5; p<0,001)y puntuaciones de calidad de vida más bajas (42,1 frente a 64,5; p<0,001) 30 días después del alta. Conclusión: la atención de transición fue eficaz para mejorar la calidad de vida, el conocimiento de la enfermedad, el mantenimiento y la confianza en el autocuidado. Estudio inscrito en el Registro Brasileño de Ensayos Clínicos, con el número RBR-2dpc6b. Objetivo Método 7 JaneiroRJ Janeiro RJ 201 2020 3 habitual Brasil repetidas Resultados 74,3 743 (74, 44,2 442 44 2 p<0,001 p0001 p 0 001 79,3 793 79 (79, 56,4 564 56 4 41,3 413 41 (41, 27,5 275 27 5 p<0,001y p0001y py 42,1 421 42 1 (42, 64,5 645 64 Conclusión Clínicos RBR2dpc6b. RBR2dpc6b RBRdpcb RBR 2dpc6b. 2dpc6b dpc b RBR-2dpc6b 20 202 74, (74 44, p<0,00 p000 00 79, (79 56, 41, (41 27, 001y 42, (42 64, 6 dpcb (7 p<0,0 p00 (4 ( p<0, p0 p<0 p<

https://doi.org/10.1590/1980-265x-tce-2023-0213en

Diretivas antecipadas de vontade como temática da educação médica
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Bastos, Thalita da Rocha

; Macedo, Letícia Fonseca

; Silva, Yasmim Carmine Brito da

; Braga, Thaisy Luane Gomes Pereira

; Salgado, Renan Soeiro

; Soeiro, Ana Cristina Vidigal

Revista Bioética

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2024, Volume 32 elocation e3696PT

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo A pesquisa investigou o conhecimento de professores e alunos do internato médico acerca das diretivas antecipadas de vontade, que visam assegurar os direitos dos pacientes de registrar sua preferência pelos cuidados médicos a que serão submetidos quando estiverem incapacitados de tomar decisões. Trata-se de estudo transversal, descritivo, observacional, com abordagem majoritariamente quantitativa, que contou com a participação de 30 professores do curso de medicina e 121 acadêmicos de medicina vinculados a duas instituições de ensino localizadas em Belém/PA. Os resultados revelaram lacunas no conhecimento a respeito do tema, apontando a necessidade de uma abordagem mais aprofundada durante a formação e a prática médica. Conclui-se que é necessário intensificar a divulgação de diretivas antecipadas de vontade no âmbito do ensino médico, de forma a favorecer a autonomia e o compartilhamento das decisões. decisões Tratase Trata se transversal descritivo observacional quantitativa 3 12 BelémPA Belém PA Belém/PA tema médica Concluise Conclui 1

Abstract This study investigated the knowledge of medical professors and students during internship regarding advance directives, a device that aims to ensure the right of patients to record their preference for medical care they will be subject to when incapable of making decisions. This is a cross-sectional, descriptive and observational study with a mostly quantitative approach, of which participated 30 professors and 121 medical students from two teaching institutions in Belém/PA. The results identified gaps in the knowledge about the topic, pointing to the need for a deeper approach during medical training and practice. It is concluded that the divulging of advance directives in medical training should be more intense to favor autonomy and share decision making. decisions crosssectional, crosssectional cross sectional, sectional cross-sectional 3 12 BelémPA Belém PA Belém/PA topic practice 1

Resumen Esta investigación analizó el conocimiento de profesores y estudiantes de medicina sobre las directivas anticipadas, cuyo objetivo es garantizar los derechos de los pacientes a expresar su preferencia por la atención médica cuando ya no son capaces de comunicarse. Se trata de un estudio transversal, descriptivo, observacional, con enfoque mayoritariamente cuantitativo, en el que participaron 30 profesores de medicina y 121 estudiantes de medicina de dos instituciones de enseñanza situadas en Belém/PA. Los resultados revelaron vacíos en el conocimiento sobre el tema, lo que demuestra la necesidad de un abordaje en profundidad durante la formación y la práctica médica. Se concluye que hay una necesidad de intensificar el conocimiento de las voluntades anticipadas en la formación médica para favorecer la autonomía y la toma de decisiones compartida. comunicarse transversal descriptivo observacional cuantitativo 3 12 BelémPA Belém PA Belém/PA tema compartida 1

https://doi.org/10.1590/1983-803420243696pt

Human papillomavirus in women infected with human immunodeficiency virus: association with viral load and lymphocyte count virus
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Morais, Ana Cléa Cutrim Diniz de

; Ferreira, Alice de Sá

; Barbosa, Carla Déa Trindade

; Lima, Maria Fernanda Bezerra

; Fook, Karina Donato

; Carvalho, Mônika Machado de

; Muniz, Alessandra Costa de Sales

; Araújo, Deborah Rocha de

; Monteiro, Pablo de Matos

; Araújo, Maria José Abigail Mendes

; Monteiro, Sally Cristina Moutinho

; Lopes, Fernanda Ferreira

Revista do Instituto de Medicina Tropical de São Paulo

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2024, Volume 66 elocation e36

Abstract: En | Text: En | PDF: En

ABSTRACT Women living with human immunodeficiency virus are at an increased risk of developing cancers related to human papillomavirus (HPV). Thus, it is important to combine clinical assessments, serological screening, and HPV data for planning prevention policies. This study aimed to identify HPV and its specific types in the cervical, anal, and oral mucosa of HIV-seropositive women, associating it with viral load and lymphocyte count. Sociodemographic characteristics, health data (CD4+ and CD8+ T cell counts and viral load), and biological samples (cervical, anal, and oral) were collected from 86 HIV-positive women undergoing antiretroviral therapy. Data were classified according to the presence or absence of HPV-DNA, HPV-DNA presence at one or more anatomic sites, and level of oncogenic risk, considering low- and high-risk oncogenic HPV-DNA groups. The presence of HPV in the cervicovaginal site was 65.9%, 63.8% in anal canal, and 4.2% in oral mucosa. A viral load ≥75 HIV copies/mL was associated with the presence of HPV-DNA. There was an association between viral load and the low-risk HPV or high-risk HPV groups. We found a high prevalence of HPV infection in HIV-seropositive women, particularly in the cervical and anal mucosa, with viral load ≥75 HIV copies/mL being associated with HPV-DNA presence. HPV. . (HPV) Thus assessments screening policies HIVseropositive seropositive count characteristics CD4+ CD4 CD (CD4 CD8 load, , load) (cervical 8 HIVpositive positive therapy HPVDNA, HPVDNA DNA, DNA sites low highrisk groups 659 65 9 65.9% 638 63 63.8 canal 42 4 2 4.2 75 ≥7 copiesmL copies mL HPVDNA. DNA. lowrisk (HPV (CD 6 65.9 63. 4. 7 ≥ 65.

https://doi.org/10.1590/s1678-9946202466036

Translation and cultural adaptation of the Positive Aspects of Caregiving Scale for caregivers of people living with dementia in Brazilian context: a methodological study context
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Pavarini, Sofia Cristina Iost

; Gratão, Aline Cristina Martins

; Campos, Camila Rafael Ferreira

; Monteiro, Diana Quirino

; Barham, Elizabeth Joan

; Orlandi, Fabiana de Souza

; Martins, Gabriela

; Barbosa, Gustavo Carrijo

; Cruz, Keila Cristianne Trindade da

; Corrêa, Larissa

; Rocha, Luana Aparecida da

; Alves, Ludmyla Caroline de Souza

; Ottaviani, Ana Carolina

Sao Paulo Medical Journal

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2024, Volume 142 N. 2 elocation e2023325

Abstract: En | Text: En | PDF: En

ABSTRACT BACKGROUND: The Positive Aspects of Caregiving (PAC) scale is used to assess psychosocial benefits provided to caregivers by the task of caring. The PAC scale consists of nine items, assessed using a five-point Likert scale, with higher values indicating greater positive perceptions and gains from the caregiving experience. OBJECTIVE: To translate and culturally adapt the PAC scale for informal Brazilian caregivers of people with dementia. DESIGN AND SETTING: A methodological study was conducted at the Federal University of São Carlos. METHODS: The following stages were carried out: Translation; Synthesis of the translations; Back-translation; Evaluation by an experts’ committee; and Pre-test. RESULTS: Two independent professionals translated the PAC scale. The consensus version was obtained by merging both translations, which were back-translated into English by a third translator. The expert committee comprised three specialists in the area and project researchers. All scale items presented a Content Validity Index of 1 (CVI = 1.0), and thus remained in the pre-final version of the instrument. The instrument was pre-tested with seven caregivers of people with dementia, the majority of whom were women (57.1%), with a degree of kinship corresponding to sons/daughters (57.1%) and an average age of 55.2 (± 4.1) years. The caregivers considered it clear and understandable and made no suggestions for changes. CONCLUSION: The PAC scale was translated and culturally adapted for use by informal caregivers of people with dementia in Brazil. However, a psychometric analysis of the instrument is necessary to provide normative data for this population group. BACKGROUND (PAC caring fivepoint five point experience OBJECTIVE SETTING Carlos METHODS out Translation translations Backtranslation Back translation Back-translation experts Pretest. Pretest Pre test. test Pre-test RESULTS backtranslated back translator researchers CVI 1.0, 10 1.0 , 0 1.0) prefinal pre final pretested tested 57.1%, 571 57.1% 57 sonsdaughters sons daughters (57.1% 552 55 2 55. ± ( 4.1 41 4 years changes CONCLUSION Brazil However group 1. 57.1 5 (57.1 4. 57. (57. (57 (5

https://doi.org/10.1590/1516-3180.2023.0325.r1.23012024

10.

Sense of mastery in caregivers of people living with dementia: translation and cultural adaptation of the Pearlin Mastery Scale dementia
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Barbosa, Gustavo Carrijo

; Ottaviani, Ana Carolina

; Monteiro, Diana Quirino

; Campos, Camila Rafael Ferreira

; Cruz, Keila Cristianne Trindade da

; Alves, Ludmyla Caroline de Souza

; Corrêa, Larissa

; Rocha, Luana Aparecida

; Martins, Gabriela

; Melo, Beatriz Rodrigues de Souza

; Barham, Elizabeth Joan

; Pavarini, Sofia Cristina Iost

; Orlandi, Fabiana de Souza

; Gratão, Aline Cristina Martins

Dementia & Neuropsychologia

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2024, Volume 18 elocation e20230086

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O senso de domínio é conceituado como um aspecto positivo do cuidado voltado às pessoas que vivem com demência, um mecanismo de enfrentamento para reduzir a sobrecarga e que pode representar um fator protetor para a saúde mental e física do cuidador. Objetivo: Traduzir e adaptar culturalmente a Pearlin Mastery Scale para o Brasil. Métodos: Estudo metodológico conduzido na Universidade Federal de São Carlos, em que foram seguidas as etapas de tradução inicial; síntese; retrotradução; revisão pelo comitê de juízes pela análise do Índice de Validade de Conteúdo (IVC); e teste da versão pré-final. Resultados: Dois especialistas traduziram a escala para o português brasileiro e definiram uma versão consensual com os pesquisadores. Posteriormente, outros dois especialistas retrotraduziram a versão consensual, que foi revisada por três juízes doutores na área, considerando todos os itens da escala como muito equivalentes (IVC=1,0), mantendo-os na versão pré-final do instrumento. Esta foi testada em um primeiro grupo de cuidadores, a fim de se apontarem adequações. As sugestões foram acatadas mediante a modificação de três itens e, depois, a escala foi testada em um segundo grupo, o qual não apresentou dificuldades em responder ao instrumento. Conclusão: A Pearlin Mastery Scale foi traduzida e adaptada culturalmente para o Brasil, demonstrando equivalência. Entretanto, análises psicométricas futuras do instrumento são necessárias para disponibilizá-lo para uso entre essa população. demência cuidador Objetivo Brasil Métodos Carlos inicial síntese retrotradução IVC (IVC) préfinal. préfinal pré final. final Resultados pesquisadores Posteriormente área IVC=1,0, IVC10 IVC=1,0 , 1 0 (IVC=1,0) mantendoos mantendo cuidadores adequações depois Conclusão equivalência Entretanto disponibilizálo disponibilizá lo população (IVC IVC1 IVC=1, (IVC=1,0 IVC=1 (IVC=1, IVC= (IVC=1 (IVC=

ABSTRACT The sense of mastery is conceptualized as a positive aspect of care targeted at people living with dementia, a coping mechanism to reduce burden, and may represent a protective factor for caregivers’ mental and physical health. Objective: To translate and culturally adapt the Pearlin Mastery Scale for Brazil. Methods: A methodological study was conducted at the Federal University of São Carlos in which the initial translation stages were followed; synthesis; back-translation; review by the committee of judges by analyzing the Content Validity Index (CVI); and test of the pre-final version. Results: Two specialists translated the scale into Brazilian Portuguese and defined a consensus version with the researchers. Subsequently, another two specialists back-translated the consensus version, which was reviewed by three judges who are PhDs in the area, considering all scale items as very equivalent (CVI=1.0), and maintaining them in the pre-final version of the instrument. This was tested in a first group of caregivers for them to point out adjustments. The suggestions were accepted by modifying three items and, afterward, the scale was tested in a second group, which did not present difficulties answering the instrument. Conclusion: The Pearlin Mastery Scale was translated and culturally adapted for Brazil, showing equivalence. However, future psychometric analyses of the instrument are required to make it available for use in this population. dementia burden health Objective Brazil Methods followed synthesis backtranslation back back-translation CVI (CVI) prefinal pre final Results researchers Subsequently backtranslated area CVI=1.0, CVI10 CVI=1.0 , 1 0 (CVI=1.0) adjustments afterward Conclusion equivalence However population (CVI CVI1 CVI=1. (CVI=1.0 CVI=1 (CVI=1. CVI= (CVI=1 (CVI=

https://doi.org/10.1590/1980-5764-dn-2023-0086

11.

Lesão renal aguda em pacientes adultos com COVID-19: revisão integrativa COVID19 COVID 19 COVID-19 COVID1 1 COVID-1 COVID-
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Pereira, Ana Clara Alcântara Mendes

; Almeida, Jéssica Cristina

; Aguiar, Beatriz Regina Lima de

; Ferreira, Elaine Barros

; Rocha, Priscilla Roberta Silva

Acta Paulista de Enfermagem

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2024, Volume 37 elocation eAPE02532

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo Objetivo Identificar a frequência de lesão renal aguda (LRA) em pacientes hospitalizados com COVID-19, as características associadas, a mortalidade e a letalidade. Métodos Revisão realizada nas bases de dados CINAHL, Embase, LILACS, Livivo, PubMed, SCOPUS, Web of Science e, na literatura cinzenta (Google Acadêmico) em 12 de janeiro de 2022. Foram incluídos artigos em inglês, espanhol e português, publicados a partir de novembro 2019 até janeiro de 2022, em pacientes maiores de 18 anos com COVID-19 hospitalizados e LRA conforme critério Kidney Disease Improving Global Outcomes (KDIGO). Os estudos selecionados foram lidos na íntegra para extração, interpretação, síntese e categorização conforme nível de evidência. Resultados 699 artigos encontrados e 45 incluídos. A idade avançada, sexo masculino, hipertensão, doença renal crônica, ventilação mecânica, aumento da proteína C reativa, uso de drogas vasoativas e de determinadas classes de anti-hipertensivos foram associados a LRA. A LRA está relacionada à maior frequência de mortalidade. Em 30% dos pacientes hospitalizados com COVID-19 houve LRA. A taxa de mortalidade por LRA foi de 5% e a letalidade de 18%. Conclusão Estes resultados ressaltam a relevância da LRA como uma complicação significativa da COVID-19 e sugerem que um controle mais cuidadoso e precoce dos fatores associados poderia potencialmente reduzir a mortalidade e a letalidade. É crucial intensificar a pesquisa nesse campo para esclarecer melhor os mecanismos envolvidos na lesão renal em pacientes com COVID-19, bem como identificar estratégias terapêuticas mais efetivas para sua prevenção e tratamento nesse contexto. (LRA COVID19, COVID19 COVID 19, 19 associadas CINAHL Embase LILACS Livivo PubMed SCOPUS Google Acadêmico 1 2022 inglês português 201 COVID-1 KDIGO. KDIGO . (KDIGO) extração interpretação evidência 69 4 avançada masculino hipertensão crônica mecânica reativa antihipertensivos anti hipertensivos 30 5 18% contexto COVID1 202 20 COVID- (KDIGO 6 3 2

Abstract Objective To identify the frequency of acute kidney injury (AKI) in patients hospitalized with COVID-19, associated characteristics, mortality and lethality. Methods Integrative review carried out in the databases CINAHL, Embase, LILACS, Livivo, PubMed, SCOPUS, Web of Science and in the grey literature (Google Scholar) on January 12, 2022. Articles were included in English, Spanish and Portuguese, published from November 2019 to January 2022, in hospitalized patients over 18 years old with COVID-19 and AKI according to the Kidney Disease Improving Global Outcomes (KDIGO) criteria. The selected studies were read in full for extraction, interpretation, synthesis and categorization according to the level of evidence. Results A total of 699 articles were found and 45 included. Older age, male gender, hypertension, chronic kidney disease, mechanical ventilation, increased C-reactive protein, use of vasoactive drugs and certain classes of antihypertensives were associated with AKI. AKI is related to a higher frequency of mortality. AKI occurred in 30% of patients hospitalized with COVID-19. The mortality rate from AKI was 5% and the case fatality rate was 18%. Conclusion These results highlight the relevance of AKI as a significant complication of COVID-19 and suggest that more careful and early control of associated factors could potentially reduce mortality and lethality. It is crucial to intensify research in this field to better clarify the mechanisms involved in kidney injury in COVID-19 patients, as well as to identify more effective therapeutic strategies for its prevention and treatment in this context. (AKI COVID19, COVID19 COVID 19, 19 characteristics lethality CINAHL Embase LILACS Livivo PubMed SCOPUS Google Scholar 12 2022 English Portuguese 201 1 COVID-1 KDIGO (KDIGO criteria extraction interpretation evidence 69 4 age gender hypertension disease ventilation Creactive C reactive protein 30 COVID19. 19. 5 18% context COVID1 202 20 COVID- 6 3 2

Resumen Objetivo Identificar la frecuencia de lesión renal aguda (LRA) en pacientes hospitalizados con COVID-19, las características relacionadas, la mortalidad y la letalidad. Métodos Revisión realizada en las bases de datos CINAHL, Embase, LILACS, Livivo, PubMed, SCOPUS, Web of Science y en la literatura gris (Google Académico) el 12 de enero de 2022. Se incluyeron artículos en inglés, español y portugués, publicados a partir de noviembre de 2019 hasta enero de 2022, con pacientes mayores de 18 años con COVID-19 hospitalizados y LRA de acuerdo con el criterio Kidney Disease Improving Global Outcomes (KDIGO). Los estudios seleccionados fueron leídos en su totalidad para extracción, interpretación, síntesis y categorización según el nivel de evidencia. Resultados Se encontraron 699 artículos y se incluyeron 45. Los factores relacionados con la LRA fueron: edad avanzada, sexo masculino, hipertensión, enfermedad renal crónica, ventilación mecánica, aumento de la proteína C reactiva, uso de drogas vasoactivas y de determinadas clases de antihipertensivos. La LRA está relacionada con mayor frecuencia de mortalidad. En el 30 % de los pacientes hospitalizados con COVID-19 hubo LRA. La tasa de mortalidad por LRA fue de 5 % y la letalidad de 18 %. Conclusión Estos resultados resaltan la relevancia de la LRA como una complicación significativa de COVID-19 y sugieren que un control más cuidadoso y temprano de los factores asociados podría reducir potencialmente la mortalidad y la letalidad. Es crucial intensificar la investigación en este campo para explicar mejor los mecanismos relacionados con la lesión renal en pacientes con COVID-19, así como identificar estrategias terapéuticas más efectivas para su prevención y tratamiento en este contexto. (LRA COVID19, COVID19 COVID 19, 19 relacionadas CINAHL Embase LILACS Livivo PubMed SCOPUS Google Académico 1 2022 inglés portugués 201 COVID-1 KDIGO. KDIGO . (KDIGO) extracción interpretación evidencia 69 45 avanzada masculino hipertensión crónica mecánica reactiva antihipertensivos 3 contexto COVID1 202 20 COVID- (KDIGO 6 4 2

https://doi.org/10.37689/acta-ape/2024ar002532

12.

Recommendations on cutaneous and hematological manifestations of Sjögren’s disease by the Brazilian Society of Rheumatology Sjögrens Sjögren s
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Pugliesi, Alisson

; Egypto, Danielle Christinne Soares do

; Duffles, Guilherme

; Cantali, Diego Ustárroz

; Pasoto, Sandra Gofinet

; Oliveira, Fabiola Reis

; Valim, Valeria

; Lopes, Maria Lucia Lemos

; Miyamoto, Samira Tatiyama

; Fernandes, Marilena Leal Mesquita Silvestre

; Fialho, Sonia Cristina de Magalhães Souza

; Pinheiro, Aysa César

; Santos, Laura Caldas dos

; Appenzeller, Simone

; Ribeiro, Sandra Lucia Euzébio

; Libório-Kimura, Tatiana Nayara

; Santos, Maria Carmen Lopes Ferreira Silva

; Gennari, Juliana D´Agostino

; Pernanbuco, Roberta

; Capobiano, Karina Gatz

; Civile, Vinicius Tassoni

; Pinto, Ana Carolina Pereira Nunes

; Rocha-Filho, César Ramos

; Rocha, Aline Pereira da

; Trevisani, Virginia Fernandes Moça

Advances in Rheumatology

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2024, Volume 64 elocation 51

Abstract: En | Text: En | PDF: En

Abstract Sjogren’s disease (SjD) is an autoimmune disease that is characterized not only by the sicca symptoms it causes but also by its systemic nature, which is capable of several and not yet fully understood extraglandular manifestations. To gain a clearer understanding of these manifestations as well as a better practical approach, a panel of experts from the Brazilian Society of Rheumatology conducted a systematic review and meta-analysis on the identification of epidemiologic and clinical features of the extraglandular manifestations present in ESSDAI (EULAR Sjogren´s syndrome disease activity index), followed by a voting panel with recommendations for clinical practice. This publication is complementary to others already published and covers cutaneous and hematological manifestations, with prevalence data generated by a meta-analysis of 13 clinical or laboratory manifestations and 6 clinical management recommendations. Sjogrens Sjogren s SjD (SjD nature approach metaanalysis meta analysis EULAR index, index , index) practice 1

https://doi.org/10.1186/s42358-024-00391-x

13.

Diretriz sobre Diagnóstico e Tratamento da Cardiomiopatia Hipertrófica – 2024 202 20 2
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Fernandes, Fabio

; Simões, Marcus V.

; Correia, Edileide de Barros

; Marcondes-Braga, Fabiana Goulart

; Coelho-Filho, Otavio Rizzi

; Mesquita, Cláudio Tinoco

; Mathias Junior, Wilson

; Antunes, Murillo de Oliveira

; Arteaga-Fernández, Edmundo

; Rochitte, Carlos Eduardo

; Ramires, Felix José Alvarez

; Alves, Silvia Marinho Martins

; Montera, Marcelo Westerlund

; Lopes, Renato Delascio

; Oliveira Junior, Mucio Tavares de

; Scolari, Fernando Luis

; Avila, Walkiria Samuel

; Canesin, Manoel Fernandes

; Bocchi, Edimar Alcides

; Bacal, Fernando

; Moura, Lidia Zytynski

; Saad, Eduardo Benchimol

; Scanavacca, Mauricio Ibrahim

; Valdigem, Bruno Pereira

; Cano, Manuel Nicolas

; Abizaid, Alexandre Antonio Cunha

; Ribeiro, Henrique Barbosa

; Lemos Neto, Pedro Alves

; Ribeiro, Gustavo Calado de Aguiar

; Jatene, Fabio Biscegli

; Dias, Ricardo Ribeiro

; Beck-da-Silva, Luis

; Rohde, Luis Eduardo Paim

; Bittencourt, Marcelo Imbroinise

; Pereira, Alexandre da Costa

; Krieger, José Eduardo

; Villacorta Junior, Humberto

; Martins, Wolney de Andrade

; Figueiredo Neto, José Albuquerque de

; Cardoso, Juliano Novaes

; Pastore, Carlos Alberto

; Jatene, Ieda Biscegli

; Tanaka, Ana Cristina Sayuri

; Hotta, Viviane Tiemi

; Romano, Minna Moreira Dias

; Albuquerque, Denilson Campos de

; Mourilhe-Rocha, Ricardo

; Hajjar, Ludhmila Abrahão

; Brito Junior, Fabio Sandoli de

; Caramelli, Bruno

; Calderaro, Daniela

; Farsky, Pedro Silvio

; Colafranceschi, Alexandre Siciliano

; Pinto, Ibraim Masciarelli Francisco

; Vieira, Marcelo Luiz Campos

; Danzmann, Luiz Claudio

; Barberato, Silvio Henrique

; Mady, Charles

; Martinelli Filho, Martino

; Torbey, Ana Flavia Malheiros

; Schwartzmann, Pedro Vellosa

; Macedo, Ariane Vieira Scarlatelli

; Ferreira, Silvia Moreira Ayub

; Schmidt, Andre

; Melo, Marcelo Dantas Tavares de

; Lima Filho, Moysés Oliveira

; Sposito, Andrei C.

; Brito, Flávio de Souza

; Biolo, Andreia

; Madrini Junior, Vagner

; Rizk, Stephanie Itala

; Mesquita, Evandro Tinoco

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 7 elocation e202400415

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.36660/abc.20240415

14.

Hearing Performance in Cochlear Implant Users Who Have Facial Nerve Stimulation
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Rocha, Larissa Veloso

; Goffi-Gomez, Maria Valéria Schmidt

; Hoshino, Ana Cristina

; Tsuji, Robinson Koji

; Bento, Ricardo Ferreira

International Archives of Otorhinolaryngology

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2024, Volume 28 N. 2 Pages 301 - 306

Abstract: En | Text: En | PDF: En

Abstract Introduction Facial nerve stimulation (FNS) is a complication in cochlear implant (CI) when the electrical current escapes from the cochlea to the nearby facial nerve. Different management to reduce its effects are available, although changes might result in a less-than-ideal fitting for the CI user, eventually reducing speech perception. Objective To verify the etiologies that cause FNS, to identify strategies in managing FNS, and to evaluate speech recognition in patients who present FNS. Methods Retrospective study approved by the Ethical Board of the Institution. From the files of a CI group, patients who were identified with FNS either during surgery or at any time postoperatively were selected. Data collection included: CI manufacturer, electrode array type, age at implantation, etiology of hearing loss, FNS identification date, number of electrodes that generated FNS, FNS management actions, and speech recognition in quiet and in noise. Results Data were collected from 7 children and 25 adults. Etiologies that cause FNS were cochlear malformation, head trauma, meningitis, and otosclerosis; the main actions included decrease in the stimulation levels followed by the deactivation of electrodes. Average speech recognition in quiet before FNS was 86% and 80% after in patients who were able to accomplish the test. However, there was great variability, ranging from 0% in quiet to 90% of speech recognition in noise. Conclusion Etiologies that cause FNS are related to cochlear morphology alterations. Facial nerve stimulation can be solved using speech processor programming parameters; however, it is not possible to predict outcomes, since results depend on other variables. (FNS (CI available lessthanideal less than ideal user perception Institution group selected manufacturer type implantation loss date noise 2 adults malformation trauma meningitis otosclerosis 86 80 test However variability 0 90 alterations parameters however outcomes variables 8 9

https://doi.org/10.1055/s-0043-1775809

15.

How can we reduce maternal mortality due to preeclampsia? The 4P rule preeclampsia P
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Korkes, Henri Augusto

; Cavalli, Ricardo Carvalho

; Oliveira, Leandro Gustavo De

; Ramos, José Geraldo Lopes

; Martins Costa, Sérgio Hofmeister de Almeida

; Sousa, Francisco Lázaro Pereira de

; Vieira da Cunha Filho, Edson

; de Souza Mesquita, Maria Rita

; Dias Corrêa Júnior, Mário

; Pinheiro Fernandes Araújo, Ana Cristina

; Zaconeta, Alberto Carlos Moreno

; Freire, Carlos Henrique Esteves

; Poli de Figueiredo, Carlos Eduardo

; Rocha Filho, Edilberto Alves Pereira da

; Sass, Nelson

; Peraçoli, José Carlos

; Costa, Maria Laura

Revista Brasileira de Ginecologia e Obstetrícia

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2024, Volume 46 elocation e-rbgo43

Abstract: En | Text: En | PDF: En

Abstract In low and middle-income countries such as Brazil, most maternal deaths are related to hypertensive complications. Preeclampsia is the leading cause of maternal mortality and morbidity. Significant proportion is associated with the following factors: lack of identification of high-risk women, lack of adequate prevention, difficulty in maintaining a high-risk prenatal follow-up, delayed diagnosis, insecurity and low use of magnesium sulphate, delayed pregnancy interruption and lack of postpartum follow-up of these high-risk cases. Four major actions are proposed to minimize this alarming clinical picture and reduce the mortality rates due to preeclampsia, called the "4 P Rule" (Adequate Prevention – Vigilant Prenatal Care – Timely Delivery (Parturition) – Safe Postpartum). From this simple "rule" we can open a range of important processes and reminders that may help in the guidance of preeclampsia management. middleincome middle income Brazil complications morbidity factors highrisk high risk women prevention followup, followup follow up, up diagnosis sulphate cases 4 " Rule Adequate Parturition (Parturition Postpartum. Postpartum . Postpartum) rule "rule management

https://doi.org/10.61622/rbgo/2024rbgo43

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