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Resumo O estudo analisou a distribuição espacial e as desigualdades sociais na cobertura vacinal para COVID-19 entre crianças de 5 a 11 anos no Brasil. As coberturas vacinais foram calculadas para os municípios brasileiros e analisadas por região geográfica e decis com base no Índice de Desenvolvimento Humano (IDH-M) e expectativa de escolaridade aos 18 anos. Modelos multiníveis foram usados para determinar o coeficiente de partição da variância, e a estatística local bivariada de Moran I foi usada para avaliar a associação espacial. Os resultados mostraram diferenças significativas nas taxas de cobertura vacinal entre os municípios, com menor cobertura nas regiões Norte e Centro-Oeste. Municípios com menor IDH e anos de escolaridade esperados apresentaram menores taxas de cobertura vacinal. A análise de agrupamento bivariado identificou extensas concentrações de municípios nas regiões Norte e Nordeste com baixa cobertura vacinal e baixo desenvolvimento humano, enquanto alguns aglomerados de municípios nas regiões Sudeste e Sul com baixa cobertura localizavam-se em áreas com alto IDH-M. Essas descobertas destacam as desigualdades persistentes em nível municipal na cobertura vacinal entre crianças e a necessidade de intervenções para melhorar o acesso e a cobertura vacinal em áreas mais vulneráveis. COVID19 COVID 19 COVID-1 1 Brasil IDHM M (IDH-M variância CentroOeste. CentroOeste Centro Oeste. Oeste Centro-Oeste humano localizavamse localizavam se IDHM. M. IDH-M vulneráveis COVID1 COVID-

Abstract This study examined the spatial distribution and social inequalities in COVID-19 vaccine coverage among children aged 5-11 in Brazil. First and second dose vaccine coverage was calculated for all Brazilian municipalities and analyzed by geographic region and deciles based on human development index (HDI-M) and expected years of schooling at 18 years of age. Multilevel models were used to determine the variance partition coefficient, and bivariate local Moran’s I statistic was used to assess spatial association. Results showed significant differences in vaccine coverage rates among Brazilian municipalities, with lower coverage in the North and Midwest regions. Municipalities with lower HDI and expected years of schooling had consistently lower vaccine coverage rates. Bivariate clustering analysis identified extensive concentrations of municipalities in the Northern and Northeastern regions with low vaccine coverage and low human development, while some clusters of municipalities in the Southeast and South regions with low coverage were located in areas with high HDI-M. These findings highlight the persistent municipal-level inequalities in vaccine coverage among children in Brazil and the need for targeted interventions to improve vaccine access and coverage in underserved areas. COVID19 COVID 19 COVID-1 511 5 11 5-1 HDIM M (HDI-M 1 age coefficient Morans Moran s association HDIM. M. HDI-M municipallevel municipal level COVID1 COVID- 51 5-

https://doi.org/10.1590/1413-81232024298.03952023

Progression of valve heart disease in a cohort of patients undergoing renal replacement therapy
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Tompson, Maria Eduarda Cavalcanti

; Pimentel, José Arthur Viana de Oliveira

; Silva, Manuella de Amorim

; Santos-Veloso, Marcelo Antônio Oliveira

; Lordsleem, Andrea Bezerra de Melo da Silveira

; Lima, Sandro Gonçalves de

Brazilian Journal of Nephrology

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jun 2024, Volume 46 N. 2 elocation e20230036

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: Doenças cardiovasculares são uma causa significativa de morte em pacientes com Doença Renal Crônica (DRC). A calcificação valvar é preditor de mortalidade cardiovascular e doença arterial coronariana. Objetivo: Avaliar a frequência, fatores associados e progressão de valvopatias em pacientes com DRC. Métodos: Coorte retrospectiva com 291 pacientes ambulatoriais no Hospital das Clínicas de Pernambuco. Inclusão: ≥18 anos com DRC e valvopatia; exclusão: tratamento conservador ou dados incompletos. Variáveis clínicas e laboratoriais foram comparadas e categorizadas por tempo de terapia dialítica (TTD): <5 anos, 5–10 anos, >10 anos. Foram aplicados os testes Qui-quadrado, exato de Fisher, ANOVA, Kruskal-Wallis. Associação entre valvopatia e TTD foi avaliada por regressão binária. Significância foi definida como p < 0,05. Resultados: A valvopatia mitral foi encontrada em 82,5% (240) dos casos, seguida da aórtica (65,6%; 86). Houve progressão da doença valvar em 106 (36,4%) pacientes. Não houve associação entre valvopatias aórtica, pulmonar, mitral ou tricúspide e TTD. Hiperparatireoidismo secundário foi a única variável explicativa significativa na regressão para valvopatia mitral (OR 2,59 [IC95%: 1,09–6,18]; p = 0,031). Conclusão: Encontramos alta frequência de valvopatias, especialmente mitral e aórtica, aem pacientes com DRC. Não houve associação entre TTD e valvopatia. Introdução . (DRC) coronariana Objetivo Métodos 29 Pernambuco Inclusão 18 ≥1 exclusão incompletos (TTD) 5 510 10 5–1 >1 Quiquadrado, Quiquadrado Qui quadrado, quadrado Qui-quadrado Fisher ANOVA KruskalWallis. KruskalWallis Kruskal Wallis. Wallis Kruskal-Wallis binária 005 0 05 0,05 Resultados 825 82 82,5 240 (240 casos 65,6% 656 65 6 (65,6% 86. 86 86) 36,4% 364 36 4 (36,4% pulmonar OR 259 2 59 2,5 IC95% IC95 IC [IC95% 1,09–6,18 109618 1 09 1,09–6,18] 0,031. 0031 0,031 031 0,031) Conclusão (DRC ≥ (TTD 51 5– > 00 0,0 8 82, 24 (24 65,6 (65,6 36,4 3 (36,4 25 2, IC9 [IC95 1,09–6,1 10961 003 0,03 03 0, (2 65, (65, 36, (36, [IC9 1,09–6, 1096 ( (65 (36 [IC 1,09–6 109 (6 (3 1,09– 1,09 1,0 1,

Abstract Introduction: Cardiovascular disease is an important cause of death among patients with chronic kidney disease (CKD). Valve calcification is a predictor of cardiovascular mortality and coronary artery disease. Objective: To assess heart valve disease frequency, associated factors, and progression in CKD patients. Methods: We conducted a retrospective study on 291 CKD patients at Hospital das Clínicas de Pernambuco. Inclusion criteria were age ≥ 18 with CKD and valve disease, while those on conservative management or with missing data were excluded. Clinical and laboratory variables were compared, and patients were categorized by dialysis duration (<5 years; 5–10 years; >10 years). Statistical tests, including chi-square, Fisher’s exact, ANOVA, and Kruskal-Wallis, were employed as needed. Simple and multivariate binary regression models were used to analyze valve disease associations with dialysis duration. Significance was defined as p < 0.05. Results: Mitral valve disease was present in 82.5% (240) of patients, followed by aortic valve disease (65.6%; 86). Over time, 106 (36.4%) patients developed valve disease. No significant association was found between aortic, pulmonary, mitral, or tricuspid valve disease and dialysis duration. Secondary hyperparathyroidism was the sole statistically significant factor for mitral valve disease in the regression model (OR 2.59 [95% CI: 1.09–6.18]; p = 0.031). Conclusion: CKD patients on renal replacement therapy exhibit a high frequency of valve disease, particularly mitral and aortic valve disease. However, no link was established between dialysis duration and valve disease occurrence or progression. Introduction CKD. . (CKD) Objective factors Methods 29 Pernambuco 1 excluded compared <5 5 (< years 510 10 5–1 >1 years. years) tests chisquare, chisquare chi square, square chi-square Fishers Fisher s exact ANOVA KruskalWallis, KruskalWallis Kruskal Wallis, Wallis Kruskal-Wallis needed 005 0 05 0.05 Results 825 82 82.5 240 (240 65.6% 656 65 6 (65.6% 86. 86 86) time 36.4% 364 36 4 (36.4% pulmonary OR 259 2 59 2.5 95% 95 [95 CI 1.09–6.18 109618 09 1.09–6.18] 0.031. 0031 0.031 031 0.031) Conclusion However (CKD ( 51 5– > 00 0.0 8 82. 24 (24 65.6 (65.6 36.4 3 (36.4 25 2. 9 [9 1.09–6.1 10961 003 0.03 03 0. (2 65. (65. 36. (36. [ 1.09–6. 1096 (65 (36 1.09–6 109 (6 (3 1.09– 1.09 1.0 1.

https://doi.org/10.1590/2175-8239-jbn-2023-0036en

Spatial clusters and social inequities in COVID-19 vaccine coverage among children in Brazil
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Boing, Alexandra Crispim

; Boing, Antonio Fernando

; Borges, Marcelo Eduardo

; Rodrigues, Denis de Oliveira

; Barberia, Lorena

; Subramanian, SV

Ciência & Saúde Coletiva

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2024, Volume 29 N. 8 elocation e03952023

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232024298.03952023

Semisynthesis and Cytotoxic Activities of Novel Oxime Ester Derivatives of the Diterpene Stemodin
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Oliveira, José Augusto C. de

; Alves Filho, Carlos José

; Lima, Antônio Marcelo A.

; Pessoa, Cláudia do Ó

; Oliveira, Fátima de Cássia E. de

; Miranda, Fátima N.

; Mattos, Marcos Carlos de

; Oliveira, Maria Conceição F.

; Mafezoli, Jair

; Barbosa, Francisco Geraldo

Journal of the Brazilian Chemical Society

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2024, Volume 35 N. 6 elocation e-20230193

Abstract: En | Text: En | PDF: En

Stemodin (1) is a diterpene produced by Stemodia maritima L. (Scrophulariaceae) and shows antiviral and tumor cell proliferation inhibitory activities. Chemical modifications of 1 were performed to produce the known stemodinone (2), two new stemodinone oximes, Z (3) and E (4), and seven new oxime esters derivatives (5, 6, 7, 8, 9, 10, and 11). All derivatives were evaluated for their cytotoxic activity in HL60 (promyelocytic leukemia), SNB-19 (astrocytoma), HCT-116 (colon carcinoma), and PC3 (prostate) human cancer cell lines, and L929 (healthy murine cells). Oximes 3 and 4 showed lower cytotoxic values than 1 against all cancer cell lines tested. However, esters 9 and 10 exhibited cell growth inhibition percentages higher than 1 against PC3, SNB-19, and HCT-116 cancer cell lines, ranging from 62.96 to 94.27%. Many of these values exceed that presented by doxorubicin (66.05-86.87%). All compounds showed no cytotoxic effect on healthy cells at the tested concentration of 25 µg mL-1. (1 L Scrophulariaceae (Scrophulariaceae activities 2, 2 , (2) oximes (3 4, (4) 5, 5 (5 6 7 8 11. 11 . 11) HL HL6 promyelocytic leukemia, leukemia leukemia) SNB19 SNB 19 SNB-1 astrocytoma, astrocytoma (astrocytoma) HCT116 HCT 116 HCT-11 colon carcinoma, carcinoma carcinoma) PC prostate (prostate L92 cells. cells) However SNB19, 19, 6296 62 96 62.9 9427 94 27 94.27% 66.0586.87%. 66058687 66.05 86.87% 66 05 86 87 (66.05-86.87%) mL1. mL1 mL 1. mL-1 ( (2 (4 SNB1 SNB- (astrocytoma HCT11 HCT-1 L9 629 62. 942 94.27 0586 66.0586.87% 6605868 6605 66.0 8687 86.87 0 (66.05-86.87% mL- HCT1 HCT- 94.2 058 66.0586.87 660586 660 66. 868 86.8 (66.05-86.87 94. 66.0586.8 66058 86. (66.05-86.8 66.0586. (66.05-86. 66.0586 (66.05-86 66.058 (66.05-8 (66.05- (66.05 (66.0 (66. (66 (6

https://doi.org/10.21577/0103-5053.20230193

Democracia, amizade, serenidade: Aristóteles entre Vaz, Weil e Bobbio Democracia amizade serenidade Vaz
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Perine, Marcelo

; Andrade, Paulo Raphael Oliveira

Revista de Filosofia Aurora

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2024, Volume 36 elocation e202430082

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O artigo propõe uma interlocução de três pensadores contemporâneos do campo da filosofia política sobre o conceito de democracia, Lima Vaz (1921-2002), Eric Weil (1904-1977) e Norberto Bobbio (1909-2004), confrontado com a concepção aristotélica da amizade política sustentada pela benevolência (eúnoia) e pela concórdia (homónoia) entre todos os cidadãos. A reflexão final sobre a serenidade, definida por Bobbio como a “mais impolítica das virtudes”, inscreve o presente artigo nas homenagens a Antonio José Romera Valverde pela sua longa e fecunda carreira acadêmica. democracia 19212002, 19212002 1921 2002 , (1921-2002) 19041977 1904 1977 (1904-1977 19092004, 19092004 1909 2004 (1909-2004) eúnoia (eúnoia homónoia (homónoia cidadãos serenidade mais virtudes, virtudes virtudes” acadêmica 1921200 192 200 (1921-2002 1904197 190 197 (1904-197 1909200 (1909-2004 192120 19 20 (1921-200 190419 (1904-19 190920 (1909-200 19212 1 2 (1921-20 19041 (1904-1 19092 (1909-20 (1921-2 (1904- (1909-2 (1921- (1904 (1909- (1921 (190 (1909 (192 (19 (1 (

Abstract The article proposes a dialogue between three contemporary thinkers in the field of political philosophy on the concept of democracy, Lima Vaz (1921-2002), Eric Weil (1904-1977) and Norberto Bobbio (1909-2004), confronted with the Aristotelian conception of political friendship sustained by benevolence (eúnoia) and concord (homónoia) among all citizens. The final reflection on serenity, defined by Bobbio as the “most impolite of virtues”, inscribes this article as a tribute to Antonio José Romera Valverde for his long and fruitful academic career. democracy 19212002, 19212002 1921 2002 , (1921-2002) 19041977 1904 1977 (1904-1977 19092004, 19092004 1909 2004 (1909-2004) eúnoia (eúnoia homónoia (homónoia citizens serenity most virtues, virtues virtues” career 1921200 192 200 (1921-2002 1904197 190 197 (1904-197 1909200 (1909-2004 192120 19 20 (1921-200 190419 (1904-19 190920 (1909-200 19212 1 2 (1921-20 19041 (1904-1 19092 (1909-20 (1921-2 (1904- (1909-2 (1921- (1904 (1909- (1921 (190 (1909 (192 (19 (1 (

https://doi.org/10.1590/2965-1557.036.e202430082

Production of Chives Using Organic Fertilizers before Planting and in Top Dressing
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Oliveira, Marcelo Munhoz Venâncio de

; Alves, Thatiane Nepomuceno

; Cardoso, Antonio Ismael Inácio

; Luís, Débora Cristina Mastroleo

; Carvalho, Joseantonio Ribeiro de

Brazilian Archives of Biology and Technology

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2024, Volume 67 elocation e24230542

Abstract: En | Text: En | PDF: En

Abstract Chives are one of the most popular spice plants in world cuisine. It is usually produced by small producers, often in an organic farming system. However, research with chives in this production system is lacking. The purpose of this study was to evaluate the production of chives with the use of organic fertilizers before planting and in top dressing. Seven treatments were evaluated, resulting from the factorial 2x3+1, with two organic fertilizers (castor bean cake and hoof and horn powder) x 3 application modes (100% before planting; 100% in top dressing; 50% before planting and 50% in top dressing) + 1 control (without these organic fertilizers). The experimental design was in randomized blocks, with five replications and plots of 1 m2. The relative index of chlorophyll (“Spad” index), height, number of leaves, fresh and dry weight of the plants were evaluated. All treatments of the factorial were better than the control, showing that these organic fertilizers improve production in chives. It is recommended to use the hoof and horn powder in installments (50% before planting and 50% in top dressing) or 100% in top dressing, the latter option being more interesting for reducing the need for labor, with just one application moment. cuisine producers However lacking dressing evaluated 2x31 2x3 2x3+1 castor 100 (100 50 without fertilizers. . fertilizers) blocks m2 m Spad (“Spad index, , index) height leaves (50 labor moment 2x 2x3+ 10 (10 5 (5 (1 (

https://doi.org/10.1590/1678-4324-2024230542

Development and performance of graphene oxide reinforced LDPE nanocomposite polymers for 3D printing D
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Silva, Bryan M. M.

; Tegon, Caroline C.

; Soares, Marcelo M.

; Gonçalves, Rodolfo Luiz Prazeres

; Oliveira, Andressa A.

; Couto, Antonio Augusto

; Massi, Marcos

REM - International Engineering Journal

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2024, Volume 77 N. 2 elocation e230059

Abstract: En | Text: En | PDF: En

Abstract This study evaluated the mechanical properties and the chemical and thermal characteristics of low-density polyethylene (LDPE) nanocomposites reinforced with graphene oxide for manufacturing via 3D printing. LDPE nanocomposites with different graphene oxide (GO) loadings (0.5% and 1.5%) were processed by a single-screw extruder. To characterize the pre-injected material, Fourier transform infrared spectroscopy (FTIR) and thermal characterization with thermogravimetry (TGA) were used. The injected material was also characterized with mechanical impact and traction tests. The results showed that incorporating GO into the polymeric matrix added hydroxyl groups to the matrix structure, with a 39.13% increase in Young's modulus for LDPE-1.5%wtGO samples. Mechanical tests of 3D printed samples showed that, with an increase in the amount of GO in the polymer matrix, the composite loses ductility, enabling its use in 3D printing technologies and thus encouraging new studies on printed materials for various applications. lowdensity low density (LDPE D (GO 0.5% 05 0 5 (0.5 1.5% 15 1 singlescrew single screw extruder preinjected pre FTIR (FTIR TGA (TGA used structure 3913 39 13 39.13 Youngs Young s LDPE1.5%wtGO LDPE15wtGO LDPEwtGO 1.5%wtGO wtGO ductility applications 0.5 (0. 1.5 391 3 39.1 LDPE1 15wtGO 0. (0 1. 39. (

https://doi.org/10.1590/0370-44672023770059

Diretriz de Avaliação Cardiovascular Perioperatória da Sociedade Brasileira de Cardiologia – 2024 202 20 2
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Gualandro, Danielle Menosi

; Fornari, Luciana Savoy

; Caramelli, Bruno

; Abizaid, Alexandre Antonio Cunha

; Gomes, Brenno Rizerio

; Tavares, Caio de Assis Moura

; Fernandes, Caio Julio Cesar dos Santos

; Polanczyk, Carisi Anne

; Jardim, Carlos

; Vieira, Carolina Leticia Zilli

; Pinho, Claudio

; Calderaro, Daniela

; Schreen, Dirk

; Marcondes-Braga, Fabiana Goulart

; Souza, Fábio de

; Cardozo, Francisco Akira Malta

; Tarasoutchi, Flavio

; Carmo, Gabriel Assis Lopes

; Kanhouche, Gabriel

; Lima, José Jayme Galvão de

; Bichuette, Luciana Dornfeld

; Sacilotto, Luciana

; Drager, Luciano Ferreira

; Vacanti, Luciano Janussi

; Gowdak, Luis Henrique Wolff

; Vieira, Marcelo Luiz Campos

; Martins, Marcelo Luiz Floriano Melo

; Lima, Márcio Silva Miguel

; Lottenberg, Marcos Pita

; Aliberti, Márlon Juliano Romero

; Marchi, Mauricio Felippi de Sá

; Paixão, Milena Ribeiro

; Oliveira Junior, Mucio Tavares de

; Yu, Pai Ching

; Cury, Patricia Ramos

; Farsky, Pedro Silvio

; Pessoa, Ranna Santos

; Siciliano, Rinaldo Focaccia

; Accorsi, Tarso Augusto Duenhas

; Correia, Vinícius Machado

; Mathias Junior, Wilson

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 9 elocation e20240590

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.36660/abc.20240590

Impact of milk fat source and level on the productive performance of suckling goat kids
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Oliveira Neto, Antônio Paulo de

; Rodrigues, Marcelo Teixeira

; Oliveira, Tadeu Silva

Pesquisa Agropecuária Brasileira

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2024, Volume 59 elocation e03585

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste trabalho foi avaliar o consumo, a digestibilidade dos nutrientes e o ganho de peso de cabritas lactentes alimentadas com leite de cabra e de vaca com diferentes níveis de gordura. Trinta e duas cabras mestiças lactentes foram distribuídas em arranjo fatorial 2×2, em delineamento inteiramente casualizado. Foram avaliadas duas fontes de gordura (leite de cabra e vaca) e dois níveis de adição de gordura no leite (3,5 e 7,0%) durante 97 dias, em oito repetições. O consumo de matéria seca foi influenciado pela fonte e pelo teor de gordura do leite. A maior ingestão de nutrientes foi observada com leite de cabra com 7,0% de gordura. O consumo de proteína bruta foi afetado apenas pela fonte de gordura devido à maior presença de proteína no leite de cabra, enquanto o consumo de gordura bruta foi afetado apenas pelos níveis de gordura. O ganho de peso médio diário foi maior para as cabritas que ingeriram leite com 7,0% de gordura. A fonte de gordura não afetou a digestibilidade dos nutrientes, mas os níveis de gordura influenciaram a digestibilidade da matéria seca. A inclusão do nível de 7,0% de gordura no leite aumenta o ganho de peso das cabritas sem afetar a digestibilidade da gordura. A gordura de leite de cabra aumenta o peso ao desmame possivelmente devido à maior ingestão de calorias. 22 2 2×2 casualizado 3,5 35 3 5 (3, 70 7 0 9 dias repetições 7,0 calorias 2× 3, (3 7, (

Abstract The objective of this work was to evaluate the food intake, nutrient digestibility, and weight gain of female suckling goat kids fed with goat and cow milk with different levels of fat. Thirty-two crossbred goats in the suckling phase were distributed in a 2×2 factorial arrangement, in a completely randomized design. Two sources of fat (goat and cow milk) and two levels of fat addition to milk (3.5 and 7.0%) were evaluated for 97 days in eight replicates. Dry matter intake was affected by milk source and fat levels. The highest nutrient intake was observed with goat milk with 7.0% fat. Crude protein intake was affected only by fat source due to the greater presence of protein in goat milk, whereas crude fat intake was affected only by fat levels. The average daily gain was higher for goat kids that ingested milk with 7.0% fat. The source of fat did not affect nutrient digestibility, but the levels of fat influenced dry matter digestibility. The inclusion of 7.0% fat in milk increases the weight gain of suckling goat kids without affecting fat digestibility. Fat from goat milk increases weight at weaning possibly due to a higher energy intake. digestibility Thirtytwo Thirty 22 2 2× arrangement design 3.5 35 3 5 (3. 70 7 0 9 replicates 7.0 3. (3 7. (

https://doi.org/10.1590/s1678-3921.pab2024.v59.03585

10.

Diretriz sobre Diagnóstico e Tratamento da Cardiomiopatia Hipertrófica – 2024 202 20 2
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Fernandes, Fabio

; Simões, Marcus V.

; Correia, Edileide de Barros

; Marcondes-Braga, Fabiana Goulart

; Coelho-Filho, Otavio Rizzi

; Mesquita, Cláudio Tinoco

; Mathias Junior, Wilson

; Antunes, Murillo de Oliveira

; Arteaga-Fernández, Edmundo

; Rochitte, Carlos Eduardo

; Ramires, Felix José Alvarez

; Alves, Silvia Marinho Martins

; Montera, Marcelo Westerlund

; Lopes, Renato Delascio

; Oliveira Junior, Mucio Tavares de

; Scolari, Fernando Luis

; Avila, Walkiria Samuel

; Canesin, Manoel Fernandes

; Bocchi, Edimar Alcides

; Bacal, Fernando

; Moura, Lidia Zytynski

; Saad, Eduardo Benchimol

; Scanavacca, Mauricio Ibrahim

; Valdigem, Bruno Pereira

; Cano, Manuel Nicolas

; Abizaid, Alexandre Antonio Cunha

; Ribeiro, Henrique Barbosa

; Lemos Neto, Pedro Alves

; Ribeiro, Gustavo Calado de Aguiar

; Jatene, Fabio Biscegli

; Dias, Ricardo Ribeiro

; Beck-da-Silva, Luis

; Rohde, Luis Eduardo Paim

; Bittencourt, Marcelo Imbroinise

; Pereira, Alexandre da Costa

; Krieger, José Eduardo

; Villacorta Junior, Humberto

; Martins, Wolney de Andrade

; Figueiredo Neto, José Albuquerque de

; Cardoso, Juliano Novaes

; Pastore, Carlos Alberto

; Jatene, Ieda Biscegli

; Tanaka, Ana Cristina Sayuri

; Hotta, Viviane Tiemi

; Romano, Minna Moreira Dias

; Albuquerque, Denilson Campos de

; Mourilhe-Rocha, Ricardo

; Hajjar, Ludhmila Abrahão

; Brito Junior, Fabio Sandoli de

; Caramelli, Bruno

; Calderaro, Daniela

; Farsky, Pedro Silvio

; Colafranceschi, Alexandre Siciliano

; Pinto, Ibraim Masciarelli Francisco

; Vieira, Marcelo Luiz Campos

; Danzmann, Luiz Claudio

; Barberato, Silvio Henrique

; Mady, Charles

; Martinelli Filho, Martino

; Torbey, Ana Flavia Malheiros

; Schwartzmann, Pedro Vellosa

; Macedo, Ariane Vieira Scarlatelli

; Ferreira, Silvia Moreira Ayub

; Schmidt, Andre

; Melo, Marcelo Dantas Tavares de

; Lima Filho, Moysés Oliveira

; Sposito, Andrei C.

; Brito, Flávio de Souza

; Biolo, Andreia

; Madrini Junior, Vagner

; Rizk, Stephanie Itala

; Mesquita, Evandro Tinoco

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 7 elocation e202400415

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.36660/abc.20240415

11.

Physical traits of eggs from free-range domestic hens of the Sura variety in Northeast Brazil freerange free range
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Machado, Leandra Polliny M.

; Cavalcante, Diego Helcias

; Costa, Márcio da Silva

; Oliveira, Marcelo Richelly A.

; Sousa Junior, Antônio

; Almeida, Marcos Jacob de Oliveira

; Araujo, Adriana Mello de

Revista Brasileira de Saúde e Produção Animal

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2024, Volume 25 elocation e20230040

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Este estudo teve como objetivo analisar as características físicas dos ovos de galinhas caipiras var. Suras. Foram analisados um total de 100 ovos, onde diversos parâmetros físicos, tais como pesagem do ovo inteiro, medição do diâmetro equatorial e altura do ovo, classificação da cor da casca, miragem para verificação da presença de fendas na casca, determinação da altura da câmara de ar, classificação da cor da gema, verificação da presença de manchas de carne e manchas de sangue, medição da largura e comprimento do albúmen, medição do diâmetro da gema, pesagem da gema, e pesagem da casca. Foram posteriormente determinados o peso do albúmen por diferença entre o peso do ovo e pesos da casca e gema, determinação percentual dos diferentes constituintes do ovo, shape index (índice de forma) e shell index (índice de casca). A análise estatística foi realizada pelo GLM programa SAS (SAS Institute). O resultado comparando as médias de cada parâmetro estudado demonstrou que os ovos da variedade Sura em ambas as classes comerciais (Grande e Pequenos), possuem formato mais arredondado, com casca marrom clara e gema mais alaranjada. Portanto, os parâmetros avaliados confirmam que os ovos provenientes de galinhas var. Suras possuem características que podem favorecer nichos de mercado e assim incentivar a produção destas aves, mantendo a biodiversidade e contrariando a extinção das mesmas. var 10 físicos inteiro ar sangue índice forma . casca) Institute. Institute Institute) Grande Pequenos, Pequenos , Pequenos) arredondado alaranjada Portanto aves mesmas 1

ABSTRACT This study aimed to analyze the physical characteristics of eggs from free-range hens of the Sura variety. One hundred eggs underwent assessment of various physical parameters, namely, whole egg weight, equatorial diameter, egg height, shell color, presence of cracks via candling, air chamber height, yolk color, presence of flesh and blood spots, albumen width and length, yolk diameter, yolk weight, and shell weight. Additional analyses included determining the albumen weight (calculated by subtracting the weights of the shell and yolk from the total egg weight), percentages of egg components, shape index, and shell index. Statistical analyses were conducted using GLM SAS software (SAS Institute). The results revealed distinct physical traits; eggs from the Sura variety, regardless of size class (large or small), typically have a more rounded shape, light brown shells, and more orange yolks. These findings confirm that Sura variety eggs possess unique characteristics that could appeal to specific market niches, potentially promoting the production of these birds, supporting biodiversity, and aiding in the prevention of their extinction. freerange free range parameters namely diameter height color candling spots length calculated , weight) components index Institute. Institute . Institute) traits large small, small small) shells yolks niches birds biodiversity extinction

https://doi.org/10.1590/s1519-994020230040

12.

Histological study of adventitious rooting in Acacia mearnsii and Ilex paraguariensis mini-cuttings: insights into the so-called anatomical barrier minicuttings mini cuttings mini-cuttings socalled so called
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Oliveira, João Marcelo Santos de

; Bisognin, Dilson Antônio

; Muniz, Marlove Fátima Brião

; Gazzana, Denise

; Santos, Marjana Machado dos

Rodriguésia

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2024, Volume 75 elocation e01402023

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Acacia mearnsii e Ilex paraguariensis são espécies arbóreas de grande importância social e econômica no Brasil, que demandam cultivares clonais. Seus brotos possuem estoque de células totipotentes com potencial adequado para enraizamento adventício, essencial para a produção em massa de mudas de alta qualidade. Este estudo teve como objetivo obter novas perspectivas sobre como as barreiras anatômicas, ou seja, tecidos esclerificados na região cortical, podem afetar o enraizamento adventício de miniestacas dessas espécies por meio de estudos histológicos. Para ambas as espécies, a análise histológica revelou características diagnósticas significativas. O apodrecimento de tecidos parece ser equivalente a uma barreira anatômica em A. mearnsii. A abundância de amido foi notável em clones com maior competência de enraizamento de I. paraguariensis, porém não foram observados grãos de amido nos tecidos fundamentais de A. mearnsii, independentemente da competência de enraizamento do clone. As principais diferenças ao enraizamento adventício estavam associadas à velocidade de resposta, que se inicia a partir de meristemoides corticais, seguida pela diferenciação do tecido condutor a partir de um tecido neoformado com estrutura parenquimática, que conecta a periferia com o tecido vascular secundário. Portanto, esse tecido neoformado promove a base estrutural necessária para conexões vasculares radiais. Para ambas as espécies estudadas, a rizogênese apresenta barreiras distintas ao enraizamento, contudo estas não são necessariamente de natureza anatômica. Brasil clonais qualidade anatômicas seja cortical histológicos significativas I clone resposta corticais parenquimática secundário Portanto radiais estudadas

Abstract Acacia mearnsii and Ilex paraguariensis are tree species of great social and economic importance in Brazil, demanding clonal cultivars. Their shoots possess a reservoir of totipotent cells with suitable potential for adventitious rooting, essential for mass production of high-quality seedlings. This study aimed to gain new insights into how anatomical barriers, i.e. sclerified tissues in the cortical region, may affect the adventitious rooting of cuttings from these species through histological examinations. For both species, histological analysis revealed significant diagnostic features. Tissue decay appears to be equivalent to an anatomical barrier in A. mearnsii. Starch abundance was notable in clones with higher rooting competence of I. paraguariensis, but they were not observed in the fundamental tissues of A. mearnsii, regardless of the rooting competence of the clone. The main differences in adventitious rooting were associated with the speed of response, initiated from cortical meristems, followed by differentiation of conductive tissue from newly formed tissue, connecting the periphery with the secondary vascular tissue. Thus, this newly formed tissue with parenchymatic structure provides the necessary structural basis for radial vascular connections. For both studied species, rhizogenesis presents distinct barriers to rooting, nevertheless these are not necessarily of anatomical nature. Brazil cultivars highquality high quality seedlings ie i e i.e region examinations features A I clone response meristems Thus connections nature

https://doi.org/10.1590/2175-7860202475034

13.

Evaluation of the Main Variables that Influence the Sediment Connectivity Based on Applied Models
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Oliveira, Warlen Librelon de

; Nero, Marcelo Antonio

; Macedo, Diego Rodrigues

GEOUSP

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2024, Volume 28 N. 1 elocation e-196088

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo O índice de conectividade hidrossedimentológica determina o grau de possibilidade que os sedimentos de uma determinada área chegue a um ponto de controle. Compreender a dinâmica que ocorre com os sedimentos requer o uso de variáveis que representam a morfologia e as condições ambientais envolvidas no espaço e no tempo. Esta pesquisa propõe a análise de modelos, identificando as principais variáveis que explicam a conectividade de sedimentos e observando as influências e frequências de uso delas. Com base em 35 artigos específicos que trataram de modelos de conectividade de sedimentos, foi constatada uma representatividade importante do uso de modelos digitais de elevação em 85% dos trabalhos, com destaque para variáveis de declividade, área de drenagem, além do uso da terra. A rugosidade, apesar de extrema importância, foi usada apenas com dados tabelados, podendo assim ser um elemento a ser detalhado em novos modelos. controle tempo delas 3 85 trabalhos declividade drenagem terra rugosidade importância tabelados 8

Abstract The hydro-sedimentological connectivity index determines the degree of possibility that sediments from a given area reach a control point. To understand the dynamics that occur with sediments, the use of variables that represent the morphology and environmental conditions involved in space and time is necessary. This research proposed the analysis of models, identifying the main variables that explain the connectivity of sediments and observing their influences and frequency of use. Based on 35 specific articles that addressed sediment connectivity models, an important representativeness of the use of digital elevation models was found in 85% of the studies, emphasizing slope variables, drainage area, and land use and cover. Roughness was used only with tabulated data, despite being extremely important, thus being able to be an element to be detailed in new models. hydrosedimentological hydro sedimentological point necessary 3 85 studies cover data 8

Resumen El índice de conectividad hidrosedimentológica determina el grado de posibilidad de que los sedimentos de una zona determinada lleguen a un punto de control. Comprender la dinámica que ocurre con los sedimentos requiere el uso de variables que representen la morfología y las condiciones ambientales involucradas en el espacio y el tiempo. Esta investigación propuso el análisis de modelos, identificando las principales variables que explican la conectividad de los sedimentos y observando sus influencias y frecuencia de uso. A partir de 35 artículos específicos que abordaron modelos de conectividad de sedimentos, se encontró una representatividad importante del uso de modelos digitales de elevación en el 85% de los trabajos, con énfasis en variables de pendiente, área de drenaje, además del uso del suelo. La rugosidad, a pesar de ser sumamente importante, se utilizó únicamente con datos tabulados, pudiendo así ser un elemento a detallar en nuevos modelos. control tiempo 3 85 trabajos pendiente drenaje suelo rugosidad tabulados 8

https://doi.org/10.11606/issn.2179-0892.geousp.2024.196088.en

14.

To be or not to B27 positive: implications for the phenotypes of axial spondyloarthritis outcomes. Data from a large multiracial cohort from the Brazilian Registry of Spondyloarthritis B B2 positive outcomes
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Resende, Gustavo Gomes

; Saad, Carla Goncalves Schahin

; Marques, Claudia Diniz Lopes

; Ribeiro, Sandra Lúcia Euzébio

; Gavi, Maria Bernadete Renoldi de Oliveira

; Yazbek, Michel Alexandre

; Marinho, Adriana de Oliveira

; Menin, Rita de Cássia

; Ochtrop, Manuella Lima Gomes

; Soares, Andressa Miozzo

; Cavalcanti, Nara Gualberto

; Carneiro, Jamille Nascimento

; Werner de Castro, Glaucio Ricardo

; Fernandes, José Mauro Carneiro

; Souza, Elziane da Cruz Ribeiro E

; Alvarenga, Corina Quental de Menezes

; Vieira, Rejane Maria Rodrigues de Abreu

; Machado, Natalia Pereira

; Ximenes, Antônio Carlos

; Gazzeta, Morgana Ohira

; Albuquerque, Cleandro Pires de

; Skare, Thelma Larocca

; Keiserman, Mauro Waldemar

; Kohem, Charles Lubianca

; Benacon, Gabriel Sarkis

; Rocha, Vítor Florêncio Santos

; Lage, Ricardo da Cruz

; Malheiro, Olivio Brito

; Golebiovski, Rywka Tenenbaum Medeiros

; Oliveira, Thauana Luiza

; Duque, Ruben Horst

; Londe, Ana Carolina

; Pinheiro, Marcelo de Medeiros

; Sampaio-Barros, Percival Degrava

Advances in Rheumatology

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2024, Volume 64 elocation 33

Abstract: En | Text: En | PDF: En

Abstract Background There is a remarkable variability in the frequency of HLA-B27 positivity in patients with spondyloarthritis (SpA), which may be associated with different clinical presentations worldwide. However, there is a lack of data considering ethnicity and sex on the evaluation of the main clinical and prognostic outcomes in mixed-race populations. The aim of this study was to evaluate the frequency of HLA-B27 and its correlation with disease parameters in a large population of patients from the Brazilian Registry of Spondyloarthritis (RBE). Methods The RBE is a multicenter, observational, prospective cohort that enrolled patients with SpA from 46 centers representing all five geographic regions of Brazil. The inclusion criteria were as follow: (1) diagnosis of axSpA by an expert rheumatologist; (2) age ≥18 years; (3) classification according to ASAS axial. The following data were collected via a standardized protocol: demographic data, disease parameters and treatment historical. Results A total of 1096 patients were included, with 73.4% HLA-B27 positivity and a mean age of 44.4 (±13.2) years. Positive HLA-B27 was significantly associated with male sex, earlier age at disease onset and diagnosis, uveitis, and family history of SpA. Conversely, negative HLA-B27 was associated with psoriasis, higher peripheral involvement and disease activity, worse quality of life and mobility. Conclusions Our data showed that HLA-B27 positivity was associated with a classic axSpA pattern quite similar to that of Caucasian axSpA patients around the world. Furthermore, its absence was associated with peripheral manifestations and worse outcomes, suggesting a relevant phenotypic difference in a highly miscegenated population. HLAB27 HLAB HLA B27 B HLA-B2 SpA, , (SpA) worldwide However mixedrace mixed race populations RBE. . (RBE) multicenter observational 4 Brazil follow 1 (1 rheumatologist 2 (2 18 ≥1 years 3 (3 axial protocol historical 109 included 734 73 73.4 444 44 44. ±13.2 132 13 (±13.2 uveitis Conversely psoriasis activity mobility world Furthermore HLAB2 B2 HLA-B (SpA (RBE ( ≥ 10 7 73. ±13. (±13. ±13 (±13 ±1 (±1 ± (±

https://doi.org/10.1186/s42358-024-00372-0

15.

Análise das Notificações Recebidas pela Central de Transplantes do Estado de Roraima de 2017 a 2021 201 202 20 2
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Oliveira, Lidiane Cristina Santiago de

; Mendes, Larissa Lima Araújo

; Brum, Matheus Dantas

; Lima, Mykaelle Soares

; Lobo, Ana Carolina Ferrer

; França, Jéssica Anne Pereira Corrêa

; Santos Junior, Carlos Henrique dos

; Mota, Lueli Evelin Leite

; Maia Neto, Geraldo Pereira

; Araújo, José Egberg Santos de

; Rabelo, Matilde Nascimento

; Paz, Thaís Lorena Pereira da

; Lustosa, Victor Hugo Souza

; Santos, Bárbara Carvalho dos

; Linhares, Marcelo Moura

Brazilian Journal of Transplantation

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2024, Volume 27 elocation e1724

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivos: Analisar as notificações de morte encefálica (ME) recebidas pela Central de Transplantes (CET) do estado de Roraima (RR) de 2017 a 2021. Métodos: Trata-se de estudo transversal, quantitativo e observacional no qual foram analisadas todas as notificações recebidas pela CET no período de 2017 a 2021, resultando em 120 pacientes, dos seguintes centros de saúde: Hospital Geral de Roraima (HGR), Hospital Confederação Nacional das Cooperativas Médicas (UNIMED), Hospital da Criança Santo Antônio (HCSA), Hospital das Clínicas (HC) e Hospital Lotty Íris (HLI). Os dados foram coletados do sistema de gerenciamento de dados da central e repassados para a ficha de coleta desenvolvida pela pesquisadora. Resultados: Este estudo analisou 119 notificações após a exclusão de uma devido a dados conflitantes. Houve predominância do sexo masculino (58%), com trauma cranioencefálico sendo a causa mais frequente de ME. Ao todo, foram realizadas seis captações de órgãos, todas no HGR. Este estudo não encontrou associações significativas entre a captação de órgãos e sexo, idade, local de internação e ano. Conclusão: Há grandes desafios em relação à doação de órgãos em RR, com uma taxa de captação baixa ao longo de 5 anos. Apenas o HGR obteve sucesso em realizar captações de órgãos, diferentemente de outros hospitais notificadores. São necessárias melhorias, destacando a importância de se realizarem mais estudos para uma análise mais aprofundada dos dados. Objetivos ME (ME (CET RR (RR 201 2021 Métodos Tratase Trata transversal 12 pacientes saúde HGR, , (HGR) UNIMED, UNIMED (UNIMED) HCSA, HCSA (HCSA) HC (HC HLI. HLI . (HLI) pesquisadora Resultados 11 conflitantes 58%, 58 58% (58%) todo idade ano Conclusão anos notificadores melhorias 20 202 1 (HGR (UNIMED (HCSA (HLI (58% 2 (58 (5 (

ABSTRACT Objectives: To analyze brain death (BD) notifications received by Central de Transplantes (CET) in the state of Roraima (RR) from 2017 to 2021. Methods: This is a cross-sectional, quantitative, and observational study, where all notifications received by CET from 2017 to 2021 were analyzed, resulting in 120 patients from health the following centers: Hospital Geral de Roraima (HGR), Hospital Confederação Nacional das Cooperativas Médicas (UNIMED), Hospital da Criança Santo Antônio (HCSA), Hospital das Clínicas (HC), and Hospital Lotty Íris (HLI). The data were collected from the center’s data management system and passed on to the collection form developed by the researcher. Results: This study analyzed 119 notifications after excluding one due to conflicting data. There was a predominance of males (58%), with traumatic brain injury being the most frequent cause of BD. Six organ harvestings were carried out, all at the HGR. This study found no significant associations between organ procurement and sex, age, place of hospitalization, and year. Conclusion: There are considerable challenges concerning organ donation in RR, with a low uptake rate over five years. Only the HGR successfully carried out organ harvesting, while other reporting hospitals were unsuccessful. Improvements are needed, highlighting the importance of more studies for a more in-depth data analysis. Objectives BD (BD (CET RR (RR 201 Methods crosssectional, crosssectional cross sectional, sectional cross-sectional quantitative 202 12 centers HGR, , (HGR) UNIMED, UNIMED (UNIMED) HCSA, HCSA (HCSA) HC, HC (HC) HLI. HLI . (HLI) center s researcher Results 11 58%, 58 58% (58%) sex age hospitalization year Conclusion years harvesting unsuccessful needed indepth depth analysis 20 1 (HGR (UNIMED (HCSA (HC (HLI 5 (58% 2 (58 (5 (

https://doi.org/10.53855/bjt.v27i1.548_port

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