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ABSTRACT Respiratory syncytial virus (RSV) infections constitute a significant cause of morbidity, hospitalization, school and work absenteeism, as well as mortality worldwide, including in Paraguay. Currently, tools for RSV prevention are available. In 2012, Paraguay approved the use of palivizumab (MedImmune, USA), a monoclonal antibody produced through recombinant DNA technology. This antibody is administered in 5 doses, every 30 days and is indicated in infants born prematurely and those with cardiopulmonary disorders. Furthermore, a novel tool for RSV prevention has recently become available. Nirsevimab, a long-acting monoclonal antibody specific to the prefusion conformation of the F protein, has been approved by both the European Medicines Agency (EMA) and the Food and Drug Administration (FDA). This monoclonal antibody is indicated for the prevention of acute lower respiratory tract infections caused by RSV in newborns and infants born during or entering their first RSV season, as well as in premature infants and infants up to 24 months of age who remain vulnerable to severe RSV disease during their second RSV season. After analyzing the epidemiological situation of RSV in our country and evaluating the evidence of efficacy, efficiency, and effectiveness of this monoclonal antibody, academic institutions, scientific societies, and non-governmental and governmental organizations developed consensus guidelines on a new prevention alternative for the prevention of RSV infections, suggesting the incorporation of Nirsevimab in children under 12 months of age before their first RSV season and replacing Palivizumab. The new monoclonal has the potential to change the panorama of RSV infections in infants and produce an impact on the reduction of infant mortality and morbidity reducing the burden on the health system by decreasing hospital bed occupancy both in wards and in intensive care units, as well as the decrease in the burden on caregivers, physicians and health care providers.

RESUMEN Las infecciones por el VSR en constituyen una causa importante de morbilidad, hospitalización, ausentismo escolar y laboral, así como de mortalidad, en el mundo, así como en el Paraguay.En la actualidad, existen herramientas para la prevención del VSR. En el año 2012, el Paraguay, ha incorporado el palivizumab (MedImmune, EE. UU.), anticuerpo monoclonal, producido por tecnología de DNA recombinante. Este anticuerpo se administra en 5 dosis, cada 30 días y está indicado en lactantes nacidos prematuros y aquellos con trastornos cardiopulmonares. Por otro lado, actualmente se cuenta con una nueva herramienta para la prevención del VSR. El anticuerpo monoclonal de vida media prolongada Nirsevimab, específico para la conformación de prefusión de la proteína F, aprobado por EMA y FDA. Este monoclonal, está indicado para la prevención de las Infecciones respiratorias agudas bajas, causada por VSR en recién nacidos y lactantes nacidos durante o al ingresar a su primera temporada de VSR, en prematuros y lactantes hasta los 24 meses de edad que siguen siendo vulnerables a la enfermedad grave por VSR durante su segunda temporada de VSR. Luego de analizar la situación epidemiológica del VSR en el país así como la evidencia de eficacia, eficiencia y efectividad de este monoclonal; instituciones académicas, sociedades científicas, organizaciones no gubernamentales y gubernamentales se reunieron y elaboraron un consenso interinstitucional para la prevención de las infecciones por VSR, sugiriendo la incorporación del Nirsevimab, en menores de 12 meses de edad antes de su primera temporada de VSR y en reemplazo del Palivizumab, debido a que el nuevo monoclonal tiene el potencial de cambiar el panorama de las infecciones por VSR en el lactante y producir un impacto en la reducción la mortalidad y morbilidad infantil; reduciendo la carga al sistema de salud, en lo que se refiere a la disminución de la ocupación de camas hospitalarias tanto en sala como en unidades de cuidados intensivos, así como la disminución de la carga para los cuidadores, médicos y proveedores de atención médica y la mortalidad infantil.

https://doi.org/10.31698/ped.51022024009

Potential use of methane gas from the Villavicencio sanitary landfill, Colombia
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Ramírez-Ríos, Luisa F

; Becerra-Moreno, Dorance

; Ortega-Contreras, Judith Yamile

Ingeniería y competitividad

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aug 2024, Volume 26 N. 2 elocation e-21314019

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract The study evaluates the generation and recovery capacity of methane at the Villavicencio Landfill in Colombia, using the LandGEM model. It shows a significant increase in methane generation, rising from about 1.5 million cubic meters in 2010 to over 8.5 million in 2020, indicating a growing urgency to implement effective mitigation measures. It was estimated that by the year 2042, the electrical energy production from methane could be 248.067 kW/day, capable of supplying about 43.705 homes monthly. Additionally, thermal energy generation would be 468.572 kWh/day, useful for industrial processes. Management scenarios were proposed, where, for example, operational optimization could increase electric production to 342.333 kW/day, benefiting more than 60.000 homes monthly. The conclusions highlight the direct correlation between the amount of waste and methane generation, and the significant potential for converting these emissions into energy, pointing towards regional energy self-sufficiency and sustainability. Methane recovery represents a valuable alternative to the dependence on fossil fuels and for the development of a circular economy.

Resumen El estudio evalúa la generación y capacidad de recuperación de metano en el Relleno Sanitario de Villavicencio, Colombia, mediante el modelo LandGEM. En donde se observa un aumento significativo en la generación de metano, pasando de alrededor de 1,5 millones de metros cúbicos en 2010 a más de 8,5 millones en 2020, lo que indica una creciente urgencia por implementar medidas de mitigación efectivas. Se estimó que, para el año 2042, la producción de energía eléctrica del metano podría ser de 248.067 kW/día, capaz de abastecer a unos 43.705 hogares mensualmente. Asimismo, se generaría energía térmica de 468.572 kWh/día, útil para procesos industriales. Se plantearon escenarios de gestión, donde, por ejemplo, la optimización operacional podría aumentar la producción eléctrica a 342.333 kW/día, beneficiando a más de 60.000 hogares mensualmente. Las conclusiones resaltan la correlación directa entre la cantidad de residuos y la generación de metano, y el significativo potencial de convertir estas emisiones en energía, apuntando hacia la autosuficiencia y sostenibilidad energética regional. El aprovechamiento del metano representa una alternativa valiosa frente a la dependencia de combustibles fósiles y para el desarrollo de una economía circular.

https://doi.org/10.25100/iyc.v26i2.14019

Durabilidad natural de la madera de seis especies de importancia comercial en México
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Ontiveros-Moreno, Yolanda

; Colín-Urieta, Serafín

; Carrillo-Parra, Artemio

; López-Camacho, Edgar Benjamín

; Corral-Rivas, José Javier

; Hernández-Díaz, José Ciro

; Prieto-Ruíz, José Ángel

Revista mexicana de ciencias forestales

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aug 2024, Volume 15 N. 84 Pages 132 - 154

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract The natural durability of wood is defined as its intrinsic ability to resist degradation caused by biotic and abiotic factors. There are few records of natural wood durability in Mexico; in this study, it was determined based on the degradation of the wood of six commercial species: Pinus durangensis, P. strobiformis, P. cooperi, Juniperus deppeana, Quercus sideroxyla, and Alnus acuminata, in addition to Fagus sylvatica as the control. Test specimens were placed in contact with soil for 12 months at the Mineral de Nuestra Señora de la Candelaria Ecological Reserve of in Cósala, Sinaloa, and at the Las Bayas property in the state of Durango. Five specimens of each species were buried at 50 % of their length and analyzed following the UNE-EN 252:2015 European standard for determining degradation in wood, and UNE-EN 350:2016 for estimating durability. Due to the absence of normality (p<0.05) in the degradation data, the Kruskall-Wallis nonparametric test was used to determine statistical differences between species, locality, and puncture area. Statistical analysis was performed in the R-Studio program. According to UNE-EN 252:2015 and UNE-EN 350:2016, J. deppeana was the most durable wood classified as Class 1; Q. sideroxyla, P. strobiformis, P. durangensis and F. sylvatica (control) were Class 2 timbers, with slight damage; and A. acuminata and P. cooperi were classified as Class 3, with evident degradation. It is concluded that J. deppeana has the most durable wood.

Resumen La durabilidad natural de la madera se define como la capacidad intrínseca que tiene para resistir la degradación ocasionada por factores bióticos y abióticos. Existen pocos registros de la durabilidad natural de la madera en México; en este estudio se determinó con base en la degradación de la madera de seis especies comerciales: Pinus durangensis, P. strobiformis, P. cooperi, Juniperus deppeana, Quercus sideroxyla y Alnus acuminata, además de Fagus sylvatica como testigo. Se usaron probetas colocadas en contacto con el suelo por 12 meses en dos localidades: la Reserva Ecológica del Mineral de Nuestra Señora de la Candelaria en Cósala, Sinaloa, y el predio Las Bayas, Durango. Cinco probetas de cada especie se enterraron a 50 % de su longitud y se analizaron siguiendo la norma europea UNE-EN 252:2015 que determina la degradación en la madera, y la UNE-EN 350:2016 para la durabilidad. Debido a la ausencia de normalidad (p<0.05) en los datos de degradación, se usó la prueba no paramétrica de Kruskall-Wallis para determinar diferencias estadísticas entre especies, localidad y área de punzado. El análisis estadístico se realizó en el programa R-Studio. De acuerdo con las normas UNE-EN 252:2015 y UNE-EN 350:2016, J. deppeana fue la madera más durable clasificada como Clase 1; Q. sideroxyla, P. strobiformis, P. durangensis y F. sylvatica (control), fueron maderas Clase 2, con ligero daño; A. acuminata y P. cooperi clasificaron como Clase 3, con evidente degradación. Se concluye que J. deppeana presenta la madera más durable.

https://doi.org/10.29298/rmcf.v15i84.1453

Métodos difusos de medición multidimensional de la pobreza: una revisión del estado del arte
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Asmat Uceda, Rafael Marcel

; Vergara Moreno, Edmundo Rubén

El trimestre económico

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jun 2024, Volume 91 N. 362 Pages 437 - 475

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract This paper reviews the different approaches and policies that are most used in the literature to measure the level of poverty with tools of fuzzy logic. These policies are based on the integrated measurement method (IM), which combines poverty line methods and unmet basic needs. Moreover, we present the most recent studies on the measurement of the level of poverty in different sectors and populations, as well as the more relevant conclusions of the work.

Resumen En este trabajo se revisan los diversos enfoques y políticas más utilizados en la literatura para medir el nivel de pobreza mediante las herramientas de la lógica difusa. Estas políticas se basan en el método de medición integrado (MI), el cual combina los métodos de la línea de pobreza y las necesidades básicas insatisfechas. También se presentan los estudios más recientes sobre la medición del nivel de pobreza en diferentes sectores y poblaciones. Finalmente, se plantean las conclusiones más relevantes del trabajo realizado.

https://doi.org/10.20430/ete.v91i362.2066

Incidence of childhood cancer in Latin America and the Caribbean: coverage, patterns, and time trends
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de Paula Silva, Neimar

; Colombet, Murielle

; Moreno, Florencia

; Erdmann, Friederike

; Dolya, Anastasia

; Piñeros, Marion

; Stiller, Charles A

; Steliarova-Foucher, Eva

; Steliarova-Foucher, E

; Colombet, M

; Gloeckler Ries, LA

; Moreno, F

; Dolya, A

; Shin, HY

; Hesseling, P

; Stiller, CA

; Moreno, F

; Laura, EA

; Duarte, MA

; Alonso, M

; Prince, MA

; Diumenjo, MC

; Arias Ondicol, N

; Lima, CA

; Mundim Pena, GP

; Asturian Laporte, C

; de Oliveira, JC

; Pontes de Aquino, JA

; Vallebuona, C

; Galaz, JC

; Umaña, ME

; Espinoza, C

; Vargas Gallagher, SM

; Uribe, CJ

; Bravo, LE

; Arias Ortiz, NE

; Yepez Chamorro, MC

; Torres Alvarado, G

; Galán Alvarez, YH

; Martinez Reyes, FC

; Tanca Campozano, J

; Castillo Calvas, JC

; Mendoza Alava, M

; Cueva Ayala, P

; Roué, T

; Deloumeaux, J

; Joachim, C

; Duarte Muñoz, F

; Hanchard, B

; Fajardo-Gutiérrez, A

; Payet, E

; Albújar, PF

; Zavala Zegarra, DE

; Barrios, E

Revista Panamericana de Salud Pública

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2024, Volume 48 elocation e11

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

resumen está disponible en el texto completo

ABSTRACT Objective. To provide a comprehensive overview of geographical patterns (2001–2010) and time trends (1993–2012) of cancer incidence in children aged 0–19 years in Latin America and the Caribbean (LAC) and interpret the findings in the context of global patterns. Methods. Geographical variations in 2001–2010 and incidence trends over 1993–2012 in the population of LAC younger than 20 years were described using the database of the third volume of the International Incidence of Childhood Cancer study containing comparable data. Age-specific incidence per million person-years (ASR) was calculated for population subgroups and age-standardized (WSR) using the world standard population. Results. Overall, 36 744 unique cases were included in this study. In 2001–2010 the overall WSR in age 0–14 years was 132.6. The most frequent were leukemia (WSR 48.7), central nervous system neoplasms (WSR 23.0), and lymphoma (WSR 16.6). The overall ASR in age group 15–19 years was 152.3 with lymphoma ranking first (ASR 30.2). Incidence was higher in males than in females, and higher in South America than in Central America and the Caribbean. Compared with global data LAC incidence was lower overall, except for leukemia and lymphoma at age 0–14 years and the other and unspecified tumors at any age. Overall incidence at age 0–19 years increased by 1.0% per year (95% CI [0.6, 1.3]) over 1993–2012. The included registries covered 16% of population aged 0–14 years and 10% of population aged 15–19 years. Conclusions. The observed patterns provide a baseline to assess the status and evolution of childhood cancer occurrence in the region. Extended and sustained support of cancer registration is required to improve representativeness and timeliness of data for childhood cancer control in LAC.

RESUMO Objetivo. Apresentar uma visão abrangente dos padrões geográficos (2001 a 2010) e das tendências temporais (1993 a 2012) da incidência de câncer em crianças e jovens de 0 a 19 anos na América Latina e no Caribe (ALC) e interpretar os resultados no contexto de padrões mundiais. Métodos. Foram descritas variações geográficas de 2001 a 2010 e tendências de incidência de 1993 a 2012 na população com menos de 20 anos da ALC usando informações comparáveis da base de dados do terceiro volume do estudo International Incidence of Childhood Cancer. Foram calculadas taxas de incidência específica por idade por milhão de pessoas-ano (ASR, na sigla em inglês) para subgrupos populacionais e taxas padronizadas por idade usando a população padrão mundial (WSR, na sigla em inglês). Resultados. No total, foram incluídos 36 744 casos únicos. No período de 2001 a 2010, a WSR para todos os tumores combinados na faixa etária de 0 a 14 anos foi de 132,6. Os diagnósticos mais frequentes foram leucemia (WSR de 48,7), neoplasias do sistema nervoso central (WSR de 23,0) e linfoma (WSR de 16,6). A ASR para todos os tumores combinados na faixa etária de 15 a 19 anos foi de 152,3, e a maior taxa foi a de linfoma (ASR de 30,2). A incidência foi maior no sexo masculino do que no sexo feminino e maior na América do Sul do que na América Central e no Caribe. De modo geral, em comparação com as estimativas mundiais, a incidência na ALC foi menor, exceto para leucemia e linfoma entre 0 e 14 anos e para outros tumores e tumores não especificados em qualquer idade. A taxa de incidência na faixa etária de 0 a 19 anos aumentou em 1,0% ao ano (IC de 95% [0,6, 1,3]) entre 1993 e 2012. Os registros incluídos cobriam 16% da população de 0 a 14 anos e 10% da população de 15 a 19 anos. Conclusões. Os padrões observados servem de referência para avaliar o status e a evolução da ocorrência de câncer infantil na região. É necessário garantir um apoio ampliado e consistente aos registros de câncer para aprimorar a representatividade e a disponibilidade das informações em tempo adequado para o controle do câncer infantil na ALC.

https://doi.org/10.26633/rpsp.2024.11

Comportamiento de tomates criollos (Solanum lycopersicum L.) del sureste de México al complejo Bemisia tabaci - Begomovirus
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Ruiz-Sánchez, Esaú

; Latournerie-Moreno, Luis

; Chan-Escalante, Zaci F

; Lara-Martín, Alicia R.

; Ruiz Jiménez, Ana L.

; García-Ramírez, Alejandro

Polibotánica

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2024, N. 58 Pages 225 - 235

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract The whitefly Bemisia tabaci Genn. is a plant pest highly harmful to horticultural crops worldwide. A sustainable tactic for the management of this pest is the search for plant resistance. Wild tomatoes are a crucial source of genetic diversity and genes for resistance to biotic factors as pest incidence. The objective of this work was to evaluate 15 accessions of creole tomatoes in greenhouse for attraction and oviposition response of B. tabaci. In addition, to estimate the incidence and severity of begomovirus in a field trial. The Rosa pa’ak ez2 accession had the lowest number of adults (0.7 per cm2) and Socato uptl had the lowest preference for oviposition (0.8 eggs per cm2). In the field, the País ac and Rosa pa’ak ez2 accessions had significantly fewer adults on the foliage. For the incidence and severity symptoms, Socato uptl had 76.7% of plants with virus symptoms and severity of 2.2 (60 days after transplant) and 2.9 (75 days after transplant), respectively. The results showed variation in the tomato accessions in the attraction of adults, oviposition preference, and susceptibility to viruses transmitted by B. tabaci.

Resumen La mosquita blanca Bemisia tabaci Genn. es una plaga dañina a cultivos hortícolas a nivel mundial. Una de las tácticas sustentables para su manejo es la búsqueda de fuentes de resistencia a esta plaga. Los tomates silvestres son fuente importante de diversidad genética y en ellos se puede encontrar genes de resistencia a diversos factores bióticos, como la incidencia de plagas. El objetivo de este trabajo fue evaluar bajo condiciones de invernadero 15 accesiones de tomates criollos, a la atracción y oviposición de B. tabaci. Además, de estimar la incidencia y severidad de begomovirus en campo. La accesión Rosa pa’ak ez2 tuvo menor atracción de adultos (0.7 adultos por cm2) y Socato uptl tuvo menor preferencia de oviposición (0.8 huevos cm2). En campo, las accesiones País ac y Rosa pa’ak ez2 tuvieron significativamente menor presencia de adultos en el follaje. Para incidencia y severidad de síntomas de virosis, Socato uptl tuvo el 76.7% de plantas con síntomas de virosis y una severidad de 2.2 a los 60 días después del trasplante y 2.9 a los 75 días después del trasplante. Los resultados evidenciaron variación en las accesiones de tomate a la atracción de adultos, preferencia de oviposición y susceptibilidad a virosis transmitida por B. tabaci.

https://doi.org/10.18387/polibotanica.58.16

PoSLemma: How Traditional Machine Learning and Linguistics Preprocessing Aid in Machine Generated Text Detection
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Jiménez, Diana

; Cardoso-Moreno, Marco A.

; Aguilar-Canto, Fernando

; Juárez-Gambino, Omar

; Calvo, Hiram

Computación y Sistemas

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dec 2023, Volume 27 N. 4 Pages 921 - 928

Abstract: En | Text: En | PDF: En

Abstract: With the release of several Large Language Models (LLMs) to the public, concerns have emerged regarding their ethical implications and potential misuse. This paper proposes an approach to address the need for technologies that can distinguish between text sequences generated by humans and those produced by LLMs. The proposed method leverages traditional Natural Language Processing (NLP) feature extraction techniques focusing on linguistic properties, and traditional Machine Learning (ML) methods like Logistic Regression and Support Vector Machines (SVMs). We also compare this approach with an ensemble of Long-Short Term Memory (LSTM) networks, each analyzing different paradigms of Part of Speech (PoS) taggings. Our traditional ML models achieved F1 scores of 0.80 and 0.72 in the respective analyzed tasks.

https://doi.org/10.13053/cys-27-4-4778

Madurez fisiológica en semillas de maíz (Zea mays L.) mediante marcadores morfológicos y el contenido de humedad
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Estrada-Urbina, Juan

; Cantú-López, Emmanuel

; Molina-Moreno, Juan Celestino

; Estrada-Gómez, Julio Arturo

Agronomía Mesoamericana

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dec 2023, Volume 34 N. 3 elocation 53269

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Introducción. La madurez fisiológica es la acumulación del máximo contenido de materia seca; inciden la línea de leche y la capa negra en la semilla de maíz, como factores morfológicos del grado de maduración. La línea de leche se relaciona con la solidificación del almidón, y la capa negra con el cese de la translocación de sustancias solubles de la planta hacia el grano. El contenido de humedad está relacionado con la madurez fisiológica y a la oportunidad de cosecha asociada con la máxima calidad. Objetivo. Determinar la madurez fisiológica de las semillas por medio de marcadores morfológicos y el contenido de humedad, y su relación con la calidad fisiológica. Materiales y métodos. El estudio se llevó a cabo en el Colegio de Postgraduados, Campus Montecillo en los meses de septiembre y octubre del 2021. Se realizaron muestreos semanales en mazorcas del cultivar experimental (Amarillo x V-54) F6, se tomaron semillas correspondientes a las áreas ápice, media y baja de la mazorca. En función del contenido de humedad se determinó la línea de leche, la capa negra, y la relación de estos factores con la calidad fisiológica (germinación y vigor, envejecimiento acelerado y prueba de frío). Resultados. El contenido de humedad de semillas maduras fue inferior al reportado en la literatura (35 %), también, se logró corroborar a nivel visual la madurez fisiológica por medio de la línea de leche y la capa negra; la germinación se incrementó conforme se avanzó en los muestreos con el menor contenido de humedad y, respecto al vigor, se detectó una mejor repuesta en el envejecimiento acelerado. Conclusiones. En la medida que el contenido de humedad disminuyó, la germinación incrementó. Los marcadores morfológicos permitieron determinar el tiempo en que la semilla de maíz alcanzó la madurez fisiológica, y con ello la máxima calidad.

Abstract Introduction. Physiological maturity is the accumulation of the maximum dry matter content, the milk line and the black layer affect the corn seed, as morphological factors of the degree of maturation. The milk line is related to the solidification of starch, and the black layer with the cessation of the translocation of soluble substances from the plant to the grain. The moisture content is related to the physiological maturity and the harvest opportunity associated with the maximum quality of the product. Objective. Determine seeds physiological maturity, through morphological markers and moisture content, and its physiological quality relationship. Materials and methods. The study was carried out at Colegio de Postgraduados, Campus Montecillo during the months of September-October, 2021. By weekly sampling cobs of experimental cv. (Amarillo × V-54A) F6 genotype, seeds from the apex were taken, middle section and basis. In function by its moisture content, the milk line, black layer, and the relationship of these factor with physiological quality (germination and vigor- accelerated aging and cold tests) were determined. Results. Moisture content was below than referred in literature (35 %), also, physiological maturity was defined visually by milk line and black layer; on the other hand, as sampling were done, there was an increase in seed germination with the less moisture content; what vigor refers, a better response was detected by accelerated aging test. Conclusions. As the moisture content decreased, germination increased. The morphological markers allowed to determine the time in which the maize seed reached the physiological maturity and with it, the maximum quality.

https://doi.org/10.15517/am.2023.53269

Bloqueo del plexo hipogástrico superior para manejo de dolor pélvico crónico no oncológico: efectividad y seguridad
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Yepes-Ríos, AF

; Puerta-Martínez, F

; Uribe-Moreno, M

; Felipe-García, A

; Bedoya, MA

Revista de la Sociedad Española del Dolor

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apr 2023, Volume 30 N. 2 Pages 109 - 114

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: Chronic pelvic pain is a common, disabling gynecological problem that affects patient's quality of life. Its prevalence is estimated to be up to 26.6 % worldwide and in 30 % of the cases there's no clear trigger. Within the analgesic management, the use of interventionism is proposed as an effective tool, for this reason the cases collected in the Colombian Institute of Pain (Incodol) are analyzed to determine the effectiveness and safety of the procedure. Materials and methods: In this retrospective descriptive study, 100 patients with superior hypogastric plexus block guided by fluoroscopy were analyzed. Data on pain perception and analgesic requirements were obtained at 0, 1, 3, and 6 months after the block, and complications such as bleeding, infection, neurological injury, persistent pain, and toxicity were recorded. Pain perception was analyzed using the generalized linear model with mixed effects for repeated measures. Results: All patients presented visceral pain with a mean baseline perception of 8.4 (SD = 1.5). The perceived pain presented a clinically relevant decrease (> 50 %) of 45 %, 36 % and 23 % for each period and the decrease in analgesic requirement at 1, 3 and 6 months was 20 %, 19 % and 9 % respectively; For the sixth month, the reduction of pain perception was statistically significant, being higher in those who reduced the need for analgesics (-5.2; 95 % CI: -6.7, -3.8). No complications were recorded. Conclusions: The statistically significant reduction at six months in the mean of perceived pain in patients with fluoroscopy-guided superior hypogastric plexus block is documented, without registering associated complications. It is considered beneficial in terms of pain reduction from the perspective of absolute points with respect to baseline VAS value. The safety results give rise to consider it as a complementary and/or rescue technique in selected populations.

RESUMEN Introducción: El dolor pélvico crónico es un problema ginecológico común, incapacitante y que afecta a la calidad de vida. Se estima la prevalencia hasta del 26,6 % a nivel mundial y en el 30 % de los casos no tienen un desencadenante claro. Dentro del manejo analgésico se propone el uso de intervencionismo como herramienta de control efectivo; para eso se analizan los casos recolectados en el Instituto Colombiano del Dolor (Incodol) con el objetivo de determinar la efectividad y la seguridad del procedimiento. Materiales y métodos: En este estudio retrospectivo descriptivo, se analizaron 100 pacientes a los que se les realizó bloqueo del plexo hipogástrico superior guiado por fluoroscopia. Se obtuvo datos de dolor percibido y requerimiento de analgésicos a los 0, 1, 3 y 6 meses después el bloqueo, y se registraron las complicaciones como sangrado, infección, lesión neurológica, dolor persistente y toxicidad. La percepción del dolor se analizó mediante el modelo lineal generalizado con efectos mixtos para medidas repetidas. Resultados: Todos los pacientes presentaron dolor de tipo visceral con una percepción media basal de 8,4 (SD = 1,5). El dolor percibido presentó disminución clínicamente relevante (> 50 %) del 45 %, 36 % y 23 % para cada periodo y el descenso del requerimiento analgésico a los 1, 3 y 6 meses fueron de 20 %, 19 % y 9 %, respectivamente. Para el sexto mes percepción del dolor fue estadísticamente significativa, siendo mayor en quienes disminuyeron el requerimiento de analgésicos (-5,2; IC 95 %: -6,7, -3,8). No se registraron complicaciones. Conclusiones: Se documenta la reducción estadísticamente significativa a los seis meses en la media del dolor percibido en pacientes con bloqueo del plexo hipogástrico superior guiado por fluoroscopia, sin registrarse complicaciones asociadas. Se considera benéfico en términos de reducción del dolor desde la perspectiva de puntos absolutos con respecto al valor basal de EVA. Los resultados de seguridad dan pie para considerarlo como técnica complementaria y/o de rescate en poblaciones seleccionadas.

https://doi.org/10.20986/resed.2023.4038/2022

10.

Green chemistry synthesis and structural and optical study of Dy2(CO3)3→Dy2O3 transition
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Portillo Moreno, O.

; Chávez Portillo, M.

; Juarez Santiesteban, H.

; Alvarado Pulidoc, J.

; Ramos Reynoso, Y.

; Serrano de la Rosa, L.

Revista mexicana de física

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apr 2023, Volume 69 N. 2

Abstract: En | Text: En | PDF: En

Abstract This paper presents preliminary results of D y 2 C O 3 3 → D y 2 O 3 transition have been successfully obtained by Chemical Bath Deposition technical and subsequent thermal annealing temperature at ∼ 60 0 ∘ C. Two different temperatures of ∼ 2 0 ∘ C and ∼ 9 0 ∘ C ± 2 ∘ C are chosen to carry out the nanocrystalline growth. The crystalline phase is investigated by X-Ray Diffraction (XRD) and some optical properties; Transmittance, Reflectivity, Normalized Absorbance, real (n) and imaginary (k) parts refractive index. The crystalline phase of these inorganic nanomaterials for D y 2 C O 3 3 is orthorhombic phase, while for D y 2 O 3 it is cubic. Grain size average values located at ranged 2.8 - 3.4 n m for D y 2 C O 3 3 and ∼ 6.5 - 9.6 n m for D y 2 O 3. Vibrational modes are identified by Raman spectroscopy, modes at ∼ 150 - 1800 c m - 1 frequency range assigned to internal vibrations of C O 3 2 - ion: v 1 - - symmetric stretching ∼ 1098 c m - 1 V 3-asymmetric - C - O stretching situated at ∼ 1063 c m - 1, were observed corresponding to orthorhombic crystalline phase. The F g + A g and A 1 g modes, corresponding to cubic phase D y 2 O 3. Absorption measurement were assigned to the transitions from ground state 6 H 15 / 2 ) to different excited states such as 4 I 13 / 2 → 4 F 7 / 2 , 4 I 15 / 2 , 6 F 3 / 2 , 6 F 5 / 2 , 6 F 7 / 2 → 6 H 5 / 2 , 6 F 9 / 2 → 6 H 7 / 2 , 6 F 11 / 2 → 6 H 9 / 2 and 6 H 11 / 2 of D y 3 + cation. Tauc’s plot reveals band gap situated at range ∼ 4.66 - 5.17 e V for D y 2 C O 3 3 and ∼ 4.26 - 4.80 e V for D y 2 O 3 respectively.

https://doi.org/10.31349/revmexfis.69.021302

11.

Predictors of Trypanosoma cruzi PCR positivity in patients with chronic Chagas disease
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de Lima, Ana Carolina Bastos

; Mendes, Veronica Gonçalves

; Ferreira, Roberto Rodrigues

; Nisimura, Lindice Mitie

; Horita, Samuel Iwao Maia

; Veloso, Henrique H

; Costa, Andréa R

; da Silva, Gilberto Marcelo S

; Sangenis, Luiz Henrique C

; Holanda, Marcelo T

; Rimolo, Lorena

; Cunha, Ademir B

; Garzoni, Luciana Ribeiro

; Hasslocher-Moreno, Alejandro Marcel

; Mediano, Mauro Felippe F

; Moreira, Otacílio da Cruz

; Britto, Constança

; Saraiva, Roberto M

Memórias do Instituto Oswaldo Cruz

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2023, Volume 118 elocation e230115

Abstract: En | Text: En | PDF: En

BACKGROUND A positive Trypanosoma cruzi polymerase chain reaction (PCR) is associated with a worse prognosis in patients with chronic Chagas disease (CD). OBJECTIVES To study the association of clinical, electrocardiographic, and echocardiographic characteristics and biomarker blood levels with positive T. cruzi PCR in chronic CD. METHODS This is a single-centre observational cross-sectional study. Positive T. cruzi PCR association with clinical, electrocardiographic, and echocardiographic characteristics, and biomarker blood levels were studied by logistic regression analysis. p values < 0.05 were considered significant. FINDINGS Among 333 patients with chronic CD (56.4% men; 62 ± 10 years), T. cruzi PCR was positive in 41.1%. Stepwise multivariate logistic regression showed an independent association between positive T. cruzi PCR and diabetes mellitus {odds ratio (OR) 0.53 [95% confidence interval (CI) 0.30-0.93]; p = 0.03}, right bundle branch block [OR 1.78 (95% CI 1.09-2.89); p = 0.02], and history of trypanocidal treatment [OR 0.13 (95% CI 0.04-0.38); p = 0.0002]. Among patients with a history of trypanocidal treatment (n = 39), only four (10%) patients had a positive T. cruzi PCR. MAIN CONCLUSIONS Among several studied parameters, only diabetes mellitus, right bundle branch block, and history of trypanocidal treatment showed an independent association with positive T. cruzi PCR. History of trypanocidal treatment was a strong protective factor against a positive T. cruzi PCR. (PCR . (CD) clinical electrocardiographic T singlecentre single centre crosssectional cross sectional analysis 005 0 05 0.0 significant 33 56.4% 564 56 4 (56.4 men 6 1 years, years , years) 411 41 41.1% odds OR (OR 053 53 0.5 95% 95 [95 (CI 0.300.93 030093 0.30 0.93 30 93 0.30-0.93] 0.03, 003 0.03 03 0.03} 178 78 1.7 (95 1.092.89 109289 1.09 2.89 09 2 89 1.09-2.89) 0.02, 002 0.02 02 0.02] 013 13 0.1 0.040.38 004038 0.04 0.38 04 38 0.04-0.38) 0.0002. 00002 0.0002 0002 0.0002] n 39, 39 39) 10% (10% parameters (CD 00 0. 3 56.4 5 (56. 41.1 9 [9 300 0.300.9 03009 030 0.3 093 0.9 0.30-0.93 17 7 1. (9 092 1.092.8 10928 109 1.0 289 2.8 8 1.09-2.89 01 040 0.040.3 00403 004 038 0.04-0.38 0000 0.000 000 (10 56. (56 41. [ 0.300. 0300 0.30-0.9 ( 1.092. 1092 28 2. 1.09-2.8 0.040. 0040 0.04-0.3 0.00 (1 (5 0.300 0.30-0. 1.092 1.09-2. 0.040 0.04-0. 0.30-0 1.09-2 0.04-0 0.30- 1.09- 0.04-

https://doi.org/10.1590/0074-02760230115

12.

Acupuntura no alívio da dor osteomuscular e a melhora na funcionalidade na pessoa idosa: estudo quase experimental idosa
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Lamego, Fabio Ricardo Dutra

; Santo, Fátima Helena do Espírito

; Ribeiro, Maria de Nazaré de Souza

; Barbosa, Gleyce Moreno

; Pimenta, Almir Campos

; Souza, Michelle Freitas de

Revista Brasileira de Geriatria e Gerontologia

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2023, Volume 26 elocation e230147

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo Avaliar os efeitos da acupuntura no alívio da dor osteomuscular em pessoas idosas e a possibilidade de melhora da funcionalidade para as atividades básicas de vida diária. Método Estudo quase experimental, com avaliação antes e depois da intervenção utilizando a Escala Visual Analógica e o Índice de Katz. Amostra por conveniência, constituída de 31 pessoas idosas. O período de intervenção comportou quatro sessões de atendimentos semanais. A intervenção com acupuntura abordou um protocolo de tratamento sistêmico por intermédio de cinco pares de pontos: IG4 (Hegu), F3 (Taichong), E36 (Zusanli), PC6 (Neiguan) e BP6 (Sanyinjiao). Resultados 100% (31) informando sentir dor, sendo 64,52% (20) em intensidade moderada (3–7); 25,81% (8) dor intensa (8–10); e 9,68% (3) dor leve (0–2). O protocolo de tratamento mostrou-se positivo em 4 sessões, com redução da dor ao grau leve, e média geral reduzida abaixo de 2 no score. A análise dos resultados da Escala Visual Analógica e os do índice de Katz, mostrou possibilidades do uso da acupuntura no alívio da dor osteomuscular e na melhora da funcionalidade da pessoa idosa. Conclusão O uso da técnica de acupuntura sistêmica apontou resultados satisfatórios no alívio da dor osteomuscular e na melhoria da funcionalidade para as atividades básicas de vida diária da pessoa idosa. experimental Katz conveniência 3 semanais pontos IG Hegu, Hegu , (Hegu) F Taichong, Taichong (Taichong) E E3 Zusanli, Zusanli (Zusanli) PC Neiguan (Neiguan BP Sanyinjiao. Sanyinjiao . (Sanyinjiao) 100 (31 6452 64 52 64,52 20 (20 3–7 37 7 (3–7) 2581 25 81 25,81 8 (8 8–10 810 10 (8–10) 968 9 68 9,68 (3 0–2. 02 0–2 0 (0–2) mostrouse se score idosa (Hegu (Taichong (Zusanli (Sanyinjiao 645 6 5 64,5 (2 3– (3–7 258 25,8 ( 8–1 1 (8–10 96 9,6 0– (0–2 64, (3– 25, 8– (8–1 9, (0– (8– (0

Abstract Objective To assess the effects of acupuncture on the relief of osteomuscular pain in older adults and the potential improvement in functionality for activities of daily living. Method A quasi-experimental study, with pre- and post-intervention assessment using the Visual Analog Scale and the Katz Index. Convenience sample comprising 31 older adults. The intervention period consisted of four weekly treatment sessions. Acupuncture intervention targeted a systemic treatment protocol utilizing five pairs of acupoints: LI4 (Hegu), LIV3 (Taichong), ST36 (Zusanli), PC6 (Neiguan), and SP6 (Sanyinjiao). Results 100% (31) reported experiencing pain, with 64.52% (20) reporting moderate pain (3-7), 25.81% (8) reporting severe pain (8-10), and 9.68% (3) reporting mild pain (0-2). The treatment protocol demonstrated positive outcomes after 4 sessions, with a reduction of pain to a mild degree and an overall average score reduced below 2. The analysis of results from the Visual Analog Scale and the Katz Index showed potential for the use of acupuncture in relieving osteomuscular pain and improving the functionality of the older adult. Conclusion The use of systemic acupuncture techniques yielded satisfactory results in the relief of osteomuscular pain and the enhancement of functionality for activities of daily living of the older adult. quasiexperimental quasi experimental study pre postintervention post 3 sessions acupoints LI Hegu, Hegu , (Hegu) LIV Taichong, Taichong (Taichong) ST ST3 Zusanli, Zusanli (Zusanli) PC Neiguan, Neiguan (Neiguan) SP Sanyinjiao. Sanyinjiao . (Sanyinjiao) 100 (31 6452 64 52 64.52 20 (20 37, 37 7 (3-7) 2581 25 81 25.81 8 (8 810, 810 10 (8-10) 968 9 68 9.68 (3 02. 02 0 2 (0-2) adult (Hegu (Taichong (Zusanli (Neiguan (Sanyinjiao 645 6 5 64.5 (2 (3-7 258 25.8 ( 1 (8-10 96 9.6 (0-2 64. (3- 25. (8-1 9. (0- (8- (0

https://doi.org/10.1590/1981-22562023026.230147.pt

13.

Changes in mental health of children and young people in residential care: outcomes and associated factors
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González-García, Carla

; Vassiliadis, Elli

; Moreno-Manso, Juan M

; Alcántara, Mavi

; del Valle, Jorge F

; Bravo, Amaia

Psychosocial Intervention

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2023, Volume 32 N. 1 Pages 11 - 19

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Several studies have evidenced that children in out-of-home care (OOHC), including foster family care and residential care, reveal high levels of mental health disorders (ranging from 40% to 88%). This study examines the outcomes in mental health reported by key residential workers in a group of children and youth (N = 492) between 8-17 years old who were in residential child care (RCC) in Spain. The research also aims to explore the relationship between mental health outcomes and the provision of mental health services (i.e., receiving any mental health treatment) as well as the influence of child, family, and placement factors. The design of this study includes two measures: a baseline (T1) and a follow-up two years later (T2). The results indicated that 29.9% of young people enjoyed sustained mental health; 26% meaningful improvement in their mental health; 23.5% meaningful deterioration; and the remaining 20.5% showed no meaningful change. One of the main findings was that receiving mental health treatment had a significant impact on mental health outcomes. It is crucial to establish protocols and systematic detection tools to assess mental health and ensure detection and referral to proper treatment.

RESUMEN La investigación en el ámbito de la protección a la infancia ha destacado la presencia de un alto porcentaje de niños, niñas y adolescentes (NNA) en acogimiento residencial y familiar con trastornos de salud mental (entre el 40% y el 88%). Este estudio tiene como objetivo examinar los cambios experimentados en la salud mental de los NNA durante el proceso de acogida según informan sus educadores de referencia en un grupo de 492 NNA entre 8-17 años que se encontraban en hogares de protección en España. El estudio también tiene como objetivo explorar la relación entre los resultados en salud mental y el tratamiento recibido desde diferentes servicios de salud mental, además de la influencia que puedan ejercer factores del NNA, su familia o el proceso de protección. El diseño del estudio se basa en dos medidas: línea base (T1) y seguimiento dos años después (T2). Los resultados indican que el 29.9% de los NNA mantenía una buena salud mental en las dos medidas, 26% manifestaron una mejora significativa partiendo de niveles clínicos, 23.5% manifestaron un deterioro significativo y el 20.5% no mostraron cambios significativos, manteniendo niveles clínicos en ambas medidas. Una de las principales conclusiones fue que estar recibiendo o no tratamiento en salud mental resultó ser un factor clave en la evolución de los NNA. Por tanto, resulta crucial establecer sistemas de detección de problemas de salud mental en esta población con el fin de derivar precozmente a tratamientos adecuados.

https://doi.org/10.5093/pi2022a16

14.

Adenitis cervical unilateral por Staphylococcus aereus en un paciente adulto. Presentación de un caso
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Verde-Sánchez, Laura

; Muñoz-Guerra, Mario F

; Capote-Moreno, Ana

; Castillo-Gázmez, Lidia

; Brabyn, Philip

; Naval-Gías, Luis

Revista Española de Cirugía Oral y Maxilofacial

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sep 2022, Volume 44 N. 3 Pages 126 - 129

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Due to the fact that in more than 50 % of cases the appearance of adenopathy in patients over 40 years of age is of probable tumor etiology, the management of cervical masses in adult patients should include the necessary tests to rule out a malignant process. The differential diagnosis is fundamental in this type of lesions, identifying the risk factors, symptoms and signs that orient towards the etiology (congenital, neoplastic, inflammatory or infectious). As concerns cervical adenopathies of infectious cause, they are more frequent in children. However, adults also usually develop them as a consequence of oral or pharyngotonsillar pathology. In these cases, a rapid response to empirical treatment is observed. However, if there is no resolution of the picture with such treatment within 2-3 weeks, it is necessary to extend the study by means of complementary tests. We present a rare case of suppurative lymphadenitis due to Staphylococcus aereus in the cervical region in a 45-year-old woman who presented to the emergency department with a cervical mass.

RESUMEN Debido a que en más del 50 % de los casos la aparición de adenopatías en mayores de 40 años es de probable etiología tumoral, el manejo de masas cervicales del paciente adulto debe incluir las pruebas necesarias para descartar un proceso maligno. El diagnóstico diferencial es fundamental en este tipo de lesiones, identificando los factores de riesgo, síntomas y signos que orienten hacia la etiología (congénita, neoplásica, inflamatoria o infecciosa). Por lo que se refiere a las adenopatías cervicales de causa infecciosa son más frecuentes en los niños. Sin embargo, habitualmente los adultos también las desarrollan como consecuencia de patología oral o faringoamigdalar. En estos casos, se observa una rápida respuesta ante el tratamiento empírico. No obstante, si no se produce la resolución del cuadro con dicho tratamiento en 2-3 semanas, es necesaria la ampliación del estudio mediante pruebas complementarias. Se presenta un caso clínico infrecuente en la literatura de lindadenitis supurada por Staphylococcus aereus en región cervical, en una mujer de 45 años que acudió al servicio de urgencias con clínica de masa cervical a estudio.

https://doi.org/10.20986/recom.2022.1405/2022

15.

Distribución de agregados y carbono orgánico asociado de los suelos con relación a diferentes tipos de usos de suelo y profundidades
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Barrales-Brito, Edgar

; Paz-Pellat, Fernando

; Velázquez-Rodríguez, Alma S.

; Hidalgo-Moreno, Claudia

; Etchevers-Barra, Jorge Dionisio

Terra Latinoamericana

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dec 2021, Volume 39 elocation e1318

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Summary: The aggregates distribution (masses) in different land uses and depths allows characterizing their structural stability and understanding the changes in the dynamics of carbon and mass distribution depending on the aggregates size. To model the distribution and mass of aggregates related to depth for different land uses, seven land uses were analyzed: Abies forest (BAr), Cupressus forest (BCr), Quercus forest (BQr), Abies forest with forest f ire (BAq), Quercus secondary forest (Bs), grassland (Pz) and agriculture with traditional tillage (Agt), all located on Mount Tlaloc in Texcoco, State of Mexico. Additionally, a conservation agriculture site (Agc) was selected in the lower part of Mount Tlaloc. To develop a general model, we started from the analysis of the patterns of the distribution of the accumulated mass (M acum) and accumulated carbon (C acum) in relation to the size of the aggregates, for different soil depths in each land use. Based on the adjusted mathematical models, a general model of n order kinetics was proposed as a cause for the observed solutions. The statistical adjustments were excellent (R2 > 0.99, generally).

Resumen: La distribución de los agregados (masas) en diferentes usos de suelo y profundidades permite caracterizar su estabilidad estructural y comprender los cambios de la dinámica de la distribución del carbono y masa en función del tamaño de los agregados. Para modelar la distribución y masa de los agregados a diferentes profundidades para diferentes usos de suelo se analizaron siete usos de suelo: bosque de Abies (BAr), bosque de Cupressus (BCr), bosque de Quercus (BQr), bosque de Abies con incendio forestal (BAq), bosque secundario o acahual de Quercus (Bs), pastizal (Pz) y agrícola con labranza tradicional (Agt), todos ellos localizados en el monte Tláloc en Texcoco, Estado de México. Adicionalmente se seleccionó un sitio de agricultura de conservación (Agc) en la parte baja del monte Tláloc. Para desarrollar un modelo general, se partió del análisis de los patrones de la distribución de la masa acumulada (M acum) y carbono acumulado (C acum) con relación a las dimensiones de los agregados, para diferentes profundidades en cada uso del suelo. Con base en los modelos matemáticos ajustados, se planteó un modelo general de cinética de orden n como causa para las soluciones observadas. Los ajustes estadísticos fueron excelentes (R2 > 0.99, generalmente).

https://doi.org/10.28940/terra.v39i0.1318 32 downloads

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