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Resumo O desenvolvimento humano é influenciado pela interação entre fatores biológicos e sociais. Este estudo teve como objetivo verificar o efeito moderador do risco social na relação entre risco biológico e desenvolvimento infantil. Os dados foram coletados em 201 crianças, com idades entre 6 e 72 meses. A variável independente foi medida pelo índice de risco biológico, e a variável moderadora pelo índice de risco social. O desenvolvimento infantil foi avaliado por meio do teste Denver II. Regressão linear, tamanho do efeito e análise de moderação foram utilizados para verificar a relação entre IRB e o desenvolvimento infantil (Denver II) e o efeito moderador do IRS. O IRB associou-se negativamente ao desenvolvimento infantil, a interação entre o IRB e o IRS aumentou a variância explicada no resultado do Denver II para 14%. O IRS também foi um moderador significativo dos domínios Linguagem e Motor Grosso. Esta pesquisa evidenciou que o risco social é um moderador da relação entre risco biológico e desenvolvimento infantil; quanto mais fatores de risco social, mais forte essa relação se torna. Por outro lado, pode-se dizer que alguns fatores sociais favorecem o desenvolvimento infantil, mesmo na presença de fatores de risco biológicos. 20 crianças 7 meses linear associouse associou 14 14% Grosso torna lado podese pode 2 1

Abstract Human development is influenced by the interaction between biological and social factors. This study aimed to verify the moderating effect of social risk on the relationship between biological risk and child development. Data were collected on 201 children, aged 6 to 72 months. The independent variable was measured by the biological risk index, and the moderator variable by the social risk index was assessed by the Denver II test. Linear regression, effect size, and analysis of moderation were used to verify the relationship between BRI and the child development (Denver II), and the moderating effect of the SRI. BRI was negatively associated with child development, the interaction between the BRI and SRI increased the explained variance in the Denver II result to 14%. The SRI was also a significant moderator of the Language and Gross Motor domains. This research evidence that social risk moderates the relationship between biological risk and child development, the more social risk factors, the stronger this relationship becomes. On the other hand, it can be said that some social factors favor child development, even in the presence of biological risk factors. 20 children 7 months test regression size II, , II) 14 14% domains becomes hand 2 1

https://doi.org/10.1590/1413-81232024298.18432022

Psychometric properties and reliability of the Brazilian version of Parent Attitudes about Childhood Vaccine (PACV-BR) PACVBR PACV BR (PACV-BR
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Santos Júnior, Claudio José dos

; Silva, Maria Rosa da

; Costa, Paulo José Medeiros de Souza

Revista Paulista de Pediatria

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2024, Volume 42 elocation e2023019

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Avaliar as propriedades psicométricas e a confiabilidade da versão brasileira do instrumento Parent Attitudes about Childhood Vaccine (PACV-BR). Métodos: A amostra incluiu 110 pais de crianças de até dois anos atendidas em Unidades Básicas de Saúde da Família. A consistência interna e a validade fatorial do instrumento foram avaliadas, respectivamente, pelo alfa de Cronbach e pela análise fatorial exploratória (EFA). A confiabilidade teste-reteste foi avaliada pelo coeficiente de correlação intraclasse (ICC). Resultados: Os resultados da AFE indicaram adequação estrutural do PACV-BR (15 itens e dois fatores). A confiabilidade indicou valores de alfa de Cronbach entre 0,715 e 0,854 para os itens, de 0,918 para o instrumento como um todo, de 0,877 para o fator 1 e de 0,825 para o fator 2, além de ICC de 0,984. Conclusões: O PACV-BR apresentou evidências de validade de construto e confiabilidade. Objetivo PACVBR. PACVBR PACV BR . (PACV-BR) Métodos 11 Família avaliadas respectivamente EFA. EFA (EFA) testereteste teste reteste ICC. (ICC) Resultados 15 (1 fatores. fatores fatores) 0715 0 715 0,71 0854 854 0,85 0918 918 0,91 todo 0877 877 0,87 0825 825 0,82 2 0984 984 0,984 Conclusões (PACV-BR (EFA (ICC ( 071 71 0,7 085 85 0,8 091 91 0,9 087 87 082 82 098 98 0,98 07 7 0, 08 8 09 9

ABSTRACT Objective: To evaluate the psychometric properties and reliability of the Brazilian version of the tool Parent Attitudes about Childhood Vaccine (PACV-BR). Methods: The sample included 110 parents of children up to two years old served by Family Health Basic Units. The tool's internal consistency and factor validity were respectively assessed by Cronbach's alpha and exploratory factor analysis (EFA). The test-retest reliability was assessed by the intraclass correlation coefficient (ICC). Results: The EFA results indicated a proper structural adequacy of the PACV-BR (15 items and two factors). The reliability generated Cronbach's alpha values between 0.715 and 0.854 for the items, of 0.918 for the tool as a whole, of 0.877 for factor 1 and of 0.825 for factor 2, in addition to an ICC of 0.984. Conclusions: The PACV-BR showed evidence of construct validity and reliability. Objective PACVBR. PACVBR PACV BR . (PACV-BR) Methods 11 Units tools s Cronbachs Cronbach EFA. (EFA) testretest test retest ICC. (ICC) Results 15 (1 factors. factors factors) 0715 0 715 0.71 0854 854 0.85 0918 918 0.91 whole 0877 877 0.87 0825 825 0.82 2 0984 984 0.984 Conclusions (PACV-BR (EFA (ICC ( 071 71 0.7 085 85 0.8 091 91 0.9 087 87 082 82 098 98 0.98 07 7 0. 08 8 09 9

https://doi.org/10.1590/1984-0462/2024/42/2023019

In vitro susceptibility to fosfomycin in clinical and environmental extended-spectrum beta-lactamase producing and/or ciprofloxacin-non-susceptible Escherichia coli isolates extendedspectrum extended spectrum betalactamase beta lactamase andor or ciprofloxacinnonsusceptible ciprofloxacin non susceptible
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Ribeiro, Victoria Stadler Tasca

; Bail, Larissa

; Ito, Carmen Antonia Sanches

; Andrade, Ana Paula de

; Arend, Lavinia Nery Villa Stangler

; Suss, Paula Hansen

; Nogueira, Keite da Silva

; Walflor, Haniel Siqueira Mortagua

; Faoro, Helisson

; Kuczera, Lia Carolina Soares de Medeiros

; Vicenzi, Fernando José

; Tuon, Felipe Francisco

Revista do Instituto de Medicina Tropical de São Paulo

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2024, Volume 66 elocation e5

Abstract: En | Text: En | PDF: En

ABSTRACT Extended-spectrum beta-lactamase producing and ciprofloxacin-non-susceptible Escherichia coli are clinical and environmental issues. We evaluated the susceptibility profile of fosfomycin in non-susceptible E. coli isolated from urine and the environment. We measured the activity of fosfomycin against 319 and 36 E. coli strains from urine and environmental isolates, respectively, collected from rivers. Fosfomycin resistance profiles were investigated using the minimal inhibitory concentration (MIC), according to the Clinical and Laboratory Standards Institute (CLSI) and the European Committee for Antimicrobial Susceptibility Testing (EUCAST) guidelines. Antibiotic susceptibility testing revealed that 5% and 6.6% of urine samples were non-susceptible to fosfomycin according to CLSI and EUCAST guidelines, respectively. The fosfomycin MIC50/90 was 0.5/4 mg/L. Of the 36 E. coli isolates from river water, 11.1% and 13,8% were non-susceptible to fosfomycin according to CLSI and EUCAST, respectively (range ≤0.25 ≥512 mg/L). All the isolates with MIC ≥512 mg/L for fosfomycin showed the fosA3 gene. Fosfomycin resistance was more frequent in the environment than in clinical samples. Extendedspectrum Extended spectrum betalactamase beta lactamase ciprofloxacinnonsusceptible ciprofloxacin non susceptible issues nonsusceptible E 31 3 rivers MIC, , (MIC) (CLSI (EUCAST guidelines 5 66 6 6.6 MIC5090 MIC50 90 MIC50/9 054 0 4 0.5/ mgL mg L water 111 11 1 11.1 138 13 8 13,8 range 025 25 ≤0.2 512 ≥51 . mg/L) fosA gene (MIC 6. MIC509 MIC5 9 MIC50/ 05 0.5 11. 13, 02 2 ≤0. 51 ≥5 0. ≤0 ≥ ≤

https://doi.org/10.1590/s1678-9946202466005

Moderating effect of social risk on the relationship between biological risk and child development
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Santos, Janaina Araujo Teixeira

; Ayupe, Kênnea Martins Almeida

; Camargos, Ana Cristina Resende

; Medeiros, Naguia Leticia

; Gutierres Filho, Paulo José Barbosa

Ciência & Saúde Coletiva

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2024, Volume 29 N. 8 elocation e18432022

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232024298.18432022

Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study factors incidence capital crosssectional cross sectional
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Pires, Cássia de Paula

; Mareto, Lisany Krug

; Medeiros, Márcio José de

; Oliveira, Everton Falcão de

Revista do Instituto de Medicina Tropical de São Paulo

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2024, Volume 66 elocation e21

Abstract: En | Text: En | PDF: En

ABSTRACT Maternal and child health remains an enduring global challenge, having occupied a prominent position on international agendas since the dawn of the 21st century. During pregnancy, syphilis emerges as the second most prevalent cause of stillbirth on a global scale, potentially leading to a range of adverse outcomes. This study aimed to describe the clinical and epidemiological profile of cases of gestational and congenital syphilis and the hospital care provided for newborns in Campo Grande municipality, Mato Grosso do Sul State, Brazil, from 2013 to 2018. This is a cross-sectional study based on data from Brazilian Notifiable Diseases Surveillance System (SINAN) and hospital medical records. Chi-square or Fisher’s exact test and logistic regression analysis were used to assess the associations and relationships between the child’s clinical outcome at birth and the mother’s clinical-obstetric and epidemiological characteristics. Cumulative detection rate of gestational syphilis was 174.3 cases per 1,000 live births and cumulative incidence of congenital syphilis was 47.7 cases per 1,000 live births. Alcoholism, prenatal care, number of prenatal visits, maternal treatment regimen, and timing of maternal diagnosis were associated with child’s clinical outcome at birth and considered in the regression model. Prenatal visits showed a protective effect against the signs and symptoms of congenital syphilis (odds ratio = 0.37; 95% confidence interval = 0.17−0.77). Medical assistance was considered inadequate in 62.3% of cases. Prenatal consultations should be encouraged among pregnant women. There is a need for better education of health personnel on the treatment and diagnosis of syphilis. challenge st century pregnancy scale outcomes municipality State Brazil 201 2018 crosssectional cross sectional SINAN (SINAN records Chisquare Chi square Fishers Fisher s childs mothers mother clinicalobstetric obstetric characteristics 1743 174 3 174. 1000 1 000 1,00 477 47 7 47. Alcoholism regimen model odds 0.37 037 0 37 95 0.17−0.77. 017077 0.17−0.77 . 17 77 0.17−0.77) 623 62 62.3 women 20 100 00 1,0 4 0.3 03 9 01707 0.17−0.7 6 62. 2 10 1, 0. 0170 0.17−0. 017 0.17−0 01 0.17− 0.17 0.1

https://doi.org/10.1590/s1678-9946202466021

CodiReal-PT: National Survey on Current Practices in Right Colon Oncological Surgery CodiRealPT CodiReal PT CodiReal-PT
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Azevedo, José Gonçalves Moreira de

; Sousa, Maria João Morais do Carmo Couto de

; Cunha, Miguel Fernandes da Conceição

; Fernandez, Laura Melina

; Rama, Nuno José Gomes

; Quintanilha, Rui Paulo de Medeiros

Journal of Coloproctology (Rio de Janeiro)

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2024, Volume 44 N. 3 Pages 171 - 179

Abstract: En | Text: En | PDF: En

Abstract Introduction Colorectal cancer (CRC) is the third most prevalent tumor. Right colon cancer (RCC) comprises one-third of CRC cases and is associated with poorer outcomes, emphasizing the need for optimized treatment strategies. The present study aims to explore the nuances in the management of RCC across Portugal, focusing on surgical approaches and multidisciplinary treatment. Materials and Methods The CodiReal-PT was a cross-sectional survey-based study adhering to the guidelines of the Checklist for Reporting Results of Internet E-Surveys (CHERRIES), focusing on current practices in RCC oncological surgery. The survey comprised 31 questions divided into 4 sections (demographics, multidisciplinary approach, surgery practices regarding RCC, and postoperative management). It was made available via e-mail to all active members of the Portuguese Society of Surgery (Sociedade Portuguesa de Cirurgia, SPCIR, in Portuguese), and data collection lasted from November to December 2022. Results Data from 69% of Portuguese public hospitals was obtained. All the participant hospitals had multidisciplinary team meetings to manage CRC cases. However, 17% (n = 6) did not discuss all elective-setting cases during their meetings. Dedicated colorectal surgical teams were present in 86% (n = 31) of hospitals. Furthermore, the presence of these dedicated teams was associated with better practices, namely a higher volume of right colectomies (mean: 51.8 ± 32.6 versus 23.8 ± 4.8; p = 0.001), a preference for the laparoscopic approach (93.5 versus 60.0%; p = 0.021), and standardization of anastomotic techniques (83.9 versus 40.0%; p = 0.029). Conclusion The present nationwide survey-based study provides a comprehensive landscape of RCC management practices across Portugal, underscoring the significant role of dedicated colorectal surgical teams and the need for further practice standardization. Nevertheless, multidisciplinary team meetings in all surveyed hospitals are an important indicator of improved RCC care. Future research should focus on the impact of specific surgical techniques on oncological outcomes and the potential benefits of centralizing care to high-volume centers. (CRC tumor (RCC onethird one strategies Portugal CodiRealPT CodiReal PT crosssectional cross sectional surveybased based ESurveys E Surveys CHERRIES, CHERRIES , (CHERRIES) 3 demographics, demographics (demographics management. . management) email e mail Sociedade Cirurgia SPCIR Portuguese, Portuguese) 2022 69 obtained However 17 n 6 electivesetting elective setting 86 Furthermore mean (mean 518 51 8 51. 326 32 32. 238 23 23. 4.8 48 0.001, 0001 0.001 0 001 0.001) 93.5 935 93 5 (93. 60.0% 600 60 0.021, 0021 0.021 021 0.021) 83.9 839 83 9 (83. 40.0% 400 40 0.029. 0029 0.029 029 0.029) Nevertheless highvolume high centers (CHERRIES 202 1 2 4. 000 0.00 00 93. (93 60.0 002 0.02 02 83. (83 40.0 20 0.0 (9 60. (8 40. 0. (

https://doi.org/10.1055/s-0044-1788912

Criação e validação de face e conteúdo de simulador realístico para treinamento de cistostomia suprapúbica
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Anselmo, Christophe Bezerra

; Souza Neto, José Luiz de

; Santos Junior, José Ademar dos

; Silva, Rodolfo Alves da

; Medeiros, Paulo José de

Revista Brasileira de Educação Médica

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2024, Volume 48 N. 4 elocation e095

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: A realização da cistostomia suprapúbica deve ser uma competência do médico urologista e cirurgião geral. O treinamento dessa competência por meio da simulação surge como alternativa segura, livre de riscos para pacientes e médicos residentes. Objetivo: Este estudo teve como objetivos criar um simulador realístico para o treinamento de cistostomia suprapúbica e obter sua validação de face e conteúdo. Método: O procedimento foi realizado no simulador por especialistas que posteriormente responderam a um questionário semiestruturado para a avaliação do realismo anatômico e a utilidade do simulador como ferramenta de ensino e treinamento. Resultado: Avaliaram o simulador 21 urologistas com idade média de 41,2 anos. O realismo anatômico teve nota média de 4,24 (nota máxima: 5), e a utilidade como ferramenta de ensino obteve média de 4,76 (nota máxima: 5). Conclusão: O simulador desenvolvido é, portanto, útil para o ensino prático de cistostomia por punção, pois foi validado em face e conteúdo, e, por isso, pode ser incorporado aos currículos da formação de médicos residentes, sobretudo em cirurgia geral e urologia. Introdução segura residentes Objetivo conteúdo Método Resultado 2 412 41 41, anos 424 4 24 4,2 máxima 5, 5 , 5) 476 76 4,7 5. . Conclusão é portanto punção isso urologia 42 4, 47 7

ABSTRACT Introduction: Performing a suprapubic cystostomy should be a competence of the urologist and general surgeon. The training of this competence through simulation appears as a safe, risk-free alternative for patients and resident physicians. Objective: to create a realistic simulator for suprapubic cystostomy training and obtain its face and content validation. Method: the procedure was carried out in the simulator by experts who later responded to a semi-structured questionnaire to evaluate anatomical realism and the usefulness of the simulator as a teaching and training tool. Results: Twenty-one urologists with a mean age of 41.2 years evaluated the simulator. Anatomical realism had an average score of 4.24 (maximum score 5) and usefulness as a teaching tool obtained an average of 4.76 (maximum score 5). Conclusion: the developed simulator is, therefore, useful for the practical teaching of puncture cystostomy, it was validated in terms of face and content, and can be incorporated into the curricula for the training of resident physicians, especially in general surgery and urology. Introduction surgeon safe riskfree risk free physicians Objective validation Method semistructured semi structured Results Twentyone Twenty one 412 41 2 41. 424 4 24 4.2 maximum 5 476 76 4.7 5. . Conclusion is therefore urology 42 4. 47 7

https://doi.org/10.1590/1981-5271v48.4-2022-0270

Diretriz de Tomografia Computadorizada e Ressonância Magnética Cardiovascular da Sociedade Brasileira de Cardiologia e do Colégio Brasileiro de Radiologia – 2024 202 20 2
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Magalhães, Tiago Augusto

; Carneiro, Adriano Camargo de Castro

; Moreira, Valéria de Melo

; Trad, Henrique Simão

; Lopes, Marly Maria Uellendahl

; Cerci, Rodrigo Julio

; Nacif, Marcelo Souto

; Schvartzman, Paulo R.

; Chagas, Antônio Carlos Palandrini

; Costa, Isabela Bispo Santos da Silva

; Schmidt, André

; Shiozaki, Afonso Akio

; Montenegro, Sérgio Tavares

; Piegas, Leopoldo Soares

; Zapparoli, Marcelo

; Nicolau, José Carlos

; Fernandes, Fabio

; Hadlich, Marcelo Souza

; Ghorayeb, Nabil

; Mesquita, Evandro Tinoco

; Gonçalves, Luiz Flávio Galvão

; Ramires, Felix José Alvarez

; Fernandes, Juliano de Lara

; Schwartzmann, Pedro Vellosa

; Rassi, Salvador

; Torreão, Jorge Andion

; Mateos, José Carlos Pachón

; Beck-da-Silva, Luiz

; Silva, Marly Conceição

; Liberato, Gabriela

; Oliveira, Gláucia Maria Moraes de

; Feitosa Filho, Gilson Soares

; Carvalho, Hilka dos Santos Moraes de

; Markman Filho, Brivaldo

; Rocha, Ricardo Paulo de Sousa

; Azevedo Filho, Clerio Francisco de

; Taratsoutchi, Flávio

; Coelho-Filho, Otavio Rizzi

; Kalil Filho, Roberto

; Hajjar, Ludhmila Abrahão

; Ishikawa, Walther Yoshiharu

; Melo, Cíntia Acosta

; Jatene, Ieda Biscegli

; Albuquerque, Andrei Skromov de

; Rimkus, Carolina de Medeiros

; Silva, Paulo Savoia Dias da

; Vieira, Thiago Dieb Ristum

; Jatene, Fabio Biscegli

; Azevedo, Guilherme Sant Anna Antunes de

; Santos, Raul D.

; Monte, Guilherme Urpia

; Ramires, José Antonio Franchini

; Bittencourt, Marcio Sommer

; Avezum, Alvaro

; Silva, Leonardo Sara da

; Abizaid, Alexandre

; Gottlieb, Ilan

; Precoma, Dalton Bertolim

; Szarf, Gilberto

; Sousa, Antônio Carlos Sobral

; Pinto, Ibraim Masciarelli Francisco

; Medeiros, Fábio de Morais

; Caramelli, Bruno

; Parga Filho, José Rodrigues

; Santos, Tiago Senra Garcia dos

; Prazeres, Carlos Eduardo Elias dos

; Lopes, Marcelo Antonio Cartaxo Queiroga

; Avila, Luiz Francisco Rodrigues de

; Scanavacca, Mauricio Ibrahim

; Gowdak, Luis Henrique Wolff

; Barberato, Silvio Henrique

; Nomura, Cesar Higa

; Rochitte, Carlos Eduardo

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 9 elocation e20240608

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.36660/abc.20240608

Physical rehabilitation in Brazilian pediatric intensive care units: a multicenter point prevalence study units
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Redivo, Juliana

; Kannan, Harini

; Souza, Andreia Aparecida Freitas

; Colleti Junior, José

; Kudchadkar, Sapna Ravi

; Horigoshi, Nelson Kazunobu

; Costa, Graziela de Araújo

; Castilho, Taísa Roberta Ramos de

; Peron, Paula Peres Domingues

; Scaranto, Walter Perez

; Medeiros, Daniela Nasu Monteiro

; Matsumoto, Toshio

; Almeida, Carlos Gustavo de

; Oliveira, Felipe Rezende Caino de

; Brandão, Marcelo Barciela

; Lima-Setta, Fernanda

; Prata-Barbosa, Arnaldo

; Xavier, Glaciele Nascimento

; Andrade, Livia Barbosa de

; Aguiar, Agda Ultra de

; Coutinho, Marcos Paulo Galdino

; Castro, Roberta Esteves Viera de

; Landy, Glazia André

; Balaniuc, Suzana Lopes Bonfim

; Yamaguchi, Ricardo Silveira

Critical Care Science

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sep 2023, Volume 35 N. 3 Pages 290 - 301

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Determinar a prevalência e os fatores associados à reabilitação física de crianças em estado grave em unidades de terapia intensiva pediátrica brasileiras. Métodos: Realizou-se um estudo de prevalência pontual multicêntrico, transversal, de 2 dias, abrangendo 27 unidades de terapia intensiva pediátrica (do total de 738) no Brasil em abril e junho de 2019. Este estudo brasileiro fez parte de um grande estudo multinacional chamado Prevalence of Acute Rehabilitation for Kids in the PICU (PARK-PICU). O desfecho primário foi a prevalência de mobilidade proporcionada pela fisioterapia ou pela terapia ocupacional. Foram coletados prospectivamente dados clínicos sobre a mobilidade do paciente, possíveis eventos de segurança de mobilidade e barreiras de mobilização em pacientes admitidos por ≥ 72 horas. Resultados: As crianças com idade inferior a 3 anos eram 68% da população de pacientes. A prevalência de mobilidade fornecida pelo terapeuta foi de 74%, ou 277 dos 375 pacientes-dia. A mobilidade para fora do leito foi mais positivamente associada à presença de familiares (razão de chance ajustada de 3,31; IC95% 1,70 - 6,43) e mais negativamente associada às linhas arteriais (razão de chance ajustada de 0,16; IC95% 0,05 - 0,57). Foram relatadas barreiras à mobilização em 27% dos pacientes-dia, sendo a mais comum a falta de prescrição médica (n = 18). Registaram-se eventuais eventos de segurança em 3% de todos os eventos de mobilização. Conclusão: A mobilidade proporcionada pelo terapeuta nas unidades de terapia intensiva pediátrica brasileiras é frequente. A presença de familiares foi alta e positivamente associada à mobilidade para fora do leito. A presença de fisioterapeutas 24 horas por dia nas unidades de terapia intensiva pediátrica brasileiras pode exercer papel importante na mobilização de crianças em estado grave. Objetivo Métodos Realizouse Realizou se multicêntrico transversal dias 738 2019 PARKPICU. PARKPICU PARK . (PARK-PICU) ocupacional paciente 7 Resultados 68 74 74% 37 pacientesdia. pacientesdia dia. pacientes-dia razão 3,31 331 31 IC95 IC 170 1 70 1,7 6,43 643 6 43 0,16 016 0 16 005 05 0,0 0,57. 057 0,57 57 0,57) pacientesdia, dia, n 18. 18 18) Registaramse Registaram Conclusão frequente 73 201 (PARK-PICU 3,3 33 IC9 17 1, 6,4 64 4 0,1 01 00 0, 0,5 5 20 3, 6,

ABSTRACT Objective: To determine the prevalence and factors associated with the physical rehabilitation of critically ill children in Brazilian pediatric intensive care units. Methods: A 2-day, cross-sectional, multicenter point prevalence study comprising 27 pediatric intensive care units (out of 738) was conducted in Brazil in April and June 2019. This Brazilian study was part of a large multinational study called Prevalence of Acute Rehabilitation for Kids in the PICU (PARK-PICU). The primary outcome was the prevalence of mobility provided by physical therapy or occupational therapy. Clinical data on patient mobility, potential mobility safety events, and mobilization barriers were prospectively collected in patients admitted for ≥ 72 hours. Results: Children under the age of 3 years comprised 68% of the patient population. The prevalence of therapist-provided mobility was 74%, or 277 out of the 375 patient-days. Out-of-bed mobility was most positively associated with family presence (adjusted odds ratios 3.31;95%CI 1.70 - 6.43) and most negatively associated with arterial lines (adjusted odds ratios 0.16; 95%CI 0.05 - 0.57). Barriers to mobilization were reported on 27% of patient-days, the most common being lack of physician order (n = 18). Potential safety events occurred in 3% of all mobilization events. Conclusion: Therapist-provided mobility in Brazilian pediatric intensive care units is frequent. Family presence was high and positively associated with out-of-bed mobility. The presence of physiotherapists 24 hours a day in Brazilian pediatric intensive care units may have a substantial impact on the mobilization of critically ill children. Objective Methods 2day, 2day 2 day, 2-day crosssectional, crosssectional cross sectional, sectional cross-sectional 738 2019 PARKPICU. PARKPICU PARK . (PARK-PICU) 7 Results 68 population therapistprovided therapist 74 74% 37 patientdays. patientdays days. days patient-days Outofbed Out bed adjusted 3.3195%CI 33195CI CI 3.31 31 95 170 1 70 1.7 6.43 643 6 43 0.16 016 0 16 95CI 005 05 0.0 0.57. 057 0.57 57 0.57) patientdays, days, n 18. 18 18) Conclusion Therapistprovided Therapist frequent outofbed 73 201 (PARK-PICU 3195 331 3.3 9 17 1. 6.4 64 4 0.1 01 00 0. 0.5 5 20 319 33 3. 6.

https://doi.org/10.5935/2965-2774.20230388-en

10.

Vitamin D status and biomarkers of renal graft function after kidney transplantation: a longitudinal study
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Ferreira-deLima, Mabelle Alves

; Costa-de Souza, Karla Simone

; Endrigo-Silva-de Andrade, César

; Abbott-Galvão-Ururahy, Marcela

; de Medeiros, Paulo José

; Galvão-Pereira, Maurício

; de Almeida, José Bruno

; Cavalcanti-Maurício-Sena-Evangelista, Karine

; Augusto-de Rezende, Adriana

Nutrición Hospitalaria

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apr 2023, Volume 40 N. 2 Pages 412 - 418

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Introduction: low 25-hydroxyvitamin D [25(OH)D] levels occur after kidney transplantation (KTx), and can be associated with increase the risk of graft loss. This longitudinal study aimed to evaluate the vitamin D status and association with biomarkers of the renal graft function after KTx. Methods: this longitudinal study included 42 patients evaluated at baseline, 3 and 6 months after KTx. Biodemographic, clinical, and biochemical parameters such as 25(OH)D and parathyroid hormone (PTH), and biomarkers of renal graft function, such as creatinine, estimated glomerular filtration rate (eGFR), and urinary albumin/creatinine ratio (ACR), were assessed. Sun exposure was also evaluated. Patients were categorized according to their 25(OH)D levels. Results: at baseline, 25(OH)D levels < 30 ng/mL were found in 43 % patients, and 38 % of these patients failed to improve their 25(OH)D levels by 6 months after KTx. Low 25(OH)D levels occurred regardless of sun exposure. Further, 44 % patients developed albuminuria at 6 months. An increased ACR was observed in patients with 25(OH)D levels < 30 ng/mL (p = 0.002) compared to that in patients with 25(OH)D > 30 ng/mL. Additionally, 25(OH)D levels were negatively correlated with ACR at 6 months post-KTx (r = -0.444; p = 0.003). Twelve (28.6 %) patients with 25(OH)D levels < 30 ng/mL showed no eGFR recovery until 6 months after KTx. Conclusion: low vitamin D levels and increased albuminuria were observed at 6 months after KTx, even in a region with high sun exposure. The association between vitamin D status and biomarkers of renal graft function after KTx should be explored in further studies.

Resumen Introducción: los bajos niveles de 25-hidroxivitamina D [25(OH)D] ocurren después del procedimiento de trasplante de riñón (KTx) y pueden estar asociados con un aumento del riesgo de pérdida del injerto. Este estudio longitudinal tuvo como objetivo evaluar el estado de la vitamina D y la asociación con los biomarcadores de función del injerto renal después del KTx. Métodos: este estudio longitudinal incluyó a 42 pacientes que fueron evaluados al inicio del estudio, y 3 y 6 meses después del KTx. Se evaluaron los parámetros biodemográficos, clínicos y bioquímicos, como 25(OH)D y hormona paratiroidea (PTH), y los biomarcadores de función del injerto renal, como creatinina, tasa de filtración glomerular estimada (eGFR) y relación albúmina/creatinina (ACR). También se evaluó la exposición al sol. Los pacientes se clasificaron según sus niveles de 25(OH)D. Resultados: al inicio del estudio se encontraron niveles de 25(OH)D < 30 ng/ml en el 43 % de los pacientes, mientras que el 38 % de estos pacientes no lograron mejorar sus niveles de 25(OH)D a los 6 meses después del KTx. También se produjeron niveles bajos de 25(OH)D independientemente de la exposición al sol. Asimismo, el 44 % de los pacientes desarrollaron albuminuria a los 6 meses. Se observó un aumento de la ACR en los pacientes con niveles de 25(OH)D < 30 ng/mL (p = 0,002) en comparación con los pacientes con 25(OH)D > 30 ng/mL. Además, los niveles de 25(OH)D se correlacionaron negativamente con la ACR a los 6 meses después del KTx (r = -0,444; p = 0,003). Doce (28,6 %) pacientes con niveles de 25(OH)D < 30 ng/ml no mostraron recuperación de la TFGe hasta 6 meses después del KTx. Conclusión: se observaron niveles bajos de vitamina D y un aumento de la albuminuria a los 6 meses después del KTx, incluso en una región con alta exposición solar. La asociación entre el estado de la vitamina D y los biomarcadores de función del injerto renal después del KTx debe explorarse en estudios adicionales.

https://doi.org/10.20960/nh.04024

11.

Effectiveness of Agave genotype extracts applied alone or mixed with mineral oil against the cactus scale mealybug Diaspis echinocacti (Hemiptera: Diaspididae) Hemiptera (Hemiptera Diaspididae
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Albuquerque Junior, Paulo de Souza

; Silva, Carlos Alberto Domingues da

; Medeiros, Everaldo Paulo de

; Zanuncio, José Cola

Bragantia

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2023, Volume 82 elocation e20230024

Abstract: En | Text: En | PDF: En

ABSTRACT Synthetic insecticides used in the management of the mealybug Diaspis echinocacti (Bouché, 1833) (Hemiptera: Diaspididae) can contaminate co-products from this plant. The use of Agave extracts and/or mineral oil is a sustainable alternative to reduce the residual effect of these chemicals in the palm production chain. The objective here was to determine the effectiveness of Agave genotype extracts applied alone or mixed with mineral oil against the cactus scale mealybug D. echinocacti. Two experiments were carried out to achieve this goal. The first one aimed to select the most promising Agave genotype extract concentration (CL80) to kill 80% of the first instar mobile nymphs of D. echinocacti (Experiment 1), and the second to determine the effectiveness of the selected extract against nymphs, pupae, and adults of different ages of this mealybug in laboratory and greenhouse (Experiment 2). The extract of the genotype Agave fourcroydes cv. Cabinho with lethal concentration (LC80) of 10.9 mL/10 mL is the most efficient in causing mortality of D. echinocacti. The lethal concentration of the A. fourcroydes cv. Cabinho killed 80% of the first instar motile nymphs and more than 74% of the nymphs, pupae, and adults of different ages of D. echinocacti in the laboratory and greenhouse followed by Agave sisalana cv. Tatuí 3. Furthermore, the mortality of this scale mealybug was higher with applications of mineral oil (Assist), alone or mixed with sisal extracts. Bouché, Bouché (Bouché 1833 Hemiptera (Hemiptera Diaspididae coproducts co products plant andor chain D goal CL80 CL (CL80 80 Experiment 1, 1 , 1) pupae 2. 2 . 2) cv LC80 LC (LC80 109 10 9 10. mL10 mL/1 A 74 3 Furthermore Assist, Assist (Assist) 183 CL8 (CL8 8 LC8 (LC8 mL1 mL/ 7 (Assist 18 (CL (LC

https://doi.org/10.1590/1678-4499.20230024

12.

Atenção nutricional na Atenção Primária à Saúde: um estudo comparativo de duas macrorregiões do estado de São Paulo, Brasil Saúde Paulo
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Neves, José Anael

; Borysow, Igor da Costa

; Furtado, Juarez Pereira

; Medeiros, Maria Angélica Tavares de

Cadernos Saúde Coletiva

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2023, Volume 31 N. 2 elocation e31020411

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução Ainda que a importância das ações relacionadas à alimentação e à nutrição sejam reconhecidas, especialmente para a Estratégia Saúde da Família, são escassos os estudos voltados à organização da atenção nutricional no Sistema Único de Saúde. Objetivo Descrever e comparar a organização da Atenção Nutricional (AN) na Atenção Primária à Saúde em duas macrorregiões do estado de São Paulo, Brasil. Método O presente estudo transversal contemplou 115 serviços da Estratégia Saúde da Família, utilizando um instrumento estruturado, realizando uma análise descritiva dos dados e aplicando o teste exato de Fisher para verificar as associações entre a variável “região” e as demais variáveis de interesse. Resultados Foram realizadas 115 entrevistas com os gestores de 31 municípios. Verificou-se uma frequência maior de ações na RMBS, com diferenças estatisticamente significantes para as seguintes variáveis: papel do agente comunitário de saúde; avaliação individual do consumo alimentar, campanhas de vacinação e atividades grupais; mensuração do Índice de Massa Corporal na curva gestacional; apoio ao aleitamento materno; orientações sobre alimentação complementar e atendimento de equipe multidisciplinar para sobrepeso. Conclusão Foi observada uma predominância da AN na RMBS. Entretanto, existem limites a serem superados em ambas as regiões, demandando uma análise da qualidade dessas ações para alcançar a integralidade. reconhecidas Família (AN Paulo Brasil 11 estruturado região “região interesse 3 municípios Verificouse Verificou se RMBS saúde alimentar grupais gestacional materno sobrepeso Entretanto regiões integralidade 1

Abstract Background Although the importance of food and nutrition actions is recognized, especially in the Family Health Strategy, there are few studies on the organization of nutritional care in the Unified Health System. Objective To describe and compare the organization of Nutritional Care-AN in Primary Health Care in two macroregions of the State of São Paulo, Brazil. Method This is a cross-sectional study conducted in 115 Family Health Strategy services. A structured instrument was used. Descriptive data analysis and Fisher's exact test were performed to verify associations between the variable 'region' and those of interest. Results 115 interviews were conducted with managers from 31 municipalities. There was a higher frequency of actions at RMBS, with statistically significant differences for the following variables: role of community health agent; individual assessment of food intake, vaccination campaigns, and group activities; measurement of body mass index in the gestational curve; breastfeeding support; guidelines on complementary feeding and multidisciplinary team care for overweight. Conclusion AN predominated in RMBS. However, in both regions, there are limits to be overcome, requiring the analysis of the quality of these actions to achieve completeness. recognized System CareAN Paulo Brazil crosssectional cross sectional 11 services used Fishers Fisher s region 'region interest 3 municipalities RMBS variables agent intake campaigns activities curve support overweight However regions overcome completeness 1

https://doi.org/10.1590/1414-462x202331020411

13.

Validation of surgical care quality indicators in the Brazilian Unified Health System
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Caldas, Anna Cláudia Sales Gomes

; Araújo, Rafael Santiago de

; Medeiros, Paulo José

; Freitas, Marise Reis de

; Aledo, Victoriano Soria

; Gama, Zenewton André da Silva

Revista de Saúde Pública

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2023, Volume 57 elocation 27

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO OBJETIVO Validar um conjunto de indicadores para monitoramento da qualidade dos procedimentos cirúrgicos no Sistema Único de Saúde (SUS). MÉTODOS Estudo de validação desenvolvido em 5 etapas: 1) revisão de literatura; 2) priorização de indicadores; 3) validação de conteúdo dos indicadores por método de consenso RAND/UCLA; 4) estudo piloto para análise da confiabilidade; e 5) desenvolvimento de instrutivo para tabulação dos indicadores de resultado para monitoramento via sistemas de informações oficiais. RESULTADOS A partir da revisão de literatura, foram identificados 217 indicadores de qualidade cirúrgica. Os indicadores excluídos foram: indicadores baseados em evidências científicas inferiores a 1A, similares, específicos, que correspondiam a eventos sentinelas; e aqueles que não se aplicavam ao contexto do SUS. Foram submetidos ao consenso de especialistas 26 indicadores com alto nível de evidência científica. Foram validados 22 indicadores, dos quais 14 indicadores de processo e 8 indicadores de resultado com índice de validação de conteúdo ≥80%. Dos indicadores de processo validados, 6 foram considerados confiáveis substancialmente (Coeficiente de Kappa entre 0,6 e 0,8; p < 0,05) e 2 tiveram confiabilidade quase perfeita (coeficiente de Kappa > 0,8, p < 0,05), quando analisada a concordância interavaliador. Foi possível mensurar e estabelecer mecanismo de tabulação para TabWin para 7 indicadores de resultado. CONCLUSÃO O estudo contribui com o desenvolvimento de um conjunto de indicadores cirúrgicos potencialmente eficazes para o monitoramento da qualidade do cuidado e segurança do paciente nos serviços hospitalares do SUS. SUS . (SUS) etapas 1 literatura 3 RAND/UCLA RANDUCLA RAND UCLA 4 oficiais 21 cirúrgica 1A similares específicos sentinelas científica 80 ≥80% Coeficiente 06 0 0, 0,8 08 0,05 005 05 coeficiente 0,05, , interavaliador (SUS ≥80 0,0 00 ≥8 ≥

ABSTRACT OBJECTIVE To validate a set of indicators for monitoring the quality of surgical procedures in the Brazilian Unified Health System (SUS). METHODS Validation study developed in 5 stages: 1) literature review; 2) prioritization of indicators; 3) content validation of indicators by RAND/UCLA consensus method; 4) pilot study for reliability analysis; and 5) development of instruction for tabulation of outcome indicators for monitoring via official information systems. RESULTS From the literature review, 217 indicators of surgical quality were identified. The excluded indicators were: those based on scientific evidence lower than 1A, similar, specific, which corresponded to sentinel events; and those that did not apply to the SUS context. Twenty-six indicators with a high level of scientific evidence were submitted to expert consensus. Twenty-two indicators were validated, of which 14 process indicators and 8 outcome indicators with content validation index ≥80%. Of the validated process indicators, 6 were considered substantially reliable (Kappa coefficient between 0.6 and 0.8; p < 0.05) and 2 had almost perfect reliability (Kappa coefficient > 0.8, p < 0.05), when the inter-rater agreement was analyzed. One could measure and establish tabulation mechanism for TabWin for 7 outcome indicators. CONCLUSION The study contributes to the development of a set of potentially effective surgical indicators for monitoring the quality of care and patient safety in SUS hospital services. SUS. . (SUS) stages 1 review 3 RANDUCLA RAND UCLA method 4 analysis systems 21 identified 1A A similar specific events context Twentysix Twenty six Twentytwo two 80 ≥80% Kappa 06 0 0. 0.8 08 0.05 005 05 0.05, , interrater inter rater analyzed services (SUS ≥80 0.0 00 ≥8 ≥

https://doi.org/10.11606/s1518-8787.2023057004723

14.

Natural infection of Lutzomyia longipalpis (Lutz & Neiva, 1912) by Leishmania infantum in a municipality with a high incidence of visceral leishmaniasis in the Brazilian Midwest Lutz Neiva 1912 191 19 1
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Neitzke-Abreu, Herintha Coeto

; Andrade, Georgia Medeiros de Castro

; Almeida, Paulo Silva de

; Ribeiro, Gilmar Cipriano

; Ribeiro, Thaís Alves

; Barrios, D'Angela Maciel

; Pussi, Kamily Fagundes

; Andrade Filho, José Dilermando

; Dutra-Rêgo, Felipe

; Ovallos, Fredy Galvis

Revista da Sociedade Brasileira de Medicina Tropical

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2023, Volume 56 elocation e0259-2023

Abstract: En | Text: En | PDF: En

ABSTRACT Background: Here, Leishmania presence in sand flies from Três Lagoas, Mato Grosso do Sul, Brazil, after visceral leishmaniasis (VL) was investigated. Methods: In April 2022, two light traps were deployed within and around the residence for two days post-VL case report. Results: A total of 120 Lutzomyia longipalpis were collected. Suprapyloric flagellates were found in a female sand fly with eggs and residual blood during midgut dissection. Sequencing of ITS1 and cytb fragments confirmed Leishmania infantum DNA and identified Homo sapiens as the blood source, respectively. Conclusions: This study emphasizes the importance of monitoring sand flies in VL endemic areas. Background Here Lagoas Sul Brazil (VL investigated Methods 2022 postVL post report Results 12 collected dissection ITS source respectively Conclusions areas 202 1 20 2

https://doi.org/10.1590/0037-8682-0259-2023

15.

Diretriz da SBC sobre Diagnóstico e Tratamento de Pacientes com Cardiomiopatia da Doença de Chagas – 2023 202 20 2
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Marin-Neto, José Antonio

; Rassi Jr, Anis

; Oliveira, Gláucia Maria Moraes

; Correia, Luís Claudio Lemos

; Ramos Júnior, Alberto Novaes

; Luquetti, Alejandro Ostermayer

; Hasslocher-Moreno, Alejandro Marcel

; Sousa, Andréa Silvestre de

; Paola, Angelo Amato Vincenzo de

; Sousa, Antônio Carlos Sobral

; Ribeiro, Antonio Luiz Pinho

; Correia Filho, Dalmo

; Souza, Dilma do Socorro Moraes de

; Cunha-Neto, Edecio

; Ramires, Felix Jose Alvarez

; Bacal, Fernando

; Nunes, Maria do Carmo Pereira

; Martinelli Filho, Martino

; Scanavacca, Maurício Ibrahim

; Saraiva, Roberto Magalhães

; Oliveira Júnior, Wilson Alves de

; Lorga-Filho, Adalberto Menezes

; Guimarães, Adriana de Jesus Benevides de Almeida

; Braga, Adriana Lopes Latado

; Oliveira, Adriana Sarmento de

; Sarabanda, Alvaro Valentim Lima

; Pinto, Ana Yecê das Neves

; Carmo, Andre Assis Lopes do

; Schmidt, Andre

; Costa, Andréa Rodrigues da

; Ianni, Barbara Maria

; Markman Filho, Brivaldo

; Rochitte, Carlos Eduardo

; Macêdo, Carolina Thé

; Mady, Charles

; Chevillard, Christophe

; Virgens, Cláudio Marcelo Bittencourt das

; Castro, Cleudson Nery de

; Britto, Constança Felicia De Paoli de Carvalho

; Pisani, Cristiano

; Rassi, Daniela do Carmo

; Sobral Filho, Dário Celestino

; Almeida, Dirceu Rodrigues de

; Bocchi, Edimar Alcides

; Mesquita, Evandro Tinoco

; Mendes, Fernanda de Souza Nogueira Sardinha

; Gondim, Francisca Tatiana Pereira

; Silva, Gilberto Marcelo Sperandio da

; Peixoto, Giselle de Lima

; Lima, Gustavo Glotz de

; Veloso, Henrique Horta

; Moreira, Henrique Turin

; Lopes, Hugo Bellotti

; Pinto, Ibraim Masciarelli Francisco

; Ferreira, João Marcos Bemfica Barbosa

; Nunes, João Paulo Silva

; Barreto-Filho, José Augusto Soares

; Saraiva, José Francisco Kerr

; Lannes-Vieira, Joseli

; Oliveira, Joselina Luzia Menezes

; Armaganijan, Luciana Vidal

; Martins, Luiz Cláudio

; Sangenis, Luiz Henrique Conde

; Barbosa, Marco Paulo Tomaz

; Almeida-Santos, Marcos Antonio

; Simões, Marcos Vinicius

; Yasuda, Maria Aparecida Shikanai

; Moreira, Maria da Consolação Vieira

; Higuchi, Maria de Lourdes

; Monteiro, Maria Rita de Cassia Costa

; Mediano, Mauro Felippe Felix

; Lima, Mayara Maia

; Oliveira, Maykon Tavares de

; Romano, Minna Moreira Dias

; Araujo, Nadjar Nitz Silva Lociks de

; Medeiros, Paulo de Tarso Jorge

; Alves, Renato Vieira

; Teixeira, Ricardo Alkmim

; Pedrosa, Roberto Coury

; Aras Junior, Roque

; Torres, Rosalia Morais

; Povoa, Rui Manoel dos Santos

; Rassi, Sergio Gabriel

; Alves, Silvia Marinho Martins

; Tavares, Suelene Brito do Nascimento

; Palmeira, Swamy Lima

; Silva Júnior, Telêmaco Luiz da

; Rodrigues, Thiago da Rocha

; Madrini Junior, Vagner

; Brant, Veruska Maia da Costa

; Dutra, Walderez Ornelas

; Dias, João Carlos Pinto

Arquivos Brasileiros de Cardiologia

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2023, Volume 120 N. 6 elocation e20230269

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.36660/abc.20230269

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