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RESUMO Contexto: Em estudos observacionais sobre a síndrome do desconforto respiratório agudo, sugeriu-se que a driving pressure é o principal fator de lesão pulmonar induzida por ventilador e de mortalidade. Não está claro se uma estratégia de limitação da driving pressure pode melhorar os desfechos clínicos. Objetivo: Descrever o protocolo e o plano de análise estatística que serão usados para testar se uma estratégia de limitação da driving pressure envolvendo a titulação da pressão positiva expiratória final de acordo com a melhor complacência respiratória e a redução do volume corrente é superior a uma estratégia padrão envolvendo o uso da tabela de pressão positiva expiratória final baixa do protocolo ARDSNet, em termos de aumento do número de dias sem ventilador em pacientes com síndrome do desconforto respiratório agudo devido à pneumonia adquirida na comunidade. Métodos: O estudo STAMINA (ventilator STrAtegy for coMmunIty acquired pNeumoniA) é randomizado, multicêntrico e aberto e compara uma estratégia de limitação da driving pressure com a tabela de pressão positiva expiratória final baixa do protocolo ARDSnet em pacientes com síndrome do desconforto respiratório agudo moderada a grave devido à pneumonia adquirida na comunidade internados em unidades de terapia intensiva. Esperamos recrutar 500 pacientes de 20 unidades de terapia intensiva brasileiras e duas colombianas. Eles serão randomizados para um grupo da estratégia de limitação da driving pressure ou para um grupo de estratégia padrão usando a tabela de pressão positiva expiratória final baixa do protocolo ARDSnet. No grupo da estratégia de limitação da driving pressure, a pressão positiva expiratória final será titulada de acordo com a melhor complacência do sistema respiratório. Desfechos: O desfecho primário é o número de dias sem ventilador em 28 dias. Os desfechos secundários são a mortalidade hospitalar e na unidade de terapia intensiva e a necessidade de terapias de resgate, como suporte de vida extracorpóreo, manobras de recrutamento e óxido nítrico inalado. Conclusão: O STAMINA foi projetado para fornecer evidências sobre se uma estratégia de limitação da driving pressure é superior à estratégia da tabela de pressão positiva expiratória final baixa do protocolo ARDSnet para aumentar o número de dias sem ventilador em 28 dias em pacientes com síndrome do desconforto respiratório agudo moderada a grave. Aqui, descrevemos a justificativa, o desenho e o status do estudo. Contexto sugeriuse sugeriu clínicos Objetivo ARDSNet Métodos ventilator pNeumoniA randomizado 50 2 colombianas Desfechos resgate extracorpóreo inalado Conclusão Aqui justificativa 5

ABSTRACT Background: Driving pressure has been suggested to be the main driver of ventilator-induced lung injury and mortality in observational studies of acute respiratory distress syndrome. Whether a driving pressure-limiting strategy can improve clinical outcomes is unclear. Objective: To describe the protocol and statistical analysis plan that will be used to test whether a driving pressure-limiting strategy including positive end-expiratory pressure titration according to the best respiratory compliance and reduction in tidal volume is superior to a standard strategy involving the use of the ARDSNet low-positive end-expiratory pressure table in terms of increasing the number of ventilator-free days in patients with acute respiratory distress syndrome due to community-acquired pneumonia. Methods: The ventilator STrAtegy for coMmunIty acquired pNeumoniA (STAMINA) study is a randomized, multicenter, open-label trial that compares a driving pressure-limiting strategy to the ARDSnet low-positive end-expiratory pressure table in patients with moderate-to-severe acute respiratory distress syndrome due to community-acquired pneumonia admitted to intensive care units. We expect to recruit 500 patients from 20 Brazilian and 2 Colombian intensive care units. They will be randomized to a driving pressure-limiting strategy group or to a standard strategy using the ARDSNet low-positive end-expiratory pressure table. In the driving pressure-limiting strategy group, positive end-expiratory pressure will be titrated according to the best respiratory system compliance. Outcomes: The primary outcome is the number of ventilator-free days within 28 days. The secondary outcomes are in-hospital and intensive care unit mortality and the need for rescue therapies such as extracorporeal life support, recruitment maneuvers and inhaled nitric oxide. Conclusion: STAMINA is designed to provide evidence on whether a driving pressure-limiting strategy is superior to the ARDSNet low-positive end-expiratory pressure table strategy for increasing the number of ventilator-free days within 28 days in patients with moderate-to-severe acute respiratory distress syndrome. Here, we describe the rationale, design and status of the trial. Background ventilatorinduced induced pressurelimiting limiting unclear Objective endexpiratory end expiratory lowpositive low ventilatorfree free communityacquired community Methods (STAMINA multicenter openlabel open label moderatetosevere moderate severe units 50 Outcomes inhospital hospital support oxide Conclusion Here rationale 5

https://doi.org/10.62675/2965-2774.20240210-en

Comparison of supervised machine learning and variable selection methods for body weight prediction of growth pigs using image processing data
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Carrara, Eula Regina

; Oliveira, Polliany da Costa Santos

; Dias, Layla Cristien de Cássia Miranda

; Costa, Weverton Gomes da

; Conceição, Aline Rabello

; Braga, Pedro Henrique Silva

; Chizzotti, Mario Luiz

; Veroneze, Renata

; Schultz, Erica Beatriz

Revista Brasileira de Zootecnia

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2024, Volume 53 elocation e20240001

Abstract: En | Text: En | PDF: En

ABSTRACT This research aimed to compare statistical methods (random forest, RIDGE, LASSO, and elastic net regression) for the prediction of body weight in purebred and crossbred pigs reared in Brazil. This prediction was based on dorsal-view images obtained from video image processing. The study involved 69 animals belonging to breeds such as Large White, Piau, Duroc × Large White, and Piau × Large White. The data collection spanned 144 days, with measurements taken at approximately 20-day intervals, totaling eight measurements for each animal throughout their growth stages. Image acquisition was carried out in individual pens using an Intel RealSense Depth D435 digital camera. The features back area, back perimeter, back width, and body depth were extracted from the images. Pearson’s correlation analysis was conducted to assess the relationship between live weight and these features. The dataset was randomly divided into a training dataset (65%) and a test dataset (35%), and model training was performed by five-fold cross-validation balanced according to the growth stage, which was divided into three groups. This procedure was repeated 100 times, and the resulting metrics were taken as the average of the 100 repetitions. Although with a slight difference, the random forest method outperformed the others with the highest average R2 value (0.87), as well as the lowest average RMSE (14.32) and average MAE (10.13) values. Consequently, the random forest algorithm proved to be the most effective in predicting body weight. The back area, back width, and back perimeter were the most important variables in the model. RIDGE LASSO regression Brazil dorsalview dorsal view processing 6 White 14 days 20day day 20 intervals stages D D43 camera area width Pearsons Pearson s 65% 65 (65% 35%, 35 35% , (35%) fivefold five fold crossvalidation cross validation stage groups 10 times repetitions difference R 0.87, 087 0.87 0 87 (0.87) 14.32 1432 32 (14.32 10.13 1013 13 (10.13 values Consequently 1 2 D4 (65 3 (35% 08 0.8 8 (0.87 14.3 143 (14.3 10.1 101 (10.1 (6 (35 0. (0.8 14. (14. 10. (10. ( (3 (0. (14 (10 (0 (1

https://doi.org/10.37496/rbz5320240001

Prenatal and perinatal care in Governador Valadares, Minas Gerais state, Brazil
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Defilipo, Érica Cesário

; Chagas, Paula Silva de Carvalho

; Silva, Rívia Miranda da

; Costa, Quézia Beatriz de Souza

; Guilherme, Mariana Cristina Oliveira

; Ferreira, Mariana Cristina Palermo

; Ribeiro, Luiz Cláudio

Fisioterapia em Movimento

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2022, Volume 35 N. spe elocation e35608

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: O acompanhamento pré-natal e as condutas adotadas durante o parto são essenciais para garantir o bom desenvolvimento da gestação, prevenir complicações e proporcionar um parto saudável, sem impacto na saúde da puérpera e do recém-nascido. Objetivo: Analisar a assistência pré-natal e perinatal oferecida em Governador Valadares, Minas Gerais, e verificar se há associação entre a adequação do pré-natal e os fatores socioeconômicos, demográficos, comportamentais e reprodutivos. Métodos: Estudo transversal com base de dados pré-existente. Para a análise da adequação do pré-natal foram utilizados três critérios: 1) início até 16ª semana e número mínimo de consultas de acordo com a idade gestacional; 2) práticas dos profissionais nas consultas de pré-natal; 3) orientações oferecidas às gestantes pelos profissionais. Para a análise dos dados foi utilizada regressão logística multivariada. Resultados: Participaram do estudo 437 puérperas. A assistência pré-natal foi considerada adequada para 72,5%, 93,1% e 50,1% das puérperas, considerando os critérios 1, 2 e 3, respectivamente. As gestantes que apresentaram maior chance de terem o pré-natal inadequado, com relação ao critério 1, foram as com menor escolaridade (RC = 1,68; p = 0,046), que não possuíam companheiro (RC = 2,18; p = 0,002), que não trabalharam durante a gestação (RC = 2,18; p = 0,003) e as que não planejaram a gravidez (RC = 1,76; p = 0,023). Com relação à assistência perinatal, a presença de acompanhante e contato pele a pele foram apropriados, mas a amamentação na primeira hora de vida foi inadequada. Conclusão: Observou-se a necessidade de aprimorar as orientações fornecidas pelos profissionais e incluir a amamentação na primeira hora de vida. Os resultados podem contribuir para otimizar os serviços de saúde materno-infantil em Governador Valadares.

Abstract Introduction: Prenatal care and the procedures adopted during childbirth are essential to ensure a healthy pregnancy and delivery and prevent complications, without affecting the health of the mother and newborn. Objective: To analyze the prenatal and perinatal care provided in Governador Valadares, Minas Gerais state, Brazil, and to determine whether there is an association between adequate prenatal care and socioeconomic, demographic, behavioral and reproductive factors. Methods: Cross-sectional study with a pre-existing database. The adequacy of prenatal care was analyzed based on three criteria: 1) onset up to the 16th week and a minimum number of checkups according to gestational age; 2) professional practices during prenatal checkups; 3) counseling given to the pregnant women by healthcare professionals. Multivariate logistic regression was used for data analysis. Results: Participants were 437 postpartum women. Prenatal care was considered adequate for 72.5, 93.1 and 50.1% of the participants based on criteria 1, 2 and 3, respectively. The pregnant women who were most likely to receive inadequate prenatal care in relation to criterion 1 were those with the lowest schooling level (OR = 1.68; p = 0.046), who were single (OR = 2.18; p = 0.002), did not work during their pregnancy (OR = 2.18; p = 0.003) and whose pregnancy was unplanned (OR = 1.76; p = 0.023). With respect to perinatal care, the presence of a birth companion and skin-to-skin contact were adequate, but breastfeeding in the first hour of life was not. Conclusion: There is a need to improve the counseling provided by healthcare professionals and include breastfeeding in the first hour of life. The results could contribute to optimizing maternal and child health services in Governador Valadares.

https://doi.org/10.1590/fm.2022.35608

Factors associated with premature birth: a case-control study
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Defilipo, Érica Cesário

; Chagas, Paula Silva de Carvalho

; Drumond, Carolyne de Miranda

; Ribeiro, Luiz Cláudio

Revista Paulista de Pediatria

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2022, Volume 40 elocation e2020486

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Analisar os fatores socioeconômicos, demográficos, ambientais, reprodutivos, comportamentais e de assistência à saúde associados à prematuridade. Métodos: Estudo caso-controle, sendo o grupo caso composto de prematuros e o grupo controle, de nascidos vivos a termo. Cada caso foi pareado com dois controles, de acordo com o sexo e a data de nascimento. Foram realizadas entrevistas com as puérperas e análise de prontuários. Para análise dos dados, foi utilizada regressão logística, seguindo a ordem hierárquica de entrada dos blocos. Resultados: Participaram 221 nascidos vivos no grupo caso e 442 no grupo controle. Após análise ajustada para os demais fatores em estudo, as maiores chances de prematuridade foram associadas aos primeiros filhos (RC 1,96; IC95% 1,34–2,86; p=0,001), cujas mães possuíam maior renda (RC 2,08; IC95% 1,41–3,08; p<0,001), tiveram filho prematuro prévio (RC 3,98; IC95% 2,04–7,79; p<0,001), sofreram violência durante a gestação (RC 2,50; IC95% 1,31–4,78; p=0,005) e realizaram cesariana (RC 2,35; IC95% 1,63–3,38; p<0,001). Os nascidos vivos de mães que realizaram mais de seis consultas de pré-natal apresentaram menor chance de ser prematuros (RC 0,39; IC95% 0,26–0,58; p<0,001). Conclusões: Os fatores associados à maior chance de prematuridade foram: maior renda familiar, filho prematuro prévio, primiparidade, violência contra a gestante e cesariana. Ter realizado mais de seis consultas de pré-natal foi associado à menor chance de nascimento prematuro. A violência contra a gestante apresentou associação forte e consistente, permanecendo em todos os modelos finais, devendo servir de alerta para a população e os profissionais.

ABSTRACT Objective: To analyze the socioeconomic, demographic, environmental, reproductive, behavioral, and health-care factors associated with preterm birth. Methods: Case-control study, with case group composed of preterm infants and the control group by full term live births. Each case was paired with two controls according to sex and date of birth. Interviews were carried out with the mothers, as well as analysis of medical records. A logistic regression model was used for data analysis following the hierarchical order of entry of the blocks. Results: 221 live births were allocated in the case group and 442 in the control group. After analysis adjusted for other factors under study, the highest chances of prematurity were associated with being the first child (OR 1.96; 95%CI 1.34–2.86; p=0.001); mothers with the highest income (OR 2.08; 95%CI 1.41–3.08; p<0.001), mothers with previous preterm births (OR 3.98; 95%CI 2.04–7.79; p<0.001), mothers that suffered violence during pregnancy (OR 2.50; 95%CI 1.31–4.78; p=0.005) and underwent cesarean section (OR 2.35; 95%CI 1.63–3.38; p<0.001). Live births to mothers who had more than six prenatal consultations had a lower risk of prematurity (OR 0.39; 95%CI 0.26–0.58; p<0.001). Conclusions: The factors associated with a higher chance of prematurity were: higher family income, previous preterm child, primiparity, violence against pregnant women and cesarean section. Having attended more than six prenatal visits was associated with a lower chance of premature birth. Violence against pregnant women showed a strong and consistent association, remaining in all final models, and should serve as an alert for the population and professionals.

https://doi.org/10.1590/1984-0462/2022/40/2020486in

Repercussões da infodemia associada ao COVID-19 na saúde mental do idoso no Brasil
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Bezerra Cavalcante, Ricardo

; da Costa Carbogim, Fabio

; Fávero Bulgarelli, Alexandre

; Mello dos Santos, Camila

; Queiroz Ribeiro, Andréia

; Carvalho Pinto, Ione

; Machado Zacharias, Fabiana Costa

; Aparecida Fabriz, Luciana

; Moura de Oliveira, Deíse

; Toledo de Mendonça, Erica

; Ricardo Moreira, Tiago

; Miranda Machado, Richardson

; Ribeiro Bitencourt, Graziele

; Alfradique de Souza, Priscilla

; Fereira Santana, Rosimere

; Cabreira Panitz Cruz, Gylce Eloisa

; Rezende Freitas, Eduarda

; Salmazo da Silva, Henrique

; Viana Cruz, Fabiana

; Silva Fhon, Jack Roberto

; Shizuê Kitamura, Elisa

; Gonçalves Leite, Isabel Cristina

; Rodrigues Braz, Patricia

; Consolação dos Santos, Regina

; Prado Rocha, Flávia

; Aparecida Silva, Eveline

; Barreiros Tavares, Thais

; Duarte Martins, Jerusa Gonçalves

; Alves de Araújo Püschel, Vilanice

Revista Cubana de Información en Ciencias de la Salud

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2022, Volume 33 elocation e1871

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO: O fenômeno denominado infodemia refere-se ao aumento do volume informacional sobre um tema em específico, que se multiplica rapidamente em um curto período de tempo, e tem-se destacado frente ao contexto da crise sanitária desencadeada pela pandemia de COVID-19. O excesso de informações pode suscitar sentimentos de medo, ansiedade, estresse e outras condições de sofrimento mental. O estudo tem como objetivo descrever o perfil de exposição a informações sobre COVID-19 e suas repercussões na saúde mental de idosos brasileiros. Trata-se de um estudo transversal realizado com 1924 idosos brasileiros. Coletaram-se dados por meio de web-based survey enviada aos idosos por redes sociais e e-mail, no período de julho a outubro de 2020. Os resultados da análise descritiva dos dados demonstram que a maioria dos idosos apresentou idade entre 60 e 69 anos (69,02%), é do sexo feminino (71,26%), casados (53,79%) e de cor branca (75,57%). Cerca de 21,67% (n = 417) concluíram a graduação, 19,75% (380) concluíram especialização e 16,63% (320) concluíram mestrado ou doutorado. Foram reportados como fontes frequentes de exposição às notícias ou informações sobre a COVID-19, a televisão 862 (44,80%) e as redes sociais 651 (33,84%). Os participantes assinalaram que a televisão (46,47%; n = 872), as redes sociais (30,81%; n = 575) e o rádio (14,48%; 251) os afetavam psicológica e/ou fisicamente. Receber notícias falsas sobre a COVID-19 pela televisão (n = 482; 19,8%) e pelas redes sociais (n = 415; 21,5%) repercutiu, principalmente, estresse e medo. As informações disseminadas contribuem para conscientização, mas, também, afetam física e/ou psicologicamente muitos idosos, principalmente gerando medo e estresse.

ABSTRACT The phenomenon called infodemia refers to the increase in the volume of information on a specific topic, which multiplies rapidly in a short period of time, and has stood out in the context of the health crisis triggered by the COVID-19 pandemic. Too much information can trigger feelings of fear, anxiety, stress, and other conditions of mental distress. The study aims to describe the profile of exposure to information about COVID-19 and its repercussions on the mental health of elderly Brazilians. This is a cross-sectional study carried out with 1924 elderly Brazilians. Data were collected through a web-based survey sent to the elderly via social networks and email, from July to October 2020. The results of the descriptive analysis of the data show that most of the elderly were aged between 60 and 69 years (69.02%), female (71.26%), married (53.79%) and white (75.57%). About 21.67% (n = 417) concluded their graduation, 19.75% (380) concluded their specialization and 16.63% (320) concluded their master's or doctoral degrees. Television 862 (44.80%) and social networks 651 (33.84%) were reported as frequent sources of exposure to news or information about COVID-19. Participants indicated that television (46.47%; n = 872), social networks (30.81%; n = 575) and radio (14.48%; 251) affected them psychologically and/or physically. Receiving fake news about COVID-19 on television (n = 482; 19.8%) and on social media (n = 415; 21.5%) mainly resulted in stress and fear. The disseminated information contributes to awareness, but also affects physically and/or psychologically many elderly people, mainly generating fear and stress.

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Clinical correlates of social cognition after an ischemic stroke: preliminary findings
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Souza, Maria de Fátima Dias de

; Cardoso, Maíra Glória de Freitas

; Vieira, Érica Leandro Marciano

; Rocha, Natália Pessoa

; Vieira, Talita Hélen Ferreira e

; Pessoa, Alberlúcio Esquirio

; Pedroso, Vinicius Sousa Pietra

; Rachid, Milene Alvarenga

; Souza, Leonardo Cruz de

; Teixeira, Antônio Lúcio

; Mourão, Aline Mansueto

; Miranda, Aline Silva de

Dementia & Neuropsychologia

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apr 2021, Volume 15 N. 2 Pages 223 - 229

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO. A co-ocorrência de distúrbios comportamentais e comprometimento cognitivo pós-acidente vascular cerebral (AVC) é amplamente descrita na literatura. No entanto, os estudos geralmente não incluem a cognição social entre os domínios cognitivos avaliados. Objetivo: Investigar a potencial associação entre o reconhecimento da emoção facial, uma medida da cognição social, e os sintomas comportamentais e cognitivos na fase subaguda do AVC isquêmico. Métodos: Pacientes internados em uma Unidade de AVC com AVC isquêmico foram acompanhados até 60 dias, quando foram avaliados com os seguintes instrumentos: Mini-Exame do Estado Mental (MEEM); Bateria de Avaliação Frontal (FAB); Teste de Memória Visual da Bateria Cognitiva Breve (VMT); Fluência Verbal Fonêmica (Teste F-A-S); Span de dígitos; Teste de Reconhecimento de Emoção Facial (FERT) e Escala Hospitalar de Ansiedade e Depressão (HADS). Um grupo controle constituído por 21 indivíduos saudáveis também foi submetido à mesma avaliação. Resultados: Dezoito pacientes com AVC isquêmico foram incluídos no presente estudo, apresentando idade, sexo e anos de escolaridade semelhantes aos do grupo controle. Os sintomas de depressão e déficits de memória episódica foram significativamente mais frequentes em pacientes com AVC. O reconhecimento da expressão de tristeza correlacionou-se positivamente com os níveis de ansiedade e depressão, ao passo que o reconhecimento da expressão de medo correlacionou-se negativamente com depressão no grupo de AVC. Conclusões: Após um AVC isquêmico, pacientes podem apresentar alterações de cognição social, especificamente de reconhecimento da emoção facial, em associação com sintomas comportamentais.

ABSTRACT. The co-occurrence of post-stroke behavioral disorders and cognitive impairment has been extensively investigated. However, studies usually do not include social cognition among the assessed cognitive domains. Objective: To investigate the potential association between facial emotion recognition, a measure of social cognition, and behavioral and cognitive symptoms in the subacute phase of ischemic stroke. Methods: Patients admitted to a Stroke Unit with ischemic stroke were followed up to 60 days. At this time point, they were evaluated with the following tools: Mini-Mental State Examination (MMSE); Frontal Assessment Battery (FAB); Visual Memory Test of the Brief Cognitive Battery (VMT); Phonemic Verbal Fluency (F-A-S Test); Digit Span; Facial Emotion Recognition Test (FERT) and Hospital Anxiety and Depression Scale (HADS). A control group composed of 21 healthy individuals also underwent the same evaluation. Results: Eighteen patients with ischemic stroke were enrolled in this study. They had similar age, sex and schooling years compared to controls. Depression symptoms and episodic memory deficits were significantly more frequent in patients compared to controls. The recognition of sadness expression positively correlated with the levels of anxiety and depression, while and the recognition of fear expression negatively correlated with depression in the stroke group. Conclusions: After an ischemic stroke, patients exhibit impairment in social cognition skills, specifically facial emotion recognition, in association with behavioral symptoms.

https://doi.org/10.1590/1980-57642021dn15-020010 274 downloads

Effects of Inspiratory Muscle Training Using an Electronic Device on Patients Undergoing Cardiac Surgery: A Randomized Controlled Trial
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Fortes, João Vyctor Silva

; Borges, Mayara Gabrielle Barbosa

; Marques, Maria Jhany da Silva

; Oliveira, Rafaella Lima

; Rocha, Liana Rodrigues da

; Castro, Érica Miranda de

; Esquivel, Mateus Souza

; Borges, Daniel Lago

International Journal of Cardiovascular Sciences

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feb 2021, Volume 34 N. 1 Pages 44 - 52

Abstract: En | Text: En | PDF: En

Abstract Background Cardiac surgery causes pathophysiological changes that favor the occurrence of pulmonary and functional complications. Objective To investigate the effects of inspiratory muscle training (IMT) with an electronic device on patients undergoing cardiac surgery. Methods A randomized controlled trial was conducted with 30 adult patients undergoing elective cardiac surgery. A control group (CG) received conventional physical therapy care, and an intervention group (IG) received IMT using the POWERbreathe K5® electronic device. Two daily sessions of physical therapy were performed at the intensive care unit and one daily session at the ward until the sixth postoperative day. The following variables were measured preoperatively and on the sixth postoperative day, in both groups: inspiratory muscle strength, dynamic inspiratory muscle strength, and peak inspiratory flow. Data distribution was evaluated by the Shapiro-Wilk test. Analysis of variance was used, and the results were considered statistically significant when p < 0.05. Results Maximal inspiratory pressure (71.7 ± 17.1 cmH2O vs 63.3 ± 21.3 cmH2O; p = 0.11], S-index (52.61 ± 18.61 vs 51.08 ± 20.71), and peak inspiratory flow [(2.94 ± 1.09 vs 2.79 ± 1.26)] were maintained in the IG but had a significant reduction in the CG. Conclusion IMT performed with an electronic device was effective at maintaining inspiratory muscle strength, dynamic inspiratory muscle strength, and peak inspiratory flow when compared to conventional physical therapy. Int J Cardiovasc Sci. 2020; [online].ahead print, PP.0-0

https://doi.org/10.36660/ijcs.20190093 413 downloads

Cutaneous leishmaniasis spatial distribution and epidemiological and environmental risk factors in Cametá, state of Pará, Brazil
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da Silva Sousa Júnior, Alcinês

; Gonçalves, Nelson Veiga

; do Socorro Carvalho Miranda, Cláudia

; de Oliveira Santos, Bruno

; de Oliveira, Rafael Aleixo Coelho

; da Costa, Rodrigo Junior Farias

; da Trindade Noguchi, Selma Kazumi

; de Sousa Oliveira, João Sérgio

; Matsumura, Erica Silva Souza

; da Cunha Menezes Palácios, Vera Regina

Brazilian Journal of Infectious Diseases

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aug 2020, Volume 24 N. 4 Pages 330 - 336

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.bjid.2020.06.008 418 downloads

Clinical and molecular correlates of the ASPECTS in the acute phase of stroke
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MOURÃO, Aline Mansueto

; VICENTE, Laélia Cristina Caseiro

; ABREU, Mery Natali Silva

; SANT’ANNA, Romeu Vale

; DE MEIRA, Fidel Castro Alves

; XAVIER, Rodrigo Menezes de Brito

; TANURE, Marco Túlio de Azevedo

; VIEIRA, Erica Leandro Marciano

; DE SOUZA, Leonardo Cruz

; MIRANDA, Aline Silva de

; RACHID, Milene Alvarenga

; TEIXEIRA, Antônio Lucio

Arquivos de Neuro-Psiquiatria

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may 2020, Volume 78 N. 5 Pages 262 - 268

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: A Alberta Stroke Early Score (ASPECTS) foi desenvolvida para monitorização de alterações isquêmicas precoces na tomografia computadorizada de crânio, estando associada a desfechos clínicos. A ASPECTS também pode se associar aos biomarcadores periféricos que refletem a resposta fisiopatológica do cérebro ao AVC isquêmico. Objetivo: Investigar à associação entre os parâmetros periféricos com a Alberta Stroke Early Score (ASPECTS) em indivíduos após acidente vascular cerebral isquêmico. Métodos: Pacientes acima de 18 anos com AVC isquêmico agudo foram incluídos neste estudo. Nenhum paciente foi elegível para trombólise. Os pacientes foram submetidos à tomografia computadorizada sem contraste nas primeiras 24 horas da admissão, a ASPECTS e as avaliações clínicas e moleculares aplicadas no mesmo dia. O National Institutes of Health Stroke Scale (NIHSS), a escala de Rankin modificada e o Mini Exame do Estado Mental para avaliação clínica também foram aplicados a todos os indivíduos. Os níveis plasmáticos de BDNF, VCAM-1, VEGF, IL-1β, sTNFRs e adiponectina foram determinados por ELISA. Resultados: Pior desempenho neurológico (NIHSS), cognitivo (MEEM) e funcional (Rankin) foram observados no grupo com alterações na ASPECTS. Pacientes com alterações na ASPECTS também exibiram níveis mais altos de IL-1β e adiponectina. Na regressão multivariada linear, foi encontrado um coeficiente R ajustado de 0,515, indicando adiponectina e NIHSS como preditores independentes para a ASPECTS. Conclusão: Os níveis plasmáticos de adiponectina estão associados aos escores da ASPECTS.

ABSTRACT Background: The Alberta Stroke Program Early CT Score (ASPECTS) scale was developed for monitoring early ischemic changes on CT, being associated with clinical outcomes. The ASPECTS can also associate with peripheral biomarkers that reflect the pathophysiological response of the brain to the ischemic stroke. Objective: To investigate the association between peripheral biomarkers with the Alberta Stroke Program Early CT Score (ASPECTS) in individuals after ischemic stroke. Methods: Patients over 18 years old with acute ischemic stroke were enrolled in this study. No patient was eligible for thrombolysis. The patients were submitted to non-contrast CT in the first 24 hours of admission, being the Alberta Stroke Program Early CT Score and clinical and molecular evaluations applied on the same day. The National Institutes of Health Stroke Scale (NIHSS), modified Rankin scale and the Mini-Mental State Examination for clinical evaluation were also applied to all subjects. Plasma levels of BDNF, VCAM-1, VEGF, IL-1β, sTNFRs and adiponectin were determined by ELISA. Results: Worse neurological impairment (NIHSS), cognitive (MEEM) and functional (Rankin) performance was observed in the group with changes in the NCTT. Patients with NCTT changes also exhibited higher levels of IL-1β and adiponectin. In the linear multivariate regression, an adjusted R coefficient of 0.515 was found, indicating adiponectin and NIHSS as independent predictors of ASPECTS. Conclusion: Plasma levels of adiponectin are associated with the ASPECTS scores.

https://doi.org/10.1590/0004-282x20200001 1343 downloads

10.

Elaboração e validação de uma tecnologia educacional acerca da violência contra a mulher
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Sousa, Elayne Kelly Sepedro

; Morais, Erica Jorgiana dos Santos de

; Amorim, Fernanda Cláudia Miranda

; Oliveira, Adélia Dalva da Silva

; Sousa, Kayo Henrique Jardel Feitosa

; Almeida, Camila Aparecida Pinheiro Landim

Escola Anna Nery

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2020, Volume 24 N. 4 elocation e20190314

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objective To develop and validate an educational technology about violence against women. Method A methodological study of content and appearance validation. For validation, 11 content specialists and technicians, 7 design specialists and 79 women participated in this study. Three instruments were used for data collection, one for each group of participants, and the data were analyzed for level of agreement and Content Validity Index. Results The average agreement of the content specialists and technicians was 87%, the global Content Validity Index by the design specialists was 0.92 and the level of agreement of the positive responses by the target audience was 96.2%. Conclusion and implications for practice The “Alertmeter” proved to be a valid educational technology to be used, as it promotes knowledge about the various manifestations of violence against women.

RESUMEN Objetivo desarrollar y validar tecnología educativa sobre la violencia contra la mujer. Método estudio metodológico del contenido y validación de la apariencia. Para la validación, 11 especialistas y técnicos de contenido, 7 especialistas en diseño y 79 mujeres participaron en este estudio. Se utilizaron tres instrumentos para la recopilación de datos, uno para cada grupo de participantes, y los datos se analizaron para determinar el nivel de acuerdo y el Índice de validez del contenido. Resultados el acuerdo promedio de los especialistas y técnicos de contenido fue del 87%, el índice de validez de contenido global por parte de los especialistas en diseño fue de 0.92 y el nivel de acuerdo de las respuestas positivas por parte del público objetivo fue de 96 2% Conclusión e implicaciones para la práctica el “Alertômetro” demostró ser una tecnología educativa válida para ser utilizada, ya que promueve el conocimiento sobre las diversas manifestaciones de violencia contra las mujeres.

RESUMO Objetivo elaborar e validar uma tecnologia educacional acerca da violência contra a mulher. Método estudo metodológico de validação de conteúdo e aparência. Para a validação, participaram deste estudo 11 especialistas de conteúdo e técnicos, 7 especialistas de design e 79 mulheres. Foram utilizados três instrumentos para a coleta de dados, um para cada grupo de participantes, e os dados foram analisados quanto ao nível de concordância e Índice de Validade de Conteúdo. Resultados a média de concordância dos especialistas de conteúdo e técnicos foi de 87%, o Índice de Validade de Conteúdo global por parte dos especialistas de design foi de 0,92 e o nível de concordância das respostas positivas pelo público-alvo foi de 96,2%. Conclusão e implicações para a prática o Alertômetro mostrou-se uma tecnologia educacional válida para ser utilizada, pois promove conhecimento acerca das diversas manifestações da violência contra a mulher.

https://doi.org/10.1590/2177-9465-ean-2019-0314 155 downloads

11.

Elaboração e validação de uma tecnologia educacional acerca da violência contra a mulher
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Sousa, Elayne Kelly Sepedro

; Morais, Erica Jorgiana dos Santos de

; Amorim, Fernanda Cláudia Miranda

; Oliveira, Adélia Dalva da Silva

; Sousa, Kayo Henrique Jardel Feitosa

; Almeida, Camila Aparecida Pinheiro Landim

Escola Anna Nery

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2020, Volume 24 N. 4 elocation e20190314

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/2177-9465-ean-2019-0314 1757 downloads

12.

Are public health researchers in Brazil ready and supported to do knowledge translation?
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Miranda, Érica da Silva

; Figueiró, Ana Cláudia

; Potvin, Louise

Cadernos de Saúde Pública

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2020, Volume 36 N. 4 elocation e00003120

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/0102-311x00003120

13.

Are public health researchers in Brazil ready and supported to do knowledge translation?
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Miranda, Érica da Silva

; Figueiró, Ana Cláudia

; Potvin, Louise

Cadernos de Saúde Pública

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2020, Volume 36 N. 4 elocation e00003120

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/0102-311x00003120 480 downloads

14.

Detection of Drug Resistant Mycobacterium Tuberculosis Strains Using Kit SIRE Nitratase®: a Multicenter Study
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Miranda, Silvana Spindola de

; Almeida, Isabela Neves de

; Mansur, Maria de Fátima Filardi Oliveira

; Figueredo, Lida Jouca de Assis

; Carvalho, Wânia da Silva

; Hadaad, João Paulo Amaral

; Diniz, Jaciara de Lourdes do Carmo Guimarães

; Groll, Andrea von

; Silva, Pedro Almeida da

; Lopes, Maria Luiza

; Santos, Marcelo Cordeiro dos

; Brito, Alexandra

; Mello, Fernanda Carvalho de Queiroz

; Malaquias, Thiago da Silva Santos

; Croda, Julio

; Pinhata, Juliana Maira Watanabe

; Oliveira, Rosângela Siqueira de

; Chimara, Erica

; Rossetti, Maria Lúcia

; Halon, Maria Laura

; Lourenço, Maria Cristina

; Medeiros, Reginalda Ferreira de Melo

; Montes, Fátima Cristina Onofre Fandinho

; Machado, Diana

; Viveiros, Miguel

; Kritski, Afrânio Lineu

Brazilian Archives of Biology and Technology

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2020, Volume 63 elocation e20190179

Abstract: En | Text: En | PDF: En

Abstract (1) Background: The Commercial Kit SIRE Nitratase® PlastLabor, is a drug susceptibility test kit used to detect Mycobacterium tuberculosis resistance to first-line TB treatment drugs. The present study aimed at evaluating its performance in a multicenter study. (2) Methods: To determine its accuracy, the proportion methods in Lowenstein Jensen medium or the BACTECTMMGITTM960 system was used as a gold standard. (3) Results: The study revealed that the respective accuracies of the kit with 190 M. tuberculosis clinical isolates, using the proportion methods in Lowenstein Jensen medium or BACTECTMMGITTM960 system as a gold standard, were 93.9% and 94.6%, 96.9% and 94.6%, 98.0% and 97.8%, and 98.0% and 98.9%, for streptomycin, isoniazid, rifampicin, and ethambutol, respectively. (4) Conclusion: Thus, the kit can rapidly screen resistance to streptomycin, isoniazid, rifampicin, and ethambutol. Additionally, it does not require sophisticated equipment; hence, it can be easily used in the laboratories of low and middle income countries.

https://doi.org/10.1590/1678-4324-2020190179 905 downloads

15.

Increased quality of in natura and cryopreserved semen of water buffaloes supplemented with saturated and unsaturated fatty acids from the palm oil industry
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Silva, Lílian Kátia Ximenes

; Lourenço Júnior, José de Brito

; Silva, Aluizio Otavio Almeida da

; Sousa, José Silva de

; Silva, André Guimarães Maciel e

; Reis, Adriana Novaes dos

; Miranda, Moysés dos Santos

; Santos, Simone do Socorro Damasceno

; Ohashi, Otávio Mitio

; Martorano, Lucieta Guerreiro

; Rocha Filho, Geraldo Narciso da

; Faturi, Cristian

; Morais, Eziquiel de

; Mares, Érica Karine Lourenço

; Garcia, Alexandre Rossetto

Animal Reproduction

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2020, Volume 17 N. 4 elocation e20200522

Abstract: En | Text: En | PDF: En

Abstract Ruminant energy supplementation with vegetable oils or fats has been standing out worldwide and oil palm processing has been receiving growing interest. This study assessed the effect of supplementation with saturated and unsaturated fatty acids from the palm oil industry on the lipid profile of seminal plasma and of the sperm membrane, as well as on the morphological and functional characteristics of raw and cryopreserved buffalo semen. Twelve purebred Murrah bulls (Bubalus bubalis) were assigned to the experimental groups and fed diets for 120 days with no added lipids (CONT, four bulls), or with an extra amount of 3% lipids from crude palm oil (PALM, four bulls), or from palm oil deodorizer distillate (PODD, four bulls). Semen was collected and cryopreserved every 15 days. The lipid composition of membranes and semen quality were determined after collections. Lipid supplementation did not impact feed intake (P>0.05). Diet enrichment with PALM increased the linoleic acid (C18:2,ω6) in seminal plasma. Lipid supplementation did not increase the polyunsaturated fatty acids in the sperm membrane composition, but significantly increased the lignoceric acid (C24:0). Cryopreserved semen of the supplemented bulls presented higher progressive motility (60.2 vs. 67.9 vs. 65.2%; P<0.05) and sperm viability detected by eosin-nigrosin staining (61.1 vs. 69.4 vs. 67.8%; P<0.05). Palm oil reduced major sperm defects in both raw (12.2 vs. 9.3 vs. 13.2%; P<0.0001) and cryopreserved semen (12.4 vs. 9.4 vs. 11.2%; P<0.0001). The lipids added to the diet did not impact the population of spermatozoa with intact plasma and acrosomal membranes (PI-/PSA-), but significantly increased the percentage of spermatozoa with high mitochondrial potential (25.6 vs. 31.5 vs. 32.0%; P=0.008). The results suggest that lipid supplementation based on crude palm oil or palm oil deodorizer distillate can be safely used to feed buffalo bulls and may increase sperm attributes related to male fertility.

https://doi.org/10.1590/1984-3143-ar2020-0522 746 downloads

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