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1.
Reproductive potential of the endangered land crab, Johngarthia lagostoma (H. Milne Edwards, 1837) (Brachyura: Gecarcinidae), from Trindade Island, Brazil
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Abstract An analysis of reproductive potential can elucidate significant aspects of the population biology and evolution of brachyuran crabs, providing a crucial baseline for conservation efforts concerning endangered species. Johngarthia lagostoma is an endemic species to Atlantic Oceanic islands (Rocas Atoll, Fernando de Noronha, Ascension, and Trindade), and it is classified as endangered (EN) in Brazilian territory according to IUCN criteria. Until now, the reproductive potential of this species has only been described for the Ascension Island population. Therefore, we assessed the reproductive effort and fecundity of J. lagostoma on Trindade Island. A total of 43 ovigerous females in the final stage of embryonic development were analyzed. Their egg masses were removed, weighed, and counted using a volumetric method. The carapace width ranged from 55.3 to 100.1 mm (mean ± standard deviation: 75.2 ± 13.1 mm). It exhibited a good fit and positive correlation with the egg weight and fecundity data but a poor fit and negative correlation with reproductive effort. The contrasting results of fecundity (82,938 ± 43,673 eggs) and reproductive effort (10.5 ± 1.5 %) recorded for J. lagostoma reveal a well-established population on Trindade Island compared to Ascension Island. These observations provide valuable information for proposing more effective management strategies for this endangered species across these Atlantic oceanic islands.
2.
Contamination by petroleum products on plant growth and soil microbiological indicators
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Silva, Kaline S. da
; Silva, Cydianne C. da
; Hernández, María C. R.
; Castellanos, Yansen M. H.
; Albuquerque, Márcio A. C.
; Silva, Francisca D. da
; Oliveira, Arthur A. S. de
; Silva, Daniel V.
.








RESUMO Compostos derivados de petróleo presentes no solo podem comprometer o crescimento das plantas e inibir o desenvolvimento da população microbiana. Esses contaminantes diminuem a porosidade do solo, dificultam a absorção de água e podem interromper processos metabólicos das plantas. Assim, nesta pesquisa buscou-se avaliar os efeitos da presença no solo de três hidrocarbonetos no solo sobre o crescimento e desenvolvimento de espécies forrageiras e nos indicadores microbiológicos do solo. O experimento foi realizado em casa de vegetação no delineamento experimental de blocos casualizados, com quatro repetições. Os tratamentos foram dispostos em fatorial de 5×4, sendo o primeiro fator constituído pelas espécies avaliadas (Pennisetum glaucum, Zea mays, Brachiaria ruziziensis, Panicum maximum e Sorghum bicolor), e o segundo fator correspondendo a presença dos contaminantes: benzeno, tolueno ou xileno e solo sem contaminante. As espécies foram cultivadas por 42 dias. A tolerância das espécies dependeu do tipo de contaminante presente no solo. A massa seca total da P. glaucum foi reduzida em 26%, 10% e 32% para o tolueno, benzeno e xileno, respectivamente. Z. mays teve o crescimento reduzido na presença do tolueno (13%) e do benzeno (21%). S. bicolor teve sua matéria seca aumentada em 58% com o xileno. B. ruziziensis e P. maximum foram tolerantes para todos os contaminantes. A magnitude dos efeitos dos contaminantes nos indicadores microbiológicos do solo dependeu da espécie cultivada. A tolerância das plantas e da comunidade microbiana do solo aos contaminantes depende da espécie forrageira utilizada e deve ser aspecto importante para a seleção de plantas para recuperação de áreas degradadas. Assim buscouse buscou se casualizados repetições 54 5 4 5×4 Pennisetum bicolor, , bicolor) dias P 26 26% 10 32 respectivamente Z 13% 13 (13% 21%. 21 21% . (21%) S 58 B cultivada degradadas 5× 2 1 3 (13 (21% (1 (21 ( (2
ABSTRACT Oil-derived compounds present in the soil can compromise plant growth and inhibit the development of the microbial population. These contaminants reduce soil porosity, hinder water absorption, and can disrupt plant metabolic processes. The aim of this research was to evaluate the effects of the presence of three hydrocarbons in the soil on the growth and development of forage species and on soil microbiological indicators. The experiment was carried out in a greenhouse using a randomized block design with four replications. Treatments were arranged in a 5×4 factorial, with the first factor consisting of the species evaluated (Pennisetum glaucum, Zea mays, Brachiaria ruziziensis, Panicum maximum and Sorghum bicolor) and the second factor corresponding to the presence of contaminants: benzene, toluene or xylene and soil without contaminants. The species were grown for 42 days. The tolerance of the species depended on the type of contaminant present in the soil. The total dry matter of P. glaucum was reduced by 26%, 10% and 32% for toluene, benzene and xylene, respectively. Z. mays had its growth reduced in the presence of toluene (13%) and benzene (21%). S. bicolor had its dry matter increased by 58% with xylene. B. ruziziensis and P. maximum were tolerant to all contaminants. The magnitude of the effects of contaminants on soil microbiological indicators depended on the species grown. The tolerance of plants and soil microbial community to contaminants depends on the forage species used and should be an important aspect when selecting plants to restore degraded areas. Oilderived Oil derived population porosity absorption processes replications 54 5 4 5× factorial Pennisetum days P 26 26% 10 32 respectively Z 13% 13 (13% 21%. 21 21% . (21%) S 58 B areas 2 1 3 (13 (21% (1 (21 ( (2
3.
Chemical Characterization and Evaluation of the Anti-Cancer Potential of Flowers from Fridericia platyphylla (Bignoniaceae) AntiCancer Anti Cancer Bignoniaceae (Bignoniaceae
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Rosário, Marcelino S. do
; Mannochio-Russo, Helena
; Santos, Ana L. P. dos
; Pinheiro, Aglaete A.
Vasconcelos, Luna N.
Santos, Ana Paula S. A.
Oliveira, Lila T. de
Martins, Monique M.
Andrade, Marcelo S. de
Nascimento, Maria D. S. B.
Bolzani, Vanderlan S.
Lima, Josélia A.
Rocha, Cláudia Q. da



In this study, we aimed to investigate the anticancer activity of the extract, fractions, and isolated compounds of the flowers of Fridericia platyphylla, and to characterize the bioactive compounds. The chemical diversity of the extracts and fractions was investigated using liquid chromatography coupled with high resolution mass spectrometry (LC-HRMS). We were able to annotate 26 compounds from the classes of flavones, flavonols, flavanones, isoflavones, and cinnamic acid and its derivatives. The dichloromethane fraction showed greater cytotoxicity at a concentration of 100 µg mL−1. In addition, the inhibitory concentrations of the dichloromethane fraction were 22.14 and 30.9 µg mL−1 for MCF-7 and MDA-MB-231 cell lines, respectively, and were capable of inhibiting tumor cell migration. Brachydins A and C were isolated from the dichloromethane fraction and showed the greatest cytotoxicity. The results obtained from this study show the potential biological effect of F. platyphylla flowers as a possible antitumor pharmacological agent. extract LCHRMS. LCHRMS LC HRMS . (LC-HRMS) 2 flavones flavonols flavanones isoflavones derivatives 10 mL1 mL 1 addition 2214 22 14 22.1 309 30 9 30. mL− MCF7 MCF 7 MCF- MDAMB231 MDAMB MDA MB 231 MDA-MB-23 lines respectively migration F agent (LC-HRMS 221 22. 3 MDAMB23 23 MDA-MB-2 MDAMB2 MDA-MB- MDA-MB
4.
DESIGN BIOINSPIRADO DE CORANTES
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Homem-de-Mello, Paula
; Souza, Ana Clara Gonzalez de
; Melo, Diêgo U.
; Mol, Gabriel S.
; Souza, Jhonathan R. De
; Carneiro, Leonardo M.
; Nobrega, Maíra G.
; Zanotto, Mateus
; Corrêa, Raissa Lohanna G. Q.
; Oliveira, Hueder P. M. de
; Bartoloni, Fernando H.
; Aoto, Yuri A.
; Coutinho-Neto, Mauricio D.
; Orestes, Ednilsom
.














The history of the discovery, use, and development of dyes is closely linked to the history of humanity itself. Among the first records of human civilization are cave paintings made from, e.g., fruits, plants, minerals, and insects. Over the centuries, using different techniques, colors have been given to all types of materials and products, from clothing to food. The chemicals responsible for colors are dyes - a vast collection of molecules of the most varied compositions, but which have in common the absorption of light within the visible window of the electromagnetic spectrum. This article aims not only to review the properties of some classes of natural dyes, their origins, and their applications but also to describe the various computational chemistry methods involved in designing new bio-inspired molecules. discovery use itself eg e g e.g. fruits plants minerals insects centuries techniques products food compositions spectrum origins bioinspired bio inspired e.g
5.
Molecular Dynamics of the Neutralizing Potential of Dimeric IgA Antibodies against SARS-CoV-2 Antigen SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- SARS-CoV
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Oliveira, Micael D. L.
; Silva, Jonathas N.
; Cordeiro, Isabelle B.
; Lima, Ana Carolina O.
; Faria, Nathalia S.
; Santos, Clarice S.
; Bessa, João A. H.
; Freitas, Rosiane de
; Malheiro, Adriana
Lima, Emersom S.
Oliveira, Kelson M. T.








The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) stands for being the most serious epidemic (so far) of the 21st century. However, only a few computational studies have investigated the molecular mechanisms underlying the neutralization of the spike protein by antibodies of different classes. Hence, bioinformatic methods were employed to unravel the factors contributing to the remarkable neutralization capacity exhibited by specific antibodies. Initially, crystallographic structures of IgA monomeric / dimeric, IgG, and IgM antibodies binding with the receptor-binding domain region of the SARS-CoV-2 spike protein were retrieved. Subsequently, rigid molecular docking and molecular dynamic simulations were performed over 100 ns with explicit water solvation. Lastly, an energy decomposition was conducted to estimate the binding affinity using the last frames from molecular dynamics. The results revealed a higher binding affinity for both monomeric and dimeric forms of IgA antibodies against the spike protein. Additionally, a greater number of hydrogen bonds were observed during their interaction with the spike protein, as well as greater structural instability along the time and especially a more thermodynamically favorable interaction affinity. In this way, the research contributes a small piece to the complex puzzle of understanding the humoral immune response induced by the SARS-CoV-2 virus. SARSCoV2 SARSCoV SARS CoV (SARS-CoV-2 so far st century However classes Hence Initially IgG receptorbinding receptor SARS-CoV- retrieved Subsequently 10 solvation Lastly dynamics Additionally way virus (SARS-CoV- SARS-CoV 1 (SARS-CoV
6.
Solid-Liquid Extraction with Low-Temperature Partitioning as an Alternative to Determinate Pesticide Residues in Teas SolidLiquid Solid Liquid LowTemperature Low Temperature
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Teixeira, Aline Maria
; Queiroz, Maria Eliana L. R. de
; Oliveira, André Fernando de
Rodrigues, Alessandra A. Z.
Novaes, Fábio Junior M.
Freitas, Jéssika F. de
Miranda, Liany D. L.


Methods used to determine pesticide residues in teas typically require several laborious steps for sample preparation before analysis. In this study, a simple method based on solid-liquid extraction with low-temperature partitioning (SLE/LTP) and analysis by gas chromatography coupled to mass spectrometry (GC-MS) was optimized and validated for the determination of pesticide residues (pirimiphos-methyl, flutriafol, cyproconazole, and bifenthrin) in dehydrated green tea leaves. After low-temperature partitioning (LTP), the extract in acetonitrile was subjected to a clean-up step using primary secondary amine (PSA) and octadecylsilane (C18) as sorbents for chlorophyll removal. The optimized SLE/LTP-GC-MS method was validated, and it proved to be effective and selective for extracting pesticides from green tea samples, presenting limit of detection (LOD) and limit of quantification (LOQ) of 0.015 and 0.050 mg kg-1, respectively. Recovery ranged between 81-111%, coefficients of variation were less than 16% and coefficients of determination (R2) were greater than 0.990. The optimized and validated method was applied to green tea and 13 other tea varieties sampled in South and Southeast regions of Brazil. The pesticides under study were detected in some of those samples at values higher than the maximum residue limits (MRLs) allowed by the European Union. solidliquid solid liquid lowtemperature low temperature SLE/LTP SLELTP SLE LTP (SLE/LTP GCMS GC MS (GC-MS pirimiphosmethyl, pirimiphosmethyl pirimiphos methyl, methyl (pirimiphos-methyl flutriafol cyproconazole bifenthrin leaves LTP, , (LTP) cleanup clean up PSA (PSA C18 C (C18 removal SLE/LTPGCMS SLELTPGCMS LOD (LOD LOQ (LOQ 0015 0 015 0.01 0050 050 0.05 kg1, kg1 kg 1, 1 kg-1 respectively 81111%, 81111 81 111%, 111 81-111% 16 R2 R (R2 0990 990 0.990 Brazil MRLs (MRLs Union (LTP C1 (C1 LTPGCMS 001 01 0.0 005 05 kg- 81111% 8111 8 111% 11 81-111 (R 099 99 0.99 (C 00 0. 811 81-11 09 9 0.9 81-1 81-
7.
Chemical Composition and Larvicidal Activity of Essential Oil Extracted from Anemia tomentosa (SAV.) Sw: Study Conducted in vitro and in silico SAV. SAV (SAV. Sw (SAV
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Jesus, Vilisaimon S. de
; Leite, Juliana L.
; Sousa, Jailan S.
; Barbosa, Fabricio S.
; Oliveira, Djalma M. de
; Barreto, Rubens S.
Soares, Wagner R. A.
Andrade, Bruno S.
Gualberto, Simone A.
Silva, Débora C. da
Guimarães, Isabelly D. S.
Silva, Luiza F.
Aguiar, Rosane M.





The essential oil extracted from Anemia tomentosa (EOAT) has shown larvicidal potential against Aedes aegypti, based on methods in vitro and in silico. Chromatographic and spectrometric techniques (gas chromatography-mass spectrometry (CG-MS), gas chromatography-flame ionization detector (GC-FID)), as well as mono and bidimensional nuclear magnetic resonance spectroscopy (NMR) were used to assess 10 essential oil components. Chemical composition of essential oil comprised 87.51% sesquiterpenes, with emphasis on presilphiperfolan-1-ol (42.13%) and silphiperfol-5-ene (19.47%). Larvicidal assay conducted in vitro with EOAT has evidenced potential cytotoxic activity up to 48 h exposure to it; mortality rate observed for A. aegypti larvae exposed to essential oil reached 100%. Study conducted in silico with chemical compounds deriving from the herein investigated plant species has evidenced its potential to inhibit acetylcholinesterase in A. aegypti. Activity of triquinane sesquiterpenes ranging from -6.8 to -8.2 kcal mol-1 stood out in comparison to that of temephos (-7.5 kcal mol-1). Chemical compounds identified in the investigated essential oil presented low human and environmental toxicity, as observed in absorption, distribution, metabolism and excretion, and toxicity (ADMETox) predictions. (EOAT chromatographymass chromatography mass CGMS, CGMS CG MS , (CG-MS) chromatographyflame flame GCFID, GCFID GC FID (GC-FID)) NMR (NMR 1 components 8751 87 51 87.51 presilphiperfolan1ol presilphiperfolanol presilphiperfolan ol 42.13% 4213 42 13 (42.13% silphiperfol5ene silphiperfolene silphiperfol 5 ene 19.47%. 1947 19.47% . 19 47 (19.47%) 4 it A 100 100% 6.8 68 6 8 -6. 8.2 82 2 -8. mol1 mol mol- 7.5 75 7 (-7. mol1. mol-1) absorption distribution excretion ADMETox (ADMETox predictions (CG-MS (GC-FID) 875 87.5 42.13 421 (42.13 194 19.47 (19.47% 6. -6 8. -8 7. (-7 (GC-FID 87. 42.1 (42.1 19.4 (19.47 - (- 42. (42. 19. (19.4 ( (42 (19. (4 (19 (1
8.
Beyond psychological individualism: rethinking clinical intuition in a post-Covid age individualism postCovid post Covid
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Resumo A ciência psicológica tem frequentemente insistido numa perspectiva individualista. Essa compreensão atomizada do self penetrou profundamente na psicologia, não apenas em seus ramos teóricos e experimentais, mas também na prática clínica. Aqui damos um exemplo de como desconstruir esse mito no nível micro: dentro do consultório do terapeuta. Para tanto, descrevemos o caso de Renata, de 28 anos, musicista e cantora. O relato do caso seguiu as recomendações da CARE. Sugerimos quatro níveis de análise: a. compreender e diagnosticar o Transtorno do Espectro do Autismo; b. neurodivergência e preconceito; c. autismo em mulheres: preconceito e mascaramento; d. autodirecionamento e intuição: superando a cegueira social. A conclusão aponta para a importância do autodirecionamento e da autotranscendência para acurácia clínica, quando há um problema de viés de gênero no Espectro do Autismo. Acima de tudo, o estudo de caso apresenta consequências mais amplas do despertar da psicoterapeuta enquanto agente de mudança social. individualista psicologia experimentais clínica micro terapeuta tanto Renata 2 anos cantora CARE análise Autismo b c mulheres mascaramento d intuição social tudo
Abstract Psychological science has often insisted on an individualistic perspective. Such atomised understanding of the self has moved deeply in psychology, not only in its theoretical and experimental arms, but also into clinical practice. Here an example of how to deconstruct such myth at the micro-level is given: within the therapist’s office space. Thereunto, we describe the case of Renata, 28 years old, musician and singer. The case report followed CARE recommendations. Four levels of analysis are suggested: a. understanding and diagnosing Autism Spectrum Disorder; b. neurodivergence and prejudice; c. autism in women: clinical bias and masking; d. self-directedness and intuition: overcoming social blindness. The conclusion points out to the importance of self-directedness and self-transcendence for clinical accuracy when there is a gender bias problem in autism spectrum. Above all, the case study presents broader consequences of the psychotherapist's awakening as an agent of social change. perspective psychology arms practice microlevel micro level given therapists therapist s space Thereunto Renata 2 old singer recommendations suggested Disorder b prejudice c women masking d selfdirectedness directedness intuition blindness selftranscendence transcendence spectrum all psychotherapists psychotherapist change
9.
Treinamento Físico Reduz a Inflamação e a Fibrose e Preserva a Função e a Perfusão Miocárdica em um Modelo de Cardiomiopatia Chagásica Crônica
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Damasceno, Thayrine R.
; Tanaka, Denise M.
; Magnani, Enrico F.
; Oliveira, Rafael D. B.
; Pereira, Danielle A. G.
; Vieira-Alves, Ildernandes
; Lemos, Virginia S.
; Cabeza, Jorge M.
; Fabricio, Camila G.
; Resende, Alessandra A.
; Gonçalves, Dawit A. P.
; Zanetti, Gustavo de Oliveira
; Carvalho, Eduardo E. Vieira de
; Simões, Marcus V.
; Oliveira, Luciano F. L.
.















Resumo Fundamento: A Cardiomiopatia Chagásica Crônica (CCC) é causada por um processo inflamatório induzido pelo Trypanosoma cruzi, que leva à miocardite com fibrose reativa e reparativa. A CCC progride com alterações de perfusão miocárdica e eventos histopatológicos que afetam a Aptidão Cardiorrespiratória (ACR). Objetivos: Avaliamos os efeitos do Treinamento Físico Aeróbico (TFA) na perfusão miocárdica e nos comprometimentos morfológicos e funcionais relacionados à inflamação e fibrose em hamsters sírios com CCC. Como objetivo secundário, analisamos as áreas de secção transversa do músculo esquelético. Métodos: Hamsters com CCC e seus respectivos controles foram divididos em quatro grupos: CCC sedentário, CCC-TFA, controle sedentário e controle TFA. Sete meses após a infecção, os animais foram submetidos à ecocardiografia, à cintilografia de perfusão miocárdica e ao teste de esforço cardiopulmonar. TFA de intensidade moderada foi realizado durante cinquenta minutos, cinco vezes por semana, por oito semanas. Posteriormente, os animais foram reavaliados. A análise histopatológica foi realizada após os procedimentos acima mencionados. O nível de significância foi estabelecido em 5% em todas as análises (p<0,05). Resultados: Animais com CCC sedentários apresentaram piores Defeitos de Perfusão Miocárdica (DPM) ao longo do tempo, Fração de Ejeção do Ventrículo Esquerdo (FEVE) reduzida, e apresentaram mais inflamação e fibrose quando comparados aos demais grupos (análise ANOVA mista). Por outro lado, o TFA foi capaz de mitigar a progressão do DPM, atenuar a inflamação e a fibrose e melhorar a eficiência da ACR em animais CCC-TFA. Conclusão: Nosso estudo demonstrou que o TFA melhorou a disfunção cardíaca, DPM e reduziu a inflamação e a fibrose em modelos de hamster com CCC. Além disso, os animais CCC-SED apresentaram atrofia do músculo esquelético, enquanto os animais CCC-TFA apresentaram a AST do músculo esquelético preservada. Compreender os efeitos da TFA nas dimensões fisiopatológicas da CCC é crucial para futuras pesquisas e intervenções terapêuticas. Fundamento (CCC cruzi reparativa ACR. . (ACR) Objetivos (TFA secundário Métodos CCCTFA, CCCTFA TFA, infecção ecocardiografia cardiopulmonar minutos semana semanas Posteriormente reavaliados mencionados 5 p<0,05. p005 p p<0,05 0 05 (p<0,05) Resultados (DPM tempo FEVE (FEVE reduzida mista. mista mista) lado CCCTFA. Conclusão cardíaca disso CCCSED SED preservada terapêuticas (ACR p00 p<0,0 (p<0,05 p0 p<0, (p<0,0 p<0 (p<0, p< (p<0 (p< (p
Abstract Background: Chronic Chagas cardiomyopathy (CCC) is caused by an inflammatory process induced by Trypanosoma cruzi, which leads to myocarditis with reactive and reparative fibrosis. CCC progresses with myocardial perfusion abnormalities and histopathological events that affect cardiorespiratory fitness (CRF). Objectives: We evaluated the effects of aerobic physical training (APT) on myocardial perfusion and on morphological and functional impairments related with inflammation and fibrosis in Syrian hamsters with CCC. As a secondary objective, we analyzed the cross-sectional areas of the skeletal muscle. Methods: Hamsters with CCC and their respective controls were divided into four groups: CCC sedentary, CCC-APT, sedentary control and APT control. Seven months after infection, the animals underwent echocardiography, myocardial perfusion scintigraphy and cardiopulmonary exercise testing. Moderate-intensity APT was performed for fifty minutes, five times a week, for eight weeks. Subsequently, the animals were reassessed. Histopathological analysis was conducted after the above-mentioned procedures. The level of significance was set at 5% in all analyses (p<0.05). Results: CCC sedentary animals presented worse myocardial perfusion defects (MPD) over time, reduced left ventricle ejection fraction (LVEF) and showed more inflammation and fibrosis when compared to other groups (mixed ANOVA analysis). Conversely, APT was able to mitigate the progression of MPD, ameliorate inflammation and fibrosis and improve CRF efficiency in CCC-APT animals. Conclusions: Our study demonstrated that APT ameliorated cardiac dysfunction, MPD, and reduced inflammation and fibrosis in CCC hamster models. Additionally, CCC-SED animals presented skeletal muscle atrophy while CCC-APT animals showed preserved skeletal muscle CSA. Understanding APT's effects on CCC's pathophysiological dimensions is crucial for future research and therapeutic interventions. Background (CCC cruzi CRF. . (CRF) Objectives (APT objective crosssectional cross sectional Methods CCCAPT, CCCAPT APT, infection echocardiography testing Moderateintensity Moderate intensity minutes week weeks Subsequently reassessed abovementioned above mentioned procedures 5 p<0.05. p005 p p<0.05 0 05 (p<0.05) Results MPD (MPD time LVEF (LVEF mixed analysis. analysis) Conversely Conclusions dysfunction models Additionally CCCSED SED CSA APTs s CCCs interventions (CRF p00 p<0.0 (p<0.05 p0 p<0. (p<0.0 p<0 (p<0. p< (p<0 (p< (p
10.
Growth and ionic homeostasis of custard apple seedlings irrigated with saline wastewater
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Souza, Antônia A. T.
; Mendonça, Vander
; Paiva, Emanoela P. de
; Melo, Bruna E. F.
; Souza Neta, Maria L. de
; Santos, Antônio S. dos
; Oliveira, Francisca das C. de
; Peixoto, Tayd D. C.
; Ferreira Neto, Miguel
; Sá, Francisco V. da S.
.










Revista Brasileira de Engenharia Agrícola e Ambiental
- Journal Metrics
RESUMO A pinheira (Annona squamosa L.) é uma frutífera sensível à salinidade. Uma das alternativas para minimizar os efeitos deletérios do estresse salino é a adoção de práticas de manejo da fertilização mineral, promovendo o aumento da tolerância da cultura aos sais. Portanto, o objetivo foi avaliar as doses de NPK para mitigar o estresse salino em mudas de pinheira irrigadas com água residual salina. O experimento foi realizado em casa de vegetação, em delineamento de blocos casualizados, em esquema fatorial 3 × 5, correspondendo a três águas de irrigação (água de abastecimento local de 0,53 dS m-1 de condutividade elétrica (controle); rejeito salino da dessalinização de 3,50 dS m-1; efluente de piscicultura de 3,50 dS m-1) e cinco proporções da recomendação de NPK (25, 50, 75, 100 e 125% da recomendação de fertilização), com quatro repetições. O crescimento, acúmulo de biomassa e nutrientes foram avaliados. A irrigação com rejeito salino e efluente de piscicultura restringe o crescimento das mudas de pinha, independentemente da dose de NPK utilizada. A homeostase iônica das mudas irrigadas com rejeito salino e efluente de piscicultura é otimizada pela fertilização com 50% da recomendação de NPK correspondente a 50, 150 e 75 mg de N, P2O5 e K2O dm-3, respectivamente. Para a produção de mudas irrigadas com água de abastecimento local, recomenda-se a dose de 75% de NPK, correspondente a 75, 225 e 112,5 mg de N, P2O5 e K2O dm-3, respectivamente. Annona L. L salinidade mineral sais Portanto salina vegetação casualizados 5 053 0 53 0,5 m1 m 1 m- controle (controle) 350 50 3,5 25, 25 (25 10 125 fertilização, , fertilização) repetições avaliados pinha utilizada 15 7 N PO P P2O KO K dm3, dm3 dm 3, dm-3 respectivamente recomendase recomenda se 22 1125 112 112, 05 0, (controle 35 2 (2 12 dm- 11 (
ABSTRACT Custard apple (Annona squamosa L.) is a sensitive fruit crop to salinity. One of the alternatives to minimize the deleterious effects of salt stress is adopting mineral fertilization management practices, promoting increased crop tolerance to salts. Therefore, the objective of the present study was to evaluate NPK doses to mitigate salt stress in custard apple seedlings irrigated with saline wastewater. The experiment was performed in a greenhouse, adopting a randomized block design in a 3 × 5 factorial scheme, corresponding to three irrigation waters (local-supply water of 0.53 dS m-1 electrical conductivity (control); desalination reject of 3.5 dS m-1; fish farming effluent of 3.5 dS m-1) and five proportions of the NPK recommendation (25, 50, 75, 100, and 125% of the fertilization recommendation), with four replicates. The growth, biomass accumulation, and nutrients were evaluated. Irrigation with desalination reject, and fish farming effluent restricted the growth of custard apple seedlings, regardless of the NPK dose used. The ionic homeostasis of seedlings irrigated with desalination reject and fish farming effluent is optimized by fertilization with 50% of the NPK recommendation corresponding to 50, 150, and 75 mg of N, P2O5, and K2O dm-3, respectively. For the production of seedlings irrigated with local-supply water, the dose of 75% NPK, corresponding to 75, 225, and 112.5 mg of N, P2O5, and K2O dm-3, respectively, is recommended. Annona L. L salinity practices salts Therefore wastewater greenhouse scheme localsupply local supply 053 0 53 0.5 m1 m 1 m- control (control) 35 3. 25, 25 (25 50 100 125 recommendation, , recommendation) replicates accumulation evaluated used 150 7 N P2O5 PO P O KO K dm3, dm3 dm 3, dm-3 respectively 225 1125 112 112. recommended 05 0. (control 2 (2 10 12 15 P2O dm- 22 11 (
11.
Ultra-Low-Dose Computed Tomography for Pneumonia in the Emergency Department: A Feasibility Study
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Bianco, Danilo P.
; Accorsi, Tarso A. D.
; Souza, Jose L.
; Mello, Eduardo S.
; Silva, Joselito A.
; Teles, Gustavo B. S.
; Chate, Rodrigo C.
; Santos, Andre R. C.
; Moron, Renato A.
; Mattos, Fernando R.
; Teles, Adriana Gusman
; Oliveira, Roger Pereira
; Almeida, Elizabeth Aparecida
; Zimmer, Paulo M.
; Funari, Marcelo B. G.
; Benveniste, Marcelo
; Szarf, Gilberto
.

















Resumo Introdução: O papel da tomografia computorizada torácica de ultrabaixa dose (ULDCT) em contexto de urgência é desconhecido. Objetivo: Este estudo avaliou a viabilidade da ULDCT em adultos na urgência com suspeita de pneumonia. Foram medidos a dose de radiação, o tempo entre a solicitação e os relatórios do exame, prescrições de antimicrobianos também foram correlacionadas. Métodos: Este estudo avaliou a viabilidade da ULDCT em adultos na urgência com suspeita de pneumonia. Foram medidas a dose de radiação, o tempo entre a solicitação e a disponibilização dos relatórios do exame, e também foram correlacionadas as prescrições de antimicrobianos. Entre outubro de 2017 e dezembro de 2018, incluímos prospectivamente adultos com suspeita de pneumonia adquirida na comunidade, sem diagnóstico definitivo por avaliação clínica. Os critérios de exclusão abrangeram condições clínicas que pudessem afetar a interpretação da imagem. Resultados: Foram incluídos 131 pacientes elegíveis (idade média de 43,5 anos; 57% homens) encaminhados para ULDCT. Dezoito (13,7%) foram excluídos. A dose média de radiação da ULDCT foi de 0,14 mSv. O intervalo de tempo entre a solicitação médica e o resultado da ULDCT foi de 43 minutos. Conclusão: A ULDCT mostrou-se viável para pacientes adultos com suspeita de pneumonia em contexto de urgência. Os relatórios foram disponibilizados num intervalo razoável e os resultados negativos foram associados a uma baixa taxa de prescrição de antibióticos.
Abstract Background: The role of ultra-low-dose chest CT (ULDCT) in the emergency department is unknown. Purpose: This study sought to examine feasibility of ULDCT in adults presenting to the emergency department for whom pneumonia was suspected. Radiation dose and time interval between medical request and ULDCT results were measured, antibiotic prescriptions were correlated. Methods: Between October 2017 and December 2018, we prospectively enrolled consecutive healthy adult patients in a single-center for whom community-acquired pneumonia was suspected and for whom no definitive diagnosis was possible by clinical judgment. Exclusion criteria comprised all chronic conditions that could impact severity and interpretation of image. Results: 131 eligible patients (mean age 43.5 years; 57% men) were enrolled to ULDCT. Eighteen (13.7%) patients were excluded. Average CT radiation dose was 0.14 mSv. Time interval between medical request and ultra-low-dose chest CT result was 43 minutes. Only 15.9% of patients with negative CT received antibiotics. Conclusion: Ultra-low-dose chest CT was feasible for almost all patients in a group of healthy adults presenting to the emergency department with suspected community-acquired pneumonia. Results were made available in a reasonable interval, and negative ones were associated with a low antibiotic prescription rate.
12.
Advances in Breast Cancer Drug Discovery: A Review of Therapeutic Strategies and Studies Involving Photosensitizers, Caged Xanthones and Thiosemicarbazones Derivatives
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Oliveira, Douglas D. S.
; Lapierre, Thibault J. W. Jacques Dit
; Silva, Fernanda C.
; Cunha, Ieda V.
; Souza, Rafael A. C.
; Matos, Patrícia A.
Almeida, Gustavo M.
Oliveira, Carolina G.
Araújo, Thaise G.
Tsubone, Tayana M.
Rezende Jr., Celso O.





Cancer is one of the major causes of death worldwide, and breast cancer is the most prevalent and deadly type among women. Despite the side effects and the phenomena of chemoresistance associated with the drugs involved, chemotherapy remains the main therapeutic strategy to combat and control breast cancer. Therefore, several new classes of compounds against breast cancer have been explored, in an effort to identify new drug candidates with alternative mechanisms of action. The principal results of such exploration, focusing on caged xanthones, thiosemicarbazones and photosensitizers, are presented in this review, along with the main aspects of the drug discovery process against breast cancer. More specifically, the design, structure-activity relationship investigations and anti-breast cancer properties of these three classes are described and discussed in this work.
13.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
Slipinski, Adam
Linzmeier, Adelita M.
Calor, Adolfo R.
Garda, Adrian A.
Kury, Adriano B.
Fernandes, Agatha C.S.
Agudo-Padrón, Aisur I.
Akama, Alberto
Silva Neto, Alberto M. da
Burbano, Alejandro L.
Menezes, Aleksandra
Pereira-Colavite, Alessandre
Anichtchenko, Alexander
Lees, Alexander C.
Bezerra, Alexandra M.R.
Domahovski, Alexandre C.
Pimenta, Alexandre D.
Aleixo, Alexandre L.P.
Marceniuk, Alexandre P.
Paula, Alexandre S. de
Somavilla, Alexandre
Specht, Alexandre
Camargo, Alexssandro
Newton, Alfred F.
Silva, Aline A.S. da
Santos, Aline B. dos
Tassi, Aline D.
Aragão, Allan C.
Santos, Allan P.M.
Migotto, Alvaro E.
Mendes, Amanda C.
Cunha, Amanda
Chagas Júnior, Amazonas
Sousa, Ana A.T. de
Pavan, Ana C.
Almeida, Ana C.S.
Peronti, Ana L.B.G.
Henriques-Oliveira, Ana L.
Prudente, Ana L.
Tourinho, Ana L.
Pes, Ana M.O.
Carmignotto, Ana P.
Wengrat, Ana P.G. da Silva
Dornellas, Ana P.S.
Molin, Anamaria Dal
Puker, Anderson
Morandini, André C.
Ferreira, André da S.
Martins, André L.
Esteves, André M.
Fernandes, André S.
Roza, André S.
Köhler, Andreas
Paladini, Andressa
Andrade, Andrey J. de
Pinto, Ângelo P.
Salles, Anna C. de A.
Gondim, Anne I.
Amaral, Antonia C.Z.
Rondón, Antonio A.A.
Brescovit, Antonio
Lofego, Antônio C.
Marques, Antonio C.
Macedo, Antonio
Andriolo, Artur
Henriques, Augusto L.
Ferreira Júnior, Augusto L.
Lima, Aurino F. de
Barros, Ávyla R. de A.
Brito, Ayrton do R.
Romera, Bárbara L.V.
Vasconcelos, Beatriz M.C. de
Frable, Benjamin W.
Santos, Bernardo F.
Ferraz, Bernardo R.
Rosa, Brunno B.
Sampaio, Brunno H.L.
Bellini, Bruno C.
Clarkson, Bruno
Oliveira, Bruno G. de
Corrêa, Caio C.D.
Martins, Caleb C.
Castro-Guedes, Camila F. de
Souto, Camilla
Bicho, Carla de L.
Cunha, Carlo M.
Barboza, Carlos A. de M.
Lucena, Carlos A.S. de
Barreto, Carlos
Santana, Carlos D.C.M. de
Agne, Carlos E.Q.
Mielke, Carlos G.C.
Caetano, Carlos H.S.
Flechtmann, Carlos H.W.
Lamas, Carlos J.E.
Rocha, Carlos
Mascarenhas, Carolina S.
Margaría, Cecilia B.
Waichert, Cecilia
Digiani, Celina
Haddad, Célio F.B.
Azevedo, Celso O.
Benetti, Cesar J.
Santos, Charles M.D. dos
Bartlett, Charles R.
Bonvicino, Cibele
Ribeiro-Costa, Cibele S.
Santos, Cinthya S.G.
Justino, Cíntia E.L.
Canedo, Clarissa
Bonecker, Claudia C.
Santos, Cláudia P.
Carvalho, Claudio J.B. de
Gonçalves, Clayton C.
Galvão, Cleber
Costa, Cleide
Oliveira, Cléo D.C. de
Schwertner, Cristiano F.
Andrade, Cristiano L.
Pereira, Cristiano M.
Sampaio, Cristiano
Dias, Cristina de O.
Lucena, Daercio A. de A.
Manfio, Daiara
Amorim, Dalton de S.
Queiroz, Dalva L. de
Queiroz, Dalva L. de
Colpani, Daniara
Abbate, Daniel
Aquino, Daniel A.
Burckhardt, Daniel
Cavallari, Daniel C.
Prado, Daniel de C. Schelesky
Praciano, Daniel L.
Basílio, Daniel S.
Bená, Daniela de C.
Toledo, Daniela G.P. de
Takiya, Daniela M.
Fernandes, Daniell R.R.
Ament, Danilo C.
Cordeiro, Danilo P.
Silva, Darliane E.
Pollock, Darren A.
Muniz, David B.
Gibson, David I.
Nogueira, David S.
Marques, Dayse W.A.
Lucatelli, Débora
Garcia, Deivys M.A.
Baêta, Délio
Ferreira, Denise N.M.
Rueda-Ramírez, Diana
Fachin, Diego A.
Souza, Diego de S.
Rodrigues, Diego F.
Pádua, Diego G. de
Barbosa, Diego N.
Dolibaina, Diego R.
Amaral, Diogo C.
Chandler, Donald S.
Maccagnan, Douglas H.B.
Caron, Edilson
Carvalho, Edrielly
Adriano, Edson A.
Abreu Júnior, Edson F. de
Pereira, Edson H.L.
Viegas, Eduarda F.G.
Carneiro, Eduardo
Colley, Eduardo
Eizirik, Eduardo
Santos, Eduardo F. dos
Shimbori, Eduardo M.
Suárez-Morales, Eduardo
Arruda, Eliane P. de
Chiquito, Elisandra A.
Lima, Élison F.B.
Castro, Elizeu B. de
Orlandin, Elton
Nascimento, Elynton A. do
Razzolini, Emanuel
Gama, Emanuel R.R.
Araujo, Enilma M. de
Nishiyama, Eric Y.
Spiessberger, Erich L.
Santos, Érika C.L. dos
Contreras, Eugenia F.
Galati, Eunice A.B.
Oliveira Junior, Evaldo C. de
Gallardo, Fabiana
Hernandes, Fabio A.
Lansac-Tôha, Fábio A.
Pitombo, Fabio B.
Dario, Fabio Di
Santos, Fábio L. dos
Mauro, Fabio
Nascimento, Fabio O. do
Olmos, Fabio
Amaral, Fabio R.
Schunck, Fabio
Godoi, Fábio S. P. de
Machado, Fabrizio M.
Barbo, Fausto E.
Agrain, Federico A.
Ribeiro, Felipe B.
Moreira, Felipe F.F.
Barbosa, Felipe F.
Silva, Fenanda S.
Cavalcanti, Fernanda F.
Straube, Fernando C.
Carbayo, Fernando
Carvalho Filho, Fernando
Zanella, Fernando C.V.
Jacinavicius, Fernando de C.
Farache, Fernando H.A.
Leivas, Fernando
Dias, Fernando M.S.
Mantellato, Fernando
Vaz-de-Mello, Fernando Z.
Gudin, Filipe M.
Albuquerque, Flávio
Molina, Flavio B.
Passos, Flávio D.
Shockley, Floyd W.
Pinheiro, Francielly F.
Mello, Francisco de A.G. de
Nascimento, Francisco E. de L.
Franco, Francisco L.
Oliveira, Francisco L. de
Melo, Francisco T. de V.
Quijano, Freddy R.B.
Salles, Frederico F.
Biffi, Gabriel
Queiroz, Gabriel C.
Bizarro, Gabriel L.
Hrycyna, Gabriela
Leviski, Gabriela
Powell, Gareth S.
Santos, Geane B. dos
Morse, Geoffrey E.
Brown, George
Mattox, George M.T.
Zimbrão, Geraldo
Carvalho, Gervásio S.
Miranda, Gil F.G.
Moraes, Gilberto J. de
Lourido, Gilcélia M.
Neves, Gilmar P.
Moreira, Gilson R.P.
Montingelli, Giovanna G.
Maurício, Giovanni N.
Marconato, Gláucia
Lopez, Guilherme E.L.
Silva, Guilherme L. da
Muricy, Guilherme
Brito, Guilherme R.R.
Garbino, Guilherme S.T.
Flores, Gustavo E.
Graciolli, Gustavo
Libardi, Gustavo S.
Proctor, Heather C.
Gil-Santana, Helcio R.
Varella, Henrique R.
Escalona, Hermes E.
Schmitz, Hermes J.
Rodrigues, Higor D.D.
Galvão Filho, Hilton de C.
Quintino, Hingrid Y.S.
Pinto, Hudson A.
Rainho, Hugo L.
Miyahira, Igor C.
Gonçalves, Igor de S.
Martins, Inês X.
Cardoso, Irene A.
Oliveira, Ismael B. de
Franz, Ismael
Fernandes, Itanna O.
Golfetti, Ivan F.
S. Campos-Filho, Ivanklin
Oliveira, Ivo de S.
Delabie, Jacques H.C.
Oliveira, Jader de
Prando, Jadila S.
Patton, James L.
Bitencourt, Jamille de A.
Silva, Janaina M.
Santos, Jandir C.
Arruda, Janine O.
Valderrama, Jefferson S.
Dalapicolla, Jeronymo
Oliveira, Jéssica P.
Hájek, Jiri
Morselli, João P.
Narita, João P.
Martin, João P.I.
Grazia, Jocélia
McHugh, Joe
Cherem, Jorge J.
Farias Júnior, José A.S.
Fernandes, Jose A.M.
Pacheco, José F.
Birindelli, José L.O.
Rezende, José M.
Avendaño, Jose M.
Duarte, José M. Barbanti
Ribeiro, José R. Inácio
Mermudes, José R.M.
Pujol-Luz, José R.
Santos, Josenilson R. dos
Câmara, Josenir T.
Teixeira, Joyce A.
Prado, Joyce R. do
Botero, Juan P.
Almeida, Julia C.
Kohler, Julia
Gonçalves, Julia P.
Beneti, Julia S.
Donahue, Julian P.
Alvim, Juliana
Almeida, Juliana C.
Segadilha, Juliana L.
Wingert, Juliana M.
Barbosa, Julianna F.
Ferrer, Juliano
Santos, Juliano F. dos
Kuabara, Kamila M.D.
Nascimento, Karine B.
Schoeninger, Karine
Campião, Karla M.
Soares, Karla
Zilch, Kássia
Barão, Kim R.
Teixeira, Larissa
Sousa, Laura D. do N.M. de
Dumas, Leandro L.
Vieira, Leandro M.
Azevedo, Leonardo H.G.
Carvalho, Leonardo S.
Souza, Leonardo S. de
Rocha, Leonardo S.G.
Bernardi, Leopoldo F.O.
Vieira, Letícia M.
Johann, Liana
Salvatierra, Lidianne
Oliveira, Livia de M.
Loureiro, Lourdes M.A. El-moor
Barreto, Luana B.
Barros, Luana M.
Lecci, Lucas
Camargos, Lucas M. de
Lima, Lucas R.C.
Almeida, Lucia M.
Martins, Luciana R.
Marinoni, Luciane
Moura, Luciano de A.
Lima, Luciano
Naka, Luciano N.
Miranda, Lucília S.
Salik, Lucy M.
Bezerra, Luis E.A.
Silveira, Luis F.
Campos, Luiz A.
Castro, Luiz A.S. de
Pinho, Luiz C.
Silveira, Luiz F.L.
Iniesta, Luiz F.M.
Tencatt, Luiz F.C.
Simone, Luiz R.L.
Malabarba, Luiz R.
Cruz, Luiza S. da
Sekerka, Lukas
Barros, Lurdiana D.
Santos, Luziany Q.
Skoracki, Maciej
Correia, Maira A.
Uchoa, Manoel A.
Andrade, Manuella F.G.
Hermes, Marcel G.
Miranda, Marcel S.
Araújo, Marcel S. de
Monné, Marcela L.
Labruna, Marcelo B.
Santis, Marcelo D. de
Duarte, Marcelo
Knoff, Marcelo
Nogueira, Marcelo
Britto, Marcelo R. de
Melo, Marcelo R.S. de
Carvalho, Marcelo R. de
Tavares, Marcelo T.
Kitahara, Marcelo V.
Justo, Marcia C.N.
Botelho, Marcia J.C.
Couri, Márcia S.
Borges-Martins, Márcio
Felix, Márcio
Oliveira, Marcio L. de
Bologna, Marco A.
Gottschalk, Marco S.
Tavares, Marcos D.S.
Lhano, Marcos G.
Bevilaqua, Marcus
Santos, Marcus T.T.
Domingues, Marcus V.
Sallum, Maria A.M.
Digiani, María C.
Santarém, Maria C.A.
Nascimento, Maria C. do
Becerril, María de los A.M.
Santos, Maria E.A. dos
Passos, Maria I. da S. dos
Felippe-Bauer, Maria L.
Cherman, Mariana A.
Terossi, Mariana
Bartz, Marie L.C.
Barbosa, Marina F. de C.
Loeb, Marina V.
Cohn-Haft, Mario
Cupello, Mario
Martins, Marlúcia B.
Christofersen, Martin L.
Bento, Matheus
Rocha, Matheus dos S.
Martins, Maurício L.
Segura, Melissa O.
Cardenas, Melissa Q.
Duarte, Mércia E.
Ivie, Michael A.
Mincarone, Michael M.
Borges, Michela
Monné, Miguel A.
Casagrande, Mirna M.
Fernandez, Monica A.
Piovesan, Mônica
Menezes, Naércio A.
Benaim, Natalia P.
Reategui, Natália S.
Pedro, Natan C.
Pecly, Nathalia H.
Ferreira Júnior, Nelson
Silva Júnior, Nelson J. da
Perioto, Nelson W.
Hamada, Neusa
Degallier, Nicolas
Chao, Ning L.
Ferla, Noeli J.
Mielke, Olaf H.H.
Evangelista, Olivia
Shibatta, Oscar A.
Oliveira, Otto M.P.
Albornoz, Pablo C.L.
Dellapé, Pablo M.
Gonçalves, Pablo R.
Shimabukuro, Paloma H.F.
Grossi, Paschoal
Rodrigues, Patrícia E. da S.
Lima, Patricia O.V.
Velazco, Paul
Santos, Paula B. dos
Araújo, Paula B.
Silva, Paula K.R.
Riccardi, Paula R.
Garcia, Paulo C. de A.
Passos, Paulo G.H.
Corgosinho, Paulo H.C.
Lucinda, Paulo
Costa, Paulo M.S.
Alves, Paulo P.
Roth, Paulo R. de O.
Coelho, Paulo R.S.
Duarte, Paulo R.M.
Carvalho, Pedro F. de
Gnaspini, Pedro
Souza-Dias, Pedro G.B.
Linardi, Pedro M.
Bartholomay, Pedro R.
Demite, Peterson R.
Bulirsch, Petr
Boll, Piter K.
Pereira, Rachel M.M.
Silva, Rafael A.P.F.
Moura, Rafael B. de
Boldrini, Rafael
Silva, Rafaela A. da
Falaschi, Rafaela L.
Cordeiro, Ralf T.S.
Mello, Ramon J.C.L.
Singer, Randal A.
Querino, Ranyse B.
Heleodoro, Raphael A.
Castilho, Raphael de C.
Constantino, Reginaldo
Guedes, Reinaldo C.
Carrenho, Renan
Gomes, Renata S.
Gregorin, Renato
Machado, Renato J.P.
Bérnils, Renato S.
Capellari, Renato S.
Silva, Ricardo B.
Kawada, Ricardo
Dias, Ricardo M.
Siewert, Ricardo
Brugnera, Ricaro
Leschen, Richard A.B.
Constantin, Robert
Robbins, Robert
Pinto, Roberta R.
Reis, Roberto E. dos
Ramos, Robson T. da C.
Cavichioli, Rodney R.
Barros, Rodolfo C. de
Caires, Rodrigo A.
Salvador, Rodrigo B.
Marques, Rodrigo C.
Araújo, Rodrigo C.
Araujo, Rodrigo de O.
Dios, Rodrigo de V.P.
Johnsson, Rodrigo
Feitosa, Rodrigo M.
Hutchings, Roger W.
Lara, Rogéria I.R.
Rossi, Rogério V.
Gerstmeier, Roland
Ochoa, Ronald
Hutchings, Rosa S.G.
Ale-Rocha, Rosaly
Rocha, Rosana M. da
Tidon, Rosana
Brito, Rosangela
Pellens, Roseli
Santos, Sabrina R. dos
Santos, Sandra D. dos
Paiva, Sandra V.
Santos, Sandro
Oliveira, Sarah S. de
Costa, Sávio C.
Gardner, Scott L.
Leal, Sebastián A. Muñoz
Aloquio, Sergio
Bonecker, Sergio L.C.
Bueno, Sergio L. de S.
Almeida, Sérgio M. de
Stampar, Sérgio N.
Andena, Sérgio R.
Posso, Sergio R.
Lima, Sheila P.
Gadelha, Sian de S.
Thiengo, Silvana C.
Cohen, Simone C.
Brandão, Simone N.
Rosa, Simone P.
Ribeiro, Síria L.B.
Letana, Sócrates D.
Santos, Sonia B. dos
Andrade, Sonia C.S.
Dávila, Stephane
Vaz, Stéphanie
Peck, Stewart B.
Christo, Susete W.
Cunha, Suzan B.Z.
Gomes, Suzete R.
Duarte, Tácio
Madeira-Ott, Taís
Marques, Taísa
Roell, Talita
Lima, Tarcilla C. de
Sepulveda, Tatiana A.
Maria, Tatiana F.
Ruschel, Tatiana P.
Rodrigues, Thaiana
Marinho, Thais A.
Almeida, Thaís M. de
Miranda, Thaís P.
Freitas, Thales R.O.
Pereira, Thalles P.L.
Zacca, Thamara
Pacheco, Thaynara L.
Martins, Thiago F.
Alvarenga, Thiago M.
Carvalho, Thiago R. de
Polizei, Thiago T.S.
McElrath, Thomas C.
Henry, Thomas
Pikart, Tiago G.
Porto, Tiago J.
Krolow, Tiago K.
Carvalho, Tiago P.
Lotufo, Tito M. da C.
Caramaschi, Ulisses
Pinheiro, Ulisses dos S.
Pardiñas, Ulyses F.J.
Maia, Valéria C.
Tavares, Valeria
Costa, Valmir A.
Amaral, Vanessa S. do
Silva, Vera C.
Wolff, Vera R. dos S.
Slobodian, Verônica
Silva, Vinícius B. da
Espíndola, Vinicius C.
Costa-Silva, Vinicius da
Bertaco, Vinicius de A.
Padula, Vinícius
Ferreira, Vinicius S.
Silva, Vitor C.P. da
Piacentini, Vítor de Q.
Sandoval-Gómez, Vivian E.
Trevine, Vivian
Sousa, Viviane R.
Sant’Anna, Vivianne B. de
Mathis, Wayne N.
Souza, Wesley de O.
Colombo, Wesley D.
Tomaszewska, Wioletta
Wosiacki, Wolmar B.
Ovando, Ximena M.C.
Leite, Yuri L.R.








ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
14.
Compressive lesions of the central nervous system in goats and sheep: A retrospective study of 11 cases in the Amazon biome sheep 1
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Barbosa, Camila C.
; Lopes, Cinthia T.A.
; Ferreira, Tatiane T.A.
; Oliveira, Carlos M.C.
; Campos, Karinny F.
; Bomjardim, Henrique A.
; Brito, Marilene F.
; Barbosa, José D.
.








RESUMO: O presente trabalho descreve, através de estudo retrospectivo, os achados epidemiológicos e clínico-patológicos em caprinos e ovinos com lesões compressivas no sistema nervoso central (SNC) no estado do Pará. O estudo retrospectivo compreendeu as observações realizadas em oito ovinos e três caprinos no período de 2005 a 2022, por meio da revisão dos arquivos de fichas clínicas de animais com lesões compressivas no SNC, atendidos pelo Hospital Veterinário Carlos Tokarnia do Instituto de Medicina Veterinária da Universidade Federal do Pará. Os animais atendidos com sintomatologia clínica foram submetidos a exames clínicos geral e específico do sistema nervoso. Todos os animais incluídos no estudo foram necropsiados. Os sinais clínicos variaram de acordo com a localização da lesão. Os achados de necropsia revelaram alterações como abscesso com osteomielite do corpo da vértebra com fratura patológica e compressão da medula espinhal; abscesso sub-meningeano no assoalho do crânio; hematoma subaracnoideo e alteração óssea congênita causando compressão medular e espondilite anquilosante. A realização de um minucioso exame clínico do SNC, associado aos achados de necropsia foi importante para caracterizar o quadro clínico, localizar a lesão e determinar a causa da enfermidade. O segmento medular mais acometido foi entre T3-L3. Torna-se importante incluir estas enfermidades na lista de diagnósticos diferenciais em animais de produção que apresentem sintomatologia nervosa. RESUMO descreve clínicopatológicos patológicos SNC (SNC Pará 200 2022 necropsiados espinhal submeningeano sub meningeano crânio anquilosante enfermidade T3L3. T3L3 TL T3 L3. L3 T L T3-L3 Tornase Torna se nervosa 20 202 T3L T3-L 2
ABSTRACT: This paper describes, within the framework of a retrospective study, the epidemiological and clinicopathological findings in goats and sheep with compressive lesions of the central nervous system (CNS) in Pará. This study included eight sheep and three goats from 2005 to 2022 by reviewing the clinical files of animals with CNS compressive lesions managed by the team of the Carlos Tokarnia Veterinary Hospital of the Institute of Veterinary Medicine of the Federal University of Pará. The animals with clinical signs were subjected to a general and specific clinical examination of the nervous system. All animals included in the study were necropsied, and the clinical signs were found to vary according to the location of the lesion. At necropsy, changes such as an abscess with osteomyelitis of the vertebral body with pathologic fracture and spinal cord compression, submeningeal abscess in the skull floor, subarachnoid hematoma, and congenital bone changes causing spinal cord compression and ankylosing spondylitis were noted. These findings indicate that a comprehensive clinical examination of the CNS in conjunction with necropsy findings is essential to characterize the clinical picture, localize the lesion, and determine the cause of the disease. The most affected medullary segment was between T3 and L3. Therefore, these diseases should be included in the list of differential diagnoses in farm animals with nervous system symptoms. ABSTRACT describes (CNS Pará 200 202 necropsied lesion floor hematoma noted picture disease T L3 L Therefore symptoms 20 2
15.
Adaptation of the normative rating procedure for the International Affective Picture System to a remote format
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Lemos, Thayane C.
; Silva, Laiz A. A.
; Gaspar, Sara D. J.
; Coutinho, Guilherme M. S.
; Stariolo, Jasmin B.
; Oliveira, Pedro G.M.R
; Conceicao, Lethicia S.
; Volchan, Eliane
; David, Isabel A.
.









Abstract Background The Self-Assessment Manikin (SAM), a pictorial scale for the measurement of pleasure and arousal dimensions of emotions, is one of the most applied tools in the emotion research field. Objective We present a detailed description of a remote method to collect affective ratings in response to pictures by using the SAM scale. Methods To empirically validate our remote method, we conducted a study using a digitized version of the SAM scale and delivered online didactic instructions that followed the normative rating procedure for the International Affective Picture System (IAPS) to the participants. We presented 70 pictures from the IAPS and an additional set of 22 food pictures to the participants. Results We found strong correlations between the ratings of IAPS pictures obtained in our sample and those reported by North American and Brazilian participants in previous in-person studies that applied the same pictures and methodology. We were also able to obtain an additional standardized set of food pictures. Conclusion The protocols described here may be useful for researchers interested in collecting remotely valid and reliable affecting ratings. SelfAssessment Self Assessment SAM, , (SAM) emotions field (IAPS 7 2 inperson person methodology (SAM
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