Resumo O objetivo é estimar prevalência de componentes da sarcopenia e associações com variáveis socioeconômicas em idosos de população rural do Ceará. Estudo transversal com 274 idosos. Massa muscular foi determinada por Índice de Massa Muscular (IMM) por bioimpedância elétrica e por circunferência da panturrilha; força muscular (FM) por teste de preensão palmar; e desempenho físico por testes da caminhada (VC) e Timed-up-and-go. Provável sarcopenia foi caracterizada por diminuição da FM, sarcopenia quando associada a diminuição do IMM, e sarcopenia grave quando estes dois foram acompanhados de baixa VC. Foram estimadas associações entre condições sociodemográficas, hábitos de vida e componentes da sarcopenia. Na regressão logística, foi observada frequência mais elevada: i) no sexo masculino, idade>69 anos, e nos que não trabalham, entre os idosos com FM diminuída; ii) com idade>69 anos, nos que não moram com o cônjuge, e nos que não praticam atividade física num nível adequado, entre os idosos com IMM diminuído; iii) com idade>69 anos, nos que residem na zona rural há menos que 30 anos, e nos que não trabalham, entre os idosos com VC diminuída. Ceará 27 (IMM panturrilha (FM palmar (VC Timedupandgo. Timedupandgo Timed up and go. go Timed-up-and-go sociodemográficas logística elevada i masculino idade69 idade 69 idade>6 anos trabalham diminuída ii cônjuge adequado diminuído iii 3 2 idade6 6 idade>

Abstract The aim is to determine the prevalence of sarcopenia components and associations with socioeconomic variables in older persons living in rural areas in the state of Ceará, Brazil. We conducted a cross-sectional study with 274 older adults. Muscle mass was assessed using muscle mass index (MMI), measured by bioelectrical impedance analysis and calf circumference. Muscle strength (MS) was assessed using the handgrip test. Physical performance was measured using the walk test to calculate gait speed (GS) and the timed up-and-go test. Probable sarcopenia was defined as the presence of low MS, while confirmed sarcopenia was defined as the presence of low MS and low MMI. Severe sarcopenia was defined as the presence of the latter two criteria and slow GS. We tested for associations between sociodemographic characteristics and lifestyle habits and the components of sarcopenia. The logistic regression produced the following results: i) prevalence of low MS was higher among men, individuals aged >69 years, and in those not working at the time of the study; ii) the prevalence of low MMI was higher in individuals aged >69 years, those not living with a spouse, and those with an inadequate level of physical activity; iii) the prevalence of slow GS was higher in individuals aged >69 years, those who had lived in rural areas for less than 30 years, and those not working at the time of the study. Ceará Brazil crosssectional cross sectional 27 adults MMI, , (MMI) circumference (MS (GS upandgo up go results i men 69 >6 years ii spouse activity iii 3 2 (MMI 6 >

Abstract The aim is to determine the prevalence of sarcopenia components and associations with socioeconomic variables in older persons living in rural areas in the state of Ceará, Brazil. We conducted a cross-sectional study with 274 older adults. Muscle mass was assessed using muscle mass index (MMI), measured by bioelectrical impedance analysis and calf circumference. Muscle strength (MS) was assessed using the handgrip test. Physical performance was measured using the walk test to calculate gait speed (GS) and the timed up-and-go test. Probable sarcopenia was defined as the presence of low MS, while confirmed sarcopenia was defined as the presence of low MS and low MMI. Severe sarcopenia was defined as the presence of the latter two criteria and slow GS. We tested for associations between sociodemographic characteristics and lifestyle habits and the components of sarcopenia. The logistic regression produced the following results: i) prevalence of low MS was higher among men, individuals aged >69 years, and in those not working at the time of the study; ii) the prevalence of low MMI was higher in individuals aged >69 years, those not living with a spouse, and those with an inadequate level of physical activity; iii) the prevalence of slow GS was higher in individuals aged >69 years, those who had lived in rural areas for less than 30 years, and those not working at the time of the study.

Resumo O objetivo é estimar prevalência de componentes da sarcopenia e associações com variáveis socioeconômicas em idosos de população rural do Ceará. Estudo transversal com 274 idosos. Massa muscular foi determinada por Índice de Massa Muscular (IMM) por bioimpedância elétrica e por circunferência da panturrilha; força muscular (FM) por teste de preensão palmar; e desempenho físico por testes da caminhada (VC) e Timed-up-and-go. Provável sarcopenia foi caracterizada por diminuição da FM, sarcopenia quando associada a diminuição do IMM, e sarcopenia grave quando estes dois foram acompanhados de baixa VC. Foram estimadas associações entre condições sociodemográficas, hábitos de vida e componentes da sarcopenia. Na regressão logística, foi observada frequência mais elevada: i) no sexo masculino, idade>69 anos, e nos que não trabalham, entre os idosos com FM diminuída; ii) com idade>69 anos, nos que não moram com o cônjuge, e nos que não praticam atividade física num nível adequado, entre os idosos com IMM diminuído; iii) com idade>69 anos, nos que residem na zona rural há menos que 30 anos, e nos que não trabalham, entre os idosos com VC diminuída.

RESUMO: Objetivou-se avaliar o grau de ativação e relaxamento muscular de equinos de patrulhamento submetidos à exercícios de mobilização dinâmica associados ou não à acupuntura. Doze cavalos castrados, sem raça definida, com idade de 10 ± 2,0 anos, foram distribuídos em três tratamentos: tratamento com uma sessão única de exercícios de mobilização dinâmica (flexão cervical longitudinal da cabeça entre os cascos, entre os carpos e até o peito); tratamento com sessão única de acupuntura (20 minutos); e tratamento com sessão única composta por exercícios de mobilização dinâmica associados a acupuntura. Foram analisadas imagens termográficas antes e após a aplicação dos tratamentos das regiões cervical, torácica, dorsal, abdominal e pélvica. A avaliação comportamental foi obtida por meio de filmagens 5 minutos antes e 10 minutos após o término da aplicação dos tratamentos, de maneira ininterrupta. Houve aumento (P < 0,0001) na temperatura corporal dos animais ao final da sessão única de exercícios funcionais para todas as regiões estudadas, sendo a cervical e torácica aquelas com maior valor de temperatura final. Não houve variação da temperatura nos demais tratamentos (P > 0,05). Todos os tratamentos geraram maior frequência (P < 0,05) na expressão de comportamentos relacionados ao relaxamento. A realização de uma sessão única de exercícios de mobilização dinâmica é suficiente para promover uma intensa resposta muscular em todo o corpo do equino, e tanto os exercícios funcionais quanto a acupuntura, de maneira individual ou associada, foram capazes de promover relaxamento muscular e mental, interferindo de maneira positiva no bem-estar dos animais.

ABSTRACT: The present research evaluated muscle activation degrees and relaxation of patrolling horses submitted to dynamic mobilization exercises, associated or not with acupuncture. Twelve mixed breed gelding, aged 10 ± 2.0 years, were distributed in three treatments. Treatment with a single session of dynamic mobilization exercises (longitudinal cervical flexion of head between hooves, between carpus and to up to chest); treatment with a single acupuncture session during 20 minutes, and treatment with a single session of dynamic mobilization exercises with acupuncture. Thermographic images were analyzed before and after applying treatments to the cervical, thoracic, dorsal, abdominal and pelvic regions. Animal behavior was assessed through five minutes filming, before and ten minutes after the end of each treatment application, in an uninterrupted way. Increase in animals body temperature at the end of the single session of functional exercises (P < 0.0001) at all animal regions were reported, being cervical and thoracic areas with highest final temperature values. There was no temperature variation for other treatments (P > 0.05). All treatments stimulated higher expression frequency (P < 0.05) of relaxation behaviors. A single dynamic mobilization exercises session is enough to promote intense muscular response in entire horse body; and with acupuncture, individually or associated, promoted muscle and mental relaxation, interfering positively in animal welfare.

Abstract Microalgae are considered a rich source of biostimulants for plants, as an excellent business opportunity for the agricultural sector, as they can activate plant metabolism, contributing to the improvement in physiological performance, phytomass and, subsequently, vigor and quality of seedlings. The objective of this work was to evaluate the potential of Spirulina platensis biomass, in enabling improvements in physiological performance, phytomass and, subsequently, vigor and quality of cashew rootstock seedlings. The experiment was carried out in a greenhouse in a completely randomized design, in a 4 x 2 factorial scheme (concentrations x rootstock), with three replications. The concentrations used were 0%, 0.04%, 0.08%, and 0.12% and the FAGA and CCP 76 genotypes. The seeds were immersed in the solutions for 12 hours. Applications were made via the leaves at 30 days after sowing (DAS), with an interval of seven days between each application and at 90 DAS evaluations were made. The FAGA and CCP 76 genotypes showed a positive response to the supply of S. platensis, with concentrations 0.04% and 0.08% which provided greater root length, aerial part length, number of leaves, diameter and leaf area. Concentrations 0.04% and 0.08% also promoted better percentages in the physiology of the CCP 76 genotype, while the FAGA genotype showed opposite action, which may be related to the mode of action of the microalgae on the different genetic and phenotypic characteristics of each genotype. The 0.12% concentration provided greater accumulations of aerial part and total dry mass to the genotypes.

Abstract The effect of high dietary lipid on the meat quality parameters of shoulder meat adult goats in raw meat and during curing and smoking was evaluated by classical and multivariate approaches. The animals were divided into two groups of different finishing strategies: without whole full-fat linseed (WFFLG, n = 9) and whole full-fat linseed (FFLG, n = 9), with diets containing an ether extract content of 2.7% and 6.9%, respectively. The physicochemical attributes did not vary according to the experimental diets in raw meat. The colorimetric parameters and pH varied during curing and smoking. Through multivariate analysis the first two principal components (PC), it was possible to identified variables were highly importance the total variation (L*, a*, b*, C*, h*, and fat content) in raw meat and smoking. The fat content and color b* presented the highest scores for importance of the variable in the projection. Lipid supplementation of adult goats did not influence the quality parameters physicochemical of the raw shoulder meat. However, after curing and smoking there was a significant effect of diet on Hue angle (h*).

RESUMO Objetivo: Investigar evidências de validade de conteúdo e confiabilidade da versão brasileira da Nutritional Literacy Scale (NLS) após processo de adaptação cultural. Métodos: Estudo psicométrico com 1197 usuários do Sistema Único de Saúde (SUS). A NLS foi adaptada culturalmente para a língua portuguesa do Brasil e seis itens da escala original foram modificados para melhorar seu entendimento, originando a versão brasileira da escala, denominada NLS-BR. A análise das evidências de validade de conteúdo da NLS-BR se deu via Teoria de Resposta ao Item (TRI). Resultados: A versão final da NLS-BR ficou com 23 itens e se mostrou adequada para avaliar letramento nutricional em adultos brasileiros atendidos pelo SUS. Considerações finais: A NLS-BR mostrou-se de entendimento adequado, podendo ser considerada com evidências de validade de conteúdo e dotada de confiabilidade para usuários do SUS.

ABSTRACT Objective: To investigate the evidence of content validity and reliability of the Brazilian version of the Nutritional Literacy Scale (NLS) after the cultural adaptation process. Methods: Psychometric study of 1,197 users of the National Health Service (Brazilian SUS). The NLS was culturally adapted to Brazilian Portuguese and six items of the original scale were modified to improve its understanding, giving rise to the Brazilian version of the scale named NLS-BR. The analysis of evidence of content validity of the NLS-BR was performed using the Item Response Theory (IRT). Results: The final version of the NLS-BR had 23 items and proved to be adequate to assess nutritional literacy in adults assisted by the Brazilian SUS. Final considerations: The NLS-BR proved to be of adequate understanding and demonstrated evidence of content validity and reliability for users of the Brazilian SUS.

RESUMEN Objetivo: Investigar las evidencias de la validez de contenido y confiabilidad de la versión brasileña de la Nutritional Literacy Scale (NLS) después del proceso de adaptación cultural. Métodos: Estudio psicométrico con 1197 usuarios del Servicio Nacional de Salud (SUS brasileño). La NLS fue adaptada culturalmente al portugués brasileño y seis ítems de la escala original fueron modificados para mejorar su comprensión, dando origen a la versión brasileña de la escala, denominada NLS-BR. El análisis de evidencia de validez de contenido del NLS-BR se realizó utilizando la Teoría de Respuesta al Ítem (TRI). Resultados: La versión final de la escala NLS-BR tenía 23 ítems y se mostró adecuada para evaluar la educación nutricional en adultos atendidos en el SUS brasileño. Consideraciones finales: La escala NLS-BR demostró ser de comprensión adecuada y tener evidencias de validez de contenido y confiabilidad para los usuarios del SUS brasileño.

The lipase from Rhizomucor miehei (RML) has been immobilized on chitosan-based hybrid (sodium alginate or carrageenan) matrices activated with glycidol (GLY), epichlorohydrin (EPI) or glutaraldehyde (GLU) groups. Then, the properties of the different biocatalysts have been evaluated and compared with the soluble RML. Thermal stability (at pH 7.0 and 60 °C) was significantly increased when compared to the soluble enzyme: 154-fold for chitosan 5.0% - GLU, 80-fold for chitosan 2.5% - carrageenan 2.5% - GLY and 93-fold for chitosan 2.5% - alginate 2.5% - EPI. The best biocatalyst preparation, which was 154-fold more stable than the soluble enzyme, was obtained when RML was immobilized on chitosan activated with glutaraldehyde 5.0% v/v. According to the results, it was concluded that RML immobilization on chitosan-based hybrid matrices using different chemistries greatly produced biocatalysts with different properties.

RESUMO Contexto Medicinas Complementares e Alternativas (MAC) são práticas de cuidados não convencionais que, segundo a Organização Mundial da Saúde, devem ser implementadas no sistema de saúde, particularmente nas regiões pobres do País. No Brasil, têm sido inseridas na saúde como Práticas Integrativas por meio de programas assistenciais e no ensino de graduação. Objetivou-se avaliar o processo de ensino-aprendizagem em Práticas Integrativas nas escolas médicas brasileiras. Metodologia Um estudo transversal foi realizado em escolas médicas brasileiras com um questionário autoaplicável para professores, e um levantamento de dados secundários foi obtido em websites de escolas médicas e instituições de bancos de dados governamentais. Na apresentação das variáveis utilizou-se a distribuição de frequências e os testes do coeficiente de Pearson (x2) – Qui-Quadrado. As proporções foram comparadas por meio do teste Qui-Quadrado ou do Teste Exato de Fisher. Quando o valor esperado de uma tabela de contingência foi igual ou superior a 5, utilizou-se o teste Qui-Quadrado; em todas as outras situações, utilizou-se o Teste Exato de Fisher. A diferença entre as proporções foi estimada pela Odds Ratio, calculada por meio de regressão logística simples (95% IC). Resultados Das 272 escolas médicas do Brasil, 57 abordam MAC, sendo essa proporção maior nas regiões Sul e Centro-Oeste. Há uma concentração de escolas médicas em capitais, e a Região Nordeste apresenta uma concentração significativa de escolas médicas com MAC nas capitais. O número de escolas com metodologias ativas e tradicionais no ensino de MAC é equivalente. A homeopatia, a acupuntura e a medicina integrativa predominam, com uma minoria usando práticas indígenas, cromoterapia e medicina antroposófica. As novas diretrizes educacionais não causaram impacto no número de escolas com MAC. O crescimento em MAC foi insignificante (p < 0, 5) nos últimos dez anos. Conclusão Não houve crescimento no ensino em Práticas Integrativas e Complementares no Brasil na graduação médica após as novas diretrizes curriculares, mesmo diante das necessidades do sistema de saúde.

ABSTRACT Context Complementary and Alternative Medicine (CAM) are unconventional care practices that, according to the World Health Organization, should be implemented in the Health System, particularly in poor regions of the country. In Brazil, they have been adopted by Care Programs and introduced into undergraduate medical education. In this study we were interested in evaluating the teaching-learning process of Integrative Practices in Brazilian medical schools. Methodology A cross-sectional study was carried out at Brazilian medical schools with a self-administered questionnaire for teachers and a secondary data survey was obtained from medical school websites and government database institutions. For the presentation of the variables, frequency distribution and the Pearson coefficient (X2) -Chi-square tests were used. The proportions were compared using the Chi-square test or the Fisher’s Exact Test. When the expected value of a contingency table was equal to or greater than 5, the Chi-square test was used; in all other situations, Fisher’s Exact Test was used. The difference between proportions was estimated by the Odds Ratio, calculated through simple logistic regression (95% CI). Results 57 of the 272 medical schools in Brazil address CAM, with it being proportionally higher in the South and Mid-West regions. The medical schools are highly concentrated in state capitals, and the Northeast region presents a significant concentration of medical schools with CAM in the capitals. The number of schools with active and traditional methodologies in CAM is equivalent. Homeopathy, Acupuncture and Integrative Medicine predominate, with a minority using Indigenous Practices, Chronotherapy and Anthroposophic Medicine. The new educational guidelines have not affected the number of schools with CAM. Growth in CAM has been insignificant (p <0.05) in the last ten years. Conclusion There has been no growth in teaching Complementary and Alternative Medicine in undergraduate medical training in Brazil since the introduction of the new curricular guidelines, even in view of the needs of the health system.

Resumen El objetivo en este estudio fue determinar el contenido de nutrientes en plantas de Myrciaria dubia como respuesta a la aplicación de cinco dosis de K2O (0; 40; 80; 120 e 160 kg ha-1) aplicadas por fertirrigación. Se evaluaron los contenidos de materia seca de hoja (MSH), materia seca total (MST) y el contenido de nutrientes en las hojas. La MSH y la MST fueron mayores en plantas fertilizadas con la dosis de 160 kg ha-1 de K2O, con 52.44 g y 302.69 g, respectivamente. Los contenidos de N y K fueron de 22.15 y 9.48 g kg-1 en respuesta a la dosis de 160 kg ha-1 de K2O. Los contenidos medios de P, Ca y S fueron de 1.6, 17.89 y 1.61 g kg-1, respectivamente, y el contenido de Mg2+ disminuyó desde 5.62 hasta 2.74 g kg-1 en la dosis de 0 y 160 kg ha-1 de K2O, respectivamente. Los contenidos de B, Mn y Fe disminuyeron de 136.5 a 100.0, de 346.24 a 248, y de 142.06 a 97.35 mg kg-1 en la dosis de 0 y 160 kg ha-1 de K2O, respectivamente. Los contenidos medios de Cu y Zn fueron 3,81 y 40,54 mg kg- 1, respectivamente, en todas las dosis de K2O. El contenido de nutrientes determinado en las hojas de M. dubia fueron adecuados para el desarrollo de la especie en el primer año de cultivo, presentando el siguiente orden decreciente: N> Ca> K> Mg> P = S> Mn> B > Fe> Zn> Cu.

Abstract The objective in this study was to determine the nutrient contents in Myrciaria dubia plants in function of five K2O doses (0, 40, 80, 120 and 160 kg ha-1) applied through fertigation. Leaf dry matter (LDM), total dry matter (TDM), and leaf nutrient contents were evaluated. The LDM and TDM were higher in plants subjected to the dose of 160 kg ha-1 of K2O, with 52.44 g and 302.69 g, respectively. Leaf N and K contents were 22.15 and 9.48 g kg-1 in response to 160 kg ha-1 of K2O. The mean P, Ca and S contents were 1.6, 17.89 and 1.61 g kg-1, respectively, and the content of Mg2 + decreased from 5.62 to 2.74 g kg-1 at the dose of 0 and 160 kg ha-1 of K2O, respectively. The B, Mn and Fe contents decreased from 136.5 to 100.0, 346.24 to 248, and from 142.06 to 97.35 mg kg-1 at the dose of 0 and 160 kg ha-1 of K2O, respectively. The mean Cu and Zn contents were 3.81 and 40,54 mg kg-1, respectively, at the K2O doses. The nutrient content determined in the leaves of M. dubia were adequate for the development of the species in the first year of cultivation, presenting the following decreasing order: N> Ca> K> Mg> P = S> Mn> B> Fe > Zn> Cu.

RESUMO A identificação da prevalência de déficit cognitivo, e fatores associados, é importante, dadas as implicações significativas para as políticas públicas e planejamento em saúde. Objetivo: Determinar a prevalência de CCF e fatores associados em idosos de uma área urbana brasileira. Métodos: Estudo transversal envolvendo 461 idosos residentes em uma área urbana de Fortaleza, Ceará. Foi aplicado um questionário socioeconômico e de saúde e realizou-se avaliação cognitiva através de três testes de rastreio: Miniexame do Estado Mental (MEEM), FV (Fluência Verbal) e TR (Teste do Relógio). A avaliação da capacidade funcional foi feita por um questionário de 21 atividades da vida diária. Comprometimento cognitivo foi definido pelo comprometimento no MEEM ajustado para escolaridade. Comprometimento funcional foi definido pela incapacidade para mais de 4 AVDs. Resultados: A prevalência de CCF foi de 13,64% (IC 95%: 10,33-16,64%). CCF foi proporcionalmente associado à idade: razão de chances (RC) 2,24 (IC95%: 1,04-4,79) para 70 a 79 anos e RC 8,27 (IC 95%: 4,27-16,4) para 80 a 100 anos. CCF apresentou associação significante com doenças autorreferidas: hipertensão arterial sistêmica apresentou RC 2,06 (IC 95%: 1,17-3,65), acidente vascular cerebral de 2,88 (IC 95%: 1,66-5,00) e infarto agudo do miocárdio de 2,94(IC 95%: 1,59-5,42). A ocorrência de CCF correlacionou-se com maior número de medicamentos usados. Conclusão: O CCF é condição comum entre os idosos no Brasil e sua ocorrência está associada à idade, ao número de fármacos utilizados e às morbidades vasculares.

ABSTRACT The identification of the prevalence of cognitive impairment and associated factors among older adults is important in countries facing rapid demographic transition, given the significant implications for public policy and health planning. Objective: To determine the prevalence of functional cognitive impairment (FCI) and associated factors in Brazilian community-dwelling older adults. Methods: A cross-sectional study involving 461 elderly subjects residing in Fortaleza city, Ceará was conducted. Cognitive assessment was performed using three tests: the MMSE (Mini-Mental State Examination), VF (Verbal Fluency) and CT (Clock Test). The functional capacity evaluation was based on a survey of 21 basic and instrumental activities of daily living (ADLs). Cognitive impairment was defined by MMSE cut-off points adjusted for literacy. Functional impairment was defined as dependency to carry out more than four ADLs. Results: The prevalence of FCI was 13.64% (95% CI: 10.33 to 16.64%). FCI was proportionally associated with age with OR=2.24 (95% CI: 1.04 to 4.79) for individuals aged 70 to 79 years and OR=8.27 (95 % CI: 4.27 to 16.4) for those aged 80 to 100 years. FCI was associated with self-reported diseases including hypertension OR=2.06 (95% CI: 1.17 to 3.65), stroke OR=2.88 (95% CI: 1.66 to 5.00) and acute myocardial infarction OR=2.94 (95% CI: 1.59 to 5.42). The occurrence of FCI was proportionally correlated with the number of drugs used. Conclusion: Functional cognitive impairment is a prevalent condition in Brazilian community-dwelling older adults and its occurrence is associated with age, number of drugs used, and vascular morbidities.

Resumo Fundamento: Pacientes submetidos à ressincronização cardíaca podem evoluir com padrões de resposta acima do esperado, com normalização dos parâmetros clínicos e ecocardiográficos. Objetivo: Analisar as características clínicas e ecocardiográficas desta população de super-respondedores, comparando-as com os demais pacientes submetidos à terapia de ressincronização cardíaca. Métodos: Estudo de coorte observacional, prospectivo, envolvendo 146 pacientes, consecutivamente submetidos a implantes de ressincronizador cardíaco. Para comparação das variáveis, foram realizados o teste exato de Fisher e o teste de Mann-Whitney. Foram considerados super-respondedores os pacientes com fração de ejeção > 50 % e classe funcional I/II (New York Heart Association) após 6 meses da terapia de ressincronização cardíaca. Resultados: A idade média foi de 64,8 ± 11,1 anos, sendo 69,8% do sexo masculino, com mediana da fração de ejeção de 29%, sendo 71,5% com bloqueio de ramo esquerdo, 12% com bloqueio de ramo direito associado a bloqueios divisionais; 16,3% com marca-passo cardíaco definitivo, 29,3% com miocardiopatia isquêmica, 59,4% com miocardiopatia dilatada e 11,2% com miocardiopatia chagásica. Foram observados 24 (16,4%) super-respondedores, sendo que 13 (8,9%) apresentaram normalização da fração de ejeção, dos diâmetros diastólicos do ventrículo esquerdo e da classe funcional. Quando comparados com os pacientes não super-respondedores, em relação às características pré-implante, os super-respondedores apresentaram-se mais no sexo feminino (58,3% vs. 22,8%; p = 0,002), maior índice de massa corporal (26,8 vs. 25,5; p = 0,013), maior fração de ejeção basal (31,0 vs. 26,9; p = 0,0003) e menores diâmetros diastólicos do ventrículo esquerdo (65,9 mm vs. 72,6 mm; p = 0,0032). Dez pacientes (41,6% dos super-respondedores) com bloqueio de ramo direito e bloqueio divisional evoluíram como super-respondedores, entretanto apenas um paciente com doença de Chagas e apenas na primeira avaliação. Conclusões: Os super-respondedores apresentaram cardiopatia de base menos avançada e sem diferenças em relação ao tipo de distúrbio de condução basal. Pacientes com bloqueio de ramo direito e bloqueio divisional, mas sem cardiopatia chagásica podem também evoluir como super-respondedores.

Abstract Background: Patients submitted to cardiac resynchronization may develop response patterns that are higher than expected, with normalization of clinical and echocardiographic parameters. Objective: To analyze the clinical and echocardiographic characteristics of this population of super-responders, comparing them with the other patients submitted to cardiac resynchronization therapy. Methods: A prospective, observational cohort study involving 146 patients consecutively submitted to cardiac resynchronization implants. Fisher's exact test and Mann-Whitney test were performed to compare the variables. Patients with ejection fraction > 50% and functional class I/II (New York Heart Association) were considered super-responders after 6 months of cardiac resynchronization therapy. Results: Mean age was 64.8 ± 11.1 years, with 69.8% of males, with a median ejection fraction of 29%, 71.5% with left bundle-branch block, 12% with right bundle-branch block associated with hemiblocks; 16.3% wearing a definitive cardiac pacemaker, 29.3% with ischemic cardiomyopathy, 59.4% with dilated cardiomyopathy, and 11.2% with Chagasic cardiomyopathy. Twenty-four (16.4%) super-responders were observed, and 13 (8.9%) showed normalization of the ejection fraction, left ventricular diastolic diameters and functional class. When compared to the non-super-responder patients, in relation to the pre-implantation characteristics, the super-responders were more often females (58.3% vs. 22.8%, p = 0.002), had higher body mass index (26.8 vs. 25.5, p = 0.013), higher baseline ejection fraction (31.0 vs. 26.9, p = 0.0003), and lower left ventricular diastolic diameters (65.9 mm vs. 72.6 mm, p = 0.0032). Ten patients (41.6% of super-responders) with right bundle-branch block and hemiblock progressed to super-responders, although there was only one patient with Chagas' disease among them, and only at the first assessment. Conclusions: Super-responders had less advanced heart disease at baseline and no differences regarding the type of conduction disorder at baseline. Patients with right bundle-branch block and hemiblock, but without Chagasic heart disease may also progress as super-responders.

OBJECTIVES: Post-transplantation hypertension is prevalent and is associated with increased cardiovascular morbidity and subsequent graft dysfunction. The present study aimed to identify the factors associated with arterial stiffness as measured by the ambulatory arterial stiffness index. METHODS: The current study used a prospective, observational, analytical design to evaluate a group of adult heart transplantation patients. Arterial stiffness was obtained by monitoring ambulatory blood pressure and using the ambulatory arterial stiffness index as the surrogate outcome. Multivariate logistic regression analyses were performed to control confounding. RESULTS: In a group of 85 adult heart transplantation patients, hypertension was independently associated with arterial stiffness (OR 4.98, CI 95% 1.06-23.4) as well as systolic and diastolic blood pressure averages and nighttime descent. CONCLUSIONS: Measurement of ambulatory arterial stiffness index is a new, non-invasive method that is easy to perform, may contribute to better defining arterial stiffness prognosis and is associated with hypertension.

Introduction: the H. pylori infection affects more than half of humanity, being a public health problem. Its prevalence is significantly higher in developing countries like Brazil. It has been suggested that H. pylori infection may influence the intake and caloric homeostasis. Purpose: to compare nutritional status and food intake of patients attended by National Health System, with and without H. pylori infection. Methods: 140 patients were assessed. They performed upper gastrointestinal endoscopy to investigate the presence of H. pylori. Body weight and height of the patients were measured. Food intake was investigated through two 24-hour recalls, with data transformed in grams and analyzed in DietWin Professional 2.0 software. The findings were compared using the chi-square test or Student's t-test, adopting p < 0.05 as significance level. Results: there was predominance of patients with excess weight for both Hp - (60.3%) and Hp + (67.7%), with no difference between them. Food intake of assessed groups was similar. Conclusion: no differences were found in nutritional status and food intake between the two studied groups.

Introducción: la infección por H. pylori afecta a más de la mitad de la humanidad, siendo un problema de salud pública. Su prevalencia es significativamente mayor en los países en desarrollo, como Brasil. Se ha sugerido que la infección por H. pylori puede influir en la ingesta y la homeostasis calórica. Propósito: comparar el estado nutricional y la ingesta de alimentos de los pacientes incluidos en el Sistema Nacional de Salud, con y sin infección por H. pylori. Métodos: se evaluarón 140 pacientes. Realizaron la endoscopia digestiva alta para investigar la presencia de H. pylori. Se midieron el peso corporal y la altura de los pacientes. La ingesta de alimentos se investigó a través de dos recordatorios de 24 horas, con los dados transformados en gramos y analizados en el software DietWin Professional 2.0. Los resultados se compararon mediante la prueba de chi-cuadrado o la prueba t de Student. Se adoptó de p < 0,05 como nivel de significación. Resultados: hubo predominio de pacientes con exceso de peso tanto para Hp - (60,3%) como Hp + (67,7%), sin diferencias entre ellos. La ingesta de alimentos de los grupos evaluados fue similar. Conclusiones: no hubo diferencias en el estado nutricional y la ingesta de alimentos entre los dos grupos.

O modelo tradicional de controle da dengue no Brasil elegeu como um dos seus principais eixos estratégicos a participação popular. Na prática, essa estratégia tem se mostrado incapaz de promover o envolvimento e a mudança de comportamento da população, considerados essenciais para o controle dessa endemia. No presente estudo, realizou-se uma revisão integrativa de artigos publicados na literatura científica sobre conhecimentos, atitudes e práticas da população acerca da doença. Esse método foi escolhido porque permite reunir e sintetizar resultados de pesquisas sobre o tema selecionado, contribuindo para o aprofundamento do conhecimento em relação ao assunto investigado. Conclui-se que há um distanciamento entre as ações governamentais e a realidade da população, a sugerir a necessidade de implantação de uma política de prevenção e controle menos verticalizada, na qual os conhecimentos sociais possam nortear as estratégias de controle da doença de acordo com os interesses, necessidades, desejos e visões de mundo da comunidade. Nesta perspectiva, a população deixa de ser mera espectadora e dependente de ações previamente definidas para ocupar posição privilegiada nesse processo, assegurando a efetividade e a sustentabilidade das ações do programa.

The traditional model for dengue control in Brazil has established that community participation is one of its main strategic pillars. In practice, this strategy has been unable to promote the involvement and behaviour change of the population, which are considered essential to control this endemic disease. In the present study, we carried out an integrative review of articles published in the scientific literature on knowledge, attitudes and practices of the population about the disease. This method was chosen because it allows gathering and synthesizing research findings on the selected theme, thus contributing to enhance knowledge on the investigated subject. We conclude that there is a gap between the government's actions and the population's reality, which suggests the need to implement a less vertical prevention and control policy, in which social knowledge can guide strategies for disease control in accordance with the community's interests, needs, desires and worldviews. In this perspective, the population ceases to be a mere spectator, dependent on previously defined actions, and occupies a prominent position in the process, ensuring the effectiveness and sustainability of the program's activities.

O modelo tradicional de controle da dengue no Brasil elegeu como um dos seus principais eixos estratégicos a participação popular. Na prática, essa estratégia tem se mostrado incapaz de promover o envolvimento e a mudança de comportamento da população, considerados essenciais para o controle dessa endemia. No presente estudo, realizou-se uma revisão integrativa de artigos publicados na literatura científica sobre conhecimentos, atitudes e práticas da população acerca da doença. Esse método foi escolhido porque permite reunir e sintetizar resultados de pesquisas sobre o tema selecionado, contribuindo para o aprofundamento do conhecimento em relação ao assunto investigado. Conclui-se que há um distanciamento entre as ações governamentais e a realidade da população, a sugerir a necessidade de implantação de uma política de prevenção e controle menos verticalizada, na qual os conhecimentos sociais possam nortear as estratégias de controle da doença de acordo com os interesses, necessidades, desejos e visões de mundo da comunidade. Nesta perspectiva, a população deixa de ser mera espectadora e dependente de ações previamente definidas para ocupar posição privilegiada nesse processo, assegurando a efetividade e a sustentabilidade das ações do programa.

The traditional model for dengue control in Brazil has established that community participation is one of its main strategic pillars. In practice, this strategy has been unable to promote the involvement and behaviour change of the population, which are considered essential to control this endemic disease. In the present study, we carried out an integrative review of articles published in the scientific literature on knowledge, attitudes and practices of the population about the disease. This method was chosen because it allows gathering and synthesizing research findings on the selected theme, thus contributing to enhance knowledge on the investigated subject. We conclude that there is a gap between the government's actions and the population's reality, which suggests the need to implement a less vertical prevention and control policy, in which social knowledge can guide strategies for disease control in accordance with the community's interests, needs, desires and worldviews. In this perspective, the population ceases to be a mere spectator, dependent on previously defined actions, and occupies a prominent position in the process, ensuring the effectiveness and sustainability of the program's activities.