ABSTRACT There is great interest in varieties with greater competitive ability against weeds. This can be facilitated by path analysis, which involves the statistical evaluation and interpretation of the relationship between yield and its components. In this analysis, the occurrence of multicollinearity results in inconsistent estimates of the coefficients, and overestimates of the direct effects of the explanatory variables on the response variable. The aim of this study was to identify the characteristics with the greatest direct effect on pod yield and green and dry bean yields in traditional cowpea varieties, evaluated in competition with weeds in two experiments. In addition, the presence of multicollinearity was investigated in the analyses. In Experiment-1, twelve varieties with the highest bean yields in a preliminary evaluation were assessed in a randomized block design with five replications. In Experiment-2, six varieties, selected in the preliminary evaluation, were assessed using two methods of weed management: three of the most productive and three of the least productive. Randomized blocks and split plots were used, with five replications. Multicollinearity, indicated by the number of conditions and the variance inflation values, was greater in Experiment-2. In the six cases under study (three yields x two experiments), the number of pods per plant had the greatest direct effect on yield. analysis components coefficients variable experiments addition analyses Experiment1, Experiment1 Experiment 1, 1 Experiment-1 replications Experiment2, Experiment2 2, 2 Experiment-2 management used Multicollinearity values Experiment2. 2. experiments, , experiments) Experiment-

RESUMO Objetivo: Resumir as principais descobertas dos RNA não codificantes (ncRNAs) na síndrome de Turner (ST), correlacionando essas biomoléculas com as manifestações clínicas observadas nos pacientes afetados. Fontes de dados: Foram realizadas pesquisas nas bases de dados da Biblioteca Nacional de Medicina dos Estados Unidos (PubMed), Biblioteca Científica Eletrônica Online (SciELO) e ScienceDirect, abrangendo artigos originais em inglês publicados de 2014 a 2023. Os descritores utilizados foram: "lncRNAs e síndrome de Turner", "miRNAs e síndrome de Turner" e "circRNAs e síndrome de Turner". Os estudos incluídos abordaram o papel dos ncRNA nas características clínicas dos pacientes com ST. Os critérios de exclusão compreenderam textos de resumos, relatórios, resenhas e monografias. Síntese dos dados: Identificamos 147 estudos, dos quais sete foram incluídos no estudo. Na análise dos microRNAs, o miR-486-5p e o miR-320a se destacaram, estando associados ao desenvolvimento ovariano; o miR-126-3p e o miR-126-5p foram relacionados a uma maior rigidez aórtica. Com relação aos RNAs, a regulação negativa do XIST indicou disfunções na inativação do cromossomo X. Quanto aos circRNA, circPPP2R3B, circCSF2RA e circPCTN foram associados a funções imunológicas, enquanto circ_0090421, circ_0090392 e circ_0089945 foram vinculados ao desenvolvimento cardíaco. Conclusões: Os dados desses estudos demonstram que essas biomoléculas desempenham papéis cruciais em processos relacionados a características específicas observadas em pacientes com ST. Além de serem sugeridos como biomarcadores potenciais, os quais podem ser úteis na prática clínica. Objetivo ncRNAs (ncRNAs ST, ST , (ST) afetados PubMed, PubMed (PubMed) SciELO (SciELO ScienceDirect 201 2023 lncRNAs Turner, miRNAs circRNAs Turner. . resumos relatórios monografias 14 estudo microRNAs miR4865p miRp miR 486 5p p miR320a miRa 320a destacaram ovariano miR1263p 126 3p miR1265p aórtica RNAs X circRNA circPPP2R3B circPPPRB circPPP R B circCSFRA circCSF RA imunológicas circ0090421 circ 0090421 circ_0090421 circ0090392 0090392 circ_009039 circ0089945 0089945 circ_008994 cardíaco Conclusões potenciais clínica (ST (PubMed 20 202 1 48 12 circ009042 009042 circ_009042 circ009039 009039 circ_00903 circ008994 008994 circ_00899 2 4 circ00904 00904 circ_00904 circ00903 00903 circ_0090 circ00899 00899 circ_0089 circ0090 0090 circ_009 circ0089 0089 circ_008 circ009 009 circ_00 circ008 008 circ00 00 circ_0 circ0 0 circ_

ABSTRACT Objective: The aim of this study was to summarize the main findings of non-coding RNA (ncRNAs) in Turner syndrome (TS), correlating these biomolecules with the clinical manifestations in affected patients. Data source: Searches were conducted in the databases of the United States National Library of Medicine (PubMed), Scientific Electronic Library Online (SciELO), and ScienceDirect, covering original English articles published from 2014 to 2023. Descriptors used included "lncRNAs and Turner Syndrome," "miRNAs and Turner Syndrome," and "circRNAs and Turner Syndrome." The studies that were included addressed the role of ncRNAs in the clinical characteristics of patients with TS. Exclusion criteria comprised texts in abstracts, reports, reviews, and monographs. Data synthesis: We identified 147 studies, of which seven were included. In the analysis of microRNAs, miR-486-5p and miR-320a stood out, being associated with ovarian development; miR-126-3p and miR-126-5p were related to greater aortic stiffness. Regarding long non-coding RNAs, the downregulation of XIST indicated dysfunctions in X chromosome inactivation. Concerning circular RNAs, circPPP2R3B, circCSF2RA, and circPCTN were related to immunological functions, while circ_0090421, circ_0090392, and circ_0089945 were linked to cardiac development. Conclusions: The data from these studies demonstrate that these biomolecules play crucial roles in processes related to specific characteristics observed in TS patients. Besides being suggested as potential biomarkers, they may be useful in clinical practice. Objective noncoding non coding (ncRNAs TS, , (TS) source PubMed, PubMed (PubMed) SciELO, SciELO (SciELO) ScienceDirect 201 2023 lncRNAs Syndrome, Syndrome miRNAs circRNAs Syndrome. abstracts reports reviews monographs synthesis 14 microRNAs miR4865p miRp miR 486 5p p miR320a miRa 320a a out development miR1263p 126 3p miR1265p stiffness RNAs inactivation circPPP2R3B circPPPRB circPPP R B circCSF2RA circCSFRA circCSF RA functions circ0090421 circ 0090421 circ_0090421 circ0090392 0090392 circ_0090392 circ0089945 0089945 circ_008994 Conclusions biomarkers practice (TS (PubMed (SciELO 20 202 1 48 12 circ009042 009042 circ_009042 circ009039 009039 circ_009039 circ008994 008994 circ_00899 2 4 circ00904 00904 circ_00904 circ00903 00903 circ_00903 circ00899 00899 circ_0089 circ0090 0090 circ_0090 circ0089 0089 circ_008 circ009 009 circ_009 circ008 008 circ_00 circ00 00 circ_0 circ0 0 circ_

Resumo Atécnica de vergamento da madeira por vaporização se apresenta como opção viável para projetos de estruturas curvilíneas, como as gridshells. Madeiras coníferas são comumente adotadas em estruturas de cobertura, pois além da desejada relação entre resistência mecânica e densidade, permitem o completo tratamento da seção transversal da peça. Entretanto, características como a predominância de alburno ou de cerne e a presença de defeitos são variáveis que afetam o desempenho estrutural. O objetivo deste estudo foi avaliar o limite de vergamento de lamelas de Acrocarpus flaxinifloius (cedro indiano) com raio de curvatura de 21 cm em diferentes espessuras. Também se investigou o impacto da predominância de alburno ou cerne e da presença de defeitos na força de vergamento. A literatura indica que a flexibilização plástica por vapor ocorre a 100°C, com 2,4 minutos para cada milímetro de espessura da lamela, parâmetros estes considerados neste estudo. A análise estatística indicou o limite de 8 mm de espessura para o vergamento das lamelas e a maior presença de alburno ou de cerne, bem como os defeitos da madeira, não afetou significativamente a força de vergamento. curvilíneas gridshells cobertura densidade peça Entretanto estrutural cedro indiano 2 espessuras 100C C 100 100°C 24 4 2, lamela 10 1

Abstract The technique of bending wood by vaporization presents itself as a viable option for curvilinear structural projects, such as gridshells. Coniferous woods are often used in roof structures because, in addition to the desired relationship between mechanical strength and density, they allow the complete treatment of the cross-section of the piece. However, characteristics such as the predominance of sapwood or heartwood and the presence of defects are variables that affect structural performance. The aim of this study was to evaluate the bending limit of Acrocarpus laxinifloius (Indian cedar) veneers with a bending radius of 21 cm at different thicknesses. The impact of the predominance of sapwood or heartwood and the presence of defects on the bending strength was also investigated. The literature indicates that plastic flexibilization by steam occurs at 100°C, with 2.4 minutes for each millimeter of lamella thickness, which were the parameters considered in this study. The statistical analysis indicated a thickness limit of 8 mm for the lamellae to bend and the greater presence of sapwood or heartwood, as well as wood defects, did not significantly affect the bending force. projects gridshells because density crosssection cross section piece However performance Indian cedar 2 thicknesses investigated 100C C 100 100°C 24 4 2. force 10 1

RESUMO O artigo sustenta que a constituição brasileira outorgada em 1824 é uma complexa solução de compromisso com os debates e o projeto da Assembleia Constituinte dissolvida em 1823. Partindo desse pressuposto, busca destrinchar a intricada trama de ruptura e continuidade no longo trabalho de elaboração constitucional que vai da abertura da Assembleia Constituinte em 3 de maio de 1823 à outorga da Constituição, em 25 de março do ano seguinte. 182 pressuposto Constituição 2 seguinte 18 1

ABSTRACT The article argues that the Brazilian constitution granted in 1824 would be a complex compromise solution between the debates of the period and the Constituent Assembly project, which was dissolved in 1823. Starting from this assumption, the authors seek to unravel the intricate web between rupture and continuity in the long process of constitutional elaboration that extends from the opening of the Constituent Assembly on May 3, 1823, to the granting of the Constitution on March 25 of the following year. 182 project 1823 assumption 3 2 year 18 1

Abstract A continuous increase in levels of atmospheric pollution and emission restrictions has forced scientists and engineers to adopt new strategies to improve and develop internal combustion engines. One strategy is based on the development of new simulation methodologies using computational fluid dynamic (CFD) techniques, proposed in the present article. In this study,the dynamic loop methodology with ANSYS Fluent code is proposed to perform the numerical simulation ofa four-stroke spark ignition engine. The complexity of the real case was first simplified with three-dimensional CAD geometry, which was then discretized in ANSYS Meshing, whereby a hybrid mesh was created using prismatic and tetrahedral elements. Simulations for in-cylinder analyses were performed in cold flow and employing common flow parameters, such as swirl and tumble. The mesh quality results were classified as good or excellent, being higher than 0.79 for orthogonal quality criteria and lower than 0.36 for skewness criteria. Turbulent effects were introduced concerning the opening and closing of the valves. It was found that the turbulence increases during the intake stroke up to 90°, and during the power stroke, wherein the of the piston bowl, had a great contributionthat can be seen from the swirl and tumble profile for the engine cycle. In the case of the turbulence intensity, a sharp increase was registered during the admission step up to 90°, at which point the turbulence intensity was 4.0. It canbe concluded that this is an innovative approach, capable of simulating the engine motion profile in cold flow. engines CFD (CFD techniques article studythe study fourstroke four threedimensional three dimensional geometry Meshing elements incylinder cylinder parameters excellent 079 0 79 0.7 036 36 0.3 valves 90 90° bowl cycle 40 4 4.0 approach 07 7 0. 03 3 9 4.

Abstract: The proper choice of raw materials and manufacturing parameters for Cross Laminated Timber is essential to promote the proper bonding of the lamellas, aiming at their application in construction. However, few Brazilian species are currently used in the production of Cross Laminated Timber. The aim of this work was to characterize the bonding quality of four Brazilian reforestation species (Pinus elliottii (pino ellioti), Eucalyptus grandis (eucalipto), Toona ciliata (toona) and Acrocarpus fraxinifolius (lazcar)) in the manufacture of Cross Laminated Timber with two-component polyurethane adhesive and five different pressure levels (from 0,1 MPa to 1,3 MPa). Bonding quality was evaluated through delamination and glue line shear tests based on the European standard. Delamination was affected by the wood species, and the best adhesion occurred for the Cross Laminated Timber manufactured with Pinus elliottii (pino ellioti) and Acrocarpus fraxinifolius (lazcar) at the bonding pressure of 0,7 MPa. Cross Laminated Timber bonding pressure did not affect the percentage of wood in the shear test fractured surface, whereas higher density Cross Laminated Timber showed higher percentages.

Este estudio examinó la producción del cuidado en los servicios de salud, adoptando la metodología participativa “río de la vida”. Realizado en una comunidad que vive a la orilla de un río en el interior de estado de Amazonas, la investigación utilizó ese abordaje reflexivo, envolviendo la creación de un río con materiales artísticos, tales como lápices de colores, cartulina y otros. La técnica promovió la proximidad con las historias, trayectorias y el empoderamiento de agentes comunitarios, usuarios y cuidadores. Esa experiencia profunda proporcionó insights sobre los desafíos territoriales en el acceso a la salud en situaciones urgentes. La grabación de las narrativas durante trabajos colectivos sirvió como método de colecta de datos, facilitando el diálogo entre el equipo de salud y cuidadores, enriqueciendo la comprensión de las dinámicas regionales envueltas en el cuidado de emergencia.

This study examined the production of care in healthcare services, adopting the participatory methodology “river of life”. Conducted in a riverside community in the interior of the Amazonas region, the research employed this reflective approach, involving the creation of a river using artistic materials such as colored pencils and cardboard. The technique fostered closeness with the stories, trajectories, and empowerment of community agents, users, and caregivers. This profound experience provided insights into the territorial challenges in accessing healthcare during urgent situations. Recording narratives during collective work sessions served as a data collection method, facilitating dialogue between the healthcare team and caregivers, enriching the understanding of regional dynamics involved in emergency care.

Este estudo examinou a produção do cuidado nos serviços de saúde, adotando a metodologia participativa “rio da vida”. Realizado em uma comunidade ribeirinha no interior do Amazonas, a pesquisa utilizou essa abordagem reflexiva, envolvendo a criação de um rio com materiais artísticos, como lápis coloridos e cartolina. A técnica promoveu a proximidade com as histórias, trajetórias e empoderamento de agentes comunitários, usuários e cuidadores. Essa experiência profunda proporcionou insights sobre os desafios territoriais no acesso à saúde em situações urgentes. A gravação das narrativas durante os trabalhos coletivos serviu como método de coleta de dados, facilitando o diálogo entre a equipe de saúde e cuidadores; e enriquecendo a compreensão das dinâmicas regionais envolvidas no cuidado emergencial.

ABSTRACT Littoral cell angioma is an extremely rare splenic vascular tumor originating from the cells lining the splenic red pulp sinuses. Approximately 150 cases of littoral cell angioma have been reported since 1991. Its clinical manifestation is usually asymptomatic and is mostly diagnosed as an incidental finding through abdominal imaging. Herein, we present a case of littoral cell angioma in a 41-year-old woman with no previous comorbidities, which initially presented as a nonspecific splenic lesion diagnosed on imaging in the emergency room. The patient was treated through laparoscopic intervention. sinuses 15 1991 Herein 41yearold yearold 41 year old comorbidities room intervention 1 199 4 19

RESUMO Objetivou-se avaliar a suplementação de selênio orgânico (Se org.) em diferentes concentrações e de selênio inorgânico (Se inorg.) nas rações de codornas sobre o desempenho; qualidade dos ovos; e tempo e condições de armazenamento. No ensaio de desempenho foram utilizadas 360 codornas com 27 semanas de idade, distribuídas em delineamento inteiramente casualizado (DIC) composto por seis tratamentos: Ração Basal; 0,15; 0,30; 0,45; e 0,60 ppm de Se org. e 0,60 ppm de Se inorg. suplementados on top à ração basal, com seis repetições e dez aves por unidade experimental. Para avaliar o tempo e condições de armazenamento foram utilizados 720 ovos de codornas distribuídos em DIC, com esquema fatorial 6x5x2 (sendo seis tratamentos provenientes do ensaio de desempenho; cinco tempos de estocagem (7, 14, 21, 28 e 35 dias); e duas formas de estocagem (refrigerada e não refrigerada), com doze repetições contendo um ovo cada. Não houve efeito na suplementação de Se org. e Se inorg. nas rações sobre desempenho e qualidade dos ovos. Houve aumento linear na concentração de Se nos ovos de codornas alimentadas com níveis crescentes deste nutriente. Houve efeito da suplementação com selênio sobre o tempo de estocagem na qualidade de ovos mantidos sob refrigeração e em temperatura ambiente. Conclui-se que a suplementação, on top, de níveis entre 0,15 e 0,60 ppm de selênio nas formas orgânica ou inorgânica, não altera o desempenho das codornas, acentuando, contudo, a deposição desse mineral nos ovos, favorecendo a manutenção da qualidade ao longo do tempo de armazenamento. Objetivouse Objetivou se org inorg 36 2 idade DIC (DIC Basal 015 0 15 0,30 030 30 0,45 045 45 060 60 0,6 basal experimental 72 xx x 6x5x sendo 7, 7 (7 14 21 3 dias dias) refrigerada refrigerada, , refrigerada) cada nutriente ambiente Concluise Conclui 0,1 inorgânica acentuando contudo 01 1 0,3 03 0,4 04 4 06 6 0, (

ABSTRACT The objective of this study was to assess the impact of supplementing quail diets with organic selenium (Se) at various concentrations and inorganic Se on performance, egg quality, and storage time under different conditions. In the performance trial, 360 quail aged 27 weeks were included in a completely randomized design comprising six treatments: Basal Diet; 0.15, 0.30, 0.45, and 0.60 ppm of organic Se; and 0.60 ppm of inorganic Se, supplemented “on top” of the basal diet. Six replications were used, each with 10 birds per experimental unit. For the evaluation of storage time and conditions, 720 quail eggs were employed in a completely randomized design. The design featured a 6×5×2 factorial arrangement consisting of six treatments derived from the performance trial, five storage times (7, 14, 21, 28, and 35 days), and two storage forms (refrigerated and non-refrigerated). Each replication contained one egg, totaling 12 replications. Results indicated no significant effect of organic or inorganic Se supplementation in the diets on performance or egg quality. However, Se concentration increased linearly in eggs from quail fed increasing levels of this nutrient. Selenium supplementation affected storage time and egg quality under refrigerated and room-temperature conditions. In conclusion, on-top Se supplementation at concentrations ranging from 0.15 to 0.60 ppm, whether in organic or inorganic forms, does not impact quail performance. Nevertheless, it leads to increased Se deposition in eggs, contributing to the maintenance of egg quality throughout the storage period. (Se conditions trial 36 2 Diet 015 0 15 030 30 0.30 045 45 0.45 060 60 0.6 top diet used 1 unit 72 652 6 5 6×5× 7, 7 (7 14 21 28 3 days, days , days) nonrefrigerated. nonrefrigerated non . non-refrigerated) However nutrient roomtemperature room temperature conclusion ontop 0.1 Nevertheless period 01 03 0.3 04 4 0.4 06 0. 65 6×5 ( non-refrigerated 6×

Abstract Endometriosis is a complex disease that affects 10-15% of women of reproductive age. Familial studies show that relatives of affected patients have a higher risk of developing the disease, implicating a genetic role for this disorder. Little is known about the impact of germline genomic copy number variant (CNV) polymorphisms on the heredity of the disease. In this study, we describe a rare CNV identified in two sisters with familial endometriosis, which contain genes that may increase the susceptibility and progression of this disease. We investigated the presence of CNVs from the endometrium and blood of the sisters with endometriosis and normal endometrium of five women as controls without the disease using array-CGH through the Agilent 2x400K platform. We excluded common CNVs that were present in the database of genomic variation. We identified, in both sisters, a rare CNV gain affecting 113kb at band 3q12.2 involving two candidate genes: ADGRG7 and TFG. The CNV gain was validated by qPCR. ADGRG7 is located at 3q12.2 and encodes a G protein-coupled receptor influencing the NF-kappaβ pathway. TFG participates in chromosomal translocations associated with hematologic tumor and soft tissue sarcomas, and is also involved in the NF-kappa B pathway. The CNV gain in this family provides a new candidate genetic marker for future familial endometriosis studies. Additional longitudinal studies of affected families must confirm any associations between this rare CNV gain and genes involved in the NF-kappaβ pathway in predisposition to endometriosis. 1015% 1015 10 15% 15 10-15 age disorder (CNV study arrayCGH array CGH xK x K platform variation kb 3q122 q 3q12 2 3q12. ADGRG qPCR proteincoupled protein coupled NFkappaβ NF kappaβ sarcomas NFkappa kappa 101 1 10-1 3q1 10- 3q

Resumo A doença cerebrovascular extracraniana tem sido intensamente investigada em todo o mundo, sendo tema de suma importância para os cirurgiões vasculares. A presente Diretriz foi elaborada pela Sociedade Brasileira de Angiologia e Cirurgia Vascular (SBACV) em sucessão à Diretriz de 2015. As doenças de etiologia não ateroscleróticas não foram incluídas nesse documento. O objetivo desta Diretriz é congregar as evidências mais robustas nessa área para auxiliar os especialistas no processo decisório do tratamento. Foi utilizada a metodologia AGREE II e o sistema da Sociedade Europeia de Cardiologia para as recomendações e níveis de evidências. As recomendações foram graduadas de I a III, e os níveis de evidência classificados em A, B e C. A presente Diretriz foi dividida em 11 capítulos, que tratam dos vários aspectos da doença cerebrovascular extracraniana: diagnóstico, tratamentos e complicações, de forma atualizada e com as recomendações propostas pela SBACV. mundo vasculares SBACV (SBACV 2015 documento tratamento III C 1 capítulos diagnóstico complicações 201 20 2

Abstract Extracranial cerebrovascular disease has been the subject of intense research throughout the world, and is of paramount importance for vascular surgeons. This guideline, written by the Brazilian Society of Angiology and Vascular Surgery (SBACV), supersedes the 2015 guideline. Non-atherosclerotic carotid artery diseases were not included in this document. The purpose of this guideline is to bring together the most robust evidence in this area in order to help specialists in the treatment decision-making process. The AGREE II methodology and the European Society of Cardiology system were used for recommendations and levels of evidence. The recommendations were graded from I to III, and levels of evidence were classified as A, B, or C. This guideline is divided into 11 chapters dealing with the various aspects of extracranial cerebrovascular disease: diagnosis, treatments and complications, based on up-to-date knowledge and the recommendations proposed by SBACV. world surgeons SBACV, SBACV , (SBACV) 201 Nonatherosclerotic Non atherosclerotic document decisionmaking decision making process III A B C 1 diagnosis complications uptodate up date (SBACV 20 2

Abstract Deep purple is an open-pollinated variety, well adapted to tropical conditions, developed to induce maternal haploids in maize. The founders were W23, Stock6, and an experimental tropical maize population. The inducer population inherits the dominant the R1-nj marker, and the expected real haploid induction rate is 3%. openpollinated open pollinated variety conditions W23 W Stock6 Stock R1nj Rnj R1 nj R marker 3 3% W2

Resumo O pé diabético corresponde a uma interação entre fatores anatômicos, vasculares e neurológicos que representam um desafio na prática clínica. O objetivo deste trabalho foi compilar as principais evidências científicas com base em uma revisão das principais diretrizes, além de artigos publicados nas plataformas Embase, Lilacs e PubMed. O sistema da Sociedade Européia de Cardiologia foi utilizado para desenvolver classes de recomendação e níveis de evidência. Os temas foram divididos em seis capítulos (Capítulo 1-Prevenção de úlceras nos pés de pessoas com diabetes; Capítulo 2-Alívio da pressão de úlceras nos pés de pessoas com diabetes; Capítulo 3-Classificações das úlceras do pé diabético; Capítulo 4-Pé diabético e a doença arterial periférica; Capítulo 5-Infecção e o pé diabético; Capítulo 6-Neuroartropatia de Charcot). A versão atual das Diretrizes sobre pé diabético apresenta importantes recomendações para prevenção, diagnóstico, tratamento e seguimento dos pacientes com pé diabético, oferecendo um guia objetivo para prática médica. anatômicos clínica diretrizes Embase PubMed evidência 1Prevenção Prevenção 1 diabetes 2Alívio Alívio 2 3Classificações Classificações 3 4Pé Pé 4 periférica 5Infecção Infecção 5 6Neuroartropatia Neuroartropatia 6 Charcot. Charcot . Charcot) prevenção diagnóstico médica

Abstract The diabetic foot interacts with anatomical, vascular, and neurological factors that challenge clinical practice. This study aimed to compile the primary scientific evidence based on a review of the main guidelines, in addition to articles published on the Embase, Lilacs, and PubMed platforms. The European Society of Cardiology system was used to develop recommendation classes and levels of evidence. The themes were divided into six chapters (Chapter 1 - Prevention of foot ulcers in people with diabetes; Chapter 2 - Pressure relief from foot ulcers in people with diabetes; Chapter 3 -Classifications of diabetic foot ulcers; Chapter 4 - Foot and peripheral artery disease; Chapter 5 - Infection and the diabetic foot; Chapter 6 - Charcot's neuroarthropathy). This version of the Diabetic Foot Guidelines presents essential recommendations for the prevention, diagnosis, treatment, and follow-up of patients with diabetic foot, offering an objective guide for medical practice. anatomical vascular practice guidelines Embase Lilacs platforms diabetes Classifications disease Charcots Charcot s neuroarthropathy. neuroarthropathy . neuroarthropathy) prevention diagnosis treatment followup follow up

Resumo O sistema de desinfecção solar, conhecido como SODIS (Solar Water Disinfection), é um método que envolve a exposição da água à radiação solar (luz UVA e calor) para eliminar microrganismos patogênicos. Coagulantes orgânicos extraídos da Moringa oleifera (T1) e Salvia hispanica (T2) foram usados em conjunto com o processo de filtração como auxiliares. Esse processo incluiu filtros de areia com tamanhos de partícula variando de 0,25 mm a 0,850 mm e uma manta geotêxtil não tecida colocada em sua base. Após passarem pelo processo de coagulação/floculação/sedimentação/filtração, as amostras foram expostas ao sol em um concentrador solar usando garrafas pintadas na metade de sua superfície (PR) e garrafas não pintadas (BR). Os parâmetros analisados incluíram propriedades físico-químicas como pH, condutividade elétrica, turbidez e cor aparente, bem como parâmetros microbiológicos, incluindo E. coli e coliformes totais. Os resultados das análises físico-químicas demonstraram a superioridade de T1 em termos de turbidez e cor aparente. Em relação às análises microbiológicas, as análises demostraram a remoção eficaz de E. coli e coliformes totais, com 100% de inativação observada nas amostras. Portanto, foi observado que a sequência de tratamento aplicada reduziu significativamente a carga microbiológica das amostras; contudo, não se pode afirmar com certeza se os coagulantes exerceram alguma influência nesse resultado. Solar Disinfection, Disinfection , Disinfection) luz calor patogênicos T (T1 T2 (T2 auxiliares 025 0 25 0,2 0850 850 0,85 base coagulaçãofloculaçãosedimentaçãofiltração coagulação floculação sedimentação coagulação/floculação/sedimentação/filtração PR (PR BR. BR . (BR) físicoquímicas físico químicas pH elétrica aparente microbiológicos E totais microbiológicas 100 Portanto contudo resultado (T 02 2 0, 085 85 0,8 (BR 10 08 8 1

Abstract Solar Water Disinfection, known as SODIS, is a treatment method involving the exposure of water to solar radiation (UVA light and heat) to eliminate pathogenic microorganisms. Organic coagulants extracted from Moringa oleifera (T1) and Salvia hispanica (T2) were used in conjunction with the filtration process as auxiliaries. This process included sand filters with particle sizes ranging from 0.25 mm to 0.850 mm and a non-woven geotextile placed at its base. After undergoing the coagulation/flocculation/sedimentation/filtration process, the samples were exposed to sunlight in a solar concentrator using bottles painted on half of their surface (PR) and unpainted bottles (BR). The analyzed parameters included physicochemical properties such as pH, electrical conductivity, turbidity, and apparent color, as well as microbiological parameters, including E. coli and total coliforms. The results of physicochemical analyses demonstrated the superiority of T1 in terms of turbidity and apparent color. Regarding microbiological analyses, they showed the effective removal of E. coli and total coliforms, with 100% inactivation observed in the samples. It was observed that the applied treatment sequence significantly reduced the microbiological load of the samples; however, it cannot be stated with certainty whether the coagulants exerted any influence on this result. Disinfection SODIS UVA heat microorganisms T (T1 T2 (T2 auxiliaries 025 0 25 0.2 0850 850 0.85 nonwoven non woven base coagulationflocculationsedimentationfiltration coagulation flocculation sedimentation PR (PR BR. BR . (BR) pH conductivity color E coliforms 100 however result (T 02 2 0. 085 85 0.8 (BR 10 08 8 1