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Plant density and planting arrangement for tomato plants of determinate growth
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Campos, Camila M. de A.

; Campos, Luiz F. C.

; Bezerra, Ricardo de S.

; Nascimento, Abadia dos R.

Revista Brasileira de Engenharia Agrícola e Ambiental

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2025, Volume 29 N. 1 elocation e278914

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO A densidade de plantas e o espaçamento correto são fatores fundamentais para alcançar produtividade rentável e qualidade dos frutos em culturas agrícolas. Este estudo teve como objetivo avaliar a produtividade do tomateiro de crescimento determinado e as características físico-químicas dos frutos, em diferentes arranjos de plantio e densidades de plantas. Foram realizados dois experimentos, sendo que no primeiro experimento e no segundo experimento foram utilizados os híbridos CVR-2909 (CVR Plant Breeding) e HMX 7885 (Agristar), respectivamente. Os experimentos foram conduzidos em delineamento de blocos casualizados, com quatro repetições. Foram avaliados dez tratamentos em esquema fatorial duplo (2 × 5). No primeiro fator, foram avaliados dois arranjos de plantio: linhas simples e linhas duplas. No segundo fator, foram avaliadas cinco densidades de plantas: 15, 20, 25, 30 e 35 mil plantas ha-1. Para o híbrido CVR-2909, o cultivo em linhas simples proporcionou maior produtividade, já as maiores densidades de plantas resultaram em menor produção e número de frutos por planta. Para o híbrido HMX-7885, maiores densidades de plantas proporcionaram maior produtividade, porém com menor produção por planta, massa média e número de frutos por planta. Para esse híbrido o arranjo de plantio proporcionou maior taxa de frutos verdes. agrícolas físicoquímicas físico químicas CVR2909 CVR 2909 CVR-290 Breeding 788 Agristar, Agristar , (Agristar) respectivamente casualizados repetições 2 ( 5. 5 . 5) fator duplas 15 20 25 3 ha1. ha1 ha 1. 1 ha-1 CVR2909, 2909, planta HMX7885, HMX7885 7885, HMX-7885 verdes CVR290 290 CVR-29 78 (Agristar ha- HMX788 HMX-788 CVR29 29 CVR-2 7 HMX78 HMX-78 CVR2 CVR- HMX7 HMX-7 HMX-

ABSTRACT Plant density and correct row spacing are fundamental factors for achieving profitable yield and fruit quality in crops. This study aimed to evaluate the yield of tomato plants of determinate growth and the physicochemical characteristics of the fruits in different planting arrangements and plant densities. Two experiments were conducted using the hybrids CVR-2909 (CVR Plant Breeding) and HMX 7885 (Agristar) in the first and second experiments, respectively. The experiments were conducted in a randomized block design with four replicates. Ten treatments were evaluated in a double factorial scheme (2 × 5). Two planting arrangements were evaluated in the first factor: single and double rows. The second factor comprised five plant densities: 15, 20, 25, 30, and 35 thousand plants ha-1. For the CVR-2909 hybrid, single-row cultivation resulted in the highest yield, while higher planting densities gave the lowest yield and number of fruits per plant. For the HMX-7885 hybrid, it was found that higher densities gave higher yields but caused a decreasing effect on fruit production per plant, average fruit mass, and number of fruits per plant. For this hybrid, the planting arrangement provided a higher rate of green fruits. crops CVR2909 CVR 2909 CVR-290 Breeding 788 Agristar (Agristar respectively replicates 2 ( 5. 5 . 5) rows 15 20 25 30 3 ha1. ha1 ha 1. 1 ha-1 hybrid singlerow HMX7885 HMX-788 mass CVR290 290 CVR-29 78 ha- HMX788 HMX-78 CVR29 29 CVR-2 7 HMX78 HMX-7 CVR2 CVR- HMX7 HMX-

https://doi.org/10.1590/1807-1929/agriambi.v29n1e278914

Sporotrichosis in a 9-month-old baby boy: a rare presentation
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Silva, Vivian M. S. C.

; Faver, Hugo M.

; Gushiken-Duarte, Violeta N.

; Alves, Camila A.

; Nascimento, Angela C.

; Simões, Andressa B.

; Murta, Sara M. G. F.

; Cursi, Igor B.

Portuguese Journal of Dermatology and Venereology

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sep 2024, Volume 82 N. 3 Pages 191 - 194

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A esporotricose é uma micose subaguda a crônica causada por espécies do gênero Sporothrix. A forma linfocutânea predomina na maioria dos casos, porém indivíduos imunocomprometidos podem apresentar variantes disseminadas. Embora mais prevalente em adultos, sua ocorrência em lactentes é um fenômeno raro, com fatores de risco e aspectos epidemiológicos pouco estudados. Descrevemos um caso de infecção por esporotricose em criança de 9 meses, que se manifestou por dois nódulos de crescimento progressivo, de consistência mole, localizados nas regiões cervical direita e pré-auricular, associados a uma deterioração na condição geral e febre ao longo de um mês. Apesar de múltiplos tratamentos com antibióticos, não houve melhora das lesões. A cultura do material aspirado de um dos nódulos revelou Sporothrix. O paciente foi então tratado com itraconazol oral, levando à regressão das lesões em 2 meses. A identificação do agente de transmissão neste caso não foi possível. Este relato visa ampliar a compreensão da manifestação da esporotricose em lactentes e fornecer informações valiosas para o aprimoramento de estratégias específicas de prevenção, diagnóstico e tratamento para esse grupo particular de pacientes dermatológicos.

Abstract Sporotrichosis is a subacute to chronic mycosis caused by species of the genus Sporothrix. While the lymphocutaneous form predominates in most cases, immunocompromised individuals may present with disseminated variants. It is more prevalent in adults and rare in infants, with poorly studied risk factors and epidemiological aspects in this age group. We describe a case of sporotrichosis infection in a 9-month-old child, presenting with two progressively growing nodules, soft in consistency, located in the right cervical and pre-auricular regions, associated with a decline in general condition and fever over a month’s duration. Despite multiple oral antibiotics, there was no lesional improvement. Aspiration of one of the nodules, and culture of the secretion revealed Sporothrix. The patient was then treated with oral itraconazole, leading to regression of the lesions within 2 months. The identification of the transmission agent in this case was not possible. This report aims to broaden the understanding of sporotrichosis manifestation in infants and to provide valuable insights for the enhancement of specific preventive, diagnostic, and therapeutic strategies for this age group of dermatological patients.

https://doi.org/10.24875/pjdv.23000107

Stress level and quality of life following pediatric cataract surgery
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Koch, Camila Ribeiro

; Parahyba, Marcelle Oliveira

; Barros, Adriana Nascimento Alves de

; Leite, Marcela Macedo

; Souza, Ângela Cristina Santana

; Bastos, Joana Anjos

Arquivos Brasileiros de Oftalmologia

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2024, Volume 87 N. 3 elocation e2021-0493

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Avaliar a qualidade de vida e o nível de estresse relacionada à função visual após a cirurgia de catarata pediátrica em um hospital público brasileiro. Métodos: Estudo prospectivo em crianças de seis a 14 anos submetidas à cirurgia de catarata. A Escala de Stresse Infantil e o Questionário de Função Visual em Crianças foram usados para avaliar o nível de estresse e a qualidade de vida, respectivamente. Ambos os instrumentos foram aplicados por duas psicólogas antes e após a cirurgia. O exame oftalmológico foi realizado por dois oftalmologistas. Os dados coletados no pré e pós-operatório foram comparados. Resultados: Vinte e três crianças (32 olhos) foram incluídas no estudo, nove delas apresentavam catarata bilateral. A média de idade na cirurgia foi de 9,65±2,26 (6 a 14) anos. Um mês após a cirurgia, o equivalente esférico foi de -0,90 ± 1,66D e a acuidade visual corrigida a distância foi de 0,13 ± 0,10 (0-0,3) LogMAR em casos bilaterais e 0,50 ± 0,39 (0-1,3) LogMAR em casos unilaterais (p<0.01). De acordo com a Escala de Stresse Infantil, 77,7% dos casos de catarata bilaterais, e 57,1% dos casos unilaterais mantiveram o nível de estresse e 34,7% das crianças melhoraram o nível de estresse. A análise do Questionário de Função Visual em Crianças foi baseada em pontuações para saúde geral, saúde geral da visão, competência, personalidade e tratamento. Após a cirurgia de catarata, 78,2% dos pacientes melhoraram ou mantiveram o escore do Questionário de Função Visual em Crianças na saúde geral, 82,6% na saúde geral da visão, 95,6% na competência, 56,5% na personalidade e 78,2% no tratamento. Conclusão: A cirurgia de catarata pediátrica melhora a função visual e a qualidade de vida em pacientes submetidos a procedimento cirúrgico, sem aumentar o nível de estresse. Objetivo brasileiro Métodos 1 respectivamente oftalmologistas pósoperatório pós operatório comparados Resultados 32 (3 olhos estudo bilateral 965226 9 65 2 26 9,65±2,2 6 ( 0,90 090 0 90 -0,9 166D D 66D 013 13 0,1 010 10 00,3 003 0,3 3 (0-0,3 050 50 0,5 039 39 01,3 1,3 (0-1,3 p<0.01. p001 p p<0.01 . 01 (p<0.01) 777 77 7 77,7 571 57 57,1 347 34 34,7 visão competência tratamento 782 78 78,2 826 82 82,6 956 95 95,6 565 56 5 56,5 Conclusão cirúrgico 96522 9,65±2, 0,9 09 -0, 0, 00 00, 03 (0-0, 05 01, 1, (0-1, p00 p<0.0 (p<0.01 77, 57, 34, 78, 8 82, 95, 56, 9652 9,65±2 -0 (0-0 (0-1 p0 p<0. (p<0.0 965 9,65± - (0- p<0 (p<0. 96 9,65 (0 p< (p<0 9,6 (p< 9, (p

ABSTRACT Purpose: To evaluate the quality of life and stress level related to visual function following pediatric cataract surgery in a Brazilian public hospital. Methods: This prospective study analyzed children aged 6-14 years old who underwent cataract surgery. The Childhood Stress Scale and Children’s Visual Function Questionnaire (CVFQ) were used to assess stress levels and quality of life, respectively. Both instruments were applied by two psychologists before and after the surgery. Eye examination was performed by two ophthalmologists. Preoperative and postoperative data were compared. Results: In total, 23 children (32 eyes) were enrolled in the study, of which 9 had bilateral cataracts. The average age group at the time of surgery was 9.65 ± 2.26 (6-14) years old. One month after the surgery, the spherical equivalent was -0.90 ± 1.66D, and the corrected distance visual acuity was 0.13 ± 0.10 (0-0.3) LogMAR in bilateral cases and 0.50 ± 0.39 (0-1.3) LogMAR in unilateral cases (p<0.01). According to the Childhood Stress Scale, 77.7% of the bilateral cases and 57.1% of the unilateral cases had stable stress levels, and 34.7% of the children improved their stress level. The analysis of the CVFQ was based on scores for general health, general vision health, competence, personality, and treatment. After cataract surgery, 78.2% of the patients had improved or maintained CVFQ scores in the general health domain; 82.6%, general vision health; 95.6%, competence; 56.5%, personality; and 78.2%, treatment. Conclusion: Pediatric cataract surgery improves the visual function and the quality of life even in patients undergoing surgical procedures, without increasing the stress levels. Purpose hospital Methods 614 6 14 6-1 Childrens Children s (CVFQ respectively ophthalmologists compared Results total 2 32 (3 eyes cataracts 965 65 9.6 226 26 2.2 (6-14 0.90 090 0 90 -0.9 166D D 1 66D 1.66D 013 13 0.1 010 10 00.3 003 0.3 3 (0-0.3 050 50 0.5 039 39 01.3 1.3 (0-1.3 p<0.01. p001 p p<0.01 . 01 (p<0.01) 777 77 7 77.7 571 57 57.1 347 34 34.7 competence personality treatment 782 78 78.2 domain 826 82 82.6% 956 95 95.6% 565 56 5 56.5% Conclusion procedures 61 6- ( 96 9. 22 2. (6-1 0.9 09 -0. 0. 00 00. 03 (0-0. 05 01. 1. (0-1. p00 p<0.0 (p<0.01 77. 57. 34. 78. 8 82.6 95.6 56.5 (6- -0 (0-0 (0-1 p0 p<0. (p<0.0 82. 95. 56. (6 - (0- p<0 (p<0. (0 p< (p<0 (p< (p

https://doi.org/10.5935/0004-2749.2021-0493

Criação e desenvolvimento de grupos de apoio para o autocuidado em hanseníase em um estado do Nordeste brasileiro
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Nascimento, Raphaela Delmondes do

; Sousa, Islândia Maria Carvalho de

; Melo, Camila Pimentel Lopes de

; Santos, Danielle Christine Moura dos

Physis: Revista de Saúde Coletiva

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2024, Volume 34 elocation e34012

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo Compreender a criação e desenvolvimento de grupos de apoio para o autocuidado em hanseníase em um estado do Nordeste brasileiro. Métodos Estudo qualitativo realizado em três grupos no Nordeste do Brasil, entre fevereiro e dezembro de 2019. A coleta de dados englobou entrevistas, observação participante e análise documental. Os dados foram analisados segundo a técnica de análise de conteúdo a partir dos temas preestabelecidos: implantação, organização e continuidade dos grupos. Resultados A implantação dos grupos apresentou como motivos comuns a necessidade de ampliação dos cuidados, e de otimização do tempo de trabalho. O estigma e questões da organização dos serviços foram obstáculos para a implantação. O fator mais relevante para a continuidade dos grupos foi o envolvimento dos coordenadores nas atividades. O apoio de atores externos como ONG e universidades foram relevantes para a implantação e continuidade. Considerações finais As similaridades e diferenças dos grupos relacionam-se aos participantes, à indução e apoio da política de saúde e às interferências de atores externos. Grupos de apoio para o autocuidado em hanseníase são espaços que potencializam a prática de cuidado. O estudo contribui com a implantação ou reorganização de grupos de apoio ao autocuidado.

Abstract Objective To understand the creation and development of support groups for leprosy in a state in the northeast of Brazil. Methods Qualitative study conducted with three groups in northeast Brazil, from February to December 2019. Data collection included interviews, participant observation, and document analysis. Data were analyzed using the content analysis technique, considering preestablished topics: implementation, organization, and continuity of the groups. Results The most common reasons presented by the groups for the implementation were the needs to expand care and optimize working time. The stigma and service organization issues were obstacles to implementation. The most relevant factor for the continuity of groups was the involvement of the coordinators in the activities. Support from external actors, such NGOs and universities, was relevant to implementation and continuity. Final considerations Similarities and differences among groups are related to participants, actions to foster the groups, health policy support, and interference from external actors. Support groups for leprosy self-care are spaces that strengthen the practice of care. This study contributed to implement or reorganize self-care support groups.

https://doi.org/10.1590/s0103-7331202434012pt

Intervenções educativas para prevenção e conduta dos eventos adversos pós-vacinação: uma revisão sistemática
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Vasconcelos, Débora Amorim de

; Santos, Alberto Matos dos

; Nascimento, Jéssica Carvalho

; Silva, Camila Tahis dos Santos

; Menezes, Andreia Freire de

; Barreiro, Maria do Socorro Claudino

; Ferreira, Camila Belo Tavares

; Silva, Glebson Moura

Ciência & Saúde Coletiva

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2024, Volume 29 N. 7 elocation e02242024

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract This study investigated educational interventions for the prevention and management of adverse events following immunisation. This a systematic review was conducted by examining observational studies, with no restriction as to language or year, registered in PROSPERO with the identifier CRD42022313144 and by searching the MEDLINE, LILACS, Embase, CINAHL and Scopus databases. Two researchers selected the studies, extracted the data and assessed the risk of study bias; disagreements were resolved by a third researcher. A total of six articles met the inclusion criteria of the systematic review and the studies reported significant post-intervention improvements in staff conduct in relation to immunisation. It was concluded that educational strategies that lead to continued professional development in relation to vaccination in primary care were effective in reducing and/or eradicating immunisation errors and adverse events following immunisation.

Resumo O estudo tem como objetivo investigar as intervenções educativas para a prevenção e conduta dos eventos adversos pós-vacinação. Trata-se de uma revisão sistemática realizada por meio da análise de estudos observacionais sem restrição de idioma e ano com registro no PROSPERO pelo identificador CRD42022313144 e busca nas bases de dados MEDLINE, LILACS, Embase, CINAHL e Scopus. Dois pesquisadores selecionaram os estudos, extraíram os dados e avaliaram o risco de viés, as discordâncias foram resolvidas por um terceiro pesquisador. Atenderam os critérios de inclusão da revisão sistemática um total de seis artigos e os estudos apresentaram melhoras significativas pós-intervenção na conduta dos profissionais em relação à imunização. Conclui-se que o fornecimento de estratégias educativas de educação permanente no âmbito vacinal da atenção primária é eficaz para reduzir e/ou erradicar os erros de imunização e eventos adversos pós-vacinação.

https://doi.org/10.1590/1413-81232024297.02242024

Multimorbidade e utilização de serviços de saúde no município de São Paulo, Brasil: prevalência e fatores associados
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Aguiar, Ricardo Goes de

; Monteiro, Camila Nascimento

; Castro, Shamyr Sulyvan de

; Figueiredo, Tatiane Kosimenko Ferrari

; Goldbaum, Moisés

; Cesar, Chester Luiz Galvão

Ciência & Saúde Coletiva

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2024, Volume 29 N. 9 elocation e15002022

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The scope of this paper was to estimate the prevalence of multimorbidity in the city of São Paulo and to verify the factors associated with the utilization of the health services. It involved a population based cross-sectional study based on data from the Health Survey in the city of São Paulo, in which descriptive analysis was conducted, and logistic regression models were developed using multimorbidity and sociodemographic independent variables, living conditions and use of health services as the outcome. A total of 3,184 individuals aged 20 years or older participated, with a mean age of 43.8 years. The prevalence of multimorbidity was 50.7% among women, 62.5% among those who reported some health problem and 55.1% among those who had recourse to health services in the last 2 weeks. A higher prevalence was identified among those who used the health service due to a mental health problem (66.1%), and in those who reported higher health expenditures in the preceding month (55.4%). Multimorbidity was more frequently associated with aging, in the population with a higher economic status, with worse self-rated health, who frequented health services for 6 months or less, who reported a health problem, or who had a health plan and opted for polypharmacy.

Resumo O objetivo foi estimar a prevalência de multimorbidade no município de São Paulo e verificar os fatores associados à utilização de serviços de saúde. Estudo transversal de base populacional a partir do Inquérito de Saúde do Município de São Paulo (ISA-Capital 2015), em que foi realizada análise descritiva e foram elaborados modelos de regressão logística utilizando como desfecho a multimorbidade e variáveis independentes sociodemográficas, de condições de vida e utilização de serviços de saúde. Participaram 3.184 indivíduos com 20 anos ou mais, idade média de 43,8 anos. A prevalência de multimorbidade foi de 50,7% entre as mulheres, 62,5% entre os que relataram algum problema de saúde e 55,1% entre os que utilizaram serviços de saúde nas duas últimas semanas. Foi identificada maior prevalência nos indivíduos que usaram serviço de saúde por problema de saúde mental (66,1%) e que informaram maiores despesas com saúde no último mês (55,4%). A multimorbidade foi mais frequente com o envelhecimento, na população com nível econômico mais elevado, com pior autoavaliação de saúde, que utilizou serviços de saúde há seis meses ou menos, que relatou problema de saúde, que tinha plano de saúde e fazia uso da polifarmácia.

https://doi.org/10.1590/1413-81232024299.15002022

In silico and in vitro Studies Evaluating the Promising Antiureolytic Activity of Schiff’s Base 4-(3-Hydroxybenzylideneamino)phenol and Its Amine Derivative Schiffs Schiff s 43Hydroxybenzylideneaminophenol Hydroxybenzylideneaminophenol 4 3 Hydroxybenzylideneamino phenol
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Dohanik, Caroline S.

; Pereira, Camila P.

; Oliveira, Breno G. F. de

; Nascimento, Igor J. S.

; Nascimento, Amanda Luise A.

; Santos, Josué C. C.

; Aquino, Thiago M. de

; Castilho, Rachel O.

; Modolo, Luzia V.

; Fátima, Ângelo de

; Goulart, Gisele A. C.

Journal of the Brazilian Chemical Society

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2024, Volume 35 N. 6 elocation e-20240001

Abstract: En | Text: En | PDF: En

Urea is the most widely used nitrogen fertilizer worldwide. However, ammonia volatilization, resulting from applying urea to the soil surface, causes economic and environmental losses; thus, urease inhibitors have been developed to mitigate these losses. In this work, the anti-ureolytic activity of Schiff’s base 4-(3-hydroxybenzylideneamino) phenol (3B4) and its amine-derived (3B4a) was evaluated. The most promising urease inhibitor in soil was 3B4 (55.0 ± 3.9% inhibition), with comparable results to N-(butyl) thiophosphoric triamide (p = 0.659). In the in vitro analysis (Canavalia ensiformis), the results of anti-ureolytic activity were similar, 22.6 ± 6.9% for 3B4 and 24.2 ± 9.6% for 3B4a. Biophysical interaction studies were also carried out through molecular docking studies and molecular fluorescence spectroscopy. These studies showed that both substances are preferentially competitive inhibitors, with the interaction between 3B4a and urease forming a more stable complex. In the analysis by Fourier transform infrared spectroscopy, no interaction was observed when 3B4 or 3B4a was mixed with urea (1:1) for 48 h, providing evidence of compatibility. Thus, the Schiff base 3B4 and its corresponding amine 3B4a may represent potential additives for urea fertilization aiming to assist in the urease inhibition process. worldwide However volatilization surface losses thus work antiureolytic anti ureolytic Schiffs s 43hydroxybenzylideneamino hydroxybenzylideneamino 4 3 4-(3-hydroxybenzylideneamino B (3B4 aminederived derived Ba (3B4a evaluated 3B 55.0 550 55 0 (55. 39 9 3.9 inhibition, , inhibition) Nbutyl N butyl N-(butyl p 0.659. 0659 0.659 . 659 0.659) Canavalia ensiformis, ensiformis ensiformis) similar 226 22 6 22. 69 6.9 242 24 2 24. 96 9.6 spectroscopy complex 11 1 (1:1 h compatibility Thus process (3B 55. 5 (55 3. 065 0.65 65 6. 9. (1: (5 06 0.6 (1 ( 0.

https://doi.org/10.21577/0103-5053.20240001

Quantile regression for genomic selection of growth curves
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Nascimento, Ana Carolina Campana

; Azevedo, Camila Ferreira

; Barreto, Cynthia Aparecida Valiati

; Oliveira, Gabriela França

; Nascimento, Moysés

Acta Scientiarum. Agronomy

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2024, Volume 46 elocation e65081

Abstract: En | Text: En | PDF: En

ABSTRACT. This study evaluated the efficiency of genome-wide selection (GWS) based on regularized quantile regression (RQR) to obtain genomic growth curves based on genomic estimated breeding values (GEBV) of individuals with different probability distributions. The data were simulated and composed of 2,025 individuals from two generations and 435 markers randomly distributed across five chromosomes. The simulated phenotypes presented symmetrical, skewed, positive, and negative distributions. Data were analyzed using RQR considering nine quantiles (0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, and 0.9) and traditional methods of genomic selection (specifically, RR-BLUP, BLASSO, BayesA, and BayesB). In general, RQR-based estimation of the GEBV was efficient-at least for a quantile model, the results obtained were more accurate than those obtained by the other evaluated methodologies. Specifically, in the symmetrical-distribution scenario, the highest accuracy values were obtained for the parameters with the models RQR0.4, RQR0.3, and RQR0.4. For positive skewness, the models RQR0.2, RQR0.3, and RQR0.1 presented higher accuracy values, whereas for negative skewness, the best model was RQR0.9. Finally, the GEBV vectors obtained by RQR facilitated the construction of genomic growth curves at different levels of interest (quantiles), illustrating the weight-age relationship. ABSTRACT genomewide genome wide GWS (GWS (RQR (GEBV distributions 2025 2 025 2,02 43 chromosomes symmetrical skewed 0.1, 01 0 1 (0.1 02 0.2 03 3 0.3 04 4 0.4 05 5 0.5 06 6 0.6 07 7 0.7 08 8 0.8 0.9 09 9 specifically, specifically (specifically RRBLUP, RRBLUP RR BLUP, BLUP RR-BLUP BLASSO BayesA BayesB. BayesB . BayesB) general RQRbased efficientat efficient methodologies Specifically symmetricaldistribution distribution scenario RQR04 RQR0 RQR0.4 RQR03 RQR0.3 skewness RQR02 RQR0.2 RQR01 RQR0. RQR09 RQR0.9 Finally quantiles, , (quantiles) weightage weight age relationship 202 2,0 0.1 (0. 0. (quantiles 20 2, (0 (

https://doi.org/10.4025/actasciagron.v46i1.65081

Criação e desenvolvimento de grupos de apoio para o autocuidado em hanseníase em um estado do Nordeste brasileiro
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Nascimento, Raphaela Delmondes do

; Sousa, Islândia Maria Carvalho de

; Melo, Camila Pimentel Lopes de

; Santos, Danielle Christine Moura dos

Physis: Revista de Saúde Coletiva

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2024, Volume 34 elocation e34012

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/s0103-7331202434012pt

10.

Amphibians and reptiles of the Refúgio Biológico Bela Vista – Itaipu Dam, state of Paraná, southern Brazil Dam Paraná
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Vicente-Ferreira, Gabriel S.

; do Nascimento, Eloize F.

; Batista, Camila S.

; Kardush, Tarik A.

; Reyes, Kathia L.B.

; Garey, Michel V.

Biota Neotropica

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2024, Volume 24 N. 1 elocation e20231526

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Informações sobre a ocorrência de espécies são fundamentais para a compreensão da distribuição da biodiversidade. Porém, a biodiversidade do oeste do Estado do Paraná tem sido historicamente menos estudada, especialmente a de anfíbios e répteis. Por esse motivo, apresentamos a primeira lista de espécies de répteis do oeste do Estado do Paraná e ampliamos a lista atual de anuros para o município de Foz do Iguaçu. A lista de espécies foi baseada em um estudo sistemático de campo realizado em uma área de conservação dentro da Usina Hidrelétrica Itaipu Binacional. Integramos a lista de espécies com observações de espécies anteriores disponíveis na literatura para o mesmo local onde nossa amostragem foi realizada. Um total de 41 espécies são apresentadas. Todas as espécies de anuros encontradas foram registradas em campo; entretanto, das 22 espécies de répteis registradas, três foram registros obtidos antes deste estudo. Todas as espécies foram classificadas como “Pouco Preocupante” e/ou tinham status de “População Estável” de acordo com a IUCN. A suficiência amostral foi alcançada para anuros, mas não para répteis, provavelmente devido à baixa abundância de diversas espécies de serpentes. A espécie de anuro mais abundante foi Dendropsophus nanus, da família Hylidae, enquanto Leptodactylus plaumanni e Scinax squalirostris foram representados por apenas um indivíduo cada. O lagarto Salvator merianae foi o réptil mais abundante, e sete espécies foram representadas por um indivíduo cada. O método de amostragem mais bem sucedido para anuros adultos foi a busca ativa em corpos d’água, enquanto a maioria das espécies de répteis foi observada por encontros acidentais e não através de um método de amostragem sistematizado. Descobrimos que a composição da herpetofauna do Refúgio Biológico Bela Vista foi semelhante à de outras comunidades do estado do Paraná que também ocorrem dentro da Floresta Estacional Semidecidual. Por fim, como informações adicionais à lista de espécies, oferecemos chaves de identificação das espécies e discutimos sobre a importância da área de Itaipu para abrigar a diversidade de anuros e répteis da região. Porém estudada motivo Iguaçu Binacional realizada 4 apresentadas entretanto 2 Pouco Preocupante eou ou População Estável IUCN serpentes nanus Hylidae cada dágua, dágua d água, água d’água sistematizado Semidecidual fim região

Abstract Information regarding species occurrence is fundamental to understanding biodiversity distribution. However, the biodiversity from the west of the state of Paraná has been historically less studied, especially amphibians and reptiles. For this reason, we present the first reptile list of species from the west of the state of Paraná and extend the current list of anurans for the municipality of Foz do Iguaçu. The species list was based on a systematic field study conducted at Refúgio Biológico Bela Vista (RBV) a conservation area within the Hydroelectric Power Itaipu Binacional. We integrated the species list with previous species observations available in the literature for the same place where our sampling was conducted. A total of 41 species of amphibians and reptiles are presented. All amphibians species found were recorded in the field; however, from the 22 species of reptiles recorded, three were historical records obtained before this study. Species were all classified as Least Concern and/or had stable populational status according to the IUCN. Sampling sufficiency was achieved for anurans but not for reptiles, probably due to low abundance of several snake species. The most abundant species of anuran was Dendropsophus nanus, from the Hylidae family, whereas Leptodactylus plaumanni and Scinax squalirostris were represented by only one individual each. The lizard Salvator merianae was the most abundant reptile, and seven species were represented by only one individual each. The most successful sampling method for adult anurans was active search in water bodies whereas most of reptile species were observed by accidental encounters and not through a systematic sampling method. We found that herpetofauna composition from RBV was similar to other communities from Paraná state that also occur within the Semideciduous Seasonal Forest. Finally, as additional information to the species list, we offer species identification keys and discuss the importance of Refúgio Biológico Bela Vista to harbor the anuran and reptile diversity of the region. distribution However studied reason Iguaçu (RBV Binacional 4 presented however 2 andor or IUCN nanus family each Forest Finally region

https://doi.org/10.1590/1676-0611-bn-2023-1526

11.

Variation in soil penetration resistance as a function of soil moisture under crop management systems
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Paiva Filho, Silvio Vasconcelos de

; Tavares, Rose Luiza Moraes

; Ferreira, Camila Jorge Bernabé

; Santos, Gilmar Oliveira

; Nascimento, Hemython Luis Bandeira

Revista Ciência Agronômica

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2024, Volume 55 elocation e20238683

Abstract: En | Text: En | PDF: En

ABSTRACT The objective of this study was to monitor the temporal variation in penetration resistance (PR) after soil saturation under different management systems in three areas of the Cerrado biome: two in no-till systems (NT with 3 and 10 years of implementation) and one of crop-livestock integration (CL with 9 years of implementation) with soybean/forage succession. Four transects were delimited in each area. The delimited area was saturated and the PR measurements were performed daily for 11 days at 10 transect points, up to 0.40 m of depth. Soil moisture was determined with PR measurements, soil hydraulic conductivity, and organic carbon. PR values were more significant in the 0.10 - 0.20 m layer than in the 0.0 - 0.10 and 0.20 - 0.40 m layers. The NT-3 area showed a lower PR value (1.65 MPa) than the area under NT-10 and CL-9, with 2.48 and 2.69 MPa, respectively. Thus, critical soil moisture values, that is, soil moisture values most susceptible to soil compaction were determined. Thus, in the NT-3 area, the critical moisture was 0.20 kg kg-1, in the NT-10, ranged from 0.19 - 0.20 kg kg-1, and in the CL-9, between 0.23 and 0.20 kg kg-1. Monitoring soil moisture can prevent management operations from restricting root growth. (PR biome notill no till NT 1 implementation croplivestock crop livestock CL soybeanforage soybean forage succession points 040 0 40 0.4 depth conductivity carbon 010 0.1 020 20 0.2 00 0. layers NT3 NT- 1.65 165 65 (1.6 MPa NT10 NT-1 CL9, CL9 9, CL-9 248 2 48 2.4 269 69 2.6 respectively Thus is kg1, kg1 1, kg-1 NT10, 10, 019 19 023 23 kg1. 1. growth 04 4 01 02 1.6 16 6 (1. NT1 CL- 24 2. 26 kg- (1 (

https://doi.org/10.5935/1806-6690.20240043

12.

Chikungunya chronic arthralgia: impact on general and mental health and absenteeism from work arthralgia
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Santos, Lorena Gomes

; Jacob-Nascimento, Leile Camila

; Anjos, Rosângela Oliveira

; Portilho, Moyra Machado

; Cavalcante, Viviane Machicado

; Paz, Adriane Souza

; Santiago, Mittermayer Barreto

; Cardoso, Cristiane Wanderley

; Reis, Mitermayer Galvão

; Ribeiro, Guilherme Sousa

Revista da Sociedade Brasileira de Medicina Tropical

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2024, Volume 57 elocation e00716-2024

Abstract: En | Text: En | PDF: En

ABSTRACT Background: This study investigated the self-rated general health, mental health, and work absenteeism among patients with laboratory-confirmed chikungunya. Methods: Telephone interviews were conducted with 63 patients ≥22 months after infection. Results: Patients who reported (N=42) or did not report (N=21) chronic arthralgia, defined by duration ≥90 days, had different frequencies for low scores for general health (68.3% vs. 30.0%, respectively; prevalence ratio, 95% confidence interval: 2.3, 1.1-4.6), symptoms of depression (31.7% vs. 15.0%; 2.1, 0.7-6.6), symptoms of anxiety (43.9% vs. 35.0%; 1.3, 0.6-2.5), and work absenteeism (76.5% and 40.0%; 1.9, 0.9-4.2). Conclusions: Chikungunya chronic arthralgia impacts long-term health and work. Background selfrated self rated laboratoryconfirmed laboratory confirmed chikungunya Methods 6 22 ≥2 infection Results N=42 N42 N 42 (N=42 N=21 N21 21 (N=21 90 ≥9 days 68.3% 683 68 3 (68.3 vs 300 30 0 30.0% respectively ratio 95 interval 23 2 2.3 1.14.6, 1146 1.1 4.6 , 1 4 1.1-4.6) 31.7% 317 31 7 (31.7 15.0% 150 15 2.1 0.76.6, 0766 0.7 6.6 0.7-6.6) 43.9% 439 43 9 (43.9 35.0% 350 35 13 1.3 0.62.5, 0625 0.6 2.5 5 0.6-2.5) 76.5% 765 76 (76.5 40.0% 400 40 19 1.9 0.94.2. 0942 0.9 4.2 . 0.9-4.2) Conclusions longterm long term ≥ N=4 N4 (N=4 N=2 N2 (N=2 68.3 (68. 30.0 2. 14 1.14.6 114 11 1. 46 4. 1.1-4.6 31.7 (31. 15.0 0.76.6 076 07 0. 66 6. 0.7-6.6 43.9 (43. 35.0 62 0.62.5 062 06 25 0.6-2.5 76.5 (76. 40.0 94 0.94.2 094 09 0.9-4.2 N= (N= 68. (68 30. 1.14. 1.1-4. 31. (31 15. 0.76. 0.7-6. 43. (43 35. 0.62. 0.6-2. 76. (76 40. 0.94. 0.9-4. (N (6 1.14 1.1-4 (3 0.76 0.7-6 (4 0.62 0.6-2 (7 0.94 0.9-4 ( 1.1- 0.7- 0.6- 0.9-

https://doi.org/10.1590/0037-8682-0149-2024

13.

Production and biochemical and biophysical characterization of fibrinolytic protease of a Mucor subtilissimus strain isolated from the caatinga biome
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CONNIFF, AMANDA EMMANUELLE S.

; NASCIMENTO, THIAGO P.

; COSTA, ROMERO MARCOS P.B.

; BREYDO, LEONID

; PORTO, CAMILA S.

; CONVERTI, ATTILIO

; SIQUEIRA, JOYCE G.W.

; TEIXEIRA, JOSE ANTONIO

; CAMPOS-TAKAKI, GALBA MARIA DE

; UVERSKY, VLADIMIR N.

; PORTO, ANA LÚCIA F.

; PORTO, TATIANA S.

Anais da Academia Brasileira de Ciências

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2024, Volume 96 Suppl. 1 elocation e20230616

Abstract: En | Text: En | PDF: En

Abstract Cardiovascular diseases, resulting from the deposition of clots in blood vessels, are the leading cause of death worldwide. Fibrinolytic enzymatic activity can catalyze blood clot degradation. Findings show that 36 fungal isolates recovered from Caatinga soils have the potential to produce fibrinolytic protease under submerged conditions. About 58 % of the isolates displayed fibrinolytic activity above 100 U/mL, with Mucor subtilissimus UCP 1262 being the most active. The protease was biochemically and biophysically characterized, showing that the enzyme had a high affinity for SAApNA substrate and was significantly inhibited by fluoride methyl phenyl sulfonyl-C7H7FO2S, suggesting that it is a chymotrypsin-like serine protease. The highest enzyme activity was detected at pH 5.0 and 28 °C. This fibrinolytic protease’s far-UV circular dichroism (CD) showed that its secondary structure was primarily α-helical. The purified fibrinolytic enzyme may represent a novel therapeutic agent for treating thrombosis. At temperatures above 65 °C, the enzyme lost all its secondary structure. Its melting temperature was 58.1 °C, the denaturation enthalpy 85.1 kcal/mol, and the denaturation entropy 0.26 kcal/K∙mol. diseases vessels worldwide degradation 3 conditions 5 10 UmL U mL U/mL 126 active characterized sulfonylC7H7FO2S, sulfonylC7H7FO2S sulfonylCHFOS sulfonyl C7H7FO2S, C7H7FO2S C H FO S sulfonyl-C7H7FO2S chymotrypsinlike chymotrypsin like 50 0 5. 2 °C proteases s farUV far UV CD (CD αhelical. αhelical α helical. helical α-helical thrombosis 6 581 1 58. 851 85 85. kcalmol kcal mol kcal/mol 026 26 0.2 kcalKmol K kcal/K∙mol 12 sulfonylC CHFOS 8 02 0.

https://doi.org/10.1590/0001-3765202420230616

14.

Coleoptera of Brazil: what we knew then and what we know now. Insights from the Catálogo Taxonômico da Fauna do Brasil Brazil now
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Caron, Edilson

; Monné, Marcela L.

; Ferreira, Vinicius S.

; Costa, Cleide

; Cupello, Mario

; Aloquio, Sergio

; Linzmeier, Adelita M.

; Vaz-de-Mello, Fernando Z.

; Leivas, Fernando W.T.

; Souza-Gonçalves, Igor

; Mermudes, José R.M.

; Almeida, Lúcia M.

; Moura, Luciano de A.

; Ferreira Júnior, Nelson

; Grossi, Paschoal C.

; Vanin, Sergio A.

; Ślipiński, Adam

; Anichtchenko, Alexander

; Newton, Alfred F.

; Sampaio, Aline

; Carelli, Allan

; Puker, Anderson

; Ferreira, André da S.

; Fernandes, André S.

; Roza, André S.

; Cline, Andrew

; Sampaio, Brunno H.L.

; Clarkson, Bruno

; Castro, Camila F. de

; Bicho, Carla de L.

; Benetti, César J.

; Ribeiro-Costa, Cibele S.

; Lopes-Andrade, Cristiano

; Manfio, Daiara

; Colpani, Daniara

; Basílio, Daniel S.

; Bená, Daniela de C.

; Pollock, Darren A.

; Souza, Diego de S.

; Rodrigues, Diego F.

; Chandler, Donald S.

; Nascimento, Elynton A. do

; Spiessberger, Erich L.

; Agrain, Federico A.

; Barbosa, Felipe F.

; Shockley, Floyd

; Nascimento, Francisco E. de L.

; Biffi, Gabriel

; Powell, Gareth S.

; Morse, Geoffrey E.

; Flores, Gustavo E.

; Escalona, Hermes

; Quintino, Hingrid Y.S.

; Rainho, Hugo L.

; Maddalena, Italo S.C.P.

; Hájek, Jiří

; McHugh, Joseph V.

; Botero, Juan P.

; Fuhrmann, Juares

; Churata-Salcedo, Julissa M.

; Vieira, Letícia M.

; Silveira, Luiz F.L. da

; Cruz, Luiza S. da

; Sekerka, Lukás

; Bologna, Marco A.

; Bevilaqua, Marcus V.O.

; Passos, Maria I.

; Chamorro, Maria L.

; Cherman, Mariana A.

; Bento, Matheus

; Gimmel, Matthew

; Segura, Melissa O.

; Ivie, Michael A.

; Thomas, Michael C.

; Monné, Miguel A.

; Lord, Nathan

; Hamada, Neusa

; Degallier, Nicolas

; Santos, Paula B. dos

; Duarte, Paulo R.M.

; Gnaspini, Pedro

; Bulirsch, Petr

; Regalin, Renato

; Leschen, Richard A.B.

; Constantin, Robert

; Corrêa, Rodrigo C.

; Gerstmeier, Roland

; Rosa, Simone P.

; Campos, Stéphanie V.N.

; Peck, Stewart B.

; Pacheco, Thaynara L.

; Polizei, Thiago T.S.

; McElrath, Thomas C.

; Grzymala, Traci L.

; Smith, Trevor R.

; Costa-Silva, Vinicius da

; Sandoval-Gómez, Vivian E.

; Sousa, Wesley O. de

; Tomaszewska, Wioletta

Zoologia (Curitiba)

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2024, Volume 41 elocation e23072

Abstract: En | Text: En | PDF: En

ABSTRACT In 2000, Cleide Costa published a paper presenting the state of knowledge of the Neotropical Coleopte ra, with a focus on the Brazilian fauna. Twenty-four years later, thanks to the development of the Coleoptera section of the Taxonomic Catalog of the Brazilian Fauna (CTFB - Catálogo Taxonômico da Fauna do Brasil) through the collaboration of 100 coleopterists from all over the globe, we can build on Costa’s work and present an updated overview of the state of knowledge of the beetles from Brazil. There are currently 35,699 species in 4,958 genera and 116 families known to occur in the country, including representatives of all extant suborders and superfamilies. Our data show that the Brazilian beetle fauna is the richest on the planet, concentrating 9% of the world species diversity, with some estimates accounting to up to 15% of the global total. The most diverse family in numbers of genera is Cerambycidae (1,056 genera), while in number of species it is Chrysomelidae (6,079 species). Conotrachelus Dejean, 1835 (Curculionidae) is the most species-rich genus, with 570 species. The French entomologist Maurice Pic is the author who has contributed the most to the naming of species recorded from Brazil, with 1,794 valid names in 36 families, whereas the Brazilians Ubirajara R. Martins and Maria Helena M. Galileo are the only ones among the top-ten authors to have named species in the 21st century. Currently, approximately 144 new species of Brazilian beetles are described each year, and this average is projected to increase in the next decade to 180 species per year, or about one new Brazilian beetle every two days. 2000 ra Twentyfour Twenty four later CTFB Brasil 10 globe Costas s Brazil 35699 35 699 35,69 4958 4 958 4,95 11 country superfamilies planet 9 diversity 15 total 1,056 1056 1 056 (1,05 genera, , genera) 6,079 6079 6 079 (6,07 . species) Dejean 183 Curculionidae (Curculionidae speciesrich rich genus 57 1794 794 1,79 3 R M topten top ten st century Currently 14 year 18 days 200 3569 69 35,6 495 95 4,9 1,05 105 05 (1,0 6,07 607 07 (6,0 5 179 79 1,7 20 356 35, 49 4, 1,0 0 (1, 6,0 60 (6, 17 7 1, 2 (1 6, (6 (

https://doi.org/10.1590/s1984-4689.v41.e23072

15.

Brazilian consensus recommendations on the diagnosis and treatment of autoimmune encephalitis in the adult and pediatric populations
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Dutra, Lívia Almeida

; Silva, Pedro Victor de Castro

; Ferreira, João Henrique Fregadolli

; Marques, Alexandre Coelho

; Toso, Fabio Fieni

; Vasconcelos, Claudia Cristina Ferreira

; Brum, Doralina Guimarães

; Pereira, Samira Luisa dos Apóstolos

; Adoni, Tarso

; Rocha, Leticia Januzi de Almeida

; Sampaio, Leticia Pereira de Brito

; Sousa, Nise Alessandra de Carvalho

; Paolilo, Renata Barbosa

; Pizzol, Angélica Dal

; Costa, Bruna Klein da

; Disserol, Caio César Diniz

; Pupe, Camila

; Valle, Daniel Almeida do

; Diniz, Denise Sisterolli

; Abrantes, Fabiano Ferreira de

; Schmidt, Felipe da Rocha

; Cendes, Fernando

; Oliveira, Francisco Tomaz Meneses de

; Martins, Gabriela Joca

; Silva, Guilherme Diogo

; Lin, Katia

; Pinto, Lécio Figueira

; Santos, Mara Lúcia Schimtz Ferreira

; Gonçalves, Marcus Vinícius Magno

; Krueger, Mariana Braatz

; Haziot, Michel Elyas Jung

; Barsottini, Orlando Graziani Povoas

; Nascimento, Osvaldo José Moreira do

; Nóbrega, Paulo Ribeiro

; Proveti, Priscilla Mara

; Castilhos, Raphael Machado do

; Daccach, Vanessa

; Glehn, Felipe von

Arquivos de Neuro-Psiquiatria

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2024, Volume 82 N. 7 elocation s00441788586

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Antecedentes Encefalites autoimunes (EAIs) são um grupo de doenças inflamatórias caracterizadas pela presença de anticorpos contra antígenos neuronais e gliais, que ocasionam sintomas psiquiátricos subagudos, queixas de memória e distúrbios anormais do movimento. A maioria dos pacientes é jovem, e o atraso no tratamento está associado a pior prognóstico. Objetivo Com o apoio da Academia Brasileira de Neurologia (ABN) e da Sociedade Brasileira de Neurologia Infantil (SBNI), desenvolvemos um consenso sobre o diagnóstico e o tratamento da EAIs no Brasil utilizando a metodologia Delphi. Métodos Um total de 25 especialistas, incluindo neurologistas e neurologistas infantis, foram convidados a participar. Resultados Os especialistas concordaram que os pacientes com critérios de possíveis EAIs devem ser submetidos ao rastreio de anticorpos antineuronais no soro e no líquido cefalorraquidiano (LCR) por meio das técnicas de ensaio baseado em tecidos (tissue-based assay, TBA, em inglês) e ensaio baseado em células (cell-based assay, CBA, em inglês). As crianças também devem ser submetidas ao rastreio de de anticorpo contra a glicoproteína da mielina de oligodendrócitos (anti-myelin oligodendrocyte glycoprotein, anti-MOG, em inglês). O tratamento deve ser iniciado dentro das primeiras 4 semanas dos sintomas, sendo as opções de primeira linha metilprednisolona combinada com imunoglobulina intravenosa (IGIV) ou plasmaférese. O tratamento de segunda linha inclui rituximabe e ciclofosfamida. Bortezomib e tocilizumab são opções de tratamento de terceira linha. A maioria das crises epilépticas nas EAIs são sintomáticas, e os fármacos anticrise podem ser desmamadas após a fase aguda. Em relação à encefalite antirreceptor de N-metil-D-aspartato (anti-N-methyl-D-aspartate receptor, anti-NMDAR, em inglês), os especialistas concordaram que agentes imunossupressores orais não devem ser usados. Os pacientes devem ser avaliados na fase aguda e pós-aguda mediante escalas funcionais e cognitivas, como Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Modified Rankin Scale (mRS), e Clinical Assessment Scale in Autoimmune Encephalitis (CASE). Conclusão Esta pesquisa oferece evidências tangíveis do manejo efetivo de pacientes com EAIs no sistema de saúde Brasileiro. (EAIs gliais subagudos movimento jovem prognóstico ABN (ABN SBNI, SBNI , (SBNI) Delphi 2 infantis participar LCR (LCR tissuebased tissue based assay TBA inglês cellbased cell CBA inglês. . antimyelin anti myelin glycoprotein antiMOG, antiMOG MOG, MOG anti-MOG IGIV (IGIV plasmaférese ciclofosfamida sintomáticas NmetilDaspartato N metil D aspartato antiNmethylDaspartate methyl aspartate receptor antiNMDAR, antiNMDAR NMDAR, NMDAR anti-NMDAR inglês, usados pósaguda pós cognitivas MiniMental Mini Mental MMSE, MMSE (MMSE) MoCA, MoCA (MoCA) mRS, mRS (mRS) CASE. CASE (CASE) Brasileiro (SBNI (MMSE (MoCA (mRS (CASE

Abstract Background Autoimmune encephalitis (AIE) is a group of inflammatory diseases characterized by the presence of antibodies against neuronal and glial antigens, leading to subacute psychiatric symptoms, memory complaints, and movement disorders. The patients are predominantly young, and delays in treatment are associated with worse prognosis. Objective With the support of the Brazilian Academy of Neurology (Academia Brasileira de Neurologia, ABN) and the Brazilian Society of Child Neurology (Sociedade Brasileira de Neurologia Infantil, SBNI), a consensus on the diagnosis and treatment of AIE in Brazil was developed using the Delphi method. Methods A total of 25 panelists, including adult and child neurologists, participated in the study. Results The panelists agreed that patients fulfilling criteria for possible AIE should be screened for antineuronal antibodies in the serum and cerebrospinal fluid (CSF) using the tissue-based assay (TBA) and cell-based assay (CBA) techniques. Children should also be screened for anti-myelin oligodendrocyte glucoprotein antibodies (anti-MOG). Treatment should be started within the first 4 weeks of symptoms. The first-line option is methylprednisolone plus intravenous immunoglobulin (IVIG) or plasmapheresis, the second-line includes rituximab and/or cyclophosphamide, while third-line treatment options are bortezomib and tocilizumab. Most seizures in AIE are symptomatic, and antiseizure medications may be weaned after the acute stage. In anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis, the panelists have agreed that oral immunosuppressant agents should not be used. Patients should be evaluated at the acute and postacute stages using functional and cognitive scales, such as the Mini-Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), the Modified Rankin Scale (mRS), and the Clinical Assessment Scale in Autoimmune Encephalitis (CASE). Conclusion The present study provides tangible evidence for the effective management of AIE patients within the Brazilian healthcare system. (AIE antigens symptoms complaints disorders young prognosis Academia ABN Sociedade Infantil SBNI, SBNI , SBNI) method 2 neurologists CSF (CSF tissuebased tissue based TBA (TBA cellbased cell CBA (CBA techniques antimyelin anti myelin antiMOG. antiMOG MOG . (anti-MOG) firstline line IVIG (IVIG plasmapheresis secondline second andor cyclophosphamide thirdline third tocilizumab symptomatic stage antiNmethylDaspartate N methyl D aspartate antiNMDAR NMDAR (anti-NMDAR used scales MiniMental Mini Mental MMSE, MMSE (MMSE) MoCA, MoCA (MoCA) mRS, mRS (mRS) CASE. CASE (CASE) system (anti-MOG (MMSE (MoCA (mRS (CASE

https://doi.org/10.1055/s-0044-1788586

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