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1.
Dynapenia and sarcopenia: association with the diagnosis, duration and complication of type 2 diabetes mellitus in ELSA-Brasil
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Santos, Débora Noara Duarte dos
; Coelho, Carolina Gomes
; Diniz, Maria de Fátima Haueisen Sander
; Duncan, Bruce Bartholow
; Schmidt, Maria Inês
; Bensenor, Isabela Judith Martins
; Szlejf, Claudia
; Telles, Rosa Weiss
; Barreto, Sandhi Maria
.
Abstract: Sarcopenia (the loss of muscle mass, strength and skeletal muscle function) increases mortality and the risk of hospitalization in the older population. Although it is known that older adults with type 2 diabetes mellitus (T2DM) have a higher risk of dynapenia and sarcopenia, few studies have investigated these conditions in middle-aged populations. The objective of this study was to investigate whether T2DM, its duration, the presence of albuminuria, and glycemic control are associated with sarcopenia and its components in adults. The cross-sectional analysis was based on data from visit 2 of the Brazilian Longitudinal Study of Adult Health (2012-2014). The 2018 European Working Group on Sarcopenia in Older People criteria were used to define dynapenia, low appendicular muscle mass (LAMM), and sarcopenia (absent/probable/confirmed). The explanatory variables were: T2DM; duration of T2DM; T2DM according to the presence of albuminuria; and glycemic control (HbA1C < 7%) among people with T2DM. A total of 12,132 participants (mean age = 55.5, SD: 8.9 years) were included. The odds ratio for LAMM was greater among those with T2DM, T2DM duration from 5 to 10 years, and T2DM without albuminuria. Chances of dynapenia were higher among those with T2DM, T2DM duration > 10 years, and T2DM with and without albuminuria. The variables T2DM, T2DM ≥ 10 years, and T2DM with albuminuria increased the odds of probable sarcopenia, and T2DM duration from 5 to 10 years increased the odds of confirmed sarcopenia. The results support the importance of frequently monitoring the musculoskeletal mass and strength of individuals with T2DM to prevent sarcopenia and related outcomes.
Resumen: La sarcopenia (pérdida de masa muscular, fuerza y función muscular esquelética) aumenta la mortalidad y el riesgo de hospitalización en ancianos. Los ancianos con diabetes mellitus tipo 2 (DMT2) presentan un mayor riesgo de sufrir dinapenia y sarcopenia, pero pocos estudios han investigado poblaciones de mediana edad. El objetivo fue investigar si la DMT2, su duración, la presencia de albuminuria y el control glucémico están asociados con la sarcopenia y sus componentes en adultos. Análisis transversal basado en los datos de la visita 2 del Estudio Longitudinal de Salud del Adulto en Brasil (2012-2014). Se utilizaron los criterios del European Working Group on Sarcopenia in Older People [Grupo de Trabajo Europeo sobre Sarcopenia en Personas Mayores] del 2018 para definir dinapenia, baja masa muscular apendicular y sarcopenia (ausente/probable/confirmada). Las variables explicativas fueron las siguientes: DMT2; duración de la DMT2; DMT2 según la presencia de albuminuria; y control glucémico (HbA1c < 7%) entre personas con DMT2. Se incluyeron 12.132 participantes (edad media = 55,5, DE: 8,9 años). La razón de probabilidades de masa muscular apendicular baja fue mayor entre personas con DMT2, duración de la DMT2 entre 5 y 10 años y DMT2 sin albuminuria. Las probabilidades de dinapenia fueron mayores entre las personas con DMT2, duración de la DMT2 > 10 años y DMT2 con y sin albuminuria. Las condiciones de DMT2, DMT2 ≥ 10 años y DMT2 con albuminuria aumentaron las probabilidades de sarcopenia probable y la duración de la DMT2 entre 5 y 10 años las probabilidades de sarcopenia confirmada. Los resultados refuerzan la importancia del monitoreo frecuente de la masa y de la fuerza musculoesquelética en individuos con DMT2 para prevenir la sarcopenia y los desenlaces relacionados.
Resumo: A sarcopenia (perda de massa muscular, força e função muscular esquelética) aumenta a mortalidade e o risco de hospitalização em idosos. Idosos com diabetes mellitus tipo 2 (DMT2) apresentam risco elevado de desenvolver dinapenia e sarcopenia, mas poucos estudos investigaram populações de meia-idade. O objetivo foi investigar se DMT2, sua duração, a presença de albuminúria e o controle glicêmico estão associados à sarcopenia e seus componentes em adultos. Análise transversal baseada nos dados da segunda visita do Estudo Longitudinal de Saúde do Adulto (2012-2014). Os critérios do European Working Group on Sarcopenia in Older People [Grupo de Trabalho Europeu sobre Sarcopenia em Pessoas Idosas] de 2018 foram usados para definir dinapenia, baixa massa muscular apendicular e sarcopenia (ausente/provável/confirmada). As variáveis explicativas foram: DMT2; duração do DMT2; DMT2 de acordo com a presença de albuminúria; e controle glicêmico (HbA1c < 7%) entre pessoas com DMT2. Foram incluídos 12.132 participantes (idade média de 55,5; DP: 8,9 anos). A razão de chances para baixa massa muscular apendicular foi maior entre pessoas com DMT2, duração do DMT2 entre 5 e 10 anos e DMT2 sem albuminúria. As chances de dinapenia foram maiores entre pessoas com DMT2, duração do DMT2 > 10 anos e DMT2 com e sem albuminúria. DMT2, DMT2 ≥ 10 anos e DMT2 com albuminúria aumentaram as chances de sarcopenia provável e duração do DMT2 entre 5 e 10 anos aumentaram as chances de sarcopenia confirmada. Os resultados reforçam a importância do monitoramento frequente da massa e da força muscular em indivíduos com DMT2 para prevenir a sarcopenia e desfechos relacionados.
2.
Dynapenia and sarcopenia: association with the diagnosis, duration and complication of type 2 diabetes mellitus in ELSA-Brasil sarcopenia diagnosis ELSABrasil ELSA Brasil
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Santos, Débora Noara Duarte dos
; Coelho, Carolina Gomes
; Diniz, Maria de Fátima Haueisen Sander
; Duncan, Bruce Bartholow
; Schmidt, Maria Inês
; Bensenor, Isabela Judith Martins
; Szlejf, Claudia
; Telles, Rosa Weiss
; Barreto, Sandhi Maria
.
Resumo: A sarcopenia (perda de massa muscular, força e função muscular esquelética) aumenta a mortalidade e o risco de hospitalização em idosos. Idosos com diabetes mellitus tipo 2 (DMT2) apresentam risco elevado de desenvolver dinapenia e sarcopenia, mas poucos estudos investigaram populações de meia-idade. O objetivo foi investigar se DMT2, sua duração, a presença de albuminúria e o controle glicêmico estão associados à sarcopenia e seus componentes em adultos. Análise transversal baseada nos dados da segunda visita do Estudo Longitudinal de Saúde do Adulto (2012-2014). Os critérios do European Working Group on Sarcopenia in Older People [Grupo de Trabalho Europeu sobre Sarcopenia em Pessoas Idosas] de 2018 foram usados para definir dinapenia, baixa massa muscular apendicular e sarcopenia (ausente/provável/confirmada). As variáveis explicativas foram: DMT2; duração do DMT2; DMT2 de acordo com a presença de albuminúria; e controle glicêmico (HbA1c < 7%) entre pessoas com DMT2. Foram incluídos 12.132 participantes (idade média de 55,5; DP: 8,9 anos). A razão de chances para baixa massa muscular apendicular foi maior entre pessoas com DMT2, duração do DMT2 entre 5 e 10 anos e DMT2 sem albuminúria. As chances de dinapenia foram maiores entre pessoas com DMT2, duração do DMT2 > 10 anos e DMT2 com e sem albuminúria. DMT2, DMT2 ≥ 10 anos e DMT2 com albuminúria aumentaram as chances de sarcopenia provável e duração do DMT2 entre 5 e 10 anos aumentaram as chances de sarcopenia confirmada. Os resultados reforçam a importância do monitoramento frequente da massa e da força muscular em indivíduos com DMT2 para prevenir a sarcopenia e desfechos relacionados. Resumo perda esquelética idosos DMT (DMT2 meiaidade. meiaidade meia idade. idade meia-idade adultos 20122014. 20122014 2012 2014 . (2012-2014) Grupo Idosas 201 ausente/provável/confirmada. ausenteprovávelconfirmada ausente/provável/confirmada ausente confirmada (ausente/provável/confirmada) HbA1c HbAc HbA c 7% 7 12132 12 132 12.13 55,5 555 55 DP 89 8 9 8, anos. anos) 1 relacionados (DMT 2012201 (2012-2014 20 (ausente/provável/confirmada 1213 13 12.1 55, 201220 (2012-201 121 12. 20122 (2012-20 (2012-2 (2012- (2012 (201 (20 (2 (
Abstract: Sarcopenia (the loss of muscle mass, strength and skeletal muscle function) increases mortality and the risk of hospitalization in the older population. Although it is known that older adults with type 2 diabetes mellitus (T2DM) have a higher risk of dynapenia and sarcopenia, few studies have investigated these conditions in middle-aged populations. The objective of this study was to investigate whether T2DM, its duration, the presence of albuminuria, and glycemic control are associated with sarcopenia and its components in adults. The cross-sectional analysis was based on data from visit 2 of the Brazilian Longitudinal Study of Adult Health (2012-2014). The 2018 European Working Group on Sarcopenia in Older People criteria were used to define dynapenia, low appendicular muscle mass (LAMM), and sarcopenia (absent/probable/confirmed). The explanatory variables were: T2DM; duration of T2DM; T2DM according to the presence of albuminuria; and glycemic control (HbA1C < 7%) among people with T2DM. A total of 12,132 participants (mean age = 55.5, SD: 8.9 years) were included. The odds ratio for LAMM was greater among those with T2DM, T2DM duration from 5 to 10 years, and T2DM without albuminuria. Chances of dynapenia were higher among those with T2DM, T2DM duration > 10 years, and T2DM with and without albuminuria. The variables T2DM, T2DM ≥ 10 years, and T2DM with albuminuria increased the odds of probable sarcopenia, and T2DM duration from 5 to 10 years increased the odds of confirmed sarcopenia. The results support the importance of frequently monitoring the musculoskeletal mass and strength of individuals with T2DM to prevent sarcopenia and related outcomes. Abstract function population TDM T DM (T2DM middleaged middle aged populations crosssectional cross sectional 20122014. 20122014 2012 2014 . (2012-2014) 201 LAMM, , (LAMM) absent/probable/confirmed. absentprobableconfirmed absent/probable/confirmed absent (absent/probable/confirmed) HbA1C HbAC HbA C 7% 7 12132 12 132 12,13 mean 555 55 55.5 SD 89 8 9 8. included 1 outcomes 2012201 (2012-2014 20 (LAMM (absent/probable/confirmed 1213 13 12,1 55. 201220 (2012-201 121 12, 20122 (2012-20 (2012-2 (2012- (2012 (201 (20 (2 (
Resumen: La sarcopenia (pérdida de masa muscular, fuerza y función muscular esquelética) aumenta la mortalidad y el riesgo de hospitalización en ancianos. Los ancianos con diabetes mellitus tipo 2 (DMT2) presentan un mayor riesgo de sufrir dinapenia y sarcopenia, pero pocos estudios han investigado poblaciones de mediana edad. El objetivo fue investigar si la DMT2, su duración, la presencia de albuminuria y el control glucémico están asociados con la sarcopenia y sus componentes en adultos. Análisis transversal basado en los datos de la visita 2 del Estudio Longitudinal de Salud del Adulto en Brasil (2012-2014). Se utilizaron los criterios del European Working Group on Sarcopenia in Older People [Grupo de Trabajo Europeo sobre Sarcopenia en Personas Mayores] del 2018 para definir dinapenia, baja masa muscular apendicular y sarcopenia (ausente/probable/confirmada). Las variables explicativas fueron las siguientes: DMT2; duración de la DMT2; DMT2 según la presencia de albuminuria; y control glucémico (HbA1c < 7%) entre personas con DMT2. Se incluyeron 12.132 participantes (edad media = 55,5, DE: 8,9 años). La razón de probabilidades de masa muscular apendicular baja fue mayor entre personas con DMT2, duración de la DMT2 entre 5 y 10 años y DMT2 sin albuminuria. Las probabilidades de dinapenia fueron mayores entre las personas con DMT2, duración de la DMT2 > 10 años y DMT2 con y sin albuminuria. Las condiciones de DMT2, DMT2 ≥ 10 años y DMT2 con albuminuria aumentaron las probabilidades de sarcopenia probable y la duración de la DMT2 entre 5 y 10 años las probabilidades de sarcopenia confirmada. Los resultados refuerzan la importancia del monitoreo frecuente de la masa y de la fuerza musculoesquelética en individuos con DMT2 para prevenir la sarcopenia y los desenlaces relacionados. Resumen pérdida esquelética DMT (DMT2 edad adultos 20122014. 20122014 2012 2014 . (2012-2014) Grupo Mayores 201 ausente/probable/confirmada. ausenteprobableconfirmada ausente/probable/confirmada ausente confirmada (ausente/probable/confirmada) siguientes HbA1c HbAc HbA c 7% 7 12132 12 132 12.13 555 55 55,5 DE 89 8 9 8, años. años) 1 relacionados (DMT 2012201 (2012-2014 20 (ausente/probable/confirmada 1213 13 12.1 55, 201220 (2012-201 121 12. 20122 (2012-20 (2012-2 (2012- (2012 (201 (20 (2 (
3.
Postorotracheal intubation dysphagia in patients with COVID-19: A retrospective study COVID19 COVID 19 COVID-19 COVID1 1 COVID-1 COVID-
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Saconato, Mariana
; Maselli-Schoueri, Jean Henri
; Malaque, Ceila Maria Sant’Ana
; Marcusso, Rosa Maria
; Oliveira, Augusto César Penalva de
; Batista, Lucio Antonio Nascimento
; Ultramari, Graziela
; Lindoso, José Angelo Lauletta
; Gonçalves, Maria Inês Rebelo
; Sztajnbok, Jaques
.
ABSTRACT BACKGROUND: The cause of oropharyngeal dysphagia in patients with coronavirus disease (COVID-19) can be multifactorial and may underly limitations in swallowing rehabilitation. OBJECTIVE: Analyze the factors related to dysphagia in patients with COVID-19 immediately after orotracheal extubation and the factors that influence swallowing rehabilitation. DESIGN AND SETTING: A retrospective study. METHODS: The presence of dysphagia was evaluated using the American Speech-Language Hearing Association National Outcome Measurement System (ASHA NOMS) scale and variables that influenced swallowing rehabilitation in 140 adult patients who required invasive mechanical ventilation for >48 h. RESULTS: In total, 46.43% of the patients scored 1 or 2 on the ASHA NOMS (severe dysphagia) and 39.29% scored 4 (single consistency delivered orally) or 5 (exclusive oral diet with adaptations). Both the length of mechanical ventilation and the presence of neurological disorders were associated with lower ASHA NOMS scores (odds ratio [OR]: 0.80, 95% confidence interval [CI]: 0.74–0.87 P < 0.05; and OR: 0.13, 95% CI: 0.61–0.29; P < 0.05, respectively). Age and the presence of tracheostomy were negatively associated with speech rehabilitation (OR: 0.92; 95% CI: 0.87–−0.96; OR: 0.24; 95% CI: 0.80–−0.75), and acute post-COVID-19 kidney injury requiring dialysis and lower scores on the ASHA NOMS were associated with longer time for speech therapy outcomes (β: 1.62, 95% CI, 0.70–3.17, P < 0.001; β: −1.24, 95% CI: −1.55–−0.92; P < 0.001). CONCLUSION: Prolonged orotracheal intubation and post-COVID-19 neurological alterations increase the probability of dysphagia immediately after extubation. Increased age and tracheostomy limited rehabilitation. BACKGROUND COVID19 COVID 19 (COVID-19 OBJECTIVE COVID-1 SETTING study METHODS SpeechLanguage Speech Language 14 48 >4 h RESULTS total 4643 46 43 46.43 severe 3929 39 29 39.29 single orally exclusive adaptations. adaptations . adaptations) odds OR [OR] 080 0 80 0.80 95 CI [CI] 074087 74 87 0.74–0.8 0.05 005 05 013 13 0.13 0.61–0.29 061029 61 respectively. respectively respectively) (OR 0.92 092 92 0.87–−0.96 087096 96 0.24 024 24 0.80–−0.75, 080075 0.80–−0.75 , 75 0.80–−0.75) postCOVID19 postCOVID post post-COVID-1 β (β 162 62 1.62 070317 70 3 17 0.70–3.17 0.001 0001 001 124 −1.24 −1.55–−0.92 155092 55 0.001. 0.001) CONCLUSION COVID1 (COVID-1 COVID- > 464 46.4 392 39.2 [OR 08 8 0.8 9 [CI 07408 7 0.74–0. 0.0 00 01 0.1 0.61–0.2 06102 6 0.9 09 0.87–−0.9 08709 0.2 02 08007 0.80–−0.7 postCOVID1 post-COVID- 16 1.6 07031 0.70–3.1 0.00 000 12 −1.2 −1.55–−0.9 15509 (COVID- 46. 39. 0. 0740 0.74–0 0.61–0. 0610 0.87–−0. 0870 0800 0.80–−0. post-COVID 1. 0703 0.70–3. −1. −1.55–−0. 1550 (COVID 074 0.74– 0.61–0 061 0.87–−0 087 0.80–−0 070 0.70–3 −1 −1.55–−0 155 07 0.74 0.61– 06 0.87–− 0.80–− 0.70– − −1.55–− 15 0.7 0.61 0.87– 0.80– 0.70 −1.55– 0.6 0.87 −1.55 −1.5
4.
Mycobacterium tuberculosis latent infection in healthcare students: systematic review of prevalence students
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Lima, Renata Silva de
; Silva, Rodrigo Nogueira da
; André, Suzana Rosa
; Pinheiro, Ana Kedma Correa
; Sousa, Ana Inês
; Silva, Ingrid Fabiane Santos da
; Santos, Juliano dos
; Nogueira, Laura Maria Vidal
; Zeitoune, Regina Célia Gollner
.
RESUMO Objetivo: O objetivo deste estudo foi sintetizar as evidências sobre a prevalência de infecção de Mycobacterium tuberculosis (ILTB) entre estudantes de graduação da área da saúde. Método: Foi realizada uma revisão sistemática de prevalência com metanálise. Coortes prospectivas e retrospectivas e estudos transversais envolvendo provável exposição a M. tuberculosis durante a graduação, juntamente com o teste tuberculínico (TT) ou ensaio de liberação de interferon-γ (IGRA) para investigação de tuberculose latente foram pesquisados. As buscas foram realizadas nas bases de dados MEDLINE, CINAHL, EMBASE, LILACS, Scopus e Web of Science. Revisores independentes foram responsáveis pela seleção e inclusão dos estudos. Os dados foram extraídos, avaliados criticamente e sintetizados utilizando a abordagem JBI. PRISMA foi usado para relatar o estudo. Resultados: Vinte e dois estudos foram analisados. A prevalência geral em estudantes de graduação da área da saúde foi de 12,53%. Conclusão: A prevalência de ILTB em estudantes de graduação em saúde foi alta para uma população com alto nível de escolaridade. Triagem com TT e/ou IGRA e quimioprofilaxia, quando necessária, deve ser fornecida aos estudantes de graduação da área da saúde quando em contato com pacientes sintomáticos respiratórios. Objetivo (ILTB Método metanálise M (TT interferonγ interferon γ (IGRA pesquisados MEDLINE CINAHL EMBASE LILACS Science extraídos JBI Resultados analisados 1253 12 53 12,53% Conclusão escolaridade eou quimioprofilaxia necessária respiratórios 125 1 5 12,53 12,5 12,
ABSTRACT Objective: The aim of this study was to synthesize the evidence on the prevalence of latent Mycobacterium tuberculosis infection (LTBI) among undergraduate health care students. Methods: A systematic review of prevalence with meta-analysis was conducted. Prospective and retrospective cohorts and cross-sectional studies involving probable exposure to M. tuberculosis during undergraduate education, along with the tuberculin skin test (TST) or interferon-γ release assay (IGRA) for investigation of latent tuberculosis were searched. Searches were conducted in MEDLINE, CINAHL, EMBASE, LILACS, Scopus, and Web of Science databases. Independent reviewers were responsible for the selection and inclusion of studies. Data were extracted, critically appraised, and synthesized using the JBI approach. PRISMA was used to report the study. Results: Twenty-two studies were analyzed. The overall prevalence in healthcare undergraduate students was 12.53%. Conclusion: The prevalence of LTBI in undergraduate health students was high for such a highly educated population. Screening with TST and/or IGRA and chemoprophylaxis, when necessary, should be provided to undergraduate health students when in contact with respiratory symptomatic patients. Objective (LTBI Methods metaanalysis meta analysis crosssectional cross sectional M education (TST interferonγ interferon γ (IGRA searched MEDLINE CINAHL EMBASE LILACS Scopus databases extracted appraised approach Results Twentytwo Twenty two analyzed 1253 12 53 12.53% Conclusion population andor chemoprophylaxis necessary patients 125 1 5 12.53 12.5 12.
RESUMEN Objetivo: El objetivo de este estudio fue sintetizar la evidencia sobre la prevalencia de infección latente por Mycobacterium tuberculosis (ILTB) entre estudiantes universitarios de la salud. Métodos: Se realizó una revisión sistemática de la prevalencia con metanálisis. Cohortes prospectivas y retrospectivas y estudios transversales que involucran exposición probable a M tuberculosis durante la educación universitaria, junto con la prueba cutánea de tuberculina (TST) o el ensayo de liberación de interferón-γ (IGRA) para la investigación de tuberculosis latente. Las búsquedas se realizaron en las bases de datos MEDLINE, CINAHL, EMBASE, LILACS, Scopus y Web of Science. Revisores independientes fueron responsables de la selección e inclusión de los estudios. Los datos se extrajeron, se evaluaron críticamente y se sintetizaron utilizando el enfoque JBI. Se utilizó PRISMA para informar el estudio. Resultados: Se analizaron veintidós estudios. La prevalencia global en estudiantes universitarios en salud fue del 12,53%. Conclusión: La prevalencia de LTBI en estudiantes universitarios de salud fue alta para una población con un nivel educativo tan alto. Se debe proporcionar tamizaje con TST y/o IGRA y quimioprofilaxis, cuando sea necesario, a los estudiantes universitarios en salud cuando estén en contacto con pacientes sintomáticos respiratorios. Objetivo ILTB (ILTB Métodos metanálisis universitaria (TST interferónγ interferón γ (IGRA MEDLINE CINAHL EMBASE LILACS Science extrajeron JBI Resultados 1253 12 53 12,53% Conclusión alto yo quimioprofilaxis necesario respiratorios 125 1 5 12,53 12,5 12,
5.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
; Linzmeier, Adelita M.
; Calor, Adolfo R.
; Garda, Adrian A.
; Kury, Adriano B.
; Fernandes, Agatha C.S.
; Agudo-Padrón, Aisur I.
; Akama, Alberto
; Silva Neto, Alberto M. da
; Burbano, Alejandro L.
; Menezes, Aleksandra
; Pereira-Colavite, Alessandre
; Anichtchenko, Alexander
; Lees, Alexander C.
; Bezerra, Alexandra M.R.
; Domahovski, Alexandre C.
; Pimenta, Alexandre D.
; Aleixo, Alexandre L.P.
; Marceniuk, Alexandre P.
; Paula, Alexandre S. de
; Somavilla, Alexandre
; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
; Santos, Aline B. dos
; Tassi, Aline D.
; Aragão, Allan C.
; Santos, Allan P.M.
; Migotto, Alvaro E.
; Mendes, Amanda C.
; Cunha, Amanda
; Chagas Júnior, Amazonas
; Sousa, Ana A.T. de
; Pavan, Ana C.
; Almeida, Ana C.S.
; Peronti, Ana L.B.G.
; Henriques-Oliveira, Ana L.
; Prudente, Ana L.
; Tourinho, Ana L.
; Pes, Ana M.O.
; Carmignotto, Ana P.
; Wengrat, Ana P.G. da Silva
; Dornellas, Ana P.S.
; Molin, Anamaria Dal
; Puker, Anderson
; Morandini, André C.
; Ferreira, André da S.
; Martins, André L.
; Esteves, André M.
; Fernandes, André S.
; Roza, André S.
; Köhler, Andreas
; Paladini, Andressa
; Andrade, Andrey J. de
; Pinto, Ângelo P.
; Salles, Anna C. de A.
; Gondim, Anne I.
; Amaral, Antonia C.Z.
; Rondón, Antonio A.A.
; Brescovit, Antonio
; Lofego, Antônio C.
; Marques, Antonio C.
; Macedo, Antonio
; Andriolo, Artur
; Henriques, Augusto L.
; Ferreira Júnior, Augusto L.
; Lima, Aurino F. de
; Barros, Ávyla R. de A.
; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
; Santos, Bernardo F.
; Ferraz, Bernardo R.
; Rosa, Brunno B.
; Sampaio, Brunno H.L.
; Bellini, Bruno C.
; Clarkson, Bruno
; Oliveira, Bruno G. de
; Corrêa, Caio C.D.
; Martins, Caleb C.
; Castro-Guedes, Camila F. de
; Souto, Camilla
; Bicho, Carla de L.
; Cunha, Carlo M.
; Barboza, Carlos A. de M.
; Lucena, Carlos A.S. de
; Barreto, Carlos
; Santana, Carlos D.C.M. de
; Agne, Carlos E.Q.
; Mielke, Carlos G.C.
; Caetano, Carlos H.S.
; Flechtmann, Carlos H.W.
; Lamas, Carlos J.E.
; Rocha, Carlos
; Mascarenhas, Carolina S.
; Margaría, Cecilia B.
; Waichert, Cecilia
; Digiani, Celina
; Haddad, Célio F.B.
; Azevedo, Celso O.
; Benetti, Cesar J.
; Santos, Charles M.D. dos
; Bartlett, Charles R.
; Bonvicino, Cibele
; Ribeiro-Costa, Cibele S.
; Santos, Cinthya S.G.
; Justino, Cíntia E.L.
; Canedo, Clarissa
; Bonecker, Claudia C.
; Santos, Cláudia P.
; Carvalho, Claudio J.B. de
; Gonçalves, Clayton C.
; Galvão, Cleber
; Costa, Cleide
; Oliveira, Cléo D.C. de
; Schwertner, Cristiano F.
; Andrade, Cristiano L.
; Pereira, Cristiano M.
; Sampaio, Cristiano
; Dias, Cristina de O.
; Lucena, Daercio A. de A.
; Manfio, Daiara
; Amorim, Dalton de S.
; Queiroz, Dalva L. de
; Queiroz, Dalva L. de
; Colpani, Daniara
; Abbate, Daniel
; Aquino, Daniel A.
; Burckhardt, Daniel
; Cavallari, Daniel C.
; Prado, Daniel de C. Schelesky
; Praciano, Daniel L.
; Basílio, Daniel S.
; Bená, Daniela de C.
; Toledo, Daniela G.P. de
; Takiya, Daniela M.
; Fernandes, Daniell R.R.
; Ament, Danilo C.
; Cordeiro, Danilo P.
; Silva, Darliane E.
; Pollock, Darren A.
; Muniz, David B.
; Gibson, David I.
; Nogueira, David S.
; Marques, Dayse W.A.
; Lucatelli, Débora
; Garcia, Deivys M.A.
; Baêta, Délio
; Ferreira, Denise N.M.
; Rueda-Ramírez, Diana
; Fachin, Diego A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Pádua, Diego G. de
; Barbosa, Diego N.
; Dolibaina, Diego R.
; Amaral, Diogo C.
; Chandler, Donald S.
; Maccagnan, Douglas H.B.
; Caron, Edilson
; Carvalho, Edrielly
; Adriano, Edson A.
; Abreu Júnior, Edson F. de
; Pereira, Edson H.L.
; Viegas, Eduarda F.G.
; Carneiro, Eduardo
; Colley, Eduardo
; Eizirik, Eduardo
; Santos, Eduardo F. dos
; Shimbori, Eduardo M.
; Suárez-Morales, Eduardo
; Arruda, Eliane P. de
; Chiquito, Elisandra A.
; Lima, Élison F.B.
; Castro, Elizeu B. de
; Orlandin, Elton
; Nascimento, Elynton A. do
; Razzolini, Emanuel
; Gama, Emanuel R.R.
; Araujo, Enilma M. de
; Nishiyama, Eric Y.
; Spiessberger, Erich L.
; Santos, Érika C.L. dos
; Contreras, Eugenia F.
; Galati, Eunice A.B.
; Oliveira Junior, Evaldo C. de
; Gallardo, Fabiana
; Hernandes, Fabio A.
; Lansac-Tôha, Fábio A.
; Pitombo, Fabio B.
; Dario, Fabio Di
; Santos, Fábio L. dos
; Mauro, Fabio
; Nascimento, Fabio O. do
; Olmos, Fabio
; Amaral, Fabio R.
; Schunck, Fabio
; Godoi, Fábio S. P. de
; Machado, Fabrizio M.
; Barbo, Fausto E.
; Agrain, Federico A.
; Ribeiro, Felipe B.
; Moreira, Felipe F.F.
; Barbosa, Felipe F.
; Silva, Fenanda S.
; Cavalcanti, Fernanda F.
; Straube, Fernando C.
; Carbayo, Fernando
; Carvalho Filho, Fernando
; Zanella, Fernando C.V.
; Jacinavicius, Fernando de C.
; Farache, Fernando H.A.
; Leivas, Fernando
; Dias, Fernando M.S.
; Mantellato, Fernando
; Vaz-de-Mello, Fernando Z.
; Gudin, Filipe M.
; Albuquerque, Flávio
; Molina, Flavio B.
; Passos, Flávio D.
; Shockley, Floyd W.
; Pinheiro, Francielly F.
; Mello, Francisco de A.G. de
; Nascimento, Francisco E. de L.
; Franco, Francisco L.
; Oliveira, Francisco L. de
; Melo, Francisco T. de V.
; Quijano, Freddy R.B.
; Salles, Frederico F.
; Biffi, Gabriel
; Queiroz, Gabriel C.
; Bizarro, Gabriel L.
; Hrycyna, Gabriela
; Leviski, Gabriela
; Powell, Gareth S.
; Santos, Geane B. dos
; Morse, Geoffrey E.
; Brown, George
; Mattox, George M.T.
; Zimbrão, Geraldo
; Carvalho, Gervásio S.
; Miranda, Gil F.G.
; Moraes, Gilberto J. de
; Lourido, Gilcélia M.
; Neves, Gilmar P.
; Moreira, Gilson R.P.
; Montingelli, Giovanna G.
; Maurício, Giovanni N.
; Marconato, Gláucia
; Lopez, Guilherme E.L.
; Silva, Guilherme L. da
; Muricy, Guilherme
; Brito, Guilherme R.R.
; Garbino, Guilherme S.T.
; Flores, Gustavo E.
; Graciolli, Gustavo
; Libardi, Gustavo S.
; Proctor, Heather C.
; Gil-Santana, Helcio R.
; Varella, Henrique R.
; Escalona, Hermes E.
; Schmitz, Hermes J.
; Rodrigues, Higor D.D.
; Galvão Filho, Hilton de C.
; Quintino, Hingrid Y.S.
; Pinto, Hudson A.
; Rainho, Hugo L.
; Miyahira, Igor C.
; Gonçalves, Igor de S.
; Martins, Inês X.
; Cardoso, Irene A.
; Oliveira, Ismael B. de
; Franz, Ismael
; Fernandes, Itanna O.
; Golfetti, Ivan F.
; S. Campos-Filho, Ivanklin
; Oliveira, Ivo de S.
; Delabie, Jacques H.C.
; Oliveira, Jader de
; Prando, Jadila S.
; Patton, James L.
; Bitencourt, Jamille de A.
; Silva, Janaina M.
; Santos, Jandir C.
; Arruda, Janine O.
; Valderrama, Jefferson S.
; Dalapicolla, Jeronymo
; Oliveira, Jéssica P.
; Hájek, Jiri
; Morselli, João P.
; Narita, João P.
; Martin, João P.I.
; Grazia, Jocélia
; McHugh, Joe
; Cherem, Jorge J.
; Farias Júnior, José A.S.
; Fernandes, Jose A.M.
; Pacheco, José F.
; Birindelli, José L.O.
; Rezende, José M.
; Avendaño, Jose M.
; Duarte, José M. Barbanti
; Ribeiro, José R. Inácio
; Mermudes, José R.M.
; Pujol-Luz, José R.
; Santos, Josenilson R. dos
; Câmara, Josenir T.
; Teixeira, Joyce A.
; Prado, Joyce R. do
; Botero, Juan P.
; Almeida, Julia C.
; Kohler, Julia
; Gonçalves, Julia P.
; Beneti, Julia S.
; Donahue, Julian P.
; Alvim, Juliana
; Almeida, Juliana C.
; Segadilha, Juliana L.
; Wingert, Juliana M.
; Barbosa, Julianna F.
; Ferrer, Juliano
; Santos, Juliano F. dos
; Kuabara, Kamila M.D.
; Nascimento, Karine B.
; Schoeninger, Karine
; Campião, Karla M.
; Soares, Karla
; Zilch, Kássia
; Barão, Kim R.
; Teixeira, Larissa
; Sousa, Laura D. do N.M. de
; Dumas, Leandro L.
; Vieira, Leandro M.
; Azevedo, Leonardo H.G.
; Carvalho, Leonardo S.
; Souza, Leonardo S. de
; Rocha, Leonardo S.G.
; Bernardi, Leopoldo F.O.
; Vieira, Letícia M.
; Johann, Liana
; Salvatierra, Lidianne
; Oliveira, Livia de M.
; Loureiro, Lourdes M.A. El-moor
; Barreto, Luana B.
; Barros, Luana M.
; Lecci, Lucas
; Camargos, Lucas M. de
; Lima, Lucas R.C.
; Almeida, Lucia M.
; Martins, Luciana R.
; Marinoni, Luciane
; Moura, Luciano de A.
; Lima, Luciano
; Naka, Luciano N.
; Miranda, Lucília S.
; Salik, Lucy M.
; Bezerra, Luis E.A.
; Silveira, Luis F.
; Campos, Luiz A.
; Castro, Luiz A.S. de
; Pinho, Luiz C.
; Silveira, Luiz F.L.
; Iniesta, Luiz F.M.
; Tencatt, Luiz F.C.
; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
; Araújo, Marcel S. de
; Monné, Marcela L.
; Labruna, Marcelo B.
; Santis, Marcelo D. de
; Duarte, Marcelo
; Knoff, Marcelo
; Nogueira, Marcelo
; Britto, Marcelo R. de
; Melo, Marcelo R.S. de
; Carvalho, Marcelo R. de
; Tavares, Marcelo T.
; Kitahara, Marcelo V.
; Justo, Marcia C.N.
; Botelho, Marcia J.C.
; Couri, Márcia S.
; Borges-Martins, Márcio
; Felix, Márcio
; Oliveira, Marcio L. de
; Bologna, Marco A.
; Gottschalk, Marco S.
; Tavares, Marcos D.S.
; Lhano, Marcos G.
; Bevilaqua, Marcus
; Santos, Marcus T.T.
; Domingues, Marcus V.
; Sallum, Maria A.M.
; Digiani, María C.
; Santarém, Maria C.A.
; Nascimento, Maria C. do
; Becerril, María de los A.M.
; Santos, Maria E.A. dos
; Passos, Maria I. da S. dos
; Felippe-Bauer, Maria L.
; Cherman, Mariana A.
; Terossi, Mariana
; Bartz, Marie L.C.
; Barbosa, Marina F. de C.
; Loeb, Marina V.
; Cohn-Haft, Mario
; Cupello, Mario
; Martins, Marlúcia B.
; Christofersen, Martin L.
; Bento, Matheus
; Rocha, Matheus dos S.
; Martins, Maurício L.
; Segura, Melissa O.
; Cardenas, Melissa Q.
; Duarte, Mércia E.
; Ivie, Michael A.
; Mincarone, Michael M.
; Borges, Michela
; Monné, Miguel A.
; Casagrande, Mirna M.
; Fernandez, Monica A.
; Piovesan, Mônica
; Menezes, Naércio A.
; Benaim, Natalia P.
; Reategui, Natália S.
; Pedro, Natan C.
; Pecly, Nathalia H.
; Ferreira Júnior, Nelson
; Silva Júnior, Nelson J. da
; Perioto, Nelson W.
; Hamada, Neusa
; Degallier, Nicolas
; Chao, Ning L.
; Ferla, Noeli J.
; Mielke, Olaf H.H.
; Evangelista, Olivia
; Shibatta, Oscar A.
; Oliveira, Otto M.P.
; Albornoz, Pablo C.L.
; Dellapé, Pablo M.
; Gonçalves, Pablo R.
; Shimabukuro, Paloma H.F.
; Grossi, Paschoal
; Rodrigues, Patrícia E. da S.
; Lima, Patricia O.V.
; Velazco, Paul
; Santos, Paula B. dos
; Araújo, Paula B.
; Silva, Paula K.R.
; Riccardi, Paula R.
; Garcia, Paulo C. de A.
; Passos, Paulo G.H.
; Corgosinho, Paulo H.C.
; Lucinda, Paulo
; Costa, Paulo M.S.
; Alves, Paulo P.
; Roth, Paulo R. de O.
; Coelho, Paulo R.S.
; Duarte, Paulo R.M.
; Carvalho, Pedro F. de
; Gnaspini, Pedro
; Souza-Dias, Pedro G.B.
; Linardi, Pedro M.
; Bartholomay, Pedro R.
; Demite, Peterson R.
; Bulirsch, Petr
; Boll, Piter K.
; Pereira, Rachel M.M.
; Silva, Rafael A.P.F.
; Moura, Rafael B. de
; Boldrini, Rafael
; Silva, Rafaela A. da
; Falaschi, Rafaela L.
; Cordeiro, Ralf T.S.
; Mello, Ramon J.C.L.
; Singer, Randal A.
; Querino, Ranyse B.
; Heleodoro, Raphael A.
; Castilho, Raphael de C.
; Constantino, Reginaldo
; Guedes, Reinaldo C.
; Carrenho, Renan
; Gomes, Renata S.
; Gregorin, Renato
; Machado, Renato J.P.
; Bérnils, Renato S.
; Capellari, Renato S.
; Silva, Ricardo B.
; Kawada, Ricardo
; Dias, Ricardo M.
; Siewert, Ricardo
; Brugnera, Ricaro
; Leschen, Richard A.B.
; Constantin, Robert
; Robbins, Robert
; Pinto, Roberta R.
; Reis, Roberto E. dos
; Ramos, Robson T. da C.
; Cavichioli, Rodney R.
; Barros, Rodolfo C. de
; Caires, Rodrigo A.
; Salvador, Rodrigo B.
; Marques, Rodrigo C.
; Araújo, Rodrigo C.
; Araujo, Rodrigo de O.
; Dios, Rodrigo de V.P.
; Johnsson, Rodrigo
; Feitosa, Rodrigo M.
; Hutchings, Roger W.
; Lara, Rogéria I.R.
; Rossi, Rogério V.
; Gerstmeier, Roland
; Ochoa, Ronald
; Hutchings, Rosa S.G.
; Ale-Rocha, Rosaly
; Rocha, Rosana M. da
; Tidon, Rosana
; Brito, Rosangela
; Pellens, Roseli
; Santos, Sabrina R. dos
; Santos, Sandra D. dos
; Paiva, Sandra V.
; Santos, Sandro
; Oliveira, Sarah S. de
; Costa, Sávio C.
; Gardner, Scott L.
; Leal, Sebastián A. Muñoz
; Aloquio, Sergio
; Bonecker, Sergio L.C.
; Bueno, Sergio L. de S.
; Almeida, Sérgio M. de
; Stampar, Sérgio N.
; Andena, Sérgio R.
; Posso, Sergio R.
; Lima, Sheila P.
; Gadelha, Sian de S.
; Thiengo, Silvana C.
; Cohen, Simone C.
; Brandão, Simone N.
; Rosa, Simone P.
; Ribeiro, Síria L.B.
; Letana, Sócrates D.
; Santos, Sonia B. dos
; Andrade, Sonia C.S.
; Dávila, Stephane
; Vaz, Stéphanie
; Peck, Stewart B.
; Christo, Susete W.
; Cunha, Suzan B.Z.
; Gomes, Suzete R.
; Duarte, Tácio
; Madeira-Ott, Taís
; Marques, Taísa
; Roell, Talita
; Lima, Tarcilla C. de
; Sepulveda, Tatiana A.
; Maria, Tatiana F.
; Ruschel, Tatiana P.
; Rodrigues, Thaiana
; Marinho, Thais A.
; Almeida, Thaís M. de
; Miranda, Thaís P.
; Freitas, Thales R.O.
; Pereira, Thalles P.L.
; Zacca, Thamara
; Pacheco, Thaynara L.
; Martins, Thiago F.
; Alvarenga, Thiago M.
; Carvalho, Thiago R. de
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Henry, Thomas
; Pikart, Tiago G.
; Porto, Tiago J.
; Krolow, Tiago K.
; Carvalho, Tiago P.
; Lotufo, Tito M. da C.
; Caramaschi, Ulisses
; Pinheiro, Ulisses dos S.
; Pardiñas, Ulyses F.J.
; Maia, Valéria C.
; Tavares, Valeria
; Costa, Valmir A.
; Amaral, Vanessa S. do
; Silva, Vera C.
; Wolff, Vera R. dos S.
; Slobodian, Verônica
; Silva, Vinícius B. da
; Espíndola, Vinicius C.
; Costa-Silva, Vinicius da
; Bertaco, Vinicius de A.
; Padula, Vinícius
; Ferreira, Vinicius S.
; Silva, Vitor C.P. da
; Piacentini, Vítor de Q.
; Sandoval-Gómez, Vivian E.
; Trevine, Vivian
; Sousa, Viviane R.
; Sant’Anna, Vivianne B. de
; Mathis, Wayne N.
; Souza, Wesley de O.
; Colombo, Wesley D.
; Tomaszewska, Wioletta
; Wosiacki, Wolmar B.
; Ovando, Ximena M.C.
; Leite, Yuri L.R.
.
ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
6.
Producción del territorio y del hábitat rural: tensiones y disputas en el Sur global
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7.
Geospatialization of tuberculosis and income transfer programs among Indigenous peoples in an endemic territory
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Lima, Ingrid Bentes
; Nogueira, Laura Maria Vidal
; Trindade, Lidiane de Nazaré Mota
; Rodrigues, Ivaneide Leal Ataide
; André, Suzana Rosa
; Sousa, Ana Inês
.
RESUMO Objetivo: Analisar o padrão espacial de tuberculose em indígenas do Pará e sua correlação com transferência de renda. Métodos: Estudo ecológico, com 340 casos notificados em indígenas no Pará/Brasil, no período 2016-2020. Realizou-se análise descritiva e cálculo das taxas de incidência com suavização pelo método bayesiano empírico local. Fez-se autocorrelação das taxas com dados de transferência de renda pelo Moran Global, p<0,05. Resultados: As mesorregiões Marajó e Metropolitana de Belém apresentaram as taxas de tuberculose mais elevadas e reduzido número de pessoas beneficiadas com transferência de renda (correlação alto-baixo). No Sudoeste, identificaram se taxas elevadas e número significativo de pessoas beneficiadas com os auxílios financeiros (correlação alto alto), I=0,399, p=0,027. Conclusões: A autocorrelação espacial entre tuberculose e acesso a programas de transferência de renda constitui importante subsídio para formulação de políticas de proteção social, podendo impactar as ações de controle da doença nos territórios indígenas, valorizando a heterogeneidade epidemiológica identificada nas mesorregiões.
ABSTRACT Objective: To analyze the spatial pattern of tuberculosis in Indigenous peoples from the State of Pará and its correlation with income transfer. Methods: Ecological study, with 340 cases reported in Indigenous peoples in the State of Pará, Brazil, in the period 2016-2020. The study performed a descriptive analysis and calculation of incidence rates with smoothing by the local empirical Bayesian method. The Global Moran index assessed the autocorrelation of the rates with income transfer data, p<0,05. Results: The Marajó and metropolitan mesoregions of Belém had the highest tuberculosis rates, and a reduced number of people benefited from income transfer (high-low correlation). The study identified high rates, and a significant number of people benefited from financial aid (high correlation high), I=0.399, p=0.027 in the Southwest. Conclusions: The spatial autocorrelation between tuberculosis and access to income transfer programs constitutes a relevant subsidy for the formulation of social protection policies and may impact the disease control actions in Indigenous territories, valuing the epidemiological heterogeneity identified in the mesoregions.
RESUMEN Objetivo: Analizar patrón espacial de tuberculosis en indígenas de Pará y su correlación con transferencia de renta. Métodos: Estudio ecológico, con 340 casos notificados en indígenas en Pará/Brasil, entre 2016-2020. Realizado análisis descriptivo y cálculo de tasas de incidencia con moderación por el método bayesiano empírico local. Hecho autocorrelación de tasas con datos de transferencia de renta por Moran Global, p<0,05. Resultados: Las mesorregiones Marajó y Metropolitana de Belém presentaron las tasas de tuberculosis mayores y reducido número de personas beneficiadas con transferencia de renta (correlación alto-bajo). En el Sudoeste, identificaron tasas elevadas y número significativo de personas beneficiadas con auxilios financieros (correlación alto-alto), I=0,399, p=0,027. Conclusiones: La autocorrelación espacial entre tuberculosis y acceso a programas de transferencia de renta constituye importante subsidio para formulación de políticas de protección social, pudiendo impactar las acciones de control de la enfermedad en territorios indígenas, valorizando la heterogeneidad epidemiológica identificada en las mesorregiones.
8.
Baby-Friendly Hospital Initiative and exclusive breastfeeding during hospital stay BabyFriendly Baby Friendly
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von Seehausen, Mariana Pujól
; Oliveira, Maria Inês Couto de
; Leal, Maria do Carmo
; Domingues, Rosa Maria Soares Madeira
; Boccolini, Cristiano Siqueira
.
ABSTRACT OBJECTIVE To estimate the prevalence of exclusive breastfeeding during maternity hospital stay (outcome) and to analyze the association between delivery in a Baby-Friendly Hospital (BFH) and the outcome. The hypothesis is that accreditation to this program improves exclusive breastfeeding during maternity hospital stay. Exclusive breastfeeding is essential in reducing neonatal morbidity and mortality. METHODS This study is based on secondary data collected by the “Birth in Brazil: National Survey into Labour and Birth”, a population-based study, conducted with 21,086 postpartum women, from February 1, 2011, to October 31, 2012, in 266 hospitals from all five Brazilian regions. Face-to-face interviews were conducted mostly within the first 24 hours after birth, regarding individual and gestational characteristics, prenatal care, delivery, newborn’s characteristics, and breastfeeding at birth. A theoretical model was created, allocating the exposure variables in three levels based on their proximity to the outcome. This hierarchical conceptual model was applied to perform a multiple logistic regression (with 95%CI and p < 0.05). RESULTS In this study, 76.0% of the babies were exclusively breastfed from birth until the interview. Babies born in public (AOR = 1.73; 95%CI: 1.10–2.87), mixed (AOR = 2.48; 95%CI: 1.35–4.53) and private (AOR = 5.54; 95%CI: 2.38–12.45) BFHs were more likely to be exclusively breastfed during maternity hospital stay than those born in non–BFHs, as well as those born by vaginal birth (AOR = 2.16; 95%CI: 1.79–2.61), with adolescent mothers (AOR = 1.83; 95%CI: 1.47–2.26) or adults up to 34 years old (AOR =1 .31; 95%CI: 1.13–1.52), primiparous women (AOR = 1.51; 95%CI: 1.34–1.70), and mothers living in the Northern region of Brazil (AOR = 1.99; 95%CI: 1.14–3.49). CONCLUSIONS The Baby-Friendly Hospital Initiative promotes exclusive breastfeeding during hospital stay regarding individual and hospital differences. outcome (outcome BabyFriendly Baby Friendly BFH (BFH mortality Birth Birth, , Birth” populationbased population 21086 21 086 21,08 1 2011 31 2012 26 regions Facetoface Face face 2 characteristics care newborns newborn s created 95CI CI 95 0.05. 005 0.05 . 0 05 0.05) 760 76 76.0 interview AOR 1.73 173 73 1.10–2.87, 110287 1.10–2.87 10 87 1.10–2.87) 2.48 248 48 1.35–4.53 135453 35 4 53 5.54 554 5 54 2.38–12.45 2381245 38 12 45 nonBFHs non non–BFHs 2.16 216 16 1.79–2.61, 179261 1.79–2.61 79 61 1.79–2.61) 1.83 183 83 1.47–2.26 147226 47 3 .31 1.13–1.52, 113152 1.13–1.52 13 52 1.13–1.52) 1.51 151 51 1.34–1.70, 134170 1.34–1.70 70 1.34–1.70) 1.99 199 99 1.14–3.49. 114349 1.14–3.49 14 49 1.14–3.49) differences 2108 08 21,0 201 9 00 0.0 7 76. 1.7 17 11028 1.10–2.8 8 2.4 1.35–4.5 13545 5.5 55 2.38–12.4 238124 2.1 17926 1.79–2.6 6 1.8 18 1.47–2.2 14722 .3 11315 1.13–1.5 1.5 15 13417 1.34–1.7 1.9 19 11434 1.14–3.4 210 21, 20 0. 1. 1102 1.10–2. 2. 1.35–4. 1354 5. 2.38–12. 23812 1792 1.79–2. 1.47–2. 1472 1131 1.13–1. 1341 1.34–1. 1143 1.14–3. 110 1.10–2 1.35–4 135 2.38–12 2381 179 1.79–2 1.47–2 147 113 1.13–1 134 1.34–1 114 1.14–3 11 1.10– 1.35– 2.38–1 238 1.79– 1.47– 1.13– 1.34– 1.14– 1.10 1.35 2.38– 23 1.79 1.47 1.13 1.34 1.14 1.1 1.3 2.38 1.4 2.3
9.
Biomarkers of neuropsychiatric dysfunction in intensive care unit survivors: a prospective cohort study survivors
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Rocha, Franciani Rodrigues da
; Gonçalves, Renata Casagrande
; Prestes, Gabriele da Silveira
; Damásio, Danusa
; Goulart, Amanda Indalécio
; Vieira, Andriele Aparecida da Silva
; Michels, Monique
; Rosa, Maria Inês da
; Ritter, Cristiane
; Dal-Pizzol, Felipe
.
RESUMO Objetivo: Avaliar os fatores associados aos desfechos neuropsiquiátricos de longo prazo, incluindo biomarcadores, medidos após a alta da unidade de terapia intensiva. Métodos: Foi realizado um estudo de coorte prospectivo com 65 sobreviventes de unidades de terapia intensiva. A avaliação cognitiva foi realizada por meio do Miniexame do Estado Mental; os sintomas de ansiedade e depressão foram avaliados por meio da Escala Hospitalar de Ansiedade e Depressão, e o transtorno de estresse pós-traumático foi avaliado pela Escala de Impacto do Evento-6. Os níveis plasmáticos de beta amiloide (1-42), beta amiloide (1-40), interleucina 10, interleucina 6, interleucina 33, interleucina 4, interleucina 5, fator de necrose tumoral alfa, proteína C-reativa e fator neurotrófico derivado do cérebro foram medidos na alta da unidade de terapia intensiva. Resultados: Das variáveis associadas à terapia intensiva, apenas o delirium foi relacionado de forma independente à ocorrência de comprometimento cognitivo de longo prazo. Além disso, níveis mais altos de interleucina 10 e interleucina 6 foram associados à disfunção cognitiva. Apenas a interleucina 6 foi associada de forma independente à depressão. A ventilação mecânica, os níveis de interleucina 33 e os níveis de proteína C-reativa foram associados de forma independente à ansiedade. Nenhuma variável foi associada de forma independente ao transtorno de estresse pós-traumático. Conclusão: A disfunção cognitiva, bem como os sintomas de depressão, ansiedade e transtorno de estresse pós-traumático, estão presentes em pacientes que sobrevivem a uma doença grave, e alguns desses desfechos estão associados aos níveis de biomarcadores inflamatórios medidos na alta da unidade de terapia intensiva. Objetivo prazo intensiva Métodos Mental Depressão póstraumático pós traumático Evento6. Evento6 Evento 6. Evento-6 142, 142 1 42 , (1-42) 140, 140 40 (1-40) 4 5 alfa Creativa C reativa Resultados disso mecânica 3 póstraumático. traumático. Conclusão póstraumático, traumático, grave Evento- 14 (1-42 (1-40 (1-4 (1- (1 (
ABSTRACT Objective: To assess factors associated with long-term neuropsychiatric outcomes, including biomarkers measured after discharge from the intensive care unit. Methods: A prospective cohort study was performed with 65 intensive care unit survivors. The cognitive evaluation was performed through the Mini-Mental State Examination, the symptoms of anxiety and depression were evaluated using the Hospital Anxiety and Depression Scale, and posttraumatic stress disorder was evaluated using the Impact of Event Scale-6. Plasma levels of amyloid-beta (1-42) [Aβ (1-42)], Aβ (1-40), interleukin (IL)-10, IL-6, IL-33, IL-4, IL-5, tumor necrosis factor alpha, C-reactive protein, and brain-derived neurotrophic factor were measured at intensive care unit discharge. Results: Of the variables associated with intensive care, only delirium was independently related to the occurrence of long-term cognitive impairment. In addition, higher levels of IL-10 and IL-6 were associated with cognitive dysfunction. Only IL-6 was independently associated with depression. Mechanical ventilation, IL-33 levels, and C-reactive protein levels were independently associated with anxiety. No variables were independently associated with posttraumatic stress disorder. Conclusion: Cognitive dysfunction, as well as symptoms of depression, anxiety, and posttraumatic stress disorder, are present in patients who survive a critical illness, and some of these outcomes are associated with the levels of inflammatory biomarkers measured at discharge from the intensive care unit. Objective longterm long term Methods 6 survivors MiniMental Mini Mental Examination Scale Scale6. Scale6 6. Scale-6 amyloidbeta amyloid beta 142 1 42 (1-42 142, , (1-42)] 140, 140 40 (1-40) IL10, IL10 IL 10, 10 (IL)-10 IL6, IL6 6, IL33, IL33 33, 33 IL4, IL4 4, 4 IL-4 IL5, IL5 5, 5 IL-5 alpha Creactive C reactive brainderived brain derived Results impairment addition IL-1 IL- dysfunction ventilation IL-3 Conclusion illness Scale- 14 (1-4 (1-40 IL1 (IL)-1 IL3 3 (1- (IL)- (1 (IL) ( (IL
10.
Epidemiological profile of congenital hypothyroidism at a southern Brazilian state
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Boff, Márcia Inês
; Kopacek, Cristiane
; Souza, Vandrea Carla de
; Ribeiro, Sabliny Carreiro
; Kreisner, Edmundo
; Vargas, Paula Regla
; Mastella, Livia Silveira
; Madi, José Mauro
; Castro, Simone Martins de
; Rahmi, Rosa Maria
.
ABSTRACT Objective: To determine the incidence of congenital hypothyroidism (CH) over a 10-year period at the Reference Service in Neonatal Screening of the state of Rio Grande do Sul (RSNS-RS). Subjects and methods: Historical cohort study including all newborns screened for CH by the RSNS-RS from January 2008 until December 2017. Data of all newborns with neonatal TSH (neoTSH; heel prick test) values ≥ 9 mIU/L were collected. According to neoTSH values, the newborns were allocated into two groups: Group 1 (G1), comprising newborns with neoTSH ≥ 9 mIU/L and serum TSH (sTSH) < 10 mIU/L, and Group 2 (G2), comprising those with neoTSH ≥ 9 mIU/L and sTSH ≥ 10 mIU/L. Results: Of 1,043,565 newborns screened, 829 (0.08%) had neoTSH values ≥ 9 mIU/L. Of these, 284 (39.3%) had sTSH values < 10 mIU/L and were allocated to the G1 group, while 439 (60.7%) had sTSH ≥ 10 mIU/L and were allocated to the G2 group, and 106 (12.7%) were considered missing data. The overall incidence of CH was 42.1 per 100,000 newborns screened (95% confidence interval [CI] 38.5-45.7/100,000) or 1:2377 screened newborns. The sensibility and specificity of neoTSH ≥ 9 mIU/L were 97% and 11%; of neoTSH 12.6 mUI/L, 73% and 85% respectively. Conclusion: In this population, the incidence of permanent and transitory CH was 1:2377 screened newborns. The neoTSH cutoff value adopted during the study period showed excellent sensibility, which matters for a screening test. Objective (CH 10year year RSNSRS. RSNSRS RSNS RS . (RSNS-RS) methods 200 2017 (neoTSH test mIUL mIU L collected groups G1, G , (G1) (sTSH G2, (G2) Results 1043565 043 565 1,043,56 82 0.08% 008 0 08 (0.08% these 28 39.3% 393 39 3 (39.3% group 43 60.7% 607 60 7 (60.7% 12.7% 127 12 (12.7% data 421 42 42. 100000 100 000 100,00 95% 95 (95 CI [CI 38.545.7/100,000 385457100000 38.5 45.7/100,000 38 5 45 38.5-45.7/100,000 12377 2377 1:237 97 11% 11 126 6 12. mUIL mUI mUI/L 73 85 respectively Conclusion population (RSNS-RS 20 201 (G1 (G2 104356 04 56 1,043,5 8 0.08 00 (0.08 39.3 (39.3 4 60.7 (60.7 12.7 (12.7 10000 100,0 (9 545 38.545.7/100,00 38545710000 385 38. 457100000 45.7/100,00 38.5-45.7/100,00 1237 237 1:23 (G 10435 1,043, 0.0 (0.0 39. (39. 60. (60. (12. 1000 100, ( 54 38.545.7/100,0 3854571000 45710000 45.7/100,0 38.5-45.7/100,0 123 23 1:2 1043 1,043 0. (0. (39 (60 (12 38.545.7/100, 385457100 4571000 45.7/100, 38.5-45.7/100, 1: 104 1,04 (0 (3 (6 (1 38.545.7/100 38545710 457100 45.7/100 38.5-45.7/100 1,0 38.545.7/10 3854571 45710 45.7/10 38.5-45.7/10 1, 38.545.7/1 385457 4571 45.7/1 38.5-45.7/1 38.545.7/ 38545 457 45.7/ 38.5-45.7/ 38.545.7 3854 45.7 38.5-45.7 38.545. 45. 38.5-45. 38.545 38.5-45 38.54 38.5-4 38.5-
11.
MOTHERHOOD: CONFLICTS BETWEEN THE BIOLOGICAL AND THE SOCIAL DIMENSIONS - WHAT DOES THE BRAZILIAN ACADEMIC PRODUCTION TELL? MOTHERHOOD TELL
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Ensaio Pesquisa em Educação em Ciências (Belo Horizonte)
- Journal Metrics
RESUMEN: Esta revisión bibliográfica presenta un conjunto de investigaciones sobre la maternidad como una práctica social construida, el discurso determinista de la biología y cómo emerge en la formación de los biólogos y profesores. El foco son las producciones académicas brasileñas sobre este tema y los aspectos relacionados. En relación con el enfoque metodológico, se recolectaron los artículos en el Portal CAPES en búsquedas dirigidas por descriptores previamente definidos. Se encontró un conjunto de veintitrés artículos y su análisis resultó en tres categorías temáticas: 1. ¿Qué es una madre?; 2. Amamantamiento; 3. ¿Qué es una mujer? - el discurso biológico en escena. Los resultados demuestran la escasa discusión sobre temas específicos. Por lo general, los discursos que hablan directamente sobre las características biológicas en las mujeres confirman el lugar social que les atribuye la sociedad, a lo largo del tiempo, dieron paso a otros discursos sexitas, sin embargo ocultados por la neutralidad científica. En la producción del conocimiento científico, se evidencia el propósito de justificar los estereotipos en los modos de los cuerpos femenino y masculino y, consecuentemente, las desigualdades. RESUMEN construida profesores relacionados metodológico definidos temáticas 1 Qué madre madre? 2 Amamantamiento 3 mujer escena específicos general sociedad tiempo sexitas científica científico consecuentemente desigualdades
RESUMO: Esta revisão bibliográfica apresenta um conjunto de pesquisas sobre a maternidade como prática social construída, o discurso determinista da biologia e como emerge na formação de biólogos e professores. O foco está nas produções acadêmicas brasileiras sobre esse tema e seus aspectos relacionados. Quanto à abordagem metodológica, os artigos foram levantados do Portal CAPES em buscas direcionadas por descritores previamente definidos. Foi encontrado um conjunto de 23 artigos e sua análise resultou em 3 categorias temáticas: 1. O que é mãe?; 2. Amamentação; 3. O que é uma mulher? - o discurso biológico em cena. Os resultados demonstram a escassa discussão sobre temas específicos. Em linhas gerais, os discursos que falam diretamente sobre as características biológicas nas mulheres corroboram com o lugar social que lhes é destinado, ao longo do tempo, deram lugar a outros discursos sexistas, porém, mascarados sob a neutralidade científica. Na produção do conhecimento científico, fica evidente o propósito de justificar os estereótipos nos modos dos corpos feminino e masculino e, consequentemente, as desigualdades. RESUMO construída professores relacionados metodológica definidos 2 temáticas 1 mãe mãe? Amamentação mulher cena específicos gerais destinado tempo sexistas porém científica científico consequentemente desigualdades
ABSTRACT: This bibliographical review presents a set of research about motherhood as a constructed social practice, the deterministic discourse of biology, and how it emerges in the training of biologists and teachers. The focus is on the Brazilian academic productions about this subject and its related aspects. About the methodological approach, the papers were raised from CAPES Portal in searches directed by descriptors previously defined. A set of 23 papers were found, and their analysis resulted in 3 thematic categories: 1. What is a mother?; 2. Breastfeeding; 3. What is a woman? - the biological discourse on stage. The results demonstrate the scarce discussion on specific topics. In general terms, discourses that speak directly about biological characteristics in women corroborate with the social place intended for them, over time, gave way to other sexist discourses, however masking under scientific neutrality. Within the production of scientific knowledge, it is evident that the purpose is to justify stereotypes in female and male bodies ways and, consequently, inequalities. ABSTRACT practice biology teachers aspects approach defined 2 found categories 1 mother mother? Breastfeeding woman stage topics terms them time neutrality knowledge consequently inequalities
12.
Baby-Friendly Hospital Initiative and exclusive breastfeeding during hospital stay
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von Seehausen, Mariana Pujól
; Oliveira, Maria Inês Couto de
; Leal, Maria do Carmo
; Domingues, Rosa Maria Soares Madeira
; Boccolini, Cristiano Siqueira
.
ABSTRACT OBJECTIVE To estimate the prevalence of exclusive breastfeeding during maternity hospital stay (outcome) and to analyze the association between delivery in a Baby-Friendly Hospital (BFH) and the outcome. The hypothesis is that accreditation to this program improves exclusive breastfeeding during maternity hospital stay. Exclusive breastfeeding is essential in reducing neonatal morbidity and mortality. METHODS This study is based on secondary data collected by the “Birth in Brazil: National Survey into Labour and Birth”, a population-based study, conducted with 21,086 postpartum women, from February 1, 2011, to October 31, 2012, in 266 hospitals from all five Brazilian regions. Face-to-face interviews were conducted mostly within the first 24 hours after birth, regarding individual and gestational characteristics, prenatal care, delivery, newborn’s characteristics, and breastfeeding at birth. A theoretical model was created, allocating the exposure variables in three levels based on their proximity to the outcome. This hierarchical conceptual model was applied to perform a multiple logistic regression (with 95%CI and p < 0.05). RESULTS In this study, 76.0% of the babies were exclusively breastfed from birth until the interview. Babies born in public (AOR = 1.73; 95%CI: 1.10–2.87), mixed (AOR = 2.48; 95%CI: 1.35–4.53) and private (AOR = 5.54; 95%CI: 2.38–12.45) BFHs were more likely to be exclusively breastfed during maternity hospital stay than those born in non–BFHs, as well as those born by vaginal birth (AOR = 2.16; 95%CI: 1.79–2.61), with adolescent mothers (AOR = 1.83; 95%CI: 1.47–2.26) or adults up to 34 years old (AOR =1 .31; 95%CI: 1.13–1.52), primiparous women (AOR = 1.51; 95%CI: 1.34–1.70), and mothers living in the Northern region of Brazil (AOR = 1.99; 95%CI: 1.14–3.49). CONCLUSIONS The Baby-Friendly Hospital Initiative promotes exclusive breastfeeding during hospital stay regarding individual and hospital differences.
13.
O que mudou entre os períodos de pico e de platô durante a primeira onda do SARS-CoV-2? Estudo multicêntrico português em unidades de cuidados intensivos SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV-2 SARS-CoV- SARS-CoV
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Pereira, Rui Antunes
; Sousa, Marta
; Cidade, José Pedro
; Melo, Luís
; Lopes, Diogo
; Ventura, Sara
; Aragão, Irene
; Lima Neto, Raul Miguel de Freitas
; Molinos, Elena
; Marques, Ana
; Cardoso, Nelson
; Marino, Flávio
; Monteiro, Filipa Brás
; Oliveira, Ana Pinho
; Silva, Rogério C
; Real, André Miguel Neto
; Banheiro, Bruno Sarmento
; Reis, Renato
; Adão-Serrano, Maria
; Cracium, Ana
; Valadas, Ana
; Ribeiro, João Miguel
; Póvoa, Pedro
; Tapadinhas, Camila
; Mendes, Vítor
; Coelho, Luís
; Maia, Raquel
; Freitas, Paulo Telles
; Ferreira, Isabel Amorim
; Ramires, Tiago
; Val-Flores, Luís Silva
; Cascão, Mariana
; Alves, Rita
; Rodeia, Simão C
; Barrigoto, Cleide
; Cardiga, Rosa
; Silva, Maria João Ferreira da
; Vale, Bruno
; Fonseca, Tatiana
; Rios, Ana Lúcia
; Camões, João
; Pérez, Danay
; Cabral, Susana
; Ribeiro, Maria Inês
; Mendes, João João
; Gouveia, João
; Fernandes, Susana Mendes
.
RESUMO Objetivo: Analisar e comparar as características de pacientes críticos com a COVID-19, a abordagem clínica e os resultados entre os períodos de pico e de platô na primeira onda pandêmica em Portugal. Métodos: Este foi um estudo de coorte multicêntrico ambispectivo, que incluiu pacientes consecutivos com a forma grave da COVID-19 entre março e agosto de 2020 de 16 unidades de terapia intensiva portuguesas. Definiram-se as semanas 10 - 16 e 17 - 34 como os períodos de pico e platô. Resultados: Incluíram-se 541 pacientes adultos com mediana de idade de 65 [57 - 74] anos, a maioria do sexo masculino (71,2%). Não houve diferenças significativas na mediana de idade (p = 0,3), no Simplified Acute Physiology Score II (40 versus 39; p = 0,8), na pressão parcial de oxigênio/fração inspirada de oxigênio (139 versus 136; p = 0,6), na terapia com antibióticos na admissão (57% versus 64%; p = 0,2) ou na mortalidade aos 28 dias (24,4% versus 22,8%; p = 0,7) entre o período de pico e platô. Durante o período de pico, os pacientes tiveram menos comorbidades (1 [0 - 3] versus 2 [0 - 5]; p = 0,002); fizeram mais uso de vasopressores (47% versus 36%; p < 0,001) e ventilação mecânica invasiva na admissão (58,1% versus 49,2%; p < 0,001), e tiveram mais prescrição de hidroxicloroquina (59% versus 10%; p < 0,001), lopinavir/ritonavir (41% versus 10%; p < 0,001) e posição prona (45% versus 36%; p = 0,04). Entretanto, durante o platô, observou-se maior uso de cânulas nasais de alto fluxo (5% versus 16%; p < 0,001) na admissão, remdesivir (0,3% versus 15%; p < 0,001) e corticosteroides (29% versus 52%; p < 0,001), além de menor tempo de internação na unidade de terapia intensiva (12 versus 8 dias; p < 0,001). Conclusão: Houve mudanças significativas nas comorbidades dos pacientes, nos tratamentos da unidade de terapia intensiva e no tempo de internação entre os períodos de pico e platô na primeira onda da COVID-19. Objetivo COVID19, COVID19 COVID 19, 19 Portugal Métodos ambispectivo COVID-1 202 1 portuguesas Definiramse Definiram se 3 Resultados Incluíramse Incluíram 54 6 57 [5 74 anos 71,2%. 712 71,2% . 71 (71,2%) 0,3, 03 0,3 , 0 0,3) 40 (4 39 0,8, 08 0,8 0,8) oxigêniofração fração 139 (13 136 0,6, 06 0,6 0,6) 57% (57 64% 64 0,2 02 24,4% 244 24 4 (24,4 22,8% 228 22 0,7 07 7 ( [ 5 5] 0,002 0002 002 0,002) 47% 47 (47 36% 36 0,001 0001 001 58,1% 581 58 (58,1 49,2% 492 49 0,001, 59% 59 (59 10% lopinavirritonavir lopinavir ritonavir 41% 41 (41 45% 45 (45 0,04. 004 0,04 04 0,04) Entretanto observouse observou 5% (5 16% 0,3% (0,3 15% 15 29% 29 (29 52% 52 12 0,001. Conclusão COVID19. 19. COVID1 COVID- 20 71,2 (71,2% 0, 13 24,4 (24, 22,8 0,00 000 00 58,1 (58, 49,2 0,0 (0, (2 71, (71,2 24, (24 22, 58, (58 49, (0 (71, (71 (7
ABSTRACT Objective: To analyze and compare COVID-19 patient characteristics, clinical management and outcomes between the peak and plateau periods of the first pandemic wave in Portugal. Methods: This was a multicentric ambispective cohort study including consecutive severe COVID-19 patients between March and August 2020 from 16 Portuguese intensive care units. The peak and plateau periods, respectively, weeks 10 - 16 and 17 - 34, were defined. Results: Five hundred forty-one adult patients with a median age of 65 [57 - 74] years, mostly male (71.2%), were included. There were no significant differences in median age (p = 0.3), Simplified Acute Physiology Score II (40 versus 39; p = 0.8), partial arterial oxygen pressure/fraction of inspired oxygen ratio (139 versus 136; p = 0.6), antibiotic therapy (57% versus 64%; p = 0.2) at admission, or 28-day mortality (24.4% versus 22.8%; p = 0.7) between the peak and plateau periods. During the peak period, patients had fewer comorbidities (1 [0 - 3] versus 2 [0 - 5]; p = 0.002) and presented a higher use of vasopressors (47% versus 36%; p < 0.001) and invasive mechanical ventilation (58.1 versus 49.2%; p < 0.001) at admission, prone positioning (45% versus 36%; p = 0.04), and hydroxychloroquine (59% versus 10%; p < 0.001) and lopinavir/ritonavir (41% versus 10%; p < 0.001) prescriptions. However, a greater use of high-flow nasal cannulas (5% versus 16%, p < 0.001) on admission, remdesivir (0.3% versus 15%; p < 0.001) and corticosteroid (29% versus 52%, p < 0.001) therapy, and a shorter ICU length of stay (12 days versus 8, p < 0.001) were observed during the plateau. Conclusion: There were significant changes in patient comorbidities, intensive care unit therapies and length of stay between the peak and plateau periods of the first COVID-19 wave. Objective COVID19 COVID 19 COVID-1 characteristics Portugal Methods 202 1 units respectively 34 defined Results fortyone forty one 6 57 [5 74 years 71.2%, 712 71.2% , 71 (71.2%) included 0.3, 03 0.3 0 3 0.3) 40 (4 39 0.8, 08 0.8 8 0.8) pressurefraction pressure fraction 139 (13 136 0.6, 06 0.6 0.6) 57% (57 64% 64 0.2 02 admission 28day day 28 24.4% 244 24 4 (24.4 22.8% 228 22 0.7 07 7 period ( [ 5 5] 0.002 0002 002 47% 47 (47 36% 36 0.001 0001 001 58.1 581 58 (58. 49.2% 492 49 45% 45 (45 0.04, 004 0.04 04 0.04) 59% 59 (59 10% lopinavirritonavir lopinavir ritonavir 41% 41 (41 prescriptions However highflow high flow 5% (5 16% 0.3% (0.3 15% 15 29% 29 (29 52 52% 12 Conclusion COVID1 COVID- 20 71.2 (71.2% 0. 13 24.4 (24. 22.8 0.00 000 00 58. (58 49.2 0.0 (0. (2 71. (71.2 24. (24 22. 49. (0 (71. (71 (7
14.
Vitamin D supplementation during pregnancy to prevent vitamin D deficiency in newborns: a systematic review and meta-analysis
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Colonetti, Tamy
; Paulino, Amabile Scremin
; Sartor, Jaíne Paulina
; Grande, Antonio Jose
; Colonetti, Laura
; Rosa, Maria Inês da
.
Revista Brasileira de Saúde Materno Infantil
- Journal Metrics
Resumo Objetivos: avaliar os efeitos da suplementação materna de vitamina D durante a gravidez nos desfechos concentração de vitamina D no recém-nascido, comprimento ao nascer, estado geral de saúde (Apgar), peso ao nascer e concentração de vitamina D materna após o nascimento. Métodos: a pesquisa foi conduzida nas bases de dados eletrônicas MEDLINE, LILACS, EMBASE e Cochrane Library até dezembro de 2020, utilizando os termos “vitamin D”, “pregnancy”, “vitamin D deficiency”, “infant”, “newborn” e seus sinônimos. Pesquisou-se por ensaios clínicos randomizados avaliando os efeitos da suplementação materna de vitamina D no neonato. Os dados foram analisados pelo software RevMan 5.4 e a avaliação da qualidade das evidências pelo GRADE. Resultados: o estado geral de saúde do recém-nascido foi apresentado como Apgar, com uma diferença de média (DM) de 0,15 (IC95%=0,06-0,25; p=0,002; I2=0%, dois estudos, 648 participantes, evidência de qualidade moderada) para o teste no primeiro minuto e 0,11 (IC95%=0,04-0,17; p=0,001; I2=0%, dois estudos, 648 participantes, evidência de qualidade moderada) para quinto minuto. Efeitos significativos também foram apresentados para o comprimento ao nascer em qualquer dose suplementada (DM=0,19 (IC95%=0,08-0,30; p=0,0010; I2=0%, 1452 participantes, evidência de baixa qualidade) e peso ao nascer em doses maiores que 4000UI/dia (DM=257,05 (IC95%=137,81-376,29; p<0,0001; I2=14%, 176 participantes, evidência de qualidade moderada). Conclusão: a suplementação de vitamina D durante a gravidez melhora a concentração sérica de 25 (OH)D e sugere apresentar efeitos positivos no estado geral de saúde, comprimento ao nascer e peso ao nascer. PROSPERO CRD42017073292.
Abstract Objectives: to assess the effects of vitamin D supplementation during pregnancy on the outcomes of vitamin D concentration in newborns, length at birth, overall health (Apgar), birth weight and maternal vitamin D concentration after childbirth. Methods: this research was conducted in the electronic databases of MEDLINE, LILACS, EMBASE and Cochrane Library until December 2020, using the terms “vitamin D”, “pregnancy”, “vitamin D deficiency”, “infant”, “newborn” and their synonyms. Randomized controlled trials were searched by evaluating the effects of maternal vitamin D supplementation in neonates. The data was analyzed on RevMan 5.4 software and the quality of evidence on GRADE. Results: the newborn’s overall health condition was presented as Apgar, with a mean difference (MD) of 0.15 (CI95%=0.06-0.25; p=0.002; I2=0%, two studies, 648 participants, moderate quality evidence) at the first minute and 0.11 (CI95%=0.04-0.17; p=0.001; I2=0%, two studies, 648 participants, moderate quality evidence) at the fifth minute. Significant effects were also presented at the length at birth considering any supplemented dose (MD=0.19; CI95%=0.08-0.30; p=0.0010; I2=0%, 1452 participants, low quality evidence) and birth weight in doses higher than 4000IU/day (MD=257.05 (CI95%=137.81-376.29; p<0.0001; I2=14%, 176 participants, moderate quality evidence). Conclusion: vitamin D supplementation during pregnancy improves serum 25 (OH) D concentration and suggests positive effects on overall health condition, length at birth and birth weight. PROSPERO CRD42017073292.
15.
Mental health interventions for suicide prevention among indigenous adolescents: a systematic review
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Grande, Antonio Jose
; Elia, Christelle
; Peixoto, Clayton
; Jardim, Paulo de Tarso Coelho
; Dazzan, Paola
; Veras, Andre Barciela
; Cruickshank, John Kennedy
; Rosa, Maria Inês da
; Harding, Seeromanie
.
ABSTRACT BACKGROUND: The legacies of colonization and of policies of forced assimilation continue to be a cause of intergenerational trauma, manifested through feelings of marginality, depression, anxiety and confusion, which place indigenous peoples at increased risk of suicide. OBJECTIVES: To assess the quality, content, delivery and effectiveness of interventions for preventing suicides among indigenous adolescents. DESIGN AND SETTING: Systematic review conducted with Cochrane methodology, Campo Grande, Mato Grosso do Sul, Brazil. METHODS: The Cochrane library, MEDLINE, EMBASE, CINAHL, LILACS and PsycINFO databases were searched for studies published up to February 2021. The following inclusion criteria were used: published in any language; interventions that aimed to prevent suicides among indigenous adolescents; randomized or non-randomized study with a control or comparative group; and validated measurements of mental health problems. RESULTS: Two studies were identified: one on adolescents in the remote Yup’ik community in south-western Alaska, and the other on Zuni adolescents in New Mexico. Both studies showed evidence of effectiveness in interventions for reducing some of the risk factors and increasing some of the protective factors associated with suicide. High levels of community engagement and culture-centeredness were key anchors of both studies, which ensured that the intervention content, delivery and outcome measurements aligned with the beliefs and practices of the communities. Both studies were judged to have a moderate risk of bias, with biases in sample selection, attrition and inadequate reporting of results. CONCLUSIONS: The current evidence base is small but signaled the value of culturally appropriate interventions for prevention of suicide among indigenous adolescents. REGISTRATION DETAILS: The study protocol is registered in the international prospective register of systematic reviews (PROSPERO); no. CRD42019141754.
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