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ABSTRACT Objective: The latest edition of the Open Drug Scenes Survey in Brazilian Cities (LECUCA) investigated social vulnerability, health, and the use of the Psychosocial Care Network by attendees of open drug scenes (ODSs) involving crack cocaine in São Paulo, Fortaleza, and Brasília between 2021/2022. Methods: Since 2016, LECUCA has used Time-Location Sampling (TLS) to select probabilistic samples representative of the population of ODS attendees. Results: We interviewed 579 participants in São Paulo, Fortaleza, and Brasília, obtaining a response rate of 75%. We found no difference in ODS attendees regarding the prevalence of sociodemographic indicators and time living in the ODS. The prevalence values of attendees who had never been homeless before living in the ODS and those living in their homes were equally high in the three capitals. Fortaleza stood out for having lower rates of homelessness and limited access to specialized health services, whereas Brasília had high rates of searching for emergency services due to drug use and greater access to all modalities of health and assistance services. Unprotected sex was prevalent over one third of ODSs attendees, and none of the capitals had more than half of the attendees testing for tuberculosis and sexually transmitted infections. Rates of pregnancy complications were high in all three capitals, with São Paulo accounting for the lowest rates. Conclusion: LECUCA provides significant subsidies to governmental and institutional managers, aiming at catalyzing the formulation of public policies and care strategies based on data and evidence.

RESUMO Objetivo: A última edição do Levantamento de Cenas de Uso de Capitais (LECUCA) investigou indicadores de vulnerabilidade social, de saúde e uso de serviços de saúde e assistência entre frequentadores das cenas abertas de uso (CAU) de crack em São Paulo, Fortaleza e Brasília entre 2021/2022. Métodos: Desde 2016, o LECUCA utiliza a amostragem por Tempo-Localização (TLS) para selecionar amostras probabilísticas representativas da população de frequentadores da CAU. Resultados: Foram entrevistados 579 participantes em São Paulo, Fortaleza e Brasília, com índice de resposta de 75%. Os frequentadores das CAUs não se diferenciam nas prevalências de indicadores sociodemográficos e tempo na cena. As prevalências de frequentadores que nunca estiveram em situação de rua antes de viver na CAU e provenientes de casa foram igualmente altas nas três capitais. Fortaleza se destaca com menores índices de situação de rua e de acesso a equipamentos de saúde especializados, enquanto Brasília apresenta índices elevados de busca por emergência devido ao consumo de drogas e maior acesso a todas as modalidades de serviço de saúde e assistência. Mais de um terço dos frequentadores das CAUs pratica sexo desprotegido e nenhuma das capitais teve mais da metade dos frequentadores testados para Tuberculose e Infecções Sexualmente Transmissíveis (ISTs). Os índices de problemas na gestação foram altos entre todas as capitais, com os menores índices em São Paulo. Conclusão: O LECUCA oferece subsídios importantes para gestores governamentais e institucionais, com o intuito de catalisar o desenvolvimento de políticas públicas e estratégias de atendimento fundamentadas em dados e evidências.

https://doi.org/10.1590/1980-549720250008

Association of sociodemographic and clinical factors with the quality of life of Brazilian individuals with Neurofibromatosis type 1: a cross-sectional study 1 crosssectional cross sectional
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Bicudo, Natália Parenti

; Germano, Carla Maria Ramos

; Moraes, Roberta Teixeira de

; Avó, Lucimar Retto da Silva de

; Ferner, Rosalie E.

; Melo, Débora Gusmão

Anais Brasileiros de Dermatologia

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aug 2024, Volume 99 N. 4 Pages 520 - 526

Abstract: En | Text: En | PDF: En

Abstract Background Neurofibromatosis type 1 (NF1) is a rare genetic disorder with a wide range of clinical manifestations, notably neurocutaneous features, that can lead to emotional and physical consequences. Objectives This study assessed the influence of sociodemographic factors and clinical features of the disease on the quality of life of Brazilian individuals with NF1. Methods This is a descriptive cross-sectional study. Data were collected from 101 individuals with NF1 using the Brazilian version of the Impact of NF1 on Quality of Life Questionnaire (INF1-QoL), a form with information on sociodemographic characteristics, and an NF1 visibility self-evaluation scale. The relationship between variables was evaluated through statistical testing, and the significance level was defined as 0.05. Results The study included 101 adults with NF1 aged 18 to 59 years, with a mean age of 35.54 years (±9.63) and a female predominance (n = 84, 83.17%). The mean total INF1-QoL score was 10.62 (±5.63), with a median of 10, minimum value of 0, and maximum of 31 points. Two characteristics of the participants were significantly associated with the quality of life: educational level (p = 0.003) and familial history of NF1 (p = 0.019). There was a statistically significant correlation between the INF1-QoL score and the degree of disease visibility (rho = 0.218; p = 0.028). Study limitations Cross-sectional study, conducted with a convenience sample and using self-reported measures. Conclusions The findings support the significant impact of NF1 on quality of life. The authors recommend multidisciplinary follow-up for patients, with adherence to anticipatory clinical care measures, adequate pain control, psychological assistance, and genetic counseling. NF (NF1 manifestations consequences crosssectional cross sectional 10 INF1QoL, INF1QoL INFQoL INF1 QoL , INF (INF1-QoL) selfevaluation self evaluation scale testing 005 0 05 0.05 5 3554 35 54 35.5 ±9.63 963 9 63 (±9.63 n 84 83.17%. 8317 83.17% . 83 17 83.17%) 1062 62 10.6 ±5.63, 563 ±5.63 (±5.63) 3 points 0.003 0003 003 0.019. 0019 0.019 019 0.019) rho 0.218 0218 218 0.028. 0028 0.028 028 0.028) Crosssectional Cross selfreported reported measures followup follow up patients control assistance counseling (NF (INF1-QoL 00 0.0 355 35. ±9.6 96 6 (±9.6 8 831 83.17 106 10. 56 ±5.6 (±5.63 0.00 000 001 0.01 01 0.21 021 21 002 0.02 02 0. ±9. (±9. 83.1 ±5. (±5.6 0.2 2 ±9 (±9 83. ±5 (±5. ± (± (±5 (

https://doi.org/10.1016/j.abd.2023.08.011

EXPERIÊNCIAS QUE INFLUENCIAM NA SEXUALIDADE DE MULHERES QUE VIVENCIARAM VIOLÊNCIA CONJUGAL: GROUNDED THEORY
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Campos, Luana Moura

; Gomes, Nadirlene Pereira

; Almeida, Lilian Conceição Guimarães de

; Webler, Natália

; Virgens, Ionara da Rocha

; Assunção, Alcilene Coutinho Ramos

; Santos, Josinete Gonçalves dos

; Costa, Dália Maria de Sousa Gonçalves da

Reme: Revista Mineira de Enfermagem

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2024, Volume 28 elocation e-1532

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: compreender como as situações vivenciadas ao longo da vida influenciam na sexualidade de mulheres com história de violência conjugal. Método: trata-se de uma pesquisa qualitativa, baseada na Grounded Theory, em sua vertente straussiana; e na teoria analítica de gênero e patriarcado proposta por Kate Millett. A coleta de dados aconteceu por meio de entrevistas entre dezembro de 2020 e julho de 2021. Para efeito deste estudo, foi estruturado um primeiro grupo amostral, constituído por 17 mulheres assistidas pela Operação Especial Ronda Maria da Penha da Bahia, que direcionou para um segundo grupo amostral, representado por 10 profissionais de saúde da Estratégia de Saúde da Família. A partir da organização dos dados, foram construídas categorias atinentes ao componente Condições proposto pelo Modelo Paradigmático. Resultados: emergiram do presente estudo as seguintes categorias: (Não) aprendendo sobre a sexualidade; Acreditando ser responsabilidade da mulher satisfazer o homem sexualmente; e rememorando abuso sexual experienciado. Conclusão: O estudo sinaliza para a necessidade de apoio psicológico às mulheres com história de violência conjugal, com o propósito de viabilizar ressignificações dos traumas outrora vividos. Além disso, sugere-se fomentar o diálogo entre as parcerias, a fim de favorecer experiências positivas no âmbito da sexualidade. Urge ainda a inclusão da temática sexualidade em espaços educativos e serviços de saúde.

ABSTRACT Objective: to understand how situations experienced throughout life influence the sexuality of women with a history of marital violence. Method: this is a qualitative research, based on Grounded Theory, in its Straussian aspect; and in the analytical theory of gender and patriarchy proposed by Kate Millett. Data collection took place through interviews between December 2020 and July 2021. For this study, a first sample group was structured, consisting of 17 women assisted by the Special Operation Ronda Maria da Penha da Bahia (Operação Especial Ronda Maria da Penha), which was directed to a second sample group, represented by 10 health professionals from the Family Health Strategy. Based on the organization of the data, categories related to the Conditions component proposed by the Paradigmatic Model were constructed. Results: the following categories emerged from this study: (Not) learning about sexuality; Believing it is the woman's responsibility to satisfy the man sexually; and Remembering experienced sexual abuse. Conclusion: the study highlights the need for psychological support for women with a history of marital violence, to enable new meanings of the traumas previously experienced. Furthermore, it is suggested to encourage dialogue between partnerships, to encourage positive experiences in the field of sexuality. There is also an urgent need to include the topic of sexuality in educational spaces and health services.

RESUMEN Objetivo: Comprender cómo las situaciones vividas a lo largo de la vida influyen en la sexualidad de mujeres con historial de violencia conyugal. Método: se trata de una investigación cualitativa, basada en la Teoría Fundamentada en su vertiente straussiana; y en la teoría analítica de género y patriarcado propuesta por Kate Millett. La recolección de datos se realizó mediante entrevistas entre diciembre de 2020 y julio de 2021. Para este estudio, se estructuró un primer grupo muestral, compuesto por 17 mujeres asistidas por la Operación Especial Ronda Maria da Penha de Bahía, que derivó en un segundo grupo muestral, representado por 10 profesionales de la salud de la Estrategia de Salud de la Familia. A partir de la organización de los datos, se construyeron categorías pertinentes al componente Condiciones propuesto por el Modelo Paradigmático. Resultados: del presente estudio emergieron las siguientes categorías: (No) aprendiendo sobre la sexualidad; Creyendo que es responsabilidad de la mujer satisfacer sexualmente al hombre; y Rememorando el abuso sexual experimentado. Conclusión: el estudio señala la necesidad de apoyo psicológico para mujeres con historial de violencia conyugal, con el propósito de facilitar la resignificación de los traumas vividos anteriormente. Además, se sugiere fomentar el diálogo entre las parejas, con el fin de favorecer experiencias positivas en el ámbito de la sexualidad. Es urgente también la inclusión del tema de la sexualidad en espacios educativos y servicios de salud.

https://doi.org/10.35699/2316-9389.2023.41387

HIV and AIDS in the state of Paraná, Brazil, 2007-2022: trends and spatiotemporal distribution
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Montanha, Rafaela Marito

; Gioia, Thamy Barbara

; Ramos, Antônio Carlos Vieira

; Ferreira, Natalia Marciano de Araujo

; Torres, Miguel Angel Fuentealba

; Pimenta, Rosângela Aparecida

; Kerbauy, Gilselena

; Arcêncio, Ricardo Alexandre

; Pieri, Flávia Meneguetti

Revista Brasileira de Epidemiologia

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2024, Volume 27 elocation e240015

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Este estudo teve como objetivo analisar a evolução espaçotemporal das taxas de incidência do vírus da imunodeficiência humana (HIV) e da síndrome da imunodeficiência adquirida (AIDS) no estado do Paraná, Brasil. Métodos: Foi realizado um estudo ecológico com componente analítico de séries temporais e análise espacial no estado do Paraná, de 2007 a 2022. A fonte de dados foi o Sistema de Informação de Agravos de Notificação. Para estudar a tendência, foi utilizado o modelo de regressão linear generalizada de Prais-Winsten por meio da decomposição de séries temporais e, para a análise espacial, foi aplicado o Índice de Moran. Resultados: A amostra total foi composta de 50.676 registros de HIV/AIDS. A taxa de incidência apresentou tendência crescente, com crescimento médio de 2,14% (intervalo de confiança de 95% — IC95% 1,16–3,13) ao mês. Nos períodos de 2007 a 2014 e 2015 a 2022, a média de casos no estado foi de 105,64 e 159,20 a cada 100 mil habitantes, respectivamente, com importantes variações entre os municípios. Agrupamentos espaciais de alto risco permaneceram na região metropolitana à capital e litoral e um novo agrupamento foi observado à região norte do estado. Conclusão: As taxas de incidência do HIV/AIDS apresentaram tendência temporal crescente. O número de casos variou substancialmente em alguns municípios, principalmente naqueles localizados na região litorânea. A análise espacial revelou padrões geoespaciais de alto risco nas principais regiões metropolitanas do Paraná: Curitiba (abrange o litoral), Londrina e Maringá, as quais compartilham características como elevado grau de urbanização e constante desenvolvimento econômico.

ABSTRACT Objective: The aim of this study was to analyze the spatiotemporal evolution of the incidence rates of human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) in the state of Paraná, Brazil. Methods: An ecological study with an analytical component of time series analysis was conducted in the state of Paraná from 2007 to 2022. The data source was the Notifiable Diseases Information System. To study the trend, the Prais–Winsten generalized linear regression model was used by decomposing the time series, and for spatial analysis, the Moran's index was applied. Results: The total sample consisted of 50,676 HIV/AIDS records. The incidence rate showed an increasing trend, with an average growth of 2.14% [95% confidence interval – 95%CI 1.16–3.13] per month. From 2007 to 2014 and from 2015 to 2022, the average number of cases in the state was 105.64 and 159.20 per 100,000 inhabitants, respectively, with significant variation among municipalities. Spatial clusters of high risk persisted in the metropolitan region, the capital, and coastal areas, and a new cluster was observed in the northern region of the state. Conclusion: The incidence rates of HIV/AIDS showed an upward trend over time. The number of cases varied considerably in some municipalities, especially in the coastal region. Spatial analysis revealed geospatial patterns of high risk in the main metropolitan areas of Paraná: Curitiba (including the coastal area), Londrina, and Maringá, which share characteristics such as a high degree of urbanization and ongoing economic development.

https://doi.org/10.1590/1980-549720240015

Genetic Testing in Cardiomyopathy: Decoding Molecular Underpinnings and Influencing Treatment Decisions Cardiomyopathy
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Furquim, Silas Ramos

; Lipari, Layara Fernanda Vicente Pereira

; Andrade, Fernanda Almeida

; Correia, Vinícius Machado

; Olivetti, Natália Quintella Sangiorgi

; Pires, Lucas Vieira Lacerda

; Sacilotto, Luciana

; Fernandes, Fábio

; Krieger, José Eduardo

International Journal of Cardiovascular Sciences

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2024, Volume 37 elocation e20230153

Abstract: En | Text: En | PDF: En

Abstract Cardiomyopathy is characterized by structural and functional abnormalities in the heart muscle that are not influenced by coronary disease, hypertension, valve disease, or congenital heart defects. Genetic testing, which helps diagnose the molecular bases of cardiomyopathy, can affect prognostication and clinical decisions. Recent guidelines advocate classifying cardiomyopathies based on phenotypic categories, which encompass a range of clinical presentations, underlying causes, and outcomes. Beyond deepening our grasp of the disease, genetic testing can distinguish between diseases with similar presentations, known as genocopies, which can profoundly influence treatment decisions. Genetic testing is also essential for reproductive counseling and risk evaluation among family members. Combined with advanced imaging techniques such as magnetic resonance imaging, genetic investigation offers a comprehensive understanding of the disease. Thus, as the nature of cardiomyopathies continues to be unraveled, cardiologists must stay updated on advances in genetic testing and their practical applications. disease hypertension defects cardiomyopathy decisions categories presentations causes outcomes genocopies members Thus unraveled applications

https://doi.org/10.36660/ijcs.20230153

Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.

; Valim, Michel P.

; Zaher, Hussam

; Rafael, José A.

; Forzza, Rafaela C.

; Percequillo, Alexandre R.

; Serejo, Cristiana S.

; Garraffoni, André R.S.

; Santos, Adalberto J. Slipinski, Adam Linzmeier, Adelita M. Calor, Adolfo R. Garda, Adrian A. Kury, Adriano B. Fernandes, Agatha C.S. Agudo-Padrón, Aisur I. Akama, Alberto Silva Neto, Alberto M. da Burbano, Alejandro L. Menezes, Aleksandra Pereira-Colavite, Alessandre Anichtchenko, Alexander Lees, Alexander C. Bezerra, Alexandra M.R. Domahovski, Alexandre C. Pimenta, Alexandre D. Aleixo, Alexandre L.P. Marceniuk, Alexandre P. Paula, Alexandre S. de Somavilla, Alexandre Specht, Alexandre Camargo, Alexssandro Newton, Alfred F. Silva, Aline A.S. da Santos, Aline B. dos Tassi, Aline D. Aragão, Allan C. Santos, Allan P.M. Migotto, Alvaro E. Mendes, Amanda C. Cunha, Amanda Chagas Júnior, Amazonas Sousa, Ana A.T. de Pavan, Ana C. Almeida, Ana C.S. Peronti, Ana L.B.G. Henriques-Oliveira, Ana L. Prudente, Ana L. Tourinho, Ana L. Pes, Ana M.O. Carmignotto, Ana P. Wengrat, Ana P.G. da Silva Dornellas, Ana P.S. Molin, Anamaria Dal Puker, Anderson Morandini, André C. Ferreira, André da S. Martins, André L. Esteves, André M. Fernandes, André S. Roza, André S. Köhler, Andreas Paladini, Andressa Andrade, Andrey J. de Pinto, Ângelo P. Salles, Anna C. de A. Gondim, Anne I. Amaral, Antonia C.Z. Rondón, Antonio A.A. Brescovit, Antonio Lofego, Antônio C. Marques, Antonio C. Macedo, Antonio Andriolo, Artur Henriques, Augusto L. Ferreira Júnior, Augusto L. Lima, Aurino F. de Barros, Ávyla R. de A. Brito, Ayrton do R. Romera, Bárbara L.V. Vasconcelos, Beatriz M.C. de Frable, Benjamin W. Santos, Bernardo F. Ferraz, Bernardo R. Rosa, Brunno B. Sampaio, Brunno H.L. Bellini, Bruno C. Clarkson, Bruno Oliveira, Bruno G. de Corrêa, Caio C.D. Martins, Caleb C. Castro-Guedes, Camila F. de Souto, Camilla Bicho, Carla de L. Cunha, Carlo M. Barboza, Carlos A. de M. Lucena, Carlos A.S. de Barreto, Carlos Santana, Carlos D.C.M. de Agne, Carlos E.Q. Mielke, Carlos G.C. Caetano, Carlos H.S. Flechtmann, Carlos H.W. Lamas, Carlos J.E. Rocha, Carlos Mascarenhas, Carolina S. Margaría, Cecilia B. Waichert, Cecilia Digiani, Celina Haddad, Célio F.B. Azevedo, Celso O. Benetti, Cesar J. Santos, Charles M.D. dos Bartlett, Charles R. Bonvicino, Cibele Ribeiro-Costa, Cibele S. Santos, Cinthya S.G. Justino, Cíntia E.L. Canedo, Clarissa Bonecker, Claudia C. Santos, Cláudia P. Carvalho, Claudio J.B. de Gonçalves, Clayton C. Galvão, Cleber Costa, Cleide Oliveira, Cléo D.C. de Schwertner, Cristiano F. Andrade, Cristiano L. Pereira, Cristiano M. Sampaio, Cristiano Dias, Cristina de O. Lucena, Daercio A. de A. Manfio, Daiara Amorim, Dalton de S. Queiroz, Dalva L. de Queiroz, Dalva L. de Colpani, Daniara Abbate, Daniel Aquino, Daniel A. Burckhardt, Daniel Cavallari, Daniel C. Prado, Daniel de C. Schelesky Praciano, Daniel L. Basílio, Daniel S. Bená, Daniela de C. Toledo, Daniela G.P. de Takiya, Daniela M. Fernandes, Daniell R.R. Ament, Danilo C. Cordeiro, Danilo P. Silva, Darliane E. Pollock, Darren A. Muniz, David B. Gibson, David I. Nogueira, David S. Marques, Dayse W.A. Lucatelli, Débora Garcia, Deivys M.A. Baêta, Délio Ferreira, Denise N.M. Rueda-Ramírez, Diana Fachin, Diego A. Souza, Diego de S. Rodrigues, Diego F. Pádua, Diego G. de Barbosa, Diego N. Dolibaina, Diego R. Amaral, Diogo C. Chandler, Donald S. Maccagnan, Douglas H.B. Caron, Edilson Carvalho, Edrielly Adriano, Edson A. Abreu Júnior, Edson F. de Pereira, Edson H.L. Viegas, Eduarda F.G. Carneiro, Eduardo Colley, Eduardo Eizirik, Eduardo Santos, Eduardo F. dos Shimbori, Eduardo M. Suárez-Morales, Eduardo Arruda, Eliane P. de Chiquito, Elisandra A. Lima, Élison F.B. Castro, Elizeu B. de Orlandin, Elton Nascimento, Elynton A. do Razzolini, Emanuel Gama, Emanuel R.R. Araujo, Enilma M. de Nishiyama, Eric Y. Spiessberger, Erich L. Santos, Érika C.L. dos Contreras, Eugenia F. Galati, Eunice A.B. Oliveira Junior, Evaldo C. de Gallardo, Fabiana Hernandes, Fabio A. Lansac-Tôha, Fábio A. Pitombo, Fabio B. Dario, Fabio Di Santos, Fábio L. dos Mauro, Fabio Nascimento, Fabio O. do Olmos, Fabio Amaral, Fabio R. Schunck, Fabio Godoi, Fábio S. P. de Machado, Fabrizio M. Barbo, Fausto E. Agrain, Federico A. Ribeiro, Felipe B. Moreira, Felipe F.F. Barbosa, Felipe F. Silva, Fenanda S. Cavalcanti, Fernanda F. Straube, Fernando C. Carbayo, Fernando Carvalho Filho, Fernando Zanella, Fernando C.V. Jacinavicius, Fernando de C. Farache, Fernando H.A. Leivas, Fernando Dias, Fernando M.S. Mantellato, Fernando Vaz-de-Mello, Fernando Z. Gudin, Filipe M. Albuquerque, Flávio Molina, Flavio B. Passos, Flávio D. Shockley, Floyd W. Pinheiro, Francielly F. Mello, Francisco de A.G. de Nascimento, Francisco E. de L. Franco, Francisco L. Oliveira, Francisco L. de Melo, Francisco T. de V. Quijano, Freddy R.B. Salles, Frederico F. Biffi, Gabriel Queiroz, Gabriel C. Bizarro, Gabriel L. Hrycyna, Gabriela Leviski, Gabriela Powell, Gareth S. Santos, Geane B. dos Morse, Geoffrey E. Brown, George Mattox, George M.T. Zimbrão, Geraldo Carvalho, Gervásio S. Miranda, Gil F.G. Moraes, Gilberto J. de Lourido, Gilcélia M. Neves, Gilmar P. Moreira, Gilson R.P. Montingelli, Giovanna G. Maurício, Giovanni N. Marconato, Gláucia Lopez, Guilherme E.L. Silva, Guilherme L. da Muricy, Guilherme Brito, Guilherme R.R. Garbino, Guilherme S.T. Flores, Gustavo E. Graciolli, Gustavo Libardi, Gustavo S. Proctor, Heather C. Gil-Santana, Helcio R. Varella, Henrique R. Escalona, Hermes E. Schmitz, Hermes J. Rodrigues, Higor D.D. Galvão Filho, Hilton de C. Quintino, Hingrid Y.S. Pinto, Hudson A. Rainho, Hugo L. Miyahira, Igor C. Gonçalves, Igor de S. Martins, Inês X. Cardoso, Irene A. Oliveira, Ismael B. de Franz, Ismael Fernandes, Itanna O. Golfetti, Ivan F. S. Campos-Filho, Ivanklin Oliveira, Ivo de S. Delabie, Jacques H.C. Oliveira, Jader de Prando, Jadila S. Patton, James L. Bitencourt, Jamille de A. Silva, Janaina M. Santos, Jandir C. Arruda, Janine O. Valderrama, Jefferson S. Dalapicolla, Jeronymo Oliveira, Jéssica P. Hájek, Jiri Morselli, João P. Narita, João P. Martin, João P.I. Grazia, Jocélia McHugh, Joe Cherem, Jorge J. Farias Júnior, José A.S. Fernandes, Jose A.M. Pacheco, José F. Birindelli, José L.O. Rezende, José M. Avendaño, Jose M. Duarte, José M. Barbanti Ribeiro, José R. Inácio Mermudes, José R.M. Pujol-Luz, José R. Santos, Josenilson R. dos Câmara, Josenir T. Teixeira, Joyce A. Prado, Joyce R. do Botero, Juan P. Almeida, Julia C. Kohler, Julia Gonçalves, Julia P. Beneti, Julia S. Donahue, Julian P. Alvim, Juliana Almeida, Juliana C. Segadilha, Juliana L. Wingert, Juliana M. Barbosa, Julianna F. Ferrer, Juliano Santos, Juliano F. dos Kuabara, Kamila M.D. Nascimento, Karine B. Schoeninger, Karine Campião, Karla M. Soares, Karla Zilch, Kássia Barão, Kim R. Teixeira, Larissa Sousa, Laura D. do N.M. de Dumas, Leandro L. Vieira, Leandro M. Azevedo, Leonardo H.G. Carvalho, Leonardo S. Souza, Leonardo S. de Rocha, Leonardo S.G. Bernardi, Leopoldo F.O. Vieira, Letícia M. Johann, Liana Salvatierra, Lidianne Oliveira, Livia de M. Loureiro, Lourdes M.A. El-moor Barreto, Luana B. Barros, Luana M. Lecci, Lucas Camargos, Lucas M. de Lima, Lucas R.C. Almeida, Lucia M. Martins, Luciana R. Marinoni, Luciane Moura, Luciano de A. Lima, Luciano Naka, Luciano N. Miranda, Lucília S. Salik, Lucy M. Bezerra, Luis E.A. Silveira, Luis F. Campos, Luiz A. Castro, Luiz A.S. de Pinho, Luiz C. Silveira, Luiz F.L. Iniesta, Luiz F.M. Tencatt, Luiz F.C. Simone, Luiz R.L. Malabarba, Luiz R. Cruz, Luiza S. da Sekerka, Lukas Barros, Lurdiana D. Santos, Luziany Q. Skoracki, Maciej Correia, Maira A. Uchoa, Manoel A. Andrade, Manuella F.G. Hermes, Marcel G. Miranda, Marcel S. Araújo, Marcel S. de Monné, Marcela L. Labruna, Marcelo B. Santis, Marcelo D. de Duarte, Marcelo Knoff, Marcelo Nogueira, Marcelo Britto, Marcelo R. de Melo, Marcelo R.S. de Carvalho, Marcelo R. de Tavares, Marcelo T. Kitahara, Marcelo V. Justo, Marcia C.N. Botelho, Marcia J.C. Couri, Márcia S. Borges-Martins, Márcio Felix, Márcio Oliveira, Marcio L. de Bologna, Marco A. Gottschalk, Marco S. Tavares, Marcos D.S. Lhano, Marcos G. Bevilaqua, Marcus Santos, Marcus T.T. Domingues, Marcus V. Sallum, Maria A.M. Digiani, María C. Santarém, Maria C.A. Nascimento, Maria C. do Becerril, María de los A.M. Santos, Maria E.A. dos Passos, Maria I. da S. dos Felippe-Bauer, Maria L. Cherman, Mariana A. Terossi, Mariana Bartz, Marie L.C. Barbosa, Marina F. de C. Loeb, Marina V. Cohn-Haft, Mario Cupello, Mario Martins, Marlúcia B. Christofersen, Martin L. Bento, Matheus Rocha, Matheus dos S. Martins, Maurício L. Segura, Melissa O. Cardenas, Melissa Q. Duarte, Mércia E. Ivie, Michael A. Mincarone, Michael M. Borges, Michela Monné, Miguel A. Casagrande, Mirna M. Fernandez, Monica A. Piovesan, Mônica Menezes, Naércio A. Benaim, Natalia P. Reategui, Natália S. Pedro, Natan C. Pecly, Nathalia H. Ferreira Júnior, Nelson Silva Júnior, Nelson J. da Perioto, Nelson W. Hamada, Neusa Degallier, Nicolas Chao, Ning L. Ferla, Noeli J. Mielke, Olaf H.H. Evangelista, Olivia Shibatta, Oscar A. Oliveira, Otto M.P. Albornoz, Pablo C.L. Dellapé, Pablo M. Gonçalves, Pablo R. Shimabukuro, Paloma H.F. Grossi, Paschoal Rodrigues, Patrícia E. da S. Lima, Patricia O.V. Velazco, Paul Santos, Paula B. dos Araújo, Paula B. Silva, Paula K.R. Riccardi, Paula R. Garcia, Paulo C. de A. Passos, Paulo G.H. Corgosinho, Paulo H.C. Lucinda, Paulo Costa, Paulo M.S. Alves, Paulo P. Roth, Paulo R. de O. Coelho, Paulo R.S. Duarte, Paulo R.M. Carvalho, Pedro F. de Gnaspini, Pedro Souza-Dias, Pedro G.B. Linardi, Pedro M. Bartholomay, Pedro R. Demite, Peterson R. Bulirsch, Petr Boll, Piter K. Pereira, Rachel M.M. Silva, Rafael A.P.F. Moura, Rafael B. de Boldrini, Rafael Silva, Rafaela A. da Falaschi, Rafaela L. Cordeiro, Ralf T.S. Mello, Ramon J.C.L. Singer, Randal A. Querino, Ranyse B. Heleodoro, Raphael A. Castilho, Raphael de C. Constantino, Reginaldo Guedes, Reinaldo C. Carrenho, Renan Gomes, Renata S. Gregorin, Renato Machado, Renato J.P. Bérnils, Renato S. Capellari, Renato S. Silva, Ricardo B. Kawada, Ricardo Dias, Ricardo M. Siewert, Ricardo Brugnera, Ricaro Leschen, Richard A.B. Constantin, Robert Robbins, Robert Pinto, Roberta R. Reis, Roberto E. dos Ramos, Robson T. da C. Cavichioli, Rodney R. Barros, Rodolfo C. de Caires, Rodrigo A. Salvador, Rodrigo B. Marques, Rodrigo C. Araújo, Rodrigo C. Araujo, Rodrigo de O. Dios, Rodrigo de V.P. Johnsson, Rodrigo Feitosa, Rodrigo M. Hutchings, Roger W. Lara, Rogéria I.R. Rossi, Rogério V. Gerstmeier, Roland Ochoa, Ronald Hutchings, Rosa S.G. Ale-Rocha, Rosaly Rocha, Rosana M. da Tidon, Rosana Brito, Rosangela Pellens, Roseli Santos, Sabrina R. dos Santos, Sandra D. dos Paiva, Sandra V. Santos, Sandro Oliveira, Sarah S. de Costa, Sávio C. Gardner, Scott L. Leal, Sebastián A. Muñoz Aloquio, Sergio Bonecker, Sergio L.C. Bueno, Sergio L. de S. Almeida, Sérgio M. de Stampar, Sérgio N. Andena, Sérgio R. Posso, Sergio R. Lima, Sheila P. Gadelha, Sian de S. Thiengo, Silvana C. Cohen, Simone C. Brandão, Simone N. Rosa, Simone P. Ribeiro, Síria L.B. Letana, Sócrates D. Santos, Sonia B. dos Andrade, Sonia C.S. Dávila, Stephane Vaz, Stéphanie Peck, Stewart B. Christo, Susete W. Cunha, Suzan B.Z. Gomes, Suzete R. Duarte, Tácio Madeira-Ott, Taís Marques, Taísa Roell, Talita Lima, Tarcilla C. de Sepulveda, Tatiana A. Maria, Tatiana F. Ruschel, Tatiana P. Rodrigues, Thaiana Marinho, Thais A. Almeida, Thaís M. de Miranda, Thaís P. Freitas, Thales R.O. Pereira, Thalles P.L. Zacca, Thamara Pacheco, Thaynara L. Martins, Thiago F. Alvarenga, Thiago M. Carvalho, Thiago R. de Polizei, Thiago T.S. McElrath, Thomas C. Henry, Thomas Pikart, Tiago G. Porto, Tiago J. Krolow, Tiago K. Carvalho, Tiago P. Lotufo, Tito M. da C. Caramaschi, Ulisses Pinheiro, Ulisses dos S. Pardiñas, Ulyses F.J. Maia, Valéria C. Tavares, Valeria Costa, Valmir A. Amaral, Vanessa S. do Silva, Vera C. Wolff, Vera R. dos S. Slobodian, Verônica Silva, Vinícius B. da Espíndola, Vinicius C. Costa-Silva, Vinicius da Bertaco, Vinicius de A. Padula, Vinícius Ferreira, Vinicius S. Silva, Vitor C.P. da Piacentini, Vítor de Q. Sandoval-Gómez, Vivian E. Trevine, Vivian Sousa, Viviane R. Sant’Anna, Vivianne B. de Mathis, Wayne N. Souza, Wesley de O. Colombo, Wesley D. Tomaszewska, Wioletta Wosiacki, Wolmar B. Ovando, Ximena M.C. Leite, Yuri L.R.

Zoologia (Curitiba)

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2024, Volume 41 elocation e24005

Abstract: En | Text: En | PDF: En

ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7

https://doi.org/10.1590/s1984-4689.v41.e24005

Natural language processing in at-risk mental states: enhancing the assessment of thought disorders and psychotic traits with semantic dynamics and graph theory atrisk at risk states
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Argolo, Felipe

; Ramos, William Henrique de Paula

; Mota, Natalia Bezerra Gondim, João Medrado Lopes-Rocha, Ana Caroline Andrade, Julio Cesar van de Bilt, Martinus Theodorus de Jesus, Leonardo Peroni Jafet, Andrea Cecchi, Guillermo Gattaz, Wagner Farid Corcoran, Cheryl Mary Ara, Anderson Loch, Alexandre Andrade

Brazilian Journal of Psychiatry

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2024, Volume 46 elocation e20233419

Abstract: En | Text: En | PDF: En

Objective: Verbal communication contains key information for mental health assessment. Researchers have linked psychopathology phenomena to certain counterparts in natural language processing. We characterized subtle impairments in the early stages of psychosis, developing new analysis techniques, which led to a comprehensive map associating features of natural language processing with the full range of clinical presentation. Methods: We used natural language processing to assess spontaneous and elicited speech by 60 individuals with at-risk mental states and 73 controls who were screened from 4,500 quota-sampled Portuguese speaking residents of São Paulo, Brazil. Psychotic symptoms were independently assessed with the Structured Interview for Psychosis-Risk Syndromes. Speech features (e.g., sentiments and semantic coherence), including novel ones, were correlated with psychotic traits (Spearman’s-ρ) and at-risk mental state status (general linear models and machine-learning ensembles). Results: Natural language processing features were informative for classification, presenting a balanced accuracy of 86%. Features such as semantic laminarity (as perseveration), semantic recurrence time (as circumstantiality), and average centrality in word repetition graphs carried the most information and were directly correlated with psychotic symptoms. Grammatical tagging (e.g., use of adjectives) was the most relevant standard measure. Conclusion: Subtle speech impairments can be detected by sensitive methods and can be used in at-risk mental states screening. We have outlined a blueprint for speech-based evaluation, pairing features to standard psychometric items for thought disorder. Objective assessment psychosis techniques presentation Methods 6 atrisk at risk 7 4500 4 500 4,50 quotasampled quota sampled Paulo Brazil PsychosisRisk Psychosis Risk Syndromes e.g., eg e g (e.g. coherence, coherence , coherence) ones Spearmansρ Spearman s ρ (Spearman’s-ρ general machinelearning machine learning ensembles. ensembles . ensembles) Results classification 86 86% perseveration, perseveration perseveration) circumstantiality, circumstantiality circumstantiality) adjectives measure Conclusion screening speechbased based evaluation disorder 450 50 4,5 e.g. (e.g 8 45 5 4, e.g

https://doi.org/10.47626/1516-4446-2023-3419

Inhibition of human tumor cell migration by a rice-derived chimeric cysteine protease inhibitor ricederived rice derived
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DIAS-OLIVEIRA, MATEUS

; BALBINOTT, NATALIA

; RAMOS, JÉSSICA M.O.

; VASCONCELLOS, JOÃO G.

; GUMA, FÁTIMA THERESINHA C.R.

; ZANATTA, GEANCARLO

; MARGIS, ROGERIO

Anais da Academia Brasileira de Ciências

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2024, Volume 96 Suppl. 3 elocation e20240778

Abstract: En | Text: En | PDF: En

Abstract The cystatin superfamily includes proteins crucial for inhibiting cysteine proteases, enzymes involved in many biological processes. In plants, cystatins regulate seed germination, development, and pathogen defense. In humans, inhibiting legumain-type cysteine proteases offers a promising cancer treatment strategy, as this enzyme’s expression often rises during tumor progression. We evaluated a novel rice-derived chimeric legumain inhibitor using in silico and in vitro methods. Computational simulations confirmed the inhibitor’s stability and nanomolar affinity for legumain’s active site. Post-expression and purification assays determined its kinetics and demonstrated its efficacy in reducing HT29 tumor cell migration and viability. Our findings suggest the chimeric Oryzacystatin I mutant with SNSL motifs is a promising candidate for cancer drug development. processes plants germination development defense humans legumaintype type strategy enzyme s progression ricederived rice derived methods inhibitors legumains site Postexpression Post HT HT2 viability

https://doi.org/10.1590/0001-3765202420240778

HIV and AIDS in the state of Paraná, Brazil, 2007-2022: trends and spatiotemporal distribution Paraná Brazil 20072022 2007 2022 2007-2022 2007202 200 202 2007-202 200720 20 2007-20 20072 2 2007-2 2007-
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Montanha, Rafaela Marito

; Gioia, Thamy Barbara

; Ramos, Antônio Carlos Vieira

; Ferreira, Natalia Marciano de Araujo

; Torres, Miguel Angel Fuentealba

; Pimenta, Rosângela Aparecida

; Kerbauy, Gilselena

; Arcêncio, Ricardo Alexandre

; Pieri, Flávia Meneguetti

Revista Brasileira de Epidemiologia

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2024, Volume 27 elocation e240015

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1980-549720240015

10.

Educational video for self-care with arteriovenous fistula in renal patients: randomized clinical trial selfcare self care patients
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Pessoa, Natália Ramos Costa

; Sales, Jackeline Kérollen Duarte de

; Sousa, Clemente Neves

; Lopes, Marcos Venícios de Oliveira

; Frazão, Cecília Maria Farias de Queiroz

; Ramos, Vânia Pinheiro

Revista Latino-Americana de Enfermagem

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2024, Volume 32 elocation e4185

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Objetivo: avaliar o efeito de um vídeo educacional no conhecimento, atitude e prática de autocuidado com a fístula arteriovenosa de pacientes em tratamento hemodialítico. Método: ensaio clínico randomizado controlado, com dois braços e unicego. A intervenção utilizou um vídeo educacional sobre o autocuidado com a fístula arteriovenosa. Foi aplicada a Escala de conhecimento, atitude e prática de autocuidado com a fístula em 27 pacientes renais em hemodiálise do grupo controle e 28 do grupo intervenção na linha de base, após sete e quatorze dias. Os dados foram analisados no software Statistical Package for the Social Sciences , com a aplicação dos testes qui-quadrado, T de Student, Mann-Whitney e Teste de Friedman com análise post-hoc para comparações múltiplas. Resultados: verificaram-se diferenças estatisticamente significantes no conhecimento e prática de autocuidado com a fístula no seguimento de 0, 7 e 14 dias dos grupos intervenção (p= 0,004 e p<0,001, respectivamente) e controle (p<0,001 para o conhecimento e prática). A atitude apresentou diferença significativa no seguimento (p<0,001), mas a análise post-hoc não confirmou a significância obtida. Conclusão: o conhecimento e prática dos pacientes apresentaram aumentos significativos no seguimento nos grupos controle e intervenção, enquanto o aumento da atitude não foi significativo em nenhum dos grupos. Ensaio clínico, número de registro: U1111-1241-6730. Objetivo hemodialítico Método controlado unicego 2 base quiquadrado, quiquadrado qui quadrado, quadrado qui-quadrado Student MannWhitney Mann Whitney posthoc post hoc múltiplas Resultados verificaramse verificaram se 0 1 p= p (p 0004 004 0,00 p0001 001 p<0,001 respectivamente (p<0,00 prática. . prática) (p<0,001) obtida Conclusão registro U111112416730. U111112416730 U U1111 1241 6730. 6730 U1111-1241-6730 000 00 0,0 p000 p<0,00 (p<0,0 U11111241673 U111 124 673 U1111-1241-673 p00 p<0,0 (p<0, U1111124167 U11 12 67 U1111-1241-67 p0 p<0, (p<0 U111112416 U1 6 U1111-1241-6 p<0 (p< U11111241 U1111-1241- p< U1111124 U1111-1241 U111112 U1111-124 U11111 U1111-12 U1111-1 U1111-

Objective: to evaluate the effect of an educational video on the knowledge, attitude, and practice of self-care with arteriovenous fistula in patients undergoing hemodialysis treatment. Method: randomized controlled clinical trial, with two arms and single-blind. The intervention used an educational video on arteriovenous fistula self-care. The Fistula Self-Care Knowledge, Attitude, and Practice Scale was applied to 27 renal patients on hemodialysis in the control group and 28 in the intervention group at baseline, after seven and fourteen days. The data was analyzed using the Statistical Package for the Social Sciences software, using the chi-square test, Student’s t-test, Mann-Whitney test, and Friedman’s test with post-hoc analysis for multiple comparisons. Results: there were statistically significant differences in the knowledge and practice of self-care with the fistula at 0, 7 and, 14 days in the intervention (p= 0.004 and p<0.001, respectively) and control groups (p<0.001 for knowledge and practice). Attitude showed a significant difference at follow-up (p<0.001), but the post-hoc analysis did not confirm the significance obtained. Conclusion: patients’ knowledge and practice showed significant increases at follow-up in the control and intervention groups, while the increase in attitude was not significant in either group. Clinical trial, registration number: U1111-1241-6730. Objective selfcare self care treatment Method trial singleblind. singleblind single blind. blind single-blind selfcare. care. SelfCare Self Care Knowledge 2 baseline software chisquare chi square Students Student s ttest, ttest t t-test MannWhitney Mann Whitney Friedmans Friedman posthoc post hoc comparisons Results 0 1 p= p (p 0004 004 0.00 p0001 001 p<0.001 respectively (p<0.00 practice. . practice) followup follow up , (p<0.001) obtained Conclusion number U111112416730. U111112416730 U U1111 1241 6730. 6730 U1111-1241-6730 000 00 0.0 p000 p<0.00 (p<0.0 U11111241673 U111 124 673 U1111-1241-673 0. p00 p<0.0 (p<0. U1111124167 U11 12 67 U1111-1241-67 p0 p<0. (p<0 U111112416 U1 6 U1111-1241-6 p<0 (p< U11111241 U1111-1241- p< U1111124 U1111-1241 U111112 U1111-124 U11111 U1111-12 U1111-1 U1111-

Objetivo: evaluar el efecto de un video educacional en el conocimiento, actitud y práctica del autocuidado de la fístula arteriovenosa de pacientes en tratamiento de hemodiálisis. Método: ensayo clínico aleatorio controlado, con dos brazos y simple ciego. La intervención utilizó un video educacional sobre el autocuidado de la fístula arteriovenosa. Fue aplicada la Escala de conocimiento, actitud y práctica del autocuidado de la fístula en 27 pacientes renales en hemodiálisis del grupo control y en 28 del grupo intervención en la línea de base, después de siete y catorce días. Los datos fueron analizados con el software Statistical Package for the Social Sciences , con la aplicación de las pruebas Chi-cuadrado, T de Student, Mann-Whitney y Test de Friedman, con análisis post-hoc para comparaciones múltiples. Resultados: se verificaron diferencias estadísticamente significativas en el conocimiento y práctica del autocuidado de la fístula en el seguimiento de 0, 7 y 14 días de los grupos intervención (p= 0,004 y p<0,001, respectivamente) y control (p<0,001 para el conocimiento y práctica). La actitud presentó diferencia significativa en el seguimiento (p<0,001), pero el análisis post-hoc no confirmó la significación obtenida. Conclusión: el conocimiento y práctica de los pacientes presentaron aumentos significantes en el seguimiento en los grupos control e intervención, en cuanto que el aumento de la actitud no fue significativo en ninguno de los grupos. Ensayo clínico, número de registro: U1111-1241-6730. Objetivo Método controlado ciego 2 base Chicuadrado, Chicuadrado Chi cuadrado, cuadrado Chi-cuadrado Student MannWhitney Mann Whitney Friedman posthoc post hoc múltiples Resultados 0 1 p= p (p 0004 004 0,00 p0001 001 p<0,001 respectivamente (p<0,00 práctica. . práctica) (p<0,001) obtenida Conclusión registro U111112416730. U111112416730 U U1111 1241 6730. 6730 U1111-1241-6730 000 00 0,0 p000 p<0,00 (p<0,0 U11111241673 U111 124 673 U1111-1241-673 p00 p<0,0 (p<0, U1111124167 U11 12 67 U1111-1241-67 p0 p<0, (p<0 U111112416 U1 6 U1111-1241-6 p<0 (p< U11111241 U1111-1241- p< U1111124 U1111-1241 U111112 U1111-124 U11111 U1111-12 U1111-1 U1111-

https://doi.org/10.1590/1518-8345.6949.4185

11.

The profile of patients with postpartum hemorrhage admitted to the obstetric intensive care: a cross-sectional study care crosssectional cross sectional
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Silva, Mayara dos Santos Farias Ferreira

; Amorim, Melania Maria Ramos de

; Melo, Brena

; Lanza, André Vieira

; Ramos, Maria Eduarda Trigueiro

; Carvalho, Bruna Antunes Durães de

; Tenório, Natalia Nunes

; Katz, Leila

Revista Brasileira de Ginecologia e Obstetrícia

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2024, Volume 46 elocation e-rbgo47

Abstract: En | Text: En | PDF: En

Abstract Objective In Brazil, postpartum hemorrhage (PPH) is a major cause of maternal morbidity and mortality. Data on the profile of women and risk factors associated with PPH are sparse. This study aimed to describe the profile and management of patients with PPH, and the association of risk factors for PPH with severe maternal outcomes (SMO). Methods A cross-sectional study was conducted in Instituto de Medicina Integral Prof. Fernando Figueira (IMIP) obstetric intensive care unit (ICU) between January 2012 and March 2020, including patients who gave birth at the hospital and that were admitted with PPH to the ICU. Results The study included 358 patients, of whom 245 (68.4%) delivered in the IMIP maternity, and 113 (31.6%) in other maternity. The mean age of the patients was 26.7 years, with up to eight years of education (46.1%) and a mean of six prenatal care. Uterine atony (72.9%) was the most common cause, 1.6% estimated blood loss, 2% calculated shock index (SI), 63.9% of patients received hemotransfusion, and 27% underwent hysterectomy. 136 cases of SMO were identified, 35.5% were classified as maternal near miss and 3.0% maternal deaths. Multiparity was associated with SMO as an antepartum risk factor (RR=1.83, 95% CI1.42-2.36). Regarding intrapartum risk factors, abruptio placentae abruption was associated with SMO (RR=2.2 95% CI1.75-2.81). Among those who had hypertension (49.6%) there was a lower risk of developing SMO. Conclusion The principal factors associated with poor maternal outcome were being multiparous and placental abruption. Brazil (PPH mortality sparse . (SMO) crosssectional cross sectional Prof (IMIP ICU (ICU 201 2020 35 24 68.4% 684 68 4 (68.4% maternity 11 31.6% 316 31 6 (31.6% 267 26 7 26. 46.1% 461 46 1 (46.1% 72.9% 729 72 9 (72.9% 16 1.6 loss 2 SI, SI , (SI) 639 63 63.9 hemotransfusion 27 hysterectomy 13 identified 355 5 35.5 30 3 0 3.0 deaths RR=1.83, RR183 RR 83 (RR=1.83 95 CI1.422.36. CI142236 CI CI1.42 2.36 CI1 42 36 CI1.42-2.36) RR=2.2 RR22 (RR=2. CI1.752.81. CI175281 CI1.75 2.81 75 81 CI1.75-2.81) 49.6% 496 49 (49.6% (SMO 20 202 68.4 (68.4 31.6 (31.6 46.1 (46.1 72.9 (72.9 1. (SI 63. 35. 3. RR=1.83 RR18 8 (RR=1.8 422 CI1.422.36 CI14223 CI142 CI1.4 236 2.3 CI1.42-2.36 RR=2. RR2 (RR=2 752 CI1.752.81 CI17528 CI175 CI1.7 281 2.8 CI1.75-2.81 49.6 (49.6 68. (68. 31. (31. 46. (46. 72. (72. RR=1.8 RR1 (RR=1. CI1.422.3 CI1422 CI14 CI1. 23 2. CI1.42-2.3 RR=2 (RR= CI1.752.8 CI1752 CI17 28 CI1.75-2.8 49. (49. (68 (31 (46 (72 RR=1. (RR=1 CI1.422. CI1.42-2. RR= (RR CI1.752. CI1.75-2. (49 (6 (3 (4 (7 RR=1 CI1.422 CI1.42-2 CI1.752 CI1.75-2 ( CI1.42- CI1.75-

https://doi.org/10.61622/rbgo/2024rbgo47

12.

Multiplexed in-Series Macro-Bend Fiber Sensors for Personal Authentication Through Foot Recognition inSeries in Series MacroBend Macro Bend
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Girão, Natália Soares

; Lugarini, Diogo

; Arruda, Lúcia Valéria Ramos de

; Fabris, José Luís

; Muller, Marcia

Journal of Microwaves, Optoelectronics and Electromagnetic Applications

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2024, Volume 23 N. 2 elocation e2024279789

Abstract: En | Text: En | PDF: En

Abstract This work proposes a new tactile sensing system for biometric authentication. The system operates based on the response of multiplexed optical fiber macro-bend sensors to plantar pressure. The setup contains a set of 6 in-series sensors installed in holes drilled in a foot-shaped slab of Polymethyl Methacrylate. Each sensor is a loop of standard single-mode telecommunication fiber with 2.5 mm radius, encapsulated with silicone elastomer. The instrumentation required for interrogation includes only a broadband visible light source and a ultraviolet-visible spectrometer. Personal authentication is based on recognizing the unique pattern of pressures applied by the person’s foot in the metatarsal, outside of the foot arch, and heel areas monitored by the 6 sensors. The light spectrum transmitted by the set of multiplexed sensors in the spectral range from 400 nm to 800 nm carries information about the magnitude of the pressure applied on each sensor by the foot. The distribution of pressures exerted by different individuals alters the geometry of the macro-bends, resulting in spectral changes in transmitted light that allow personal authentication. Principal component analysis and support vector machine method are responsible for foot recognition. Data analysis returned hit rates greater than 85% for 6 different feet. macrobend macro bend inseries series footshaped shaped Methacrylate singlemode single mode 25 2 5 2. radius elastomer ultravioletvisible ultraviolet spectrometer persons person s metatarsal arch 40 80 macrobends, macrobends bends, bends macro-bends recognition 85 feet 4 8

https://doi.org/10.1590/2179-10742024v23i2279789

13.

Oclusão da artéria central da retina por embolia gordurosa após injeção facial de gordura autóloga
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Hueb, Denis Cardoso

; Rezende, Gabriela Xavier

; Pimenta, Natália D’arc Queiroz

; da Silva, Aline Ramos

; Pachon, Suzy Cunha

Revista Brasileira de Oftalmologia

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2024, Volume 83 elocation e0038

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Com o crescimento da indústria cosmética global, a busca pela estética e pelo rejuvenescimento impulsionou o aumento de procedimentos estéticos. A gordura autóloga é o tipo de preenchimento mais comum e mais grave relacionado à cegueira iatrogênica. A oclusão iatrogênica da artéria oftálmica é uma complicação rara (mas devastadora) das injeções de preenchimento facial. Embora diversos tratamentos tenham sido relatados e propostos, até o momento não há eficácia comprovada. Na identificação da oclusão de artéria central da retina, o tempo é de fundamental importância para o prognóstico visual do paciente. Os resultados, em geral, são insatisfatórios, e há pouca ou nenhuma evidência favorável. O objetivo deste trabalho foi relatar o caso de uma paciente que apresentou oclusão de artéria central da retina após procedimento cosmético com gordura autóloga em região nasolabial. global estéticos mas devastadora facial propostos comprovada resultados geral insatisfatórios favorável nasolabial

ABSTRACT The global cosmetic industry growth and the desire for aesthetics and rejuvenation have increased the aesthetic procedures. Autologous fat is the most common and most serious type of filling related to iatrogenic blindness. Iatrogenic occlusion of the ophthalmic artery is a rare but devastating complication of facial filler injections. Although several treatments have been reported and proposed, to date there is no proven efficacy. In identifying central retinal artery occlusion, timing is crucial to the patient’s visual prognosis. The results, in general, are unsatisfactory and there is little or no favorable evidence. This paper aimed to report the case of a patient who presented central retinal artery occlusion after a cosmetic procedure with autologous fat in the nasolabial region. procedures blindness injections proposed efficacy patients s prognosis results general evidence region

https://doi.org/10.37039/1982.8551.20240038

14.

Evaluation of virulence factors in clinical isolates of pathogenic E. coli in avian samples in Caloto, Colombia
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Durango Galván, Harold Eduardo Morales López, Hernando Murillo Ramos, Enderson Yepes Blandón, Jonny Andrés Campo Nieto, Omer Quiroz Torres, Kelly Natalia Echeverri Tirado, Laura Catalina Villarreal Julio, Rafael Guillermo

Revista Colombiana de Biotecnología

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dec 2023, Volume 25 N. 2 Pages 33 - 49

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN La E. coli patógena aviar (APEC), produce una infección extraintestinal en pollos, pavos y otros tipos de aves, denominada colibacilosis, la cual es considerada una de las principales causas de pérdidas económicas por morbilidad, mortalidad y descarte de canales de aves. El objetivo del presente estudio fue caracterizar el perfil genético de los factores de virulencia de diferentes aislamientos de E. coli aviar en Caloto, Cauca, Colombia. Materiales y métodos: E. coli se aisló e identificó mediante pruebas bioquímicas, a partir de 47 aislamientos clínicos. Posteriormente, el ADN se extrajo utilizando Chelex. Se diseñaron tres PCR multiplex para amplificar 13 factores de virulencia (iroN, hlyF, iss, iutA, frz, vat, sitA, KpsM, sitD, fimH, pstB, sopB y uvrY), utilizando primers informados previamente para cada uno. Al final, los productos de amplificación fueron verificados en geles de agarosa. Cada aislamiento se clasificó según el número de factores de virulencia: grupo A (entre 10 y 13), grupo B (entre 5 y 9) y grupo C (4 o menos). Discusión y Conclusiones: pudimos identificar la presencia de un grupo de factores de virulencia en los aislados clínicos de APEC, lo que nos permite demostrar que tanto la frecuencia como el perfil de los factores de virulencia en las cepas aisladas presentaron un perfil diferente al reportado por otros autores. Los genes de virulencia pstB y fimH se detectaron en todas nuestras muestras, siendo el gen iss el de menor frecuencia. Finalmente, según el número de factores de virulencia, el grupo A fue el más frecuente.

ABSTRACT Avian pathogenic E. coli (APEC), produces an extraintestinal infection in chickens, turkeys, and other types of birds, called colibacillosis, which is considered one of the main causes of economic losses due to morbidity, mortality, and discard of poultry carcasses. The objective of the present study was to characterize the genetic profile of the virulence factors of different isolates of avian E. coli in Caloto, Cauca, Colombia. Materials and methods: E. coli was isolated and identified by biochemical tests, from 47 clinical isolates. Subsequently, the DNA was extracted using Chelex. Three multiplex PCRs were designed to amplify 13 virulence factors (iroN, hlyF, iss, iutA, frz, vat, sitA, KpsM, sitD, fimH, pstB, sopB, and uvrY), using primers previously reported for each. At the end, the amplification products were verified on agarose gels. Each isolate was classified according to the number of virulence factors: group A (between 10 and 13), group B (between 5 and 9), and group C (4 or less). Discussion and Conclusions: we were able to identify the presence of a group of virulence factors in clinical isolates of APEC, which allows us to demonstrate that both the frequency and the profile of virulence factors in the isolated strains showed a different profile than the reported by other authors. The virulence genes pstB and fimH were detected in all our samples, and the iss gene was the one with the lowest frequency. Finally, according to the number of virulence factors, the group A was the most frequent.

https://doi.org/10.15446/rev.colomb.biote.v25n2.110727

15.

Reporte del primer caso de infección por Lawsonella clevelandensis en Latinoamérica y revisión de literatura
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Zavadzki, Giovanna Reyes Barros, Tomás Sarfatis Feige, Alberto Granada Castaño, Jaime Kobus Garin, Valentina Ramos-Rojas, José Bigossi Aguiar, Natália Inzunza Robles, José

Revista médica de Chile

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jul 2023, Volume 151 N. 7 Pages 941 - 946

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN Lawsonella clevelandensis es un bacilo anaerobio Gram positivo, parcialmente ácido-alcohol resistente, perteneciente al orden Corynebacteriales y considerado comensal de la piel y la cavidad bucal. En los últimos años se han reportado escasos casos de infección por este microorganismo, generalmente en pacientes inmunosuprimidos, siendo la presentación clínica más común la generación de abscesos. El aislamiento de esta bacteria es difícil ya que no crece en los medios de cultivo tradicionales, por lo que su identificación requiere habitualmente del uso de biología molecular. Presentamos el caso de una paciente de 29 años con trasplante renal y empeoramiento progresivo de la función renal en contexto de una vasculitis pauciinmune con requerimiento de mayor inmunosupresión. En el laboratorio destacaba leucocituria asintomática, con urocultivo negativo, por lo que se realizaron 7 baciloscopias en orina, con resultados positivos en 3, pero con PCR de M. tuberculosis y cultivo de micobacterias negativo. Se realizó secuenciación del gen que codifica para el ARN 16s del ribosoma bacteriano a partir de una muestra de orina, obteniéndose una secuencia compatible con Lawsonella clevelandensis. Tras el resultado, se indicó terapia con amoxicilina-ácido clavulánico por 7 meses. A conocimiento de los autores, este es el duodécimo caso de infección por Lawsonella clevelandensis descrito en la literatura médica y el primero que reporta el aislamiento del patógeno en la orina.

Lawsonella clevelandensis is a gram-positive anaerobic bacillus, partially acid-fast, belonging to the order Corynebacteriales and is considered commensal of the skin and oral cavity. In recent years, few cases of infection by this microorganism have been reported, generally in immunosuppressed patients, with the most reported clinical presentation being the generation of abscesses. The isolation of this bacterium is difficult since it does not grow in traditional cultures, so its identification usually requires the use of molecular biology. We present the case of a 29-year-old patient with a kidney transplant and progressive worsening of kidney function in the context of a pauci-immune vasculitis which required greater immunosuppression. During the investigation, it was identified an asymptomatic leukocyturia, with a negative urine culture, for which six urine smear microscopy tests were performed of which 3 were positive, but with a negative Koch culture. Sequencing of the gene that codes for the 16s RNA of the bacterial ribosome was performed from a urine sample, obtaining a sequence compatible with Lawsonella clevelandensis. After the result, therapy with amoxicillin-clavulanic acid was indicated with resolution of the leukocyturia and negative smear microscopy, and immunosuppression could be indicated without inconvenience. To the authors’ knowledge, this is the twelfth case of Lawsonella clevelandensis infection described in the medical literature in the world and the first to report the isolation of the pathogen in urine.

https://doi.org/10.4067/s0034-98872023000700941

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