Search | SciELO

Abstract Background Patients with immune-mediated rheumatic diseases (IMRDs) have been prioritized for COVID-19 vaccination to mitigate the infection severity risks. Patients with rheumatoid arthritis (RA) are at a high risk of severe COVID-19 outcomes, especially those under immunosuppression or with associated comorbidities. However, few studies have assessed the safety of the COVID-19 vaccine in patients with RA. Objective To evaluate the safety of vaccines against SARS-CoV-2 in patients with RA. Methods This data are from the study “Safety and Efficacy on COVID-19 Vaccine in Rheumatic Diseases,” a Brazilian multicentric prospective phase IV study to evaluate COVID-19 vaccine in IMRDs in Brazil. Adverse events (AEs) in patients with RA of all centers were assessed after two doses of ChAdOx1 (Oxford/AstraZeneca) or CoronaVac (Sinovac/Butantan). Stratification of postvaccination AEs was performed using a diary, filled out daily and returned at the end of 28 days for each dose. Results A total of 188 patients with RA were include, 90% female. CoronaVac was used in 109 patients and ChAdOx1 in 79. Only mild AEs were observed, mainly after the first dose. The most common AEs after the first dose were pain at the injection (46,7%), headache (39,4%), arthralgia (39,4%), myalgia (30,5%) and fatigue (26,6%), and ChAdOx1 had a higher frequency of pain at the injection (66% vs 32 %, p < 0.001) arthralgia (62% vs 22%, p < 0.001) and myalgia (45% vs 20%, p < 0.001) compared to CoronaVac. The more common AEs after the second dose were pain at the injection (37%), arthralgia (31%), myalgia (23%), headache (21%) and fatigue (18%). Arthralgia (41,4% vs 25%, p = 0.02) and pain at injection (51,4% vs 27%, p = 0.001) were more common with ChAdOx1. No serious AEs were related. With Regard to RA activity level, no significant difference was observed between the three time periods for both COVID-19 vaccines. Conclusion In the comparison between the two immunizers in patients with RA, local reactions and musculoskeletal symptoms were more frequent with ChAdOx1 than with CoronaVac, especially after the first dose. In summary, the AE occurred mainly after the first dose, and were mild, like previous data from others immunizing agents in patients with rheumatoid arthritis. Vaccination did not worsen the degree of disease activity. immunemediated immune mediated (IMRDs COVID19 COVID 19 COVID-1 risks (RA outcomes comorbidities However SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- Safety Diseases, Diseases Brazil (AEs ChAdOx Oxford/AstraZeneca OxfordAstraZeneca Oxford AstraZeneca (Oxford/AstraZeneca Sinovac/Butantan. SinovacButantan Sinovac/Butantan . Sinovac Butantan (Sinovac/Butantan) diary 18 include 90 female 10 79 46,7%, 467 46,7% , 46 7 (46,7%) 39,4%, 394 39,4% 39 4 (39,4%) 30,5% 305 30 5 (30,5% 26,6%, 266 26,6% 26 6 (26,6%) 66% 66 (66 3 % 0.001 0001 0 001 62% 62 (62 22 22% 45% 45 (45 20 20% 37%, 37 37% (37%) 31%, 31 31% (31%) 23%, 23 23% (23%) 21% 21 (21% 18%. 18% (18%) 41,4% 414 41 (41,4 25 25% 0.02 002 02 51,4% 514 51 (51,4 27 27% related level summary COVID1 1 COVID- SARS-CoV (Sinovac/Butantan 9 46,7 (46,7% 39,4 (39,4% 30,5 (30,5 26,6 (26,6% (6 0.00 000 00 (4 (37% (31% (23% (21 (18% 41,4 (41, 0.0 51,4 (51, 46, (46,7 39, (39,4 30, (30, 26, (26,6 ( (37 (31 (23 (2 (18 41, (41 0. 51, (51 (46, (39, (30 (26, (3 (1 (5 (46 (39 (26

https://doi.org/10.1186/s42358-024-00397-5

THE ROLE OF BOWEL DIARIES IN A “REAL-LIFE” SETTING REALLIFE REAL LIFE “REAL-LIFE
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

MENDES, Sofia Silva

; MATOS-SILVA, Maria

; LEAL, Tiago

; GONÇALVES, Raquel

; CAETANO, Ana Célia

Arquivos de Gastroenterologia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jan 2023, Volume 60 N. 1 Pages 21 - 29

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Contexto: Apesar das potenciais vantagens do diário intestinal como complemento à entrevista clínica, raros estudos avaliam a relevância da informação clínica obtida a partir de diários intestinais na prática clínica. Objetivo Os principais objetivos deste estudo foram avaliar o papel do diário intestinal como ferramenta diagnóstica numa consulta dedicada a patologia digestiva baixa. Métodos Foi realizado um estudo transversal, num período de 3 meses, em que no final das consultas os pacientes foram entrevistados relativamente a dados demográficos, antecedentes clínicos e hábitos e sintomas intestinais. Em seguida, foi solicitado o auto-preenchimento de um diário intestinal durante 2 semanas. Foram comparadas as respostas obtidas na entrevista clínica com os registos dos diários intestinais. Resultados: Cinquenta e três pacientes participaram no estudo. A frequência de evacuações reportada nas entrevistas clínicas e nos diários intestinais dos pacientes foi significativamente diferente (P=0,007). Verificou-se apenas uma concordância mínima entre a consistência das fezes descrita nas entrevistas e registada nos diários (κ=0,281). Em relação ao esforço evacuatório os pacientes sobrestimaram o seu esforço ao evacuar nas entrevistas (P=0,012). Adicionalmente, verificou-se que pacientes com doenças proctológicas descreveram menos evacuações nas suas entrevistas (P=0,033). A descrição do esforço durante a evacuação foi superestimada nas entrevistas de pacientes sem distúrbios proctológicos (P=0,028) e de pacientes com um nível mais elevado de educação (P=0,028). Conclusão: Globalmente verificaram-se discrepâncias entre a entrevista clínica e o diário intestinal dos pacientes em relação ao número de dejeções, à consistência das fezes e ao esforço evacuatório. Assim, esta ferramenta revelou-se uma potencial mais-valia na prática clínica diária, permitindo objetivar as queixas e consequentemente tratar os pacientes de forma mais adequada. Contexto baixa transversal meses demográficos seguida autopreenchimento auto preenchimento semanas Resultados P=0,007. P0007 P P=0,007 . 0 007 (P=0,007) Verificouse Verificou se κ=0,281. κ0281 κ κ=0,281 281 (κ=0,281) P=0,012. P0012 P=0,012 012 (P=0,012) Adicionalmente verificouse verificou P=0,033. P0033 P=0,033 033 (P=0,033) P=0,028 P0028 028 (P=0,028 P=0,028. Conclusão verificaramse verificaram dejeções Assim revelouse revelou maisvalia valia diária adequada P000 P=0,00 00 (P=0,007 κ028 κ=0,28 28 (κ=0,281 P001 P=0,01 01 (P=0,012 P003 P=0,03 03 (P=0,033 P=0,02 P002 02 (P=0,02 P00 P=0,0 (P=0,00 κ02 κ=0,2 (κ=0,28 (P=0,01 (P=0,03 (P=0,0 P0 P=0, κ0 κ=0, (κ=0,2 (P=0, P=0 κ=0 (κ=0, (P=0 P= κ= (κ=0 (P= (κ= (P (κ

ABSTRACT Background Despite the potential advantages of patients’ self-recordings of bowel habits in lower digestive disorders, few studies evaluate the relevance of clinical information obtained through bowel diaries in clinical practice. Objective The main objective of this study was to evaluate the role of bowel diaries as an auxiliary diagnostic tool in lower gastrointestinal disorders consultations. Methods In this cross-sectional study, at the end of their gastroenterology consultation, patients were questioned about their bowel habits and gastrointestinal symptoms. The bowel diary was then filled by the patients at home for 2 weeks. The data collected from the clinical interview and from the bowel diaries were analyzed. Results Fifty-three patients participated in the study. Patients underestimated the number of their bowel movements (BM) in the interviews compared with the bowel diaries (P=0.007). There was a poor agreement between stool consistencies described in the interviews and recorded in the diaries (k=0.281). Patients overestimated their straining during evacuation in the interviews compared with the diaries (P=0.012). Regarding the subgroups’ analysis, patients with proctological disorders described less BM in their interviews (P=0.033). Straining during evacuation was higher in the interviews of patients without proctological disorders (P=0.028) and in the interviews of more educated patients (P=0.028). Conclusion Overall, there were discrepancies between the clinical interview and the bowel diary regarding the number of BM, the stool consistency and straining. Bowel diaries are therefore a relevant instrument as a complement to the clinical interview to objectify patients’ complaints and treat functional gastrointestinal disorders more adequately. selfrecordings self recordings practice consultations crosssectional cross sectional consultation symptoms weeks analyzed Fiftythree Fifty three (BM P=0.007. P0007 P P=0.007 . 0 007 (P=0.007) k=0.281. k0281 k k=0.281 281 (k=0.281) P=0.012. P0012 P=0.012 012 (P=0.012) subgroups analysis P=0.033. P0033 P=0.033 033 (P=0.033) P=0.028 P0028 028 (P=0.028 P=0.028. Overall adequately P000 P=0.00 00 (P=0.007 k028 k=0.28 28 (k=0.281 P001 P=0.01 01 (P=0.012 P003 P=0.03 03 (P=0.033 P=0.02 P002 02 (P=0.02 P00 P=0.0 (P=0.00 k02 k=0.2 (k=0.28 (P=0.01 (P=0.03 (P=0.0 P0 P=0. k0 k=0. (k=0.2 (P=0. P=0 k=0 (k=0. (P=0 P= k= (k=0 (P= (k= (P (k

https://doi.org/10.1590/s0004-2803.202301000-04

Effect of Lubricant Use on Cervicovaginal Cytology – What's the Evidence? Whats What s Evidence
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Santos, Diana Magalhães dos

; Matos, Maria Beatriz Freire Oliveira Coelho de

; Sousa, Ana Raquel Borges

; Fertusinhos, Francisco Correia de Almeida

; Pendás, Rosa Maria Couceiro

Revista Brasileira de Ginecologia e Obstetrícia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 45 N. 11 Pages 724 - 728

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo Determinar se o uso de gel lubrificante no espéculo durante o exame de citologia cervicovaginal interfere com os resultados obtidos e se diminui o desconforto relatado por pacientes. Fontes de dados Foi realizada uma revisão sistemática segundo as recomendações do Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), com pesquisa nas bases de dados Pubmed/Medline, Scielo, Cochrane Library, Embase, de artigos publicados entre janeiro de 2011 e julho de 2022. Utilizaram-se as palavras-chave citologia, espéculo, lubrificante, resultado e dor. Seleção dos estudos A pesquisa inicial resultou em 306 artigos, dos quais foram excluídos três por se encontrarem duplicados, 257 após a leitura do título e do resumo e 41 após a leitura integral. Assim, foram selecionados cinco artigos para o estudo: quatro ensaios clínicos aleatorizados e uma metanálise. Coleta de dados A seleção dos artigos foi realizada por dois investigadores. Os cinco artigos selecionados foram lidos na íntegra e submetidos a uma análise comparativa. Síntese dos dados O rastreio através da citologia cervicovaginal permite um diagnóstico precoce e redução da mortalidade associada, mas a sua realização pode estar associada a dor. Uma pequena quantidade de gel lubrificante aquoso pode ser utilizada no espéculo para diminuir o desconforto associado à realização da citologia cervicovaginal. Conclusão A utilização de gel lubrificante não está associada a alteração do resultado da citologia e diminui o desconforto associado à sua introdução na vagina. pacientes MetaAnalyses Meta Analyses PRISMA, PRISMA , (PRISMA) PubmedMedline Pubmed Medline Pubmed/Medline Scielo Library Embase 201 2022 Utilizaramse Utilizaram palavraschave palavras chave dor 30 duplicados 25 4 integral Assim estudo metanálise investigadores comparativa vagina (PRISMA 20 202 3 2

Abstract Objective To determine if the use of lubricating gel on the speculum during the cervicovaginal cytology examination interferes with the results obtained, as well as whether it reduces reported discomfort in patients. Data sources A systematic review was carried out according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations, with a search in the Pubmed/Medline, Scielo, Cochrane Library, Embase databases of articles published between January 2011 and May 2022. The keywords used were cytology, speculum, lubricant, result, and pain. Selection of studies The initial search resulted in 306 articles, of which were excluded three because they were duplicates, 257 after reading the title and abstract and 41 after reading the full text. Thus, five articles were selected for the study: four randomized clinical trials and one metanalysis. Data collection The selection of articles was performed by two investigators. The 5 selected articles were read in full and submitted to a comparative analysis. Data synthesis Screening through cervicovaginal cytology allows for early diagnosis and reduction of associated mortality, but the procedure can be associated with pain. A small amount of aqueous lubricating gel in the speculum can be used to reduce the discomfort associated with performing cervicovaginal cytology. Conclusion The use of lubricating gel in the speculum does not seem to be associated with a change in the cytology result and reduces the discomfort associated with its insertion into the vagina. obtained patients MetaAnalyses Meta Analyses PRISMA (PRISMA recommendations PubmedMedline Pubmed Medline Pubmed/Medline Scielo Library 201 2022 lubricant pain 30 duplicates 25 4 text Thus study metanalysis investigators analysis mortality vagina 20 202 3 2

https://doi.org/10.1055/s-0043-1776025

Participação pública em saúde e Covid-19 em Portugal Covid19 Covid 19 Covid-1 Covid1 1 Covid-
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Matos, Ana Raquel

; Craveiro, Isabel

Saúde em Debate

Journal Metrics
- Sobre o periódico
- SciELO Analytics

nov 2022, Volume 46 N. spe4 Pages 107 - 119

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Nas últimas décadas, o tema da participação pública em processos de decisão tem estado presente nas agendas políticas, com mais ou menos centralidade, em vários contextos democráticos do mundo. No campo da saúde, a participação pública apresenta-se como estratégia política com potencialidades para garantir maior corresponsabilização entre os atores envolvidos e para incrementar a transparência dos serviços, sendo enfatizada como boa prática que deve ser implementada em prol da qualidade das decisões, mas também de decisões que sejam orientadas para os reais problemas das populações. A pandemia da Covid-19 trouxe pressões adicionais aos sistemas de saúde, constituindo-se como contexto propício à análise da participação cidadã nos processos de decisão que enquadram problemas de saúde na sua relação com a pandemia. Este ensaio apresenta uma análise exploratória sobre a evolução das práticas de participação cidadã nas políticas de saúde em Portugal, destacando alguns dos seus desafios atuais e futuros. Procura-se, assim, compreender como a pandemia teve ressonância na forma como a participação em saúde vinha decorrendo no País, aferindo se, em um período global de crise com características singulares, a pandemia, enquanto problema coletivo, distendeu ou contraiu essas práticas participativas. décadas centralidade mundo apresentase se serviços populações Covid19 Covid 19 Covid-1 constituindose constituindo Portugal futuros Procurase, Procurase Procura Procura-se assim País singulares coletivo participativas Covid1 1 Covid-

ABSTRACT In the last decades, public participation in decision-making processes has been an ongoing theme, assuming more or less centrality, within the political agendas in several democratic contexts around the world. In the health domain, public participation has been considered a political strategy with the potential of ensuring greater co-responsibility among the actors involved, as well as to increase health services’ transparency, thus being emphasized as one of the best practices that should be implemented towards the quality of decisions, especially those oriented to the real health problems of the populations. The COVID-19 pandemic brought additional pressures to health systems, constituting itself as a conducive context to the analysis of citizen participation in health decision-making processes. This essay presents an exploratory analysis on the evolution of citizen participation practices in health policies in Portugal, highlighting some of its current and future challenges. The present analysis aims to understand how the pandemic resonated in the way in which participation in the health domain had been carried out in the country, assessing whether, in a singular global period of crisis, the pandemic as a collective problem expanded or contracted these participatory practices. decades decisionmaking decision making theme centrality world coresponsibility co responsibility involved services transparency decisions populations COVID19 COVID 19 COVID-1 systems Portugal challenges country whether crisis COVID1 1 COVID-

https://doi.org/10.1590/0103-11042022e408

[SciELO Preprints] - Public participation in health and Covid-19 in Portugal
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Matos, Ana Raquel Craveiro, Isabel

Journal Metrics
- Sobre o periódico
- SciELO Analytics

Publication date: 2022-03-07

Abstract: En Pt

In the last decades, public participation in decision-making processes has been and ongoing theme, assuming more or less centrality, within the political agendas in several democratic contexts around the world. In the health domain, public participation has been considered a political strategy with the potential of ensuring greater co-responsibility among the actors involved, as well as to increase health services’ transparency. In this way, it has been emphasized as a best practice that should be implemented towards the quality of decisions, especially those oriented to the real health problems of the populations. The COVID-19 pandemic brought additional pressures to health systems, which constitutes itself as a conducive context to the analysis of citizen participation in health decision-making processes. This essay presents an exploratory analysis on the evolution of citizen’s participation practices in health policies in Portugal, highlighting some of its current and future challenges. The present analysis aims to understand how the pandemic had resonance in the way in which participation in the health domain had been carried out in the country, assessing whether, in a singular global period of crisis, the pandemic as a collective problem expanded or contracted these participatory practices.

Nas últimas décadas, o tema da participação pública em processos de decisão tem estado presente nas agendas políticas, com mais ou menos centralidade, em vários contextos democráticos do mundo. No campo da saúde, a participação pública apresenta-se como estratégia política com potencialidades para garantir maior corresponsabilização entre os atores envolvidos e para incrementar a transparência dos serviços, sendo enfatizada como boa prática que deve ser implementada em prol da qualidade das decisões, mas também de decisões que sejam orientadas para os reais problemas das populações.nbsp;A pandemia COVID-19 trouxe pressões adicionais aos sistemas de saúde, constituindo-se como contexto propício à análise da participação cidadã nos processos de decisão que enquadram problemas de saúde na sua relação com a pandemia. nbsp;Este ensaio apresentanbsp;uma análise exploratória sobre a evolução das práticas de participação cidadã nas políticas de saúde em Portugal, destacando alguns dos seus desafios atuais e futuros. Procura-se, assim,nbsp;compreender como a pandemia teve ressonância na forma como a participação em saúde vinha decorrendo no país, aferindo se, num período global de crise com características singulares, a pandemia enquanto problema coletivo distendeu ou contraiu estas práticas participativas.

https://doi.org/10.1590/SciELOPreprints.3735

Participação pública em saúde e Covid-19 em Portugal
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Matos, Ana Raquel

; Craveiro, Isabel

Saúde em Debate

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2022, Volume 46 N. spe4 Pages 107 - 119

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/0103-11042022e408

Association between calcium/magnesium ratio and insulin resistance in women with obesity and normal-weight women
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Clímaco-Cruz, Kyria Jayanne

; Oliveira, Ana Raquel Soares de

; Silva-Morais, Jennifer Beatriz

; Melo, Stéfany Rodrigues de Sousa

; Santos, Loanne Rocha dos

; Fontenelle, Larissa Cristina

; Freitas, Suelem Torres de

; Silva, Vladimir Costa

; Nery-Costa, Carlos Henrique

; Simeone-Henriques, Gilberto

; Matos Neto, Emídio Marques de

; Marreiro, Dilina do Nascimento

Revista chilena de nutrición

Journal Metrics
- Sobre o periódico
- SciELO Analytics

oct 2021, Volume 48 N. 5 Pages 758 - 767

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT The aim of this study was to evaluate the association between the calcium/magnesium (Ca/Mg) ratio and insulin resistance in women with obesity and normal-weight women. This was a cross-sectional study with 128 women (62 women with obesity and 66 normal-weight women). We measured dietary minerals intake and analyzed magnesium and calcium biomarkers. Ca/Mg ratio in diet, plasma and urine were calculated. We have evaluated glycemic parameters. Women with obesity had low dietary magnesium, reduced plasma and erythrocyte magnesium concentrations, and elevated urinary magnesium excretion. Plasma calcium concentration was lower and urinary calcium excretion was higher in patients with obesity than in the normal-weight group. Dietary magnesium and calcium intake per kilogram of body weight per day was lower in obese women than in the control group. Ca/Mg ratio in plasma and urine were elevated in women with obesity. We found a significant correlation among magnesium biomarkers and calcium parameters. Ca/Mg ratio seems to be associated with insulin resistance in obese women.

RESUMEN El objetivo de este estudio fue evaluar la asociación entre la relación Ca/Mg y la resistencia a la insulina en mujeres con obesidad y en mujeres con peso normal. El diseño del estudio fue transversal y participaron 128 mujeres (62 mujeres con obesidad y 66 mujeres con peso normal). Se analizó la ingesta de minerales en la dieta y se realizaron análisis de biomarcadores de magnesio y calcio. Se calculó la relación Ca/Mg en dieta, plasma y orina y se evaluaron los parámetros glicémicos. Las mujeres con obesidad tenían niveles bajos de magnesio en la dieta, concentraciones reducidas de magnesio en plasma y eritrocitos, y excreción urinaria de magnesio elevada. La concentración plasmática de calcio fue menor en pacientes con obesidad, y la excreción urinaria de calcio fue mayor que en el grupo de mujeres con peso normal. La ingesta dietética de magnesio y calcio por kilogramo de peso corporal por día fue menor en las mujeres con obesidad, que en el grupo control. La relación Ca/Mg en plasma y orina estaba elevada en mujeres con obesidad. Se encontró una correlación significativa entre los biomarcadores de magnesio y los parámetros de calcio. La relación Ca / Mg parece estar asociada con la resistencia a la insulina en mujeres con obesidad.

224 downloads

Ontologias do Antropoceno: Crise climática, respostas sociopolíticas e tecnologias emergentes
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Carvalho, António

; Ferreira, Vera

; Matos, Ana Raquel

Forum Sociológico

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jun 2021, N. 38 Pages 5 - 13

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O Antropoceno é uma época geológica proposta para ilustrar o impacto humano no sistema terrestre, exemplificado pelas alterações climáticas. Recorrendo a literatura no âmbito dos estudos de ciência e tecnologia, este artigo reflete sobre a heterogeneidade ontológica do Antropoceno, analisando como diferentes respostas sociais, políticas e tecnológicas são mobilizadas para fazer face aos desafios das alterações climáticas. O artigo analisa três estudos de caso que ilustram a heterogeneidade ontológica do Antropoceno : políticas europeias e nacionais em matéria de ação climática ; o movimento de transição, focado em ações à escala local para a descarbonização das sociedades ; a geoengenharia como tecnologia emergente de manipulação climática. Neste trabalho argumentamos que a diversidade de visões, práticas e intervenções associadas aos estudos de caso reforçam o carácter político e controverso do Antropoceno, colocando novos desafios às ciências sociais.

Abstract The Anthropocene is a proposed geological epoch to illustrate the human impact on Earth systems - exemplified by climate change. Supported by literature within science and technology studies, this article reflects on the ontological heterogeneity of the Anthropocene, analyzing how different social, political and technological proposals are mobilized to face the challenges of climate change. The article delves into three case studies that illustrate the ontological heterogeneity of the Anthropocene : European and national policies regarding climate change ; the Transition Movement, focused on local actions to foster low carbon transitions ; emerging technologies of climate manipulation - geoengineering. We argue that the diversity of visions, practices and interventions related to the case studies reinforce the political and controversial dimensions of the Anthropocene, posing new challenges for the social sciences.

https://doi.org/10.4000/sociologico.9693 62 downloads

Intensive support recommendations for critically-ill patients with suspected or confirmed COVID-19 infection
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Corrêa, Thiago Domingos

; Matos, Gustavo Faissol Janot de

; Bravim, Bruno de Arruda

; Cordioli, Ricardo Luiz

; Garrido, Alejandra del Pilar Gallardo

; Assuncao, Murillo Santucci Cesar de

; Barbas, Carmen Silvia Valente

; Timenetsky, Karina Tavares

; Rodrigues, Roseny dos Reis

; Guimarães, Hélio Penna

; Rabello Filho, Roberto

; Lomar, Frederico Polito

; Scarin, Farah Christina de La Cruz

; Batista, Carla Luciana

; Pereira, Adriano José

; Guerra, João Carlos de Campos

; Carneiro, Bárbara Vieira

; Nawa, Ricardo Kenji

; Brandão, Rodrigo Martins

; Pesaro, Antônio Eduardo Pereira

; Silva Júnior, Moacyr

; Carvalho, Fabricio Rodrigues Torres de

; Silva, Cilene Saghabi de Medeiros

; Almeida, Ana Claudia Ferraz de

; Franken, Marcelo

; Pesavento, Marcele Liliane

; Eid, Raquel Afonso Caserta

; Ferraz, Leonardo José Rolim

einstein (São Paulo)

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2020, Volume 18 elocation eAE5793

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Em dezembro de 2019, uma série de pacientes com pneumonia grave foi identificada em Wuhan, província de Hubei, na China. Esses pacientes evoluíram para síndrome respiratória aguda grave e síndrome do desconforto respiratório agudo. Posteriormente, a COVID-19 foi atribuída a um novo betacoronavírus, o coronavírus da síndrome respiratória aguda grave 2 (SARS-CoV-2). Cerca de 20% dos pacientes com diagnóstico de COVID-19 desenvolvem formas graves da doença, incluindo insuficiência respiratória aguda hipoxêmica, síndrome respiratória aguda grave, síndrome do desconforto respiratório agudo e insuficiência renal aguda e requerem admissão em unidade de terapia intensiva. Não há nenhum ensaio clínico randomizado controlado que avalie potenciais tratamentos para pacientes com infecção confirmada pela COVID-19 no momento da publicação destas recomendações de tratamento. Dessa forma, essas recomendações são baseadas predominantemente na opinião de especialistas (grau de recomendação de nível C).

ABSTRACT In December 2019, a series of patients with severe pneumonia were identified in Wuhan, Hubei province, China, who progressed to severe acute respiratory syndrome and acute respiratory distress syndrome. Subsequently, COVID-19 was attributed to a new betacoronavirus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Approximately 20% of patients diagnosed as COVID-19 develop severe forms of the disease, including acute hypoxemic respiratory failure, severe acute respiratory syndrome, acute respiratory distress syndrome and acute renal failure and require intensive care. There is no randomized controlled clinical trial addressing potential therapies for patients with confirmed COVID-19 infection at the time of publishing these treatment recommendations. Therefore, these recommendations are based predominantly on the opinion of experts (level C of recommendation).

https://doi.org/10.31744/einstein_journal/2020ae5793 23244 downloads

10.

Comment to: Intensive support recommendations for critically-ill patients with suspected or confirmed COVID-19 infection
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Corrêa, Thiago Domingos

; Matos, Gustavo Faissol Janot de

; Bravim, Bruno de Arruda

; Cordioli, Ricardo Luiz

; Garrido, Alejandra del Pilar Gallardo

; Assuncao, Murillo Santucci Cesar de

; Barbas, Carmen Silvia Valente

; Timenetsky, Karina Tavares

; Rodrigues, Roseny dos Reis

; Guimarães, Hélio Penna

; Rabello Filho, Roberto

; Lomar, Frederico Polito

; Scarin, Farah Christina de La Cruz

; Batista, Carla Luciana

; Pereira, Adriano José

; Guerra, João Carlos de Campos

; Carneiro, Bárbara Vieira

; Nawa, Ricardo Kenji

; Brandão, Rodrigo Martins

; Pesaro, Antônio Eduardo Pereira

; Silva Júnior, Moacyr

; Carvalho, Fabricio Rodrigues Torres de

; Silva, Cilene Saghabi de Medeiros

; Almeida, Ana Claudia Ferraz de

; Franken, Marcelo

; Pesavento, Marcele Liliane

; Eid, Raquel Afonso Caserta

; Ferraz, Leonardo José Rolim

einstein (São Paulo)

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2020, Volume 18 elocation eCE5931

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.31744/einstein_journal/2020ce5931 214 downloads

11.

Quando nem a palavra é de prata, nem o silêncio é de ouro: Análise de conflitos sobre mineração em Portugal
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Matos, Ana Raquel

; Fernandes, Lúcia

Sociologia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jun 2019, Volume 37 Pages 11 - 30

Este artículo analiza ocho casos de conflictos mineros en Portugal. El trabajo destaca las acciones de protesta desencadenadas y los impactos que éstas produjeron. Metodológicamente se privilegia el análisis documental. Los resultados revelan que la protesta colectiva es utilizada por las poblaciones afectadas para transmitir sus percepciones y argumentos sobre los problemas y hacer visibles las situaciones vividas. Las protestas realizadas confirieron mayor visibilidad a las particularidades de cada conflicto y produjeron cambios legislativos, aunque puntuales y específicos de ciertos casos.

Este artigo analisa oito casos de conflitos de mineração em Portugal, destacando as ações de protesto desencadeadas e os impactos que produziram. Metodologicamente privilegia a análise documental. Os resultados revelam a ação pelo protesto como recurso para as populações afetadas transmitirem as suas perceções e argumentos sobre os problemas enfrentados e tornarem visíveis as situações vividas. Os protestos realizados produziram alterações legislativas, embora pontuais e específicas de certos casos, e conferiram maior visibilidade às particularidades de cada caso.

Cet article analyse huit cas de conflits miniers au Portugal. Le travail met en évidence les actions de contestation déclenchées et les impacts qu'elles ont produits. La méthodologie d'analyse documentaire a été privilégiée. Les résultats révèlent que la mobilisation collective est un moyen pour les populations affectées de transmettre leurs perceptions et arguments et pour rendre visibles les situations vécues. Les manifestations ont conduit à des changements législatifs, bien que ponctuels et spécifiques à certains cas, et ont rendu visibles les particularités de chaque conflit.

This paper analyzes eight cases of mining conflicts in Portugal, focusing on the protest actions triggered, as well as the impacts they have produced. Methodologically, documentary analysis was undertaken. The results revealed collective action as the available resource for the affected populations to communicate their perceptions and arguments about the problems felt and to make their lived situations visible. Protest actions registered were able to produce legislative changes, even concerning specific situations, and gave visibility to the particularities of each case.

https://doi.org/10.21747/08723419/soc37a1 474 downloads

12.

Antimicrobial Potential of Natural and Semi-Synthetic ent-Kaurane and ent-Pimarane Diterpenes against Clinically Isolated Gram-Positive Multidrug-Resistant Bacteria
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Soares, Ana Carolina F.

; Matos, Priscilla M.

; Silva, Karime F. da

; Martins, Carlos H. G.

; Veneziani, Rodrigo C. S.

; Ambrósio, Sérgio R.

; Dias, Herbert J.

; Santos, Raquel A. dos

; Heleno, Vladimir C. G.

Journal of the Brazilian Chemical Society

Journal Metrics
- Sobre o periódico
- SciELO Analytics

feb 2019, Volume 30 N. 2 Pages 333 - 341

Abstract: En | Text: En | PDF: En

In this work, a search for antimicrobial agents against multi-drug resistant (MDR) bacteria was undertaken. It involved two natural diterpenes of different basic skeletons, named ent-kaurenoic acid and ent-pimaradienoic acid, that were used as precursors to access 28 semi-synthetic derivatives that were also submitted to biological assays. All 30 substances were assayed against a set of seven clinically isolated MDR bacteria, including three Staphylococcus aureus strains. Results classified both natural compounds as promising bactericidal antimicrobial agents against these MDR bacteria, especially for their performance in time-kill curve assay, improving on the positive control vancomycin. Moreover, di-hydro ent-pimaradienoic acid, obtained as one of the derivatives, also displayed promising minimum inhibitory concentration (MIC) values against the microorganism set, proving optimum activity against S. aureus strains. Thereby, this work also yielded a promising semi-synthetic bacteriostatic antimicrobial agent against MDR S. aureus. Furthermore, the study was carried out with 30 structures in order to verify the veracity and scope of Urzúa’s hypothesis about the structure-activity relationship between diterpenes and antimicrobial action. Our results are 93% in agreement with this hypothesis.

https://doi.org/10.21577/0103-5053.20180182 1100 downloads

13.

Environmental effects and repeatability of the follicular diameter in mares
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Rua, Miguel Alejandro Silva

; Quirino, Celia Raquel

; Matos, Luis Fonseca

; Rodrigues, Ana Cláudia Cerqueira

; Bartholazzi Junior, Aylton

Revista Brasileira de Zootecnia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2019, Volume 48 elocation e20190047

Abstract: En | Text: En | PDF: En

ABSTRACT The objective of this study was to evaluate the effect of environment on follicular diameter and repeatability of the size of preovulatory follicles of mares. Temperature, rainfall, and photoperiod were measured, and their effects were evaluated on follicular dynamics. Data were studied by analysis of variance of follicular size and environment traits. During the five years, 7% double ovulations and 159 anovulatory follicles were recorded. Mean preovulatory follicle diameters of left and right ovaries were 39.3±3.8 and 39.2±3.5 mm respectively. There was no effect of evaluation year on follicular diameter. Reproduction season affected the right preovulatory follicle diameter. There was no effect of temperature and rainfall on follicular diameter. Repeatability values of the preovulatory follicular diameter were low. In the subtropical climate studied, temperature and rainfall caused no effect on follicular dynamics, and photoperiod had only a small effect on dominant preovulatory follicular diameter. Repeatability of follicular diameter was low, so this characteristic should be evaluated daily to predict ovulation and the optimal time to inseminate mares.

https://doi.org/10.1590/rbz4820190047 380 downloads

14.

A emergência do sujeito participativo: interseções entre ciência, política e ontologia
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Nunes, João Arriscado

; Costa, Daniel Neves da

; Carvalho, António

; Matos, Ana Raquel

Sociologias

Journal Metrics
- Sobre o periódico
- SciELO Analytics

aug 2018, Volume 20 N. 48 Pages 162 - 187

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Nas últimas décadas, os dispositivos de participação pública têm registado um crescimento exponencial. Estes procedimentos podem assumir uma diversidade de configurações, gerando um número de questões teóricas e práticas. A partir da análise de dois estudos de caso - grupos de discussão sobre nanotecnologias em Coimbra, Portugal, e Conselhos de Saúde em Belo Horizonte, Brasil - este artigo oferece uma reflexão sobre as questões políticas e metodológicas relacionadas com a conceção e implementação de procedimentos participativos. A análise explora a emergência do cidadão participativo, associado a capacidades e formas de conhecimento que permitem a intervenção em espaços deliberativos. Argumenta-se que os dispositivos participativos e os processos de subjetivação estão interligados, dialogando-se com as reflexões de Foucault sobre subjetividade e com abordagens pós-humanistas no âmbito dos Estudos Sociais de Ciência e Tecnologia. Os dois estudos de caso ilustram como os procedimentos participativos geram novas capacidades epistémicas, retóricas e normativas associadas à habilitação e subjetivação dos participantes. Dessa forma, o artigo explora os aspetos políticos das práticas, metodologias e processos que suportam o envolvimento de cidadãos em ciência, tecnologia e saúde, contribuindo para a desnaturalização do sujeito participativo e para o reconhecimento da dimensão performativa das ciências sociais.

Abstract Over the last few decades, there has been a proliferation of devices of public participation. Those procedures can assume a wide range of configurations, generating a number of practical and theoretical issues. Drawing upon the analysis of two case studies - focus groups on nanotechnologies in Coimbra, Portugal, and Health Councils in Belo Horizonte, Brazil - this article reflects on political and methodological issues related to the conception and implementation of participatory devices. Our analysis explores the emergence of the participatory subject, intertwined with abilities and forms of knowledge that allow intervention in deliberative spaces. It is argued that participatory devices and subjectification processes are intertwined, following Foucault’s reflections on subjectivity and post-humanist approaches within Science and Technology Studies. The two case studies illustrate how participatory processes trigger new epistemic, rhetorical and normative capacities linked to the habilitation and subjectification of participants. In that sense, the article explores the political aspects of practices, methodologies and processes that support public engagement with science, technology and health, leading to the denaturalization of the participatory subject and to the recognition of the performative dimension of social sciences.

https://doi.org/10.1590/15174522-020004811 1170 downloads

15.

Treatment of digital ulcers in systemic sclerosis: Case series study of thirteen patients and discussion on outcome
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Abuowda, Yahia

; Almeida, Raquel Sousa

; Oliveira, Ana Alves

; Pego, Petra

; Santos, Cristina

; Matos-Costa, João

Revista da Associação Médica Brasileira

Journal Metrics
- Sobre o periódico
- SciELO Analytics

may 2017, Volume 63 N. 5 Pages 422 - 426

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: As úlceras digitais (UD) são complicações incapacitantes e recorrentes, associadas a menor qualidade de vida e maior mortalidade na esclerose sistêmica (ES). O tratamento baseia-se em antagonizar os mecanismos fisiopatológicos em causa. Objetivo: Descrever uma amostra de doentes com diagnóstico de ES e UD, o tratamento, as complicações e os resultados clínicos. Método: Série de 48 casos diagnosticados com ES, critérios de classificação ACR-EULAR 2013, seguidos entre 1999 e 2015, dos quais 13 apresentavam UD. O protocolo aplicado incluía ciclos de 21 dias de alprostadil podendo ser repetidos no caso de não existir cicatrização. Nos casos em que houve cicatrização foi iniciado bosentano. Resultados: No tratamento das UD, 12 doentes realizaram prostaciclina endovenosa, com necessidade de tratamentos repetidos em sete doentes. Doze doentes foram posteriormente tratados com bosentano, com recorrência de UD em três doentes, um deles com presença de anti-B2-GPI. Quatro doentes ficaram com cicatrizes e em três houve amputação digital, sendo casos de diagnóstico tardio. Conclusão: Os doentes mais jovens tiveram melhores resultados, possivelmente em razão de melhorias globais nos cuidados de saúde prestados e de referenciação precoce. A toxicidade dos antagonistas dos receptores da endotelina deve ser monitorizada, sobretudo em doentes com exposição prévia a drogas hepatotóxicas.

Summary Introduction: In systemic sclerosis (SSc), digital ulcers (DU) are debilitating and recurrent. They are markers of prognosis and are associated with disability and mortality. Treatment strategies have been developed to block the proposed mechanisms of this complication. Objective: Clinical description of a population of SSc patients with DU, treatment, complications and outcome. Method: Analysis of 48 SSc patients meeting 2013 ACR-EULAR criteria, followed between 1999-2015; 13 patients had DU. Treatment protocol applied included cycles of 21 days of alprostadil, which can be repeated in the absence of DU healing. After DU healing, bosentan was initiated. Results: DU healing was achieved with intravenous prostanoid in 12 patients; seven patients required repeated treatment for DU healing. Twelve patients were later treated with bosentan; three of them experienced recurrence of DU, while one was anti-B2-GPI positive. Four patients had soft tissue loss and three other suffered digital amputation, these being late diagnosis. Conclusion: Younger patients and early referrals had better outcomes. Endothelin receptor antagonist toxicity should be monitored, particularly in patients previously exposed to hepatotoxic drugs.

https://doi.org/10.1590/1806-9282.63.05.422 2472 downloads

Showing

itens per page

Page of 3 Next

Select one or more results

All Alphabetic

Results

Comparative chart Download CSV

Statistics of

Send result

To*

Use ; (semicolon) to insert more emails.

Send to email

This page

Selected records

All references (max. 300)

Your email

Subject

Comments

Export format:

RIS (for EndNote, ProCite, Reference Manager, RefWorks, Citavi, etc.)

BibTeX

Citation

CSV (for Excel, etc)

Export:

This page

Selected itens

All references (max. 2000)

Sem resultados

No documents were found for your search

Glossary and search help

You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.

For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

See below the complete list of search indexes that can be used:

Index code	Element
ti	article title
au	author
kw	article keywords
subject	subject (title words, abstract and keywords)
ab	abstract
ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

SciELO - Scientific Electronic Library Online
Rua Dr. Diogo de Faria, 1087 – 9º andar – Vila Clementino 04037-003 São Paulo/SP - Brasil
Email: scielo@scielo.org

All the contents of this site www.scielo.br, except where otherwise noted, is licensed under a Creative Commons Attribution License.
more »