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Complex post-traumatic stress disorder (CPTSD), executive function and attachment posttraumatic post traumatic CPTSD, CPTSD , (CPTSD) (CPTSD
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Paula, Gleysse G. M. de

; Moreira, Jacqueline de Oliveira

; Santos, Antônio José

Revista Latinoamericana de Psicopatologia Fundamental

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2023, Volume 26 elocation e220529

Des études menées auprès d’enfants et d’adolescents révèlent que l’exposition à long terme à des événements indésirables et le manque de soutien émotionnel et psychosocial peuvent conduire à des conditions de traumatisme complexe (TSPT_C) fournissant des difficultés qui affectent la régulation émotionnelle, la cognition, plus spécifiquement la fonction exécutive, les relations interpersonnelles, les relations et la constitution de l’identité. Ainsi, le but de cet essai est de réfléchir sur les aspects du développement cognitif, émotionnel, et de l’attachement chez les enfants qui sont exposés à l’expérience de la violence. denfants d dadolescents adolescents lexposition l exposition TSPT_C TSPTC TSPT C (TSPT_C émotionnelle cognition exécutive interpersonnelles lidentité. lidentité identité. identité l’identité Ainsi cognitif lattachement attachement lexpérience expérience violence

Los estudios realizados con niños y adolescentes revelan que la exposición prolongada a eventos adversos y la falta de apoyo emocional y psicosocial puede conducir a condiciones de traumatización compleja (TEPT_C) proporcionando dificultades que afectan la regulación emocional, cognitiva, relaciones interpersonales y constitución de la identidad. El objetivo de este ensayo es reflexionar sobre aspectos del desarrollo cognitivo, más específicamente la función ejecutiva, emocional, y del apego en niños que están expuestos a la experiencia de violencia. TEPT_C TEPTC TEPT C (TEPT_C cognitiva identidad cognitivo ejecutiva violencia

Estudos realizados com crianças e adolescentes sugerem que a exposição prolongada a eventos adversos e à falta de apoio emocional e psicossocial podem levar a quadros traumatizantes complexos (TEPT_C), proporcionando dificuldades que afetam a regulação emocional, a cognição, as relações interpessoais e a constituição da identidade. O objetivo deste ensaio é refletir sobre as dimensões cognitivas, mais especificamente das funções executivas, os aspectos emocionais e de apego em crianças, que foram expostos à cenários e experiências de violência. TEPT_C, TEPTC TEPT_C , TEPT C (TEPT_C) cognição identidade cognitivas executivas violência (TEPT_C

Studies conducted with children and adolescents suggest that long-term exposure to adverse events and the lack of emotional and psychosocial support can lead to complex traumatizing conditions (C_PSPT), providing difficulties that affect emotional regulation, cognition, interpersonal relationships and the constitution of identity. The aim of this essay is to reflect on about the cognitive, more specifically executive function abilities, emotional, and attachment dimensions in children, who have been exposed to the experience of violence. longterm long term C_PSPT, CPSPT C_PSPT , C PSPT (C_PSPT) regulation cognition identity cognitive abilities violence (C_PSPT

https://doi.org/10.1590/1415-4714.e220529

A Low Cost, High-Reliability Receiver System for Reading Passive RFID Tags
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Oliveira, Nicollas R. de

; Boaventura, Lucas P.

; Ferreira, Tadeu N.

; Magri, Vanessa P. R.

; Pereira, Jacqueline S.

; Mattos, Diogo M. F.

Journal of Microwaves, Optoelectronics and Electromagnetic Applications

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dec 2021, Volume 20 N. 4 Pages 812 - 822

Abstract: En | Text: En | PDF: En

Abstract Radio-Frequency Identification (RFID) is one of the leading enabling technologies of the Internet of Things (IoT) at low cost and high granularity scenarios. The cost of implementing IoT applications concerns the development and operation of receiver systems for reading labels. In this paper, we propose a low-cost receiver system based on off-the-shelf components allied to the development of a microstrip antenna. The proposed system is capable of receiving and processing digital signals scattered back from a passive RFID tag. The proposal relies on a Python application embedded in Raspberry Pi hardware, in which a bank of digital filters processes the signal. The proposal separates the received signal into sub-bands and implements a decision-maker that detects and codes radiofrequency carriers’ presence in sub-bands. Simulation using artificial random noise proves that the proposed and implemented decision-maker achieves 92% reliability for a Signal-to-Noise ratio between 1.6 dB and 2.3 dB. The evaluation of the printed dipole antennas pair for the RFID receiver system indicates a return loss of 19.22 dB for operation at 915 MHz.

https://doi.org/10.1590/2179-10742021v20i4254757

Clinical characteristics and evolution of hematological patients and COVID-19 in Argentina: a report from the Argentine Society of Hematology
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Basquiera, Ana L.

; García, Mercedes J

; Martinez Rolón, Juliana

; Olmedo, Julieta

; Laviano, Julia

; Burgos, Rubén

; Caeiro, Gastón

; Remaggi, Guillermina

; Raña, Pablo

; Paoletti, Mariano

; González, Carlos M.

; Fernández, Isolda

; Pavlovsky, Astrid

; Perusini, Maria A.

; Rodriguez, Andrea

; Guanchiale, Luciana

; Carvani, Analia

; Mandrile, Laura

; Figueroa, Flavia

; Vicente Reparaz, Ángeles

; Fragapane Mathus, Patricia N.

; Garate, Gonzalo

; Fauque, María E.

; Kantor, Gustavo

; Cruset, Soledad

; Gonzalez Lorch, Jacqueline S.

; Szelagowski, Milagros

; Giarini, María P.

; Oliveira, Natalia

; García, María C.

; Ventriglia, María V.

; Pereyra, Patricio H.

; Gutierrez, Daniel R.

; Kusminsky, Gustavo

; Troccoli, Josefina

; Freitas, María J.

; Cranco, Santiago

; Del V.Sanchez, Natalia

; Rey, Irene

; Funes, María E.

; Jarchum, Sol

; Freue, Julian

; Miroli, Augusto

; Guerrero, Osvaldo

; López Ares, Lisa

; Campestri, Reinaldo

; Bove, Victor

; Salinas, Graciela N.

; Cabrejo, María

; Milone, Jorge H.

; Zabaljauregui, Soledad

; Gotta, Daniel

; Dupont, Juan Carlos

; Stemmelin, German

Medicina (Buenos Aires)

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aug 2021, Volume 81 N. 4 Pages 536 - 545

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Individuals with malignancies and COVID-19 have a lower survival compared with the general population. However, the information about the impact of COVID-19 on the whole hematological population is scarce. We aimed to describe the 30th day overall survival (OS) after COVID-19 infection in pa tients with a hematological disease in Argentina. A completely anonymous survey from the Argentine Society of Hematology was delivered to all the hematologists in Argentina; it started in April 2020. A cut-off to analyze the data was performed in December 2020 and, finally, 419 patients were reported and suitable for the analysis (average age: 58 years, 90% with malignant diseases). After the COVID-19 diagnosis, the 30-day OS for the whole population was 80.2%. From the entire group (419), 101 (24.1%) individuals required intensive care unit admission, where the 30-day OS was 46.6%. Among allogeneic stem cell transplant recipients, the 30-day OS was 70.3%. Factors associated with a low OS were two or more comorbidities, an active hematological disease and history of chemotherapy. In individuals with the three factors, the 30-day OS was 49.6% while the 30-day OS in those without those factors was 100%. Patients with hematological diseases have a higher mortality than the general population. This group represents a challenge and requires careful decision-making of the treatment in order not to compromise the chances of cure.

Resumen El presente estudio tuvo por objetivo primario conocer la mortalidad de pacientes con enfermedad hematológica que presentaron infección por COVID-19 en Argentina. Para ello se difundió una encuesta desde la Sociedad Argentina de Hematología (SAH) entre los hematológos para informar sobre los pacientes con enfermedades hematológicas y diagnóstico de infección por SARS- CoV-2, entre el 19/4/2020, y el 7/12/2020. Se incluyeron individuos de todas las edades con diagnóstico de enfermedad hematológica benigna o maligna e infección por SARS-CoV-2 confirmada por técnica de RT-PCR. Se analizaron 419 pacientes (mediana 58 años; 90% enfermedades malignas). La supervivencia al día 30 fue de 80.2%. La supervivencia fue menor en aquellos que requirieron internación (74.2%), cuidados intensivos (46.6%) y asistencia respiratoria mecánica (36.8%). Entre los trasplantados alogénicos la supervivencia fue 70.3%. Los factores vinculados a la supervivencia global fueron las comorbilidades, el estado de la enfermedad al momento de la infección y el antecedente de quimioterapia. Se pudo establecer un score en el que aquellos que tuvieron un puntaje de 4 alcanzaron una supervivencia del 49.6% al día 30, mientras que la de los pacientes con score 0 fue del 100% a 30 días. En comparación con la población general, los pacientes con enfermedades hematológicas presentan una mayor mortalidad vinculada al COVID-19, motivo por el cual es primordial definir pautas destinadas a disminuir la exposición de los mismos sin comprometer las posibilidades de beneficiarse del tratamiento de la enfermedad de base.

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Influence of creep feeder position on the behavior and performance of preweaning piglets and sows in a hot climate environment
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OLIVEIRA, EWERSON S.

; NASCIMENTO, ELAINE L.L.

; LIMA, HELLEN K.S.

; NEVES, JACQUELINE S.

; DAMASCENO, JAMILLY G.

; SILVA, JULIANA C.

; OLIVEIRA, NATÁLIA C.

; NASCIMENTO, PEDRO H.

; OLIVEIRA, RAFAEL A.

; ARAÚJO, VITOR O.

; VIEIRA, MARIA F.A.

; MONTEIRO, BRUNO M.

; SCHINCKEL, ALLAN P.

; GARBOSSA, CESAR A.P.

Anais da Academia Brasileira de Ciências

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2021, Volume 93 N. 3 elocation e20200248

Abstract: En | Text: En | PDF: En

Abstract The use of creep feeding for preweaning piglets is important to improve the performance of the piglets. The objective of this experiment was evaluate the effect of using or altering the position of piglet’s creep feeder during lactation on piglet’s performance and on behavior of piglets and sows kept in a hot climate environment. Forty-five sows and their litters at 10 days of lactation were randomly distributed into three treatments: front feeder (FF) - near the side of the sow’s head; back feeder (BF) - near the side of the rump of the sow; and no feeder (NF). All piglets were weighed individually to evaluate the average weight, weight gain and coefficient of variation of the weight. Behavior assessments of the piglets and sows were recorded in 3 period. At 15 and 21 d, piglets of the FF treatment were heavier (P ≤ 0.0001) than piglets of the other treatments. At 10-21d piglets of FF treatment had 76.2% less belly nosing behavior than the NF piglets (P=0.015). The treatments had no impact on behavior of the sows. The creep feeders positioned in the front of the farrowing crate increased piglet growth rate and decreased frequency of belly nosing behavior.

https://doi.org/10.1590/0001-3765202120200248 368 downloads

Facial Clinimetric Evaluation Scale and Synkinesis Assessment Questionnaire Translation into Brazilian Portuguese: A Validation Study
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Tavares-Brito, Joana

; Fonseca, Anna Carolina de Oliveira

; Torres, Rodolfo Prado

; Veen, Martinus M. van

; Greene, Jacqueline

; Salomone, Raquel

; Bahmad Jr, Fayez

; Hadlock, Tessa

; Bento, Ricardo Ferreira

International Archives of Otorhinolaryngology

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mar 2020, Volume 24 N. 1 Pages e24 - e30

Abstract: En | Text: En | PDF: En

Abstract Introduction Facial nerve palsy results in both functional disability and psychological morbidity. There are several well-established grading scales to quantify the quality of life of these patients. Objective Translate and validate the Facial Clinimetric Evaluation (FaCE) scale and Synkinesis Assessment Questionnaire (SAQ) to Brazilian Portuguese. Methods This study adopted a forward-backward translation method and performed cross-cultural adaptation. A pilot study was conducted to correct any confusing language and to evaluate content validity. A validation study was then performed. Internal consistency of the Brazilian Portuguese version of the FaCE and SAQ items was evaluated by Cronbach’s alpha coefﬁcient. Construct validity was assessed by Spear- man’s Rank Correlation Coefﬁcient between FaCE and SAQ scores to eFACE, House- Brackmann, Short Form 12 (SF-12) and Facial Disability Index (FDI) (sub)scores. Results A total of 90 patients were included. Cronbach’s alpha for total domain scored 0.881 for FaCE and 0.809 for SAQ. FaCE total score correlation to eFACE total and House- Brackmann showed Spearman’s r value of 0.537 and -0.538, respectively (p < 0.001). SAQ correlation to eFACE synkinesis subdomain was -0.449 (p < 0.001). No correlation was found between SAQ and HB score. FaCE total score correlations were of 0.301 and 0.547 for SF-12 PCS and MCS, respectively (p < 0.001). Correlation between FaCE total and FDI Physical and Social/well-being functions were 0.498 and 0.567 (p < 0.001). Conclusion Brazilian Portuguese FaCE scale and SAQ versions achieved high validity and reliability in the present study. These translated instruments demonstrated good psychometric properties, being proper to use in clinical practice in Brazil and with Brazilian Portuguese speakers.

https://doi.org/10.1055/s-0039-1697992 635 downloads

Criação e Implementação de um Banco de Dados Prospectivo e Multicêntrico de Pacientes com Infarto Agudo do Miocárdio: RIAM
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Vaz, Jacqueline

; Abelin, Anibal Pereira

; Schmidt, Marcia Moura

; Oliveira, Pedro Piccaro de

; Gottschall, Carlos A. M.

; Rodrigues, Clarissa Garcia

; Quadros, Alexandre Schaan de

Arquivos Brasileiros de Cardiologia

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mar 2020, Volume 114 N. 3 Pages 446 - 455

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Fundamento Registros multicêntricos representativos do mundo real podem fornecer informações importantes, mas existem poucos estudos descrevendo como implementar estas ferramentas. Objetivo Descrever o processo de implementação de um banco de dados em infarto agudo do miocárdio com supradesnivelamento do segmento ST (IAMCST) em um hospital de referência e sua aplicação para outros centros com uma plataforma online . Métodos Nossa instituição implementou em 2009 um Registro de Infarto Agudo do Miocárdio (RIAM), com a inclusão prospectiva e consecutiva de todos os pacientes com diagnóstico de IAMCST que internaram na instituição. No período de março de 2014 a abril de 2016 foi realizada a migração para o sistema online com o software REDCap e expansão do registro para outros centros. A plataforma REDCap é um software de uso gratuito disponibilizado pela Universidade Vanderbilt a instituições interessadas em pesquisa, mediante cadastramento prévio. Resultados Foram realizadas as seguintes etapas do aprimoramento e expansão do registro: 1. Padronização das variáveis; 2. Implementação do software REDCap ( Research Electronic Data Capture ) institucional; 3. Desenvolvimento de formulários de coleta de dados ( Case Report Form - CRF); 4. Expansão do registro para outros centros de referência utilizando o software REDCap; 5. Treinamento da equipe e dos centros participantes pelo POP (Procedimento Operacional Padrão). Conclusões A descrição da metodologia utilizada para implementar e expandir o RIAM pode auxiliar outros centros e pesquisadores a realizar estudos semelhantes, compartilhar informações entre instituições, o desenvolvimento de novas tecnologias em saúde e auxiliar nas políticas públicas em doenças cardiovasculares. (Arq Bras Cardiol. 2020; 114(3):446-455)

Abstract Background Multicenter registries representing the real world can be a significant source of information, but few studies exist describing the methodology to implement these tools. Objective To describe the process of implementing a database of ST-segment elevation acute myocardial infarction (STEMI) at a reference hospital, and the application of this process to other centers by means of an online platform. Methods In 2009, our institution implemented an Registry of Acute Myocardial Infarction (RIAM), with the prospective and consecutive inclusion of every patient admitted to the institution who received a diagnosis of STEMI. From March 2014 to April 2016, the registries were uploaded to a web-based system using the REDCap software and the registry was expanded to other centers. Upon subscription, the REDCap platform is a noncommercial software made available by Vanderbilt University to institutions interested in research. Results The following steps were taken to improve and expand the registry: 1. Standardization of variables; 2. Implementation of institutional REDCap (Research Electronic Data Capture); 3. Development of data collection forms (Case Report Form - CRF); 4. Expansion of registry to other reference centers using the REDCap software; 5. Training of teams and participating centers following an SOP (Standard Operating Procedure). Conclusion The description of the methodology used to implement and expand the RIAM may help other centers and researchers to conduct similar studies, share information between institutions, develop new health technologies, and assist public policies regarding cardiovascular diseases. (Arq Bras Cardiol. 2020; 114(3):446-455)

https://doi.org/10.36660/abc.20190036 2032 downloads

Preparation of Magnetoliposomes with a Green, Low-Cost, Fast and Scalable Methodology and Activity Study against S. aureus and C. freundii Bacterial Strains
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Silva, Rosangela M. F. da Costa e

; Lara, Luciano R. S.

; López, Jorge L.

; Andrade, Ângela L.

; Oliveira, Junnia A. C.

; Takahashi, Jacqueline A.

; Vieira, Henriete S.

; Matencio, Tulio

; Stumpf, Humberto O.

; Domingues, Rosana Z.

Journal of the Brazilian Chemical Society

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dec 2018, Volume 29 N. 12 Pages 2636 - 2645

Abstract: En | Text: En | PDF: En

A novel, fast, low-cost and scalable methodology to prepare stable magnetoliposomes (MGLs), without the use of organic solvents, is described. The concept of the work is based on the dual use of soy lecithin associated to a new liposome preparation methodology. Soy lecithin was used to coat the nanoparticles of magnetite (Fe3 O4 @lecithin) and for encapsulation of Fe3 O4 @lecithin (Lip-Fe3 O4 @lecithin). Liposomes with size less than 160 nm, polydispersity index of 0.25 and zeta potential of -41 mV, were prepared with the use of autoclave and sonication. The liposomal formulations containing magnetite and stigmasterol (Lip-Fe3 O4 @lecithin, Lip-Stigma and Lip-Stigma-Fe3 O4 @lecithin) were shown to be promising for the application as antibacterial. The liposomal formulation and magnetite were characterized by the following techniques: conventional and high-resolution transmission electron microscopy (TEM/HRTEM), energy-filtered transmission electron microscopy (EFTEM), proton nuclear magnetic resonance (1H NMR), Fourier transform infrared spectroscopy (FTIR), X-ray powder diffraction (XRPD), dynamic light scattering (DLS) and zeta potential. The Lip-Fe3 O4 @lecithin had a minimum inhibitory concentration (MIC) of 8.4 µg mL-1 in the presence of 200 Oe magnetic field against S. aureus.

https://doi.org/10.21577/0103-5053.20180144 733 downloads

Social anxiety symptoms and body image dissatisfaction in medical students: prevalence and correlates
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Regis, Jacqueline M. Oliveira

; Ramos-Cerqueira, Ana Teresa A.

; Lima, Maria Cristina P.

; Torres, Albina R.

Jornal Brasileiro de Psiquiatria

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jun 2018, Volume 67 N. 2 Pages 65 - 73

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo O transtorno de ansiedade social (TAS) e a insatisfação com a imagem corporal (IIC) são problemas comuns em estudantes universitários, mas poucos estudos avaliaram estudantes de Medicina. O objetivo do estudo foi estimar a prevalência, a gravidade e os correlatos de sintomas de TAS e IIC em estudantes de Medicina de uma universidade pública brasileira. Métodos Estudo transversal com 479 estudantes utilizando os seguintes instrumentos de avaliação estruturados: Social Phobia Inventory (SPIN), Body Shape Questionnaire (BSQ) e Beck Depression Inventory (BDI). Análises bivariadas foram seguidas de modelos de regressão logística para identificar preditores independentes de sintomas de TAS, IIC e ambos os desfechos combinados. Resultados A maioria dos estudantes era solteira (99%) e do sexo feminino (58,7%). As prevalências de sintomas de TAS (SPIN ≥ 19) e de ICC (BSQ ≥ 81) foram de 36,3% e 34,7%, respectivamente. Sintomas depressivos (BDI ≥ 19) ocorreram em 8,8% da amostra. Sintomas de TAS associaram-se de modo independente com: IIC, pensamentos de abandonar o curso, dificuldade de fazer amigos, sintomas depressivos e tratamento de saúde mental antes de ingressar na universidade. Além de sintomas de TAS, IIC associou-se com sexo feminino, dificuldade de fazer amigos, sintomas depressivos e índice de massa corporal (IMC). Setenta e oito estudantes (16,3%) apresentaram sintomas de TAS e IIC, o que se associou com sexo feminino, dificuldade de fazer amigos, insatisfação com o curso, sintomas depressivos e IMC. Conclusão Sintomas de TAS e IIC são problemas comuns e inter-relacionados que devem ser rastreados em estudantes de Medicina. A identificação de correlatos específicos pode contribuir para a elaboração de medidas preventivas minimizando o sofrimento e o impacto negativo desses problemas de saúde mental nos relacionamentos e no desempenho acadêmico desses estudantes.

ABSTRACT Objective Social anxiety disorder (SAD) and body image dissatisfaction (BID) are common problems among college students, but few studies focused on medical students. We aimed to estimate the prevalence, severity and correlates of SAD symptoms and BID among medical students of a Brazilian public university. Methods A cross-sectional study with 479 students, using structured instruments: Social Phobia Inventory (SPIN), Body Shape Questionnaire (BSQ), and Beck Depression Inventory (BDI). Bivariate analyses were followed by logistic regression models to obtain independent predictors of SAD symptoms, BID and both outcomes combined. Results Most students were single (99%) and female (58.7%). The prevalence rates of SAD symptoms (SPIN ≥ 19) and BID (BSQ ≥ 81) were 36.3% and 34.7%, respectively. Depressive symptoms (BDI ≥ 19) occurred in 8.8% of the sample. SAD symptoms were independently associated with: BID, thoughts of abandoning the course, difficulty making friends, depressive symptoms, and mental health treatment prior to university. Besides SAD symptoms, BID was associated with female sex, difficulty making friends, depressive symptoms, and body mass index (BMI). Seventy-eight students (16.3%) presented SAD symptoms and BID, which was associated with female sex, difficulty making friends, dissatisfaction with the course, depressive symptoms and BMI. Conclusion SAD symptoms and BID are common and related problems that should be screened for among medical students. The identification of specific correlates could contribute to the elaboration of preventive measures, minimizing the distress and negative impact of these mental health problems on relationships and academic performance.

https://doi.org/10.1590/0047-2085000000187 5108 downloads

Bacterial resistance in bats from the Phyllostomidae family and its relationship with unique health
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Sens-Junior, Helio

; Trindade, Wesley A.

; Oliveira, Aliny F.

; Zaniolo, Melissa M.

; Serenini, Grazielli F.

; Araujo-Ceranto, Jacqueline B.

; Gonçalves, Daniela D.

; Germano, Ricardo M.

Pesquisa Veterinária Brasileira

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jun 2018, Volume 38 N. 6 Pages 1207 - 1216

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: A família Phyllostomidae se destaca entre as famílias de morcegos encontrados no Brasil, com diversificadas espécies e hábitos alimentares, sendo a única a apresentar representantes frugívoros, podendo ser encontrada tanto em meio urbano, como de vida livre, em busca de melhores condições reprodutivas e alimentares. Essa versatilidade de ambientes pode estar associada à incidência e/ou distribuição de determinadas doenças por agentes patogênicos. O presente trabalho objetivou identificar a microbiota oral e perianal e detectar a resistência bacteriana em morcegos frugívoros capturados próximos às comunidades habitadas pelo homem na região noroeste do estado do Paraná. Foram capturados 68 morcegos, de quatro espécies da família Phyllostomidae, são eles Artibeus lituratus, Artibeus planirostris, Carollia perspicillata e Sturnira lillium, oriundos de fragmentos de Mata da microrregião de Umuarama, estado do Paraná. Um total de 64 isolados de bactérias da região oral e 39 da região perianal foram submetidos, identificação e posteriormente teste de susceptibilidade a 22 antimicrobianos de uso humano e veterinário. As bactérias mais prevalentes foram Escherichia coli 33,3% na região da boca e 35,90% na região perianal, Enterobacter aerogenes 12,7% e 5,13%, Enterobacter agglomerans 7,9% e 10,25% e Serratia liquefaciens 9,5% e 5,13% na região da boca e perianal, respectivamente. Todas as espécies de morcegos estudadas apresentaram cepas que foram resistentes, e algumas multirresistência aos antimicrobianos. A espécie que apresentou maior índice de multirresistência aos antimicrobianos foi Carollia perspicillata, com três cepas na região oral resistente a 15 antimicrobianos, e duas na perianal, com resistência a 13 e 10 antimicrobianos respectivamente. Baseados nos resultados encontrados, é possível concluir que a microbiota oral e perianal de morcegos, é composta por diversas espécies de enterobactérias, resistentes a um, ou vários antimicrobianos utilizados na medicina humana e veterinária, tornando-se um problema, e um alerta futuro para a saúde única, uma vez que foram encontrados elevados percentuais de resistência contra antimicrobianos utilizados em larga escala tais como ampicilina, amoxicilina e amoxicilina+clavulonato.

ABSTRACT: The Phyllostomidae family is important among the bats found in Brazil, with several species and diverse eating habits, and is the only one to have frugivorous representatives. These bats can be found in urban and in wild life environments in search for the best reproductive and feeding conditions. The versatility of environments can be associated with the incidence and/or distribution of some diseases through pathogenic agents. The present paper has the purpose to identify the oral and perianal microbiota and to detect the bacterial resistance of frugivorous bats captured near communities inhabited by humans in the northwestern region of the state of Paraná. A total of 68 bats were captured, belonging to four species of the Phyllostomidae family, namely Artibeus lituratus, Artibeus planirostris, Carollia perspicillata and Sturnira lillium, originated from forest fragments in the micro region of Umuarama, state of Paraná. A total of 64 isolates from oral bacteria and 39 from perianal region were submitted to identification. They were later submitted to a susceptibility test to 22 human and veterinary antimicrobials. The most prevalent bacteria were Escherichia coli 33.3% in the oral region, and 35.90% in the perianal region, Enterobacter aerogenes 12.7% and 5.13%, Enterobacter agglomerans 7.9% and 10.25%, and Serratia liquefaciens 9.5% and 5.13% in the oral and perianal region respectively. All bat species studied had resistant strains, with a few of them presenting multi-resistance to antimicrobials. The species with the highest multi-resistance index to antimicrobials was Carollia perspicillata, with three strains of the oral region resistant to 15 antimicrobials; it also presented two strains in the perianal region, which were resistant to 13 and 10 antimicrobials respectively. Based on the results found, it is possible to conclude that the oral and perianal microbiota of bats is composed of several enterobacterial species resistant to one or several antimicrobials used in human and veterinarian medicine. This is an issue and a future warning for unique health, since high percentages of resistance were found against antimicrobials broadly used, such as ampicillin, amoxicillin and amoxicillin+clavulonate.

https://doi.org/10.1590/1678-5150-pvb-5185 1095 downloads

10.

Mood disorder, anxiety, and suicide risk among subjects with alcohol abuse and/or dependence: a population-based study
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Wiener, Carolina D.

; Moreira, Fernanda P.

; Zago, Alethea

; Souza, Luciano M.

; Branco, Jeronimo C.

; Oliveira, Jacqueline F. de

; Silva, Ricardo A. da

; Portela, Luis V.

; Lara, Diogo R.

; Jansen, Karen

; Oses, Jean P.

Brazilian Journal of Psychiatry

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jan 2018, Volume 40 N. 1 Pages 1 - 5

Abstract: En | Text: En | PDF: En

Objective: To evaluate the prevalence of alcohol abuse and/or dependence in a population-based sample of young adults and assess the prevalence of comorbid mood disorders, anxiety, and suicide risk in this population. Methods: This cross-sectional, population-based study enrolled 1,953 young adults aged 18-35 years. The CAGE questionnaire was used to screen for alcohol abuse and/or dependence, with CAGE scores ≥ 2 considered positive. Psychiatric disorders were investigated through the structured Mini International Neuropsychiatric Interview (MINI). Results: Alcohol abuse and/or dependence was identified in 187 (9.60%) individuals (5.10% among women and 15.20% among men). Alcohol abuse and/or dependence were more prevalent among men than women, as well as among those who used tobacco, illicit drugs or presented with anxiety disorder, mood disorder, and suicide risk. Conclusion: These findings suggest that alcohol abuse and/or dependence are consistently associated with a higher prevalence of psychiatric comorbidities, could be considered important predictors of other psychiatric disorders, and deserve greater public heath attention, pointing to the need for alcohol abuse prevention programs.

https://doi.org/10.1590/1516-4446-2016-2170 3167 downloads

11.

Maytenus distichophylla and Salacia crassifolia: source of products with potential acetylcholinesterase inhibition
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Ferreira, Fernanda L.

; Rodrigues, Vanessa G.

; Silva, Fernando C.

; Matildes, Bibiane L.G.

; Takahashi, Jacqueline A.

; Silva, Gracia D.F.

; Duarte, Lucienir P.

; Oliveira, Djalma M.

; Filho, Sidney A.V.

Revista Brasileira de Farmacognosia

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aug 2017, Volume 27 N. 4 Pages 471 - 474

Abstract: En | Text: En | PDF: En

ABSTRACT The phytochemical study of the extract leaves from Maytenus distichophylla Mart. and Salacia crassifolia (Mart. ex Schult.) G. Don, Celastraceae, resulted in the isolation of 3-oxofriedelane, 3β-hydroxyfriedelane, 3β,24-dihydroxyfriedelane, 3-oxo-28,29-dihydroxyfriedelane, two mixtures of pentacyclic triterpenes (α-amyrin with β-amyrin and 3β-stearyloxy-urs-12-ene with 3β-stearyloxy-olean-12-ene), 3β-palmityloxy-urs-12-ene, the steroid β-sitosterol and its glycosylated derivative β-glucosyl-β-sitosterol, tritriacontanoic acid and the natural polymer gutta percha. The chemical structures of these constituents were established by IR, 1H and 13C NMR spectral data. Crude extracts, the mixtures of triterpenes and the isolated constituents were subjected to in vitro acetylcholinesterase inhibitory evaluation. Acetylcholinesterase inhibitory effect was observed for crude chloroform extract leaves from M. distichophylla (100%) and S. crassifolia (97.93 ± 5.63%) and for the triterpenes 3β,24-dihydroxyfriedelane (99.05 ± 1.12%), 3-oxo-28,29-dihydroxyfriedelane (90.59 ± 3.76%) and 3β-palmityloxy-urs-12-ene (97.93 ± 1.47%). The percent inhibitions induced by these natural products were very similar to those produced by physostigmine (93.94 ± 2.10%) a standard acetylcholinesterase inhibitor. Therefore, these results open perspectives for the use of these species as source of compounds with similar physostigmine pharmacological effect.

https://doi.org/10.1016/j.bjp.2016.12.006 447 downloads

12.

Equine infectious anaemia in equids of Southern Pantanal, Brazil: seroprevalence and evaluation of the adoption of a control programme
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Nogueira, Márcia F.

; Oliveira, Jacqueline M.

; Santos, Carlos J.S.

; Petzold, Hildeberto V.

; Aguiar, Daniel M.

; Juliano, Raquel S.

; Reis, Jenner K.P.

; Abreu, Urbano G.P.

Pesquisa Veterinária Brasileira

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mar 2017, Volume 37 N. 3 Pages 227 - 233

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: A população de equídeos de serviço em Corumbá, Pantanal Sul, é muito numerosa e tem um papel crucial na principal atividade econômica do estado de Mato Grosso do Sul, a pecuária de corte extensiva. O objetivo deste trabalho foi estimar a prevalência atual da anemia infecciosa equina (AIE) em equídeos de serviço em fazendas do município de Corumbá, pelo teste oficial de imunodifusão em gel de ágar (IDGA), e avaliar a adoção do Programa de Prevenção e Controle da Anemia Infecciosa Equina proposto pela Embrapa Pantanal e entidades oficiais nos anos 1990. De setembro a novembro de 2009, quarenta fazendas distribuídas na área do município foram visitadas, e amostras de soro obtidas de 721 equinos e 232 muares. De acordo com publicações anteriores e os dados obtidos neste trabalho, concluiu-se que a prevalência da AIE nesta população aumentou de 18.17% para 38,60%, o que representa atualmente cerca de 13.000 animais infectados. Não houve diferença significativa entre as prevalências aparentes de equinos e muares. Verificou-se, também, que o programa de controle era desconhecido pela maior parte dos produtores, gerentes e capatazes entrevistados e, na percepção dos mesmos, a AIE não é uma ameaça importante a ser enfrentada. Dentre as variáveis estudadas, a prática da realização de testes sorológicos reduziu significantemente o risco para a presença de soropositividade para AIE, assim como a separação dos equipamentos de montaria e a segregação dos soropositivos.

ABSTRACT: The working equid population in Corumbá, Southern Pantanal, is very large and has a crucial role in the main economic activity of the State of Mato Grosso do Sul, the beef cattle industry. The aim of the present study was to estimate the prevalence of equine infectious anaemia (EIA) in working equids of ranches in the municipality of Corumbá, by the official agar gel immunodiffusion (AGID) test, and evaluate the adoption of the Programme for the Prevention and Control of Equine Infectious Anaemia proposed by Embrapa Pantanal and official entities in the 1990s. From September to November 2009, forty ranches distributed through the area of the municipality were visited, and serum samples were obtained from 721 equines and 232 mules. According to previous publications and the present data, it was concluded that the prevalence of EIA in this population has increased from 18.17% to 38.60%, which represents at this time approximately 13,000 infected animals. There was no significant difference between the apparent prevalence of equines and mules. It was also verified that the control programme was not known by the greater part of the interviewed ranch owners, managers and foremen and, in their perception, EIA is not a primary threat to address. Among the studied variables, the serologic testing practice significantly reduced the risk for the presence of EIA seropositivity, as well as the separation of riding equipment and segregation of seropositives.

https://doi.org/10.1590/s0100-736x2017000300005 1563 downloads

13.

Myxozoan infection in the muscle layer of the intestine of Rhamdia quelen from the Amazon River Basin, Brazil
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Abrunhosa, Jacqueline Pompeu

; Silva, Michele Velasco Oliveira da

; Sindeaux Neto, José Ledamir

; Santos, Patrícia de Fátima Sacco dos

; Matos, Patrícia Santos

; Sanches, Osimar de Carvalho

; Matos, Edilson Rodrigues

Ciência Rural

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nov 2016, Volume 46 N. 11 Pages 2024 - 2028

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: O presente estudo investigou a morfologia e patologia associada com a ocorrência de cistos de Myxobolus sp. no intestino do peixe siluriforme Rhamdia quelen . Comparações com outras espécies de Myxobolus que têm infectado intestinos de carpas e bagres de água doce demonstraram que os esporos piriformes de Myxobolus sp. são similares no formato dos anteriormente descritos para M. miyairii, M. duodenalis e M. cunhai , diferindo, no entanto, quanto ao tamanho. As análises morfométricas revelaram que os esporos maduros de Myxobolus sp. (10,9 x 5,1μm) são menores do que os da maioria das espécies, exceto para M. cunhai (10,0 x 5,0μm), que foi descrito infectando o bagre brasileiro Clarias pimelodus , embora os esporos sejam diferentes morfologicamente em relação à forma das cápsulas polares. Futuras pesquisas são necessárias para esclarecer as relações taxonômicas e filogenéticas entre espécies congêneres.

ABSTRACT: The present study investigated the morphology and pathology associated with the occurrence of cysts caused by Myxobolus sp. in the intestine of the silver catfish Rhamdia quelen . Comparisons with the other Myxobolus species that infect the intestines of cyprinids and siluriforms revealed that the pyriform spores of Myxobolus sp. are similar in shape to those described previously in M. miyairii, M. duodenalis and M. cunhai, but different in size. Morphometric analyses revealed that mature spores of Myxobolus sp. (10.9 x 5.1μm) are smaller than those of most species except M. cunhai (10.0 x 5.0μm), which has been described infecting the Brazilian catfish Pimelodus clarias , although the spores differ morphologically in relation to the shape of the polar capsules. Further research is necessary in order to clarify the taxonomic and phylogenetic relationships among these congeneric species.

https://doi.org/10.1590/0103-8478cr20151652 1059 downloads

14.

Abdominal perimeter is associated with food intake, sociodemographic and behavioral factors among adults in Southern Brazil: a population-based study
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Zarbato Longo, Giana

; Segheto, Wellington

; Silva, Danielle Cristina Guimarães da

; Queiroz Ribeiro, Andreia

; Silva Franco, Fernanda

; Danesio de Souza, Jacqueline

; Araujo Coelho, France

; Oliveira, Julicristie M.

Nutrición Hospitalaria

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feb 2015, Volume 31 N. 2 Pages 621 - 628

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Objective: The aim of this study is to investigate the abdominal perimeter determinants in adults who live in the city of Lages, SC. Design: A population-based cross-sectional study in adults from 20 to 59 years-old of the urban area (n=2.022). The dependent variable is the abdominal perimeter, the independent variables are: age, skin color self-reported, marital status, number of children, per capita income, education, physical activity, smoking, nutrition, self-reported diabetes mellitus, high blood pressure, body weight index. The differences between the mean perimeters were tested using ANOVA test and multiple linear regression for confounding adjustment. Results: The response rate was 98.2%, 52.3% were women. The mean abdominal perimeter for men was 93.66 cm (SD 13.8) and for women 92.80 cm (SD 14.5). There was a positive association of abdominal circumference with age (p<0.001) and negative regarding education. The abdominal perimeter means were higher for those insufficiently active (p<0.001), for former smokers (p<0.001), for those who consumed meat without fat removal (p = 0.001), for those who consumed fruit less than 5 times a week (p<0.001) and for those who were overweight (p<0.001). Remained positively associated with changes in abdominal obesity, insufficient physical activity, smoking, former smoker and consumption of meat without fat removal. All proximal variables remained positively associated with abdominal perimeter. Conclusions: The results have confirmed that diet, lifestyle and sociodemographic conditions determine a different distribution in abdominal fat, it is needed actions to promote a healthy lifestyle.

Objetivo: El objetivo de este estudio fue investigar los determinantes del perímetro abdominal en adultos que viven en la ciudad de Lages, SC. Diseño: Estudio transversal de base poblacional en adultos 20-59 años de edad, de la zona urbana (n= 2022). La variable dependiente fue el perímetro abdominal y las variables independientes fueron: edad, color de la piel auto dicho, estado civil, número de hijos, renta per cápita, nivel educacional, actividad física, tabaquismo, nutrición, diabetes mellitus auto dicho, presión arterial alta e índice de masa corporal. Las diferencias entre los promedios de perímetros se probaron a través de la ANOVA y de la regresión lineal múltiple, ajustada para los factores de confusión. Resultados: La tasa de respuesta fue de un 98,2%, de los cuales un 52,3% eran mujeres. El perímetro abdominal promedio para los hombres fue 93,66 cm (SD= 13,8 cm) y para las mujeres 92,80 cm (SD= 14,5). Hubo asociación positiva entre la circunferencia abdominal y la edad (p<0,001) y negativa entre la circunferencia abdominal y el nivel educacional. El promedio de perímetro abdominal fue más grande en personas insuficientemente activas (p<0,001), en los ex fumadores (p<0,001), en los que consumen carne sin la eliminación de grasa (p=0,001), en aquellos que consumían frutos menos de 5 veces a la semana (p<0,001) y en los que tenían sobrepeso (p<0,001). Se mantuvo una asociación positiva con los cambios en la obesidad abdominal, la insuficiente actividad física, el tabaquismo, ex fumador y el consumo de carne sin la eliminación de grasa. Todas las variables proximales se mantuvieron asociadas positivamente con el perímetro abdominal. Conclusiones: Los resultados confirman que la dieta, el estilo de vida y las condiciones sociodemográficas determinan una distribución diferente de la grasa abdominal, siendo necesarias acciones para promover un estilo de vida saludable.

https://doi.org/10.3305/nh.2015.31.2.8152 303 downloads

15.

In vitro EVALUATION OF THE ANTIBACTERIAL AND MODULATORY ACTIVITIES OF CORN AND SOY FIXED OILS
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TAVARES, Emanuele N

; ANDRADE, Jacqueline C

; De M. OLIVEIRA, Cícera Datiane

; TINTINO, Saulo R

; LIMA, Micheline A

; COUTINHO, Henrique D.M

Acta Biológica Colombiana

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jan 2015, Volume 20 N. 1 Pages 27 - 30

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Hoy en día, es ampliamente conocido que las cepas patógenas resistentes a antibioticos se están convirtiendo en uno de los mayores problemas de salud en el campo de la ciencias de la salud. También se sabe que los ácidos grasos pueden presentar actividad antimicrobiana. Los aceites de maíz y de soja son ricos en ácidos grasos. En este sentido, esta investigacion dirigida para evaluar la actividad antibacteriana y modulador de estos dos aceites fijos usados industrialmente. Ambas pruebas se realizaron utilizando el método de microdilución de concentración inhibitoria mínima en 1,024 mg/ml. La actividad de los aminoglucósidos se mejoró mediante la combinación de aceite de maíz usando E. coli 27. Uno de los mecanismos que podrían explicar la sinergia hacia el aceite de maíz, en parte, podría ser debido a la naturaleza hidrofóbica de los lípidos saturados e insaturados presentes en la muestra. Los resultados indican que los aceites fijos podrían desempeñar un papel como una forma alternativa para potenciar de los fármacos antimicrobianos.

Nowadays, it is widely known that resistant pathogenic strains are becoming one of the greatest health problems related to human sciences. It is also known that fatty acids can present antimicrobial activity. The corn and soy oils are rich in fatty acids. In this regard, this work aimed to evaluate antibacterial and modulatory activity of these two industrial fixed oils. Both tests were performed using the microdilution method to Minimum inhibitory concentration under 1024 mg/ml. The aminoglycosides activity was enhanced by combining corn oil using E. coli 27. One of the mechanisms that might explain the synergism toward the corn oil, in part, might be due to the hidrophobic nature of the saturated and unsaturated lipids present in the sample. The results indicate that fixed oils might play a role as an alternative way to potentiate of the antimicrobial drugs.

https://doi.org/10.15446/abc.v20n1.40764 1340 downloads

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