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1.
Treinamento Físico Reduz a Inflamação e a Fibrose e Preserva a Função e a Perfusão Miocárdica em um Modelo de Cardiomiopatia Chagásica Crônica
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Damasceno, Thayrine R.
; Tanaka, Denise M.
; Magnani, Enrico F.
; Oliveira, Rafael D. B.
; Pereira, Danielle A. G.
; Vieira-Alves, Ildernandes
; Lemos, Virginia S.
; Cabeza, Jorge M.
; Fabricio, Camila G.
; Resende, Alessandra A.
; Gonçalves, Dawit A. P.
; Zanetti, Gustavo de Oliveira
; Carvalho, Eduardo E. Vieira de
; Simões, Marcus V.
; Oliveira, Luciano F. L.
.
Resumo Fundamento: A Cardiomiopatia Chagásica Crônica (CCC) é causada por um processo inflamatório induzido pelo Trypanosoma cruzi, que leva à miocardite com fibrose reativa e reparativa. A CCC progride com alterações de perfusão miocárdica e eventos histopatológicos que afetam a Aptidão Cardiorrespiratória (ACR). Objetivos: Avaliamos os efeitos do Treinamento Físico Aeróbico (TFA) na perfusão miocárdica e nos comprometimentos morfológicos e funcionais relacionados à inflamação e fibrose em hamsters sírios com CCC. Como objetivo secundário, analisamos as áreas de secção transversa do músculo esquelético. Métodos: Hamsters com CCC e seus respectivos controles foram divididos em quatro grupos: CCC sedentário, CCC-TFA, controle sedentário e controle TFA. Sete meses após a infecção, os animais foram submetidos à ecocardiografia, à cintilografia de perfusão miocárdica e ao teste de esforço cardiopulmonar. TFA de intensidade moderada foi realizado durante cinquenta minutos, cinco vezes por semana, por oito semanas. Posteriormente, os animais foram reavaliados. A análise histopatológica foi realizada após os procedimentos acima mencionados. O nível de significância foi estabelecido em 5% em todas as análises (p<0,05). Resultados: Animais com CCC sedentários apresentaram piores Defeitos de Perfusão Miocárdica (DPM) ao longo do tempo, Fração de Ejeção do Ventrículo Esquerdo (FEVE) reduzida, e apresentaram mais inflamação e fibrose quando comparados aos demais grupos (análise ANOVA mista). Por outro lado, o TFA foi capaz de mitigar a progressão do DPM, atenuar a inflamação e a fibrose e melhorar a eficiência da ACR em animais CCC-TFA. Conclusão: Nosso estudo demonstrou que o TFA melhorou a disfunção cardíaca, DPM e reduziu a inflamação e a fibrose em modelos de hamster com CCC. Além disso, os animais CCC-SED apresentaram atrofia do músculo esquelético, enquanto os animais CCC-TFA apresentaram a AST do músculo esquelético preservada. Compreender os efeitos da TFA nas dimensões fisiopatológicas da CCC é crucial para futuras pesquisas e intervenções terapêuticas. Fundamento (CCC cruzi reparativa ACR. . (ACR) Objetivos (TFA secundário Métodos CCCTFA, CCCTFA TFA, infecção ecocardiografia cardiopulmonar minutos semana semanas Posteriormente reavaliados mencionados 5 p<0,05. p005 p p<0,05 0 05 (p<0,05) Resultados (DPM tempo FEVE (FEVE reduzida mista. mista mista) lado CCCTFA. Conclusão cardíaca disso CCCSED SED preservada terapêuticas (ACR p00 p<0,0 (p<0,05 p0 p<0, (p<0,0 p<0 (p<0, p< (p<0 (p< (p
Abstract Background: Chronic Chagas cardiomyopathy (CCC) is caused by an inflammatory process induced by Trypanosoma cruzi, which leads to myocarditis with reactive and reparative fibrosis. CCC progresses with myocardial perfusion abnormalities and histopathological events that affect cardiorespiratory fitness (CRF). Objectives: We evaluated the effects of aerobic physical training (APT) on myocardial perfusion and on morphological and functional impairments related with inflammation and fibrosis in Syrian hamsters with CCC. As a secondary objective, we analyzed the cross-sectional areas of the skeletal muscle. Methods: Hamsters with CCC and their respective controls were divided into four groups: CCC sedentary, CCC-APT, sedentary control and APT control. Seven months after infection, the animals underwent echocardiography, myocardial perfusion scintigraphy and cardiopulmonary exercise testing. Moderate-intensity APT was performed for fifty minutes, five times a week, for eight weeks. Subsequently, the animals were reassessed. Histopathological analysis was conducted after the above-mentioned procedures. The level of significance was set at 5% in all analyses (p<0.05). Results: CCC sedentary animals presented worse myocardial perfusion defects (MPD) over time, reduced left ventricle ejection fraction (LVEF) and showed more inflammation and fibrosis when compared to other groups (mixed ANOVA analysis). Conversely, APT was able to mitigate the progression of MPD, ameliorate inflammation and fibrosis and improve CRF efficiency in CCC-APT animals. Conclusions: Our study demonstrated that APT ameliorated cardiac dysfunction, MPD, and reduced inflammation and fibrosis in CCC hamster models. Additionally, CCC-SED animals presented skeletal muscle atrophy while CCC-APT animals showed preserved skeletal muscle CSA. Understanding APT's effects on CCC's pathophysiological dimensions is crucial for future research and therapeutic interventions. Background (CCC cruzi CRF. . (CRF) Objectives (APT objective crosssectional cross sectional Methods CCCAPT, CCCAPT APT, infection echocardiography testing Moderateintensity Moderate intensity minutes week weeks Subsequently reassessed abovementioned above mentioned procedures 5 p<0.05. p005 p p<0.05 0 05 (p<0.05) Results MPD (MPD time LVEF (LVEF mixed analysis. analysis) Conversely Conclusions dysfunction models Additionally CCCSED SED CSA APTs s CCCs interventions (CRF p00 p<0.0 (p<0.05 p0 p<0. (p<0.0 p<0 (p<0. p< (p<0 (p< (p
2.
Agronomic components of colored cotton cultivars as a function of potassium doses in the semiarid region
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Santos, Gisele L. dos
; Silva, Silvana F. da
; Silveira, Flávio P. da M.
; Oliveira, Pablo H. de A.
; Santos Júnior, José T. dos
; Souza, Ênio G. F.
; Lopes, Welder de A. R.
; Silveira, Lindomar M. da
; Barros Júnior, Aurélio P.
.
Revista Brasileira de Engenharia Agrícola e Ambiental
- Journal Metrics
RESUMO O potássio é um dos nutrientes mais importantes para o algodoeiro, sendo um elemento que participa de muitas funções fisiológicas na planta. Além disso, sua adequada disponibilidade favorece melhor desempenho produtivo à cultura. Logo, objetivou-se avaliar nesta pesquisa os componentes agronômicos em cultivares de algodão naturalmente colorido adubadas com doses de potássio no Semiárido brasileiro. Para isto, dois experimentos foram conduzidos na Fazenda Experimental Rafael Fernandes, localizada no município de Mossoró, RN, nos períodos de julho a novembro de 2019 e julho a novembro de 2021. O delineamento experimental foi o de blocos casualizados, arranjados em parcelas subdivididas, com quatro repetições. Nas parcelas, foram alocadas as doses de potássio (0, 60, 120, 180 e 240 kg ha-1 de K2O); e, nas subparcelas, as quatro cultivares de algodão naturalmente colorido (BRS Rubi, BRS Safira, BRS Verde e BRS Topázio). As cultivares de algodão colorido respondem à adubação potássica em função das condições edafoclimáticas as quais estão expostas. A cultivar BRS Topázio obteve maior produtividade e porcentagem de fibra nas duas safras de cultivo, destacando o seu potencial para a região. A dose de 240 kg ha-1 de K2O aumentou a produtividade do algodão colorido, em cultivo de segunda safra. As cultivares BRS Safira, BRS Rubi e BRS Verde foram pouco produtivas. algodoeiro planta disso cultura Logo objetivouse objetivou se brasileiro isto Fernandes Mossoró RN 201 2021 casualizados subdivididas repetições 0, 0 (0 60 120 18 24 ha1 ha 1 ha- KO K K2O) subparcelas Safira Topázio. . Topázio) expostas região safra produtivas 20 202 ( 6 12 2
ABSTRACT Potassium is one of the most important nutrients for the cotton plant, being an element that participates in many physiological functions. In addition, its adequate availability favors better production performance of the crop. Therefore, the objective of this study was to evaluate the agronomic components in naturally colored cotton cultivars fertilized with potassium doses in the Brazilian semiarid region. For this, two experiments were conducted at Rafael Fernandes Experimental Farm, located in the municipality of Mossoró, RN, from July to November 2019 and July to November 2021. The experimental design was randomized blocks, arranged in split plots, with four repetitions. Potassium doses (0, 60, 120, 180, and 240 kg ha-1 of K2O) were allocated in the plants; and four naturally colored cotton cultivars (BRS Rubi, BRS Safira, BRS Verde, and BRS Topázio) were allocated in the subplots. Colored cotton cultivars respond to potassium fertilization depending on the edaphoclimatic conditions to which they are exposed. BRS Topázio cultivar had higher lint cotton yield and fiber percentage in both growing seasons, highlighting its potential for the region. The dose of 240 kg ha-1 of K2O increased the yield of colored cotton, in second crop cultivation. The cultivars BRS Safira, BRS Rubi, and BRS Verde were not very productive. plant functions addition Therefore region Farm Mossoró RN 201 2021 blocks plots repetitions 0, 0 (0 60 120 180 24 ha1 ha 1 ha- KO K O plants Rubi Safira subplots exposed seasons cultivation productive 20 202 ( 6 12 18 2
3.
VESTÍGIOS DO DERRAME DE PETRÓLEO DE 2019: AVALIAÇÃO DA PRESENÇA DE HPA E BTEX EM PRODUTOS DE PESCA 2019 201 20 2
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Bertoldi, Crislaine F.
; Dolatto, Rafael G.
; Oliveira, Luiz F. L. de
; Reis, Lennon F.
; Canela, Maria C.
; Mélo, Julyanne T. B. de
; Rodrigues, Abinoan da S.
; Paim, Ana P.
; Grassi, Marco T.
.
The 2019 oil spill in Brazil caused widespread contamination in the Brazilian coast, posing risks to both animal and human health through seafood consumption. Therefore, this study aimed to evaluate seafood samples from different locations impacted by the oil spill. For this purpose, 44 samples underwent extraction processes for the determination of polycyclic aromatic hydrocarbons (PAH) and benzene, toluene, ethylbenzene, and xylene (BTEX). The BTEX compounds were undetected above the limit of detection (LOD) of 0.02 µg g−1 of wet mass. The LOD and limit of quantification (LOQ) for the PAH were 2 and 5 ng g−1, respectively. The range of recovery of PAH obtained from spiking was 39 ± 15.8 to 84 ± 5%. The concentration of PAH in the samples ranged from < LOQ to 17.5 ng g−1. Results suggested higher contamination levels in samples collected in Rio de Janeiro, with quantifications for 11 of the evaluated PAH. Benzo[a]pyrene and dibenzo[a,h]anthracene, both potentially carcinogenic, were found in 32 and 14% of samples, respectively. Therefore, additional coastal monitoring is advised to ensure seafood safety, given the potential PAH carcinogenicity, which could strain the Brazilian public health system. 201 coast consumption Therefore purpose 4 (PAH benzene toluene ethylbenzene BTEX. . (BTEX) (LOD 002 0 02 0.0 g1 g 1 g− mass (LOQ respectively 3 158 15 8 15. 5% 175 17 17. Janeiro Benzoapyrene Benzo a pyrene dibenzoa,hanthracene, dibenzoahanthracene dibenzo a,h anthracene, h anthracene dibenzo[a,h]anthracene carcinogenic 14 safety carcinogenicity system 20 (BTEX 00 0. dibenzoa hanthracene dibenzoa,hanthracene ah
4.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
; Linzmeier, Adelita M.
; Calor, Adolfo R.
; Garda, Adrian A.
; Kury, Adriano B.
; Fernandes, Agatha C.S.
; Agudo-Padrón, Aisur I.
; Akama, Alberto
; Silva Neto, Alberto M. da
; Burbano, Alejandro L.
; Menezes, Aleksandra
; Pereira-Colavite, Alessandre
; Anichtchenko, Alexander
; Lees, Alexander C.
; Bezerra, Alexandra M.R.
; Domahovski, Alexandre C.
; Pimenta, Alexandre D.
; Aleixo, Alexandre L.P.
; Marceniuk, Alexandre P.
; Paula, Alexandre S. de
; Somavilla, Alexandre
; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
; Santos, Aline B. dos
; Tassi, Aline D.
; Aragão, Allan C.
; Santos, Allan P.M.
; Migotto, Alvaro E.
; Mendes, Amanda C.
; Cunha, Amanda
; Chagas Júnior, Amazonas
; Sousa, Ana A.T. de
; Pavan, Ana C.
; Almeida, Ana C.S.
; Peronti, Ana L.B.G.
; Henriques-Oliveira, Ana L.
; Prudente, Ana L.
; Tourinho, Ana L.
; Pes, Ana M.O.
; Carmignotto, Ana P.
; Wengrat, Ana P.G. da Silva
; Dornellas, Ana P.S.
; Molin, Anamaria Dal
; Puker, Anderson
; Morandini, André C.
; Ferreira, André da S.
; Martins, André L.
; Esteves, André M.
; Fernandes, André S.
; Roza, André S.
; Köhler, Andreas
; Paladini, Andressa
; Andrade, Andrey J. de
; Pinto, Ângelo P.
; Salles, Anna C. de A.
; Gondim, Anne I.
; Amaral, Antonia C.Z.
; Rondón, Antonio A.A.
; Brescovit, Antonio
; Lofego, Antônio C.
; Marques, Antonio C.
; Macedo, Antonio
; Andriolo, Artur
; Henriques, Augusto L.
; Ferreira Júnior, Augusto L.
; Lima, Aurino F. de
; Barros, Ávyla R. de A.
; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
; Santos, Bernardo F.
; Ferraz, Bernardo R.
; Rosa, Brunno B.
; Sampaio, Brunno H.L.
; Bellini, Bruno C.
; Clarkson, Bruno
; Oliveira, Bruno G. de
; Corrêa, Caio C.D.
; Martins, Caleb C.
; Castro-Guedes, Camila F. de
; Souto, Camilla
; Bicho, Carla de L.
; Cunha, Carlo M.
; Barboza, Carlos A. de M.
; Lucena, Carlos A.S. de
; Barreto, Carlos
; Santana, Carlos D.C.M. de
; Agne, Carlos E.Q.
; Mielke, Carlos G.C.
; Caetano, Carlos H.S.
; Flechtmann, Carlos H.W.
; Lamas, Carlos J.E.
; Rocha, Carlos
; Mascarenhas, Carolina S.
; Margaría, Cecilia B.
; Waichert, Cecilia
; Digiani, Celina
; Haddad, Célio F.B.
; Azevedo, Celso O.
; Benetti, Cesar J.
; Santos, Charles M.D. dos
; Bartlett, Charles R.
; Bonvicino, Cibele
; Ribeiro-Costa, Cibele S.
; Santos, Cinthya S.G.
; Justino, Cíntia E.L.
; Canedo, Clarissa
; Bonecker, Claudia C.
; Santos, Cláudia P.
; Carvalho, Claudio J.B. de
; Gonçalves, Clayton C.
; Galvão, Cleber
; Costa, Cleide
; Oliveira, Cléo D.C. de
; Schwertner, Cristiano F.
; Andrade, Cristiano L.
; Pereira, Cristiano M.
; Sampaio, Cristiano
; Dias, Cristina de O.
; Lucena, Daercio A. de A.
; Manfio, Daiara
; Amorim, Dalton de S.
; Queiroz, Dalva L. de
; Queiroz, Dalva L. de
; Colpani, Daniara
; Abbate, Daniel
; Aquino, Daniel A.
; Burckhardt, Daniel
; Cavallari, Daniel C.
; Prado, Daniel de C. Schelesky
; Praciano, Daniel L.
; Basílio, Daniel S.
; Bená, Daniela de C.
; Toledo, Daniela G.P. de
; Takiya, Daniela M.
; Fernandes, Daniell R.R.
; Ament, Danilo C.
; Cordeiro, Danilo P.
; Silva, Darliane E.
; Pollock, Darren A.
; Muniz, David B.
; Gibson, David I.
; Nogueira, David S.
; Marques, Dayse W.A.
; Lucatelli, Débora
; Garcia, Deivys M.A.
; Baêta, Délio
; Ferreira, Denise N.M.
; Rueda-Ramírez, Diana
; Fachin, Diego A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Pádua, Diego G. de
; Barbosa, Diego N.
; Dolibaina, Diego R.
; Amaral, Diogo C.
; Chandler, Donald S.
; Maccagnan, Douglas H.B.
; Caron, Edilson
; Carvalho, Edrielly
; Adriano, Edson A.
; Abreu Júnior, Edson F. de
; Pereira, Edson H.L.
; Viegas, Eduarda F.G.
; Carneiro, Eduardo
; Colley, Eduardo
; Eizirik, Eduardo
; Santos, Eduardo F. dos
; Shimbori, Eduardo M.
; Suárez-Morales, Eduardo
; Arruda, Eliane P. de
; Chiquito, Elisandra A.
; Lima, Élison F.B.
; Castro, Elizeu B. de
; Orlandin, Elton
; Nascimento, Elynton A. do
; Razzolini, Emanuel
; Gama, Emanuel R.R.
; Araujo, Enilma M. de
; Nishiyama, Eric Y.
; Spiessberger, Erich L.
; Santos, Érika C.L. dos
; Contreras, Eugenia F.
; Galati, Eunice A.B.
; Oliveira Junior, Evaldo C. de
; Gallardo, Fabiana
; Hernandes, Fabio A.
; Lansac-Tôha, Fábio A.
; Pitombo, Fabio B.
; Dario, Fabio Di
; Santos, Fábio L. dos
; Mauro, Fabio
; Nascimento, Fabio O. do
; Olmos, Fabio
; Amaral, Fabio R.
; Schunck, Fabio
; Godoi, Fábio S. P. de
; Machado, Fabrizio M.
; Barbo, Fausto E.
; Agrain, Federico A.
; Ribeiro, Felipe B.
; Moreira, Felipe F.F.
; Barbosa, Felipe F.
; Silva, Fenanda S.
; Cavalcanti, Fernanda F.
; Straube, Fernando C.
; Carbayo, Fernando
; Carvalho Filho, Fernando
; Zanella, Fernando C.V.
; Jacinavicius, Fernando de C.
; Farache, Fernando H.A.
; Leivas, Fernando
; Dias, Fernando M.S.
; Mantellato, Fernando
; Vaz-de-Mello, Fernando Z.
; Gudin, Filipe M.
; Albuquerque, Flávio
; Molina, Flavio B.
; Passos, Flávio D.
; Shockley, Floyd W.
; Pinheiro, Francielly F.
; Mello, Francisco de A.G. de
; Nascimento, Francisco E. de L.
; Franco, Francisco L.
; Oliveira, Francisco L. de
; Melo, Francisco T. de V.
; Quijano, Freddy R.B.
; Salles, Frederico F.
; Biffi, Gabriel
; Queiroz, Gabriel C.
; Bizarro, Gabriel L.
; Hrycyna, Gabriela
; Leviski, Gabriela
; Powell, Gareth S.
; Santos, Geane B. dos
; Morse, Geoffrey E.
; Brown, George
; Mattox, George M.T.
; Zimbrão, Geraldo
; Carvalho, Gervásio S.
; Miranda, Gil F.G.
; Moraes, Gilberto J. de
; Lourido, Gilcélia M.
; Neves, Gilmar P.
; Moreira, Gilson R.P.
; Montingelli, Giovanna G.
; Maurício, Giovanni N.
; Marconato, Gláucia
; Lopez, Guilherme E.L.
; Silva, Guilherme L. da
; Muricy, Guilherme
; Brito, Guilherme R.R.
; Garbino, Guilherme S.T.
; Flores, Gustavo E.
; Graciolli, Gustavo
; Libardi, Gustavo S.
; Proctor, Heather C.
; Gil-Santana, Helcio R.
; Varella, Henrique R.
; Escalona, Hermes E.
; Schmitz, Hermes J.
; Rodrigues, Higor D.D.
; Galvão Filho, Hilton de C.
; Quintino, Hingrid Y.S.
; Pinto, Hudson A.
; Rainho, Hugo L.
; Miyahira, Igor C.
; Gonçalves, Igor de S.
; Martins, Inês X.
; Cardoso, Irene A.
; Oliveira, Ismael B. de
; Franz, Ismael
; Fernandes, Itanna O.
; Golfetti, Ivan F.
; S. Campos-Filho, Ivanklin
; Oliveira, Ivo de S.
; Delabie, Jacques H.C.
; Oliveira, Jader de
; Prando, Jadila S.
; Patton, James L.
; Bitencourt, Jamille de A.
; Silva, Janaina M.
; Santos, Jandir C.
; Arruda, Janine O.
; Valderrama, Jefferson S.
; Dalapicolla, Jeronymo
; Oliveira, Jéssica P.
; Hájek, Jiri
; Morselli, João P.
; Narita, João P.
; Martin, João P.I.
; Grazia, Jocélia
; McHugh, Joe
; Cherem, Jorge J.
; Farias Júnior, José A.S.
; Fernandes, Jose A.M.
; Pacheco, José F.
; Birindelli, José L.O.
; Rezende, José M.
; Avendaño, Jose M.
; Duarte, José M. Barbanti
; Ribeiro, José R. Inácio
; Mermudes, José R.M.
; Pujol-Luz, José R.
; Santos, Josenilson R. dos
; Câmara, Josenir T.
; Teixeira, Joyce A.
; Prado, Joyce R. do
; Botero, Juan P.
; Almeida, Julia C.
; Kohler, Julia
; Gonçalves, Julia P.
; Beneti, Julia S.
; Donahue, Julian P.
; Alvim, Juliana
; Almeida, Juliana C.
; Segadilha, Juliana L.
; Wingert, Juliana M.
; Barbosa, Julianna F.
; Ferrer, Juliano
; Santos, Juliano F. dos
; Kuabara, Kamila M.D.
; Nascimento, Karine B.
; Schoeninger, Karine
; Campião, Karla M.
; Soares, Karla
; Zilch, Kássia
; Barão, Kim R.
; Teixeira, Larissa
; Sousa, Laura D. do N.M. de
; Dumas, Leandro L.
; Vieira, Leandro M.
; Azevedo, Leonardo H.G.
; Carvalho, Leonardo S.
; Souza, Leonardo S. de
; Rocha, Leonardo S.G.
; Bernardi, Leopoldo F.O.
; Vieira, Letícia M.
; Johann, Liana
; Salvatierra, Lidianne
; Oliveira, Livia de M.
; Loureiro, Lourdes M.A. El-moor
; Barreto, Luana B.
; Barros, Luana M.
; Lecci, Lucas
; Camargos, Lucas M. de
; Lima, Lucas R.C.
; Almeida, Lucia M.
; Martins, Luciana R.
; Marinoni, Luciane
; Moura, Luciano de A.
; Lima, Luciano
; Naka, Luciano N.
; Miranda, Lucília S.
; Salik, Lucy M.
; Bezerra, Luis E.A.
; Silveira, Luis F.
; Campos, Luiz A.
; Castro, Luiz A.S. de
; Pinho, Luiz C.
; Silveira, Luiz F.L.
; Iniesta, Luiz F.M.
; Tencatt, Luiz F.C.
; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
; Araújo, Marcel S. de
; Monné, Marcela L.
; Labruna, Marcelo B.
; Santis, Marcelo D. de
; Duarte, Marcelo
; Knoff, Marcelo
; Nogueira, Marcelo
; Britto, Marcelo R. de
; Melo, Marcelo R.S. de
; Carvalho, Marcelo R. de
; Tavares, Marcelo T.
; Kitahara, Marcelo V.
; Justo, Marcia C.N.
; Botelho, Marcia J.C.
; Couri, Márcia S.
; Borges-Martins, Márcio
; Felix, Márcio
; Oliveira, Marcio L. de
; Bologna, Marco A.
; Gottschalk, Marco S.
; Tavares, Marcos D.S.
; Lhano, Marcos G.
; Bevilaqua, Marcus
; Santos, Marcus T.T.
; Domingues, Marcus V.
; Sallum, Maria A.M.
; Digiani, María C.
; Santarém, Maria C.A.
; Nascimento, Maria C. do
; Becerril, María de los A.M.
; Santos, Maria E.A. dos
; Passos, Maria I. da S. dos
; Felippe-Bauer, Maria L.
; Cherman, Mariana A.
; Terossi, Mariana
; Bartz, Marie L.C.
; Barbosa, Marina F. de C.
; Loeb, Marina V.
; Cohn-Haft, Mario
; Cupello, Mario
; Martins, Marlúcia B.
; Christofersen, Martin L.
; Bento, Matheus
; Rocha, Matheus dos S.
; Martins, Maurício L.
; Segura, Melissa O.
; Cardenas, Melissa Q.
; Duarte, Mércia E.
; Ivie, Michael A.
; Mincarone, Michael M.
; Borges, Michela
; Monné, Miguel A.
; Casagrande, Mirna M.
; Fernandez, Monica A.
; Piovesan, Mônica
; Menezes, Naércio A.
; Benaim, Natalia P.
; Reategui, Natália S.
; Pedro, Natan C.
; Pecly, Nathalia H.
; Ferreira Júnior, Nelson
; Silva Júnior, Nelson J. da
; Perioto, Nelson W.
; Hamada, Neusa
; Degallier, Nicolas
; Chao, Ning L.
; Ferla, Noeli J.
; Mielke, Olaf H.H.
; Evangelista, Olivia
; Shibatta, Oscar A.
; Oliveira, Otto M.P.
; Albornoz, Pablo C.L.
; Dellapé, Pablo M.
; Gonçalves, Pablo R.
; Shimabukuro, Paloma H.F.
; Grossi, Paschoal
; Rodrigues, Patrícia E. da S.
; Lima, Patricia O.V.
; Velazco, Paul
; Santos, Paula B. dos
; Araújo, Paula B.
; Silva, Paula K.R.
; Riccardi, Paula R.
; Garcia, Paulo C. de A.
; Passos, Paulo G.H.
; Corgosinho, Paulo H.C.
; Lucinda, Paulo
; Costa, Paulo M.S.
; Alves, Paulo P.
; Roth, Paulo R. de O.
; Coelho, Paulo R.S.
; Duarte, Paulo R.M.
; Carvalho, Pedro F. de
; Gnaspini, Pedro
; Souza-Dias, Pedro G.B.
; Linardi, Pedro M.
; Bartholomay, Pedro R.
; Demite, Peterson R.
; Bulirsch, Petr
; Boll, Piter K.
; Pereira, Rachel M.M.
; Silva, Rafael A.P.F.
; Moura, Rafael B. de
; Boldrini, Rafael
; Silva, Rafaela A. da
; Falaschi, Rafaela L.
; Cordeiro, Ralf T.S.
; Mello, Ramon J.C.L.
; Singer, Randal A.
; Querino, Ranyse B.
; Heleodoro, Raphael A.
; Castilho, Raphael de C.
; Constantino, Reginaldo
; Guedes, Reinaldo C.
; Carrenho, Renan
; Gomes, Renata S.
; Gregorin, Renato
; Machado, Renato J.P.
; Bérnils, Renato S.
; Capellari, Renato S.
; Silva, Ricardo B.
; Kawada, Ricardo
; Dias, Ricardo M.
; Siewert, Ricardo
; Brugnera, Ricaro
; Leschen, Richard A.B.
; Constantin, Robert
; Robbins, Robert
; Pinto, Roberta R.
; Reis, Roberto E. dos
; Ramos, Robson T. da C.
; Cavichioli, Rodney R.
; Barros, Rodolfo C. de
; Caires, Rodrigo A.
; Salvador, Rodrigo B.
; Marques, Rodrigo C.
; Araújo, Rodrigo C.
; Araujo, Rodrigo de O.
; Dios, Rodrigo de V.P.
; Johnsson, Rodrigo
; Feitosa, Rodrigo M.
; Hutchings, Roger W.
; Lara, Rogéria I.R.
; Rossi, Rogério V.
; Gerstmeier, Roland
; Ochoa, Ronald
; Hutchings, Rosa S.G.
; Ale-Rocha, Rosaly
; Rocha, Rosana M. da
; Tidon, Rosana
; Brito, Rosangela
; Pellens, Roseli
; Santos, Sabrina R. dos
; Santos, Sandra D. dos
; Paiva, Sandra V.
; Santos, Sandro
; Oliveira, Sarah S. de
; Costa, Sávio C.
; Gardner, Scott L.
; Leal, Sebastián A. Muñoz
; Aloquio, Sergio
; Bonecker, Sergio L.C.
; Bueno, Sergio L. de S.
; Almeida, Sérgio M. de
; Stampar, Sérgio N.
; Andena, Sérgio R.
; Posso, Sergio R.
; Lima, Sheila P.
; Gadelha, Sian de S.
; Thiengo, Silvana C.
; Cohen, Simone C.
; Brandão, Simone N.
; Rosa, Simone P.
; Ribeiro, Síria L.B.
; Letana, Sócrates D.
; Santos, Sonia B. dos
; Andrade, Sonia C.S.
; Dávila, Stephane
; Vaz, Stéphanie
; Peck, Stewart B.
; Christo, Susete W.
; Cunha, Suzan B.Z.
; Gomes, Suzete R.
; Duarte, Tácio
; Madeira-Ott, Taís
; Marques, Taísa
; Roell, Talita
; Lima, Tarcilla C. de
; Sepulveda, Tatiana A.
; Maria, Tatiana F.
; Ruschel, Tatiana P.
; Rodrigues, Thaiana
; Marinho, Thais A.
; Almeida, Thaís M. de
; Miranda, Thaís P.
; Freitas, Thales R.O.
; Pereira, Thalles P.L.
; Zacca, Thamara
; Pacheco, Thaynara L.
; Martins, Thiago F.
; Alvarenga, Thiago M.
; Carvalho, Thiago R. de
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Henry, Thomas
; Pikart, Tiago G.
; Porto, Tiago J.
; Krolow, Tiago K.
; Carvalho, Tiago P.
; Lotufo, Tito M. da C.
; Caramaschi, Ulisses
; Pinheiro, Ulisses dos S.
; Pardiñas, Ulyses F.J.
; Maia, Valéria C.
; Tavares, Valeria
; Costa, Valmir A.
; Amaral, Vanessa S. do
; Silva, Vera C.
; Wolff, Vera R. dos S.
; Slobodian, Verônica
; Silva, Vinícius B. da
; Espíndola, Vinicius C.
; Costa-Silva, Vinicius da
; Bertaco, Vinicius de A.
; Padula, Vinícius
; Ferreira, Vinicius S.
; Silva, Vitor C.P. da
; Piacentini, Vítor de Q.
; Sandoval-Gómez, Vivian E.
; Trevine, Vivian
; Sousa, Viviane R.
; Sant’Anna, Vivianne B. de
; Mathis, Wayne N.
; Souza, Wesley de O.
; Colombo, Wesley D.
; Tomaszewska, Wioletta
; Wosiacki, Wolmar B.
; Ovando, Ximena M.C.
; Leite, Yuri L.R.
.
ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
5.
Estimated quantification of residual volume in vaccines supplies and its impact on the Brazilian health system
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PESSOA-GONÇALVES, YAGO MARCOS
; JESUS, ANA LUCIA G. DE
; CARVALHO, HENRIQUE C.P.
; DESIDÉRIO, CHAMBERTTAN S.
; TREVISAN, RAFAEL O.
; BOVI, WESLLEY G.
; SILVA, MARCOS VINÍCIUS DA
; OLIVEIRA, CARLO JOSÉ F.
.
Abstract Between 2017 and 2021, the Brazilian Unified Health System (BUHS) administered a total of 527,903,302 doses of immunizations. Each immunization results in the presence of a residual volume (RV) due to syringe dead space (DS). The International Organization for Standardization 7886-1 allows a DS of up to 0.07mL in sterile single-use hypodermic syringes with volumes less than 5mL. This study aims to quantify the DS of immunization devices used in Brazil, study the best combinations of needles and syringes to minimize RV, estimate the number of wasted doses from 2017 to 2021, and evaluate the impact on the BUHS. Pneumococcal 10 vaccine with a 25x6mm needle and a regular 1mL syringe exhibited a significantly higher average RV (0.0826mL) and waste rate (14.42%). It was observed that for some intramuscular vaccines, there is less waste when using a 20x5.5mm needle compared to a 25x6mm needle. The use of syringes with plunger stoppers that penetrate the syringe barrel, denoted as low dead space syringes, results in less RV and an estimated difference in the waste rate of approximately 10% compared to the regular syringe. The estimated number of wasted doses from 2017 to 2021 by BUHS is approximately 32 million doses. 201 (BUHS 527903302 527 903 302 527,903,30 immunizations (RV DS. . (DS) 78861 7886 1 7886- 007mL mL 0 07mL singleuse single 5mL Brazil xmm x mm 0.0826mL 00826mL 0826mL (0.0826mL 14.42%. 1442 14.42% 14 42 (14.42%) vaccines 20x55mm 20x5 5mm barrel 202 3 20 52790330 52 90 30 527,903,3 (DS 788 144 14.42 4 (14.42% 20x 2 5279033 5 9 527,903, 78 14.4 (14.42 527903 527,903 7 14. (14.4 52790 527,90 (14. 5279 527,9 (14 527, (1 (
6.
Sepsis by Plesiomonas shigelloides, Citrobacter freundii and Aeromonas jandaei in a green iguana (Iguana iguana) shigelloides Iguana
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Paranhos, Gabriel F.
; Oliveira Filho, Hodias S.
; Duarte, José L.C.
; Oliveira, Rafael L.
; Lima, Ewerton S.
; Fernandes, Arthur C.C.
; Firmino, Millena O.
; Silva, Welitânia I.
; Araújo, Jeann L.
.
RESUMO: Iguanídeos são suscetíveis a diversas infecções bacterianas, principalmente aquelas causadas por bactérias Gram-negativas. O desenvolvimento destas enfermidades em répteis está relacionado a manejos, condições sanitárias inadequadas e imunossupressão. Este estudo tem por objetivo descrever os aspectos anatomopatológicos e microbiológicos de um caso de coinfecção por Plesiomonas shigelloides, Citrobacter freundii e Aeromonas jandaei diagnosticado em uma iguana verde de vida livre (Iguana iguana). Macroscopicamente, as lesões localizavam-se principalmente em musculatura esquelética, miocárdio, duodeno e fígado, caracterizando-se por áreas branco-amareladas, multifocais, friáveis, e irregulares associadas à necrose e hemorragia. No histopatológico foram vistas estruturas bacilares basofílicas correspondentes a agregados bacterianos em músculo esquelético, miocárdio, parênquima hepático, rim, estômago e intestino delgado associados a áreas de trombose, necrose e hemorragia. O diagnóstico de sepse por P. shigelloides, C. freundii e A. jandaei foi confirmado pela técnica de ionização por dessorção a laser assistida por matriz com analisador por tempo de voo (MALDI-TOF) associada aos achados anatomopatológicos e microbiológicos observados neste caso. RESUMO bacterianas Gramnegativas. Gramnegativas Gram negativas. negativas Gram-negativas manejos imunossupressão shigelloides Iguana iguana. . iguana) Macroscopicamente localizavamse localizavam se esquelética miocárdio fígado caracterizandose caracterizando brancoamareladas, brancoamareladas branco amareladas, amareladas branco-amareladas multifocais friáveis hemorragia esquelético hepático rim trombose P C A MALDITOF MALDI TOF (MALDI-TOF
ABSTRACT: Iguanids are susceptible to several bacterial infections, especially those caused by Gram-negative bacteria. The development of these diseases in reptiles is related to management, inadequate sanitary conditions, and immunosuppression. This study aims to describe the anatomopathological and microbiological aspects of a case of co-infection by Plesiomonas shigelloides, Citrobacter freundii and Aeromonas jandaei diagnosed in a free-living green iguana (Iguana iguana). Macroscopically, the lesions were mainly located in skeletal muscle, myocardium, small intestine, and liver, characterized by white-yellowish, multifocal, friable, irregular areas associated with necrosis and hemorrhage. In the histopathological analysis, basophilic bacillary structures corresponding to bacterial aggregates were observed in the skeletal muscle, myocardium, hepatic parenchyma, kidney, stomach and small intestine associated with areas of thrombosis, necrosis and hemorrhage. The diagnosis of sepsis by P. shigelloides, C. freundii and A. jandaei was confirmed by matrix-assisted laser desorption/ionization time of flight (MALDI-TOF) associated with the anatomopathological and microbiological findings observed in this case. ABSTRACT infections Gramnegative Gram negative bacteria management conditions immunosuppression coinfection co infection shigelloides freeliving free living Iguana iguana. . iguana) Macroscopically muscle myocardium liver whiteyellowish, whiteyellowish white yellowish, yellowish white-yellowish multifocal friable hemorrhage analysis parenchyma kidney thrombosis P C A matrixassisted matrix assisted desorptionionization desorption ionization MALDITOF MALDI TOF (MALDI-TOF
7.
DNA barcode shows discordant cases among morphological and molecular species identification in Isbrueckerichthys (Siluriformes: Loricariidae) Siluriformes (Siluriformes Loricariidae
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Almeida, Rafael B. de
; Azambuja, Matheus
; Nogaroto, Viviane
; Oliveira, Claudio
; Roxo, Fábio F.
; Zawadzki, Cláudio H.
; Vicari, Marcelo R.
.
Resumo Isbrueckerichthys é um gênero de cascudinhos (Siluriformes: Loricariidae) que reúne cinco espécies morfológicas nas terras baixas da bacia do Ribeira de Iguape e nas terras altas da bacia do rio Tibagi. Apesar da validação das espécies morfológicas, estudos moleculares não tinham sido realizados para investigar o fluxo gênico e delimitação molecular das espécies. Para tanto, comparamos sequências da região COI associadas à identificação molecular por código de barras visando uma análise de delimitação de espécies e dados populacionais entre I. alipionis, I. epakmos, I. duseni, I. cf. duseni, I. saxicola e I. calvus. Os dados de distância genética K2P, a análise de delimitação molecular de espécies e ramos bem sustentados na árvore filogenética validam I. alipionis, I. epakmos e I. duseni, e sugere I. cf. duseni como unidade taxonômica operacional molecular. Ainda, não foram observadas diferenças entre I. saxicola e I. calvus. A discordância entre espécies moleculares e morfológicas pode ser devida à recente dispersão e diversificação de alguns representantes de Isbrueckerichthys na fronteira das bacias de Ribeira de Iguape e Tibagi. Características de isolamento da região serrana da bacia do Ribeira de Iguape e eventos de capturas de cabeceiras para terras altas foram utilizadas para explicar a dispersão e os casos de especiação incipiente em algumas linhagens de Isbrueckerichthys. Siluriformes (Siluriformes Loricariidae Tibagi tanto I alipionis cf calvus K2P KP K P Ainda
Abstract Isbrueckerichthys is a genus of armored catfish (Siluriformes: Loricariidae) with five species in the lowlands from the Ribeira de Iguape basin and in the uplands of the Tibagi River basin. Despite the validation of the morphological species, molecular data to investigate gene flow and species delimitation have not been completed for all species. For this purpose, we compared sequences of COI region associated with barcoding molecular identification, aiming for a species delimitation analysis and generating population data of I. alipionis, I. epakmos, I. duseni, I. cf. duseni, I. saxicola, and I. calvus. The K2P genetic distance, molecular species delimitation analysis, and well-sustained branches in the phylogenetic tree validate I. alipionis, I. epakmos, and I. duseni, and suggest I. cf. duseni as a valid molecular operational taxonomic unit. However, no differences were detected between I. saxicola and I. calvus. The discordance between molecular and morphological species may be due to the recent dispersal of some Isbrueckerichthys representatives at the border between the Ribeira de Iguape and Tibagi basins. The isolation features of the mountainous region of Ribeira de Iguape basin and headwaters captures to uplands are presented to explain the dispersion and the cases of incipient speciation in Isbrueckerichthys lineages. Siluriformes (Siluriformes Loricariidae purpose identification I alipionis epakmos cf calvus KP K P distance wellsustained well sustained unit However basins lineages
8.
Physicochemical and bioactive properties of Apis and stingless bee (Meliponini) honey from Brazilian Caatinga Meliponini (Meliponini
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Araújo, Filipe Gomes de
; Araújo, Nícolas Oliveira de
; Oliveira, Victor Rafael Leal de
; Leite, Ricardo Henrique de Lima
; Santos, Francisco Klebson Gomes dos
; Aroucha, Edna Maria Mendes
.
ABSTRACT. Since the composition of honey varies with the species of bee as well as flowering and geographical aspects, this study aimed to evaluate the physicochemical and bioactive properties of Apisand stingless bees’honey from the Brazilian Caatinga. Samples of different species of Apis mellifera L.Meliponini (Melipona subnitida, Frieseomellita varia, Melipona mandacaia, Plebeia sp.) and Apis mellifera L.werecollected from honey producersin the state of Rio Grande do Norte. Honey from A. mellifera and stingless bees showed physicochemical differences in some parameters, especially in moisture, free acidity, HMF, water activity, sugars and electric conductivity. There were no differences in color between honeys from A. mellifera and stingless bees. Honeys fromPlebeia sp., F. varia and A. mellifera showed higher antioxidant capacity followed by honeys fromM. mandacaia and M. subnitida. Flavonoids had little influence on the differentiation of antioxidant activities of stingless bees, while the opposite occurred with the phenolic content, where honeys with the highest levels of phenolic also showed higher antioxidant capacity. ABSTRACT aspects beeshoney Caatinga LMeliponini L Meliponini subnitida sp. sp Lwerecollected werecollected Norte A parameters moisture acidity HMF activity conductivity F fromM M content
9.
Development of prebiotic yogurt with addition of green-banana biomass (Musa spp.) greenbanana green banana Musa spp. spp
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COSTA, RAFAEL S.
; OLIVEIRA, RODRIGO F.
; HENRY, FÁBIO C.
; MELLO, WESLLEY A.O.
; GASPAR, CAROLINA R.
.
Anais da Academia Brasileira de Ciências
- Journal Metrics
Abstract This study evaluated the technological viability of yogurt with the addition of green-banana biomass (Musa spp.) considering the resistant starch (BBV) as a potential prebiotic ingredient and texture agent. Four yogurt formulations were prepared: control; 3% BBV; 5% BBV; and 10% BBV. They were subjected to analysis of resistant starch, lactose, fat, total dry extract, defatted dry extract, moisture, ash, proteins, pH and titratable acidity; syneresis analysis, instrumental texture and instrumental color. All four formulations met the requirements of the identity and quality regulation for fermented milks regarding the physicochemical and microbiological parameters. In the instrumental color analysis, in all treatments with added BBV, darkening was observed after 21 days, with a reduction of a* coordinate and an increase of b* coordinate. In the instrumental texture analysis, the yogurt in the Control treatment had the highest firmness (0.430 N) at 21 days among these treatments. Among the treatments with added BBV, the yogurt with 5% added BBV showed the best results for increasing the viability of lactic bacteria. It was found that yogurt with added BBV is a promising alternative in the elaboration of functional dairy products, adding value to the banana production chain by reducing the green fruit waste. greenbanana Musa spp. spp (BBV agent prepared control 3 5 10 lactose fat extract moisture ash proteins acidity parameters 2 b 0.430 0430 0 430 (0.43 N bacteria products waste 1 0.43 043 43 (0.4 0.4 04 4 (0. 0. (0 (
10.
Clinical and anatomopathological findings of lipid-related lesions in wild and pet birds from the State of Paraíba, Northeastern Brazil lipidrelated lipid related Paraíba
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Oliveira-Filho, Hodias S.
; Duarte, José L.C.
; Paranhos, Gabriel F.
; Oliveira, Rafael L.
; Farias, Roberto C.
; Araújo, Jeann Leal de
.
RESUMO: Doenças relacionadas à desordens no metabolismo dos lipídeos são reportadas em diversas ordens de aves, especialmente em piscítacídeos e incluem obesidade, aterosclerose, lipidose hepática, celomite por gema de ovo, lipomas, lipossarcomas, xantomas e xantogranulomas. Este estudo descreve aspectos epidemiológicos, clínicos e anatomopatológicos de 28 casos envolvendo lesões relacionadas a lipídeos em aves silvestres e pet no Nordeste Brasileiro. Os casos foram selecionados de um total de 313 aves atendidas entre 2018 e 2022 no Hospital Veterinário da UFPB. Tumores relacionados a lipídeos foram as lesões mais relatadas, seguido por obesidade, esteatose hepática, celomite por gema de ovo, aterosclerose e lipemia. A ordem Piscitaciforme foi a mais acometida e dieta errônea (Excesso de sementes de girassol, pão, bolacha, arroz, etc.) foi identificado como o principal fator de risco para o desenvolvimento das lesões, o que reforça a necessidade de advertir os tutores quanto a importância da alimentação adequada. Quarenta e nove por cento dos tumores relatados estavam na região pericloacal, o que torna lipomas e xantomas um diagnóstico diferencial importante para nódulos nessa localização em aves, principalmente psitacídeos. RESUMO obesidade hepática ovo lipossarcomas xantogranulomas epidemiológicos 2 Brasileiro 31 201 202 UFPB relatadas lipemia Excesso girassol pão bolacha arroz etc. etc adequada pericloacal psitacídeos 3 20
ABSTRACT: Diseases related to lipid metabolism disorders are reported in several orders of birds, especially in psittacines, and include obesity, atherosclerosis, hepatic lipidosis, egg yolk coelomitis, lipomas, liposarcomas, xanthomas and xanthogranulomas. This study describes epidemiological, clinical and anatomopathological aspects of 28 cases involving lipid-related lesions in wild and pet birds from Northeastern Brazil. The cases were selected from 313 avian patients referred to the UFPB Veterinary Hospital from 2018 to 2022. Lipid-related tumors were the most frequent lesions, followed by obesity, hepatic steatosis, egg yolk coelomitis, atherosclerosis and lipemia. The Psittaciformes order was the most affected, and an erroneous diet (excess consumption of sunflower seeds, bread, crackers, rice, etc.) was identified as the main risk factor for the development of these lesions, which reinforces the need to warn bird owners and caretakers about the importance of adequate nutrition. Forty-nine percent of the reported tumors were in the pericloacal region, which makes lipomas and xanthomas an important differential diagnosis for nodules in this location of birds, especially psittacids. ABSTRACT psittacines obesity lipidosis coelomitis liposarcomas xanthogranulomas epidemiological 2 lipidrelated Brazil 31 201 2022 Lipidrelated Lipid steatosis lipemia affected excess seeds bread crackers rice etc. etc nutrition Fortynine Forty nine region psittacids 3 20 202
11.
Model Membranes and Antimicrobial Activities of pH-Sensitive Copolymers pHSensitive pH Sensitive
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Saraiva, Greice K.
; Souza, Valdomiro V. de
; Oliveira, Luciana C. de
; Procópio, Alyne
; Martins, Maisa T.
; Aidar, Isabel N.
; Yi, Ronaldo C. F.
; Lacerda, Caroline D.
; Carretero, Gustavo P B.
; Lira, Rafael B. de
; Riske, Karin A.
; Salinas, Roberto K.
; Chaimovich, Hernan
; Florenzano, Fábio H.
; Cuccovia, Iolanda M.
.
Polymers are options as antimicrobials for skin protection, antifouling surfaces, and fabrics. Here we analyzed the interaction of polymers based on poly(methacrylate) (PMMA) and poly((dimethylamino ethyl) methacrylate) (PDMAEMA) with model membranes and bacteria. We used the homopolymers PMMA, PDMAEMA, and the diblock copolymer(s) prepared with different PMMAm:PDMAEMAn ratios (m/n). The interactions of PDMAEMA and PMMAm-b-PDMAEMAn with large unilamellar vesicles (LUVs) prepared with phosphatidylcholine and phosphatidylglycerol at different pHs, were analyzed by nuclear magnetic resonance (NMR), dynamic light scattering, and zeta potential. These polymers promoted LUVs leakage of a fluorescent probe (5,6-carboxyfluorescein) localized exclusively in the internal aqueous compartment. Interestingly, all copolymers exhibit a bell-shaped pH dependence for the polymer-induced LUVs leakage. The interaction of the positively charged polymers and the pH effect was also demonstrated using giant unilamellar vesicles. These copolymers inhibited bacterial growth in the micromolar range and can be used to prevent bacterial growth on surfaces. protection surfaces fabrics polymethacrylate poly methacrylate poly(methacrylate PMMA (PMMA polydimethylamino dimethylamino ethyl (PDMAEMA bacteria copolymer s copolymer(s PMMAmPDMAEMAn PMMAm PDMAEMAn m/n. mn m/n . m n (m/n) PMMAmbPDMAEMAn b (LUVs pHs NMR, NMR , (NMR) scattering potential 5,6carboxyfluorescein 56carboxyfluorescein carboxyfluorescein 5,6 5 6 (5,6-carboxyfluorescein compartment Interestingly bellshaped bell shaped polymerinduced polymer induced (m/n (NMR 6carboxyfluorescein 56 5,
12.
Effect of 2-chloro-N-(4-fluoro-3-nitrophenyl)acetamide in combination with antibacterial drugs against Klebsiella pneumoniae 2chloroN4fluoro3nitrophenylacetamide chloroNfluoronitrophenylacetamide 2 chloro N 4 fluoro 3 nitrophenyl acetamide chloroN nitrophenylacetamide
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CORDEIRO, LAÍSA V.
; SOUZA, HELIVALDO D.S.
; SOUSA, ALESON P.
; ANDRADE JÚNIOR, FRANCISCO P. DE
; FIGUEIREDO, PEDRO T.R. DE
; OLIVEIRA, RAFAEL F. DE
; ATHAYDE FILHO, PETRÔNIO F. DE
; OLIVEIRA-FILHO, ABRAHÃO A.
; LIMA, EDELTRUDES DE O.
.
Abstract Klebsiella pneumoniae is a species of Gram-negative bacteria related to a wide range of infections and high rates of drug resistance. The combined use of antibacterial agents is one of the strategies that has been analyzed in recent years as part of the alternatives in the treatment of drug-resistant infections. Recently, the antibacterial activity of of 2-chloro-N-(4-fluoro-3-nitrophenyl)acetamide has been demonstrated against K. pneumoniae, also indicating that this acetamide did not show significant cytotoxic potential in preliminary tests. Thus, it becomes an interesting substance for future studies that explore its antimicrobial capacity, including investigating its association with antibacterial drugs. Based on this, this research aimed to analyze the effects of the association of 2-chloro-N-(4-fluoro-3-nitrophenyl)acetamide (CFA) with ciprofloxacin, cefepime, ceftazidime, meropenem and imipenem against K. pneumoniae strains. The results showed additivity when the substance was combined with ciprofloxacin and cefepime, indifference when associated with ceftazidime and synergistic effect when combined with meropenem and imipenem. Thus, the acetamide was able to optimize the effects of antibacterial drugs, reducing the concentrations necessary to cause bacterial death. These data indicate a potential future clinical use of these combinations, and further studies are needed to analyze this viability. Gramnegative Gram negative resistance drugresistant resistant Recently 2chloroN4fluoro3nitrophenylacetamide chloroNfluoronitrophenylacetamide 2 chloro N 4 fluoro 3 nitrophenyl K tests Thus capacity drugs CFA (CFA cefepime strains death combinations viability chloroN nitrophenylacetamide
13.
Organic matter and shading on ion accumulation in soil cultivated with noni under salinity
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Souza, Maria C. M. R. de
; Oliveira, Letícia K. B. de
; Costa, Rafael S. da
; Menezes, Ademir S.
; Amorim, Aiala V.
; Lacerda, Claudivan F. de
.
Revista Brasileira de Engenharia Agrícola e Ambiental
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RESUMO Este trabalho teve como objetivo avaliar a influência da matéria orgânica no acúmulo de sais em três camadas de solo cultivado com plantas de noni irrigadas com água salobra, em condições de campo aberto e sombreamento parcial. O delineamento experimental foi em blocos ao acaso, disposto no esquema de parcelas subsubdivididas com cinco repetições. As parcelas foram constituídas pelos ambientes de cultivo (campo aberto e telado), as subparcelas pelas condutividades elétricas da água de irrigação (0,3; 1,5; 3,0; 4,5 e 6,0 dS m-1) e as subsubparcelas pela ausência e presença de matéria orgânica. Aos 110 dias após aplicação dos tratamentos, foram determinados a condutividade elétrica do extrato de saturação do solo e as concentrações de potássio, sódio, cálcio e magnésio em três camadas do solo (0-10, 10-20 e 20-30 cm). O sombreamento parcial reduziu o acúmulo total de sais e sódio no solo em relação ao campo aberto. O aumento da condutividade elétrica da água de irrigação reduziu as concentrações de potássio no solo, mas esse efeito foi compensado pela adição de matéria orgânica, que libera potássio, cálcio e magnésio para a nutrição das plantas. No entanto, o esterco bovino provoca acúmulo de sódio no solo nos tratamentos com maior salinidade da água.
ABSTRACT This study aimed to evaluate the influence of organic matter on the salt accumulation in three layers of soil cultivated with noni plants irrigated with brackish water, in open field and under partial shading conditions. The experimental design was in randomized blocks, arranged in a split-split-plot scheme with five replicates. The plots were constituted by the cultivation environments (open and shaded field), the subplots by the electrical conductivity of the irrigation water (0.3, 1.5, 3.0, 4.5, and 6.0 dS m-1), and the sub-subplots by the absence and presence of organic matter. At 110 days after application of the treatments, the electrical conductivity of the saturation extract and the potassium, sodium, calcium, and magnesium concentrations were determined in three soil layers (0-10, 10-20, and 20-30 cm). Partial shading reduced the total accumulation of salts and sodium in the soil compared to the open field. Increasing the electrical conductivity of irrigation water reduced potassium concentrations in the soil, but this effect is offset by the addition of organic matter, which releases potassium, calcium, and magnesium for plant nutrition. However, cattle manure increases sodium accumulation in the soil in treatments with the highest water salinity.
14.
Valorization of Hesperidin from Citrus Residues: Evaluation of Microwave-Assisted Synthesis of Hesperidin-Mg Complex and Their Insecticidal Activity
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Silva, Danielle F. da
; Bomfim, João P. A.
; Marchi, Rafael C.
; Amaral, Jéssica C.
; Pinto, Luciano S.
; Carlos, Rose M.
; Ferreira, Antonio G.
; Forim, Moacir R.
; Fernandes, João B.
; Silva, Maria F. G. F. da
; Oliveira, Regiane C. de
; Buss, David
; Kirk, William D. J.
; Bruce, Toby J. A.
.
The aim of the current study was the valorization of hesperidin, the dominant flavonoid in citrus processing waste, by microwave-assisted synthesis of hesperidin-Mg complex, improving its antioxidant activity and insecticidal potential. Here we show, for the first time, that microwave-assisted synthesis of [Mg(hesp)2(phen)]OAc (1) (hesp: hesperidin, phen: phenanthroline) improve the reaction rate and yield. The nuclear magnetic resonance (NMR) experiments proved to be powerful tools for the identification of three isomers in metal complexes. Moreover, we explore the insecticidal potential of 1 and [Mg(phen)2(Isov)]OAc (2) (Isov : isovanillic acid) complexes against three insects. Complex 1 killed 80% of adults whitefly at 0.14 μmol L-1, and 2 76% at 0.36 μmol L-1. There was a total mortality of Spodoptera frugiperda with 2 at 0.39 μmol L-1, and 83% with 1 at 0.14 μmol L-1. Both have similar activity, and represent a novel group of insecticide for Bemisia tabaci and S. frugiperda; nevertheless, the benefits of both as Myzus persicae repellent require further evaluation.
15.
COVID-19 in the Perioperative Period of Cardiovascular Surgery: the Brazilian Experience
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Gomes, Walter J.
; Rocco, Isadora
; Pimentel, Wallace S.
; Pinheiro, Aislan H. B.
; Souza, Paulo M. S.
; Costa, Luiz A. A.
; Teixeira, Marjory M. P.
; Ohashi, Leonardo P.
; Bublitz, Caroline
; Begot, Isis
; Moreira, Rita Simone L
; Hossne Jr, Nelson A.
; Vargas, Guilherme F.
; Branco, João Nelson R.
; Teles, Carlos A.
; Medeiros, Eduardo A. S.
; Sáfadi, Camila
; Rampinelli, Amândio
; Moratelli Neto, Leopoldo
; Rosado, Anderson Rosa
; Mesacasa, Franciele Kuhn
; Capriata, Ismael Escobar
; Segalote, Rodrigo Coelho
; Palmieri, Deborah Louize da Rocha Vianna
; Jardim, Amanda Cristina Mendes
; Vianna, Diego Sarty
; Coutinho, Joaquim Henrique de Souza Aguiar
; Jazbik, João Carlos
; Coutinho, Henrique Madureira da Rocha
; Kikuta, Gustavo
; Almeida, Zely Sant'Anna Marotti de
; Feguri, Gibran Roder
; Lima, Paulo Ruiz Lucio de
; Franco, Anna Carolina
; Borges, Danilo de Cerqueira
; Cruz, Felipe Ramos Honorato De La
; Croti, Ulisses Alexandre
; Borim, Bruna Cury
; Marchi, Carlos Henrique De
; Goraieb, Lilian
; Postigo, Karolyne Barroca Sanches
; Jucá, Fabiano Gonçalves
; Oliveira, Fátima Rosane de Almeida
; Souza, Rafael Bezerra de
; Zilli, Alexandre Cabral
; Mas, Raul Gaston Sanchez
; Bettiati Junior, Luiz Carlos
; Tranchesi, Ricardo
; Bertini Jr, Ayrton
; Franco, Leandro Vieira
; Fernandes, Priscila
; Oliveira, Fabiana
; Moraes Jr, Roberto
; Araújo, Thiago Cavalcanti Vila Nova de
; Braga, Otávio Penna
; Pedrosa Sobrinho, Antônio Cavalcanti
; Teixeira, Roberta Tavares Barreto
; Camboim, Irla Lavor Lucena
; Gomes, Eduardo Nascimento
; Reis, Pedro Horigushi
; Garcia, Luara Piovan
; Scorsioni, Nelson Henrique Goes
; Lago, Roberto
; Guizilini, Solange
.
Brazilian Journal of Cardiovascular Surgery
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Abstract Introduction: We investigated the clinical course and outcomes of patients submitted to cardiovascular surgery in Brazil and who had developed symptoms/signs of coronavirus disease 2019 (COVID-19) in the perioperative period. Methods: A retrospective multicenter study including 104 patients who were allocated in three groups according to time of positive real time reverse transcriptase-polymerase chain reaction (RT-PCR) for the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2): group 1, patients who underwent cardiac surgery > 10 days after positive RT-PCR; group 2, patients with a positive RT-PCR within 10 days before or after surgery; group 3, patients who presented positive RT-PCR > 10 days after surgery. The primary outcome was mortality and secondary outcomes were postoperative complications, intensive care unit (ICU) length of stay, and postoperative days of hospitalization. Results: The three groups were similar with respect to age, the European System of Cardiac Operative Risk Evaluation score, and comorbidities, except hypertension. Postoperative complications and death were significantly higher in groups 2 and 3 than in group 1, and no significant difference between groups 2 and 3 was seen. Group 2 showed a high prevalence of surgery performed as an urgent procedure. Although no significant differences were observed in ICU length of stay, total postoperative hospitalization time was significantly higher in group 3 than in groups 1 and 2. Conclusion: COVID-19 affecting the postoperative period of patients who underwent cardiovascular surgery is associated with a higher rate of morbidity and mortality. Delaying procedures in RT-PCR-positive patients may help reduce risks of perioperative complications and death.
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