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RESUMO Objetivo: Atualizar as recomendações para embasar as decisões para o tratamento farmacológico de pacientes hospitalizados com COVID-19 no Brasil. Métodos: A elaboração desta diretriz foi feita por especialistas, incluindo representantes do Ministério da Saúde e metodologistas. O método utilizado para o desenvolvimento rápido de diretrizes baseou-se na adoção e/ou adaptação de diretrizes internacionais existentes (GRADE ADOLOPMENT) e contou com o apoio da plataforma e-COVID-19 RecMap. A qualidade das evidências e a elaboração das recomendações seguiram o método GRADE. Resultados: Chegaram-se a 21 recomendações, incluindo recomendações fortes quanto ao uso de corticosteroides em pacientes em uso de oxigênio suplementar e recomendações condicionais para o uso de tocilizumabe e baricitinibe, em pacientes com oxigênio suplementar ou ventilação não invasiva, e de anticoagulantes, para prevenção de tromboembolismo. Devido à suspensão da autorização de uso, não foi possível fazer recomendações para o tratamento com casirivimabe + imdevimabe. Foram feitas recomendações fortes contra o uso de azitromicina em pacientes sem suspeita de infecção bacteriana, hidroxicloroquina, plasma convalescente, colchicina e lopinavir + ritonavir, além de recomendações condicionais contra o uso de ivermectina e rendesivir. Conclusão: Foram criadas novas recomendações para o tratamento de pacientes hospitalizados com COVID-19, como as recomendações de tocilizumabe e baricitinibe. Ainda são recomendados corticosteroides e profilaxia contra tromboembolismo, esta em caráter condicional. Vários medicamentos foram considerados ineficazes e não devem ser usados, no intuito de proporcionar o melhor tratamento segundo os princípios da medicina baseada em evidências e promover a economia de recursos. Objetivo COVID19 COVID 19 COVID-1 Brasil Métodos especialistas metodologistas baseouse baseou se eou GRADE ADOLOPMENT eCOVID19 eCOVID e-COVID-1 RecMap Resultados Chegaramse Chegaram 2 baricitinibe invasiva anticoagulantes tromboembolismo imdevimabe bacteriana hidroxicloroquina convalescente ritonavir rendesivir Conclusão COVID19, 19, condicional usados recursos COVID1 1 COVID- eCOVID1 e-COVID- e-COVID

ABSTRACT Objective: To update the recommendations to support decisions regarding the pharmacological treatment of patients hospitalized with COVID-19 in Brazil. Methods: Experts, including representatives of the Ministry of Health and methodologists, created this guideline. The method used for the rapid development of guidelines was based on the adoption and/or adaptation of existing international guidelines (GRADE ADOLOPMENT) and supported by the e-COVID-19 RecMap platform. The quality of the evidence and the preparation of the recommendations followed the GRADE method. Results: Twenty-one recommendations were generated, including strong recommendations for the use of corticosteroids in patients using supplemental oxygen and conditional recommendations for the use of tocilizumab and baricitinib for patients on supplemental oxygen or on noninvasive ventilation and anticoagulants to prevent thromboembolism. Due to suspension of use authorization, it was not possible to make recommendations regarding the use of casirivimab + imdevimab. Strong recommendations against the use of azithromycin in patients without suspected bacterial infection, hydroxychloroquine, convalescent plasma, colchicine, and lopinavir + ritonavir and conditional recommendations against the use of ivermectin and remdesivir were made. Conclusion: New recommendations for the treatment of hospitalized patients with COVID-19 were generated, such as those for tocilizumab and baricitinib. Corticosteroids and prophylaxis for thromboembolism are still recommended, the latter with conditional recommendation. Several drugs were considered ineffective and should not be used to provide the best treatment according to the principles of evidence-based medicine and to promote resource economy. Objective COVID19 COVID 19 COVID-1 Brazil Methods Experts methodologists guideline andor ADOLOPMENT eCOVID19 eCOVID e e-COVID-1 platform Results Twentyone Twenty one generated authorization imdevimab infection hydroxychloroquine plasma colchicine made Conclusion recommended recommendation evidencebased economy COVID1 1 COVID- eCOVID1 e-COVID- e-COVID

https://doi.org/10.5935/2965-2774.20230136-en

Brazilian guidelines for the treatment of outpatients with suspected or confirmed COVID-19. A joint guideline of the Brazilian Association of Emergency Medicine (ABRAMEDE), Brazilian Medical Association (AMB), Brazilian Society of Angiology and Vascular Surgery (SBACV), Brazilian Society of Geriatrics and Gerontology (SBGG), Brazilian Society of Infectious Diseases (SBI), Brazilian Society of Family and Community Medicine (SBFMC), and Brazilian Thoracic Society (SBPT)
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Falavigna, Maicon

; Belli, Karlyse Claudino

; Barbosa, Alexandre Naime

; Zavascki, Alexandre Prehn

; Nastri, Ana Catharina de Seixas Santos

; Santana, Christiane Machado

; Stein, Cinara

; Gräf, Débora Dalmas

; Cadegiani, Flavio Adsuara

; Guimarães, Hélio Penna

; Monteiro, José Tadeu

; Ferreira, Juliana Carvalho

; de Azevedo, Luciano Cesar Pontes

; Magri, Marcelo Mihailenko Chaves

; Sobreira, Marcone Lima

; Dias, Maria Beatriz Gandra de Souza

; de Oliveira, Maura Salaroli

; Corradi, Mirian de Freitas Dal Ben

; Rosa, Regis

; Heinzelmann, Ricardo Souza

; da Silva, Rosemeri Maurici

; Belfort Junior, Rubens

; Cimerman, Sergio

; Colpani, Verônica

; Veiga, Viviane Cordeiro

; de Carvalho, Carlos Roberto Ribeiro

Brazilian Journal of Infectious Diseases

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2022, Volume 26 N. 2 elocation 102347

Abstract: En | Text: En | PDF: En

ABSTRACT Background Several therapies have been used or proposed for the treatment of COVID-19, although their effectiveness and safety have not been properly evaluated. The purpose of this document is to provide recommendations to support decisions about the drug treatment of outpatients with COVID-19 in Brazil. Methods A panel consisting of experts from different clinical fields, representatives of the Brazilian Ministry of Health, and methodologists (37 members in total) was responsible for preparing these guidelines. A rapid guideline development method was used, based on the adoption and/or adaptation of recommendations from existing international guidelines combined with additional structured searches for primary studies and new recommendations whenever necessary (GRADE-ADOLOPMENT). The rating of quality of evidence and the drafting of recommendations followed the GRADE method. Results Ten technologies were evaluated, and 10 recommendations were prepared. Recommendations were made against the use of anticoagulants, azithromycin, budesonide, colchicine, corticosteroids, hydroxychloroquine/chloroquine alone or combined with azithromycin, ivermectin, nitazoxanide, and convalescent plasma. It was not possible to make a recommendation regarding the use of monoclonal antibodies in outpatients, as their benefit is uncertain and their cost is high, with limitations of availability and implementation. Conclusion To date, few therapies have demonstrated effectiveness in the treatment of outpatients with COVID-19. Recommendations are restricted to what should not be used, in order to provide the best treatment according to the principles of evidence-based medicine and to promote resource savings by aboiding ineffective treatments.

https://doi.org/10.1016/j.bjid.2022.102347

Diversidad de trips (Insecta: Thysanoptera: Thripidae) asociados al cultivo de gladiolo en México
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Quiñones-Valdez, Rosalba

; Sánchez-Pale, Jesús Ricardo

; Castañeda-Vildozola, Álvaro

; Mejorada-Gómez, Elizabeth

; Johansen-Naime, Roberto

Revista Colombiana de Entomología

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jun 2020, Volume 46 N. 1 elocation e8607

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen El gladiolo es una planta ornamental de corte con alta demanda durante todo el año en México, generando una fuerte actividad económica y social. Los trips son la principal plaga que lo afecta, y que mayor control requiere, pero se desconoce la identidad de las especies que lo dañan. El presente estudio tuvo la finalidad de conocer la diversidad de especies de trips asociadas al cultivo de gladiolo en dos regiones productoras del estado de México. Se establecieron dos parcelas: la parcela uno ubicada en Ixtlahuaca, de la región norte, caracterizada por un manejo poco intensivo; en tanto que la parcela dos estuvo en Villa Guerrero, de la región sureste, caracterizada por un manejo intensivo y considerada la principal región productora de ornamentales. Se utilizaron 100 espigas florales por parcela para capturar los trips al final del ciclo de cultivo. Los resultados indicaron la presencia de dos géneros, cinco especies fitófagas presentes en la región norte, y un género depredador; mientras que en la región sureste se presentaron los dos mismos géneros pero con la presencia de 12 especies, una de las cuales es nueva para México. Thrips simplex fue la especie más abundante en las dos parcelas evaluadas.

Abstract Gladiolus is a cut flower with the highest year-round demand in Mexico, generating strong economic and social activity. Thrips are the pest that most affects gladiolus and require the most control, but which species cause damage are still unknown. This study aimed to characterize the diversity of thrip species associated with gladiolus cultivation in two production regions of Mexico State. Two plots were established: one in Ixtlahuaca, in the northern part of the state, characterized by less intensive management, and one in Villa Guerrero, in the southeastern part of the state, characterized by intensive management and considered the main production region for ornamentals. Thrips were captured from 100 floral spikes per plot at the end of the cultivation cycle. Results showed the presence of two genera and five species of phytophagous thrips, as well as one predatory thrip genus, in the northern region, while in the southeast region the same two genera were represented but with 12 species, one of which is new for Mexico. Thrips simplex was the most abundant species in both plots evaluated.

https://doi.org/10.25100/socolen.v46i1.8607 384 downloads

Comportamiento espacial y temporal de Thrips simplex Morison (Thysanoptera: Thripidae) en la región norte del Estado de México
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Quiñones-Valdez, Rosalba

; Sánchez-Pale, Jesús Ricardo

; Castañeda-Vildozola, Álvaro

; Franco Mora, Omar

; Johansen-Naime, Roberto

; Mejorada-Gómez, Elizabeth

Acta zoológica mexicana

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2020, Volume 36 elocation e3611161

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT The gladiolus is the most widely cultivated ornamental in Mexico. Its flowers are commercialized year-round, though demand is particularly high on specific dates, such as Father's Day and Day of the Dead. Principal phytosanitary problems include trips, whitefly, rust, and drying. Trips are considered the main insect pest due to the extensive damage they cause to flower quality, leading to economic loss in addition to the already high investment in their control. The objective of this work was to determine the spatial and temporal behavior of Thrips simplex (Morison, 1930) in commercial plots of roja borrega variety gladiolus. Thrip density was evaluated using 121 yellow-colored traps during three phenological stages in each of the two plots evaluated, during the winter-spring and summer-fall growing cycles of 2013 and 2014. Traps were georeferenced and placed according on a 10m x 10m grid in each plot. A geostatistical analysis was carried out to obtain the experimental semivariograms for adjusted theoretical models and generate density maps. Thrips simplex was found to be present throughout all stages of the gladiolus phenological cycle in both years of the study, and showed an aggregated spatial and temporal behavior, adjusted to different spatial patterns. Densities varied little among sampling dates, though the location and dispersal of aggregation centers differed among the three phenological stages in each plot, when visualized using the maps generated in the two production cycles evaluated.

RESUMEN El gladiolo es la ornamental de mayor superficie sembrada en México, su flor se comercializa durante todo el año, aunque en fechas específicas como el día del padre y el día de muertos presenta fuerte demanda. Sus principales problemas fitosanitarios son trips, mosquita blanca, roya y secamiento. Los trips son considerados la plaga más limitante por los fuertes daños que ocasionan a la calidad de la flor, generan pérdidas económicas aunadas a la fuerte inversión que implica su control. El objetivo del trabajo fue determinar el comportamiento espacial y temporal de Thrips simplex (Morison, 1930) en parcelas comerciales de gladiolo de la variedad roja borrega. Se evaluó su densidad en 121 trampas de color amarillo, durante tres etapas fenológicas, en cada una de las dos parcelas evaluadas durante los ciclos invierno-verano y verano-otoño de los años 2013-2014. Las trampas fueron georeferenciadas, se colocaron en forma de una malla de 10x10 m en cada parcela. Se realizó el análisis geoestadístico para obtener los semivariogramas a modelos ajustados y validados para elaborar mapas de densidad. Thrips simplex mostró un comportamiento espacial de tipo agregado, ajustándose a diferentes patrones espaciales y temporales. Las densidades presentaron poca variación entre las diferentes fechas de muestreo, aunque la ubicación y dispersión de los centros de agregación fue diferente en las tres etapas fenológicas para la misma parcela, visualizándose con los mapas generados en los dos ciclos de producción evaluados.

https://doi.org/10.21829/azm.2020.3611161 632 downloads

Diversidad de tisanópteros en crisantemo [Dendranthema grandiflorum (Ramat.) Kitamura] var. Harman en Texcoco, estado de México
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Loera-Alvarado, Esperanza

; Ortega-Arenas, Laura Delia

; Johansen-Naime, Roberto Miguel

; González-Hernández, Héctor

; Lomelí-Flores, Refugio

; Santillán-Galicia, Ma. Teresa

; Ochoa-Martínez, Daniel Leobardo

Acta zoológica mexicana

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apr 2017, Volume 33 N. 1 Pages 1 - 8

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract: In order to determine the diversity of thrips species associated with Chrysanthemum [Dendranthema grandiflorum (Ramat.) Kitamura] var. Harman, at four locations in the municipality of Texcoco, State of Mexico, larvae and adults were collected biweekly in the periods from March to June and August to November 2011. The collected individuals were subjected to clarification techniques and mounted for identification. Seventeen species of thrips were identified, included in the genera Frankliniella with 13 species and Anaphothrips, Chrirothrips, Neohydatothrips and Leptothrips with one species each. Most abundant species were F. occidentalis and F. brunnescens (88.6%). The diversity and abundance of thrips was similar in the four localities. The ecological relevance of our findings is discussed.

Resumen: Con el objetivo de estimar la diversidad de especies de tisanópteros asociados al cultivo de crisantemo [Dendranthema grandiflorum (Ramat.) Kitamura] var. Harman en cuatro localidades en el municipio de Texcoco, Estado de México, se realizaron recolectas quincenales de larvas y adultos, en los periodos de marzo a junio y agosto a noviembre de 2011. Los individuos recolectados se sometieron a técnicas de aclaración y montaje para su identificación. Se identificaron 17 especies de trips, incluidas en los géneros Frankliniella con 13 especies; Neohydatothrips, Anaphothrips, Chrirothrips y Leptothrips con una especie cada uno. Las especies más abundantes fueron F. occidentalis y F. brunnescens (88.6%). La diversidad y abundancia de tisanópteros fue similar en las cuatro localidades estudiadas. Se discute la relevancia ecológica de nuestros hallazgos.

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El grupo Frankliniella Tritici en la región de América Central, El Caribe y México (Terebrantia: Thripidae) y descripción de una nueva especie para México, Frankliniella oaxacensis
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Retana-Salazar, Axel P.

; Ruiz de la Cruz, Javier

; Rodríguez-Arrieta, J. Alexander

; Vásquez-López, Alfonso

; Johansen-Naime, Roberto

; Bernal-Prado, Nelson Eulises

Acta zoológica mexicana

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2014, Volume 30 N. 1 Pages 41 - 60

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Frankliniella is the most diversity thrips in the tropics and it presents a high taxonomic complexity. The tritici group defined in this work has been based on the mostly functional characters to define species close to Frankliniella tritici and Frankliniella cubensis. Variations on the ring antennal segment III are clear in some species of cephalica group; more over this modification take place as shape of a truncated cone in species such as Frankliniella Standleyana and Frankliniella pineticola. This contributionis a brief synopsis of the species groups within Frankliniella and a revision of the species of this genus including species from Central America and Mexico.

El género Frankliniella es de gran diversidad en los trópicosy de alta complejidad taxonómica. El grupo tritici se ha definido en este trabajo con base en los caracteres mayormente funcionales para definir el grupo de especies más restringido cercanas a las especies Frankliniella tritici y Frankliniella cubensis. Las variaciones del collar en el segmento antenal III se manifiestan en algunas especies de la serie cephalica y en algunas especies como Frankliniella Standleyana y Frankliniella pineticola es evidente una modificación en forma de cono truncado. Este trabajo presenta una breve sinopsis y revisión de los grupos de especies dentro de Frankliniella incluyendo especies de las regiones del Caribe, América Central y México.

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Responsabilidade civil do Estado por omissão estatal
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Hupffer, Haide Maria

; Naime, Roberto

; Adolfo, Luiz Gonzaga Silva

; Corrêa, Iose Luciane Machado

Revista Direito GV

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jun 2012, Volume 8 N. 1 Pages 109 - 129

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Constituição Federal de 1988 é um divisor de águas ao assumir-se como Constituição Ambiental, provocando uma ruptura em relação ao conceito de responsabilidade civil. Partindo de uma abordagem qualitativa, dialética e jurisprudencial, este artigo analisa o Princípio Responsabilidade desenvolvido por hans jonas e realiza um diálogo com o instituto da responsabilidade civil ambiental, identificando, com apoio na legislação constitucional e infraconstitucional, as controvérsias doutrinárias acerca da natureza da responsabilidade estatal (objetiva ou subjetiva) frente a casos de omissão da administração pública e à ocorrência de dano ambiental. Conclui-se que o Superior Tribunal de Justiça assume uma dimensão mais alargada do conceito de responsabilidade civil do Estado, demonstrando uma tendência pela responsabilidade civil objetiva com base no risco. Assim, o Brasil, salvo algumas divergências doutrinárias, adota a responsabilidade civil objetiva do Estado pela teoria do risco administrativo alicerçada no ato ilícito e na aceitação do risco.

The Federal Constitution of 1988 is a 'water divisor' since it assumes the role of Environmental Constitution, causing a rapture of the concept of civil liability. Starting from a qualitative, dialectical and jurisprudential approach, this article analyzes the Principle of Liability according to Hans Jonas in order to dialogue with the Institute of Civil Environmental Liability, identifying, with the support of the constitutional and infraconstitutional legislation, the doctrinary controversies about the nature of state liability (objective or subjective) towards cases of neglect by the public administration and the event of environmental damage. It is possible to conclude that the Higher Court of Justice assumes a larger dimension of the civil liability of the State, thus showing the tendency towards the objective civil liability based on the risk. Therefore, Brazil, regarded some doctrinary differences, adopts the objective civil liability for the State through the theory of administrative risk based on the illicit act and the acceptance of the risk.

19807 downloads

Especies de Neohydatothrips John (Thysanoptera: Thripidae) de Nayarit, México, y descripción de una especie nueva
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VALENZUELA-GARCÍA, Rita D.

; RETANA-SALAZAR, Axel P.

; JOHANSEN-NAIME, Roberto M.

; GARCÍA-MARTÍNEZ, Oswaldo

; GALLEGOS-MORALES, Gabriel

; CARVAJAL-CAZOLA, Carlos

Acta zoológica mexicana

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apr 2012, Volume 28 N. 1 Pages 49 - 55

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

The species of Neohydatothrips from the state of Nayarit, associated to different crops are presented. Also a new species similar to N. mirandai Johansen is described which differs from the rest by having a yellow pronotum.

Se dan a conocer las especies de Neohydatothrips del estado de Nayarit, asociadas a diferentes cultivos, y se describe una nueva especie cercana a N. mirandai Johansen, la cual se diferencia por tener el pronoto de color amarillo.

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Especies depredadoras de trips (Thysanoptera) asociadas a huertas de aguacate en Nayarit, México
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CAMBERO-CAMPOS, Jhonathan

; JOHANSEN-NAIME, Roberto

; GARCÍA-MARTÍNEZ, Oswaldo

; CANTU-SIFUENTES, Mario

; CERNA-CHAVEZ, Ernesto

; RETANA-SALAZAR, Axel

Acta zoológica mexicana

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apr 2011, Volume 27 N. 1 Pages 115 - 121

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

The objective of this study was to identify the predaceous thrips species associated with the avocado crop in the state of Nayarit. This research was carried out in four avocado orchards of the cultivars Hass, Choquette and Hall. Weekly samples were taken from January to December, 2008, using the knockdown and net sweeping sampling methods. A total of 294 thrips were identified as predators within 16 species. Franklinothrips vespiformis was the dominant species (21.8%) followed by Lepto-Cambero-Campos et al.: Trips depredadores en aguacate de Nayarit thrips primigenus (21.4%) and F. orizabensis (19.0%), the remaining species collected accounted for 37.8%.

El objetivo fue identificar las especies de trips depredadoras asociadas al cultivo del aguacate en el Estado de Nayarit. El trabajo se llevó a cabo en cuatro huertas de aguacate del cultivar "Hass" y una con los cultivares "Choquette" y "Hall". Se realizaron muestreos semanales de enero a diciembre de 2008, utilizando las técnicas de muestreo de derribo y redeo. Se determinaron 294 trips con hábitos depredadores, resultando 16 especies. Franklinothrips vespiformis fue la especie más representada (21.8 %), seguida de Leptothrips primigenus (21.4%), y F. orizabensis (19.0 %), las restantes especies recolectadas representaron el 37.8 %.

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10.

Susceptibilidad a insecticidas en tres poblaciones mexicanas del trips del laurel, Gynaikothrips ficorum (Marchal) (Thysanoptera: Phlaeothripidae)
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Loera-Barocio, J. Carlos De

; Lagunes-Tejeda, Ángel

; Rodríguez-Maciel, J. Concepción

; Johansen-Naime, Roberto

; Romero-Nápoles, Jesús

; Manuel-Pinto, Víctor

; Silva-Aguayo, Gonzalo

Agrociencia

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feb 2011, Volume 45 N. 1 Pages 61 - 73

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Gynaikothrips ficorum (Marchal) is a pest of the laurel tree in urban zones and insecticides are possibly used for its control, but its initial response to these products is unknown. Therefore susceptibility of various populations of this species was determined (Texcoco, Córdoba and Tlayacapan) to the insecticides permethrin, cypermethrin, diazinón, malathion, methyl oxydemeton, methyl parathion, endosulfán and methomyl. The Texcoco population was used as reference to make comparisons of the response. At 24 h of exposure, the confidence levels of the CL50 of the three populations overlapped in the insecticides cypermethrin, diazinón, malathion and methyl oxydemeton; but they did not overlap in Córdoba and Tlayacapan with Texcoco, for permethrin, methyl parathion, endosulfán and methomyl. For Córdoba and Tlayacapan with cypermethrin, the resistance proportion (RP50) was 0.88 and 0.53'; with diazinón, 0.3 and 0.29'; with malathion 1.04 and 1.02'; with methyl oxydemoton 0.74 and 7.18'; with methyl parathion 8.4 and 4.63'; with endosulfán 1.19 and 0.2', and with methomyl 0.11 and 0.53'. At 95 % mortality, only in Tlayacapan and for endosulfán (RP95=0.03), the fiducial limits did not overlap with the other two populations. The values obtained at 48 h of exposure followed the same tendencies found at 24 h. These response values correspond to a susceptible state and can be used as comparison reference.

Gynaikothrips ficorum (Marchal) es una plaga del laurel en zonas urbanas y posiblemente se usan insecticidas para su control, pero se desconoce su respuesta inicial a éstos. Por tanto, se determinó la susceptibilidad de varias poblaciones de esta especie (Texcoco, Córdoba y Tlayacapan) a los insecticidas permetrina, cipermetrina, diazinón, malatión, oxidemetón metílico, paratión metílico, endosulfán y metomil. La población Texcoco se usó como referencia para hacer comparaciones de la respuesta. A las 24 h de exposición, los límites de confianza de la CL50 de las tres poblaciones se traslaparon en los insecticidas cipermetrina, diazinón, malatión y oxidemetón metílico; pero no se traslaparon en Córdoba y Tlayacapan con Texcoco, para permetrina, paratión metílico, endosulfán y metomil. Para Córdoba y Tlayacapan con cipermetrina, la proporción de resistencia (PR50) fue 0.88 y 0.53'; con diazinón 0.3 y 0.29'; con malatión 1.04 y 1.02'; con oxidemetón metílico 0.74 y 0.9'; con permetrina 5 y 7.18'; con paratión metílico 8.4 y 4.63'; con endosulfán 1.19 y 0.2', y con metomil 0.11 y 0.53'. A nivel del 95 % de mortalidad, sólo en Tlayacapan y para endosulfán (PR95 =0.03), los límites fiduciales no se traslaparon con las otras dos poblaciones. Los valores obtenidos a las 48 h de exposición siguieron las mismas tendencias encontradas a las 24 h. Estos valores de respuesta corresponden a un estado susceptible y se podrán usar como referencia de comparación.

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You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.

For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

See below the complete list of search indexes that can be used:

Index code	Element
ti	article title
au	author
kw	article keywords
subject	subject (title words, abstract and keywords)
ab	abstract
ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

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