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RESUMO A doença renal crônica (DRC) representa um dos principais problemas de saúde pública da atualidade. A dosagem da creatinina sérica e a estimativa da taxa de filtração glomerular (TFG) são as principais ferramentas para avaliação da função renal. Para a estimativa da TFG, existem diversas equações, sendo a mais recomendada a CKD-EPI (Chronic Kidney Disease – Epidemiology). Existem ainda algumas controvérsias com relação à dosagem da creatinina sérica e da estimativa da TFG, uma vez que vários fatores podem interferir nesse processo. Uma importante mudança recente foi a retirada da correção por raça das equações para estimativa da TFG, que superestimavam a função renal, e consequentemente retardavam a implementação de tratamentos como diálise e transplante renal. Neste documento de consenso da Sociedade Brasileira de Nefrologia e Sociedade Brasileira de Patologia Clínica e Medicina Laboratorial são revisados os principais conceitos relacionados à avaliação da função renal, possíveis controvérsias existentes e recomendações para a estimativa da TFG na prática clínica. DRC (DRC atualidade (TFG CKDEPI CKD EPI Chronic Epidemiology. Epidemiology . Epidemiology) processo clínica

ABSTRACT Chronic kidney disease (CKD) represents one of today’s main public health problems. Serum creatinine measurement and estimation of the glomerular filtration rate (GFR) are the main tools for evaluating renal function. There are several equations to estimate GFR, and CKD-EPI equation (Chronic Kidney Disease – Epidemiology) is the most recommended one. There are still some controversies regarding serum creatinine measurement and GFR estimation, since several factors can interfere in this process. An important recent change was the removal of the correction for race from the equations for estimating GFR, which overestimated kidney function, and consequently delayed the implementation of treatments such as dialysis and kidney transplantation. In this consensus document from the Brazilian Societies of Nephrology and Clinical Pathology and Laboratory Medicine, the main concepts related to the assessment of renal function are reviewed, as well as possible existing controversies and recommendations for estimating GFR in clinical practice. CKD (CKD todays today s problems (GFR CKDEPI EPI Epidemiology process transplantation Medicine reviewed practice

https://doi.org/10.1590/2175-8239-jbn-2023-0193en

[SciELO Preprints] - Demographic Profile and Characteristics of Adolescent and Pre-Adolescent Mothers During the COVID-19 Pandemic in the State of Ceará (Brazil)
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Azevedo, Evellyn Moreira de Silva, Nicolas Braga da Alves Santos, João Victor Matias, Ruan Oliveira Rodrigues, Micael da Silva Geraldo, Raul Rodrigues Mesquita de Lima, Riquelme Gabriel Santos, Gustavo Pires dos Oliveira Macedo, Pedro Nicolas Cândido Sobrinho, Silvio Alencar

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Publication date: 2024-08-23

Abstract: Pt Es En

A gravidez na adolescência é um problema significativo de saúde pública no Brasil, contribuindo para altas taxas de morbimortalidade entre mulheres jovens. Durante a gestação, muitas adolescentes abandonam a escola e o trabalho, o que resulta em menor qualificação e maior vulnerabilidade ao mercado de trabalho informal. Além disso, as adolescentes grávidas enfrentam riscos elevados de complicações gestacionais e desafios emocionais, como ansiedade e depressão. A pandemia exacerbou essas vulnerabilidades, especialmente em relação ao abuso doméstico, devido ao isolamento social. Este estudo justifica-se pela necessidade de compreender o perfil demográfico e as características das parturientes adolescentes no Ceará entre 2020 e 2022, oferecendo subsídios para políticas públicas que visem melhorar a qualidade de vida dessas jovens e de seus filhos. Todos os dados foram analisados utilizando R. Durante o período analisado, foram registrados 331.924 nascimentos vivos no Ceará, dos quais 21.667 (6,53%) eram de mães com idade igual ou inferior a 17 anos. A idade média das mães adolescentes foi de 15,93 ± 1,11 anos, enquanto a média para as mães adultas foi de 28,00 ± 6,21 anos, evidenciando uma diferença estatisticamente significativa (Teste-t de Student, P < 0,05). A análise também revelou uma diferença significativa entre a idade dos pais de crianças nascidas de mães adolescentes (22,25 ± 5,72 anos) em comparação à idade dos pais de crianças nascidas de mães adultas (32,45 ± 7,81 anos) (Figura 3, Teste-T, P < 0,05). No que se refere à etnia, adolescentes indígenas representaram 9,95% dos casos de gravidez, seguidas pelas adolescentes pardas (7,26%) e pretas (5,9%). A menor proporção foi observada entre adolescentes brancas (4,43%). Não houve diferença estatisticamente significativa entre os grupos indígenas, pardas, pretas e a população amarela. Quanto ao estado civil, 71% das adolescentes se declararam solteiras. A análise educacional demonstrou uma tendência significativa de gravidez entre adolescentes com Ensino Fundamental II incompleto, completo, ou Ensino Médio incompleto, indicando que essas jovens ainda estavam em fase de conclusão desses ciclos escolares. Não foi observada uma relação significativa entre a redução da idade materna e a diminuição do escore APGAR em recém-nascidos (APGAR = 0,014 × “IDADE DA MÃE” + 8,5; P < 0,05, R² = 0,0004). Além disso, não houve diferença significativa na proporção de anomalias congênitas entre os nascimentos de mães adolescentes e adultas.

El embarazo en la adolescencia es un problema significativo de salud pública en Brasil, que contribuye a altas tasas de morbimortalidad entre las mujeres jóvenes. Durante el embarazo, muchas adolescentes abandonan la escuela y el trabajo, lo que resulta en menor calificación y mayor vulnerabilidad en el mercado laboral informal. Además, las adolescentes embarazadas enfrentan mayores riesgos de complicaciones gestacionales y desafíos emocionales, como ansiedad y depresión. La pandemia exacerbó estas vulnerabilidades, especialmente en relación con el abuso doméstico, debido al aislamiento social. Este estudio se justifica por la necesidad de comprender el perfil demográfico y las características de las madres adolescentes en Ceará entre 2020 y 2022, ofreciendo apoyo para políticas públicas que busquen mejorar la calidad de vida de estas jóvenes y sus hijos. Todos los datos fueron analizados utilizando R. Durante el período analizado, se registraron 331.924 nacimientos vivos en Ceará, de los cuales 21.667 (6,53%) eran de madres de 17 años o menos. La edad promedio de las madres adolescentes fue de 15,93 ± 1,11 años, mientras que la media para las madres adultas fue de 28,00 ± 6,21 años, evidenciando una diferencia estadísticamente significativa (Prueba t de Student, P < 0,05). El análisis también reveló una diferencia significativa entre la edad de los padres de niños nacidos de madres adolescentes (22,25 ± 5,72 años) en comparación con la edad de los padres de niños nacidos de madres adultas (32,45 ± 7,81 años) (Prueba de Wilcoxon, P < 0,05). En cuanto a la etnia, las adolescentes indígenas representaron el 9,95% de los casos de embarazo, seguidas por las adolescentes mestizas (7,26%) y negras (5,9%). La menor proporción se observó entre las adolescentes blancas (4,43%). No hubo diferencia estadísticamente significativa entre los grupos indígenas, mestizas, negras y la población amarilla. En cuanto al estado civil, el 71% de las adolescentes se declararon solteras. El análisis educativo demostró una tendencia significativa de embarazo entre adolescentes con secundaria incompleta o completa, o educación media incompleta, lo que indica que estas jóvenes aún estaban en proceso de completar estos niveles educativos. No se observó una relación significativa entre la disminución de la edad materna y la reducción de la puntuación APGAR en los recién nacidos (APGAR = 0,014 × "EDAD DE LA MADRE" + 8,5; P < 0,05, R² = 0,0004). Además, no hubo diferencia significativa en la proporción de anomalías congénitas entre los nacimientos de madres adolescentes y adultas.

Adolescent pregnancy is a significant public health issue in Brazil, contributing to high morbidity and mortality rates among young women. During pregnancy, many adolescents drop out of school and work, leading to lower qualifications and increased vulnerability to the informal labor market. Moreover, pregnant adolescents face higher risks of gestational complications and emotional challenges, such as anxiety and depression. The pandemic exacerbated these vulnerabilities, particularly concerning domestic abuse, due to social isolation. This study is justified by the need to understand the demographic profile and characteristics of adolescent mothers in Ceará between 2020 and 2022, providing support for public policies aimed at improving the quality of life for these young women and their children. All data were analyzed using R. During the analyzed period, 331,924 live births were recorded in Ceará, of which 21,667 (6.53%) were from mothers aged 17 years or younger. The average age of adolescent mothers was 15.93 ± 1.11 years, while the average for adult mothers was 28.00 ± 6.21 years, showing a statistically significant difference (Student's t-test, P < 0.05). The analysis also revealed a significant difference between the age of fathers of children born to adolescent mothers (22.25 ± 5.72 years) compared to the age of fathers of children born to adult mothers (32.45 ± 7.81 years) (Wicoxon test, P < 0.05). Regarding ethnicity, indigenous adolescents accounted for 9.95% of pregnancy cases, followed by brown (7.26%) and black (5.9%) adolescents. The lowest proportion was observed among white adolescents (4.43%). There was no statistically significant difference among indigenous, mixed-race, black, and yellow populations. Concerning marital status, 71% of adolescents declared themselves single. Educational analysis showed a significant trend of pregnancy among adolescents with incomplete or complete middle school or incomplete high school education, indicating that these young women were still in the process of completing these educational levels. There was no significant relationship between decreasing maternal age and a reduction in newborns' APGAR scores (APGAR = 0.014 × "MOTHER'S AGE" + 8.5; P < 0.05, R² = 0.0004). Additionally, there was no significant difference in the proportion of congenital anomalies between births of adolescent and adult mothers.

https://doi.org/10.1590/SciELOPreprints.9645

Circuito dos Cuidados Psicossociais: sistematização de intervenção na crise psíquica no atendimento pré-hospitalar móvel
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Cavalcante, Renata de Almeida

; Vaz, Samita Batista Vieira

; Vaz, Tiago Silva

; Oliveira, Gustavo Carvalho de

; Rocha, Dais Gonçalves

Interface - Comunicação, Saúde, Educação

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2024, Volume 28 elocation e230211

Abstract: En Pt Es | Text: En Pt Es | PDF: En | PDF: Pt | PDF: Es

An experience report that aims to present the systematization of care for the management of psychic crises developed by the SAMU-DF Mental Health Center. The methodology, based on the steps of the Maguerez’s Arch, allowed both the identification of professionals’ difficulties regarding psychic crises management and the construction of the system called “Psychosocial Care Circuit’’ to guide the assistance of the mobile pre-hospital care. The Circuit has as mnemonic AEIOU, and each letter corresponds to an element evaluated as necessary for the psychic crisis intervention. Therefore, it is possible to affirm that the permanent education in health enables the transformative action of professionals, in addition to transforming the reality in which they are inserted, and that the systematization has accelerated the consolidation of the necessary skills for psychic crises care.

Um relato de experiência que visa apresentar a sistematização de atendimento para o manejo de crises psíquicas desenvolvida pelo Núcleo de Saúde Mental do Samu-DF. A metodologia, fundamentada nos passos do arco de Maguerez, permitiu desde a identificação das dificuldades dos profissionais no manejo das crises psíquicas até a construção da sistematização denominada “Circuito de Cuidados Psicossociais” para orientar a assistência no serviço pré-hospitalar móvel. O circuito tem como mnemônico “AEIOU”, e cada letra corresponde a um elemento avaliado como necessário na intervenção de crise psíquica. Assim, é possível afirmar que a Educação Permanente em Saúde possibilita uma ação transformadora dos profissionais e da realidade na qual estão inseridos, e a sistematização tem acelerado a consolidação das habilidades necessárias ao atendimento das crises psíquicas.

Un relato de experiencia cuyo objetivo es presentar la sistematización de atención para el manejo de crisis psíquicas desarrollada por el Núcleo de Salud Mental del SAMU-DF. La metodología, fundamentada en los pasos del arco de Maguerez, permitió desde la identificación de las dificultades de los profesionales en el manejo de las crisis psíquicas hasta la construcción de la sistematización denominada “Circuito de Cuidados Psicosociales” para orientar la asistencia en el servicio pre-hospitalario móvil. El circuito tiene como iniciales mnemónicas “AEIOU” y cada letra corresponde a un elemento evaluado como necesario en la intervención de crisis psíquica. De tal forma, es posible afirmar que la educación permanente en salud posibilita una acción transformadora de los profesionales y de la realidad en la cual están inseridos y que la sistematización ha acelerado la consolidación de las habilidades necesarias para la atención de las crisis psíquicas.

https://doi.org/10.1590/interface.230211

Brown spiders (Loxosceles) are taking hold in Pernambuco, Brazil: a case series, 2018-2022
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Amorim, Maria Lucineide Porto

; Simão, Diógenes Gayo de Oliveira

; Albuquerque, João Paulo Vieira e Silva de

; Ramos, Beatriz Maria Tenório

; Nascimento, Gustavo José Lopes do

; Mello, Maria Júlia Gonçalves de

Epidemiologia e Serviços de Saúde

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2024, Volume 33 elocation e2023568

Abstract: Pt Es En | Text: Pt Es En | PDF: Pt | PDF: Es | PDF: En

RESUMO Objetivo Descrever os acidentes por picada de aranhas-marrons (gênero Loxosceles), notificados no Centro de Informação de Assistência Toxicológica de Pernambuco (CIATox-PE), Brasil, no período de 2018 a 2022. Métodos Estudo de série, sobre casos notificados no CIATox-PE. Resultados Foram incluídos 22 casos com mediana de idade de 35 anos e houve predomínio do sexo feminino (13); os casos ocorreram nas zonas rural e urbana (12 versus 10), durante a noite (10), e Petrolina foi o município com mais notificações (6); as picadas ocorreram, principalmente, nos membros inferiores (11) e superiores (9), quase exclusivamente dentro das residências (21); para 8 acidentados, não se prescreveu soroterapia específica por terem ultrapassado o tempo de efetividade. Conclusão Os casos de loxoscelismo ocorreram com maior frequência no sexo feminino, nas zonas rural e urbana indiferentemente, quase todos foram intradomiciliares e houve demora na procura por atendimento médico.

RESUMEN Objetivo Describir accidentes causados por arañas pardas (género Loxosceles) notificados por el Centro de Información de Asistencia Toxicológica de Pernambuco (CIATox-PE), Brasil, de enero de 2018 a diciembre de 2022. Métodos Reporte de 22 casos notificados de CIATox-PE. Resultados Casos con media de idade de 35 años, predominio femenino (13); los casos ocurrieron en área rural/urbana (12 versus 10), por la noche (10); Petrolina fue el municipio con más notificaciones (6); las picaduras fueron principalmente en los miembros inferiores (11) y superiores (9), casi exclusivamente en el interior de las viviendas (21); en 8 de los casos no se indicó sueroterapia específica por haber superado el tiempo de efecto. Conclusión Los casos de loxoscelismo ocurrieron con mayor frecuencia en el sexo femenino, en áreas rurales y urbanas, y principalmente en el hogar, con demoras en la búsqueda de atención médica.

ABSTRACT Objective To describe accidents involving brown spider (genus Loxosceles) bites notified by the Pernambuco Poison Information and Care Center (CIATox-PE), Brazil, from January 2018 to December 2022. Methods This was a case series study of brown spider bites notified by the CIATox-PE. Results The study included 22 cases with median age of 35 years, the majority being female (13); the cases occurred in rural and urban areas (12 versus 10), at night (10); Petrolina was the municipality with the highest number of notifications (6); spider bites occurred mainly in the lower (11) and upper (9) limbs, almost exclusively inside households (21); specific serum therapy was not indicated for 8 cases because the time for its effectiveness had already elapsed. Conclusion Loxoscelism cases occurred more frequently in females, in both rural and urban areas and mainly at home, with delays in seeking medical care.

https://doi.org/10.1590/s2237-96222024v33e2023568.en

Brown spiders (Loxosceles) are taking hold in Pernambuco, Brazil: a case series, 2018-2022 Loxosceles (Loxosceles Pernambuco Brazil series 20182022 2018 2022 2018-202 2018202 201 202 2018-20 201820 20 2018-2 20182 2 2018-
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Amorim, Maria Lucineide Porto

; Simão, Diógenes Gayo de Oliveira

; Albuquerque, João Paulo Vieira e Silva de

; Ramos, Beatriz Maria Tenório

; Nascimento, Gustavo José Lopes do

; Mello, Maria Júlia Gonçalves de

Epidemiologia e Serviços de Saúde

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2024, Volume 33 elocation e2023568

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/s2237-96222024v33e2023568.en

Prospective, randomized, controlled trial assessing the effects of a driving pressure–limiting strategy for patients with acute respiratory distress syndrome due to community-acquired pneumonia (STAMINA trial): protocol and statistical analysis plan Prospective randomized pressurelimiting pressure limiting communityacquired community acquired STAMINA trial)
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Maia, Israel Silva

; Medrado Jr, Fernando Azevedo

; Tramujas, Lucas

; Tomazini, Bruno Martins

; Oliveira, Júlia Souza

; Sady, Erica Regina Ribeiro

; Barbante, Letícia Galvão

; Nicola, Marina Lazzari

; Gurgel, Rodrigo Magalhães

; Damiani, Lucas Petri

; Negrelli, Karina Leal

; Miranda, Tamiris Abait

; Santucci, Eliana

; Valeis, Nanci

; Laranjeira, Ligia Nasi

; Westphal, Glauco Adrieno

; Fernandes, Ruthy Perotto

; Zandonai, Cássio Luis

; Pincelli, Mariangela Pimentel

; Figueiredo, Rodrigo Cruvinel

; Bustamante, Cíntia Loss Sartori

; Norbin, Luiz Fernando

; Boschi, Emerson

; Lessa, Rafael

; Romano, Marcelo Pereira

; Miura, Mieko Cláudia

; Alencar Filho, Meton Soares de

; Dantas, Vicente Cés de Souza

; Barreto, Priscilla Alves

; Hernandes, Mauro Esteves

; Grion, Cintia Magalhães Carvalho

; Laranjeira, Alexandre Sanches

; Mezzaroba, Ana Luiza

; Bahl, Marina

; Starke, Ana Carolina

; Biondi, Rodrigo Santos

; Dal-Pizzol, Felipe

; Caser, Eliana Bernadete

; Thompson, Marlus Muri

; Padial, Andrea Allegrini

; Veiga, Viviane Cordeiro

; Leite, Rodrigo Thot

; Araújo, Gustavo

; Guimarães, Mário

; Martins, Priscilla de Aquino

; Lacerda, Fábio Holanda

; Hoffmann Filho, Conrado Roberto

; Melro, Livia

; Pacheco, Eduardo

; Ospina-Táscon, Gustavo Adolfo

; Ferreira, Juliana Carvalho

; Freires, Fabricio Jocundo Calado

; Machado, Flávia Ribeiro

; Cavalcanti, Alexandre Biasi

; Zampieri, Fernando Godinho

Critical Care Science

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2024, Volume 36 elocation e20240210en

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Contexto: Em estudos observacionais sobre a síndrome do desconforto respiratório agudo, sugeriu-se que a driving pressure é o principal fator de lesão pulmonar induzida por ventilador e de mortalidade. Não está claro se uma estratégia de limitação da driving pressure pode melhorar os desfechos clínicos. Objetivo: Descrever o protocolo e o plano de análise estatística que serão usados para testar se uma estratégia de limitação da driving pressure envolvendo a titulação da pressão positiva expiratória final de acordo com a melhor complacência respiratória e a redução do volume corrente é superior a uma estratégia padrão envolvendo o uso da tabela de pressão positiva expiratória final baixa do protocolo ARDSNet, em termos de aumento do número de dias sem ventilador em pacientes com síndrome do desconforto respiratório agudo devido à pneumonia adquirida na comunidade. Métodos: O estudo STAMINA (ventilator STrAtegy for coMmunIty acquired pNeumoniA) é randomizado, multicêntrico e aberto e compara uma estratégia de limitação da driving pressure com a tabela de pressão positiva expiratória final baixa do protocolo ARDSnet em pacientes com síndrome do desconforto respiratório agudo moderada a grave devido à pneumonia adquirida na comunidade internados em unidades de terapia intensiva. Esperamos recrutar 500 pacientes de 20 unidades de terapia intensiva brasileiras e duas colombianas. Eles serão randomizados para um grupo da estratégia de limitação da driving pressure ou para um grupo de estratégia padrão usando a tabela de pressão positiva expiratória final baixa do protocolo ARDSnet. No grupo da estratégia de limitação da driving pressure, a pressão positiva expiratória final será titulada de acordo com a melhor complacência do sistema respiratório. Desfechos: O desfecho primário é o número de dias sem ventilador em 28 dias. Os desfechos secundários são a mortalidade hospitalar e na unidade de terapia intensiva e a necessidade de terapias de resgate, como suporte de vida extracorpóreo, manobras de recrutamento e óxido nítrico inalado. Conclusão: O STAMINA foi projetado para fornecer evidências sobre se uma estratégia de limitação da driving pressure é superior à estratégia da tabela de pressão positiva expiratória final baixa do protocolo ARDSnet para aumentar o número de dias sem ventilador em 28 dias em pacientes com síndrome do desconforto respiratório agudo moderada a grave. Aqui, descrevemos a justificativa, o desenho e o status do estudo. Contexto sugeriuse sugeriu clínicos Objetivo ARDSNet Métodos ventilator pNeumoniA randomizado 50 2 colombianas Desfechos resgate extracorpóreo inalado Conclusão Aqui justificativa 5

ABSTRACT Background: Driving pressure has been suggested to be the main driver of ventilator-induced lung injury and mortality in observational studies of acute respiratory distress syndrome. Whether a driving pressure-limiting strategy can improve clinical outcomes is unclear. Objective: To describe the protocol and statistical analysis plan that will be used to test whether a driving pressure-limiting strategy including positive end-expiratory pressure titration according to the best respiratory compliance and reduction in tidal volume is superior to a standard strategy involving the use of the ARDSNet low-positive end-expiratory pressure table in terms of increasing the number of ventilator-free days in patients with acute respiratory distress syndrome due to community-acquired pneumonia. Methods: The ventilator STrAtegy for coMmunIty acquired pNeumoniA (STAMINA) study is a randomized, multicenter, open-label trial that compares a driving pressure-limiting strategy to the ARDSnet low-positive end-expiratory pressure table in patients with moderate-to-severe acute respiratory distress syndrome due to community-acquired pneumonia admitted to intensive care units. We expect to recruit 500 patients from 20 Brazilian and 2 Colombian intensive care units. They will be randomized to a driving pressure-limiting strategy group or to a standard strategy using the ARDSNet low-positive end-expiratory pressure table. In the driving pressure-limiting strategy group, positive end-expiratory pressure will be titrated according to the best respiratory system compliance. Outcomes: The primary outcome is the number of ventilator-free days within 28 days. The secondary outcomes are in-hospital and intensive care unit mortality and the need for rescue therapies such as extracorporeal life support, recruitment maneuvers and inhaled nitric oxide. Conclusion: STAMINA is designed to provide evidence on whether a driving pressure-limiting strategy is superior to the ARDSNet low-positive end-expiratory pressure table strategy for increasing the number of ventilator-free days within 28 days in patients with moderate-to-severe acute respiratory distress syndrome. Here, we describe the rationale, design and status of the trial. Background ventilatorinduced induced pressurelimiting limiting unclear Objective endexpiratory end expiratory lowpositive low ventilatorfree free communityacquired community Methods (STAMINA multicenter openlabel open label moderatetosevere moderate severe units 50 Outcomes inhospital hospital support oxide Conclusion Here rationale 5

https://doi.org/10.62675/2965-2774.20240210-en

Assessment of sexual and body esteem in postpartum women with or without perineal laceration: a cross-sectional study with cultural translation and validation of the Vaginal Changes Sexual and Body Esteem Scale laceration crosssectional cross sectional
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de Souza, Renata Stefânia Olah

; Luz, Adriana Gomes

; Zielinski, Ruth

; Sarian, Luis Otavio Zanatta

; Juliato, Cassia Raquel Teatin

; Lara, Lucia Alves da Silva

; Brito, Luiz Gustavo Oliveira

Revista Brasileira de Ginecologia e Obstetrícia

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2024, Volume 46 elocation e-rbgo35

Abstract: En | Text: En | PDF: En

Objective: We aimed to translate and determine cultural validity of the Vaginal Changes Sexual and Body Esteem Scale (VSBE) for Brazilian Portuguese language in postpartum women who underwent vaginal delivery with or without perineal laceration and cesarean section. Methods: A cross-sectional study conducted virtually, with online data collection through a survey with 234 postpartum women of 975 that were invited. Clinical, sociodemographic, and psychometric variables from the VSBE questionnaire were analyzed (content validity index, internal consistency, test-retest reliability, construct/structural and discriminant validity). Multivariate analysis was performed to explore associated factors with the presence of perineal laceration. Results: One-hundred fifty-eight women experienced vaginal delivery, of which 24.79% had an intact perineum, 33.33% had perineal laceration, and 9.4% underwent episiotomy; and 76 participants had cesarean sections. Women with perineal laceration were older, presented dyspareunia and previous surgeries than women without perineal laceration (p<0.05). For VSBE, a high internal consistency (Cronbach's α > 0.7) was observed, but it did not correlate with Body Attractiveness Questionnaire and Female Sexual Function Index; however, it correlated with the presence of women sutured for perineal laceration. Moreover, VSBE presented good structural validity with two loading factors after exploratory factor analysis. VSBE also demonstrated discriminant validity between the presence or absence of perineal laceration. The presence of urinary incontinence (UI) (OR=2.716[1.015-4.667];p=0.046) and a higher VSBE total score (OR=1.056[1.037-1.075];p<0.001) were the only factors associated with perineal laceration. Conclusion: Vaginal Changes Sexual and Body Esteem Scale demonstrated appropriate translation and good internal consistency, discriminant/construct validity and reliability. Vaginal Changes Sexual and Body Esteem Scale total score and presence of UI were associated with women that underwent perineal laceration. Objective (VSBE section Methods crosssectional cross sectional virtually 23 97 invited Clinical sociodemographic content index testretest test retest reliability constructstructural construct validity. . validity) Results Onehundred One hundred fiftyeight fifty eight 2479 24 79 24.79 perineum 3333 33 33.33 94 9 4 9.4 episiotomy 7 sections older p<0.05. p005 p p<0.05 0 05 (p<0.05) Cronbachs Cronbach s 0.7 07 observed Index however Moreover (UI OR=2.7161.0154.667p=0.046 OR271610154667p0046 ORp OR=2.716 1.015 4.667 p=0.046 OR 2 716 1 015 667 046 (OR=2.716[1.015-4.667];p=0.046 OR=1.0561.0371.075p<0.001 OR105610371075p0001 OR=1.056 1.037 1.075 p<0.001 056 037 075 001 (OR=1.056[1.037-1.075];p<0.001 Conclusion discriminantconstruct 247 24.7 333 3 33.3 9. p00 p<0.0 (p<0.05 0. 7161 0154 667p OR=2.7161.0154.667p=0.04 OR271610154667p004 OR2716 OR=2.71 1015 1.01 4667 4.66 p0046 p=0.04 71 01 66 04 (OR=2.716[1.015-4.667];p=0.04 0561 0371 075p OR=1.0561.0371.075p<0.00 OR105610371075p000 OR1056 OR=1.05 1037 1.03 1075 1.07 p0001 p<0.00 03 00 (OR=1.056[1.037-1.075];p<0.00 24. 33. p0 p<0. (p<0.0 OR=2.7161.0154.667p=0.0 OR271610154667p00 OR271 OR=2.7 101 1.0 466 4.6 p004 p=0.0 6 (OR=2.716[1.015-4.667];p=0.0 OR=1.0561.0371.075p<0.0 OR105610371075p00 OR105 OR=1.0 103 107 p000 (OR=1.056[1.037-1.075];p<0.0 p<0 (p<0. OR=2.7161.0154.667p=0. OR271610154667p0 OR27 OR=2. 10 1. 46 4. p=0. (OR=2.716[1.015-4.667];p=0. OR=1.0561.0371.075p<0. OR105610371075p0 OR10 OR=1. (OR=1.056[1.037-1.075];p<0. p< (p<0 OR=2.7161.0154.667p=0 OR271610154667p OR2 OR=2 p=0 (OR=2.716[1.015-4.667];p=0 OR=1.0561.0371.075p<0 OR105610371075p OR1 OR=1 (OR=1.056[1.037-1.075];p<0 (p< OR=2.7161.0154.667p= OR= p= (OR=2.716[1.015-4.667];p= OR=1.0561.0371.075p< (OR=1.056[1.037-1.075];p< (p OR=2.7161.0154.667p (OR=2.716[1.015-4.667];p OR=1.0561.0371.075p (OR=1.056[1.037-1.075];p

https://doi.org/10.61622/rbgo/2024rbgo35

Terracing Reduces Arbuscular Mycorrhizal fungi Spore Loss through Surface Runoff
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Colozzi Filho, Arnaldo

; Bertagnoli, Breynner Gustavo Pavão

; Menoncin, Andréa Scaramal da Silva

; Oliveira, José Francirlei de

; Campana, Ingrid Oliva

; Machineski, Gabriela Silva

; Barbosa, Graziela Moraes de Cesare

Brazilian Archives of Biology and Technology

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2024, Volume 67 N. spe1 elocation e24230801

Abstract: En | Text: En | PDF: En

Abstract Surface runoff in agricultural areas promotes the transport of biological structures, such as arbuscular mycorrhizal fungi (AMF) spores, along with mineral particles, nutrients, and organic matter. Limited information exists regarding the relationships between the erosive process and the loss of AMF spores at the hillslope scale, as well as the effect of terracing on these relationships. The objective of this study was to quantify the loss of AMF spores in surface runoff water from agricultural soil managed under no-till and terraced conditions. The research was conducted in the Ribeirão Vermelho watershed, in a hillslope area in Cambé, Paraná, Brazil. Two experimental plots measuring 2.5 hectares each were installed, with one managed without terraces (NTP) and the other with level terraces (TP). At the lower end of the plots, a runoff flow measurement structure (H-channel) was installed to determine the flow rate and suspended spore count. The runoff duration, peak flow rate, and spore count were determined during the period from October 2019 to October 2022. The terrace reduced over 35% of suspended spore loss, and the hysteresis pattern showed a counterclockwise loop in NTP and a clockwise loop in TP for events with higher peak flow rates. The hysteresis pattern indicated rapid spore mobilization and transport in TP, suggesting that spores originated from more distant sources or required more energy for transportation in NTP. Overall, there is evidence that the terrace influences spore variability on the hillslope, reinforcing the need for terracing in agricultural hillslope areas. structures (AMF particles nutrients matter scale notill no till conditions watershed Cambé Paraná Brazil 25 2 5 2. (NTP TP. . (TP) Hchannel H channel (H-channel duration 201 2022 35 rates Overall (TP 20 202 3

https://doi.org/10.1590/1678-4324-pssm-2024230801

Saccadic movements during an exploratory visual search task in patients with glaucomatous visual field loss
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Oliveira, Mirella Almeida

; Senger, Cassia

; Souza, Raquel Pantojo

; Moraes, Carlos Gustavo de

; Messias, André

; Paula, Jayter Silva

Arquivos Brasileiros de Oftalmologia

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2024, Volume 87 N. 3 elocation e2022-0366

Abstract: En | Text: En | PDF: En

ABSTRACT Purpose: To evaluate the saccadic movements of patients with visual field loss due to primary open-angle glaucoma. Methods: Thirteen patients with good visual acuity (0.2 logMAR or better) (seven patients with primary open-angle glaucoma 65 ± 13 years) and six controls (51 ± 6 years) yielded a comprehensive ophthalmological examination, including Humphrey Visual Field tests (SITA-Standard 24-2), and performed a monocular, exploratory digital visual search task that quantifies the duration for finding the number “4” on a random array of digits distributed on the screen. After individual adjustments of the angle and distance positioning, the screen was spatially matched with the 24-2 visual field, and divided into five areas for analysis. During the task, saccades were simultaneously recorded in the same eye with a video-based eye tracker. Results: The patients with primary open-angle glaucoma showed a significantly higher number of saccades/screen (median ± interquartile range, 59.00 ± 29.00 vs. 32.50 ± 19.75 saccades (p=0.027) and visual search time per screen (38.50 ± 60.14 vs. 23.75 ± 8.90 seconds (p=0.035) than the controls did. Although the univariate analysis indicated a significant correlation with visual field mean deviation (coefficient=26.19 (p=0.02), only the visual search time/screen was significantly associated with the number of saccades/screen in the multivariate regression model (coefficient=0.55 (p<0.001). Overall, no significant correlation was observed between the sectorial number of saccades and the sensitivity of the five visual field areas. Conclusions: The patients with primary open-angle glaucoma show impaired search performance and showed a higher number of saccades needed to find stimuli when performing the exploratory visual task. Purpose openangle open Methods 0.2 02 0 2 (0. better seven 1 years 51 (5 examination SITAStandard SITA Standard 242, 242 24 , 24-2) monocular 4 “4 positioning 24- videobased video based tracker Results saccadesscreen median range 5900 59 00 59.0 2900 29 29.0 vs 3250 32 50 32.5 1975 19 75 19.7 p=0.027 p0027 p 027 (p=0.027 38.50 3850 38 (38.5 6014 60 14 60.1 2375 23 23.7 890 8 90 8.9 p=0.035 p0035 035 (p=0.035 did coefficient=26.19 coefficient2619 coefficient 26 (coefficient=26.1 p=0.02, p002 p=0.02 (p=0.02) timescreen coefficient=0.55 coefficient055 55 (coefficient=0.5 p<0.001. p0001 p<0.001 . 001 (p<0.001) Overall Conclusions 0. (0 5 ( “ 590 59. 290 29. 325 3 32. 197 7 19. (p=0.02 38.5 385 (38. 601 60. 237 23. 89 9 8. p=0.03 p003 03 (p=0.03 coefficient=26.1 coefficient261 (coefficient=26. p00 p=0.0 coefficient=0.5 coefficient05 (coefficient=0. p000 p<0.00 (p<0.001 (p=0.0 38. (38 coefficient=26. coefficient26 (coefficient=26 p0 p=0. coefficient=0. coefficient0 (coefficient=0 p<0.0 (p<0.00 (p=0. (3 coefficient=26 coefficient2 (coefficient=2 p=0 coefficient=0 (coefficient= p<0. (p<0.0 (p=0 coefficient=2 p= coefficient= (coefficient p<0 (p<0. (p= p< (p<0 (p (p<

https://doi.org/10.5935/0004-2749.2022-0366

10.

HOSPITALIZATION, USE OF BIOLOGICS AND SURGERY RATES IN INFLAMMATORY BOWEL DISEASES: A SINGLE-CENTRE COMPARATIVE ANALYSIS BETWEEN PUBLIC AND PRIVATE HEALTHCARE SYSTEMS IN A TERTIARY UNIT FROM LATIN AMERICA HOSPITALIZATION DISEASES SINGLECENTRE SINGLE CENTRE
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ZACHARIAS, Patrícia

; MAGRO, Daniéla Oliveira

; PERUSSOLO, Milena

; BARAÚNA, Fernanda da Silva Barbosa

; KOTZE, Paulo Gustavo

Arquivos de Gastroenterologia

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2024, Volume 61 elocation e23140

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Contexto: As doenças inflamatórias intestinais (DII) têm taxas crescentes de incidência e prevalência em todo o mundo. Na DII, são escassos os estudos comparando as diferenças entre os pacientes de acordo com o nível socioeconômico. Objetivo: Nosso objetivo foi avaliar comparativamente as hospitalizações, o uso de biológicos e as taxas de cirurgia em pacientes com DII entre os sistemas público e privado de saúde. Métodos: Estudo de coorte retrospectivo unicêntrico em pacientes com DII de uma unidade terciária de referência da América Latina, entre 2015 e 2021. Os pacientes com DC (doença de Crohn) e retocolite ulcerativa foram classificados em dois subgrupos: sistema público e privado. Características demográficas, hospitalizações, necessidade de cirurgia e biológicos foram comparadas. Resultados: Foram inclusos 500 pacientes, sendo 322 com DC e 178 com retocolite ulcerativa. Internações por DC foram frequentes em ambos os sistemas de saúde (76,28% na rede privada e 67,46% na rede pública). Mais da metade dos pacientes havia sido submetida a uma ou mais cirurgias abdominais relacionadas à DC, sem diferença significativa entre os subgrupos. Embora não tenha havido diferença nas taxas de uso de terapia biológica nos subgrupos de DC, o infliximabe foi mais utilizado no ambiente público (57,69% vs 43,97%). Não houve diferença nas internações relacionadas a retocolite ulcerativa entre os subgrupos (público 30,69% e privado 37,66%) e nas taxas de colectomia (público: 16,83%, privado: 19,48%). Os biológicos foram prescritos quase duas vezes mais no privado do que no público (45,45 vs 22,77%). Conclusão: Não houve diferença nas taxas de internação hospitalar e de cirurgia abdominal entre os sistemas. Nos pacientes com retocolite ulcerativa, houve maior utilização da terapia biológica no setor privado de saúde. Contexto (DII mundo socioeconômico Objetivo hospitalizações Métodos Latina 201 2021 doença Crohn demográficas comparadas Resultados 50 32 17 76,28% 7628 76 28 (76,28 6746 67 46 67,46 pública. pública . pública) 57,69% 5769 57 69 (57,69 43,97%. 4397 43,97% 43 97 43,97%) 3069 30 30,69 37,66% 3766 37 66 1683 16 83 16,83% 19,48%. 1948 19,48% 19 48 19,48%) 45,45 4545 45 (45,4 22,77%. 2277 22,77% 22 77 22,77%) Conclusão 20 202 5 3 1 76,28 762 7 2 (76,2 674 6 4 67,4 57,69 576 (57,6 439 43,97 9 306 30,6 37,66 376 168 8 16,83 194 19,48 45,4 454 (45, 227 22,77 76,2 (76, 67, 57,6 (57, 43,9 30, 37,6 16,8 19,4 45, (45 22,7 76, (76 57, (57 43, 37, 16, 19, (4 22, (7 (5 (

ABSTRACT Background: Inflammatory bowel diseases (IBD) have rising incidence and prevalence rates globally. In IBD, there are scarce studies comparing differences between patients according to socioeconomic status. Our aim was to comparatively evaluate hospitalizations, use of biologics and rates of surgery in patients with IBD between public and private healthcare systems. Methods: Single-center retrospective cohort study in patients with IBD from a tertiary referral unit from Latin America, between 2015 and 2021. CD and UC patients were classified into two subgroups: public and private systems. Demographic characteristics, hospitalizations, need for surgery and biologics were compared. Results: A total of 500 patients were included, 322 with CD and 178 with UC. CD-related hospitalizations were frequently observed in both healthcare systems (76.28% in private and 67.46% in public). More than half of the patients had been submitted to one or more CD-related abdominal surgery, with no significant difference between the subgroups. Although there was no difference in the rates of use of biological therapy in CD subgroups, infliximab was more used in the public setting (57.69% vs 43.97%). There was no difference in UC-related hospitalizations between the subgroups (public 30.69% and private 37.66%) as well as the rates of colectomy (public: 16.83%, private: 19.48%). Biologics were prescribed almost twice as often in private as compared to public (45.45 vs 22.77%). Conclusion: There were no differences in the rates of hospitalization and abdominal surgery between the systems. In patients with UC, there was greater use of biological therapy in the private healthcare setting. Background (IBD globally status Methods Singlecenter Single center America 201 2021 characteristics Results 50 included 32 17 CDrelated related 76.28% 7628 76 28 (76.28 6746 67 46 67.46 public. . public) 57.69% 5769 57 69 (57.69 43.97%. 4397 43.97% 43 97 43.97%) UCrelated 3069 30 30.69 37.66% 3766 37 66 1683 16 83 16.83% 19.48%. 1948 19.48% 19 48 19.48%) 45.45 4545 45 (45.4 22.77%. 2277 22.77% 22 77 22.77%) Conclusion 20 202 5 3 1 76.28 762 7 2 (76.2 674 6 4 67.4 57.69 576 (57.6 439 43.97 9 306 30.6 37.66 376 168 8 16.83 194 19.48 45.4 454 (45. 227 22.77 76.2 (76. 67. 57.6 (57. 43.9 30. 37.6 16.8 19.4 45. (45 22.7 76. (76 57. (57 43. 37. 16. 19. (4 22. (7 (5 (

https://doi.org/10.1590/s0004-2803.24612023-140

11.

Aprendendo a construir explicações científicas: uma análise do cotidiano da sala de aula de ciências científicas
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Carneiro, Thalita de Oliveira

; Franco, Luiz Gustavo

; Teles, Ana Paula Souto Silva

; Matos, Santer Alvares de

Revista Brasileira de Educação

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2024, Volume 29 elocation e290025

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Esta pesquisa analisa como estudantes de uma turma do oitavo ano do Ensino Fundamental propuseram e revisaram explicações para um fenômeno em aulas de ciências. Orientados pela Etnografia em Educação, construímos dados com base em observações do cotidiano dessa turma e analisamos conexões entre textos, contextos e eventos. Os resultados indicam o papel do professor sobre o caráter provisório e incerto conferido às explicações científicas; o uso de discussões - ora em grupo, ora com toda a turma - como recurso por meio do qual os estudantes validaram (ou não) suas explicações; além das interpretações dadas pelos estudantes às relações entre dados e explicações em construção. Esses recursos deram forma às práticas de propor/revisar explicações, o que foi evidenciado por mudanças nas propostas explicativas ao longo dos eventos. O estudo oferece contribuições à área de pesquisa de Educação em Ciências e implicações para a prática pedagógica. ciências textos eventos científicas grupo ou não construção proporrevisar propor revisar pedagógica

ABSTRACT This paper analyzes how 8th graders proposed and revised explanations for a phenomenon in Science lessons. Guided by Ethnography in Education, we gathered data from observations of the daily life of these lessons and analyzed connections between texts, contexts and events. The results indicate the teacher’s role on the provisional and uncertain character given to scientific explanations; the use of discussions - sometimes in groups, sometimes with the whole class - as a resource through which students validated (or not) their explanations; and the interpretations given by students to the relationships between data and explanations under construction. These resources shaped the practices of proposing/reviewing explanations, which were evidenced by changes in explanatory proposals throughout events. The study offers contributions to the research area of Science Education and implications for pedagogical practice. th texts events teachers teacher s groups or not construction proposingreviewing proposing reviewing practice

RESUMEN Esta investigación analiza cómo los estudiantes de una clase de la escuela secundaria de octavo grado propusieron y revisaron explicaciones para un fenómeno en ciencias. Guiados por Etnografía en la educación, construyeron datos a partir de observaciones de la vida diaria de esta clase y analizaron las conexiones entre textos, contextos y eventos. Los resultados indicaron el rol del docente sobre el carácter provisional e incierto que se le da a las explicaciones científicas; el uso de discusiones - a veces en equipos, a veces con toda la clase - como recurso a través del cual los estudiantes validaron (o no) sus explicaciones; y las interpretaciones dadas por los estudiantes a las relaciones entre datos y explicaciones en construcción. Estos recursos dieron forma a las prácticas de proponer/revisar explicaciones, lo que se evidenció mediante cambios en las propuestas explicativas a lo largo de los eventos. El estudio ofrece contribuciones al área de investigación de la Educación Científica e implicaciones para la práctica pedagógica. ciencias educación textos eventos científicas equipos o no construcción proponerrevisar proponer revisar pedagógica

https://doi.org/10.1590/s1413-24782024290025

12.

Lung cancer screening in Brazil: recommendations from the Brazilian Society of Thoracic Surgery, Brazilian Thoracic Association, and Brazilian College of Radiology and Diagnostic Imaging Brazil Surgery Association
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Pereira, Luiz Fernando Ferreira

; Santos, Ricardo Sales dos

; Bonomi, Daniel Oliveira

; Franceschini, Juliana

; Santoro, Ilka Lopes

; Miotto, André

; Sousa, Thiago Lins Fagundes de

; Chate, Rodrigo Caruso

; Hochhegger, Bruno

; Gomes Neto, Artur

; Schneider, Airton

; Araújo Neto, César Augusto de

; Escuissato, Dante Luiz

; Prado, Gustavo Faibischew

; Costa-Silva, Luciana

; Zamboni, Mauro Musa

; Ghefter, Mario Claudio

; Corrêa, Paulo César Rodrigues Pinto

; Torres, Pedro Paulo Teixeira e Silva

; Mussi, Ricardo Kalaf

; Muglia, Valdair Francisco

; Godoy, Irma de

; Bernardo, Wanderley Marques

Jornal Brasileiro de Pneumologia

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2024, Volume 50 N. 1 elocation e20230233

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O câncer de pulmão (CP) é uma das neoplasias mais comuns e letais no Brasil, e apenas 15% dos pacientes são diagnosticados nos estágios iniciais. O tabagismo persiste como o responsável por mais de 85% de todos os casos. O rastreamento do CP (RCP) por meio da TC de baixa dosagem de radiação (TCBD) reduz a mortalidade do CP em 20%, e, quando combinado com a cessação do tabagismo, essa redução chega a 38%. Na última década, diversos países adotaram o RCP como recomendação de saúde populacional. No Brasil, embora ainda incipiente, a discussão sobre o tema é cada vez mais ampla e necessária. Com o intuito de aumentar o conhecimento e estimular o debate sobre o RCP, a Sociedade Brasileira de Cirurgia Torácica, a Sociedade Brasileira de Pneumologia e Tisiologia e o Colégio Brasileiro de Radiologia e Diagnóstico por Imagem constituíram um painel de especialistas para elaborar as recomendações para o RCP. As recomendações aqui apresentadas foram baseadas em revisão narrativa da literatura, com ênfase em grandes estudos populacionais, em revisões sistemáticas e em recomendações de diretrizes internacionais, sendo construídas após ampla discussão pelo grupo de especialistas. Os temas revisados foram os seguintes: porque rastrear, considerações gerais sobre tabagismo, epidemiologia do CP, critérios de elegibilidade, achados incidentais, lesões granulomatosas, modelos probabilísticos, requisitos mínimos da TCBD, aquisições volumétricas, riscos do rastreamento, estrutura mínima e papel da equipe multidisciplinar, conduta segundo o Lung CT Screening Reporting and Data System (Lung-RADS), custos vs. benefícios e perspectivas do rastreamento. (CP Brasil 15 iniciais 85 casos (RCP TCBD (TCBD 20 20% 38 38% década populacional incipiente necessária Torácica literatura populacionais internacionais seguintes rastrear elegibilidade incidentais granulomatosas probabilísticos volumétricas multidisciplinar LungRADS, LungRADS RADS , (Lung-RADS) vs 1 8 2 3 (Lung-RADS

ABSTRACT Although lung cancer (LC) is one of the most common and lethal tumors, only 15% of patients are diagnosed at an early stage. Smoking is still responsible for more than 85% of cases. Lung cancer screening (LCS) with low-dose CT (LDCT) reduces LC-related mortality by 20%, and that reduction reaches 38% when LCS by LDCT is combined with smoking cessation. In the last decade, a number of countries have adopted population-based LCS as a public health recommendation. Albeit still incipient, discussion on this topic in Brazil is becoming increasingly broad and necessary. With the aim of increasing knowledge and stimulating debate on LCS, the Brazilian Society of Thoracic Surgery, the Brazilian Thoracic Association, and the Brazilian College of Radiology and Diagnostic Imaging convened a panel of experts to prepare recommendations for LCS in Brazil. The recommendations presented here were based on a narrative review of the literature, with an emphasis on large population-based studies, systematic reviews, and the recommendations of international guidelines, and were developed after extensive discussion by the panel of experts. The following topics were reviewed: reasons for screening; general considerations about smoking; epidemiology of LC; eligibility criteria; incidental findings; granulomatous lesions; probabilistic models; minimum requirements for LDCT; volumetric acquisition; risks of screening; minimum structure and role of the multidisciplinary team; practice according to the Lung CT Screening Reporting and Data System; costs versus benefits of screening; and future perspectives for LCS. LC (LC tumors 15 stage 85 cases (LCS lowdose low dose (LDCT LCrelated related 20 20% 38 cessation decade populationbased population recommendation incipient necessary Surgery Association literature studies reviews guidelines reviewed criteria findings lesions models acquisition team System 1 8 2 3

https://doi.org/10.36416/1806-3756/e20230233

13.

Circuito dos Cuidados Psicossociais: sistematização de intervenção na crise psíquica no atendimento pré-hospitalar móvel Psicossociais préhospitalar pré hospitalar
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Cavalcante, Renata de Almeida

; Vaz, Samita Batista Vieira

; Vaz, Tiago Silva

; Oliveira, Gustavo Carvalho de

; Rocha, Dais Gonçalves

Interface - Comunicação, Saúde, Educação

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2024, Volume 28 elocation e230211

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/interface.230211

14.

SARS-CoV-2 shedding, infectivity, and evolution in an immunocompromised adult patient SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- shedding infectivity SARS-CoV
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Mendes-Correa, Maria Cassia

; Ghilardi, Fábio de Rose

; Salomão, Matias Chiarastelli

; Villas-Boas, Lucy Santos

; Paula, Anderson Vicente de

; Paiao, Heuder Gustavo Oliveira

; Costa, Antonio Charlys da

; Tozetto-Mendoza, Tânia Regina

; Freire, Wilton

; Sales, Flavia Cristina Silva

; Claro, Ingra Morales

; Sabino, Ester Cerdeira

; Faria, Nuno Rodrigues

; Witkin, Steven Sol

Revista do Instituto de Medicina Tropical de São Paulo

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2024, Volume 66 elocation e28

Abstract: En | Text: En | PDF: En

ABSTRACT This study aimed to provide further insight into the evolutionary dynamics of SARS-CoV-2 by analyzing the case of a 40-year-old man who had previously undergone autologous hematopoietic stem cell transplantation due to a diffuse large B-cell lymphoma. He developed a persistent SARS-CoV-2 infection lasting at least 218 days and did not manifest a humoral immune response to the virus during this follow-up period. Whole-genome sequencing and viral cultures confirmed a persistent infection with a replication-positive virus that had undergone genetic variation for at least 196 days after symptom onset. SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- 40yearold yearold 40 year old Bcell B lymphoma 21 followup follow up period Wholegenome Whole genome replicationpositive replication positive 19 onset SARS-CoV 4 1

https://doi.org/10.1590/s1678-9946202466028

15.

Human-animal interaction and One Health: establishment and validation of the Brazilian version of the Animal Empathy Scale Humananimal Human animal Health
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Savieto, Roberta Maria

; Oliveira, Lucas Pires Garcia

; Borba, Gustavo Benvenutti

; Victor, Elivane da Silva

; Bomfim, Sabrina Bortolossi

; de Oliveira, Letícia Bernardes

; Catissi, Giulia

; Patrício, Karina Pavão

; Kiriyama, Edgard Joseph

; Leão, Eliseth Ribeiro

einstein (São Paulo)

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2024, Volume 22 elocation eAO0685

Abstract: En | Text: En | PDF: En

Objective: To design and validate a Brazilian version of the Animal Empathy Scale, based on the existing Portuguese version. Methods: Content validity assessment was performed by expert judges, and the adapted scale was administered to a sample of 386 participants. Exploratory and confirmatory factor analyses were performed. Results: The bifactorial profile of the scale remained consistent, comprising Empathic Concern for Animals (Cronbach's alpha and McDonald's omega coefficients: 0.75) and Emotional Attachment with Animals (Cronbach's alpha and McDonald's omega coefficients: 0.79). Considering the One Health framework, collaborative, multidisciplinary, and intersectoral approaches are essential for achieving optimal health conditions for people, animals, and the environment given their intricate interconnections. Empathy plays a crucial role in promoting proximity between humans and animals, fostering positive connections that encourage biodiversity conservation. Conclusion: The 13 statements were retained, confirming the validity of the animal empathy scale for use in Brazil, and a Brazilian version of the Animal Empathy Scale was established. Objective Methods judges 38 participants Results consistent Cronbachs Cronbach s McDonalds McDonald coefficients 0.75 075 0 75 0.79. 079 0.79 . 79 0.79) framework collaborative multidisciplinary people animals interconnections conservation Conclusion 1 retained Brazil established 3 0.7 07 7 0.

https://doi.org/10.31744/einstein_journal/2024ao0685

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