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1.
Impact of transsexualizing process centers on self-medication of transgender individuals
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Moraes, Arthur Machado Geiger Dias de
; Souza, Caren Nariel Pereira Santos
; Marques, Luiza Taddeo
; Barcelos, João Fernando Nascimento de
; Oliveira, Felipe Barros
; Bispo, Rafaela Góes
; Santos, Rodrigo Gomes
; Santos, Ailton da Silva
; Faria Júnior, José Antônio Diniz
; Oliveira, Luciana Mattos Barros
.
ABSTRACT OBJECTIVE The transgender population in Brazil faces marginalization and difficulties in accessing education and health, leading many individuals to self-medicate. This study aimed to evaluate the impact of the implementation of Specialized Centers in the Transsexualizing Process (SCTP) on the use of cross-sex hormone therapy (CSHT) without medical prescription, as well as the level of education and mental health profile of these individuals. METHODS This is a cross-sectional study with data from physical and electronic medical records between September 2017 and February 2023 regarding the use of CSHT before and after the implementation of two SCTP in the state of Bahia, Brazil, in addition to data on education level, previous diagnosis of anxiety and depression of patients. RESULTS A total of 219 participants, 127 transgender men (TM) and 92 transgender women and travestis (TrTW), were assessed. A significant reduction in the prevalence of self-medication was observed in both TrTW (92.98% before and 51.43% after, p<0.001), and TM (47.17% before and 25.67% after, p = 0.010) with the implementation of SCTP. Transgender individuals who used CSHT before accessing the service were found to have a lower prevalence of depression. Self-medication was not significantly associated with education or anxiety in our sample. CONCLUSION The results indicate the need for the expansion of SCTP, as they were associated with lower rates of self-medication in the transgender population.
2.
Long COVID-19 and mnemonic effects: an integrative literature review COVID19 COVID 19 COVID-1 effects COVID1 1 COVID-
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Martins, Wóquiton Rodrigo Marques
; Cardoso, Tarcísio Viana
; Oliveira, Ana Lívia
; Fernandes, Guilherme Silva
; Fontes, Ione Fernanda Lemos
; Dantas, Jaqueline Gonçalves
; Miranda, Joyce de Souza
; Martins, Julio Emanuel
; Antunes, Lorenna Nascimento
; Leite, Tarcisio Gomes
.
3.
Diretrizes Brasileiras de Medidas da Pressão Arterial Dentro e Fora do Consultório – 2023 202 20 2
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Feitosa, Audes Diogenes de Magalhães
; Barroso, Weimar Kunz Sebba
; Mion Junior, Decio
; Nobre, Fernando
; Mota-Gomes, Marco Antonio
; Jardim, Paulo Cesar Brandão Veiga
; Amodeo, Celso
; Oliveira, Adriana Camargo
; Alessi, Alexandre
; Sousa, Ana Luiza Lima
; Brandão, Andréa Araujo
; Pio-Abreu, Andrea
; Sposito, Andrei C.
; Pierin, Angela Maria Geraldo
; Paiva, Annelise Machado Gomes de
; Spinelli, Antonio Carlos de Souza
; Machado, Carlos Alberto
; Poli-de-Figueiredo, Carlos Eduardo
; Rodrigues, Cibele Isaac Saad
; Forjaz, Claudia Lucia de Moraes
; Sampaio, Diogo Pereira Santos
; Barbosa, Eduardo Costa Duarte
; Freitas, Elizabete Viana de
; Cestario, Elizabeth do Espirito Santo
; Muxfeldt, Elizabeth Silaid
; Lima Júnior, Emilton
; Campana, Erika Maria Gonçalves
; Feitosa, Fabiana Gomes Aragão Magalhães
; Consolim-Colombo, Fernanda Marciano
; Almeida, Fernando Antônio de
; Silva, Giovanio Vieira da
; Moreno Júnior, Heitor
; Finimundi, Helius Carlos
; Guimarães, Isabel Cristina Britto
; Gemelli, João Roberto
; Barreto-Filho, José Augusto Soares
; Vilela-Martin, José Fernando
; Ribeiro, José Marcio
; Yugar-Toledo, Juan Carlos
; Magalhães, Lucélia Batista Neves Cunha
; Drager, Luciano F.
; Bortolotto, Luiz Aparecido
; Alves, Marco Antonio de Melo
; Malachias, Marcus Vinícius Bolívar
; Neves, Mario Fritsch Toros
; Santos, Mayara Cedrim
; Dinamarco, Nelson
; Moreira Filho, Osni
; Passarelli Júnior, Oswaldo
; Vitorino, Priscila Valverde de Oliveira
; Miranda, Roberto Dischinger
; Bezerra, Rodrigo
; Pedrosa, Rodrigo Pinto
; Paula, Rogerio Baumgratz de
; Okawa, Rogério Toshiro Passos
; Póvoa, Rui Manuel dos Santos
; Fuchs, Sandra C.
; Lima, Sandro Gonçalves de
; Inuzuka, Sayuri
; Ferreira-Filho, Sebastião Rodrigues
; Fillho, Silvio Hock de Paffer
; Jardim, Thiago de Souza Veiga
; Guimarães Neto, Vanildo da Silva
; Koch, Vera Hermina Kalika
; Gusmão, Waléria Dantas Pereira
; Oigman, Wille
; Nadruz Junior, Wilson
.
4.
Bacterial community dominance in a sewage-driven eutrophic coastal lagoon by next generation sequencing: initial findings sewagedriven sewage driven sequencing
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Leite, Analy Machado de Oliveira
; Molisani, Mauricio Mussi
; Oliveira, Renan Monte de
; Pontes, Paula Veronesi Marinho
; Fonseca, Rodrigo Nunes da
; Menezes, Jackson de Souza
; Gomes Neto, Lupis Ribeiro
; Esteves, Francisco Assis
.
Resumo: Este estudo investiga a dominância bacteriana em uma das mais estudadas lagoas costeiras eutróficas contaminadas por esgoto, a Lagoa Imboassica em Macaé (RJ), Brasil, utilizando sequenciamento massivo do gene codificador do RNAr 16S. Foram coletadas amostras de água de três locais na lagoa. O DNA microbiano total foi extraído e a região V3-V4 do gene RNAr 16S foi amplificada e sequenciada na plataforma Illumina MiSeq. Um total de 744.879 sequências parciais do gene RNAr 16S foram agrupadas, revelando a ausência de uma dominância bacteriana única na lagoa costeira eutrófica influenciada por esgoto. Os filos predominantes detectados na lagoa foram Cyanobacteria (27,8%), Proteobacteria (23,7%) e Actinobacteria (14,6%). Proteobacteria emergiu como o filo mais abundante no local da lagoa impactado pelo esgoto, enquanto Cyanobacteria dominou os outros dois locais de amostragem. A família de maior prevalência encontrada foi a Synechococcaceae, sendo representada pelo gênero Synechococcus. Famílias do filo Cyanobacteria consideradas potencialmente tóxicas representaram menos de 1% do total de famílias. A região da lagoa impactada pelo esgoto exibiu maior diversidade e riqueza bacteriana. A dominância de comunidades bacterianas associadas ao esgoto bruto, como membros da família Enterobacteriaceae, não foi confirmada, a qual representou somente 0,75% das famílias no local mais afetado. Este estudo apresenta a análise inicial da comunidade bacteriana na Lagoa Imboassica e sugere que a dominância responde a eutrofização e descarga de esgoto. Resumo RJ, RJ , (RJ) Brasil S V3V4 VV V3 V4 V V3-V MiSeq 744879 744 879 744.87 agrupadas 27,8%, 278 27,8% 27 8 (27,8%) 23,7% 237 23 7 (23,7% 14,6%. 146 14,6% . 14 6 (14,6%) amostragem Synechococcaceae Synechococcus 1 bruto Enterobacteriaceae confirmada 075 0 75 0,75 afetado (RJ V3V 74487 74 87 744.8 27,8 2 (27,8% 23,7 (23,7 14,6 (14,6% 07 0,7 7448 744. 27, (27,8 23, (23, 14, (14,6 0, (27, (23 (14, (27 (2 (14 ( (1
Abstract: This study investigates the presence of bacterial dominance in one of the most studied sewage-driven eutrophic coastal lagoons, the Imboassica Lagoon in Macaé (RJ), Brazil, utilizing high-throughput sequencing of 16S rDNA. Water samples were collected from three sites within the lagoon. Total microbial DNA was extracted, and the V3-V4 region of the 16S rRNA gene was amplified and sequenced on the Illumina MiSeq platform. A total of 744,879 partial 16S rRNA sequences were clustered, revealing the absence of a single bacterial dominance in the sewage-driven eutrophic coastal lagoon. The prominent phyla detected in the lagoon were Cyanobacteria (27.8%), Proteobacteria (23.7%), and Actinobacteria (14.6%). Proteobacteria emerged as the most abundant phylum in the sewage-impacted lagoon site, whereas Cyanobacteria dominated the other two sampling sites. Among families, Synechococcaceae predominated with genus Synechococcus exhibited the highest prevalence. Families of potentially toxic Cyanobacteria represented less than 1% of the total families. The sewage-impacted lagoon section displayed greater bacterial diversity and richness. The dominance of bacterial communities associated with raw sewage, such as members of the Enterobacteriaceae family, was not confirmed, constituting only 0.75% of the families in the most affected site. This study presents the initial analysis of the bacterial community in the Imboassica Lagoon and suggests that dominance in the lagoon responds to the eutrophication and sewage discharge. Abstract sewagedriven driven lagoons RJ, RJ , (RJ) Brazil highthroughput high throughput S rDNA extracted V3V4 VV V3 V4 V V3-V platform 744879 744 879 744,87 clustered 27.8%, 278 27.8% 27 8 (27.8%) 23.7%, 237 23.7% 23 7 (23.7%) 14.6%. 146 14.6% . 14 6 (14.6%) sewageimpacted impacted site prevalence 1 richness family confirmed 075 0 75 0.75 discharge (RJ V3V 74487 74 87 744,8 27.8 2 (27.8% 23.7 (23.7% 14.6 (14.6% 07 0.7 7448 744, 27. (27.8 23. (23.7 14. (14.6 0. (27. (23. (14. (27 (23 (14 (2 (1 (
5.
Effect of ZrO2 paste, surface treatments, and storage on Weibull characteristics and resin bond strength to zirconia ZrO paste treatments
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Crispim, Anne Heloyse Teixeira
; Silva, Sarah Emille Gomes da
; Moreira, Fernanda Gurgel de Gois
; Silva, Bianca Cristina Dantas da
; Piva, Amanda Maria de Oliveira Dal
; May, Liliana Gressler
; Daudt, Natália de Freitas
; Souza, Rodrigo Othávio Assunção
.
Resumo O objetivo é avaliar o efeito de diferentes tratamentos superficiais e do envelhecimento na resistência ao cisalhamento da zircônia ultratranslúcida. Foram confeccionados 36 blocos de zircônia ultratranslúcida (7x7x2mm) e sinterizados. Em seguida, divididos em 12 grupos de acordo com o “tratamento de superfície” (C-Primer; Al-Jateamento com Al2O3+Primer; Si-Silicato+Primer; Gl -Glaze+HF+Primer; Z-Zirlink; Zp-Zirlink+Primer) e fatores de “armazenamento” (ST-com, 150 dias/37º e sem). Após o tratamento superficial, foram construídos cinco cilindros (Ø=2mm; h=2,0mm) de cimento resinoso (n=15) em cada bloco cerâmico; ao final foi realizado o ensaio de resistência ao cisalhamento (1mm/min, 50Kgf) e análise de falhas superficiais. Foram confeccionadas 60 amostras adicionais (2x2x2mm) para análises extras (rugosidade superficial, MEV e EDS). Os dados de resistência de união e rugosidade superficial foram avaliados estatisticamente por ANOVA (2 fatores/1fator), teste de Tukey (5%) e análise de Weibull, respectivamente. ANOVA (2 fatores) revelou que todos os fatores foram estatisticamente significativos para a resistência de união. Os grupos de silicatização (SiST: 30,47AMPa; Si: 29,21AMPa) apresentaram os maiores valores de resistência de união, independente do armazenamento (Tukey). Enquanto os grupos tratados com Zirlink (ZST: 2,76FMPa; Z: 5,27EFMPa) apresentaram os valores mais baixos, apenas semelhantes ao grupo GlST (5,14EFMPa). O módulo de Weibull (m) apresentou diferença estatística entre os grupos (p=0,000). A ANOVA (1 fator) revelou que o fator “tratamento superficial” (p=0,0000) foi estatisticamente significativo para rugosidade superficial. Portanto, a aplicação de Zirlink e do Glaze na zircônia pré-sinterizada não promoveu adesão eficiente da zircônia ultratranslúcida ao cimento resinoso, mesmo quando associada a primer contendo MDP. 3 7x7x2mm xxmm x mm (7x7x2mm sinterizados seguida 1 superfície CPrimer C Primer (C-Primer AlJateamento Al Jateamento Al2O3+Primer Al2O3Primer AlOPrimer Al2O3 SiSilicato+Primer SiSilicatoPrimer Si Silicato+Primer Silicato Si-Silicato+Primer Glaze+HF+Primer GlazeHFPrimer HF -Glaze+HF+Primer ZZirlink Z Z-Zirlink ZpZirlink+Primer ZpZirlinkPrimer Zp Zirlink+Primer Zp-Zirlink+Primer “armazenamento STcom, STcom ST com, (ST-com 15 dias37º diasº dias 37º º sem. sem . sem) Ø=2mm Ø2mm Ømm Ø 2mm (Ø=2mm h=2,0mm h20mm hmm h 2 0mm n=15 n15 n (n=15 cerâmico 1mm/min, 1mmmin mmmin 1mm min (1mm/min 50Kgf Kgf 6 2x2x2mm (2x2x2mm EDS. EDS EDS) ( fatores/1fator, fatores1fator fatoresfator fatores/1fator , 1fator fatores/1fator) 5% 5 (5% respectivamente SiST (SiST 30,47AMPa 3047AMPa AMPa 30 47AMPa 29,21AMPa 2921AMPa 29 21AMPa Tukey. (Tukey) ZST (ZST 2,76FMPa 276FMPa FMPa 76FMPa 5,27EFMPa 527EFMPa EFMPa 27EFMPa baixos 5,14EFMPa. 514EFMPa 5,14EFMPa 14EFMPa (5,14EFMPa) m (m p=0,000. p0000 p p=0,000 0 000 (p=0,000) p=0,0000 p00000 0000 (p=0,0000 Portanto présinterizada pré sinterizada MDP AlO Al2O SiSilicato SilicatoPrimer ZpZirlink ZirlinkPrimer n=1 n1 (n=1 1mm/min (5 (Tukey (5,14EFMPa p000 p=0,00 00 (p=0,000 n= (n= p00 p=0,0 (p=0,00 (n p0 p=0, (p=0,0 p=0 (p=0, p= (p=0 (p= (p
Abstract The objective is to evaluate the effect of different surface treatments and storage on the shear strength of ultratranslucent zirconia. 36 blocks of ultra-translucent zirconia were fabricated (7x7x2mm) and sintered. Then, divided into 12 groups according to the “surface treatment” (C -Primer; Al -Sandblasting with Al2O3 + Primer; Si -Silicate + Primer; Gl -Glaze + HF + Primer; Z -Zirlink; Zp -Zirlink + Primer) and “storage” factors (ST-with 150 days/37º and without). After surface treatment, five cylinders (Ø=2mm; h=2.0mm) of resin cement (n=15) were constructed in each ceramic block; at the end, the shear strength test was performed (1mm/min, 50Kgf), and analysis of surface failures. 60 additional samples (2x2x2mm) were made for extras analysis (surface roughness, MEV, and EDS). Bond strength and surface roughness data were statistically evaluated by ANOVA (2 factors/1 factor), Tukey test (5%), and Weibull analysis, respectively. ANOVA (2-way) revealed that all factors were statistically significant for bond strength. The silicatization groups (SiST: 30.47AMPa; Si: 29.21AMPa) showed the highest bond strength values, regardless of storage (Tukey's test). While the groups treated with Zirlink (ZST: 2.76FMPa; Z: 5.27EFMPa) showed the lowest values, just similar to the GlST group (5.14EFMPa). The Weibull modulus (m) showed a statistical difference between groups (p=0.000). ANOVA (1 factor) revealed that the "surface treatment" factor (p=0.0000) was statistically significant for surface roughness. Therefore, the application of Zirlink and Glaze on pre-sintered zirconia did not promote efficient adhesion of the ultratranslucent zirconia to the resin cement, even when associated with a primer containing MDP. 3 ultra translucent 7x7x2mm xxmm x mm (7x7x2mm sintered Then 1 treatment C Primer -Primer Sandblasting AlO O Al2O Silicate “storage STwith ST 15 days37º daysº days 37º º without. without . without) Ø=2mm Ø2mm Ømm Ø 2mm (Ø=2mm h=2.0mm h20mm hmm h 2 0mm n=15 n15 n (n=15 block end 1mm/min, 1mmmin mmmin 1mm min (1mm/min 50Kgf, 50Kgf Kgf , 50Kgf) failures 6 2x2x2mm (2x2x2mm MEV EDS. EDS EDS) ( factors1 factors/ factor, 5%, 5 5% (5%) respectively 2way way (2-way SiST (SiST 30.47AMPa 3047AMPa AMPa 30 47AMPa 29.21AMPa 2921AMPa 29 21AMPa values Tukeys s test. test) ZST (ZST 2.76FMPa 276FMPa FMPa 76FMPa 5.27EFMPa 527EFMPa EFMPa 27EFMPa 5.14EFMPa. 514EFMPa 5.14EFMPa 14EFMPa (5.14EFMPa) m (m p=0.000. p0000 p p=0.000 0 000 (p=0.000) p=0.0000 p00000 0000 (p=0.0000 Therefore presintered pre MDP n=1 n1 (n=1 1mm/min (5% (5.14EFMPa p000 p=0.00 00 (p=0.000 n= (n= (5 p00 p=0.0 (p=0.00 (n p0 p=0. (p=0.0 p=0 (p=0. p= (p=0 (p= (p
6.
Lung cancer screening in Brazil: recommendations from the Brazilian Society of Thoracic Surgery, Brazilian Thoracic Association, and Brazilian College of Radiology and Diagnostic Imaging Brazil Surgery Association
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Pereira, Luiz Fernando Ferreira
; Santos, Ricardo Sales dos
; Bonomi, Daniel Oliveira
; Franceschini, Juliana
; Santoro, Ilka Lopes
; Miotto, André
; Sousa, Thiago Lins Fagundes de
; Chate, Rodrigo Caruso
; Hochhegger, Bruno
; Gomes Neto, Artur
; Schneider, Airton
; Araújo Neto, César Augusto de
; Escuissato, Dante Luiz
; Prado, Gustavo Faibischew
; Costa-Silva, Luciana
; Zamboni, Mauro Musa
; Ghefter, Mario Claudio
; Corrêa, Paulo César Rodrigues Pinto
; Torres, Pedro Paulo Teixeira e Silva
; Mussi, Ricardo Kalaf
; Muglia, Valdair Francisco
; Godoy, Irma de
; Bernardo, Wanderley Marques
.
RESUMO O câncer de pulmão (CP) é uma das neoplasias mais comuns e letais no Brasil, e apenas 15% dos pacientes são diagnosticados nos estágios iniciais. O tabagismo persiste como o responsável por mais de 85% de todos os casos. O rastreamento do CP (RCP) por meio da TC de baixa dosagem de radiação (TCBD) reduz a mortalidade do CP em 20%, e, quando combinado com a cessação do tabagismo, essa redução chega a 38%. Na última década, diversos países adotaram o RCP como recomendação de saúde populacional. No Brasil, embora ainda incipiente, a discussão sobre o tema é cada vez mais ampla e necessária. Com o intuito de aumentar o conhecimento e estimular o debate sobre o RCP, a Sociedade Brasileira de Cirurgia Torácica, a Sociedade Brasileira de Pneumologia e Tisiologia e o Colégio Brasileiro de Radiologia e Diagnóstico por Imagem constituíram um painel de especialistas para elaborar as recomendações para o RCP. As recomendações aqui apresentadas foram baseadas em revisão narrativa da literatura, com ênfase em grandes estudos populacionais, em revisões sistemáticas e em recomendações de diretrizes internacionais, sendo construídas após ampla discussão pelo grupo de especialistas. Os temas revisados foram os seguintes: porque rastrear, considerações gerais sobre tabagismo, epidemiologia do CP, critérios de elegibilidade, achados incidentais, lesões granulomatosas, modelos probabilísticos, requisitos mínimos da TCBD, aquisições volumétricas, riscos do rastreamento, estrutura mínima e papel da equipe multidisciplinar, conduta segundo o Lung CT Screening Reporting and Data System (Lung-RADS), custos vs. benefícios e perspectivas do rastreamento. (CP Brasil 15 iniciais 85 casos (RCP TCBD (TCBD 20 20% 38 38% década populacional incipiente necessária Torácica literatura populacionais internacionais seguintes rastrear elegibilidade incidentais granulomatosas probabilísticos volumétricas multidisciplinar LungRADS, LungRADS RADS , (Lung-RADS) vs 1 8 2 3 (Lung-RADS
ABSTRACT Although lung cancer (LC) is one of the most common and lethal tumors, only 15% of patients are diagnosed at an early stage. Smoking is still responsible for more than 85% of cases. Lung cancer screening (LCS) with low-dose CT (LDCT) reduces LC-related mortality by 20%, and that reduction reaches 38% when LCS by LDCT is combined with smoking cessation. In the last decade, a number of countries have adopted population-based LCS as a public health recommendation. Albeit still incipient, discussion on this topic in Brazil is becoming increasingly broad and necessary. With the aim of increasing knowledge and stimulating debate on LCS, the Brazilian Society of Thoracic Surgery, the Brazilian Thoracic Association, and the Brazilian College of Radiology and Diagnostic Imaging convened a panel of experts to prepare recommendations for LCS in Brazil. The recommendations presented here were based on a narrative review of the literature, with an emphasis on large population-based studies, systematic reviews, and the recommendations of international guidelines, and were developed after extensive discussion by the panel of experts. The following topics were reviewed: reasons for screening; general considerations about smoking; epidemiology of LC; eligibility criteria; incidental findings; granulomatous lesions; probabilistic models; minimum requirements for LDCT; volumetric acquisition; risks of screening; minimum structure and role of the multidisciplinary team; practice according to the Lung CT Screening Reporting and Data System; costs versus benefits of screening; and future perspectives for LCS. LC (LC tumors 15 stage 85 cases (LCS lowdose low dose (LDCT LCrelated related 20 20% 38 cessation decade populationbased population recommendation incipient necessary Surgery Association literature studies reviews guidelines reviewed criteria findings lesions models acquisition team System 1 8 2 3
7.
Survival Analysis in Adult Heart Transplantation: Experience from a Brazilian Single Center Transplantation
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Ferraz, Diogo Luiz de Magalhães
; Cunha, Cristiano Berardo Carneiro da
; Figueira, Fernando Augusto Marinho dos Santos
; Silva, Igor Tiago Correia
; Monteiro, Verônica Soares
; Carneiro, Rodrigo Moreno Dias
; Castro, Bruna Gomes de
; Requião, Mariana Barreto
; Oliveira, Victor de França
; Silva, Patrícia Jaqueline Xavier da
; Tchaick, Rodrigo Mezzalira
; Furtado, Ana Flávia Paiva
; Silva Filha, Maria de Fátima Oliveira da
; Souza, Renato Correia Fernandes de
; Mello, Maria Julia Gonçalves de
; Gallindo, Rodrigo Melo
.
Brazilian Journal of Cardiovascular Surgery
- Journal Metrics
ABSTRACT Introduction: Heart transplantation is the gold standard for advanced heart failure treatment. This study examines the survival rates and risk factors for early mortality in adult heart transplant recipients at a Brazilian center. Methods: This retrospective cohort study involved 255 adult heart transplant patients from a single center in Brazil. Data were collected from medical records and databases including three defined periods (2012-2015, 2016-2019, and 2020-2022). Statistical analysis employed Kaplan-Meier survival curves, Cox proportional hazards analysis for 30-day mortality risk factors, and Log-rank tests. Results: The recipients were mostly male (74.9%), and the mean age was 46.6 years. Main causes of heart failure were idiopathic dilated cardiomyopathy (33.9%), Chagas cardiomyopathy (18%), and ischemic cardiomyopathy (14.3%). The study revealed an overall survival of 68.1% at one year, 58% at five years, and 40.8% at 10 years after heart transplantation. Survivalimproved significantly over time, combining the most recent periods (2016 to 2022) it was 73.2% in the first year and 63% in five years. The main risk factors for 30-day mortality were longer time on cardiopulmonary bypass, the initial period of transplants (2012 to 2015), older age of the donor, and nutritional status of the donor (overweight or obese). The main causes of death within 30 days post-transplant were infection and primary graft dysfunction. Conclusion: The survival analysis by period demonstrated that the increased surgical volume, coupled with the team’s experience and modifications to the immunosuppression protocol, contributed to the improved early and mid-term outcomes. Introduction treatment Methods 25 Brazil 20122015, 20122015 2012 2015, 2015 (2012-2015 20162019, 20162019 2016 2019, 2019 2016-2019 20202022. 20202022 2020 2022 . 2020-2022) KaplanMeier Kaplan Meier curves 30day day Logrank Log rank tests Results 74.9%, 749 74.9% , 74 9 (74.9%) 466 46 6 46. 33.9%, 339 33.9% 33 (33.9%) 18%, 18 18% (18%) 14.3%. 143 14.3% 14 3 (14.3%) 681 68 1 68.1 58 408 40 8 40.8 (201 732 73 2 73.2 63 bypass 2015) overweight obese. obese obese) posttransplant post dysfunction Conclusion volume teams team s protocol midterm mid term outcomes 2012201 201 (2012-201 2016201 2016-201 2020202 202 2020-2022 74.9 7 (74.9% 4 33.9 (33.9% (18% 14.3 (14.3% 68. 5 40. (20 73. 201220 20 (2012-20 201620 2016-20 202020 2020-202 74. (74.9 33. (33.9 (18 14. (14.3 (2 20122 (2012-2 20162 2016-2 20202 2020-20 (74. (33. (1 (14. ( (2012- 2016- 2020-2 (74 (33 (14 2020- (7 (3
8.
Impact of transsexualizing process centers on self-medication of transgender individuals selfmedication self medication
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Moraes, Arthur Machado Geiger Dias de
; Souza, Caren Nariel Pereira Santos
; Marques, Luiza Taddeo
; Barcelos, João Fernando Nascimento de
; Oliveira, Felipe Barros
; Bispo, Rafaela Góes
; Santos, Rodrigo Gomes
; Santos, Ailton da Silva
; Faria Júnior, José Antônio Diniz
; Oliveira, Luciana Mattos Barros
.
ABSTRACT OBJECTIVE The transgender population in Brazil faces marginalization and difficulties in accessing education and health, leading many individuals to self-medicate. This study aimed to evaluate the impact of the implementation of Specialized Centers in the Transsexualizing Process (SCTP) on the use of cross-sex hormone therapy (CSHT) without medical prescription, as well as the level of education and mental health profile of these individuals. METHODS This is a cross-sectional study with data from physical and electronic medical records between September 2017 and February 2023 regarding the use of CSHT before and after the implementation of two SCTP in the state of Bahia, Brazil, in addition to data on education level, previous diagnosis of anxiety and depression of patients. RESULTS A total of 219 participants, 127 transgender men (TM) and 92 transgender women and travestis (TrTW), were assessed. A significant reduction in the prevalence of self-medication was observed in both TrTW (92.98% before and 51.43% after, p<0.001), and TM (47.17% before and 25.67% after, p = 0.010) with the implementation of SCTP. Transgender individuals who used CSHT before accessing the service were found to have a lower prevalence of depression. Self-medication was not significantly associated with education or anxiety in our sample. CONCLUSION The results indicate the need for the expansion of SCTP, as they were associated with lower rates of self-medication in the transgender population. selfmedicate. selfmedicate self medicate. medicate self-medicate (SCTP crosssex cross sex (CSHT prescription crosssectional sectional 201 202 Bahia patients 21 participants 12 (TM 9 TrTW, , (TrTW) assessed selfmedication medication 92.98% 9298 98 (92.98 5143 51 43 51.43 p<0.001, p0001 p<0.001 0 001 p<0.001) 47.17% 4717 47 17 (47.17 2567 25 67 25.67 0.010 0010 010 Selfmedication Self sample 20 2 1 (TrTW 92.98 929 (92.9 514 5 4 51.4 p000 p<0.00 00 47.17 471 (47.1 256 6 25.6 0.01 01 92.9 (92. 51. p00 p<0.0 47.1 (47. 25. 0.0 92. (92 p0 p<0. 47. (47 0. (9 p<0 (4 ( p<
9.
Analysis of variables that can interfere with clinical outcomes of patients presented with vocal or swallowing complaints
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Dornelas, Rodrigo
; Silva, Kelly da
; Brendim, Mariana Pinheiro
; Silveira, Livia Oliveira
; Barretto, Renata Barros Sá
; Fontes, Gabriela Eduarda Nicásio Gomes
; Santos, Beatriz Ferreira dos
; Ribeiro, Vanessa Veis
; Guedes-Granzotti, Raphaela Barroso
.
RESUMO Objetivo: analisar as variáveis sociodemográficas que podem interferir no desfecho de casos clínicos de pacientes com queixas de voz ou deglutição. Métodos: estudo observacional, transversal, descritivo e retrospectivo. Foram analisados os prontuários de pessoas maiores de 18 anos atendidas na Clínica de Voz do Serviço de Fonoaudiologia do Hospital Universitário do Rio de Janeiro de 2010 a 2018. Foram incluídos 81 prontuários, sendo 47 de participantes do gênero feminino e 34 do masculino. Os pacientes foram divididos quanto a três tipos de desfecho: alta, desligamento e abandono. As variáveis sociodemográficas estudadas foram gênero, estado civil, escolaridade, renda, ser ou não profissional da voz e queixa principal. Para análise dos resultados, foram contabilizadas as frequências relativa e absoluta e, para análise inferencial, foi utilizado o teste Qui-Quadrado de Pearson (nível de significância de 5%). Resultados: as variáveis sociodemográficas não estiveram significantemente associadas aos desfechos estudados quando não se considerou o tipo de queixa (de voz ou de deglutição) de forma separada. Especificamente, observou-se uma frequência significativamente maior de pacientes com queixa de voz e que receberam alta fonoaudiológica (p=0,020). Nestes pacientes, houve associação significativa entre a frequência maior de pacientes que abandonaram a terapia e que possuíam renda de até um salário-mínimo (p=0,041). Não houve associações significativas nas pessoas com queixas de deglutição e as variáveis sociodemográfica estudadas. Conclusão: o desfecho mais frequente foi o abandono ao tratamento. Neste estudo, a baixa renda familiar esteve associada ao abandono do tratamento por pacientes com queixa de voz. Pacientes com queixas de deglutição apresentaram menor frequência de abandono ao tratamento e menos alta do que pacientes com queixas de voz. Objetivo Métodos observacional transversal retrospectivo 1 201 2018 8 4 3 masculino civil escolaridade principal resultados inferencial QuiQuadrado Qui Quadrado nível 5%. 5 5% . 5%) Resultados separada Especificamente observouse observou p=0,020. p0020 p p=0,020 0 020 (p=0,020) saláriomínimo salário mínimo p=0,041. p0041 p=0,041 041 (p=0,041) Conclusão 20 p002 p=0,02 02 (p=0,020 p004 p=0,04 04 (p=0,041 2 p00 p=0,0 (p=0,02 (p=0,04 p0 p=0, (p=0,0 p=0 (p=0, p= (p=0 (p= (p
ABSTRACT Purpose: to analyze sociodemographic variables that may interfere with the clinical outcome of patients with voice or swallowing complaints. Methods: a descriptive, retrospective, cross-sectional, observational study in which the medical records of patients above 18 years old treated at the Voice Clinic of the Speech-Language-Hearing Service of the Rio de Janeiro University Hospital between 2010 and 2018, were analyzed, including 81 medical records - 47 from females and 34 from males. Patients were divided according to three types of outcomes, namely: discharge, dismissal, and abandonment. The sociodemographic variables were sex, marital status, education level, income, whether they were occupational voice users, and the main complaint. The relative and absolute frequencies were calculated to analyze the results, and the Pearson´s chi-square test was used for inferential analysis (significance level of 5%). Results: sociodemographic variables were not significantly associated with the outcomes when the type of complaint (voice or swallowing) was not considered, separately. The study found a significantly higher frequency of patients with voice complaints who were discharged from speech-language-hearing therapy (p = 0.020). The higher frequency of such patients who abandoned therapy was significantly associated with an income of up to one minimum wage (p = 0.041). People with swallowing complaints were not significantly associated with sociodemographic variables. Conclusion: the most frequent outcome was treatment abandonment. In this study, low family income was associated with treatment abandonment by patients with voice complaints. Patients with swallowing complaints had a lower frequency of treatment abandonment and discharge than patients with voice complaints. Purpose Methods descriptive retrospective crosssectional, crosssectional cross sectional, sectional cross-sectional 1 SpeechLanguageHearing Speech Language Hearing 201 2018 analyzed 8 4 3 males namely dismissal sex status users results Pearsons Pearson s chisquare chi square significance 5%. 5 5% . 5%) Results considered separately speechlanguagehearing speech language hearing p 0.020. 0020 0.020 0 020 0.020) 0.041. 0041 0.041 041 0.041) Conclusion 20 002 0.02 02 004 0.04 04 2 00 0.0 0.
10.
Safety of CoronaVac and ChAdOx1 vaccines against SARS-CoV-2 in patients with rheumatoid arthritis: data from the Brazilian multicentric study safer ChAdOx SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- arthritis SARS-CoV
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Cruz, Vitor Alves
; Guimarães, Camila
; Rêgo, Jozelia
; Machado, Ketty Lysie Libardi Lira
; Miyamoto, Samira Tatiyama
; Burian, Ana Paula Neves
; Dias, Laiza Hombre
; Pretti, Flavia Zon
; Batista, Danielle Cristina Filgueira Alves
; Mill, José Geraldo
; Oliveira, Yasmin Gurtler Pinheiro de
; Gadelha, Carolina Strauss Estevez
; Gouveia, Maria da Penha Gomes
; Moulin, Anna Carolina Simões
; Souza, Bárbara Oliveira
; Aguiar, Laura Gonçalves Rodrigues
; Vieira, Gabriel Smith Sobral
; Grillo, Luiza Lorenzoni
; Lima, Marina Deorce de
; Pasti, Laís Pizzol
; Surlo, Heitor Filipe
; Faé, Filipe
; Moulaz, Isac Ribeiro
; Macabú, Mariana de Oliveira
; Ribeiro, Priscila Dias Cardoso
; Magalhães, Vanessa de Oliveira
; Aguiar, Mariana Freitas de
; Biegelmeyer, Erika
; Peixoto;, Flávia Maria Matos Melo Campos
; Kayser, Cristiane
; Souza, Alexandre Wagner Silva de
; Castro, Charlles Heldan de Moura
; Ribeiro, Sandra Lúcia Euzébio
; Telles, Camila Maria Paiva França
; Bühring, Juliana
; Lima, Raquel Lima de
; Santos, Sérgio Henrique Oliveira Dos
; Dias, Samuel Elias Basualto
; Melo, Natália Seixas de
; Sanches, Rosely Holanda da Silva
; Boechat, Antonio Luiz
; Sartori, Natália Sarzi
; Hax, Vanessa
; Dória, Lucas Denardi
; Rezende, Rodrigo Poubel Vieira de
; Baptista, Katia Lino
; Fortes, Natália Rodrigues Querido
; Melo, Ana Karla Guedes de
; Melo, Tâmara Santos
; Vieira, Rejane Maria Rodrigues de Abreu
; Vieira, Adah Sophia Rodrigues
; Kakehasi, Adriana Maria
; Tavares, Anna Carolina Faria Moreira Gomes
; Landa, Aline Teixeira de
; Costa, Pollyana Vitoria Thomaz da
; Azevedo, Valderilio Feijó
; Martins-Filho, Olindo Assis
; Peruhype-Magalhães, Vanessa
; Pinheiro, Marcelo de Medeiros
; Monticielo, Odirlei André
; Reis-neto, Edgard Torres Dos
; Ferreira, Gilda Aparecida
; Souza, Viviane Angelina de
; Teixeira-Carvalho, Andréa
; Xavier, Ricardo Machado
; Sato, Emilia Inoue
; Valim, Valeria
; Pileggi, Gecilmara Salviato
; Silva, Nilzio Antonio da
.
Abstract Background Patients with immune-mediated rheumatic diseases (IMRDs) have been prioritized for COVID-19 vaccination to mitigate the infection severity risks. Patients with rheumatoid arthritis (RA) are at a high risk of severe COVID-19 outcomes, especially those under immunosuppression or with associated comorbidities. However, few studies have assessed the safety of the COVID-19 vaccine in patients with RA. Objective To evaluate the safety of vaccines against SARS-CoV-2 in patients with RA. Methods This data are from the study “Safety and Efficacy on COVID-19 Vaccine in Rheumatic Diseases,” a Brazilian multicentric prospective phase IV study to evaluate COVID-19 vaccine in IMRDs in Brazil. Adverse events (AEs) in patients with RA of all centers were assessed after two doses of ChAdOx1 (Oxford/AstraZeneca) or CoronaVac (Sinovac/Butantan). Stratification of postvaccination AEs was performed using a diary, filled out daily and returned at the end of 28 days for each dose. Results A total of 188 patients with RA were include, 90% female. CoronaVac was used in 109 patients and ChAdOx1 in 79. Only mild AEs were observed, mainly after the first dose. The most common AEs after the first dose were pain at the injection (46,7%), headache (39,4%), arthralgia (39,4%), myalgia (30,5%) and fatigue (26,6%), and ChAdOx1 had a higher frequency of pain at the injection (66% vs 32 %, p < 0.001) arthralgia (62% vs 22%, p < 0.001) and myalgia (45% vs 20%, p < 0.001) compared to CoronaVac. The more common AEs after the second dose were pain at the injection (37%), arthralgia (31%), myalgia (23%), headache (21%) and fatigue (18%). Arthralgia (41,4% vs 25%, p = 0.02) and pain at injection (51,4% vs 27%, p = 0.001) were more common with ChAdOx1. No serious AEs were related. With Regard to RA activity level, no significant difference was observed between the three time periods for both COVID-19 vaccines. Conclusion In the comparison between the two immunizers in patients with RA, local reactions and musculoskeletal symptoms were more frequent with ChAdOx1 than with CoronaVac, especially after the first dose. In summary, the AE occurred mainly after the first dose, and were mild, like previous data from others immunizing agents in patients with rheumatoid arthritis. Vaccination did not worsen the degree of disease activity. immunemediated immune mediated (IMRDs COVID19 COVID 19 COVID-1 risks (RA outcomes comorbidities However SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- Safety Diseases, Diseases Brazil (AEs ChAdOx Oxford/AstraZeneca OxfordAstraZeneca Oxford AstraZeneca (Oxford/AstraZeneca Sinovac/Butantan. SinovacButantan Sinovac/Butantan . Sinovac Butantan (Sinovac/Butantan) diary 18 include 90 female 10 79 46,7%, 467 46,7% , 46 7 (46,7%) 39,4%, 394 39,4% 39 4 (39,4%) 30,5% 305 30 5 (30,5% 26,6%, 266 26,6% 26 6 (26,6%) 66% 66 (66 3 % 0.001 0001 0 001 62% 62 (62 22 22% 45% 45 (45 20 20% 37%, 37 37% (37%) 31%, 31 31% (31%) 23%, 23 23% (23%) 21% 21 (21% 18%. 18% (18%) 41,4% 414 41 (41,4 25 25% 0.02 002 02 51,4% 514 51 (51,4 27 27% related level summary COVID1 1 COVID- SARS-CoV (Sinovac/Butantan 9 46,7 (46,7% 39,4 (39,4% 30,5 (30,5 26,6 (26,6% (6 0.00 000 00 (4 (37% (31% (23% (21 (18% 41,4 (41, 0.0 51,4 (51, 46, (46,7 39, (39,4 30, (30, 26, (26,6 ( (37 (31 (23 (2 (18 41, (41 0. 51, (51 (46, (39, (30 (26, (3 (1 (5 (46 (39 (26
11.
Brazilian physiotherapist anxiety and depression during the COVID-19 pandemic: a cross-sectional survey COVID19 COVID 19 COVID-1 pandemic crosssectional cross sectional COVID1 1 COVID-
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Capellini, Verena Kise
; Paro, Flavia Marini
; Vieira, Rodrigo Daros
; Wittmer, Veronica Lourenço
; Barbalho-Moulim, Marcela Cangussu
; Soares, Samanta Caroline Santos
; Oliveira, Christyne Gomes Toledo de
; Duarte, Halina
.
Resumo Este estudo investigou a prevalência e potenciais fatores de risco para ansiedade e depressão em fisioterapeutas durante a pandemia. Fisioterapeutas responderam a um questionário na web, incluindo: dados sociodemográficos, profissionais e clínicos; demandas psicossociais; e dois questionários validados para medir ansiedade e depressão. Regressão logística binária identificou fatores de risco para ansiedade e depressão por meio de odds ratio (OR) e intervalo de confiança de 95% (IC). Em 417 participantes houve alta prevalência de ansiedade (48,2%) e depressão (53%). Os fatores de risco para ansiedade foram: sexo feminino (OR 2,07; IC95% 1,01-4,24), piora nos padrões de sono (OR 3,78; IC95% 1,92-7,44), moderada (OR 2,24; IC95% 1,00-5,00) e extrema preocupação financeira (OR 3,47; IC95% 1,57-7,65) e extrema solidão (OR 3,47; IC95% 1,71-7,07). Os fatores de risco para depressão foram: sexo feminino (OR 2,16; IC95% 1,03-4,55), baixa renda familiar (OR 2,43; IC95% 1,21-4,89), piora nos padrões de sono (OR 5,97; IC95% 3,02-11,82), extrema preocupação financeira (OR 2,61; IC95% 1,15-5,94) e extrema solidão (OR 4,38; IC95% 2,00-9,63). Este estudo mostrou alta prevalência de ansiedade e depressão na população estudada e identificou fatores de risco para ambos. pandemia web incluindo sociodemográficos clínicos psicossociais OR 95 IC. IC . (IC) 41 48,2% 482 48 2 (48,2% 53%. 53 53% (53%) foram 2,07 207 07 IC95 1,014,24, 101424 1,01 4,24 , 1 01 4 24 1,01-4,24) 3,78 378 3 78 1,927,44, 192744 1,92 7,44 92 7 44 1,92-7,44) 2,24 224 1,005,00 100500 1,00 5,00 00 5 1,00-5,00 3,47 347 47 1,577,65 157765 1,57 7,65 57 65 1,57-7,65 1,717,07. 171707 1,71 7,07 71 1,71-7,07) 2,16 216 16 1,034,55, 103455 1,03 4,55 03 55 1,03-4,55) 2,43 243 43 1,214,89, 121489 1,21 4,89 21 89 1,21-4,89) 5,97 597 97 3,0211,82, 3021182 3,02 11,82 02 11 82 3,02-11,82) 2,61 261 61 1,155,94 115594 1,15 5,94 15 94 1,15-5,94 4,38 438 38 2,009,63. 200963 2,00 9,63 9 63 2,00-9,63) ambos (IC 48,2 (48,2 (53% 2,0 20 0 IC9 014 1,014,24 10142 101 1,0 424 4,2 1,01-4,24 3,7 37 927 1,927,44 19274 192 1,9 744 7,4 1,92-7,44 2,2 22 005 1,005,0 10050 100 500 5,0 1,00-5,0 3,4 34 577 1,577,6 15776 157 1,5 765 7,6 6 1,57-7,6 717 1,717,07 17170 171 1,7 707 7,0 1,71-7,07 2,1 034 1,034,55 10345 103 455 4,5 1,03-4,55 2,4 214 1,214,89 12148 121 1,2 489 4,8 8 1,21-4,89 5,9 59 0211 3,0211,82 302118 302 3,0 1182 11,8 3,02-11,82 2,6 26 155 1,155,9 11559 115 1,1 594 1,15-5,9 4,3 009 2,009,63 20096 200 963 9,6 2,00-9,63 48, (48, (53 2, 1,014,2 1014 10 1, 42 4, 1,01-4,2 3, 1,927,4 1927 19 74 7, 1,92-7,4 1,005, 1005 50 5, 1,00-5, 1,577, 1577 76 1,57-7, 1,717,0 1717 17 70 1,71-7,0 1,034,5 1034 45 1,03-4,5 1,214,8 1214 12 1,21-4,8 021 3,0211,8 30211 30 118 11, 3,02-11,8 1,155, 1155 1,15-5, 2,009,6 2009 96 9, 2,00-9,6 (48 (5 1,014, 1,01-4, 1,927, 1,92-7, 1,005 1,00-5 1,577 1,57-7 1,717, 1,71-7, 1,034, 1,03-4, 1,214, 1,21-4, 3,0211, 3021 3,02-11, 1,155 1,15-5 2,009, 2,00-9, (4 ( 1,014 1,01-4 1,927 1,92-7 1,00- 1,57- 1,717 1,71-7 1,034 1,03-4 1,214 1,21-4 3,0211 3,02-11 1,15- 2,009 2,00-9 1,01- 1,92- 1,71- 1,03- 1,21- 3,021 3,02-1 2,00- 3,02-
Abstract This study investigated the prevalence and the potential risk factors for anxiety and depression among physiotherapists during the pandemic. Physiotherapists answered a web-based questionnaire including 1) sociodemographic, professional and clinical information; 2) psychosocial demands; and 3) two validated questionnaires to measure anxiety and depression. Binary logistic regression identified the risk factors by means of odds ratio (OR) and 95% confidence interval (CI). In 417 participants, there was a high prevalence of anxiety (48.2%) and depression (53.0%). The risk factors for anxiety were female sex (OR 2.07; 95%CI 1.01-4.24), worsening in sleep patterns (OR 3.78; 95%CI 1.92-7.44), moderate (OR 2.24; 95%CI 1.00-5.00) and extreme concern about financial issues (OR 3.47; 95%CI 1.57-7.65), and extreme loneliness (OR 3.47; 95%CI 1.71-7.07). The risk factors for depression were female sex (OR 2.16; 95%CI 1.03-4.55), low family income (OR 2.43; 95%CI 1.21-4.89), worsening in sleep patterns (OR 5.97; 95%CI 3.02-11.82), extreme concern about financial issues (OR 2.61; 95%CI 1.15-5.94), and extreme loneliness (OR 4.38; 95%CI 2.00-9.63). This study found a high prevalence of anxiety and depression in the studied population and identified risk factors for both. pandemic webbased web based 1 sociodemographic information 2 demands 3 OR 95 CI. CI . (CI) 41 participants 48.2% 482 48 (48.2% 53.0%. 530 53.0% 53 0 (53.0%) 2.07 207 07 95CI 1.014.24, 101424 1.01 4.24 , 01 4 24 1.01-4.24) 3.78 378 78 1.927.44, 192744 1.92 7.44 92 7 44 1.92-7.44) 2.24 224 1.005.00 100500 1.00 5.00 00 5 1.00-5.00 3.47 347 47 1.577.65, 157765 1.57 7.65 57 65 1.57-7.65) 1.717.07. 171707 1.71 7.07 71 1.71-7.07) 2.16 216 16 1.034.55, 103455 1.03 4.55 03 55 1.03-4.55) 2.43 243 43 1.214.89, 121489 1.21 4.89 21 89 1.21-4.89) 5.97 597 97 3.0211.82, 3021182 3.02 11.82 02 11 82 3.02-11.82) 2.61 261 61 1.155.94, 115594 1.15 5.94 15 94 1.15-5.94) 4.38 438 38 2.009.63. 200963 2.00 9.63 9 63 2.00-9.63) both (CI 48.2 (48.2 53.0 (53.0% 2.0 20 014 1.014.24 10142 101 1.0 424 4.2 1.01-4.24 3.7 37 927 1.927.44 19274 192 1.9 744 7.4 1.92-7.44 2.2 22 005 1.005.0 10050 100 500 5.0 1.00-5.0 3.4 34 577 1.577.65 15776 157 1.5 765 7.6 6 1.57-7.65 717 1.717.07 17170 171 1.7 707 7.0 1.71-7.07 2.1 034 1.034.55 10345 103 455 4.5 1.03-4.55 2.4 214 1.214.89 12148 121 1.2 489 4.8 8 1.21-4.89 5.9 59 0211 3.0211.82 302118 302 3.0 1182 11.8 3.02-11.82 2.6 26 155 1.155.94 11559 115 1.1 594 1.15-5.94 4.3 009 2.009.63 20096 200 963 9.6 2.00-9.63 48. (48. 53. (53.0 2. 1.014.2 1014 10 1. 42 4. 1.01-4.2 3. 1.927.4 1927 19 74 7. 1.92-7.4 1.005. 1005 50 5. 1.00-5. 1.577.6 1577 76 1.57-7.6 1.717.0 1717 17 70 1.71-7.0 1.034.5 1034 45 1.03-4.5 1.214.8 1214 12 1.21-4.8 021 3.0211.8 30211 30 118 11. 3.02-11.8 1.155.9 1155 1.15-5.9 2.009.6 2009 96 9. 2.00-9.6 (48 (53. 1.014. 1.01-4. 1.927. 1.92-7. 1.005 1.00-5 1.577. 1.57-7. 1.717. 1.71-7. 1.034. 1.03-4. 1.214. 1.21-4. 3.0211. 3021 3.02-11. 1.155. 1.15-5. 2.009. 2.00-9. (4 (53 1.014 1.01-4 1.927 1.92-7 1.00- 1.577 1.57-7 1.717 1.71-7 1.034 1.03-4 1.214 1.21-4 3.0211 3.02-11 1.155 1.15-5 2.009 2.00-9 ( (5 1.01- 1.92- 1.57- 1.71- 1.03- 1.21- 3.021 3.02-1 1.15- 2.00- 3.02-
12.
Brazilian physiotherapist anxiety and depression during the COVID-19 pandemic: a cross-sectional survey
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Capellini, Verena Kise
; Paro, Flavia Marini
; Vieira, Rodrigo Daros
; Wittmer, Veronica Lourenço
; Barbalho-Moulim, Marcela Cangussu
; Soares, Samanta Caroline Santos
; Oliveira, Christyne Gomes Toledo de
; Duarte, Halina
.
Resumo Este estudo investigou a prevalência e potenciais fatores de risco para ansiedade e depressão em fisioterapeutas durante a pandemia. Fisioterapeutas responderam a um questionário na web, incluindo: dados sociodemográficos, profissionais e clínicos; demandas psicossociais; e dois questionários validados para medir ansiedade e depressão. Regressão logística binária identificou fatores de risco para ansiedade e depressão por meio de odds ratio (OR) e intervalo de confiança de 95% (IC). Em 417 participantes houve alta prevalência de ansiedade (48,2%) e depressão (53%). Os fatores de risco para ansiedade foram: sexo feminino (OR 2,07; IC95% 1,01-4,24), piora nos padrões de sono (OR 3,78; IC95% 1,92-7,44), moderada (OR 2,24; IC95% 1,00-5,00) e extrema preocupação financeira (OR 3,47; IC95% 1,57-7,65) e extrema solidão (OR 3,47; IC95% 1,71-7,07). Os fatores de risco para depressão foram: sexo feminino (OR 2,16; IC95% 1,03-4,55), baixa renda familiar (OR 2,43; IC95% 1,21-4,89), piora nos padrões de sono (OR 5,97; IC95% 3,02-11,82), extrema preocupação financeira (OR 2,61; IC95% 1,15-5,94) e extrema solidão (OR 4,38; IC95% 2,00-9,63). Este estudo mostrou alta prevalência de ansiedade e depressão na população estudada e identificou fatores de risco para ambos.
Abstract This study investigated the prevalence and the potential risk factors for anxiety and depression among physiotherapists during the pandemic. Physiotherapists answered a web-based questionnaire including 1) sociodemographic, professional and clinical information; 2) psychosocial demands; and 3) two validated questionnaires to measure anxiety and depression. Binary logistic regression identified the risk factors by means of odds ratio (OR) and 95% confidence interval (CI). In 417 participants, there was a high prevalence of anxiety (48.2%) and depression (53.0%). The risk factors for anxiety were female sex (OR 2.07; 95%CI 1.01-4.24), worsening in sleep patterns (OR 3.78; 95%CI 1.92-7.44), moderate (OR 2.24; 95%CI 1.00-5.00) and extreme concern about financial issues (OR 3.47; 95%CI 1.57-7.65), and extreme loneliness (OR 3.47; 95%CI 1.71-7.07). The risk factors for depression were female sex (OR 2.16; 95%CI 1.03-4.55), low family income (OR 2.43; 95%CI 1.21-4.89), worsening in sleep patterns (OR 5.97; 95%CI 3.02-11.82), extreme concern about financial issues (OR 2.61; 95%CI 1.15-5.94), and extreme loneliness (OR 4.38; 95%CI 2.00-9.63). This study found a high prevalence of anxiety and depression in the studied population and identified risk factors for both.
13.
[SciELO Preprints] - UNLOCKING SCIENCE DIPLOMACY’S HIDDEN POWER: THE ROLE OF SCIENCE DIPLOMACY IN THE NEGOTIATION OVER THE ALPART REFINERY IN JAMAICA
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This article delves into the relationship between Science Diplomacy (SD) and multilateral negotiations, with a specific case study focusing on aluminum production in Jamaica. It highlights the often indirect yet pivotal role of SD in shaping the outcomes of negotiations concerning energy and environmental issues. Although the concept of SD is not always directly at the negotiation table, SD practices act as a bridge between the scientific community and policymakers. The case study analyzes the influence of SD on negotiations related to alumina production in Jamaica, specifically the sale of the Alpart alumina refinery in 2016. It demonstrates how SD diverted negotiations from solely political and commercial considerations to technical discussions on environmental impacts. The crisis initially centered around a coal-based power plant and eventually extended to bauxite extraction, revealing the critical role of affordable energy in aluminum refining. Methodologically, our research design follows the traditional guidelines of a descriptive case study. We employed concepts extracted from both the theory of negotiations and science diplomacy. Leverage power and interests of key actors, including JISCO (Jinquan Iron and Steel Company), the Jamaican government, and the Jamaica Environment Trust (JET), are dissected. Ultimately, it underscores the influence of SD practices on the negotiations, shifting the focus towards environmental concerns and highlighting the importance of informed decision-making in international negotiations. JET played a pivotal role by illuminating the environmental hazards and by influencing the redefinition of power dynamics in the negotiations. Thus, this work exemplifies how SD can reshape negotiations and foster sustainable solutions to complex global challenges.
Este artigo explora a relação entre Diplomacia Científica (DC) e negociações multilaterais, com um estudo de caso específico centrado na produção de alumínio na Jamaica. Ele destaca o papel muitas vezes indireto, mas crucial, da DC na formação dos resultados de negociações relacionadas a questões energéticas e ambientais. Embora o conceito de DC nem sempre esteja diretamente na mesa de negociações, as práticas de DC atuam como uma ponte entre a comunidade científica e os formuladores de políticas. O estudo de caso analisa a influência da DC nas negociações relacionadas à produção de alumina na Jamaica, especificamente na venda da refinaria de alumina Alpart em 2016. Ele demonstra como a DC desviou as negociações de considerações puramente políticas e comerciais para discussões técnicas sobre impactos ambientais. A crise inicialmente girava em torno de uma usina de energia a carvão e acabou se estendendo à extração de bauxita, destacando o papel crítico da energia acessível na refinação de alumínio. Do ponto de vista metodológico, o estudo utiliza um quadro descritivo de estudo de caso, somado a conceitos de teoria das negociações, para explorar a dinâmica do impacto da DC nas barganhas. O poder de influência e os interesses dos principais atores, incluindo a JISCO (Jinquan Iron and Steel Company), o governo jamaicano e a Jamaica Environment Trust (JET), são dissecados. Em última análise, o artigo destaca a influência das práticas de DC nas negociações, desviando o foco para as preocupações ambientais e destacando a importância da tomada de decisões informadas em negociações internacionais. A JET desempenhou um papel fundamental ao iluminar os riscos ambientais e influenciar a redefinição das dinâmicas de poder nas negociações. Assim, este trabalho exemplifica como a DC pode remodelar negociações e promover soluções sustentáveis para desafios globais complexos.
14.
[SciELO Preprints] - Brazilian Guidelines for In-office and Out-of-office Blood Pressure Measurement – 2023
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Feitosa, Audes Diógenes de Magalhães
Barroso, Weimar Kunz Sebba
Mion Júnior, Décio
Nobre, Fernando
Mota-Gomes, Marco Antonio
Jardim, Paulo Cesar Brandão Veiga
Amodeo, Celso
Camargo, Adriana
Alessi, Alexandre
Sousa, Ana Luiza Lima
Brandão, Andréa Araujo
Pio-Abreu, Andrea
Sposito, Andrei Carvalho
Pierin, Angela Maria Geraldo
Paiva, Annelise Machado Gomes de
Spinelli, Antonio Carlos de Souza
Machado, Carlos Alberto
Poli-de-Figueiredo, Carlos Eduardo
Rodrigues, Cibele Isaac Saad
Forjaz, Cláudia Lúcia de Moraes
Sampaio, Diogo Pereira Santos
Barbosa, Eduardo Costa Duarte
Freitas, Elizabete Viana de
Cestário , Elizabeth do Espírito Santo
Muxfeldt, Elizabeth Silaid
Lima Júnior, Emilton
Campana, Erika Maria Gonçalves
Feitosa, Fabiana Gomes Aragão Magalhães
Consolim-Colombo, Fernanda Marciano
Almeida, Fernando Antônio de
Silva, Giovanio Vieira da
Moreno Júnior, Heitor
Finimundi, Helius Carlos
Guimarães, Isabel Cristina Britto
Gemelli, João Roberto
Barreto Filho, José Augusto Soares
Vilela-Martin, José Fernando
Ribeiro, José Marcio
Yugar-Toledo, Juan Carlos
Magalhães, Lucélia Batista Neves Cunha
Drager, Luciano Ferreira
Bortolotto, Luiz Aparecido
Alves, Marco Antonio de Melo
Malachias, Marcus Vinícius Bolívar
Neves, Mario Fritsch Toros
Santos, Mayara Cedrim
Dinamarco, Nelson
Moreira Filho, Osni
Passarelli Júnior, Oswaldo
Valverde de Oliveira Vitorino, Priscila Valverde de Oliveira
Miranda, Roberto Dischinger
Bezerra, Rodrigo
Pedrosa, Rodrigo Pinto
Paula, Rogério Baumgratz de
Okawa, Rogério Toshiro Passos
Póvoa, Rui Manuel dos Santos
Fuchs, Sandra C.
Inuzuka, Sayuri
Ferreira-Filho, Sebastião R.
Paffer Fillho, Silvio Hock de
Jardim, Thiago de Souza Veiga
Guimarães Neto, Vanildo da Silva
Koch, Vera Hermina
Gusmão, Waléria Dantas Pereira
Oigman, Wille
Nadruz, Wilson
Hypertension is one of the primary modifiable risk factors for morbidity and mortality worldwide, being a major risk factor for coronary artery disease, stroke, and kidney failure. Furthermore, it is highly prevalent, affecting more than one-third of the global population.
Blood pressure measurement is a MANDATORY procedure in any medical care setting and is carried out by various healthcare professionals. However, it is still commonly performed without the necessary technical care. Since the diagnosis relies on blood pressure measurement, it is clear how important it is to handle the techniques, methods, and equipment used in its execution with care.
It should be emphasized that once the diagnosis is made, all short-term, medium-term, and long-term investigations and treatments are based on the results of blood pressure measurement. Therefore, improper techniques and/or equipment can lead to incorrect diagnoses, either underestimating or overestimating values, resulting in inappropriate actions and significant health and economic losses for individuals and nations.
Once the correct diagnosis is made, as knowledge of the importance of proper treatment advances, with the adoption of more detailed normal values and careful treatment objectives towards achieving stricter blood pressure goals, the importance of precision in blood pressure measurement is also reinforced.
Blood pressure measurement (described below) is usually performed using the traditional method, the so-called casual or office measurement. Over time, alternatives have been added to it, through the use of semi-automatic or automatic devices by the patients themselves, in waiting rooms or outside the office, in their own homes, or in public spaces. A step further was taken with the use of semi-automatic devices equipped with memory that allow sequential measurements outside the office (ABPM; or HBPM) and other automatic devices that allow programmed measurements over longer periods (HBPM).
Some aspects of blood pressure measurement can interfere with obtaining reliable results and, consequently, cause harm in decision-making. These include the importance of using average values, the variation in blood pressure during the day, and short-term variability. These aspects have encouraged the performance of a greater number of measurements in various situations, and different guidelines have advocated the use of equipment that promotes these actions. Devices that perform HBPM or ABPM, which, in addition to allowing greater precision, when used together, detect white coat hypertension (WCH), masked hypertension (MH), sleep blood pressure alterations, and resistant hypertension (RHT) (defined in Chapter 2 of this guideline), are gaining more and more importance.
Taking these details into account, we must emphasize that information related to diagnosis, classification, and goal setting is still based on office blood pressure measurement, and for this reason, all attention must be given to the proper execution of this procedure.
La hipertensión arterial (HTA) es uno de los principales factores de riesgo modificables para la morbilidad y mortalidad en todo el mundo, siendo uno de los mayores factores de riesgo para la enfermedad de las arterias coronarias, el accidente cerebrovascular (ACV) y la insuficiencia renal. Además, es altamente prevalente y afecta a más de un tercio de la población mundial.
La medición de la presión arterial (PA) es un procedimiento OBLIGATORIO en cualquier atención médica o realizado por diferentes profesionales de la salud. Sin embargo, todavía se realiza comúnmente sin los cuidados técnicos necesarios. Dado que el diagnóstico se basa en la medición de la PA, es claro el cuidado que debe haber con las técnicas, los métodos y los equipos utilizados en su realización.
Debemos enfatizar que una vez realizado el diagnóstico, todas las investigaciones y tratamientos a corto, mediano y largo plazo se basan en los resultados de la medición de la PA. Por lo tanto, las técnicas y/o equipos inadecuados pueden llevar a diagnósticos incorrectos, subestimando o sobreestimando valores y resultando en conductas inadecuadas y pérdidas significativas para la salud y la economía de las personas y las naciones.
Una vez realizado el diagnóstico correcto, a medida que avanza el conocimiento sobre la importancia del tratamiento adecuado, con la adopción de valores de normalidad más detallados y objetivos de tratamiento más cuidadosos hacia metas de PA más estrictas, también se refuerza la importancia de la precisión en la medición de la PA.
La medición de la PA (descrita a continuación) generalmente se realiza mediante el método tradicional, la llamada medición casual o de consultorio. Con el tiempo, se han agregado alternativas a través del uso de dispositivos semiautomáticos o automáticos por parte del propio paciente, en salas de espera o fuera del consultorio, en su propia residencia o en espacios públicos. Se dio un paso más con el uso de dispositivos semiautomáticos equipados con memoria que permiten mediciones secuenciales fuera del consultorio (AMPA; o MRPA) y otros automáticos que permiten mediciones programadas durante períodos más largos (MAPA).
Algunos aspectos en la medición de la PA pueden interferir en la obtención de resultados confiables y, en consecuencia, causar daños en las decisiones a tomar. Estos incluyen la importancia de usar valores promedio, la variación de la PA durante el día y la variabilidad a corto plazo. Estos aspectos han alentado la realización de un mayor número de mediciones en diversas situaciones, y diferentes pautas han abogado por el uso de equipos que promuevan estas acciones. Los dispositivos que realizan MRPA o MAPA, que además de permitir una mayor precisión, cuando se usan juntos, detectan la hipertensión de bata blanca (HBB), la hipertensión enmascarada (HM), las alteraciones de la PA durante el sueño y la hipertensión resistente (HR) (definida en el Capítulo 2 de esta guía), están ganando cada vez más importancia.
Teniendo en cuenta estos detalles, debemos enfatizar que la información relacionada con el diagnóstico, la clasificación y el establecimiento de objetivos todavía se basa en la medición de la presión arterial en el consultorio, y por esta razón, se debe prestar toda la atención a la ejecución adecuada de este procedimiento.
A hipertensão arterial (HA) é um dos principais fatores de risco modificáveis para morbidade e mortalidade em todo o mundo, sendo um dos maiores fatores de risco para doença arterial coronária, acidente vascular cerebral (AVC) e insuficiência renal. Além disso, é altamente prevalente e atinge mais de um terço da população mundial.
A medida da PA é procedimento OBRIGATÓRIO em qualquer atendimento médico ou realizado por diferentes profissionais de saúde. Contudo, ainda é comumente realizada sem os cuidados técnicos necessários. Como o diagnóstico se baseia na medida da PA, fica claro o cuidado que deve haver com as técnicas, os métodos e os equipamentos utilizados na sua realização.
Deve-se reforçar que, feito o diagnóstico, toda a investigação e os tratamentos de curto, médio e longo prazos são feitos com base nos resultados da medida da PA. Assim, técnicas e/ou equipamentos inadequados podem levar a diagnósticos incorretos, tanto subestimando quanto superestimando valores e levando a condutas inadequadas e grandes prejuízos à saúde e à economia das pessoas e das nações.
Uma vez feito o diagnóstico correto, na medida em que avança o conhecimento da importância do tratamento adequado, com a adoção de valores de normalidade mais detalhados e com objetivos de tratamento mais cuidadosos no sentido do alcance de metas de PA mais rigorosas, fica também reforçada a importância da precisão na medida da PA.
A medida da PA (descrita a seguir) é habitualmente feita pelo método tradicional, a assim chamada medida casual ou de consultório. Ao longo do tempo, foram agregadas alternativas a ela, mediante o uso de equipamentos semiautomáticos ou automáticos pelo próprio paciente, nas salas de espera ou fora do consultório, em sua própria residência ou em espaços públicos. Um passo adiante foi dado com o uso de equipamentos semiautomáticos providos de memória que permitem medidas sequenciais fora do consultório (AMPA; ou MRPA) e outros automáticos que permitem medidas programadas por períodos mais prolongados (MAPA).
Alguns aspectos na medida da PA podem interferir na obtenção de resultados fidedignos e, consequentemente, causar prejuízo nas condutas a serem tomadas. Entre eles, estão: a importância de serem utilizados valores médios, a variação da PA durante o dia e a variabilidade a curto prazo. Esses aspectos têm estimulado a realização de maior número de medidas em diversas situações, e as diferentes diretrizes têm preconizado o uso de equipamentos que favoreçam essas ações. Ganham cada vez mais espaço os equipamentos que realizam MRPA ou MAPA, que, além de permitirem maior precisão, se empregados em conjunto, detectam a HA do avental branco (HAB), HA mascarada (HM), alterações da PA no sono e HA resistente (HAR) (definidos no Capítulo 2 desta diretriz).
Resguardados esses detalhes, devemos ressaltar que as informações relacionadas a diagnóstico, classificação e estabelecimento de metas ainda são baseadas na medida da PA de consultório e, por esse motivo, toda a atenção deve ser dada à realização desse procedimento.
15.
Composite resin reinforced with silk nanoparticles from Bombyx mori cocoon for dental applications
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Torres, Adriana da Silva
; Silveira, João Vinícios Wirbitzki da
; Torres, Moisés de Matos
; Araujo, Cintia Tereza Pimenta de
; Galo, Rodrigo
; Oliveira, Simone Gomes Dias de
.
Resumo O objetivo deste trabalho foi avaliar o desempenho mecânico da resina composta Z350 modificada com nanopartículas de seda Bombyx mori cocoons para aplicações odontológicas. Quatro grupos experimentais foram analisados: G0%) Resina Z350 apenas (grupo controle); G1%) Reforço com 1% de nanopartículas de seda; G3%) Reforço com 3% de nanopartículas de seda; e G5%) Reforço com 5% de nanopartículas de seda. Foi empregado microscopia eletrônica de varredura, espectroscopia de energia dispersiva de raios X, difração de raios X, teste de resistência à flexão de 3 pontos, teste de dureza Knoop e rugosidade superficial. Nos testes de resistência à flexão de 3 pontos o grupo controle apresentou melhores resultados G0% = 0.113 GPa (±0.024). O maior módulo de flexão foi demonstrado pelos grupos G3% = 29.151GPa (±5.191) e G5% = 34.102 GPa (±7.94), que são estatisticamente semelhantes. O teste de microdureza Knoop mostrou diferença estatística apenas entre o grupo G3% entre os 80.78 superiores (± 3.00) e os 68.80 inferiores (±3.62). Não há diferença entre os grupos. O teste de rugosidade não apresentou diferença estatística entre os grupos. A incorporação de nanopartículas de seda reduziu a resistência à flexão da resina composta Z350. Os testes de rugosidade superficial e microdureza não apresentaram alterações em nenhum dos grupos estudados. Z Z35 odontológicas analisados G0 G controle) G1% G1 1 G3 G5 5 varredura X 0113 0 113 0.11 ±0.024. 0024 ±0.024 . 024 (±0.024) 29151GPa 29 151GPa ±5.191 5191 191 (±5.191 34102 34 102 34.10 ±7.94, 794 ±7.94 , 7 94 (±7.94) semelhantes 8078 80 78 80.7 ± ( 3.00 300 00 6880 68 68.8 ±3.62. 362 ±3.62 62 (±3.62) estudados Z3 011 11 0.1 002 ±0.02 02 (±0.024 2 ±5.19 519 19 (±5.19 3410 10 34.1 79 ±7.9 9 (±7.94 807 8 80. 3.0 30 688 6 68. 36 ±3.6 (±3.62 01 0. ±0.0 (±0.02 ±5.1 51 (±5.1 341 34. ±7. (±7.9 3. ±3. (±3.6 ±0. (±0.0 ±5. (±5. ±7 (±7. ±3 (±3. ±0 (±0. ±5 (±5 (±7 (±3 (±0
Abstract The objective of this work was to evaluate the mechanical performance of Z350 resin composite modified with Bombyx mori cocoons silk nanoparticles for dental applications. Four experimental groups were analyzed G0% = Filtek Z350 resin composite (control); G1% = Filtek Z350 with 1% of silk nanoparticles; G3% = Filtek Z350 with 3% of silk nanoparticles; G5% = Filtek Z350 with 5% of silk nanoparticles. It was employed scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction, 3-point flexural strength test, Knoop hardness test, and surface roughness. From 3-point flexural strength tests the control group presented the best results G0% = 113.33 MPa (±23.73). The higher flexural modulus was shown by groups G3% = 29.150 GPa (±5.191) and G5% = 34.101 GPa (±7.940), which are statistically similar. The Knoop microhardness test has shown statistical difference only among the G3% group between the top 80.78 (± 3.00) and bottom 68.80 (±3.62) and no difference between the groups. The roughness test presented no statistical difference between the groups. The incorporation of silk nanoparticles reduced the flexural strength of Z350 resin composite. The surface roughness and microhardness tests showed no changes in any of the groups studied. Z Z35 applications G0 G (control) G1 1 G3 3 G5 5 microscopy Xray X ray spectroscopy diffraction 3point point 11333 113 33 113.3 ±23.73. 2373 ±23.73 . 23 73 (±23.73) 29150 29 150 29.15 ±5.191 5191 191 (±5.191 34101 34 101 34.10 ±7.940, 7940 ±7.940 , 7 940 (±7.940) similar 8078 80 78 80.7 ± ( 3.00 300 00 6880 68 68.8 ±3.62 362 62 (±3.62 studied Z3 (control 1133 11 113. 237 ±23.7 2 (±23.73 2915 15 29.1 ±5.19 519 19 (±5.19 3410 10 34.1 794 ±7.94 94 (±7.940 807 8 80. 3.0 30 0 688 6 68. ±3.6 36 (±3.6 ±23. (±23.7 291 29. ±5.1 51 (±5.1 341 34. 79 ±7.9 9 (±7.94 3. ±3. (±3. ±23 (±23. ±5. (±5. ±7. (±7.9 ±3 (±3 ±2 (±23 ±5 (±5 ±7 (±7. (±2 (±7
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