Abstract Historiographic consideration on the political culture of the late-colonial period and its impact regarding the publication of Sergio Serulnikov's recent book, El poder del disenso, which proposes a long-term revisionist look at the crisis of the Spanish colonial order in the Andes.

Resumen Reflexión historiográfica sobre la cultura política del periodo tardocolonial y su impacto a propósito de la publicación del reciente libro de Sergio Serulnikov, El poder del disenso que propone una mirada revisionista de largo plazo a la crisis del orden colonial español en los Andes.

Resumen Los relevamientos y muestreos arqueológicos de rocas realizados a lo largo de la cuenca del río Atuel (sur de la provincia de Mendoza, Argentina) permitieron identificar fuentes potenciales de aprovisionamiento lítico en tres sectores: cordillera, piedemonte y planicie. Este trabajo articula dicha información con la previamente disponible sobre las características geológicas y litológicas de la cuenca, y con la obtenida en distintos sitios arqueológicos allí emplazados, pertenecientes al Holoceno tardío. El objetivo es caracterizar la base regional de recursos líticos del Atuel e indagar sobre los modos de aprovisionamiento, explotación y circulación de las rocas de la región. Los resultados sugieren que la base regional incidió en los modos de aprovisionamiento en cordillera y piedemonte, mientras que en la planicie intervinieron mecanismos de interacción, como el intercambio de rocas foráneas. Los datos recopilados permiten reconstruir las trayectorias artefactuales de las rocas mayormente utilizadas en los sitios del Atuel (i.e., silíceas, obsidiana, basalto y riolita), lo que es de gran relevancia para los estudios tecnológicos y la contrastación de modelos biogeográficos generados para el sur de Mendoza.

Abstract Archaeological rock surveys and sampling carried out along the Atuel River Basin (southern Mendoza, Argentina) identified potential sources of lithic procurement in three sectors of the basin: mountain range, piedmont, and plain. This paper articulates the information obtained with that previously available on the geological and lithological characteristics of the basin and that from different Late Holocene archaeological sites in the area. The goal is to characterize the regional base of Atuel lithic resources and investigate the modes of procurement, exploitation and circulation of rocks in the region in the past. The results suggest that the regional base influenced the procurement modes in the mountain range and piedmont, while interaction mechanisms, such as the exchange of foreign rocks, intervened in the plain. In addition, the data collected allows the artifactual trajectories of the rocks mostly used in the Atuel sites (i.e., siliceous, obsidian, basalt and rhyolite) to be reconstructed, which is of great relevance for technological studies and the evaluation of different biogeographic models generated for the region.

Abstract This essay responds to the contributions of Vicente Palermo and Roy Hora present in this same issue. issue

Resumen El presente ensayo responde a las contribuciones de Vicente Palermo y Roy Hora presenten en este mismo número. número

Résumé L’agroécologie est un terme qui a une puissance épistémique ou émancipatrice, dans la mesure où il est capable de créer de nouvelles connaissances et des regards alternatifs à la vision imposée par le capital du monde et la nature. Les quatre expériences qui seront analysées dans cet article, se situent dans ce qu’on appelle les processus de transition agroécologique. Bien que ce terme soit en principe fortement associé au développement des pratiques agricoles et se concentre sur les éléments productifs, écologiques et technologiques qui peuvent être utiles pour faire avancer le processus de transition agroécologique, il devient nécessaire d’élargir les dimensions à d’autres niveaux liés à la vie quotidienne des acteurs qui mettent en œuvre ces pratiques. Précisément le présent travail cherche apporter des éléments pour comprendre les formes que peuvent prendre les transitions agroécologiques, à partir de quatre expériences en cours qui se situent dans la province de Santiago del Estero, en Argentine. En guise d’apport final, il identifie les principales dimensions qui sont transversales à celles-ci et sont d’une grande importance pour l’accompagnement des processus de transition et la conception ultérieure d’alternatives sociales, économiques, écologiques et/ou techniques. Lagroécologie L agroécologie émancipatrice nature article quon qu on agroécologique productifs délargir d élargir dautres autres agroécologiques Estero Argentine dapport apport final cellesci celles ci dune laccompagnement l accompagnement dalternatives alternatives sociales économiques etou techniques

Abstract Agroecology is a term that has an epistemic or emancipatory power, insofar as it is capable of creating new knowledge and alternative views to the vision imposed by the capital of the world and nature. The four experiences that will be analyzed in this article, are located in some way in what is called the agroecological transition processes. Although, in principle, this term is strongly associated with the development of agricultural practices and focuses on productive, ecological and technological elements that may be useful to advance in the agroecological transition processes, it is necessary to expand the dimensions to other levels related to the daily life of the actors who carry out these practices. Precisely the present work seeks to contribute elements to understand the forms that agroecological transitions can assume, based on four ongoing experiences that are located in the province of Santiago del Estero, Argentina. As a final contribution, the main dimensions that are transversal to them and are of great importance for accompanying transition processes and the subsequent design of social, economic, ecological and/or technical alternatives are identified. power nature article Although principle productive assume Estero Argentina contribution social economic andor identified

Resumen La agroecología es un término que tiene una potencia epistémica o emancipadora, en cuanto que es capaz de crear nuevos conocimientos y miradas alternativas a la visión que impone el capital del mundo y la naturaleza. Las cuatro experiencias que se analizarán en este artículo, se ubican de alguna forma en lo que se da por llamar los procesos de transición agroecológica. Si bien, este término en principio está asociado fuertemente al desarrollo de prácticas agropecuarias y pone el foco en elementos productivos, ecológicos y tecnológicos que puedan ser útiles para avanzar en el procesos de transición agroecológica, se hace necesario ampliar las dimensiones a otros niveles vinculados con la vida cotidiana de los actores que llevan adelante dichas prácticas. El presente trabajo busca aportar elementos para comprender las formas que pueden asumir las transiciones agroecológicas, a partir de cuatro experiencias en marcha que se ubican en la provincia de Santiago del Estero, Argentina. Como aporte final, se identifican las principales dimensiones que son transversales a las mismas y resultan de gran importancia para el acompañamiento de los procesos de transición y el posterior diseño de alternativas sociales, económicas, ecológicas y/o técnicas. emancipadora naturaleza artículo agroecológica bien productivos agroecológicas Estero Argentina final sociales económicas yo técnicas

ABSTRACT Natural additives, particularly essential oils, have gained widespread recognition for their role in enhancing the attributes of natural edible polymers. Comprising a wealth of hydrophobic and volatile compounds, essential oils exhibit notable antioxidant and antimicrobial properties owing to their rich composition of terpenes and aromatic constituents. This review underscores the multifaceted biological properties of essential oils, encompassing their incorporation into films, edible coatings, and nanoencapsulated materials. The effect of utilizing several essential oils as natural additives in combination with different raw materials and plasticizers was compared to the evaluation of their impact on the material properties of films and edible coatings, offering an in-depth analysis of the specific essential oil variants featured in the recent literature. Among the essential oils reviewed, those derived from clove, cinnamon, and oregano emerge as the predominant choices, representing some of the most promising natural additives for biodegradable packaging. Nanoencapsulation techniques have also expanded the role of essential oils in sustainable food packaging by increasing their stability. polymers compounds constituents coatings indepth depth literature reviewed clove cinnamon choices stability

BACKGROUND The city of El Pedregal grew out of a desert, following an agricultural irrigation project in southern Peru. OBJECTIVES To describe infestation patterns by triatomines and bed bugs and their relationship to migration and urbanization. METHODS We conducted door-to-door entomological surveys for triatomines and bed bugs. We assessed spatial clustering of infestations and compared the year of construction of infested to un-infested households. To gain a better understanding of the context surrounding triatomine infestations, we conducted in-depth interviews with residents to explore their migration histories, including previous experiences with infestation. FINDINGS We inspected 5,164 households for Triatoma infestans (known locally as the Chirimacha); 21 (0.41%) were infested. These were extremely spatially clustered (Ripley’s K p-value < 0.001 at various spatial scales). Infested houses were older than controls (Wilcoxon rank-sum: W = 33; p = 0.02). We conducted bed bug specific inspections in 34 households; 23 of these were infested. These were spatially dispersed across El Pedregal, and no difference was observed in construction age between bed bug infested houses and control houses (W = 6.5, p = 0.07). MAIN CONCLUSIONS The establishment of agribusiness companies in a desert area demanded a permanent work force, leading to the emergence of a new city. Migrant farmers, seeking work opportunities or escaping from adverse climatic events, arrived with few resources, and constructed their houses with precarious materials. T. infestans, a Chagas disease vector, was introduced to the city and colonized houses, but its dispersal was constrained by presence of vacant houses. We discuss how changes in the socioeconomic and agricultural landscape can increase vulnerability to vector-borne illnesses. Peru urbanization doortodoor door uninfested un indepth depth histories 5164 5 164 5,16 known Chirimacha Chirimacha) 2 0.41% 041 0 41 (0.41% Ripleys Ripley s pvalue value 0001 001 0.00 scales. scales . scales) Wilcoxon ranksum rank sum rank-sum 33 0.02. 002 0.02 02 0.02) 3 65 6 6.5 0.07. 007 0.07 07 0.07) force farmers events resources materials T vector vectorborne borne illnesses 516 16 5,1 0.41 04 4 (0.41 000 00 0.0 6. 51 1 5, 0.4 (0.4 0. (0. (0 (

RESUMO Introdução: A doença de Fabry (DF) é um erro inato do metabolismo caracterizado pela deficiência da enzima α-galactosidase A. O objetivo primário foi avaliar o perfil genético e fenotípico da doença de Fabry em hemodiálise. Métodos: Estudo de coorte observacional para determinar a incidência de variações genéticas e alterações fenotípicas para DF em pacientes em hemodiálise no Vale do Paraíba e Zona Leste de São Paulo. O teste genético para o gene GLA foi realizado para homens e mulheres em todos os pacientes das clínicas de hemodiálise maiores de 12 anos entre janeiro de 2016 a dezembro de 2019 como protocolo de rastreio. Resultados: Os casos foram provenientes de exames de triagem do caso índice entre pacientes portadores de doença renal crônica, resultando em 17 famílias e totalizando 82 pacientes em estudo. A classificação da variante mais prevalente foi a de significado incerto (54%), seguida da variante patogênica (46%). Foram descritos 5 pacientes em duas famílias com dois tipos de variantes ainda não previamente descritos na literatura com comportamento patogênico. Na comparação entre os tipos de variantes, a presença de variante patogênica foi associada a maiores níveis de lysoGB3, menores valores da atividade da alfa-GAL e maior frequência de sintomas relativos à DF. Conclusão: Caracterizamos uma extensa população de pacientes com variantes para DF com riqueza de detalhes de genética, clínica e de biomarcadores. Acreditamos que este estudo possa auxiliar na melhor caracterização da população brasileira com DF e nos tipos mais frequentes de variantes. Introdução (DF αgalactosidase α galactosidase Métodos Paulo 1 201 rastreio Resultados crônica 8 54%, 54 54% , (54%) 46%. 46 46% . (46%) patogênico lysoGB3 lysoGB alfaGAL alfa GAL Conclusão genética biomarcadores 20 (54% 4 (46% 2 (54 (46 (5 (4 (

ABSTRACT Introduction: Fabry disease (FD) is an inborn error of metabolism characterized by α-galactosidase A deficiency. The primary objective was to evaluate the genetic and phenotypic profile of Fabry disease in hemodialysis. Methods: Observational cohort study to determine the incidence of genetic variations and phenotypic changes for FD in hemodialysis patients in the Paraiba Valley and Eastern São Paulo. Genetic testing for the GLA gene was performed for men and women over 12 years of age at the hemodialysis clinics between January 2016 and December 2019 as a screening protocol. Results: The cases came from screening exams of the index case among patients with chronic kidney disease, resulting in 17 families and totaling 82 patients under study. The classification of the most prevalent variant was that of uncertain significance (54%), followed by the pathogenic variant (46%). Five patients in two families were described with two types of variants not previously described in the literature, with pathogenic behavior. Comparing the types of variants, the presence of a pathogenic variant was associated with higher levels of lysoGB3, lower values for alpha-GAL activity and higher frequency of symptoms related to FD. Conclusion: We characterized an extensive population of patients with FD variants with rich genetic, clinical and biomarker details. We believe that this study can help to better characterize the Brazilian population with FD and the most frequent types of variants. Introduction (FD αgalactosidase α galactosidase deficiency Methods Paulo 1 201 protocol Results 8 54%, 54 54% , (54%) 46%. 46 46% . (46%) literature behavior lysoGB3 lysoGB alphaGAL alpha GAL Conclusion details 20 5 (54% 4 (46% 2 (54 (46 (5 (4 (

ABSTRACT: Objective: To compare and validate diagnostic systems for the severity of Osteoarthrosis (OA) of the temporomandibular joints (TMJ) in computed tomography (CT) images. Method: An observational, retrospective, analytical, blinded, retrospective study was performed. Ninety-nine patients (198MSCT-ATM) were evaluated, applying the criteria of seven different diagnostic systems. A calibrated clinician (K=0.7) performed the evaluations. Content validity was performed under the Ahmad criteria. Internal consistency was determined with Cronbach’s Alpha. Data were correlated with Spearman’s Rho. Results: For condylar erosion severity, there was a high positive correlation between Alexiou/Arayasantiparb (rho=0.986) and a low one between Cömert/Alexiou (rho=0.421) and Cömert/Arayasantiparb (rho=0.422) classifications. For condylar sclerosis, we found a strong correlation between Cömert/Alexiou, Masilla/Alexiou and Cömert/Masilla classifications (rho=857; rho=0.853; rho=0.998). The data presented high internal consistency (Cronbach’s alpha=0.897) and low content validation (36.2%). Conclusions: The measurements of the 7 systems have a high reliability. Bone erosion, sclerosis and osteophytes are measured at four levels of severity and with a similar scale in three diagnostic systems (Alexiou, Arayasantiparb and Cömert). We suggest to complement it with the determination of joint space and condylar mobility, as proposed by RDC/TMD. Content validity was low, only the Cömert and Alexiou diagnostic systems were higher than 50%.

RESUMEN: Objetivo: Comparar y validar sistemas diagnósticos de severidad de Osteoartrosis (OA) de las articulaciones temporomandibulares (ATM) en imágenes de tomografía computada (TAC). Método: Se efectuó un estudio observacional, retrospectivo, analítico y ciego. Se evaluaron 99 pacientes (198TAC-ATM), aplicando los criterios de siete diferentes sistemas diagnósticos. Un clínico calibrado (K=0,7) efectuó las evaluaciones. La validez de contenido se efectuó bajo los criterios Ahmad. La consistencia interna se determinó con Alpha de Cronbach. Se correlacionaron los datos con Rho de Spearman. Resultados: La severidad de la erosión condilar presenta alta correlación positiva entre las clasificaciones Alexiou/Arayasantiparb (rho=0,986) y baja entre Cömert/Alexiou (rho=0,421) y Cömert/Arayasantiparb (rho=0,422). La esclerosis condilar presentó fuerte correlación entre las clasificaciones de Cömert/Alexiou, Masilla/Alexiou y Cömert/Masilla (rho=857;rho=0,853;rho=0,998). Los datos presentaron alta consistencia interna (Alfa Cronbach=0,897) y baja validación de contenido (36,2%). Conclusiones: Las mediciones de los 7 sistemas presentan alta fiabilidad. La erosión ósea, esclerosis y osteofitos son medidos en cuatro niveles de severidad y con similar escala en tres sistemas de diagnóstico (Alexiou, Arayasantiparb y Cömert), sugiriendose complementar con determinación del espacio articular y movilidad condilar, como propone RDC/TMD para TTM. La validación de contenido fue baja, solo los sistemas diagnósticos de Cömert y Alexiou superaron el 50%.

Resumen Uno de los vectores del paradigma de la modernización es que una sociedad sólo es moderna si desaparecen costumbres y prácticas tradicionales para dar lugar al desarrollo económico. En ese marco, resulta difícil entender la realidad de sectores productivos como la agricultura familiar, que se sustentan sobre conocimientos y formas tradicionales de producción. El objetivo del trabajo es analizar un caso a partir del enfoque de estilos agrícolas que permite captar las prácticas llevadas a cabo por los actores en un contexto moderno teniendo en cuenta la capacidad productiva y el grado de incorporación a los mercados. La metodología combina técnicas cuantitativas y cualitativas de investigación, y las conclusiones son dos: primero, la caracterización de los estilos atiende a aspectos que son más representativos de la realidad; segundo, permite identificar circuitos agroalimentarios alternativos locales, lo que posibilita en los agricultores una manera particular de integrarse al sistema moderno globalizado.

Abstract One of the vectors of the paradigm of modernization is that a society is only modern if traditional customs and practices disappear to give way to economic development. Within this framework, it´s difficult to understand the reality of productive sectors such as family farming that are based on knowledge and traditional forms of production. The aim of the work is to analyze a case from the approach of farming styles that allows capturing practices carried out by the actors in a modernization context taking into account the productive capacity and the degree of incorporation into the markets. The methodology combines quantitative and qualitative research techniques and the conclusions are two: first, that the characterization of the styles addresses aspects that are more representative of reality and second, it makes it possible to identify alternative local agri-food circuits, enabling farmers to have a particular way of integrate into the modern globalized system.

SUMMARY OBJECTIVE: This study aimed to analyze the evidence and controversies about the use of vaginal energy-based devices (laser and radiofrequency) for treatment of genitourinary syndrome of menopause, recurrent urinary tract infection, urinary incontinence, and genital prolapse through a literature review. METHODS: A search of literature databases (PubMed, Medline) was performed for publications in December 2022. Keywords included genitourinary syndrome of menopause, vaginal laxity, vaginal/vulvovaginal atrophy, urinary tract infection, urgency incontinence, frequency, urgency, stress urinary incontinence, genital prolapses AND energy-based devices, AND vaginal laser, AND vaginal radiofrequency, AND CO2 laser, AND Er:YAG laser. Publications in English from the last 7 years were reviewed and selected by the authors. RESULTS: The literature regarding vaginal energy-based devices in the treatment of urogynecological conditions is primarily limited to prospective case series with small numbers and short-term follow-up. Most of these studies showed favorable results, improvement of symptoms with low risk, or no mention of serious adverse events. Consensus statement documents from major medical societies suggest caution in recommending these therapies in clinical practice until more relevant data from well-designed studies become available. CONCLUSION: The potential of the vaginal laser and radiofrequency as a therapeutic arsenal for the evaluated urogynecological conditions is great, but qualified research must be done to prove their efficacy and long-term safety, define application protocols, and recommend the use of these technologies in clinical practice. OBJECTIVE energybased energy based menopause infection incontinence review METHODS PubMed, PubMed (PubMed Medline 2022 laxity vaginalvulvovaginal vulvovaginal atrophy frequency CO ErYAG Er YAG authors RESULTS shortterm short term followup. followup follow up. up follow-up results risk events welldesigned well designed available CONCLUSION great longterm long safety protocols 202 20 2

Abstract The present work aimed to characterize and compare the catalytic properties of amylases from Cunninghamella echinulata and Rhizopus microsporus. The highest production of amylase by C. echinulata, 234.94 U g-1 of dry substrate (or 23.49 U mL-1), was obtained using wheat bran as a substrate, with 50–55% initial moisture and kept at 28 °C for 48 h. The highest production of amylases by R. microsporus, 224.85 U g-1 of dry substrate (or 22.48 U mL-1), was obtained cultivating wheat bran with 65% initial moisture at 45 °C for 24 h. The optimal activity of the amylases was observed at pH 5.0 at 60 °C for C. echinulata enzymes and at pH 4.5 at 65 °C for R. microsporus. The amylases produced by C. echinulata were stable at pH 4.0–8.0, while the R. microsporus enzymes were stable at pH 4.0–10.0. The amylases produced by C. echinulata remained stable for 1 h at 50 °C and the R. microsporus amylases maintained catalytic activity for 1 h at 55 °C. The enzymatic extracts of both fungi hydrolyzed starches from different plant sources and showed potential for liquefaction of starch, however the amylolytic complex of C. echinulata exhibited greater saccharifying potential. C 23494 234 94 234.9 g1 g g- or 2349 23 49 23.4 mL1, mL1 mL , mL-1) 5055 50–55 2 4 R 22485 224 85 224.8 2248 22 22.4 5 0 5. 6 4. 4080 8 4.0–8.0 40100 10 4.0–10.0 starch 9 234. 23. mL-1 505 50–5 224. 22. 408 4.0–8. 4010 4.0–10. mL- 50– 40 4.0–8 401 4.0–10 4.0– 4.0–1 4.0

Resumen En el presente artículo se estudian los conceptos de imagen y representación en la filosofía de Ernst Cassirer. En este texto se hace patente el valor simbólico con el cual el neokantiano define a las imágenes. A partir de ello, se explica cómo éstas pueden presentarse como una relación de identidad entre un objeto definido y el concepto construido por un agente epistémico. Para ilustrar dicha teoría, se considera el funcionamiento del Tomógrafo Axial Computarizado (TAC) para mostrar que la finalidad de las imágenes médicas es representar la realidad de forma digital, para lo cual se requiere únicamente simbolizar la forma del cuerpo. Finalmente, se sugiere el uso del Efecto Doppler como método alternativo a considerar en el funcionamiento del TAC.

Abstract This article studies the concepts of image and representation in Ernst Cassirer’s philosophy. In this text the symbolic value with which the neo-Kantian defines images becomes evident. Based on this, it is explained how these can be presented as a relationship of identity between a defined object and the concept constructed by an epistemic agent. To illustrate such theory, the operation of the Computed Axial Tomography (CAT) is considered to show that the purpose of medical images is to represent reality digitally, for which it is only required to symbolize the shape of the body. Finally, the use of the Doppler Effect is suggested as an alternative method to consider in the operation of the CAT.

Resumen Objetivo: Mostrar las estrategias agroecológicas desplegadas por agroecosistemas de la agricultura campesina, tendientes a captar el trabajo/energía producido por la naturaleza y transformarlo en valor, con la participación escasa o nula del capital en tales procesos. Metodología: El estudio del caso responde a un método de investigación cualitativa a partir de entrevistas y observaciones directas Resultados: Los procesos de no mercantilización, la condición bifacética de la mano de obra familiar, los tiempos del capital y los de la naturaleza, el capital como cosa y como proceso, la inmediatez tanto del proceso de trabajo, del producto de trabajo y de la realización del valor de uso conjuntamente con formas de apropiación y gestión comunal de la tierra y recursos asociados, son aspectos que sientan la base para pensar en la agroecología contrahegemónica. Limitaciones: Más estudios de caso permitirían abordar estas perspectivas que tienen una fuerte mirada capitalocentrico e integrar y complementar con otras miradas y disciplinas. Conclusiones: Comprender la lógica del capital desde su relación con la naturaleza y como la naturaleza puede trabajar para ciertos agroecosistemas, disminuyendo el carácter disciplinador del capital en tales procesos, constituye un tema a considerar para el diseño de políticas por parte de los movimientos sociales.

Abstract Objective: To show the agroecological strategies deployed by agroecosystems of peasant agriculture, tending to capture the work/energy produced by nature and transform it into value, with little or no participation of capital in such processes. Methodology: The case study responds to a qualitative research method based on interviews and direct observations. Results: The processes of non-commodification, the bifaceted condition of family labor, the times of capital and those of nature, capital as a thing and as a process, the immediacy of both the work process, the work product, and the realization of use value together with forms of appropriation and communal management of the land and associated resources, all of it are aspects that lay the groundwork for thinking about counter-hegemonic agroecology. Limitations: More case studies would allow us to address these perspectives that have a strong capitalocentric perspective and integrate and complement other perspectives and disciplines. Conclusions: Understanding the logic of capital from its relationship with nature and how nature can work for certain agroecosystems, reducing the disciplining nature of capital in such processes, is an issue to consider for the design of policies by social movements.

Abstract: The south of Mendoza province has been characterized as the southern frontier of South American pre-Hispanic agriculture on the eastern slope of the Andes. This characterization has been based on the presence of crops at the archaeological sites and adopting a dichotomic perception of hunter-gatherers and farmers. During the last few decades, the archaeological record has shown a complex and shifting situation both at a spatial and temporal level in relation to the dependence of human groups on this type of resource. Based on a biogeographic model, we evaluated different lines of analysis from the archaeological record to assess the impact of environmental factors on the emergence of agriculture within the region. The results obtained confirm the low importance of agriculture among human groups as well as their flexibility in facing different environmental and demographic scenarios. Finally, we propose that the environmental structure of Patagonia would have played a central role in limiting the spread of domesticated plant use in this region of South America.

Resumen: El sur de la Provincia de Mendoza ha sido caracterizado como el límite meridional de la agricultura prehispánica sudamericana, específicamente en la vertiente oriental de los Andes. Dicha caracterización ha estado basada en la presencia de plantas domesticadas en los sitios arqueológicos, utilizando una mirada dicotómica entre cazadores-recolectores y agricultores. Los trabajos arqueológicos de las últimas décadas han mostrado una situación compleja y cambiante tanto a nivel espacial como temporal en relación a la dependencia de los grupos humanos sobre este tipo de recursos. A partir de un modelo biogeográfico, se utilizan distintas líneas de análisis del registro arqueológico con el fin de evaluar la incidencia del contexto ambiental en el ingreso de la agricultura a la región. Los resultados obtenidos confirman la escasa importancia de los recursos domesticados entre los grupos humanos de la región y la flexibilidad mostrada por los mismos para enfrentar distintos escenarios ambientales y demográficos. Finalmente, se propone que, en el sur de Mendoza, la estructura ambiental del área biogeográfica de Patagonia habría tenido un rol central en los límites para la dispersión de las plantas domesticadas en esta región de América del Sur.

ABSTRACT The goal of this paper is to describe an archaeological burial site with commingled skeletal remains, named Cañada Seca-1 (MNI= 24), located in the Atuel River valley and dating from ca.1500yearsBP. This isperformedby integrating well-known and recently developed lines of inquiry.Based on this record, we discuss interpretations related to cultigen presence and its implicationsin human subsistence and mobility, in an area traditionally characterized as the pre-Hispanicagricultural limit, ca. 2200 years BP. Results show that the individuals did not developed a farmingstrategy, although maize seems to have been part of their diet. In turn, the new information aboutmortuary behavior in the Atuel River valley provides new insights regarding mobility, as well asthe use of utilitarian (lithics) and nonutilitarian (lithic and malacological ornaments) technologythat went beyond these peoples' life into their death.

RESUMEN Este trabajo tiene como objetivo caracterizar el sitio Cañada Seca-1, un entierro múltiple (NMI=24) localizado en el valle del Atuel y fechado en ca. 1500 años AP, a través de la integración de diferentes líneas de evidencia. A partir de este registro se discuten las interpretacionesen torno a la presencia de cultígenos y sus implicancias para la subsistencia humana en unárea caracterizada tradicionalmente como el límite de la dispersión agrícola sudamericana,ca. 2200 años AP. Los resultados destacan que los individuos inhumados en el sitio no habríandesarrollado una estrategia fundamentalmente agrícola, aunque el maíz formó parte de su dieta.Además, la nueva información sobre los comportamientos mortuorios en la zona del valle delAtuel, ofrece evidencias tanto sobre movilidad como sobre el uso de tecnologías utilitarias (líti-cas) y no utilitarias (ornamentos líticos y malacológicos) que trascendieron la vida cotidiana ylos acompañaron en la muerte.