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Pregnancy in patients with chronic kidney disease undergoing dialysis
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Gorayeb-Polacchini, Fernanda Salomão

; Moura, Ana Flavia

; Luders, Claudio

; Moura Neto, José Andrade

; Leme, Juliana El Ghoz

; Silva, Dirceu Reis da

Brazilian Journal of Nephrology

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dec 2024, Volume 46 N. 4 elocation e20240067

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo As mulheres portadoras de doença renal crônica apresentam menor probabilidade de engravidar e são mais propensas a complicações gestacionais quando comparadas a pacientes com função renal normal, sendo, portanto, consideradas gestantes de alto risco materno e fetal. Ao longo dos anos, verificou-se aumento da incidência de gestações em pacientes em diálise e melhora do desfecho materno e fetal. Acredita-se que a otimização do atendimento obstétrico e neonatal, o ajuste do tratamento dialítico (em especial, o aumento do número de horas e da frequência semanal das sessões de diálise) e o uso de agentes estimuladores da eritropoiese têm proporcionado melhor controle metabólico, volêmico, pressórico, eletrolítico e da anemia. Este artigo de revisão tem o objetivo de analisar os desfechos gestacionais em pacientes com doença renal crônica em diálise e revisar a condução médica nefrológica nesse cenário. Pelo crescente interesse pelo tema, as recomendações clínicas para a prática assistencial têm ganhado em consistência tanto no manejo medicamentoso quanto no manuseio dialítico, aspectos que tratamos na presente revisão. normal sendo portanto fetal anos verificouse verificou se Acreditase Acredita neonatal especial metabólico volêmico pressórico anemia cenário tema

Abstract Women with chronic kidney disease are less likely to become pregnant and are more susceptible to pregnancy complications when compared to patients with normal kidney function. As a result, these are considered high-risk pregnancies, both maternal and fetal. Over the years, there has been an increase in the incidence of pregnancies in dialysis patients, and an improvement in maternal and fetal outcomes. It is believed that the optimization of obstetric and neonatal care, the adjustment of dialysis treatment (particularly the increase in the number of hours and weekly frequency of dialysis sessions), and the use of erythropoiesis-stimulating agents have provided better metabolic, volume, blood pressure, electrolyte, and anemia control. This review article aims to analyze pregnancy outcomes in chronic kidney disease patients undergoing dialysis and to review nephrological medical management in this scenario. Due to the growing interest in the subject, clinical recommendations for care practice have become more consistent in both drug and dialysis management, aspects that are addressed in this review. function result highrisk high risk years particularly sessions, sessions , sessions) erythropoiesisstimulating erythropoiesis stimulating metabolic volume pressure electrolyte control scenario subject

https://doi.org/10.1590/2175-8239-jbn-2024-0067en

Guia para a elaboração de relatórios fonoaudiológicos de crianças implantadas: opinião de especialistas implantadas
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Frederigue-Lopes, Natália Barreto

; Silva, Joice de Moura

; Souza, Flávia Custódio Pedroso de

; Ricardo, Marcela Beatriz

; Angelo, Thais Corina Said de

; Jacob, Regina Tangerino de Souza

; Moret, Adriane Lima Mortari

; Zupelari, Marina Morettin

CoDAS

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2024, Volume 36 N. 1 elocation e20220177

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo Desenvolver guia para elaboração de relatórios fonoaudiológicos de crianças implantadas para serem compartilhados entre fonoaudiólogos dos serviços de implante coclear (IC) e reabilitadores. Método O método Delphi foi utilizado para selecionar os itens relevantes e fundamentais que deveriam constar nas duas versões propostas para compor o guia: Guia 1 - Relatórios fonoaudiológicos fornecidos pelo serviço de IC aos reabilitadores, e Guia 2 - Relatórios fonoaudiológicos fornecidos pelos reabilitadores aos serviços de IC. Vinte e um fonoaudiólogos especialistas e com experiência na área de implante coclear e de reabilitação auditiva participaram da discussão e do julgamento dos itens durante as rodadas de seleção. Considerou-se consenso quando o item obteve a concordância igual ou superior a 80% entre os participantes, sendo selecionados para comporem os dois guias. Resultados Após as duas rodadas, 21 itens do Guia 1 obtiveram consenso entre os terapeutas, ou seja, mais de 80% deles concordaram que estes itens deveriam estar presentes no relatório enviado pelo serviço de IC. Para o Guia 2, 22 itens analisados pelos fonoaudiólogos atuantes em serviços de IC setor pós-operatório, foram selecionados na segunda rodada. Conclusão A partir da análise das duas rodadas, foi desenvolvido o “Guia para a elaboração de relatórios fonoaudiológicos: intersecção entre serviço de IC e reabilitadores”. Este material pode ser aplicado na rotina de acompanhamento de crianças implantadas, padronizando as informações compartilhadas sobre o dispositivo eletrônico, resultados de avaliações, monitoramento dos resultados e processo terapêutico dessa população. (IC seleção Considerouse Considerou se 80 participantes guias terapeutas seja pósoperatório, pósoperatório pós operatório, operatório pós-operatório rodada . reabilitadores” eletrônico avaliações população 8

ABSTRACT Purpose To develop a guide for the preparation of speech-language reports of implanted children to be shared among speech-language pathologists of cochlear implant (CI) services and rehabilitation professionals. Methods The Delphi method was used to select the relevant and fundamental items that should be included in the two versions proposed for the guide: Guide 1 - Speech-language reports provided by the CI services to rehabilitators, and Guide 2 - Speech-language reports provided by the rehabilitators to CI services. Twenty-one speech therapists specialized and with experience in cochlear implants and auditory rehabilitation participated in the discussion and judgment of the items during the selection rounds. Consensus was considered when the item reached agreement equal to or greater than 80% among participants, being selected to compose the two guides. Results After the two rounds, 21 items from Guide 1 reached consensus among therapists, that is, more than 80% of them agreed that these items should be present in the report sent by the CI service. For Guide 2, 22 items analyzed by speech therapists working in CI services in the postoperative sector were selected in the second round. Conclusion Based on the analysis of the two rounds, the “Guide for the preparation of speech-language pathology reports: intersection between CI service and rehabilitators” was developed. This material can be applied in the follow-up of implanted children, standardizing the information shared about the electronic device, evaluation results, monitoring of results and therapeutic process of this population. speechlanguage language (CI professionals Speechlanguage Speech Twentyone Twenty one rounds 80 participants guides is round developed followup follow up device population 8

https://doi.org/10.1590/2317-1782/20232022177pt

Hyperventilation worsens inflammatory lung injury in spontaneously breathing rats
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Ferreira, Juliana Dias Nascimento

; Reboredo, Maycon Moura

; Costa, Eduardo Leite Vieira

; Fonseca, Lídia Maria Carneiro da

; Retamal, Jaime

; Santos, Fabrício Júnio Mendes

; Paoli, Flavia de

; Fonseca, Adenilson de Souza da

; Lucinda, Leda Marília Fonseca

; Pinheiro, Bruno Valle

Jornal Brasileiro de Pneumologia

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2024, Volume 50 N. 6 elocation e20240269

Abstract: En | Text: En | PDF: En

ABSTRACT Objectives: Here, we investigated the effects of hyperventilation on acute lung injury (ALI) in spontaneously breathing rats. Methods: Wistar rats were randomized to receive either intraperitoneal lipopolysaccharides (LPS) or saline, and intravenous infusion of NH4Cl (to induce metabolic acidosis and hyperventilation) or saline. Four groups were established: control-control (C-C), control-hyperventilation (C-HV), LPS-control (LPS-C), and LPS-hyperventilation (LPS-HV). Venous blood gases were collected before and after NH4Cl infusion and analyzed to confirm the presence of metabolic acidosis and hyperventilation. After euthanasia, lung injury was assessed using the ALI score, morphometric quantification of perivascular edema, neutrophil counts in the bronchoalveolar lavage, and mRNA expression of biological markers in the lung tissue. Results: Hyperventilation induced inflammatory lung injury in previously healthy lungs and exacerbated injuries previously induced by LPS (ALI score: C-C=0.14 [IQR 0.12; 0.14]; C-HV=0.36 [IQR 0.31; 0.37]; LPS-C=0.51 [IQR 0.50; 0.54]; LPS-HV=0.58 [IQR 0.56; 0.62]; p<0.01). Perivascular edema, neutrophil counts in bronchoalveolar lavage, and amphiregulin mRNA expression were higher in the LPS-HV group compared to the control group. Conclusions: Hyperventilation increased inflammatory injury in rats with ALI during spontaneous ventilation. These results suggest that the impact of vigorous spontaneous breathing efforts on worsening inflammatory lung injury warrants further investigation. Objectives Here Methods (LPS saline NHCl NH Cl established controlcontrol CC, CC C , (C-C) controlhyperventilation CHV, CHV HV (C-HV) LPScontrol LPSC, LPSC (LPS-C) LPShyperventilation LPSHV. LPSHV . (LPS-HV) euthanasia score edema lavage tissue Results CC=0.14 CC014 C=0.14 0 14 C-C=0.1 IQR 0.12 012 12 0.14 014 0.14] CHV=0.36 CHV036 HV=0.36 36 C-HV=0.3 0.31 031 31 0.37 037 37 0.37] LPSC=0.51 LPSC051 C=0.51 51 LPS-C=0.5 0.50 050 50 0.54 054 54 0.54] LPSHV=0.58 LPSHV058 HV=0.58 58 LPS-HV=0.5 0.56 056 56 0.62 062 62 0.62] p<0.01. p001 p p<0.01 01 p<0.01) Conclusions ventilation investigation (C-C (C-HV (LPS-C (LPS-HV CC=0.1 CC01 C014 C=0.1 1 C-C=0. 0.1 CHV=0.3 CHV03 HV036 HV=0.3 3 C-HV=0. 0.3 03 LPSC=0.5 LPSC05 C051 C=0.5 5 LPS-C=0. 0.5 05 LPSHV=0.5 LPSHV05 HV058 HV=0.5 LPS-HV=0. 0.6 06 6 p00 p<0.0 CC=0. CC0 C01 C=0. C-C=0 0. CHV=0. CHV0 HV03 HV=0. C-HV=0 LPSC=0. LPSC0 C05 LPS-C=0 LPSHV=0. LPSHV0 HV05 LPS-HV=0 p0 p<0. CC=0 C0 C=0 C-C= CHV=0 HV0 HV=0 C-HV= LPSC=0 LPS-C= LPSHV=0 LPS-HV= p<0 CC= C= C-C CHV= HV= C-HV LPSC= LPS-C LPSHV= p<

https://doi.org/10.36416/1806-3756/e20240269

Association between chronic health conditions and severe acute respiratory syndrome in pregnant women: an exploratory study women
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Lira Neto, José Cláudio Garcia

; Araújo, Márcio Flávio Moura de

; Monteiro, Flavia Paula Magalhães

; Freitas, Roberto Wagner Júnior Freire de

; Teixeira, Carla Regina de Sousa

; Santos, Floriacy Stabnow

; Costa, Ana Cristina Pereira de Jesus

; Santos Neto, Marcelino

; Pascoal, Lívia Maia

Revista da Escola de Enfermagem da USP

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2024, Volume 58 elocation e20230336

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: Analisar a associação entre condições crônicas de saúde e a síndrome respiratória aguda grave em gestantes. Método: Estudo retrospectivo, exploratório realizado com 1.152 gestantes de todos os 27 estados do Brasil que procuraram tratamento hospitalar e foram diagnosticadas com síndrome respiratória aguda grave entre 2020 e 2022. Foram utilizados dados públicos do Sistema de Informação de Vigilância Epidemiológica da Gripe (SIVEP-Gripe) do Ministério da Saúde do Brasil. Realizamos testes não paramétricos para a interpretação dos dados. Resultados: A taxa de mortalidade de gestantes por síndrome respiratória aguda grave no Brasil foi de 7%. A síndrome respiratória aguda grave estava estatisticamente associada à presença prévia de diabetes (p = 0,023), doença neurológica (p = 0,001) e uso de drogas (p = 0,001). A investigação epidemiológica dos casos de síndrome respiratória demorou mais tempo em gestantes negras (p = 0,012), não vacinadas (p < 0,001) e residentes na região norte e sul do país (p = 0,011). Conclusão: A síndrome respiratória aguda grave foi mais comum em gestantes com diabetes, doença neurológica e que faziam uso de drogas. Todavia, essas condições não levaram ao aumento no número de mortes. Objetivo Método retrospectivo 1152 1 152 1.15 2 202 2022 SIVEPGripe SIVEP (SIVEP-Gripe Resultados 7 7% p 0,023, 0023 0,023 , 0 023 0,023) 0,001 0001 001 0,001. . 0,012, 0012 0,012 012 0,012) 0,011. 0011 0,011 011 0,011) Conclusão Todavia mortes 115 15 1.1 20 002 0,02 02 0,00 000 00 0,01 01 11 1. 0,0 0,

ABSTRACT Objective: To analyze the association between chronic health conditions and severe acute respiratory syndrome in pregnant women. Method: Retrospective, exploratory study conducted with 1,152 pregnant women from all 27 states of Brazil who sought hospital treatment and were diagnosed with severe acute respiratory syndrome between 2020 and 2022. Public data from the Influenza Epidemiological Surveillance Information System (SIVEP-Gripe) of the Brazilian Ministry of Health were used. Nonparametric tests were performed in data interpretation. Results: The mortality rate of pregnant women due to severe acute respiratory syndrome in Brazil was 7%. Severe acute respiratory syndrome was statistically associated with the previous presence of diabetes (p = 0.023), neurological disease (p = 0.001), and drug use (p = 0.001). The epidemiological investigation of respiratory syndrome cases took longer in Black pregnant women (p = 0.012), unvaccinated women (p < 0.001) and women living in the north and south of the country (p = 0.011). Conclusion: Severe acute respiratory syndrome was more common in pregnant women with diabetes, neurological disease and drug users. However, these conditions did not lead to an increase in the number of deaths. Objective Method Retrospective 1152 1 152 1,15 2 202 2022 SIVEPGripe SIVEP Gripe (SIVEP-Gripe used interpretation Results 7 7% p 0.023, 0023 0.023 , 0 023 0.023) 0.001, 0001 0.001 001 0.001. . 0.012, 0012 0.012 012 0.012) 0.011. 0011 0.011 011 0.011) Conclusion users However deaths 115 15 1,1 20 002 0.02 02 000 0.00 00 0.01 01 11 1, 0.0 0.

RESUMEN Objetivo: Analizar la asociación entre condiciones crónicas de salud y síndrome respiratorio agudo severo en mujeres embarazadas. Método: Estudio exploratorio retrospectivo realizado con 1.152 mujeres embarazadas de los 27 estados de Brasil que buscaron tratamiento hospitalario y fueron diagnosticadas con síndrome respiratorio agudo severo entre 2020 y 2022. Se utilizaron datos públicos del Sistema de Información de Vigilancia Epidemiológica de la Influenza (SIVEP-Gripe) del Ministerio de Salud de Brasil. Se realizaron pruebas no paramétricas en la interpretación de los datos. Resultados: La tasa de mortalidad de mujeres embarazadas por síndrome respiratorio agudo severo en Brasil fue del 7%. El síndrome respiratorio agudo severo se asoció estadísticamente con la presencia previa de diabetes (p = 0,023), enfermedad neurológica (p = 0,001) y uso de drogas (p = 0,001). La investigación epidemiológica de los casos de síndrome respiratorio agudo severo fue más prolongada en las embarazadas de raza negra (p = 0,012), las no vacunadas (p < 0,001) y las residentes en el norte y sur del país (p = 0,011). Conclusión: El síndrome respiratorio agudo severo fue más frecuente en las embarazadas con diabetes, enfermedades neurológicas y usuarias de drogas. Sin embargo, estas condiciones no provocaron un aumento en el número de muertes. Objetivo Método 1152 1 152 1.15 2 202 2022 SIVEPGripe SIVEP Gripe (SIVEP-Gripe Resultados 7 7% p 0,023, 0023 0,023 , 0 023 0,023) 0,001 0001 001 0,001. . 0,012, 0012 0,012 012 0,012) 0,011. 0011 0,011 011 0,011) Conclusión embargo muertes 115 15 1.1 20 002 0,02 02 0,00 000 00 0,01 01 11 1. 0,0 0,

https://doi.org/10.1590/1980-220x-reeusp-2023-0336en

O que pode Bakhtin falar sobre os bebês: a vida coletiva em creche na perspectiva da filosofia da linguagem bebês
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Barboza, Georgete de Moura

; Motta, Flávia Miller Naethe

Revista Brasileira de Educação

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2024, Volume 29 elocation e290080

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Este artigo coloca em cena a ação de bebês num contexto de vida coletiva. À luz da filosofia da linguagem bakhtiniana, buscou-se compreender a entrada do sujeito humano no universo da linguagem, para além dos espaços privados onde as crianças muito pequenas costumam estar. A pesquisa foi realizada numa creche pública de um município do Rio de Janeiro. Como metodologia, utilizou-se do cotejo, pois, quando cotejamos um texto com outros, recuperamos parcialmente a cadeia infinita de enunciados aos quais ele responde, se contrapõe, e quais seus acordos ou desacordos. Trata-se do movimento de ir ao encontro das vozes presentes no texto para uma compreensão profunda. Apresentam-se dois eventos de campo e sua compreensão, concluindo-se pela necessidade de o adulto se colocar em diálogo com os bebês, pois cada um deles vai superando sua condição psíquica elementar em direção a formas mais avançadas por meio de relações humanizadoras, e somente outro ser humano pode humanizá-lo. coletiva bakhtiniana buscouse buscou estar Janeiro metodologia utilizouse utilizou cotejo outros responde contrapõe desacordos Tratase Trata profunda Apresentamse Apresentam concluindose concluindo humanizadoras humanizálo. humanizálo humanizá lo. lo humanizá-lo

ABSTRACT This article discusses the action of babies in a context of a collective life. In the light of the Bakhtinian philosophy of language, we sought to understand the entry of the human subject in the universe of language, in addition to the private spaces where very young children tend to be. The research was carried out in a public nursery in a municipality in the state of Rio de Janeiro. As a methodology, collation was used because when we compare a text with others, we partially recover the infinite chain of statements to which it responds, which it opposes, as well as any agreements or disagreements. It is a movement to meet the voices present in the text for a deeper understanding of them. Two field events and their understanding are presented, and we conclude with the need for adults to put themselves in a dialogue with the babies, as the latter overcome their elementary psychic condition towards more advanced forms through humanizing relationships, and only other human beings can humanize them. life language be Janeiro methodology others responds opposes disagreements them presented relationships

RESUMEN Este artículo plantea la acción de los bebés en un contexto de vida colectiva. A la luz de la Filosofía del Lenguaje Bakhtiniano, buscamos comprender la entrada del sujeto humano en el universo del lenguaje, además de los espacios privados donde suelen estar los niños muy pequeños. La investigación se llevó a cabo en una guardería pública de un municipio de Río de Janeiro. Como metodología se utilizó el cotejo porque, cuando cotejamos un texto con otros, recuperamos parcialmente la cadena infinita de enunciados a los que responde, a quienes se oponen, cuáles son sus acuerdos o desacuerdos. Es un movimiento para encontrar las voces presentes en el texto para una comprensión más profunda. Presenta dos hechos de campo y su comprensión, concluyendo por la necesidad del adulto de ponerse en diálogo con los bebés, ya que cada uno de ellos va más allá de su condición psíquica elemental hacia formas más avanzadas a través de relaciones humanizadoras y solo otro ser humano puede humanizarlo. colectiva Bakhtiniano lenguaje pequeños Janeiro porque otros responde oponen desacuerdos profunda humanizarlo

https://doi.org/10.1590/s1413-24782024290080

Safety of CoronaVac and ChAdOx1 vaccines against SARS-CoV-2 in patients with rheumatoid arthritis: data from the Brazilian multicentric study safer ChAdOx SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- arthritis SARS-CoV
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Cruz, Vitor Alves

; Guimarães, Camila

; Rêgo, Jozelia

; Machado, Ketty Lysie Libardi Lira

; Miyamoto, Samira Tatiyama

; Burian, Ana Paula Neves

; Dias, Laiza Hombre

; Pretti, Flavia Zon

; Batista, Danielle Cristina Filgueira Alves

; Mill, José Geraldo

; Oliveira, Yasmin Gurtler Pinheiro de

; Gadelha, Carolina Strauss Estevez

; Gouveia, Maria da Penha Gomes

; Moulin, Anna Carolina Simões

; Souza, Bárbara Oliveira

; Aguiar, Laura Gonçalves Rodrigues

; Vieira, Gabriel Smith Sobral

; Grillo, Luiza Lorenzoni

; Lima, Marina Deorce de

; Pasti, Laís Pizzol

; Surlo, Heitor Filipe

; Faé, Filipe

; Moulaz, Isac Ribeiro

; Macabú, Mariana de Oliveira

; Ribeiro, Priscila Dias Cardoso

; Magalhães, Vanessa de Oliveira

; Aguiar, Mariana Freitas de

; Biegelmeyer, Erika

; Peixoto;, Flávia Maria Matos Melo Campos

; Kayser, Cristiane

; Souza, Alexandre Wagner Silva de

; Castro, Charlles Heldan de Moura

; Ribeiro, Sandra Lúcia Euzébio

; Telles, Camila Maria Paiva França

; Bühring, Juliana

; Lima, Raquel Lima de

; Santos, Sérgio Henrique Oliveira Dos

; Dias, Samuel Elias Basualto

; Melo, Natália Seixas de

; Sanches, Rosely Holanda da Silva

; Boechat, Antonio Luiz

; Sartori, Natália Sarzi

; Hax, Vanessa

; Dória, Lucas Denardi

; Rezende, Rodrigo Poubel Vieira de

; Baptista, Katia Lino

; Fortes, Natália Rodrigues Querido

; Melo, Ana Karla Guedes de

; Melo, Tâmara Santos

; Vieira, Rejane Maria Rodrigues de Abreu

; Vieira, Adah Sophia Rodrigues

; Kakehasi, Adriana Maria

; Tavares, Anna Carolina Faria Moreira Gomes

; Landa, Aline Teixeira de

; Costa, Pollyana Vitoria Thomaz da

; Azevedo, Valderilio Feijó

; Martins-Filho, Olindo Assis

; Peruhype-Magalhães, Vanessa

; Pinheiro, Marcelo de Medeiros

; Monticielo, Odirlei André

; Reis-neto, Edgard Torres Dos

; Ferreira, Gilda Aparecida

; Souza, Viviane Angelina de

; Teixeira-Carvalho, Andréa

; Xavier, Ricardo Machado

; Sato, Emilia Inoue

; Valim, Valeria

; Pileggi, Gecilmara Salviato

; Silva, Nilzio Antonio da

Advances in Rheumatology

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2024, Volume 64 elocation 58

Abstract: En | Text: En | PDF: En

Abstract Background Patients with immune-mediated rheumatic diseases (IMRDs) have been prioritized for COVID-19 vaccination to mitigate the infection severity risks. Patients with rheumatoid arthritis (RA) are at a high risk of severe COVID-19 outcomes, especially those under immunosuppression or with associated comorbidities. However, few studies have assessed the safety of the COVID-19 vaccine in patients with RA. Objective To evaluate the safety of vaccines against SARS-CoV-2 in patients with RA. Methods This data are from the study “Safety and Efficacy on COVID-19 Vaccine in Rheumatic Diseases,” a Brazilian multicentric prospective phase IV study to evaluate COVID-19 vaccine in IMRDs in Brazil. Adverse events (AEs) in patients with RA of all centers were assessed after two doses of ChAdOx1 (Oxford/AstraZeneca) or CoronaVac (Sinovac/Butantan). Stratification of postvaccination AEs was performed using a diary, filled out daily and returned at the end of 28 days for each dose. Results A total of 188 patients with RA were include, 90% female. CoronaVac was used in 109 patients and ChAdOx1 in 79. Only mild AEs were observed, mainly after the first dose. The most common AEs after the first dose were pain at the injection (46,7%), headache (39,4%), arthralgia (39,4%), myalgia (30,5%) and fatigue (26,6%), and ChAdOx1 had a higher frequency of pain at the injection (66% vs 32 %, p < 0.001) arthralgia (62% vs 22%, p < 0.001) and myalgia (45% vs 20%, p < 0.001) compared to CoronaVac. The more common AEs after the second dose were pain at the injection (37%), arthralgia (31%), myalgia (23%), headache (21%) and fatigue (18%). Arthralgia (41,4% vs 25%, p = 0.02) and pain at injection (51,4% vs 27%, p = 0.001) were more common with ChAdOx1. No serious AEs were related. With Regard to RA activity level, no significant difference was observed between the three time periods for both COVID-19 vaccines. Conclusion In the comparison between the two immunizers in patients with RA, local reactions and musculoskeletal symptoms were more frequent with ChAdOx1 than with CoronaVac, especially after the first dose. In summary, the AE occurred mainly after the first dose, and were mild, like previous data from others immunizing agents in patients with rheumatoid arthritis. Vaccination did not worsen the degree of disease activity. immunemediated immune mediated (IMRDs COVID19 COVID 19 COVID-1 risks (RA outcomes comorbidities However SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- Safety Diseases, Diseases Brazil (AEs ChAdOx Oxford/AstraZeneca OxfordAstraZeneca Oxford AstraZeneca (Oxford/AstraZeneca Sinovac/Butantan. SinovacButantan Sinovac/Butantan . Sinovac Butantan (Sinovac/Butantan) diary 18 include 90 female 10 79 46,7%, 467 46,7% , 46 7 (46,7%) 39,4%, 394 39,4% 39 4 (39,4%) 30,5% 305 30 5 (30,5% 26,6%, 266 26,6% 26 6 (26,6%) 66% 66 (66 3 % 0.001 0001 0 001 62% 62 (62 22 22% 45% 45 (45 20 20% 37%, 37 37% (37%) 31%, 31 31% (31%) 23%, 23 23% (23%) 21% 21 (21% 18%. 18% (18%) 41,4% 414 41 (41,4 25 25% 0.02 002 02 51,4% 514 51 (51,4 27 27% related level summary COVID1 1 COVID- SARS-CoV (Sinovac/Butantan 9 46,7 (46,7% 39,4 (39,4% 30,5 (30,5 26,6 (26,6% (6 0.00 000 00 (4 (37% (31% (23% (21 (18% 41,4 (41, 0.0 51,4 (51, 46, (46,7 39, (39,4 30, (30, 26, (26,6 ( (37 (31 (23 (2 (18 41, (41 0. 51, (51 (46, (39, (30 (26, (3 (1 (5 (46 (39 (26

https://doi.org/10.1186/s42358-024-00397-5

Selection of superior cowpea lines derived from local cultivars for the Brazilian semiarid region
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Lopes, Anna Flávia de Sousa

; Aragão, Walter Frazão Lelis de

; Damasceno-Silva, Kaesel Jackson

; Rocha, Maurisrael de Moura

Pesquisa Agropecuária Brasileira

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2023, Volume 58 elocation e03391

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste trabalho foi selecionar linhagens superiores de feijão-caupi derivadas de cultivares locais para a região semiárida do sudeste do Piauí, Brasil. Foram avaliados 38 genótipos (36 linhagens e duas cultivares comercias) em um ensaio conduzido em delineamento de blocos ao acaso, com duas repetições, no município de Ipiranga do Piauí, no estado do Piauí. Foram avaliados os seguintes caracteres: número de dias para o início do florescimento, comprimento de vagem, número de grãos por vagem, peso de 100 grãos, qualidade comercial do grão e produtividade de grãos. Análises de deviance foram realizadas pela abordagem da máxima verossimilhança restrita e do melhor preditor não viesado, os parâmetros e os valores genéticos foram estimados, e a seleção simultânea foi realizada via índice de soma de postos. O teste da razão de verossimilhança mostrou diferença significativa entre os genótipos avaliados. As linhagens 36, 5, 24, 8, 2, 23, 29, 28, 34, 6, 19, 11, 7 e 20 são superiores para o conjunto de caracteres avaliados e, portanto, são as mais promissoras para compor o ensaio avançado do programa de melhoramento genético de feijão-caupi e gerar cultivares para os agricultores familiares da região semiárida do sudeste piauiense. feijãocaupi feijão caupi Piauí Brasil 3 36 (3 comercias acaso repetições florescimento vagem 10 viesado estimados postos 5 24 8 2 23 29 28 34 6 19 11 portanto piauiense ( 1

Abstract The objective of this work was to select superior cowpea lines derived from local cultivars for the semiarid region of southeastern Piauí, Brazil. A total of 38 genotypes (36 lines and two commercial cultivars) were evaluated in a randomized complete block design, with two replicates, in the municipality of Ipiranga do Piauí, in the state of Piauí. The following traits were evaluated: number of days to the onset of flowering, pod length, number of grains per pod, weight of 100 grains, commercial grain quality, and grain yield. Deviance analyzes were performed using the restricted maximum likelihood and best unbiased predictor approach, the parameters and genetic values were estimated, and simultaneous selection was carried out via the sum of ranks index. The likelihood ratio test showed a significant difference between the evaluated genotypes. Lines 36, 5, 24, 8, 2, 23, 29, 28, 34, 6, 19, 11, 7, and 20 are superior for the set of evaluated traits and, therefore, are the most promising to compose the advanced trial of the cowpea breeding program and to generate cultivars for family farmers in the semiarid region of southeastern Piauí. Piauí Brazil 3 36 (3 design replicates flowering length 10 quality yield approach estimated index 5 24 8 2 23 29 28 34 6 19 11 7 therefore ( 1

https://doi.org/10.1590/s1678-3921.pab2023.v58.03391

Association between sitagliptin plus vitamin D3 (VIDPP-4i) use and clinical remission in patients with new-onset type 1 diabetes: a retrospective case-control study D VIDPP4i VIDPPi VIDPP 4i i (VIDPP-4i newonset new onset diabetes casecontrol case control
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Pinheiro, Marcelo Maia

; Pinheiro, Felipe Moura Maia

; Arruda, Marcelo Müller de

; Beato, Geane Moron

; Verde, Graciele Alves Corrêa Lima

; Bianchini, Georgiana

; Casalenuovo, Pedro Rosário Moraes

; Argolo, Aline Aparecida Agostini

; Souza, Lucilene Telles de

; Pessoa, Flávia Gomes

; Hirose, Thiago Santos

; Senra, Eduardo Filgueiras

; Ricordi, Camillo

; Fabbri, Andrea

; Infante, Marco

; Diniz, Susana Nogueira

Archives of Endocrinology and Metabolism

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2023, Volume 67 N. 5 elocation e000652

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: The occurrence of partial remission (honeymoon phase) in type 1 diabetes (T1D) has been associated with a reduced risk of chronic microvascular complications of diabetes. We have published case reports showing that a combination therapy with the DPP-4 inhibitor sitagliptin plus vitamin D3 (VIDPP-4i) can prolong the honeymoon phase in patients with new-onset T1D. In the present case-control study, we investigated the frequency of occurrence of clinical remission (CR) in patients with new-onset T1D after VIDPP-4i treatment. Subjects and methods: In this case-control study, we collected data spanning 10 years from medical records of 46 patients (23 females) recently diagnosed with T1D. Overall, 27 participants with CR (insulin dose-adjusted glycated hemoglobin [IDAA1c] ≤ 9) at 12 or 24 months composed the case group, and 19 participants without CR served as the control group. Chi-square with Yates correction was used to analyze the association between VIDPP-4i use and CR, and odds ratio (OR) was used to determine the chance of CR due to VIDPP-4i treatment exposure. Results: In all, 37 patients (80.4%) experienced CR at some time over 24 months. The mean CR duration was 13.15 ± 9.91 months. Treatment with VIDPP-4i was significantly associated with CR. At 24 months, the OR of CR after VIDPP-4i exposure was 9.0 (95% confidence interval [CI] 2.21-30.18, p = 0.0036). Additionally, 9 (33.6%) and 4 (14.8%) patients in the VIDPP-4i group experienced insulin-free CR at 12 and 24 months, respectively. Conclusion: Therapy with VIDPP-4i was associated with a higher frequency and duration of the honeymoon phase. Randomized controlled trials are needed to confirm these findings. Objective TD T D (T1D DPP4 DPP DPP- VIDPP4i VIDPPi VIDPP 4i i (VIDPP-4i newonset new onset casecontrol study (CR methods 23 (2 females Overall 2 insulin doseadjusted dose adjusted IDAA1c IDAAc IDAA c [IDAA1c Chisquare Chi square (OR Results all 3 80.4% 804 80 (80.4% 1315 13 15 13.1 991 91 9.9 90 0 9. 95% 95 (95 CI [CI 2.2130.18, 2213018 2.21 30.18, 21 30 18 2.21-30.18 0.0036. 00036 0.0036 . 0036 0.0036) Additionally 33.6% 336 33 6 (33.6% 14.8% 148 14 8 (14.8% insulinfree free respectively Conclusion findings ( 80.4 (80.4 131 13. 99 (9 2130 2.2130.18 221301 221 2.2 3018 30.18 2.21-30.1 0003 0.003 003 33.6 (33.6 14.8 (14.8 80. (80. 213 2.2130.1 22130 22 2. 301 30.1 2.21-30. 000 0.00 00 33. (33. 14. (14. (80 2.2130. 2213 30. 2.21-30 0.0 (33 (14 (8 2.2130 2.21-3 0. (3 (1 2.213 2.21-

https://doi.org/10.20945/2359-3997000000652

Sintomas auditivos e vocais: uma análise da autopercepção de jogadores de jogos digitais vocais
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Reis, Ana Flávia Oliveira

; Hillesheim, Danúbia

; Ghirardi, Ana Carolina de Assis Moura

; Zucki, Fernanda

Audiology - Communication Research

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2023, Volume 28 elocation e2766

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo identificar os fatores associados a zumbido, percepção auditiva e risco de distúrbio vocal entre jogadores de jogos digitais. Métodos estudo transversal realizado com jogadores de jogos digitais por meio de questionários eletrônicos para coletar dados relacionados à saúde auditiva e vocal. Foram analisados três desfechos principais: zumbido, percepção auditiva (sensação da diminuição da audição) e risco de distúrbio de voz, mensurado pela Escala de Sintomas Vocais. As variáveis independentes referiram-se às características sociodemográficas, perfil dos jogadores e sinais e sintomas. Aplicaram-se os testes Qui-quadrado de Pearson e Exato de Fisher. Resultados a amostra foi composta por 59 jogadores, sendo a maioria do gênero masculino (79,7%), com idade entre 18 e 24 anos (69,5%). Com relação aos desfechos, 27,6% dos participantes apresentaram zumbido, 57,6%, risco de distúrbio vocal e 13,6% referiram sensação de diminuição da audição. Observou-se associação entre zumbido e cefaleia (p=0,024), zumbido e uso de smartphone (0,012), sensação de diminuição da audição e presença de ansiedade (p=0,049). O risco de distúrbio de voz associou-se ao maior tempo de horas jogadas por semana (p=0,020). Conclusão a autopercepção de zumbido esteve associada à cefaleia e ao uso de smartphone. Houve, ainda, associação entre ansiedade e sensação de diminuição da audição, além de risco de distúrbio de voz e maior tempo de horas jogadas por semana. principais Vocais referiramse se sociodemográficas sintomas Aplicaramse Aplicaram Quiquadrado Qui quadrado Fisher 5 79,7%, 797 79,7% , 79 7 (79,7%) 1 2 69,5%. 695 69,5% . 69 (69,5%) 276 27 6 27,6 576 57 57,6% 136 13 13,6 Observouse Observou p=0,024, p0024 p p=0,024 0 024 (p=0,024) 0,012, 0012 0,012 012 (0,012) p=0,049. p0049 p=0,049 049 (p=0,049) associouse associou p=0,020. p0020 p=0,020 020 (p=0,020) Houve ainda 79,7 (79,7% 69,5 (69,5% 27, 57,6 13, p002 p=0,02 02 (p=0,024 001 0,01 01 (0,012 p004 p=0,04 04 (p=0,049 (p=0,020 79, (79,7 69, (69,5 57, p00 p=0,0 (p=0,02 00 0,0 (0,01 (p=0,04 (79, (69, p0 p=0, (p=0,0 0, (0,0 (79 (69 p=0 (p=0, (0, (7 (6 p= (p=0 (0 ( (p= (p

ABSTRACT Purpose to identify factors associated with tinnitus, auditory perception and risk of voice disorders among digital game players. Methods cross-sectional study carried out with digital game players through electronic procedures to collect data related to hearing and vocal health. Three main outcomes were analyzed: tinnitus; auditory perception (sensation of diminished hearing) and risk of voice disorders, measured by the Vocal Symptoms Scale (VSS). The independent variables were related to sociodemographic characteristics, player profile and signs and symptoms. Pearson’s chi-square test and Fisher’s exact test were applied. Results the sample consisted of 59 players. Most were male (79.7%) and ages between 18 and 24 years (69.5%). Regarding the terms, 27.6% had tinnitus, 57.6% were at risk of vocal disorder and 13.6% reported hearing loss. There was an association between tinnitus and headache (p=0.024), tinnitus and smartphone use (0.012), hearing loss and anxiety (p= 0.049). A risk of voice disorder(s ) was associated with more hours played per week (p=0.020). Conclusion self-perceived tinnitus was associated with headache and smartphone use; there was also an association between anxiety and the feeling of hearing impairment, in addition to the risk of voice disorders and more hours played per week. crosssectional cross sectional health analyzed sensation VSS. VSS . (VSS) characteristics symptoms Pearsons Pearson s chisquare chi square Fishers Fisher applied 5 79.7% 797 79 7 (79.7% 1 2 69.5%. 695 69.5% 69 (69.5%) terms 276 27 6 27.6 576 57 57.6 136 13 13.6 p=0.024, p0024 p p=0.024 , 0 024 (p=0.024) 0.012, 0012 0.012 012 (0.012) p= (p 0.049. 0049 0.049 049 0.049) p=0.020. p0020 p=0.020 020 (p=0.020) selfperceived self perceived impairment (VSS 79.7 (79.7 69.5 (69.5% 27. 57. 13. p002 p=0.02 02 (p=0.024 001 0.01 01 (0.012 004 0.04 04 (p=0.020 79. (79. 69. (69.5 p00 p=0.0 (p=0.02 00 0.0 (0.01 (79 (69. p0 p=0. (p=0.0 0. (0.0 (7 (69 p=0 (p=0. (0. ( (6 (p=0 (0

https://doi.org/10.1590/2317-6431-2022-2766pt

10.

Bullous lesions following phototherapy in a newborn
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Toscano, Marina Moura

; Cintra, Flavia Fernandes

; Resende, Ludmila Oliveira

; Casteleti, Paula

; Moraes, Lucas Hirano Arruda

; Rivitti-Machado, Maria Cecilia da Matta

; Nico, Marcello Menta Simonsen

; Del Bigio, Juliana Zoboli

; Carvalho, Werther Brunow de

einstein (São Paulo)

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2023, Volume 21 elocation eRC0256

Abstract: En | Text: En | PDF: En

ABSTRACT A male infant presented with progressive jaundice immediately after birth. Fecal acholia and choluria associated with extensive bullous skin lesions in his trunk, abdomen, and upper and lower limbs developed during phototherapy. Several diagnostic hypotheses were presented, including neonatal porphyria, hemochromatosis, Alagille syndrome, and neonatal lupus. A 24-hour urine sample for the dosage of urinary porphyrins was collected, showing high results (1823.6µg in 100mL). At 50 days of life, fluorescence spectroscopy using a Wood’s lamp revealed simultaneous bright red fluorescence of urine-stained diapers and sample blood. A definitive diagnosis of congenital erythropoietic porphyria was made following identification of a mutation of the uroporphyrinogen synthetases III gene on genetic testing. The patient was subsequently maintained in a low light environment since then, resulting in improvement of the lesions. Congenital erythropoietic porphyria is a disease of the group of porphyrias that presents shortly after birth with blistering occurring in regions exposed to the sun or other ultraviolet light. Atrophic scars, mutilated fingers, and bright red fluorescence of the urine and teeth may also be observed. There is no specific treatment, and prophylaxis comprising a total avoidance of sunlight is generally recommended. A high degree of suspicion is required for diagnosis. An early diagnosis can lead to less damage. Here, we present the case of a newborn with congenital erythropoietic porphyria diagnosed after presenting with bullous lesions secondary to phototherapy. trunk abdomen phototherapy hemochromatosis syndrome lupus 24hour hour 24 collected 1823.6µg 18236µg µg 1823 6µg 100mL. 100mL mL . 100mL) 5 life Woods Wood s urinestained stained blood testing then scars fingers observed treatment recommended damage Here 2 182 18 1

https://doi.org/10.31744/einstein_journal/2023rc0256

11.

COVID-19-related multisystem inflammatory syndrome in adult: the first death in Brazil COVID19related COVIDrelated COVID 19 related adult 1
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Salomão, Maria Lúcia Machado

; Queiroz, Flávia

; Mendes, Lina de Moura

; Lima, Taiza Maschio de

; Tuckumantel, Murillo de Souza

; Catelan, Marcia Wakai

; Oliveira, Neymar Elias de

; Nogueira, Maurício Lacerda

; Estofolete, Cassia Fernanda

Revista do Instituto de Medicina Tropical de São Paulo

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2023, Volume 65 elocation e50

Abstract: En | Text: En | PDF: En

ABSTRACT The precise pathogenesis of COVID-19-related multisystem inflammatory syndrome remains largely elusive, despite its rarity. The syndrome symptoms often overlap with those of other infections, posing challenges for prompt diagnosis. A male patient, 34 years old, was admitted with suspicion of severe dengue, rapidly progressing to multiple organ dysfunction. Dengue tests resulted negative, and he passed away after four days. This case occurred approximately four weeks after the initial onset of COVID-19 and met all diagnostic criteria as defined by the Centers for Disease Control and Prevention. This report presents the first documented case of fatal multisystem inflammatory syndrome in adult (MIS-A) in Brazil. Recognizing the significance of suspecting this syndrome and promptly initiating treatment at an early stage are essential for minimizing damage and mortality. COVID19related COVIDrelated COVID 19 related elusive rarity infections diagnosis patient 3 old dengue dysfunction negative days COVID19 COVID-1 Prevention MISA MIS (MIS-A Brazil mortality 1 COVID1 COVID-

https://doi.org/10.1590/s1678-9946202365050

12.

Types of analysis of validation studies in nursing: scoping review
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Barreto Tavares Chiavone, Flávia

; Belmiro de Andrade, Fernanda

; Moura da Silva, Anderson Felipe

; Campos de Azevedo, Isabelle

; Soares Martins, Quenia Camille

; Pereira Santos, Viviane Euzebia

Investigación y Educación en Enfermería

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dec 2022, Volume 40 N. 3 elocation e09

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen Objetivo. Identificar y mapear los tipos de análisis de los estudios de validación de enfermería. Métodos. Esta es una revisión de alcance, con recolección realizada en julio de 2020. Se consideraron los siguientes indicadores para la extracción de datos: año de publicación, país de origen, tipo de estudio, nivel de evidencia, referencias científicas para la validación y tipos de análisis. Los datos se recolectaron en las siguientes bases: U.S. National Library of Medicine, Cumulative Index to Nursing and Allied Health Literature, SCOPUS, COCHRANE, Web of Science, PSYCHINFO, Latin American and Caribbean Literature in Health Sciences, CAPES Theses and Dissertation Portal, Education Resources Information Center, The National Library of Australia's Trobe, Academic Archive Online, DART-Europe E-Theses Portal, Electronic Theses Online Service, Open Access Scientific Repository of Portugal, National ETD Portal, Theses Canada y Tesis y disertaciones de América Latina. Resultados. la muestra la constituyeron 881 estudios, con predominio de artículos (841; 95.5%), con una frecuencia mayor de publicaciones en 2019 (152; 17.2%), de origen brasileño (377; 42.8%), del tipo de estudio metodológico. (352; 39.9%). Polit y Beck se destacaron como referencia metodológica (207; 23.5%) y el Alpha de Cronbach (421; 47.8%) como prueba estadística. En cuanto al tipo de análisis, se destacó el análisis factorial exploratorio y el índice de validación de contenido. Conclusión. En más de la mitad de los estudios fue evidente la utilización de, al menos, un método de análisis, lo que implicó la necesidad de realizar varias pruebas estadísticas con el fin de evaluar la validación del instrumento empleado y mostrar su fiabilidad.

Abstract Objective. To identify and map the types of analysis in nursing validation studies. Methods. This is a scoping review with collection carried out in July 2020. The following data extraction indicators were considered: year of publication, country of origin, type of study, level of evidence, scientific references for validation and types of analyses. Data were collected in the following bases: U.S. National Library of Medicine, Cumulative Index to Nursing and Allied Health Literature, SCOPUS, COCHRANE, Web of Science, PSYCHINFO, Latin American and Caribbean Literature in Health Sciences, CAPES Theses and Dissertation Portal, Education Resources Information Center, The National Library of Australia's Trobe, Academic Archive Online, DART-Europe E-Theses Portal, Electronic Theses Online Service, Open Access Scientific Repository of Portugal, National ETD Portal, Theses Canada, Theses and dissertations from Latin America. Results. The sample consisted of 881 studies, with a predominance of articles (841; 95.5%), with a prevalence of publications in 2019 (152; 17.2%), of Brazilian origin (377; 42.8%), of the methodological study type (352; 39.9%). Polit and Beck stood out as the methodological reference (207; 23.5%) and Cronbach's Alpha (421; 47.8%) as the statistical test. Regarding the type of analysis, the exploratory factor analysis and the content validation index stood out. Conclusion. The use of at least one method of analysis was evident in more than half of the studies, which implied the need to carry out several statistical tests in order to evaluate the validation of the instrument used and show its reliability.

Resumo Objetivo. Identificar e mapear os tipos de análises dos estudos de validação em enfermagem. Métodos. Trata-se de uma scoping review, com coleta realizada em julho de 2020. Considerou-se como indicadores de extração de dados: ano de publicação, país de origem, tipo de estudo, nível de evidência, os referenciais científicos para validação e os tipos de análises. Os dados foram coletados nas bases: U.S. National Library of Medicine, Cumulative Index to Nursing and Allied Health Literature, SCOPUS, COCHRANE, Web of Science, PSYCHINFO, Literatura Latino-Americana e do Caribe em Ciências da Saúde, Portal de Teses e Dissertações da CAPES, Education Resources Information Center, The National Library of Australia’s Trobe, Academic Archive Online, DART-Europe E-Theses Portal, Electronic Theses Online Service, Repositório Científico de Acesso Aberto de Portugal, National ETD Portal, Theses Canada, Teses e dissertações da América latina. Resultados. A amostra foi de 881 estudos, com predomínio de artigos (841; 95.5%), com prevalência de publicações em 2019 (152; 17.2%), de origem brasileira (377; 42.8%), do tipo estudo metodológico (352; 39.9%). Sobressaiu-se Polit e Beck como referencial metodológico (207; 23.5%) e Alfa de Cronbach (421; 47.8%) como teste estatístico. Em relação ao tipo de análise destacou-se a análise fatorial exploratória e o índice de validação de conteúdo. Conclusão. Em mais da metade dos estudos ficou evidente a utilização de pelo menos um método de análise, o que implicou a necessidade de realização de diversos testes estatísticos para avaliar a validade do instrumento utilizado e mostrar sua confiabilidade.

https://doi.org/10.17533/udea.iee.v40n3e09

13.

Dietas artificiais para criação de Condylorrhiza vestigialis (Guenée, 1854) (Lepidoptera: Crambidae), principal praga do gênero Populus
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Corrêa, Flávia de Albuquerque Seródio

; Sousa, Nilton José

; Rezende, Eduardo Henrique

; Corrêa, Renato de Moura

; Giongo, Marcos

; Batista, Antonio Carlos

Ciência Florestal

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mar 2022, Volume 32 N. 1 Pages 351 - 370

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O objetivo do trabalho foi testar dietas artificiais para a criação em laboratório de Condylorrhiza vestigialis (Guenée, 1854) (Lepidoptera: Crambidae), que é considerada a principal praga de árvores do gênero Populus, no Brasil. Foram testadas três formulações de dietas artificiais com base na dieta desenvolvida por Greene, e duas alterações na dieta proposta por Hoffmann-Campo. Foram avaliados o número de larvas mortas; o número de larvas canibalizadas; a quantidade de pupas mal-formadas; o número de ínstares larvais; a quantidade de pupas inviáveis; o número de adultos mal-formados; e o número de adultos normais. Os dados obtidos foram submetidos à análise estatística ANOVA e ao teste de comparação de médias, Student-Newman-Keuls (SNK), ao nível de 5% de probabilidade de erro, sendo utilizado como delineamento estatístico, o inteiramente casualizado. Também foram avaliados parâmetros biológicos das mariposas alimentadas com cada dieta testada: período de incubação dos ovos (em dias); duração da fase larval, pré-pupa e pupa (em dias); peso das pupas fêmeas e machos com 5 dias de idade (em gramas); razão sexual. A Dieta Base 2 é a mais eficiente e viável dentre as dietas testadas para a criação de Condylorrhiza vestigialis em laboratório, pois é a que proporciona o desenvolvimento mais eficiente durante as etapas do seu ciclo de vida e a que gera maiores quantidades de adultos saudáveis e férteis, possibilitando assim o aumento do número de indivíduos e a manutenção da população.

ABSCTRACT The objective of the work was to test artificial diets for the rearing in the laboratory of Condylorrhiza vestigialis (Guenée, 1854) (Lepidoptera: Crambidae), which is considered the main pest of trees of the genus Populus in Brazil. Three formulations of artificial diets were tested based on the diet developed by Greene, and two changes in the diet proposed by Hoffmann-Campo. The number of dead larvae was evaluated; number of cannibalized larvae; amount of malformed pupae; number of larval instars; number of unviable pupae; number of malformed adults; and number of normal adults. The data obtained were submitted to ANOVA statistical analysis and to the means comparison test, Student-Newman-Keuls (SNK), at the level of 5% probability of error, with the statistical design used being completely randomized. The biological parameters of the moths fed with each tested diet were also evaluated: incubation period of the eggs (in days); duration of the larval phase, pre-pupa and pupa (in days); weight of female and male pupae at 5 days of age (in grams); sexual reason. The Base 2 Diet is the most efficient and feasible among the diets tested for the rearing of Condylorrhiza vestigialis in the laboratory, providing the most efficient development during the stages of its life cycle, generating greater quantities of healthy and fertile adults, enabling the increase of the number of individuals and the maintenance of the population.

https://doi.org/10.5902/1980509855335

14.

Estratégias para promoção da saúde e seus impactos na qualidade de vida de adultos hipertensos: revisão integrativa
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Borges, Fernanda Moura

; Silva, Flávia Raymme Soares e

; Rodrigues, Malvina Thaís Pacheco

; Mascarenhas, Márcio Dênis Medeiros

; Silva, Ana Roberta Vilarouca da

; Machado, Ana Larissa Gomes

Cadernos Saúde Coletiva

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mar 2022, Volume 30 N. 1 Pages 146 - 157

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução A promoção da saúde é uma prática que qualifica o cuidado e impacta positivamente a qualidade de vida, especialmente em indivíduos com hipertensão que requerem acompanhamento por toda a vida. Objetivo O presente estudo objetivou investigar as estratégias desenvolvidas para a promoção da saúde e seus impactos na qualidade de vida de adultos hipertensos. Método Foi realizada uma revisão integrativa por meio de consulta às bases de dados Lilacs, Medline, SciELO, Scopus e Web of Science. Foram incluídos artigos originais sobre práticas de promoção da saúde realizadas com adultos hipertensos, publicados nos últimos cinco anos, nos idiomas português, inglês ou espanhol e disponíveis na íntegra. Foram excluídas as pesquisas realizadas com grávidas, adolescentes e crianças hipertensas. Resultados Foram incluídos 12 artigos na revisão. As principais estratégias consistiram em práticas grupais, que consideraram o usuário como protagonista do cuidado. As atividades desenvolvidas se mostraram eficazes, pois promoveram a redução de níveis pressóricos, a adesão ao tratamento, a mudança no estilo de vida, a melhor percepção da qualidade de vida e o empoderamento dos adultos hipertensos. Conclusão As estratégias para a promoção da saúde são fundamentais para possibilitar aos adultos hipertensos a capacidade de analisar seu estado de saúde e tomar decisões para o planejamento e a manutenção do autocuidado.

Abstract Background Health promotion is a practice that qualifies care and positively impacts the quality of life, especially in individuals with hypertension who need lifelong monitoring. Objective This study aimed to investigate the strategies developed for health promotion and their impacts on the quality of life of hypertensive adults. Method An integrative review was carried out by consulting Lilacs, Medline, SciELO, Scopus and Web of Science databases. Original articles on health promotion practices conducted with hypertensive adults, published in the last five years, in Portuguese, English or Spanish, and available in full, were included. Researches with hypertensive pregnant women, adolescents and children were excluded. Results Twelve articles were included in the review. The main strategies consisted of group community interventions, which considered the user as protagonist of care. Activities developed proved to be effective, as they promoted the reduction of blood pressure levels, as well as adherence to treatment, change in lifestyle, better perception of quality of life and empowerment of hypertensive adults. Conclusion Strategies for health promotion are essential to enable hypertensive adults to analyze their health status and make decisions for planning and maintaining self-care.

https://doi.org/10.1590/1414-462x202230010110

15.

Validation of the brazilian version of the oral health impact profile - Aesthetic questionnaire
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Hanan, Simone Assayag

; Cohen-Carneiro, Flávia

; Herkrath, Fernando José

; Oliveira, Branca Heloisa de

; Loguércio, Alessandro Dourado

; Martins, Leandro de Moura

; Herkrath, Ana Paula Corrêa de Queiroz

Brazilian Dental Journal

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feb 2022, Volume 33 N. 1 Pages 77 - 86

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo do estudo foi desenvolver a versão brasileira do Oral Health Impact Profile - Aesthetic Questionnaire (OHIP-Aes-Braz) e testar suas propriedades psicométricas. As versões de teste do questionário foram desenvolvidas por um painel de especialistas e um pré-teste foi realizado em um grupo focal. Os dados usados para testar suas propriedades psicométricas foram obtidos a partir de um ensaio clínico randomizado controlado de clareamento dental. Setenta e nove brasileiros adultos foram incluídos. Os questionários foram aplicados antes do tratamento clareador (baseline), uma semana (T1) e um mês após a intervenção (T2). A confiabilidade foi avaliada em termos de consistência interna e estabilidade, enquanto a validade foi avaliada pela validade de critério e de construto. A sensibilidade à mudança foi avaliada pela comparação entre os escores totais no baseline e T2, usando o teste de Wilcoxon ((=0,05). Tanto a estabilidade quanto a consistência interna (coeficiente de correlação intraclasse=0,95, alfa de Cronbach=0,92) mostraram-se adequadas. A validade de construto foi confirmada uma vez que a correlação dos escores do OHIP-Aes-Braz com a satisfação com a cor dos dentes e a autopercepção da saúde bucal foram na direção esperada. Uma correlação positiva entre OHIP-Aes-Braz e OHIP-14 (r s =0,63) e OIDP (r s =0,77) foi observada. O instrumento foi responsivo uma vez que as diferenças nos escores totais antes e depois do tratamento foram estatisticamente significantes (p<0,001). O OHIP-Aes-Braz apresentou boas propriedades psicométricas e mostrou sensibilidade a mudanças na avaliação estética em adultos brasileiros submetidos ao clareamento dental. Um instrumento válido e confiável permite uma avaliação adequada da qualidade de vida relacionada à saúde bucal em pacientes brasileiros submetidos a intervenções odontológicas estéticas.

Abstract The aim of the study was to develop the Brazilian version of the Oral Health Impact Profile - Aesthetic Questionnaire (OHIP-Aes-Braz) and test its psychometric properties. The questionnaire test versions were developed by a panel of experts and a pre-test was conducted in a focus group. Data used for testing its psychometric properties were obtained from a randomized controlled clinical trial on tooth bleaching. Seventy-nine Brazilian adults were included. The questionnaires were applied before tooth bleaching treatment (baseline), one week (T1), and one month after the intervention (T2). Reliability was assessed in terms of internal consistency and stability, while validity was ascertained by criterion and construct validity. The sensitivity to change was assessed comparing the total scores at baseline and T2, using the Wilcoxon test (α = 0.05). Both stability and internal consistency (intra-class correlation coefficient=0.95, Cronbach’s α = 0.92) proved to be adequate. Construct validity was confirmed as the correlation between OHIP-Aes-Braz scores with tooth color satisfaction and self-perceived oral health were in the expected direction. A positive correlation between OHIP-Aes-Braz and OHIP-14 (rs=0.63) and OIDP (rs=0.77) was observed. The instrument was responsive once differences in total scores before and after treatment were statistically significant (p<0.001). The OHIP-Aes-Braz presented good psychometric properties and showed sensitivity to change regarding aesthetics evaluation in Brazilian adults treated with tooth bleaching. A valid and reliable instrument allows a suitable assessment of oral health-related quality of life in Brazilian patients submitted to aesthetics dental interventions.

https://doi.org/10.1590/0103-6440202204237

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