ABSTRACT Planting is considered one of the most essential steps in coffee growing. Lack of uniformity in planting may compromise future operations. Therefore, verifying planting operations quality is fundamental to optimizing production processes and reducing costs. This study aimed to investigate planting techniques through Statistical Process Control (SPC) and aerial images. Carried out in two areas, managed manually and semi-mechanized in the Bom Jardim Farm (MG - Brazil). Data were collected through Remotely Piloted Aircraft (RPA). Quality control charts and density maps were used to identify variations in distribution and spacing between plants and planting rows. It was found that the planting carried out manually was 4.7% wider than projected due to spacing reduction from 0.5 m to 0.48 m. The semi-mechanized system displayed a deficit of 7% compared to the projected planting system, using 0.55 m between plants. The density map showed the most significant planting alignment variations. Despite displaying lower results than the manual system, the semi-mechanized system improvements are valid for their minimal average variations. Thus, correcting points found outside the limits can increase the efficiency of semi-mechanized planting. growing Therefore costs SPC (SPC images areas semimechanized semi mechanized MG Brazil. Brazil . Brazil) RPA. RPA (RPA) rows 47 4 7 4.7 05 0 5 0. 048 48 0.4 055 55 Thus (RPA 4. 04

We report a facile hydrothermal method for the synthesis of niobium pentoxide (Nb2O5) under two different temperatures, 120 °C (Nb2O5-120) and 150 °C (Nb2O5-150). The obtained materials were characterized by structural, optical and morphological techniques. Also, the photocatalytic properties of the Nb2O5 samples were evaluated in two reactions under ultraviolet (UVC) irradiation: degradation of methylene blue (MB) and indigo carmine (IC) dyes; and esterification of free fatty acids (FFA) present in waste cooking oil (WCO). The Nb2O5 was formed at different temperatures of synthesis, and the increase in temperature did not cause significant changes in the structural and optical characteristics, but resulted in an increased surface area of the synthesized materials. Both synthesized materials showed excellent efficiency for dye photodegradation. The sample Nb2O5-150 presented the best performance for the MB photodegradation, with almost 85% of the removal efficiency. In this case, the adsorption of MB molecules on the surface of the material was high due to the favorable electrostatic interaction and also because of its high surface area. For the IC photodegradation, the adsorption was insignificant, and both samples presented approximately 100% of the removal efficiency. These materials were also promising for the reduction of free fat acids in waste oil by photoesterification. NbO Nb O (Nb2O5 12 C Nb2O5120 (Nb2O5-120 15 Nb2O5150. Nb2O5150 . (Nb2O5-150) techniques Also Nb2O UVC (UVC irradiation (MB (IC dyes FFA (FFA WCO. WCO (WCO) characteristics photodegradation Nb2O5-15 85 case insignificant 100 photoesterification (Nb2O 1 Nb2O512 (Nb2O5-12 Nb2O515 (Nb2O5-150 (WCO Nb2O5-1 8 10 Nb2O51 (Nb2O5-1 (Nb2O5-15 Nb2O5- (Nb2O5-

The study of adsorption kinetics has been gaining ground, due to the fact that adsorption is an operation used in several areas, which drives the development of software for calculating kinetic parameters. In this context, the work aims to develop and validate a free software, with an intuitive interface and easy operation, for processing adsorption kinetic analysis data. The Adsorption Kinetics Calculation (AKC) software was developed in Java language, using Apache Netbeans IDE (integrated development environment) and has three kinetic equations implemented in a non-linear way: pseudo-first order, pseudo-second order and intraparticle diffusion implemented and also generates the parameters statistical coefficient of determination (R2) and ARE (average relative error). The software was successful in programming the algorithms, because the parameter values (Qe and C) were similar to the experimental values and the error values (R2 and ARE) were within those predicted by the literature. The software has the ability to plot the results and all results showed reliability in the data generated, and it can be concluded that it is validated and ready to be made available for users to use in their research. ground areas context AKC (AKC language integrated environment nonlinear non linear way pseudofirst pseudo first pseudosecond second R2 R average error. . error) algorithms Qe C (R literature generated research

RESUMO: Echinacea angustifolia é uma planta perene que vem sendo utilizada para tratar diversas enfermidades de origem microbiana. Neste estudo foram avaliadas propriedades antivirais, in vitro, de um extrato etanólico de E. angustifolia frente ao alphaherpesvírus bovino 1 (BoHV-1). BoHV-1 causa enfermidades que afetam principalmente o trato respiratório e genital de bovinos, e que resultam em grandes perdas econômicas. Quando células foram tratadas com o extrato de E. angustifolia em concentração não citotóxica em diferentes tempos (3, 6, ou 24h) antes da inoculação do BoHV-1, não foi possível detectar o vírus por até 72 horas após, enquanto que nas células não tratadas o vírus alcançou o título de 105.5TCID50/25µl (média). A incubação do extrato com BoHV-1 24 horas antes da inoculação celular não resultou em inativação da infectividade viral. Células infectadas com 103 TCID50 de BoHV-1 não tratadas com E. angustifolia apresentaram em média 45,8% de viabilidade após 48 horas da infecção, enquanto que 91,1% permaneceram viáveis quando tratadas após 6 horas ou 84,1% após 24 horas da infecção, demonstrando uma significativa redução no desenvolvimento de efeito citopático. Além disso, E. angustifolia reduziu significativamente a expressão relativa de mRNA das citocinas antivirais IFNα e IFNβ nas células tratadas, sugerindo que a atividade antiviral não ocorre devido a imunomodulação. E. angustifolia reduziu significativamente a expressão relativa de mRNA das citocinas antivirais IFNα e IFNβ nas células tratadas, indicando que a atividade antiviral não ocorre devido a imunomodulação. Os dados obtidos indicam que o extrato etanólico da E. angustifolia pode interferir com a adsorção, penetração e/ou o egresso viral das células infectadas. Tomados em conjunto, os dados apresentados enfatizam uma promissora atividade antiviral da E. angustifolia contra o BoHV-1. RESUMO microbiana vitro E BoHV1. BoHV1 BoHV . (BoHV-1) BoHV- bovinos econômicas 3, 3 (3 24h h BoHV1, 1, 7 1055TCID5025µl TCIDµl 105 5TCID50 25µl TCID µl média. (média) 2 10 TCID5 458 45 8 45,8 4 infecção 911 91 91,1 841 84 84,1 citopático disso imunomodulação adsorção eou conjunto 1. (BoHV-1 ( 5TCID5 (média 45, 9 91, 84, (BoHV- 5TCID (BoHV

ABSTRACT: Echinacea angustifolia is a perennial plant that has been traditionally used to treat various microbial diseases. This study evaluated the in vitro antiviral properties of an ethanolic extract of E. angustifolia against bovine alphaherpesvirus 1 (BoHV-1). BoHV-1 infection is associated with respiratory, reproductive and neurological disease in cattle, resulting in major economic losses. When cells were treated with E. angustifolia extract at a non-cytotoxic concentration at different times (3, 6 or 24 hours) before BoHV-1 inoculation, no viral detection was possible after 72h, while in untreated cells the virus reached a titer of 105.5TCID50 /25µl (median). Incubating the extract with BoHV-1 24 hours before cell inoculation did not result in loss of viral infectivity. Cells infected with 103 TCID50 of BoHV-1 and not treated with E. angustifolia showed an average of 45.8% viability after 48 hours of infection, while 91.1% remained viable when treated 6 hours after or 84.1% 24 hours after infection, demonstrating a significant reduction in the cytopathic effect. In addition, E. angustifolia significantly reduced the relative mRNA expression of the antiviral cytokines IFNα and IFNβ in the treated cells, suggesting that the antiviral activity is not due to immunomodulation. The obtained data indicated that the ethanolic extract of E. angustifolia may directly interfere with virus attachment, entry, and/or egress from infected cells. Taken together, the presented data emphasized the promising antiviral activity of E. angustifolia against BoHV-1. ABSTRACT diseases E BoHV1. BoHV1 BoHV . (BoHV-1) BoHV- respiratory cattle losses noncytotoxic non cytotoxic 3, 3 (3 2 72h h 1055TCID50 TCID 105 5TCID50 105.5TCID5 25µl µl median. median (median) infectivity 10 TCID5 458 45 8 45.8 4 911 91 91.1 841 84 84.1 effect addition immunomodulation attachment entry andor together 1. (BoHV-1 ( 1055TCID5 5TCID5 105.5TCID (median 45. 9 91. 84. (BoHV- 1055TCID 5TCID (BoHV

RESUMO: O estudo das relações genotípicas entre índices de tolerância à seca e caracteres agronômicos de interesse no melhoramento de trigo é útil para traçar estratégias de seleção. Objetivou-se com este trabalho investigar as relações de causa e efeito entre características agronômicas e índices de tolerância à seca via análise de correlações canônicas. Dois ensaios (controle e estresse) foram conduzidos no inverno de 2020 em Viçosa, MG, Brasil. Foram avaliados os caracteres (dias para o espigamento, altura da planta, massa e número de grãos por espiga, massa de cem grãos e rendimento de grãos). Os dados de produtividade dos ensaios de controle e estresse foram utilizados para construir cinco índices de tolerância à seca. Os dados foram submetidos à análise de modelos mistos para estimação dos parâmetros genéticos e predição dos valores genotípicos (REML/BLUP), em seguida, os valores genotípicos foram utilizados para calcular os coeficientes de correlação entre os caracteres. Dois grupos de caracteres foram estabelecidos para o estudo das correlações canônicas, sendo o primeiro grupo constituído pelas variáveis agronômicas e o segundo pelos índices de tolerância à seca. Houve efeito significativo de genótipo para todas as características avaliadas. Os pares canônicos foram significativos, o que indicou a existência de dependência entre os grupos. O caráter dias para o espigamento pode ser utilizado na seleção indireta de genótipos de trigo para tolerância à seca. RESUMO Objetivouse Objetivou se canônicas 202 Viçosa MG Brasil planta espiga grãos. . grãos) REML/BLUP, REMLBLUP REML/BLUP , REML BLUP (REML/BLUP) seguida avaliadas significativos 20 (REML/BLUP 2

ABSTRACT: The study of genotypic relationships between drought tolerance indices and agronomic traits of interest in wheat breeding is useful for designing selection strategies. The objective of this research was to investigate the cause-and-effect relationships between agronomic traits and drought tolerance indices through the analysis of canonical correlations. Two trials (control and stress) were conducted in winter 2020 in Viçosa, MG, Brazil. The traits evaluated were: (days for heading, plant height, mass and number of grains per spike, mass of one hundred grains, and grain yield). Grain yield data from the control and stress conditions were used to construct five drought tolerance indices. The data were subjected to mixed model analysis for estimation of genetic parameters and prediction of genotypic values (REML/BLUP), and then the genotypic values were used to calculate the correlation coefficients between the traits. Two groups of traits were established for the study of canonical correlations, the first group consisting of agronomic traits and the second by drought tolerance indices. There was a significant genotype effect for all evaluated traits. The canonical pairs were significant, which indicated the existence of dependence between the groups. Days to heading trait can be used in the indirect selection of wheat genotypes for drought tolerance. ABSTRACT strategies causeandeffect cause correlations 202 Viçosa MG Brazil days height spike yield. . yield) REML/BLUP, REMLBLUP REML/BLUP , REML BLUP (REML/BLUP) 20 (REML/BLUP 2

RESUMO: O estudo foi realizado em um ovino, fêmea, de três anos de idade, da raça santa inês, procedente de uma propriedade localizada do município de Santo Antônio de Tauá, oeste do Pará. O animal acometido tinha histórico de exoftalmia no olho esquerdo, secreção nasal e dificuldade respiratória há mais de três meses. Ao exame físico o animal apresentava baixo escore corporal, apatia, assimetria facial unilateral, moderada exoftalmia unilateral esquerda, dispneia mista e exsudação nasal serossanguinolenta profusa unilateral. À necropsia, foi observada grande massa nasal, predominantemente branco-amarelada com áreas vermelho enegrecidas, de superfície irregular, finamente granular, úmida e friável. A massa invadia desde a junção mucocutânea do nariz esquerdo até as coanas, se infiltrava pelos seios nasais frontais, placa cribiforme e alcançava as meninges e a porção frontal do cérebro. À microscopia da superfície do epitélio nasal notou-se severa destruição dos cornetos e dos epitélios, evidenciada por extensas áreas de necrose com muitos debris celulares, ulceração e infecção bacteriana secundária. No sistema nervoso central (SNC) havia meningite piogranulomatosa com acentuada congestão de vasos, focos de necrose e inflamação granulomatosa. O diagnóstico de rinite granulomatosa de origem micótica associada ao fungo Conidiobolus lamprauges foi baseado nos achados da imuno-histoquímica. RESUMO ovino fêmea idade inês Tauá Pará meses corporal apatia esquerda necropsia brancoamarelada branco amarelada enegrecidas irregular granular friável coanas frontais cérebro notouse notou epitélios celulares secundária SNC (SNC vasos imunohistoquímica. imunohistoquímica imuno histoquímica. histoquímica imuno-histoquímica

ABSTRACT: The study was conducted on a 3-year-old female Santa Inês sheep from a property located in the municipality of Santo Antônio de Tauá, west of Pará. The affected animal had a history of exophthalmos in the left eye, nasal discharge, and breathing difficulty for more than three months. On physical examination, the animal had a low body score, apathy, unilateral facial asymmetry, moderate unilateral left exophthalmos, mixed dyspnea and unilateral profuse serosanguinous nasal discharge. At necropsy, a large nasal mass was observed, predominantly yellowish-white with blackish-red areas, with an irregular, finely granular, moist, and friable surface. The mass invaded from the mucocutaneous junction of the left nostril to the choanae, infiltrated the frontal sinuses, the cribiform plate, and reached the meninges and the frontal portion of the brain. Microscopy of the surface of the nasal epithelium showed severe destruction of the turbinates and epithelia, evidenced by extensive areas of necrosis with a large amount of cellular debris, ulceration, and secondary bacterial infection. In the central nervous system there was pyogranulomatous meningitis with marked vessel congestion, as well as foci of necrosis and granulomatous inflammation. Immunohistochemistry showed intense staining of numerous intralesional hyphae for antibodies against Conidiobolus lamprauges. The diagnosis of granulomatous rhinitis of mycotic origin associated with the Conidiobolus lamprauges was based on epidemiological, clinical-pathological, and immunohistochemical data. ABSTRACT 3yearold yearold 3 year old Tauá Pará eye discharge months examination score apathy asymmetry necropsy observed yellowishwhite yellowish white blackishred blackish red irregular granular moist choanae sinuses plate brain epithelia debris ulceration infection congestion inflammation epidemiological clinicalpathological, clinicalpathological clinical pathological, pathological clinical-pathological data

RESUMO: Uma das causas de perda de produtividade em lavouras de cana está associada à espécie Diatraea saccharalis, também conhecida por broca da cana. Portanto, este estudo avaliou a viabilidade do uso de sensores hiperespectrais para obter a resposta espectral foliar da cana-de-açúcar em diferentes períodos de infestações, tanto a nível foliar quanto dossel, a fim de diagnosticar antecipadamente os danos da Diatraea saccharalis. O estudo contou com três variedades de cana-de-açúcar: CTC9003BT, CTC4 e RB966928. Em metade das parcelas foi utilizado o inseticida Altacor® para o controle de pragas. As coletas de dados ocorreram nas fases: brotação, perfilhamento, crescimento de colmos e início da maturação. Para avaliar os efeitos da broca na cana foi coletado os dados referentes ao conteúdo relativo de água (CRA), assinatura espectral foliar em laboratório e dossel, índices de vegetação (NDVI e MCARI), produtividade, pureza e ATR (Açúcar Total Recuperável). O maior CRA encontrado foi para a CTC9003BT (60,15%) sem inseticida e 59,0% com inseticida. As faixas espectrais do visível (400-680 nm) e infravermelho próximo (750-1300 nm) identificaram variações espectrais nas plantas com e sem broca. O percentual de broca apresentou correlações altas e negativas entre a produtividade, NDVI e ATR, com coeficientes de -0,68, -0,76 e -0,76, respectivamente. Os índices NDVI e MCARI foram eficazes na detecção de plantas sob estresse, contudo, sua variação é influenciada por múltiplos fatores, sendo difícil associá-los a um único problema (broca). RESUMO saccharalis Portanto canadeaçúcar açúcar infestações dossel CTCBT CTC BT RB966928 RB Altacor pragas fases brotação perfilhamento maturação CRA, , (CRA) MCARI, MCARI) Açúcar Recuperável. Recuperável . Recuperável) 60,15% 6015 60 15 (60,15% 590 59 0 59,0 400680 400 680 (400-68 nm 7501300 750 1300 (750-130 0,68, 068 68 -0,68 0,76 076 76 -0,7 0,76, respectivamente estresse contudo fatores associálos associá los (broca) RB96692 (CRA 60,15 601 6 1 (60,15 5 59, 40068 40 (400-6 750130 75 130 (750-13 0,68 06 -0,6 0,7 07 7 -0, (broca RB9669 60,1 (60,1 4006 4 (400- 75013 13 (750-1 0,6 0, -0 RB966 60, (60, (400 7501 (750- - RB96 (60 (40 (750 RB9 (6 (4 (75 ( (7

ABSTRACT: One of the causes of productivity loss in sugarcane cultivation has been associated with the species Diatraea saccharalis, also known as the sugarcane borer. Therefore, this study evaluated the feasibility of using hyperspectral sensors to obtain the leaf spectral response of sugarcane in different periods of infestation at leaf and canopy levels to diagnose D. saccharalis damage in advance. The study included three varieties of sugarcane: CTC9003BT, CTC4, and RB966928. The insecticide Altacor® was used to control pestsin half of the plots. Data collection occurred at the following stages: sprouting, tillering, stalke longation, and early maturation. Data regarding relative water content (RWC), leaf spectral signature in the laboratory and canopy, vegetation indices (NDVI and MCARI), productivity, purity, and total recoverable sugar (TRS) were collected to evaluate the borer effects on the sugarcane crop. The highest RWC was observed for CTC9003BT (60.15%) without insecticide and 59.0% with insecticide. The visible (400-680 nm) and near-infrared (750-1300 nm) spectral bands identified spectral variations in plants with and without sugarcane borer. The percentage of sugarcane borer showed high and negative correlations between productivity, NDVI, and TRS, with coefficients of -0.68, -0.76, and -0.76, respectively. The NDVI and MCARI indices effectively detect plants under stress, but their variation is influenced by multiple factors, making it difficult to associate them with a single problem (sugarcane borer). ABSTRACT Therefore D advance CTCBT CTC BT CTC4 RB966928 RB Altacor plots stages sprouting tillering longation maturation RWC, , (RWC) MCARI, MCARI) purity TRS (TRS crop 60.15% 6015 60 15 (60.15% 590 59 0 59.0 400680 400 680 (400-68 nm nearinfrared near infrared 7501300 750 1300 (750-130 0.68, 068 68 -0.68 0.76, 076 76 -0.76 respectively stress factors . borer) RB96692 (RWC 60.15 601 6 1 (60.15 5 59. 40068 40 (400-6 750130 75 130 (750-13 0.68 06 -0.6 0.76 07 7 -0.7 RB9669 60.1 (60.1 4006 4 (400- 75013 13 (750-1 0.6 -0. 0.7 RB966 60. (60. (400 7501 (750- 0. -0 RB96 (60 (40 (750 - RB9 (6 (4 (75 ( (7

ABSTRACT There is great interest in varieties with greater competitive ability against weeds. This can be facilitated by path analysis, which involves the statistical evaluation and interpretation of the relationship between yield and its components. In this analysis, the occurrence of multicollinearity results in inconsistent estimates of the coefficients, and overestimates of the direct effects of the explanatory variables on the response variable. The aim of this study was to identify the characteristics with the greatest direct effect on pod yield and green and dry bean yields in traditional cowpea varieties, evaluated in competition with weeds in two experiments. In addition, the presence of multicollinearity was investigated in the analyses. In Experiment-1, twelve varieties with the highest bean yields in a preliminary evaluation were assessed in a randomized block design with five replications. In Experiment-2, six varieties, selected in the preliminary evaluation, were assessed using two methods of weed management: three of the most productive and three of the least productive. Randomized blocks and split plots were used, with five replications. Multicollinearity, indicated by the number of conditions and the variance inflation values, was greater in Experiment-2. In the six cases under study (three yields x two experiments), the number of pods per plant had the greatest direct effect on yield. analysis components coefficients variable experiments addition analyses Experiment1, Experiment1 Experiment 1, 1 Experiment-1 replications Experiment2, Experiment2 2, 2 Experiment-2 management used Multicollinearity values Experiment2. 2. experiments, , experiments) Experiment-

RESUMO: O lúpulo (Humulus lupulus L.) possui grande importância econômica no planalto serrano do estado de Santa Catarina, uma vez que existem inúmeras cervejarias nesta região do Brasil. Como as cultivares disponíveis no país carecem de bons atributos qualitativos e apresentam baixa produtividade de cones, existe grande demanda por genótipos melhorados. Os resultados de experimentos de cruzamento dialélico aumentam a compreensão dos processos de herança e dos mecanismos de controle associados à transferência de alelos com ação aditiva ou não aditiva, permitindo assim que os geneticistas explorem os benefícios da heterose. Os objetivos deste estudo foram avaliar as capacidades de combinação geral e específica (CGC e CEC, respectivamente) de quatro genótipos de lúpulo e obter híbridos F1 com características agronômicas superiores às dos genitores e habilidade para se adaptar às condições ambientais do planalto catarinense. Os cruzamentos dialélicos parciais foram realizados em delineamento de blocos casualizados envolvendo 14 tratamentos, i.e. dois genitores masculinos (Cascade e Hallertauer), quatro genitores femininos (Columbus, Chinook, Cascade e Hallertauer) e oito combinações híbridas, com três repetições cada. Os resultados mostraram que a CEC dos genitores foi o mecanismo de controle predominante para a manifestação nos híbridos das características comprimento do ramo lateral, altura de inserção do primeiro cone, massa verde da planta e produtividade de cones. Algumas combinações entre genitores também manifestaram CGC elevada, indicando a presença de alelos favoráveis com ação aditiva. A melhor combinação foi Hallertauer × Cascade e essa descoberta demonstra a importância da escolha de genitores originários de diferentes grupos genéticos (Americano × Europeu) para obter híbridos geneticamente melhorados. RESUMO Humulus L. L Catarina Brasil cones melhorados heterose respectivamente F catarinense 1 tratamentos ie i i.e Hallertauer, , Columbus, Columbus (Columbus Chinook híbridas cada lateral cone elevada Americano Europeu

ABSTRACT: Hops (Humulus lupulus L.) are of particular economic importance in the highlands of the state of Santa Catarina, Brazil, by virtue of the number of breweries in the region. However, since the cultivars currently available in the country present poor qualitative attributes and low cone productivity, there is considerable demand for improved genotypes. The results of diallel crossing experiments help to increase our understanding of inheritance processes and the mechanisms controlling the transfer of alleles with additive or non-additive action, thereby allowing breeders to explore the benefits of heterosis. The present study evaluated the general and specific combining abilities (GCA and SCA, respectively) of four hop genotypes and to obtain F1 hybrids with agronomic traits superior to those of the parents and the ability to adapt to the environmental conditions in the Santa Catarina highlands. Partial diallel crosses were performed using a randomized complete block design involving 14 treatments, namely two male parents (Cascade and Hallertauer), four female parents (Columbus, Chinook, Cascade and Hallertauer) and eight hybrid combinations, with three repetitions each. The results showed that SCA was the predominant controlling mechanism for the manifestation in hybrids of the traits length of the lateral branch, height of insertion of the first cone, plant green mass and cone productivity. Some parental combinations also exhibited high GCA, indicating the presence of favorable alleles with additive action. The best combination was Hallertauer × Cascade, a finding that highlights the importance of choosing parents from different gene pools (American × European) to obtain genetically enhanced hybrids. ABSTRACT Humulus L. L Brazil region However productivity nonadditive non action heterosis GCA respectively F 1 treatments Hallertauer, , Columbus, Columbus (Columbus Chinook each branch American European

RESUMO: As neoplasias neuroepiteliais presentes no sistema ventricular originam-se das células que revestem o plexo coroide e podem ser benignas ou malignas, como é o caso do carcinoma de plexo coroide. Um equino, de quatro anos de idade, apresentando quadro neurológico com síndrome encefálica de quinze dias de evolução, foi encaminhado para atendimento veterinário. Ao exame apresentava apatia, ataxia severa, desvio lateral de cabeça, andar em círculos, pressão da cabeça contra obstáculos, diminuição do tônus da cauda, anosmia, ausência da resposta de ameaça visual, ausência de sensibilidade na face e hipotonia de língua. Líquido cefalorraquidiano apresentava pleocitose mista, aumento de proteína e diminuição de glicose. Após o óbito o animal foi diagnosticado com carcinoma de plexo coroide em terceiro ventrículo após exame histopatológico e imunohistoquímico. Conclui-se que equinos podem apresentar tumores em SNC, como o carcinoma de plexo coroide, com sintomatologia clínica inespecífica, tratamento clínico inefetivo e diagnóstico conclusivo realizado no exame post mortem. RESUMO originamse originam se malignas equino idade evolução veterinário apatia severa círculos obstáculos cauda anosmia visual língua mista glicose imunohistoquímico Concluise Conclui SNC inespecífica mortem

ABSTRACT: Neuroepithelial neoplasms present in the ventricular system originate from the cells lining the choroid plexus and can be benign or malignant, such as choroid plexus carcinoma. A four-year-old equine presenting with a fifteen-day history of neurological symptoms was sent for veterinary evaluation. Upon examination, the horse exhibited apathy, severe ataxia, head tilt, circling behavior, head pressing, decreased tail tone, anosmia, absence of menace response, lack of facial sensitivity, and lingual hypotonia. Cerebrospinal fluid analysis revealed mixed pleocytosis, increased protein, and decreased glucose. Following the animal’s death, histopathological and immunohistochemical examinations confirmed the diagnosis of choroid plexus carcinoma in the third ventricle. It is concluded that horses may develop central nervous system tumors, such as choroid plexus carcinoma, with nonspecific clinical symptoms, ineffective clinical treatment, and a conclusive diagnosis established postmortem. ABSTRACT malignant fouryearold four year old fifteenday fifteen day evaluation examination apathy ataxia tilt behavior pressing tone anosmia response sensitivity hypotonia pleocytosis protein glucose animals animal s death ventricle tumors treatment postmortem

ABSTRACT BACKGROUND: Studies have shown an association between the clinical severity of coronavirus disease (COVID-19) and sociodemographic and clinical variables in older adults. However, few studies have described the explanatory factors of the relationship between these variables and the clinical severity of COVID-19 using structural equation modeling. OBJECTIVE: To analyze the factors directly and indirectly associated with the clinical severity of coronavirus disease (COVID-19) among older adults in Minas Gerais, Brazil. DESIGN AND SETTING: Retrospective epidemiological study. METHODS: This study included 51,141 elderly adults with COVID-19 living in Minas Gerais, Brazil. Data were collected through the Individual Registration Form – Hospitalized Cases of Severe Acute Respiratory Syndrome from January 28, 2020, to January 27, 2022. RESULTS: Older age (P < 0.001), male sex (P < 0.001), dyspnea (P < 0.001), change in chest X-ray examination findings (P < 0.001), greater number of risk factors/comorbidities (P < 0.001), and longer hospitalization time (P < 0.001) were directly associated with the clinical severity of COVID-19. Female sex, mediated by the greater number of risk/comorbidity factors (β = -0.02, P < 0.001), and younger age, mediated by longer hospitalization time (β = -0.01; P < 0.001), were indirectly associated with the clinical severity of COVID-19. CONCLUSION: Demographic and clinical variables were directly associated with increased disease severity. In addition to the direct effect, a greater number of risk/comorbidity factors and longer hospitalization time mediated the association between demographic variables and outcomes. BACKGROUND COVID19 COVID 19 (COVID-19 However COVID-1 modeling OBJECTIVE Gerais Brazil SETTING METHODS 51141 51 141 51,14 28 2020 27 2022 RESULTS 0.001, 0001 0.001 , 0 001 Xray X ray factorscomorbidities comorbidities COVID19. 19. riskcomorbidity comorbidity β 0.02, 002 02 -0.02 0.01 01 -0.01 CONCLUSION effect outcomes COVID1 1 (COVID-1 COVID- 5114 5 14 51,1 2 202 000 0.00 00 0.02 -0.0 0.0 (COVID- 511 51, 20 -0. 0. (COVID -0 -

ABSTRACT BACKGROUND: The Kerlan-Jobe Orthopedic Clinic (KJOC) Shoulder and Elbow Score is commonly used to assess the functional status of athletes with conditions affecting the shoulder and elbow. However, a Brazilian Portuguese version of the KJOC questionnaire is currently unavailable. OBJECTIVES: This study aimed to develop a Brazilian Portuguese version of the KJOC questionnaire. DESIGN AND SETTING: This translation and cultural adaptation study was conducted at the Federal University of Paraíba, Brazil. METHODS: The procedures adopted in this study followed guidelines recommending translation by two independent translators, synthesis of the translations, back-translation performed by two native English-speaking translators, analysis by an expert committee, and pre-testing. The Portuguese version was tested with 32 athletes to assess their understanding of the assessment tool. Items were deemed adequate if they were understood by at least 90% of the athletes. RESULTS: The terms and expressions of some original items were modified to achieve better comprehensibility in the Brazilian context. No further modifications were necessary after the pre-test; all terms were comprehensible to over 90% of athletes. CONCLUSION: The translation and cultural adaptation of the KJOC questionnaire into Portuguese were completed, resulting in a Brazilian version of the scale. Further studies are needed to evaluate the reliability and validity of this scale. BACKGROUND KerlanJobe Kerlan Jobe (KJOC elbow However unavailable OBJECTIVES SETTING Paraíba Brazil METHODS translators translations backtranslation back Englishspeaking English speaking committee pretesting. pretesting pre testing. testing pre-testing 3 tool 90 RESULTS context pretest test pre-test CONCLUSION completed scale 9

ABSTRACT BACKGROUND: Prenatal depression threatens maternal and child well-being and interferes with issues prioritized by the 2030 agenda for the Sustainable Development Goals. OBJECTIVES: This study aimed to estimate the prevalence of depressive disorders during pregnancy using the Patient Health Questionnaire-9 (PHQ-9). DESIGN AND SETTING: A cross-sectional study using a sample of pregnant Brazilian women, representative of Brazil as a whole. METHODS: Data were obtained from the National Health Survey 2019 (PNS-2019), as coordinated by the Instituto Brasileiro de Geografia e Estatística (IBGE). Women aged 18-49 years who were pregnant during PNS-2019 data collection were included. The prevalence of depressive disorders and 95% confidence intervals (95%CI) were calculated. RESULTS: The prevalence of depression before the current pregnancy was 6.03% (95%CI: 3.80%; 8.25%). Using the PHQ-9, the prevalence of Major Depressive Disorder (MDD) in the current pregnancy was estimated to be 17.39% (95%CI: 12.70%–22.06%) among pregnant women who were targeted by the PNS-2019. Moreover, MDD was 15.26% (95%CI: 10.54%; 19.97%) among those who were free from depression history and in half of the pregnant woman population with depression history. Suicidal ideation has been reported in almost 23% of pregnant women with a history of depression. The two items from Patient Health Questionnaire-2 (PHQ-2) (anhedonia and depressed mood) with a cutoff of ≥ 3 presented similar results. CONCLUSIONS: Depression during pregnancy affects a non-negligible proportion of pregnant women, thus constituting an important public health problem. Therefore, it is crucial to discuss the implementation of regular screening for depression during prenatal care programs in Brazil. BACKGROUND wellbeing well being 203 Goals OBJECTIVES Questionnaire9 Questionnaire 9 Questionnaire- PHQ9. PHQ9 PHQ . (PHQ-9) SETTING crosssectional cross sectional whole METHODS 201 PNS2019, PNS2019 PNS , (PNS-2019) IBGE. IBGE (IBGE) 1849 18 49 18-4 PNS-201 included 95 95%CI 95CI CI (95%CI calculated RESULTS 603 6 03 6.03 3.80% 380 80 8.25%. 825 8.25% 8 25 8.25%) PHQ9, 9, PHQ-9 (MDD 1739 17 39 17.39 12.70%–22.06% 12702206 12 70 22 06 PNS2019. 2019. Moreover 1526 15 26 15.26 10.54% 1054 10 54 19.97% 1997 19 97 23 Questionnaire2 2 PHQ2 (PHQ-2 anhedonia mood results CONCLUSIONS nonnegligible non negligible problem Therefore 20 (PHQ-9 PNS201 (PNS-2019 (IBGE 184 1 4 18- PNS-20 60 0 6.0 3.80 38 82 8.25 PHQ- 173 17.3 12.70%–22.06 1270220 7 152 15.2 10.54 105 5 19.97 199 (PHQ- PNS20 (PNS-201 PNS-2 6. 3.8 8.2 17. 12.70%–22.0 127022 15. 10.5 19.9 (PHQ PNS2 (PNS-20 PNS- 3. 8. 12.70%–22. 12702 10. 19. (PNS-2 12.70%–22 1270 (PNS- 12.70%–2 127 (PNS 12.70%– 12.70% 12.70 12.7 12.