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1.
Spatiotemporal analysis of diarrhea-related hospitalizations of children in Brazil’s Midwest region from 2011 to 2020
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RESUMO Objetivo: Examinar a variabilidade espaçotemporal e identificar clusters de hospitalização por diarreia em crianças menores de cinco anos de idade de Mato Grosso, de 2011 a 2020. Métodos: Um estudo ecológico foi conduzido utilizando os registros de hospitalização por diarreia do Sistema de Informação Hospitalar/Sistema Único de Saúde. O risco relativo de hospitalização por diarreia em cada município foi calculado utilizando o software SaTScan, considerando-se o nível de significância estatística de 5% e 999 replicações de Monte Carlo. Resultados: O total de 13.315 hospitalizações por diarreia em crianças menores de cinco anos de idade foram registradas. As taxas anuais de hospitalização por diarreia reduziram de 8,50 para 3,45/1.000 nascidos vivos em crianças menores de um ano de idade e de 4,99 para 1,57 em crianças de 1–4 anos de idade, de 2011 a 2020. Clusters de municípios com alto risco relativo para hospitalização por diarreia, estatisticamente significantes, predominaram nas macrorregiões administrativas de saúde Norte, Nordeste e Sudoeste de Mato Grosso para crianças de ambos os grupos etários, até 2016. De 2016 a 2020, clusters de baixo risco relativo foram identificados nas macrorregiões administrativas de saúde Norte e Centro-Sul para crianças menores de cinco anos de idade. Conclusão: Os resultados mostraram redução das taxas de hospitalização por diarreia em crianças menores de cinco anos de idade, com a presença de clusters de baixo risco em Mato Grosso nos últimos anos estudados. Os monitoramentos de saúde pública devem incorporar análises espaciais na investigação da morbidade por diarreia.
ABSTRACT Objective: To examine spatiotemporal variability and identify clustering patterns of hospitalization rates for diarrhea in children younger than five years in Mato Grosso, Brazil, from 2011 to 2020. Methods: An ecological study was conducted using hospitalization records associated with diarrhea from the Brazilian Hospital Information System/Unified Health System. The relative risk of hospitalization for diarrhea in each municipality was calculated using SaTScan software considering a statistical significance level of 5% and 999 Monte Carlo replications. Results: A total of 13,315 diarrhea-associated hospitalizations for 5-year-old children were recorded. From 2011 to 2020, the annual rates for hospitalizations related to diarrhea decreased from 8.50 to 3.45/1,000 live births among children younger than one year and from 4.99 to 1.57 for children aged 1–4 years. Clusters of municipalities with high relative risk for hospitalizations due to diarrhea, statistically significant, predominated in the North, Northeast, and Southwest health administrative macro-regions of Mato Grosso for both age groups until 2016. From 2016 to 2020, clusters of the lowest relative risk were identified in the North and Center South health administrative macro-regions for children younger than five years. Conclusion: Results showed that hospitalization rates for diarrhea in children younger than five years reduced with the presence of low-risk clusters in Mato Grosso in the final years of the study. Public health surveillance should incorporate spatial analysis to investigate the diarrhea-related morbidity.
2.
Spatiotemporal analysis of diarrhea-related hospitalizations of children in Brazil’s Midwest region from 2011 to 2020 diarrhearelated diarrhea related Brazils Brazil s 201 202 20 2
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RESUMO Objetivo: Examinar a variabilidade espaçotemporal e identificar clusters de hospitalização por diarreia em crianças menores de cinco anos de idade de Mato Grosso, de 2011 a 2020. Métodos: Um estudo ecológico foi conduzido utilizando os registros de hospitalização por diarreia do Sistema de Informação Hospitalar/Sistema Único de Saúde. O risco relativo de hospitalização por diarreia em cada município foi calculado utilizando o software SaTScan, considerando-se o nível de significância estatística de 5% e 999 replicações de Monte Carlo. Resultados: O total de 13.315 hospitalizações por diarreia em crianças menores de cinco anos de idade foram registradas. As taxas anuais de hospitalização por diarreia reduziram de 8,50 para 3,45/1.000 nascidos vivos em crianças menores de um ano de idade e de 4,99 para 1,57 em crianças de 1–4 anos de idade, de 2011 a 2020. Clusters de municípios com alto risco relativo para hospitalização por diarreia, estatisticamente significantes, predominaram nas macrorregiões administrativas de saúde Norte, Nordeste e Sudoeste de Mato Grosso para crianças de ambos os grupos etários, até 2016. De 2016 a 2020, clusters de baixo risco relativo foram identificados nas macrorregiões administrativas de saúde Norte e Centro-Sul para crianças menores de cinco anos de idade. Conclusão: Os resultados mostraram redução das taxas de hospitalização por diarreia em crianças menores de cinco anos de idade, com a presença de clusters de baixo risco em Mato Grosso nos últimos anos estudados. Os monitoramentos de saúde pública devem incorporar análises espaciais na investigação da morbidade por diarreia. Objetivo 201 2020 Métodos HospitalarSistema Hospitalar Saúde SaTScan considerandose considerando se 5 99 Carlo Resultados 13315 13 315 13.31 registradas 850 8 50 8,5 3451000 3 45 1 000 3,45/1.00 499 4 4,9 157 57 1,5 14 1– significantes etários CentroSul Centro Sul Conclusão estudados 20 202 9 1331 31 13.3 85 8, 345100 00 3,45/1.0 49 4, 15 1, 2 133 13. 34510 0 3,45/1. 3451 3,45/1 345 3,45/ 34 3,45 3,4 3,
ABSTRACT Objective: To examine spatiotemporal variability and identify clustering patterns of hospitalization rates for diarrhea in children younger than five years in Mato Grosso, Brazil, from 2011 to 2020. Methods: An ecological study was conducted using hospitalization records associated with diarrhea from the Brazilian Hospital Information System/Unified Health System. The relative risk of hospitalization for diarrhea in each municipality was calculated using SaTScan software considering a statistical significance level of 5% and 999 Monte Carlo replications. Results: A total of 13,315 diarrhea-associated hospitalizations for 5-year-old children were recorded. From 2011 to 2020, the annual rates for hospitalizations related to diarrhea decreased from 8.50 to 3.45/1,000 live births among children younger than one year and from 4.99 to 1.57 for children aged 1–4 years. Clusters of municipalities with high relative risk for hospitalizations due to diarrhea, statistically significant, predominated in the North, Northeast, and Southwest health administrative macro-regions of Mato Grosso for both age groups until 2016. From 2016 to 2020, clusters of the lowest relative risk were identified in the North and Center South health administrative macro-regions for children younger than five years. Conclusion: Results showed that hospitalization rates for diarrhea in children younger than five years reduced with the presence of low-risk clusters in Mato Grosso in the final years of the study. Public health surveillance should incorporate spatial analysis to investigate the diarrhea-related morbidity. Objective Brazil 201 2020 Methods SystemUnified System Unified 5 99 replications 13315 13 315 13,31 diarrheaassociated 5yearold yearold old recorded 850 8 50 8.5 3451000 3 45 1 000 3.45/1,00 499 4 4.9 157 57 1.5 14 1– significant Northeast macroregions macro regions Conclusion lowrisk low diarrhearelated morbidity 20 202 9 1331 31 13,3 85 8. 345100 00 3.45/1,0 49 4. 15 1. 2 133 13, 34510 0 3.45/1, 3451 3.45/1 345 3.45/ 34 3.45 3.4 3.
3.
Heritability and genetics correlations for body weight in escargots
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Freitas, Felipe André Oliveira
; Carrara, Eula Regina
; Ladeira, Giovanni
; Lourenço, Matheus
; Leôncio, Thamires
; Miranda, Claudiana
; César, Fernanda Larissa
; Gaya, Leila de Genova
.
ABSTRACT. The objective of this study was to estimate genetic parameters for body weight at 60 (P60), 90 (P90), and 120 (P120) days of age in escargots of the subspecies Cornu aspersum maximum, evaluating the influence of fixed and covariable effects on these traits. The data used were collected from escargots kept in a total confinement system. The significant fixed effects and covariates for these traits were tested in a general linear model by the F-test, considering a level of significance of 5%. Both the fixed effects of box and birth year and the quadratic effect of age of weighing as a covariate were significant (p < 0.05) for P60, P90, and P120. The Restricted Maximum Likelihood (REML) methodology was used to estimate (co)variance components and genetic parameters. High heritability for P60, P90, and P120 (0.38, 0.55 and 0.78, respectively) and high genetic correlations (0.58 to 0.77) among the traits were observed. The genetic parameters can be used as a basis for studies and practical applications to increase zootechnical indexes in this population. ABSTRACT 6 P60 P , (P60) 9 P90 (P90) 12 (P120 maximum system Ftest, Ftest F test, test F-test 5 5% p 0.05 005 0 05 REML (REML covariance co variance P12 0.38, 038 38 (0.38 055 55 0.5 078 78 0.78 respectively 0.58 058 58 (0.5 0.77 077 77 observed population P6 (P60 P9 (P90 1 (P12 0.0 00 P1 0.38 03 3 (0.3 0. 07 7 0.7 (0. (P6 (P9 (P1 0.3 (0 (P (
4.
IMPACTO-MR: um estudo brasileiro de plataforma nacional para avaliar infecções e multirresistência em unidades de terapia intensiva IMPACTOMR IMPACTO MR IMPACTO-MR
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Tomazini, Bruno M
; Nassar Jr, Antonio Paulo
; Lisboa, Thiago Costa
; Azevedo, Luciano César Pontes de
; Veiga, Viviane Cordeiro
; Catarino, Daniela Ghidetti Mangas
; Fogazzi, Debora Vacaro
; Arns, Beatriz
; Piastrelli, Filipe Teixeira
; Dietrich, Camila
; Negrelli, Karina Leal
; Jesuíno, Isabella de Andrade
; Reis, Luiz Fernando Lima
; Mattos, Renata Rodrigues de
; Pinheiro, Carla Cristina Gomes
; Luz, Mariane Nascimento
; Spadoni, Clayse Carla da Silva
; Moro, Elisângela Emilene
; Bueno, Flávia Regina
; Sampaio, Camila Santana Justo Cintra
; Silva, Débora Patrício
; Baldassare, Franca Pellison
; Silva, Ana Cecilia Alcantara
; Veiga, Thabata
; Barbante, Leticia
; Lambauer, Marianne
; Campos, Viviane Bezerra
; Santos, Elton
; Santos, Renato Hideo Nakawaga
; Laranjeiras, Ligia Nasi
; Valeis, Nanci
; Santucci, Eliana
; Miranda, Tamiris Abait
; Patrocínio, Ana Cristina Lagoeiro do
; Carvalho, Andréa de
; Sousa, Eduvirgens Maria Couto de
; Sousa, Ancelmo Honorato Ferraz de
; Malheiro, Daniel Tavares
; Bezerra, Isabella Lott
; Rodrigues, Mirian Batista
; Malicia, Julliana Chicuta
; Silva, Sabrina Souza da
; Gimenes, Bruna dos Passos
; Sesin, Guilhermo Prates
; Zavascki, Alexandre Prehn
; Sganzerla, Daniel
; Medeiros, Gregory Saraiva
; Santos, Rosa da Rosa Minho dos
; Silva, Fernanda Kelly Romeiro
; Cheno, Maysa Yukari
; Abrahão, Carolinne Ferreira
; Oliveira Junior, Haliton Alves de
; Rocha, Leonardo Lima
; Nunes Neto, Pedro Aniceto
; Pereira, Valéria Chagas
; Paciência, Luis Eduardo Miranda
; Bueno, Elaine Silva
; Caser, Eliana Bernadete
; Ribeiro, Larissa Zuqui
; Fernandes, Caio Cesar Ferreira
; Garcia, Juliana Mazzei
; Silva, Vanildes de Fátima Fernandes
; Santos, Alisson Junior dos
; Machado, Flávia Ribeiro
; Souza, Maria Aparecida de
; Ferronato, Bianca Ramos
; Urbano, Hugo Corrêa de Andrade
; Moreira, Danielle Conceição Aparecida
; Souza-Dantas, Vicente Cés de
; Duarte, Diego Meireles
; Coelho, Juliana
; Figueiredo, Rodrigo Cruvinel
; Foreque, Fernanda
; Romano, Thiago Gomes
; Cubos, Daniel
; Spirale, Vladimir Miguel
; Nogueira, Roberta Schiavon
; Maia, Israel Silva
; Zandonai, Cassio Luis
; Lovato, Wilson José
; Cerantola, Rodrigo Barbosa
; Toledo, Tatiana Gozzi Pancev
; Tomba, Pablo Oscar
; Almeida, Joyce Ramos de
; Sanches, Luciana Coelho
; Pierini, Leticia
; Cunha, Mariana
; Sousa, Michelle Tereza
; Azevedo, Bruna
; Dal-Pizzol, Felipe
; Damasio, Danusa de Castro
; Bainy, Marina Peres
; Beduhn, Dagoberta Alves Vieira
; Jatobá, Joana D’Arc Vila Nova
; Moura, Maria Tereza Farias de
; Rego, Leila Rezegue de Moraes
; Silva, Adria Vanessa da
; Oliveira, Luana Pontes
; Sodré Filho, Eliene Sá
; Santos, Silvana Soares dos
; Neves, Itallo de Lima
; Leão, Vanessa Cristina de Aquino
; Paes, João Lucidio Lobato
; Silva, Marielle Cristina Mendes
; Oliveira, Cláudio Dornas de
; Santiago, Raquel Caldeira Brant
; Paranhos, Jorge Luiz da Rocha
; Wiermann, Iany Grinezia da Silva
; Pedroso, Durval Ferreira Fonseca
; Sawada, Priscilla Yoshiko
; Prestes, Rejane Martins
; Nascimento, Glícia Cardoso
; Grion, Cintia Magalhães Carvalho
; Carrilho, Claudia Maria Dantas de Maio
; Dantas, Roberta Lacerda Almeida de Miranda
; Silva, Eliane Pereira
; Silva, Antônio Carlos da
; Oliveira, Sheila Mara Bezerra de
; Golin, Nicole Alberti
; Tregnago, Rogerio
; Lima, Valéria Paes
; Silva, Kamilla Grasielle Nunes da
; Boschi, Emerson
; Buffon, Viviane
; Machado, André Sant’Ana
; Capeletti, Leticia
; Foernges, Rafael Botelho
; Carvalho, Andréia Schubert de
; Oliveira Junior, Lúcio Couto de
; Oliveira, Daniela Cunha de
; Silva, Everton Macêdo
; Ribeiro, Julival
; Pereira, Francielle Constantino
; Salgado, Fernanda Borges
; Deutschendorf, Caroline
; Silva, Cristofer Farias da
; Gobatto, Andre Luiz Nunes
; Oliveira, Carolaine Bomfim de
; Dracoulakis, Marianna Deway Andrade
; Alvaia, Natália Oliveira Santos
; Souza, Roberta Machado de
; Araújo, Larissa Liz Cardoso de
; Melo, Rodrigo Morel Vieira de
; Passos, Luiz Carlos Santana
; Vidal, Claudia Fernanda de Lacerda
; Rodrigues, Fernanda Lopes de Albuquerque
; Kurtz, Pedro
; Shinotsuka, Cássia Righy
; Tavares, Maria Brandão
; Santana, Igor das Virgens
; Gavinho, Luciana Macedo da Silva
; Nascimento, Alaís Brito
; Pereira, Adriano J
; Cavalcanti, Alexandre Biasi
.
RESUMO Objetivo: Descrever o IMPACTO-MR, um estudo brasileiro de plataforma nacional em unidades de terapia intensiva focado no impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Métodos: Descrevemos a plataforma IMPACTO-MR, seu desenvolvimento, critérios para seleção das unidades de terapia intensiva, caracterização da coleta de dados, objetivos e projetos de pesquisa futuros a serem realizados na plataforma. Resultados: Os dados principais foram coletados por meio do Epimed Monitor System® e consistiram em dados demográficos, dados de comorbidades, estado funcional, escores clínicos, diagnóstico de internação e diagnósticos secundários, dados laboratoriais, clínicos e microbiológicos e suporte de órgãos durante a internação na unidade de terapia intensiva, entre outros. De outubro de 2019 a dezembro de 2020, 33.983 pacientes de 51 unidades de terapia intensiva foram incluídos no banco de dados principal. Conclusão: A plataforma IMPACTO-MR é um banco de dados clínico brasileiro de unidades de terapia intensiva focado na pesquisa do impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Essa plataforma fornece dados para o desenvolvimento e pesquisa de unidades de terapia intensiva individuais e ensaios clínicos observacionais e prospectivos multicêntricos. Objetivo IMPACTOMR, IMPACTOMR IMPACTO MR, MR saúde Métodos Resultados System demográficos comorbidades funcional secundários laboratoriais outros 201 2020 33983 33 983 33.98 5 principal Conclusão multicêntricos 20 202 3398 3 98 33.9 2 339 9 33.
ABSTRACT Objective: To describe the IMPACTO-MR, a Brazilian nationwide intensive care unit platform study focused on the impact of health care-associated infections due to multidrug-resistant bacteria. Methods: We described the IMPACTO-MR platform, its development, criteria for intensive care unit selection, characterization of core data collection, objectives, and future research projects to be held within the platform. Results: The core data were collected using the Epimed Monitor System® and consisted of demographic data, comorbidity data, functional status, clinical scores, admission diagnosis and secondary diagnoses, laboratory, clinical, and microbiological data, and organ support during intensive care unit stay, among others. From October 2019 to December 2020, 33,983 patients from 51 intensive care units were included in the core database. Conclusion: The IMPACTO-MR platform is a nationwide Brazilian intensive care unit clinical database focused on researching the impact of health care-associated infections due to multidrug-resistant bacteria. This platform provides data for individual intensive care unit development and research and multicenter observational and prospective trials. Objective IMPACTOMR, IMPACTOMR IMPACTO MR, MR careassociated associated multidrugresistant multidrug resistant bacteria Methods selection collection objectives Results System status scores diagnoses laboratory stay others 201 2020 33983 33 983 33,98 5 Conclusion trials 20 202 3398 3 98 33,9 2 339 9 33,
5.
Differences in children and adolescents with SARS-CoV-2 infection: a cohort study in a Brazilian tertiary referral hospital
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Marques, Heloisa Helena de Sousa
; Pereira, Maria Fernanda Badue
; Santos, Angélica Carreira dos
; Fink, Thais Toledo
; Paula, Camila Sanson Yoshino de
; Litvinov, Nadia
; Schvartsman, Claudio
; Delgado, Artur Figueiredo
; Gibelli, Maria Augusta Bento Cicaroni
; Carvalho, Werther Brunow de
; Odone Filho, Vicente
; Tannuri, Uenis
; Carneiro-Sampaio, Magda
; Grisi, Sandra
; Duarte, Alberto José da Silva
; Antonangelo, Leila
; Francisco, Rossana Pucineli Vieira
; Okay, Thelma Suely
; Batisttella, Linamara Rizzo
; Carvalho, Carlos Roberto Ribeiro de
; Brentani, Alexandra Valéria Maria
; Silva, Clovis Artur
; Eisencraft, Adriana Pasmanik
; Rossi Junior, Alfio
; Fante, Alice Lima
; Cora, Aline Pivetta
; Reis, Amelia Gorete A. de Costa
; Ferrer, Ana Paula Scoleze
; Andrade, Anarella Penha Meirelles de
; Watanabe, Andreia
; Gonçalves, Angelina Maria Freire
; Waetge, Aurora Rosaria Pagliara
; Silva, Camila Altenfelder
; Ceneviva, Carina
; Lazari, Carolina dos Santos
; Abellan, Deipara Monteiro
; Santos, Emilly Henrique dos
; Sabino, Ester Cerdeira
; Bianchini, Fabíola Roberta Marim
; Alcantara, Flávio Ferraz de Paes
; Ramos, Gabriel Frizzo
; Leal, Gabriela Nunes
; Rodriguez, Isadora Souza
; Pinho, João Renato Rebello
; Carneiro, Jorge David Avaizoglou
; Paz, Jose Albino
; Ferreira, Juliana Carvalho
; Ferranti, Juliana Ferreira
; Ferreira, Juliana de Oliveira Achili
; Framil, Juliana Valéria de Souza
; Silva, Katia Regina da
; Kanunfre, Kelly Aparecida
; Bastos, Karina Lucio de Medeiros
; Galleti, Karine Vusberg
; Cristofani, Lilian Maria
; Suzuki, Lisa
; Campos, Lucia Maria Arruda
; Perondi, Maria Beatriz de Moliterno
; Diniz, Maria de Fatima Rodrigues
; Fonseca, Maria Fernanda Mota
; Cordon, Mariana Nutti de Almeida
; Pissolato, Mariana
; Peres, Marina Silva
; Garanito, Marlene Pereira
; Imamura, Marta
; Dorna, Mayra de Barros
; Luglio, Michele
; Rocha, Mussya Cisotto
; Aikawa, Nadia Emi
; Degaspare, Natalia Viu
; Sakita, Neusa Keico
; Udsen, Nicole Lee
; Scudeller, Paula Gobi
; Gaiolla, Paula Vieira de Vincenzi
; Severini, Rafael da Silva Giannasi
; Rodrigues, Regina Maria
; Toma, Ricardo Katsuya
; Paula, Ricardo Iunis Citrangulo de
; Palmeira, Patricia
; Forsait, Silvana
; Farhat, Sylvia Costa Lima
; Sakano, Tânia Miyuki Shimoda
; Koch, Vera Hermina Kalika
; Cobello Junior, Vilson
.
OBJECTIVES: To compare demographic/clinical/laboratory/treatments and outcomes among children and adolescents with laboratory-confirmed coronavirus disease 2019 (COVID-19). METHODS: This was a cross-sectional study that included patients diagnosed with pediatric COVID-19 (aged <18 years) between April 11, 2020 and April 22, 2021. During this period, 102/5,951 (1.7%) of all admissions occurred in neonates, children, and adolescents. Furthermore, 3,962 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection samples were processed in patients aged <18 years, and laboratory-confirmed COVID-19 occurred in 155 (4%) inpatients and outpatients. Six/155 pediatric patients were excluded from the study. Therefore, the final group included 149 children and adolescents (n=97 inpatients and 52 outpatients) with positive SARS-CoV-2 results. RESULTS: The frequencies of sore throat, anosmia, dysgeusia, headache, myalgia, nausea, lymphopenia, pre-existing chronic conditions, immunosuppressive conditions, and autoimmune diseases were significantly reduced in children and adolescents (p<0.05). Likewise, the frequencies of enoxaparin use (p=0.037), current immunosuppressant use (p=0.008), vasoactive agents (p=0.045), arterial hypotension (p<0.001), and shock (p=0.024) were significantly lower in children than in adolescents. Logistic regression analysis showed that adolescents with laboratory-confirmed COVID-19 had increased odds ratios (ORs) for sore throat (OR 13.054; 95% confidence interval [CI] 2.750-61.977; p=0.001), nausea (OR 8.875; 95% CI 1.660-47.446; p=0.011), and lymphopenia (OR 3.575; 95% CI 1.355-9.430; p=0.010), but also had less hospitalizations (OR 0.355; 95% CI 0.138-0.916; p=0.032). The additional logistic regression analysis on patients with preexisting chronic conditions (n=108) showed that death as an outcome was significantly associated with pediatric severe acute respiratory syndrome (SARS) (OR 22.300; 95% CI 2.341-212.421; p=0.007) and multisystem inflammatory syndrome in children (MIS-C) (OR 11.261; 95% CI 1.189-106. 581; p=0.035). CONCLUSIONS: Half of the laboratory-confirmed COVID-19 cases occurred in adolescents. Individuals belonging to this age group had an acute systemic involvement of SARS-CoV-2 infection. Pediatric SARS and MIS-C were the most important factors associated with the mortality rate in pediatric chronic conditions with COVID-19.
6.
Posicionamento da Sociedade Brasileira de Cardiologia para Gravidez e Planejamento Familiar na Mulher Portadora de Cardiopatia – 2020
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Avila, Walkiria Samuel
; Alexandre, Elizabeth Regina Giunco
; Castro, Marildes Luiza de
; Lucena, Alexandre Jorge Gomes de
; Marques-Santos, Celi
; Freire, Claudia Maria Vilas
; Rossi, Eduardo Giusti
; Campanharo, Felipe Favorette
; Rivera, Ivan Romero
; Costa, Maria Elizabeth Navegantes Caetano
; Rivera, Maria Alayde Mendonça
; Carvalho, Regina Coeli Marques de
; Abzaid, Alexandre
; Moron, Antonio Fernandes
; Ramos, Auristela Isabel de Oliveira
; Albuquerque, Carlos Japhet da Mata
; Feio, Claudine Maia Alves
; Born, Daniel
; Silva, Fábio Bruno da
; Nani, Fernando Souza
; Tarasoutchi, Flavio
; Costa Junior, José de Ribamar
; Melo Filho, José Xavier de
; Katz, Leila
; Almeida, Maria Cristina Costa
; Grinberg, Max
; Amorim, Melania Maria Ramos de
; Melo, Nilson Roberto de
; Medeiros, Orlando Otávio de
; Pomerantzeff, Pablo Maria Alberto
; Braga, Sérgio Luiz Navarro
; Cristino, Sonia Conde
; Martinez, Tania Leme da Rocha
; Leal, Tatiana de Carvalho Andreuci Torres
.
https://doi.org/10.36660/abc.20200406
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7.
Colonization profile and duration by multi-resistant organisms in a prospective cohort of newborns after hospital discharge
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Sakai, Andressa Midori
; Iensue, Thayla Nadrielly Aparecida Nicolino
; Pereira, Kauana Olanda
; Silva, Renata Lima da
; Pegoraro, Leila Garcia de Oliveira
; Salvador, Marta Silva de Almeida
; Rodrigues, Renne
; Capobiango, Jaqueline Dario
; Souza, Nathália Aparecida Andrade de
; Pelisson, Marsileni
; Vespero, Eliana Carolina
; Yamauchi, Lucy Megumi
; Perugini, Marcia Regina Eches
; Yamada-Ogatta, Sueli Fumie
; Rossetto, Edilaine Giovanini
; Kerbauy, Gilselena
.
Revista do Instituto de Medicina Tropical de São Paulo
- Journal Metrics
ABSTRACT The aim of this study was to determine the spontaneous decolonization period and characteristics in a prospective cohort of newborns colonized by multidrug-resistant organisms, after their discharge from the neonatal intensive care unit. Multidrug resistance is defined as bacterial non-susceptibility to ≥ 1 agent of ≥ 3 antimicrobial categories. In total, 618 newborns were included in the study, of which 173 (28.0%) presented a positive culture for multidrug-resistant microorganisms, and of these, 52 (30.1%) were followed up in this study. The most frequent intrinsic factors were be born by cesarean section (86.5%), prematurity (84.6%), and very low birth weight (76.9%). The extrinsic factors were having remained hospitalized for an average of 27 days, during which 67.3% were submitted to invasive procedures and 88.5% received antimicrobials. The intrinsic and extrinsic factors of newborns were not associated to a decolonization period longer or shorter than 3 months, which was the average period of decolonization found in the present study. From the totality of colonization cultures sampled at hospital discharge, the Gram-negative Extended Spectrum β-lactamase producing bacteria were the most common, with 28.9% of babies colonized by Klebsiella spp. The median period of decolonization by multidrug-resistant microorganisms in the newborns population after hospital discharge was 3 months, but was highly dependent on the microbial species, and this period was not associated to any intrinsic and extrinsic factors of the newborn.
https://doi.org/10.1590/s1678-9946202062022
899 downloads
8.
Syphilis in pregnant women and congenital syphilis: spatial pattern and relationship with social determinants of health in Mato Grosso
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Revista da Sociedade Brasileira de Medicina Tropical
- Journal Metrics
Abstract INTRODUCTION: The increasing incidence of syphilis among pregnant women (PS) and congenital syphilis (CS) has negatively affected maternal-child health in Brazil. The spatial approach to diseases with social indicators improves knowledge of health situations. Herein, we aimed to evaluate the spatiotemporal distribution of incidences, identify the priority areas for infection control actions, and analyze the relationship of PS and CS clusters with social determinants of health in Mato Grosso. METHODS: This is an ecological study with data from different health information systems. After data procedure linkage, we analyzed the Bayesian incidences of triennial infections during specific periods. We performed SATSCAN screenings to identify spatiotemporal clusters. Further, we verified the differences between the clusters and indicators using Pearson’s chi-square test. RESULTS: The variations in PS incidence were 0.9-20.5/1,000 live births (LB), 0.6-46.3/1,000 LB, and 2.1-23.2/1,000 LB in the first, second, and last triennium, respectively; for CS, the variations were 0-7.1/1,000 LB, 0-7.5/1,000 LB, and 0.3-10.8/1,000 LB in the first, second, and last triennium, respectively. Three clusters each were identified for PS (RR=2.02; RR=0.30; RR=21.45, p<0.0001) and CS (RR=3.55; RR=0.10; RR=0.26, p<0.0001). The high-risk clusters overlapped in time-space; CS incidence was associated with municipalities with a higher proportion of LB mothers of race/non-white color and with poor sanitary conditions, lower proportion of pregnant teenagers, and under 8 years of schooling. CONCLUSIONS: The increase in the spatiotemporal evolution of PS and CS incidences and the extension of areas with persistent infections indicate the need for monitoring, especially of priority areas in the state.
https://doi.org/10.1590/0037-8682-0316-2020
456 downloads
9.
Visceral composition, carcass yield and meat quality parameters of free-range broilers with diets containing different levels of crushed sugarcane
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RESENDE, Viviane Assunção de
; TEIXEIRA, Alexandre de Oliveira
; MOREIRA, Leonardo Marmo
; CORASSA, Anderson
; PIRES, Christiano Vieira
; VALENTE JÚNIOR, Dante Teixeira
; VIDIGAL, Márcia Cristina Teixeira Ribeiro
; GAYA, Leila de Genova
; BRIGHENTI, Carla Regina Guimarães
.
RESUMO Objetivou-se com este trabalho avaliar a composição visceral, o rendimento de cortes e a qualidade de carne de duas linhagens de frangos tipo caipira alimentados com dietas contendo cana-de-açúcar triturada. Foram utilizados 448 frangos distribuídos, aos 35 dias de idade, em dois blocos casualizados, em esquema fatorial 4x2, sendo quatro níveis de substituição da ração (0; 15; 30 e 45%) por de cana-de-açúcar e duas linhagens (Pesadão e Label Rouge), em duas repetições por bloco de quatorze aves unidade experimental. Em 30 minutos após o abate, o parâmetro a* foi maior para os animais da linhagem Pesadão em relação à linhagem Label Rouge. Observou-se efeito quadrático com o aumento dos níveis cana-de-açúcar sobre o parâmetro L* da carne do peito; e efeito linear sobre o parâmetro b* da pele do peito. Em 24 horas após o abate, observou-se efeito quadrático dos níveis de cana-de-açúcar sobre o parâmetro b* da carne do peito. O aumento dos níveis de cana-de-açúcar reduziu linearmente o peso do coração, fígado, peito, coxa mais sobrecoxa, asa, rendimento de carcaça e peso relativo do coração dos animais. Observou-se efeito quadrático com o aumento dos níveis de cana-de-açúcar sobre o peso relativo da gordura abdominal, sendo que o menor teor de gordura foi observado nos animais que consumiram até 30% de cana-de-açúcar. O uso da cana-de-açúcar como alimento alternativo em até 45% na dieta, possibilita manter a qualidade de carne e reduz o teor de gordura abdominal, porém, diminui o rendimento de carcaça.
ABSTRACT The aim of this study was to evaluate the visceral composition, cuts, and meat quality of two strains of free-range chickens fed diets containing crushed sugar cane. 448 chickens were distributed at 35 days of age, in two randomized blocks design, in 4x2 factorial, with four levels of replacement in the feed (0; 15; 30 and 45%) by sugarcane and two strains (Pesadão and Label Rouge), in two repetitions per block of fourteen birds per experimental unit. In 30 minutes after slaughter, the parameter a* was higher for animals of the Pesadão strain relation to the Label Rouge lineage. A quadratic effect was observed with increasing levels of sugarcane on the L* parameter of breast meat; and linear effect on parameter b* of the breast skin. Within 24 hours after slaughter, a quadratic effect of sugarcane levels was observed on the b* parameter of the breast meat. The increase in sugarcane levels linearly reduced the weight of heart, liver, chest, thigh plus drumstick, wing, carcass yield and relative heart weight of the animals. A quadratic effect was observed with increase in sugarcane levels over the relative weight of abdominal fat, the lowest fat content was observed in animals that consumed up to 30% of sugarcane in the feed. The use of sugarcane as an alternative feedstuff in up to 45% in the diet maintains the quality of meat and reduces the abdominal fat content, however, decreases the carcass yield.
https://doi.org/10.1590/s1519-99402121162020
585 downloads
10.
Characteristics and outcomes of patients with COVID-19 admitted to the ICU in a university hospital in São Paulo, Brazil - study protocol
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Ferreira, Juliana C.
; Ho, Yeh-Li
; Besen, Bruno A.M.P.
; Malbuisson, Luiz M.S.
; Taniguchi, Leandro U.
; Mendes, Pedro V.
; Costa, Eduardo L.V.
; Park, Marcelo
; Daltro-Oliveira, Renato
; Roepke, Roberta M.L.
; Silva Jr, João M.
; Carmona, Maria José C.
; Carvalho, Carlos Roberto Ribeiro
; Hirota, Adriana
; Kanasiro, Alberto Kendy
; Crescenzi, Alessandra
; Fernandes, Amanda Coelho
; Miethke-Morais, Anna
; Bellintani, Arthur Petrillo
; Canasiro, Artur Ribeiro
; Carneiro, Bárbara Vieira
; Zanbon, Beatriz Keiko
; Batista, Bernardo Pinheiro De Senna Nogueira
; Nicolao, Bianca Ruiz
; Besen, Bruno Adler Maccagnan Pinheiro
; Biselli, Bruno
; Macedo, Bruno Rocha De
; Toledo, Caio Machado Gomes De
; Pompilio, Carlos Eduardo
; Carvalho, Carlos Roberto Ribeiro De
; Mol, Caroline Gomes
; Stipanich, Cassio
; Bueno, Caue Gasparotto
; Garzillo, Cibele
; Tanaka, Clarice
; Forte, Daniel Neves
; Joelsons, Daniel
; Robira, Daniele
; Costa, Eduardo Leite Vieira
; Silva Júnior, Elson Mendes Da
; Regalio, Fabiane Aliotti
; Segura, Gabriela Cardoso
; Marcelino, Gustavo Brasil
; Louro, Giulia Sefrin
; Ho, Yeh-Li
; Ferreira, Isabela Argollo
; Gois, Jeison de Oliveira
; Silva Junior, Joao Manoel Da
; Reusing Junior, Jose Otto
; Ribeiro, Julia Fray
; Ferreira, Juliana Carvalho
; Galleti, Karine Vusberg
; Silva, Katia Regina
; Isensee, Larissa Padrao
; Oliveira, Larissa dos Santos
; Taniguchi, Leandro Utino
; Letaif, Leila Suemi
; Lima, Lígia Trombetta
; Park, Lucas Yongsoo
; Chaves Netto, Lucas
; Nobrega, Luciana Cassimiro
; Haddad, Luciana
; Hajjar, Ludhmila
; Malbouisson, Luiz Marcelo
; Pandolfi, Manuela Cristina Adsuara
; Park, Marcelo
; Carmona, Maria José Carvalho
; Andrade, Maria Castilho Prandini H De
; Santos, Mariana Moreira
; Bateloche, Matheus Pereira
; Suiama, Mayra Akimi
; Oliveira, Mayron Faria de
; Sousa, Mayson Laercio
; Louvaes, Michelle
; Huemer, Natassja
; Mendes, Pedro
; Lins, Paulo Ricardo Gessolo
; Santos, Pedro Gaspar Dos
; Moreira, Pedro Ferreira Paiva
; Guazzelli, Renata Mello
; Reis, Renato Batista Dos
; Oliveira, Renato Daltro De
; Roepke, Roberta Muriel Longo
; Pedro, Rodolpho Augusto De Moura
; Kondo, Rodrigo
; Rached, Samia Zahi
; Fonseca, Sergio Roberto Silveira Da
; Borges, Thais Sousa
; Ferreira, Thalissa
; Cobello Junior, Vilson
; Sales, Vivian Vieira Tenório
; Ferreira, Willaby Serafim Cassa
.
OBJECTIVES: We designed a cohort study to describe characteristics and outcomes of patients with coronavirus disease (COVID-19) admitted to the intensive care unit (ICU) in the largest public hospital in Sao Paulo, Brazil, as Latin America becomes the epicenter of the pandemic. METHODS: This is the protocol for a study being conducted at an academic hospital in Brazil with 300 adult ICU beds dedicated to COVID-19 patients. We will include adult patients admitted to the ICU with suspected or confirmed COVID-19 during the study period. The main outcome is ICU survival at 28 days. Data will be collected prospectively and retrospectively by trained investigators from the hospital’s electronic medical records, using an electronic data capture tool. We will collect data on demographics, comorbidities, severity of disease, and laboratorial test results at admission. Information on the need for advanced life support and ventilator parameters will be collected during ICU stay. Patients will be followed up for 28 days in the ICU and 60 days in the hospital. We will plot Kaplan-Meier curves to estimate ICU and hospital survival and perform survival analysis using the Cox proportional hazards model to identify the main risk factors for mortality. ClinicalTrials.gov: NCT04378582. RESULTS: We expect to include a large sample of patients with COVID-19 admitted to the ICU and to be able to provide data on admission characteristics, use of advanced life support, ICU survival at 28 days, and hospital survival at 60 days. CONCLUSIONS: This study will provide epidemiological data about critically ill patients with COVID-19 in Brazil, which could inform health policy and resource allocation in low- and middle-income countries.
https://doi.org/10.6061/clinics/2020/e2294
1957 downloads
11.
Mosquito (Diptera: Culicidae) fauna in parks in greater São Paulo, Brazil
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Paula, Marcia Bicudo de
; Fernandes, Aristides
; Medeiros-Sousa, Antônio Ralph
; Ceretti-Júnior, Walter
; Christe, Rafael
; Stroebel, Regina Claudia
; Pedrosa, Leila
; Almeida, Rosa Maria Marques de Sá
; Carvalho, Gabriela Cristina de
; Pereira, Uellinton Damasceno
; Jacintho, Marcelo Cassiano de Oliveira
; Natal, Delsio
; Marrelli, Mauro Toledo
.
Em São Paulo os parques municipais preservam resquícios da vegetação de Mata Atlântica, comportam lagos e nascentes, servem de abrigos para mamíferos, aves e artrópodes vetores. São frequentados pela população humana como ambientes de lazer. A zona Leste da cidade possui o maior índice populacional de habitantes e 24 parques municipais. O objetivo deste trabalho foi conhecer a fauna de Culicidae de dois parques da zona Leste da cidade e avaliar a presença de espécies potencialmente bioindicadoras e vetoras de patógenos ao homem. Foram feitas coletas mensais de culicídeos entre março de 2011 a fevereiro de 2012 no Parque do Carmo e no Parque Chico Mendes, com aspiradores elétricos, armadilhas de Shannon e CDC para mosquitos adultos e concha entomológica e bombas manuais de sucção para os imaturos. Para verificar a suficiência amostral foram construídas curvas de acúmulo de espécies por amostragem e a riqueza total foi estimada pelo método Jackknife 1, ambos gerados pelo programa EstimateS. No parque do Carmo foram coletados 1.092 culicídeos, distribuídos em nove gêneros (Aedes, Anopheles, Coquillettidia, Culex, Limatus, Mansonia, Trichoprosopon, Toxorhynchites e Uranotaenia), distribuídos em 19 unidades taxonômicas. Coquillettidia venezuelensis(Theobald 1912), Aedes scapularis (Rondani 1848)e Culex (Culex) spp. Linnaeus 1758 foram os adultos mais abundantes e Culex (Melanoconion) spp. Theobald 1903 e Anopheles strodei Root 1926 os imaturos. No Parque Chico Mendes obteve-se 4.487 mosquitos, distribuídos em seis gêneros e 18 unidades taxonômicas. Culex (Cux.) spp. e Ae. scapularis foram os mais abundantes dos adultos e Ae. albopictus (Skuse 1984) dos imaturos. As curvas de acúmulo de espécies por amostragem em ambos os parques chegaram próximas è assíntota e a estimativa de riqueza total mostrou-se próxima è riqueza observada. Alguns táxons de culicídeos são bioindicadores das condições ambientais dos locais onde vivem, portanto é necessário acompanhar a fauna nativa dos parques municipais porque várias espécies encontradas têm mostrado competência e capacidade para veicular patógenos e arbovírus.
Municipal parks in the city of São Paulo, which are used for leisure purposes, contain remnants of the flora of the Atlantic Forest, as well as lakes and springs, and are home to mammals, birds and arthropods, some of which can be vectors of disease. The eastern side of the city has the largest population in São Paulo and twenty-four municipal parks. The aim of this study was to investigate Culicidae fauna in two parks on this side of the city and to determine which of the Culicidae species identified have the potential to act as bioindicators and vectors of human pathogens. Culicidae were collected monthly between March 2011 and February 2012 in Carmo Park and Chico Mendes Park with battery-powered aspirators, Shannon traps and CDC traps for adult mosquitoes, and larval dippers and suction samplers for immature mosquitoes. To confirm sample sufficiency, the EstimateS program was used to plot sample-based species accumulation curves and estimate total richness by the Jackknife 1 method. In all, 1,092 culicids from nine genera (Aedes, Anopheles, Coquillettidia, Culex, Limatus, Mansonia, Trichoprosopon, Toxorhynchites and Uranotaenia) and nineteen taxonomic units were collected in Carmo Park. Coquillettidia venezuelensis (Theobald 1912), Aedes scapularis (Rondani 1848) and Culex (Culex) spp. Linnaeus 1758 were the most abundant adults, and Culex (Melanoconion) spp. Theobald 1903 and Anopheles strodei Root 1926 the most abundant immature mosquitoes. In Chico Mendes Park 4,487 mosquitoes in six genera and eighteen taxonomic units were collected. Culex (Cux.) spp. and Ae. scapularis were the most abundant adults, and Ae. albopictus (Skuse 1984) the most abundant immature mosquitoes. The species accumulation curves in both parks were close to the asymptote, and the total richness estimate was close to the observed richness. Some culicid taxons are bioindicators of environmental conditions in the areas they inhabit. It is important to monitor native fauna in municipal parks in São Paulo as various species in this study were found to have vector competence and capacity to transmit pathogens, such as arboviruses.
https://doi.org/10.1590/1676-0611-BN-2014-0026
2342 downloads
12.
Growing knowledge: an overview of Seed Plant diversity in Brazil
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Zappi, Daniela C.
; Filardi, Fabiana L. Ranzato
; Leitman, Paula
; Souza, Vinícius C.
; Walter, Bruno M.T.
; Pirani, José R.
; Morim, Marli P.
; Queiroz, Luciano P.
; Cavalcanti, Taciana B.
; Mansano, Vidal F.
; Forzza, Rafaela C.
; Abreu, Maria C.
; Acevedo-Rodríguez, Pedro
; Agra, Maria F.
; Almeida Jr., Eduardo B.
; Almeida, Gracineide S.S.
; Almeida, Rafael F.
; Alves, Flávio M.
; Alves, Marccus
; Alves-Araujo, Anderson
; Amaral, Maria C.E.
; Amorim, André M.
; Amorim, Bruno
; Andrade, Ivanilza M.
; Andreata, Regina H.P.
; Andrino, Caroline O.
; Anunciação, Elisete A.
; Aona, Lidyanne Y.S.
; Aranguren, Yani
; Aranha Filho, João L.M.
; Araújo, Andrea O.
; Araújo, Ariclenes A.M.
; Araújo, Diogo
; Arbo, María M.
; Assis, Leandro
; Assis, Marta C.
; Assunção, Vivian A.
; Athiê-Souza, Sarah M.
; Azevedo, Cecilia O.
; Baitello, João B.
; Barberena, Felipe F.V.A.
; Barbosa, Maria R.V.
; Barros, Fábio
; Barros, Lucas A.V.
; Barros, Michel J.F.
; Baumgratz, José F.A.
; Bernacci, Luis C.
; Berry, Paul E.
; Bigio, Narcísio C.
; Biral, Leonardo
; Bittrich, Volker
; Borges, Rafael A.X.
; Bortoluzzi, Roseli L.C.
; Bove, Cláudia P.
; Bovini, Massimo G.
; Braga, João M.A.
; Braz, Denise M.
; Bringel Jr., João B.A.
; Bruniera, Carla P.
; Buturi, Camila V.
; Cabral, Elza
; Cabral, Fernanda N.
; Caddah, Mayara K.
; Caires, Claudenir S.
; Calazans, Luana S.B.
; Calió, Maria F.
; Camargo, Rodrigo A.
; Campbell, Lisa
; Canto-Dorow, Thais S.
; Carauta, Jorge P.P.
; Cardiel, José M.
; Cardoso, Domingos B.O.S.
; Cardoso, Leandro J.T.
; Carneiro, Camila R.
; Carneiro, Cláudia E.
; Carneiro-Torres, Daniela S.
; Carrijo, Tatiana T.
; Caruzo, Maria B.R.
; Carvalho, Maria L.S.
; Carvalho-Silva, Micheline
; Castello, Ana C.D.
; Cavalheiro, Larissa
; Cervi, Armando C.
; Chacon, Roberta G.
; Chautems, Alain
; Chiavegatto, Berenice
; Chukr, Nádia S.
; Coelho, Alexa A.O.P.
; Coelho, Marcus A.N.
; Coelho, Rubens L.G.
; Cordeiro, Inês
; Cordula, Elizabeth
; Cornejo, Xavier
; Côrtes, Ana L.A.
; Costa, Andrea F.
; Costa, Fabiane N.
; Costa, Jorge A.S.
; Costa, Leila C.
; Costa-e-Silva, Maria B.
; Costa-Lima, James L.
; Cota, Maria R.C.
; Couto, Ricardo S.
; Daly, Douglas C.
; De Stefano, Rodrigo D.
; De Toni, Karen
; Dematteis, Massimiliano
; Dettke, Greta A.
; Di Maio, Fernando R.
; Dórea, Marcos C.
; Duarte, Marília C.
; Dutilh, Julie H.A.
; Dutra, Valquíria F.
; Echternacht, Lívia
; Eggers, Lilian
; Esteves, Gerleni
; Ezcurra, Cecilia
; Falcão Junior, Marcus J.A.
; Feres, Fabíola
; Fernandes, José M.
; Ferreira, D.M.C.
; Ferreira, Fabrício M.
; Ferreira, Gabriel E.
; Ferreira, Priscila P.A.
; Ferreira, Silvana C.
; Ferrucci, Maria S.
; Fiaschi, Pedro
; Filgueiras, Tarciso S.
; Firens, Marcela
; Flores, Andreia S.
; Forero, Enrique
; Forster, Wellington
; Fortuna-Perez, Ana P.
; Fortunato, Reneé H.
; Fraga, Cléudio N.
; França, Flávio
; Francener, Augusto
; Freitas, Joelcio
; Freitas, Maria F.
; Fritsch, Peter W.
; Furtado, Samyra G.
; Gaglioti, André L.
; Garcia, Flávia C.P.
; Germano Filho, Pedro
; Giacomin, Leandro
; Gil, André S.B.
; Giulietti, Ana M.
; A.P.Godoy, Silvana
; Goldenberg, Renato
; Gomes da Costa, Géssica A.
; Gomes, Mário
; Gomes-Klein, Vera L.
; Gonçalves, Eduardo Gomes
; Graham, Shirley
; Groppo, Milton
; Guedes, Juliana S.
; Guimarães, Leonardo R.S.
; Guimarães, Paulo J.F.
; Guimarães, Elsie F.
; Gutierrez, Raul
; Harley, Raymond
; Hassemer, Gustavo
; Hattori, Eric K.O.
; Hefler, Sonia M.
; Heiden, Gustavo
; Henderson, Andrew
; Hensold, Nancy
; Hiepko, Paul
; Holanda, Ana S.S.
; Iganci, João R.V.
; Imig, Daniela C.
; Indriunas, Alexandre
; Jacques, Eliane L.
; Jardim, Jomar G.
; Kamer, Hiltje M.
; Kameyama, Cíntia
; Kinoshita, Luiza S.
; Kirizawa, Mizué
; Klitgaard, Bente B.
; Koch, Ingrid
; Koschnitzke, Cristiana
; Krauss, Nathália P.
; Kriebel, Ricardo
; Kuntz, Juliana
; Larocca, João
; Leal, Eduardo S.
; Lewis, Gwilym P.
; Lima, Carla T.
; Lima, Haroldo C.
; Lima, Itamar B.
; Lima, Laíce F.G.
; Lima, Laura C.P.
; Lima, Leticia R.
; Lima, Luís F.P.
; Lima, Rita B.
; Lírio, Elton J.
; Liro, Renata M.
; Lleras, Eduardo
; Lobão, Adriana
; Loeuille, Benoit
; Lohmann, Lúcia G.
; Loiola, Maria I.B.
; Lombardi, Julio A.
; Longhi-Wagner, Hilda M.
; Lopes, Rosana C.
; Lorencini, Tiago S.
; Louzada, Rafael B.
; Lovo, Juliana
; Lozano, Eduardo D.
; Lucas, Eve
; Ludtke, Raquel
; Luz, Christian L.
; Maas, Paul
; Machado, Anderson F.P.
; Macias, Leila
; Maciel, Jefferson R.
; Magenta, Mara A.G.
; Mamede, Maria C.H.
; Manoel, Evelin A.
; Marchioretto, Maria S.
; Marques, Juliana S.
; Marquete, Nilda
; Marquete, Ronaldo
; Martinelli, Gustavo
; Martins da Silva, Regina C.V.
; Martins, Ângela B.
; Martins, Erika R.
; Martins, Márcio L.L.
; Martins, Milena V.
; Martins, Renata C.
; Matias, Ligia Q.
; Maya-L., Carlos A.
; Mayo, Simon
; Mazine, Fiorella
; Medeiros, Debora
; Medeiros, Erika S.
; Medeiros, Herison
; Medeiros, João D.
; Meireles, José E.
; Mello-Silva, Renato
; Melo, Aline
; Melo, André L.
; Melo, Efigênia
; Melo, José I.M.
; Menezes, Cristine G.
; Menini Neto, Luiz
; Mentz, Lilian A.
; Mezzonato, A.C.
; Michelangeli, Fabián A.
; Milward-de-Azevedo, Michaele A.
; Miotto, Silvia T.S.
; Miranda, Vitor F.O.
; Mondin, Cláudio A.
; Monge, Marcelo
; Monteiro, Daniele
; Monteiro, Raquel F.
; Moraes, Marta D.
; Moraes, Pedro L.R.
; Mori, Scott A.
; Mota, Aline C.
; Mota, Nara F.O.
; Moura, Tania M.
; Mulgura, Maria
; Nakajima, Jimi N.
; Nardy, Camila
; Nascimento Júnior, José E.
; Noblick, Larry
; Nunes, Teonildes S.
; O'Leary, Nataly
; Oliveira, Arline S.
; Oliveira, Caetano T.
; Oliveira, Juliana A.
; Oliveira, Luciana S.D.
; Oliveira, Maria L.A.A.
; Oliveira, Regina C.
; Oliveira, Renata S.
; Oliveira, Reyjane P.
; Paixão-Souza, Bruno
; Parra, Lara R.
; Pasini, Eduardo
; Pastore, José F.B.
; Pastore, Mayara
; Paula-Souza, Juliana
; Pederneiras, Leandro C.
; Peixoto, Ariane L.
; Pelissari, Gisela
; Pellegrini, Marco O.O.
; Pennington, Toby
; Perdiz, Ricardo O.
; Pereira, Anna C.M.
; Pereira, Maria S.
; Pereira, Rodrigo A.S.
; Pessoa, Clenia
; Pessoa, Edlley M.
; Pessoa, Maria C.R.
; Pinto, Luiz J.S.
; Pinto, Rafael B.
; Pontes, Tiago A.
; Prance, Ghillean T.
; Proença, Carolyn
; Profice, Sheila R.
; Pscheidt, Allan C.
; Queiroz, George A.
; Queiroz, Rubens T.
; Quinet, Alexandre
; Rainer, Heimo
; Ramos, Eliana
; Rando, Juliana G.
; Rapini, Alessandro
; Reginato, Marcelo
; Reis, Ilka P.
; Reis, Priscila A.
; Ribeiro, André R.O.
; Ribeiro, José E.L.S.
; Riina, Ricarda
; Ritter, Mara R.
; Rivadavia, Fernando
; Rocha, Antônio E.S.
; Rocha, Maria J.R.
; Rodrigues, Izabella M.C.
; Rodrigues, Karina F.
; Rodrigues, Rodrigo S.
; Rodrigues, Rodrigo S.
; Rodrigues, Vinícius T.
; Rodrigues, William
; Romaniuc Neto, Sérgio
; Romão, Gerson O.
; Romero, Rosana
; Roque, Nádia
; Rosa, Patrícia
; Rossi, Lúcia
; Sá, Cyl F.C.
; Saavedra, Mariana M.
; Saka, Mariana
; Sakuragui, Cássia M.
; Salas, Roberto M.
; Sales, Margareth F.
; Salimena, Fatima R.G.
; Sampaio, Daniela
; Sancho, Gisela
; Sano, Paulo T.
; Santos, Alessandra
; Santos, Élide P.
; Santos, Juliana S.
; Santos, Marianna R.
; Santos-Gonçalves, Ana P.
; Santos-Silva, Fernanda
; São-Mateus, Wallace
; Saraiva, Deisy P.
; Saridakis, Dennis P.
; Sartori, Ângela L.B.
; Scalon, Viviane R.
; Schneider, Ângelo
; Sebastiani, Renata
; Secco, Ricardo S.
; Senna, Luisa
; Senna-Valle, Luci
; Shirasuna, Regina T.
; Silva Filho, Pedro J.S.
; Silva, Anádria S.
; Silva, Christian
; Silva, Genilson A.R.
; Silva, Gisele O.
; Silva, Márcia C.R.
; Silva, Marcos J.
; Silva, Marcos J.
; Silva, Otávio L.M.
; Silva, Rafaela A.P.
; Silva, Saura R.
; Silva, Tania R.S.
; Silva-Gonçalves, Kelly C.
; Silva-Luz, Cíntia L.
; Simão-Bianchini, Rosângela
; Simões, André O.
; Simpson, Beryl
; Siniscalchi, Carolina M.
; Siqueira Filho, José A.
; Siqueira, Carlos E.
; Siqueira, Josafá C.
; Smith, Nathan P.
; Snak, Cristiane
; Soares Neto, Raimundo L.
; Soares, Kelen P.
; Soares, Marcos V.B.
; Soares, Maria L.
; Soares, Polyana N.
; Sobral, Marcos
; Sodré, Rodolfo C.
; Somner, Genise V.
; Sothers, Cynthia A.
; Sousa, Danilo J.L.
; Souza, Elnatan B.
; Souza, Élvia R.
; Souza, Marcelo
; Souza, Maria L.D.R.
; Souza-Buturi, Fátima O.
; Spina, Andréa P.
; Stapf, María N.S.
; Stefano, Marina V.
; Stehmann, João R.
; Steinmann, Victor
; Takeuchi, Cátia
; Taylor, Charlotte M.
; Taylor, Nigel P.
; Teles, Aristônio M.
; Temponi, Lívia G.
; Terra-Araujo, Mário H.
; Thode, Veronica
; Thomas, W.Wayt
; Tissot-Squalli, Mara L.
; Torke, Benjamin M.
; Torres, Roseli B.
; Tozzi, Ana M.G.A.
; Trad, Rafaela J.
; Trevisan, Rafael
; Trovó, Marcelo
; Valls, José F.M.
; Vaz, Angela M.S.F.
; Versieux, Leonardo
; Viana, Pedro L.
; Vianna Filho, Marcelo D.M.
; Vieira, Ana O.S.
; Vieira, Diego D.
; Vignoli-Silva, Márcia
; Vilar, Thaisa
; Vinhos, Franklin
; Wallnöfer, Bruno
; Wanderley, Maria G.L.
; Wasshausen, Dieter
; Watanabe, Maurício T.C.
; Weigend, Maximilian
; Welker, Cassiano A.D.
; Woodgyer, Elizabeth
; Xifreda, Cecilia C.
; Yamamoto, Kikyo
; Zanin, Ana
; Zenni, Rafael D.
; Zickel, Carmem S
.
Resumo Um levantamento atualizado das plantas com sementes e análises relevantes acerca desta biodiversidade são apresentados. Este trabalho se iniciou em 2010 com a publicação do Catálogo de Plantas e Fungos e, desde então vem sendo atualizado por mais de 430 especialistas trabalhando online. O Brasil abriga atualmente 32.086 espécies nativas de Angiospermas e 23 espécies nativas de Gimnospermas e estes novos dados mostram um aumento de 3% da riqueza em relação a 2010. A Amazônia é o Domínio Fitogeográfico com o maior número de espécies de Gimnospermas, enquanto que a Floresta Atlântica possui a maior riqueza de Angiospermas. Houve um crescimento considerável no número de espécies e nas taxas de endemismo para a maioria dos Domínios (Caatinga, Cerrado, Floresta Atlântica, Pampa e Pantanal), com exceção da Amazônia que apresentou uma diminuição de 2,5% de endemicidade. Entretanto, a maior parte das plantas com sementes que ocorrem no Brasil (57,4%) é endêmica deste território. A proporção de formas de vida varia de acordo com os diferentes Domínios: árvores são mais expressivas na Amazônia e Floresta Atlântica do que nos outros biomas, ervas são dominantes no Pampa e as lianas apresentam riqueza expressiva na Amazônia, Floresta Atlântica e Pantanal. Este trabalho não só quantifica a biodiversidade brasileira, mas também indica as lacunas de conhecimento e o desafio a ser enfrentado para a conservação desta flora.
Abstract An updated inventory of Brazilian seed plants is presented and offers important insights into the country's biodiversity. This work started in 2010, with the publication of the Plants and Fungi Catalogue, and has been updated since by more than 430 specialists working online. Brazil is home to 32,086 native Angiosperms and 23 native Gymnosperms, showing an increase of 3% in its species richness in relation to 2010. The Amazon Rainforest is the richest Brazilian biome for Gymnosperms, while the Atlantic Rainforest is the richest one for Angiosperms. There was a considerable increment in the number of species and endemism rates for biomes, except for the Amazon that showed a decrease of 2.5% of recorded endemics. However, well over half of Brazillian seed plant species (57.4%) is endemic to this territory. The proportion of life-forms varies among different biomes: trees are more expressive in the Amazon and Atlantic Rainforest biomes while herbs predominate in the Pampa, and lianas are more expressive in the Amazon, Atlantic Rainforest, and Pantanal. This compilation serves not only to quantify Brazilian biodiversity, but also to highlight areas where there information is lacking and to provide a framework for the challenge faced in conserving Brazil's unique and diverse flora.
https://doi.org/10.1590/2175-7860201566411
33340 downloads
13.
Evaluation of preventative and control measures for congenital syphilis in State of Mato Grosso
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Oliveira, Leila Regina de
; Costa, Maria da Conceição Nascimento
; Barreto, Florisneide Rodrigues
; Pereira, Susan Martins
; Dourado, Inês
; Teixeira, Maria Glória
.
Revista da Sociedade Brasileira de Medicina Tropical
- Journal Metrics
Introduction Congenital syphilis is an important health problem in Brazil. This study assessed measures aimed at the prevention and control of syphilis in the State of Mato Grosso and its capital, Cuiabá. Methods A descriptive study cross-sectional and of time trends assessing the congenital syphilis was performed in Cuiabá and Mato Grosso between 2001 and 2011. We compared maternal sociodemographic characteristics and health care utilization related to cases of congenital syphilis during the periods from 2001 to 2006 and from 2007 to 2011. We assessed the temporal trends in this disease's incidence using a simple linear regression. Results Between 2001 and 2006 in Mato Grosso, 86.8% of the mothers who had live births with congenital syphilis received prenatal care, 90.6% presented with a nontreponemal test reagent at delivery, 96.2% had no information regarding a treponemal confirmatory test at delivery, and 77.6% received inadequate treatment for syphilis; additionally, 75.8% of their partners were not treated. There was a statistically significant reduction in prenatal visits (p = 0.004) and an increase in the proportion of mothers reactive to nontreponemal tests at delivery (p = 0.031) between the two periods. No other variables were found to differ significantly between the periods. In Cuiabá, we observed a similar distribution of variables. In the state and in the capital, the increasing trend of congenital syphilis was not statistically significant. Conclusions The high incidence of congenital syphilis in Mato Grosso and the low levels of health care indicators for pregnant women with syphilis suggest the need to improve the coverage and quality of prenatal care.
14.
Prevalência e significância clínica de interações fármaco-nutrição enteral em Unidades de Terapia Intensiva
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Reis, Adriano Max Moreira
; Carvalho, Rhanna Emanuela Fontenele Lima de
; Faria, Leila Marcia Pereira de
; Oliveira, Regina Célia de
; Zago, Karine Santana de Azevedo
; Cavelagna, Milena Ferreira
; Silva, Adriano Gomes
; Neto, Manoel Luis
; Cassiani, Silvia Helena de Bortoli
.
Estudo multicêntrico, transversal e retrospectivo, que objetivou determinar a prevalência de interações fármaco-nutrição enteral (NE) em Unidades de Terapia Intensiva (UTI) de sete hospitais de ensino do Brasil, e analisar a significância clínica das mesmas. Foram coletadas informações sobre medicamentos e NE administrados com 24 horas e 120 horas de internação. Para identificação das interações fármaco-NE empregou-se o software Drug Reax®. Foram investigados 1.124 prontuários. Destes, 320 pacientes, com 24 horas de internação, estavam em uso de NE, sendo que 20 (6,3%) apresentaram interação fármaco-NE. Dos 504 pacientes, com 120 horas de internação, 39 (7,7%) apresentaram interação fármaco-NE. As potenciais interações fármaco-NE mais frequentes foram: fenitoína-NE, levotiroxina-NE e varfarina-NE. As interações fármaco-NE podem interferir na qualidade e no custo da assistência prestada em UTI e, desta forma, é essencial que a equipe de saúde tenha conhecimento sobre as mesmas.
This is a multicenter, cross-sectional retrospective study, which aimed to determine the prevalence of interactions drug-enteral nutrition (EN) in Intensive Care Units (ICU) of seven teaching hospitals in Brazil, and to analyze the clinical significance of them. Information on medications and EN administered with 24 hours and 120 hours of hospitalization were collected. For identification of drug-EN interaction was employed software Drug Reax®. It was investigated 1.124 records. Of these, 320 patients, with 24 hours of hospitalization, were on EN, and 20 (6.3%) had drug-EN interaction. Of the 504 patients with 120 hours of hospitalization, 39 (7.7%) had drug-EN interaction. The most frequent drug-EN interactions of clinical significance were phenytoin-EN, warfarin-EN and levothyroxine-EN. Drug-EN interactions may interfere with the quality and cost effectiveness of care in ICU, so it is essential that the health team has knowledge about them.
Estudio multicéntrico, transversal retrospectivo, que tuvo como objetivo determinar la prevalencia de interacciones drogasnutrición enteral (NE) en Unidades de Cuidados Intensivos (UCI) de siete hospitales de enseñanza en Brasil, y analizar el significado clínico de las mismas. Fueran colectadas informaciones en 24 horas y 120 horas de hospitalización en los registros médicos. Para identificar las interacciones fármaco-NE se utilizó el software de Drug Reax®. Fueran investigados 1.124 registros. De éstos, 320 pacientes, con 24 horas de hospitalización, se encontraban en la NE, 20 (6,3%) presentarán interacción. De los 504 pacientes, con 120 horas de hospitalización, 39 (7,7%) tuvieron la interacción. Las interacciones fármacos-NE más frecuentes fueron: fenitoína-NE, levotiroxina-NE, warfarina-NE. Las interacciones fármacos-NE pueden interferir con la calidad de los cuidados en la UCI, por lo que es esencial que el equipo de salud tenga conocimientos al respecto.
https://doi.org/10.5935/0034-7167.20140011
9458 downloads
15.
Prevalência e significância clínica de interações fármaco-nutrição enteral em Unidades de Terapia Intensiva
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Facebook Twitter
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- Mendeley
- Other networks
- Metrics
Reis, Adriano Max Moreira
; Carvalho, Rhanna Emanuela Fontenele Lima de
; Faria, Leila Marcia Pereira de
; Oliveira, Regina Célia de
; Zago, Karine Santana de Azevedo
; Cavelagna, Milena Ferreira
; Silva, Adriano Gomes
; Neto, Manoel Luis
; Cassiani, Silvia Helena de Bortoli
.
This is a multicenter, cross-sectional retrospective study, which aimed to determine the prevalence of interactions drug-enteral nutrition (EN) in Intensive Care Units (ICU) of seven teaching hospitals in Brazil, and to analyze the clinical significance of them. Information on medications and EN administered with 24 hours and 120 hours of hospitalization were collected. For identification of drug-EN interaction was employed software Drug Reax®. It was investigated 1.124 records. Of these, 320 patients, with 24 hours of hospitalization, were on EN, and 20 (6.3%) had drug-EN interaction. Of the 504 patients with 120 hours of hospitalization, 39 (7.7%) had drug-EN interaction. The most frequent drug-EN interactions of clinical significance were phenytoin-EN, warfarin-EN and levothyroxine-EN. Drug-EN interactions may interfere with the quality and cost effectiveness of care in ICU, so it is essential that the health team has knowledge about them.
Estudio multicéntrico, transversal retrospectivo, que tuvo como objetivo determinar la prevalencia de interacciones drogasnutrición enteral (NE) en Unidades de Cuidados Intensivos (UCI) de siete hospitales de enseñanza en Brasil, y analizar el significado clínico de las mismas. Fueran colectadas informaciones en 24 horas y 120 horas de hospitalización en los registros médicos. Para identificar las interacciones fármaco-NE se utilizó el software de Drug Reax®. Fueran investigados 1.124 registros. De éstos, 320 pacientes, con 24 horas de hospitalización, se encontraban en la NE, 20 (6,3%) presentarán interacción. De los 504 pacientes, con 120 horas de hospitalización, 39 (7,7%) tuvieron la interacción. Las interacciones fármacos-NE más frecuentes fueron: fenitoína-NE, levotiroxina-NE, warfarina-NE. Las interacciones fármacos-NE pueden interferir con la calidad de los cuidados en la UCI, por lo que es esencial que el equipo de salud tenga conocimientos al respecto.
Estudo multicêntrico, transversal e retrospectivo, que objetivou determinar a prevalência de interações fármaco-nutrição enteral (NE) em Unidades de Terapia Intensiva (UTI) de sete hospitais de ensino do Brasil, e analisar a significância clínica das mesmas. Foram coletadas informações sobre medicamentos e NE administrados com 24 horas e 120 horas de internação. Para identificação das interações fármaco-NE empregou-se o software Drug Reax®. Foram investigados 1.124 prontuários. Destes, 320 pacientes, com 24 horas de internação, estavam em uso de NE, sendo que 20 (6,3%) apresentaram interação fármaco-NE. Dos 504 pacientes, com 120 horas de internação, 39 (7,7%) apresentaram interação fármaco-NE. As potenciais interações fármaco-NE mais frequentes foram: fenitoína-NE, levotiroxina-NE e varfarina-NE. As interações fármaco-NE podem interferir na qualidade e no custo da assistência prestada em UTI e, desta forma, é essencial que a equipe de saúde tenha conhecimento sobre as mesmas.
https://doi.org/10.5935/0034-7167.20140011
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