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ABSTRACT Harvest delay can alter the physiological and sanitary quality of sorghum seeds due to the longer exposure time of seeds to adverse environmental conditions in the field. In this study, we investigated the impact of delayed Sorghum sp. harvest on the physiological and sanitary quality of seeds in four hybrids grown in the tropical soil of the Brazilian Cerrado region. Plants from four Sorghum sp. hybrids (IPA SUDAN 4202, BRS 658, BRS 810, and BRS 373) were grown and submitted to four seed harvest periods (0, 7, 14, and 21 days after stage 9 - seed physiological maturity). The treatments were arranged in a completely randomized block design in a 4 × 4 factorial, with four replicates. At each harvest period, the thousand-seed weight, water content, first count of the germination test, germination, seedling emergence, emergence speed index, seedling dry matter, accelerated aging, electrical conductivity, and sanitary quality of seeds were determined. Seeds of higher physiological and sanitary quality of the IPA SUDAN 4202 and BRS 658 sorghum hybrids can be obtained when the harvest is carried out up to 7 days after the physiological maturity stage. However, the delay in seed harvesting at 14 and 21 days after physiological maturity results in a higher incidence of Colletotrichum sp., Curvularia sp., Rhizoctonia sp., and Alternaria sp. on the seeds of these hybrids. Delaying the harvest of sorghum seeds from 7 days after the physiological maturity stage compromises seed vigor and viability and increases the incidence of pathogens.

https://doi.org/10.5935/1806-6690.20230068

Clinical epidemiological and laboratory investigation in co-infection with COVID-19 and tuberculosis coinfection co infection COVID19 COVID 19 COVID-1 COVID1 1 COVID-
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Belchior, Ana Carulina Guimarães

; Freitas Neto, Antônio Martins de

; Gusmao, Grassyelly Silva

; Santos, Evelin Jaqueline Lima dos

; Lemos, Everton Ferreira

; Pompilio, Mauricio Antonio

; Volpe-Chaves, Cláudia Elizabeth

; Brito, Eliana da Costa Alvarenga de

; Oliveira, Everton Falcão de

; Carreiro, Ana Caroline Blanco

; Paniago, Anamaria Mello Miranda

Revista do Instituto de Medicina Tropical de São Paulo

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2024, Volume 66 elocation e65

Abstract: En | Text: En | PDF: En

ABSTRACT Currently, COVID-19 and tuberculosis (TB) are the deadliest infectious diseases worldwide. Their synergy, form of presentation, morbidity, and mortality are data that have been scarcely explored. Thus, this study aimed to characterize the clinical, epidemiological, and laboratory factors of this co-infection and to analyze the factors associated with the active TB among COVID-19 cases. A case-control study was conducted with a retrospective survey of 21 laboratory-confirmed COVID-19/TB co-infected patients (case group) and 21 COVID-19 patients (control group). The study included participants from eight hospitals in Campo Grande city, capital of Mato Grosso do Sul State, Brazil, from March 2020 to March 2022. Association analysis and binomial logistic regression were employed with statistical significance set at p≤0.05. From the 21 identified cases of COVID-19/TB co-infection, we found a more frequent association with HIV infection than the control-group, without worsening the outcome. COVID-19/TB patients had less dyspnea and less need for mechanical ventilation compared to the cases with COVID-19 only. On the other hand, COVID-19/TB patients had higher levels of C-reactive protein and lower hemoglobin levels, the latter variable was independently associated with COVID-19/TB. Among the clinical differences presented among COVID-19/TB co-infected patients, despite the association with HIV and lower clinical repercussions, only lower hemoglobin levels were associated with COVID-19/TB. Currently COVID19 COVID 19 COVID-1 (TB worldwide synergy presentation morbidity explored Thus epidemiological coinfection co casecontrol case control 2 laboratoryconfirmed confirmed COVID19/TB COVID19TB COVIDTB 19/TB coinfected infected group group. . city State Brazil 202 2022 p005 p 0 05 p≤0.05 coinfection, infection, controlgroup, controlgroup group, control-group outcome hand Creactive C reactive COVID19/TB. 19/TB. repercussions COVID1 1 COVID- 19TB 20 p00 p≤0.0 p0 p≤0. p≤0 p≤

https://doi.org/10.1590/s1678-9946202466065

CARBONIZATION GASES AS AN ENERGY SOURCE FOR Eucalyptus LOGS DRYING OF DIFFERENT DIAMETER CLASSES IN METALLIC DRYER
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Carneiro, Angélica de Cássia Oliveira

; Cardoso, Marco Tulio

; Zanuncio, Antonio José Vinha

; Pereira, Emanuele Graciosa

; Carvalho, Ana Marcia Macedo Ladeira

; Martins, Marcio Arêdes

; Guimarães, Dandara Paula da Silva

; Evangelista, Evanderson Luis Capelete

; Castro, Vinícius Resende de

; Carvalho, Amélia Guimarães

; Araujo, Solange de Oliveira

Revista Árvore

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2024, Volume 48 elocation e4830

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT The wood carbonization with high moisture content reduces the yield, prolongs the carbonization time and results in charcoal with low mechanical strength. Considering this, the reuse of carbonization gases as a source of thermal energy becomes a potential alternative for reducing moisture content quickly and feasibly. The objective of this study was to evaluate the artificial drying of logs using gases from the carbonization system of a furnace and a drying chamber. The drying evaluation was conducted in duplicate using a 35 m³ galvanized metal square dryer and a furnace with a useful volume capacity of 16.8 m³. The average gas intake temperature for drying was 150°C. The eucalyptus logs were divided into three diameter classes (8-14 cm; 14-22 cm; 8-22 cm). The electricity consumption of the dryer was approximately 49.4 kW per ton of wood (dry mass). The highest thermal efficiency was achieved in the drying of 814 cm diameter class logs. The utilization of carbonization gases proved to be effective in reducing wood moisture in all diameter classes, showing potential for large scale utilization. yield strength feasibly chamber 3 m 168 16 8 16. 150C C 150 150°C 14 (8-1 1422 22 14-2 822 8-2 cm. . cm) 494 49 4 49. dry mass. mass mass) 81 1 15 (8- 142 2 14- 82 8- (8 (

RESUMO A carbonização da madeira com alto teor de umidade reduz o rendimento, prolonga o tempo de carbonização e resulta em carvão vegetal com baixa resistência mecânica. Diante disso, o reaproveitamento dos gases da carbonização como fonte de energia térmica se torna uma alternativa em potencial para redução do teor de umidade de forma rápida e viável. O objetivo deste estudo foi avaliar a secagem artificial de toras utilizando gases do sistema de carbonização de um forno e uma câmara de secagem. A avaliação da secagem foi realizada em duplicata utilizando um secador quadrado de metal galvanizado de 35 m³ e um forno com capacidade volumétrica útil de 16,8 m³. A temperatura média de admissão dos gases para a secagem foi de 150 °C. As toras de eucalipto foram divididas em três classes de diâmetro (8-14 cm; 14-22 cm e; 8-22 cm). O consumo de eletricidade do secador foi aproximadamente de 49,4 kW por tonelada de madeira (massa seca). A maior eficiência térmica foi alcançada na secagem de toras da classe de diâmetro de 8-14 cm. A utilização de gases de carbonização se mostrou eficaz na redução da umidade da madeira nas três classes de diâmetro, mostrando potencial para utilização em larga escala. rendimento mecânica disso viável 3 m 168 16 8 16, 15 C °C 814 14 (8-1 1422 22 14-2 822 8-2 . cm) 494 49 4 49, massa seca. seca seca) 8-1 escala 1 81 (8- 142 2 14- 82 8- (8 (

https://doi.org/10.53661/18069088202448263784

Segurança alimentar: reflexões sobre um problema complexo
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DOMENE, SEMÍRAMIS MARTINS ÁLVARES

; AGOSTINI, KAYNA

; ALMEIDA, GABRIEL NATALE PINTO DE

; CAMARGO, RAFAELLA GUIMARÃES MORAES

; CARVALHO, ALINE MARTINS DE

; CORRÊA, FERNANDO ELIAS

; DELBEM, ALEXANDRE CLÁUDIO BOTAZZO

; DOMINGOS, SARA STEFANI

; DRUCKER, DEBORA PIGNATARI

; MARCHIONI, DIRCE MARIA LOBO

; MARTINS, ISABELA PRADO

; MONTEDO, UIARA BANDINELI

; RIBEIRO, EVANDRO MARCOS SAIDEL

; SANTIAGO, RAQUEL DE ANDRADE CARDOSO

; SILVA, ROBERTO FRAY DA

; SOARES, FILIPI MIRANDA

; STELUTI, JOSIANE

; SARAIVA, ANTÓNIO MAURO

Estudos Avançados

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dec 2023, Volume 37 N. 109 Pages 181 - 206

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Overcoming malnutrition in all its forms, which is also manifested in the obesity epidemic, is one of the priorities of the 2030 Agenda and the Sustainable Development Goals. This article presents reflections on food insecurity in Brazil, based on topics such as population growth, climate change, biodiversity and traditional and regenerative food systems; it also addresses the role of social initiatives to guarantee the Human Right to Adequate Food. The Nutrition and Poverty Research Group, Planetary Health - Brazil Group, and the Center for Artificial Intelligence (C4AI) - AgriBio Axis, assume that the organized and systemic resumption of the initiatives mentioned out in this position paper can contribute to the articulation between research, public policies and services, to combat all forms of malnutrition, as a complex and priority problem to ensure social welfare.

RESUMO O combate à má alimentação em todas as suas formas, que também se expressa na epidemia da obesidade, é uma das prioridades da Agenda 2030 e dos Objetivos de Desenvolvimento Sustentável. Este artigo traz elementos sobre insegurança alimentar no Brasil, a partir de temas relativos ao crescimento populacional, mudanças climáticas, biodiversidade e sistemas alimentares tradicionais e regenerativos; trata também do papel dos movimentos sociais para a garantia do Direito Humano à Alimentação Adequada. O Grupo de Pesquisa em Nutrição e Pobreza, o Saúde Planetária Brasil, e o Centro de Inteligência Artificial (C4AI) - Eixo AgriBio, entendem que a retomada organizada e sistêmica das frentes apontadas neste artigo de posicionamento, pode constituir um caminho para a articulação entre pesquisa, serviço e políticas públicas na direção do combate à fome e às demais manifestações da má alimentação, enquanto problema complexo prioritário para a garantia do bem-estar social.

https://doi.org/10.1590/s0103-4014.2023.37109.012

Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil
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LOUREDO, Brendo Vinicius Rodrigues

; CURADO, Maria Paula

; PENAFORT, Paulo Victor Mendes

; DE ARRUDA, José Alcides Almeida

; ABREU, Lucas Guimarães

; MESQUITA, Ricardo Alves

; PINTO-JÚNIOR, Décio dos Santos

; ABRAHÃO, Aline Corrêa

; ANDRADE, Bruno Augusto Benevenuto de

; AGOSTINI, Michelle

; MORAES, Renata Mendonça

; ANBINDER, Ana Lia

; DOURADO, Pedro Henrique Silva

; SANTOS, Teresa Cristina Ribeiro Bartholomeu dos

; PIRES, Fábio Ramoa

; BORDIGNON, Natalia Cristina Trentin

; GONDAK, Rogério Oliveira

; DE OLIVEIRA, Marcia Gaiger

; CARRARD, Vinicius Coelho

; MARTINS, Manoela Domingues

; SOUSA-NETO, Sebastião Silvério

; ARANTES, Diego Antônio Costa

; MENDONÇA, Elismauro Francisco

; CIESLAK-SANCHES, Silvia Roberta

; ANTUNES, Daniella Moraes

; AMARAL-SILVA, Gleyson Kleber do

; MANIERI, Patricia Rubia

; RAMALHO, Luciana Maria Pedreira

; DOS SANTOS, Jean Nunes

; LEONEL, Augusto César Leal da Silva

; PEREZ, Danyel Elias da Cruz

; VERHEUL, Hannah Carmem Carlos Ribeiro Silva

; BARROSO, Keila Martha Amorim

; RODRIGUES, Flávia Luiza Santos

; GONZAGA, Amanda Katarinny Goes

; FERNANDES, Romana Renery

; DE SOUZA, Lélia Batista

; SOUZA, Lucas Lacerda de

; PONTES, Flávia Sirotheau Corrêa

; PONTES, Hélder Antônio Rebelo

; SILVA, Caroline Alfaia

; CÂMARA, Jeconias

; LIBÓRIO-KIMURA, Tatiana Nayara

; SANTOS-SILVA, Alan Roger

; LOPES, Márcio Ajudarte

; ALMEIDA, Oslei Paes de

; ROMAÑACH, Mário José

; VARGAS, Pablo Agustin

Brazilian Oral Research

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2023, Volume 37 elocation e126

Abstract: En | Text: En | PDF: En

Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients’ histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil’s Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0126

O Treinamento Físico Resistido Atenua as Disfunções Ventriculares Esquerdas em Modelo de Hipertensão Arterial Pulmonar
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Soares, Leôncio Lopes

; Leite, Luciano Bernardes

; Ervilha, Luiz Otávio Guimarães

; Silva, Bruna Aparecida Fonseca da

; Freitas, Maíra Oliveira de

; Portes, Alexandre Martins Oliveira

; Rezende, Leonardo Mateus Teixeira

; Drummond, Filipe Rios

; Carneiro-Júnior, Miguel Araújo

; Neves, Mariana Machado

; Reis, Emily Correna Carlo

; Natali, Antônio José

Arquivos Brasileiros de Cardiologia

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oct 2022, Volume 119 N. 4 Pages 574 - 584

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Fundamento A hipertrofia e a dilatação do ventrículo direito observadas na hipertensão arterial pulmonar (HAP) prejudicam a dinâmica do ventrículo esquerdo (VE) achatando o septo interventricular. Objetivo Investigar se o treinamento físico resistido (TFR) de intensidade baixa a moderada é benéfico para funções contráteis do VE e de cardiomiócitos em ratos durante o desenvolvimento de HAP induzida por monocrotalina (MCT). Métodos Foram usados ratos Wistar machos (Peso corporal: ~ 200 g). Para avaliar o tempo até o possível surgimento de insuficiência cardíaca (ou seja, ponto de desfecho), os ratos foram divididos em dois grupos, hipertensão com sedentarismo até a insuficiência (HSI, n=6) e hipertensão com treinamento até a insuficiência (HTI, n=6). Para testar os efeitos do TFR, os ratos foram divididos entre grupos de controle sedentários (CS, n=7), hipertensão com sedentarismo (HS, n=7) e hipertensão com treinamento (HT, n=7). A HAP foi induzida por duas injeções de MCT (20 mg/kg, com um intervalo de 7 dias). Os grupos com treinamento foram submetidos a um protocolo de TFR (subir escadas; 55-65% da máxima carga carregada), 5 dias por semana. A significância estatística foi definida em p <0,05. Resultados O TFR prolongou o ponto de desfecho (~25%), melhorou a tolerância ao esforço físico (~55%) e atenuou as disfunções de contratilidade de VE e de cardiomiócitos promovidas pela MCT preservando a fração de ejeção e o encurtamento fracional, a amplitude do encurtamento, e as velocidades de contração e relaxamento nos cardiomiócitos. O TFR também preveniu os aumentos de fibrose e colágeno tipo I no ventrículo esquerdo causados pela MCT, além de manter as dimensões de miócitos e colágeno tipo III reduzidas por MCT. Conclusão O TFR de intensidade baixa a moderada é benéfico para funções contráteis de VE e cardiomiócitos em ratos durante o desenvolvimento de HAP induzida por MCT.

Abstract Background The right ventricular hypertrophy and dilation observed in pulmonary artery hypertension (PAH) damages the left ventricle (LV) dynamics by flattening the interventricular septum. Objective To investigate whether low- to moderate-intensity resistance exercise training (RT) is beneficial to LV and cardiomyocyte contractile functions in rats during the development of monocrotaline (MCT)-induced PAH. Methods Male Wistar rats (Body weight: ~ 200 g) were used. To assess the time to potential heart failure onset (i.e., end point), rats were divided into sedentary hypertension until failure (SHF, n=6) and exercise hypertension until failure (EHF, n=6) groups. To test RT effects, rats were divided into sedentary control (SC, n = 7), sedentary hypertension (SH, n=7), and exercise hypertension (EH, n=7) groups. PAH was induced by two MCT injections (20 mg/kg, with 7 days interval). Exercise groups were submitted to an RT protocol (Ladder climbing; 55-65% of carrying maximal load), 5 times/week. Statistical significance was assumed at P < 0.05. Results RT prolonged the end point (~25 %), enhanced the physical effort tolerance (~ 55%), and mitigated the LV and cardiomyocyte contractility dysfunctions promoted by MCT by preserving the ejection fraction and fractional shortening, the amplitude of shortening, and the velocities of contraction and relaxation in cardiomyocytes. RT also prevented increases in left ventricle fibrosis and type I collagen caused by MCT, and maintained the type III collagen and myocyte dimensions reduced by MCT. Conclusion Low- to moderate-intensity RT benefits LV and cardiomyocyte contractile functions in rats during the development of MCT-induced PAH.

https://doi.org/10.36660/abc.20210681

Cutaneous adverse events to systemic antineoplastic therapies: a retrospective study in a public oncologic hospital
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Ceglio, William Queiroz Guimarães Wiegandt

; Rebeis, Marina Mattos

; Santana, Marcela Ferreira

; Miyashiro, Denis

; Cury-Martins, Jade

; Sanches, José Antônio

Anais Brasileiros de Dermatologia

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feb 2022, Volume 97 N. 1 Pages 14 - 21

Abstract: En | Text: En | PDF: En

Abstract Background: Mucocutaneous adverse events are common during anticancer treatment, with variable consequences for the patient and their therapeutic regimen. Objective: To evaluate the most common adverse events, as well as the drugs associated with their appearance and the consequences for cancer treatment. Methods: A retrospective study was carried out through the analysis of patients treated at the Clinical Dermatology Unit of a public oncologic hospital. Results: A total of 138 patients with 200 adverse events were evaluated. The most commonly identified adverse events were nail and periungual changes (20%), papulopustular eruptions (13%), acneiform eruptions (12%), hand-foot syndrome (6.5%), hand-foot skin reaction (6%), and xerosis (6%). The most frequently associated antineoplastic treatment groups were classical chemotherapy (46.2%), target therapy (32.3%), and other non-antineoplastic drugs used in neoplasia protocols (16.5%). Of the total number of patients, 17.4% had their treatment suspended or changed due to a dermatological adverse event. Study limitations: Retrospective study and analysis of patients who were referred for specialized dermatological examination only, not allowing the assessment of the actual incidence of adverse events. Conclusion: A wide variety of dermatological manifestations are secondary to antineoplastic treatment with several different drugs resulting, not rarely, in the interruption or modification of therapeutic regimens.

https://doi.org/10.1016/j.abd.2021.05.007

Structural characteristics of oral health services in Brazilian Primary Health Care
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SCALZO, Maria Tereza Abreu

; MATTA-MACHADO, Antônio Thomaz Gonzaga

; ABREU, Mauro Henrique Nogueira Guimarães

; MARTINS, Renata Castro

Brazilian Oral Research

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2021, Volume 35 elocation e023

Abstract: En | Text: En | PDF: En

Abstract This study aimed to describe the structure of oral health services in primary health care in Brazil with centers participating in the second cycle of the ‘National Program for Improving Access and Quality of Primary Care’ (PMAQ-AB), the largest health service evaluation program ever instituted in the country. This cross-sectional study evaluated 16,202 oral health services, regarding 22 pieces of dental equipment and 25 dental supplies. The presence of each piece of equipment/dental supply generated a score for services. The sum of these scores was compared among different regions in Brazil. Quantitative data were described by quartiles and categorical data by frequencies, using the SPSS, version 25. Most of the evaluated centers presented adequate equipment in good using conditions and sufficient dental supplies for primary oral health care. Data also showed a lack of some equipment, such as X-rays, bicarbonate jet, and ultrasound devices, while for dental supplies, a lack of amalgam (capsule and manual preparation), anesthesia without vasoconstrictors, and intracanal medication was found. The services presented a median of 14 pieces of equipment and 22 dental supplies. Of the Brazilian regions, the South presented the highest median, while the North and Northeast regions presented the lowest one. The oral health services presented dental offices with good availability of equipment and dental supplies to perform clinical activities. However, differences in the structure of services among the Brazilian regions was still observed.

https://doi.org/10.1590/1807-3107bor-2021.vol35.0023 482 downloads

Selection of carioca common bean lines with slow darkening
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Pereira, Helton Santos

; Mendonça, Fabiana Rocha

; Rodrigues, Ludivina Lima

; Melo, Leonardo Cunha

; Melo, Patrícia Guimarães Santos

; Faria, Luís Cláudio de

; Costa, Antônio Félix da

; Carvalho, Hélio Wilson Lemos de

; Pereira Filho, Israel Alexandre

; Almeida, Válter Martins de

Pesquisa Agropecuária Brasileira

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2021, Volume 56 elocation e02471

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste trabalho foi avaliar a interação entre genótipos e ambientes para o escurecimento de grãos de feijão carioca (Phaseolus vulgaris), a fim de selecionar linhagens que associem escurecimento lento, arquitetura ereta, tolerância ao acamamento, e maior produtividade e peso de 100 grãos, com boa adaptabilidade e estabilidade para esses caracteres. Foram avaliadas 44 linhagens pré-selecionadas, oriundas de cruzamentos entre uma cultivar com escurecimento lento e arquitetura prostrada e quatro cultivares com escurecimento normal e arquitetura ereta, em experimentos de campo conduzidos em 15 ambientes (combinações de locais, épocas de semeadura e anos). Ao se considerar as médias, a adaptabilidade e a estabilidade para cada caráter isoladamente, a maior parte das linhagens apresentou desempenho satisfatório: 75% para escurecimento lento, 48% para alta produtividade, 59% para arquitetura ereta, 84% para tolerância ao acamamento e 68% para peso de 100 grãos. Os efeitos dos ambientes e da interação entre genótipos e ambientes são importantes para os cinco caracteres estudados. As linhagens CNFC 16754 e CNFC 16820 apresentam escurecimento lento dos grãos, alta produtividade e peso de 100 grãos, plantas mais eretas e alta tolerância ao acamamento, além de alta adaptabilidade e estabilidade para esses caracteres, o que mostra o seu potencial para recomendação como novas cultivares e confirma que é possível reunir fenótipos desejáveis para os cinco caracteres avaliados.

Abstract The objective of this work was to evaluate the interaction between genotypes and environment for seed-coat darkening of common bean (Phaseolus vulgaris) seeds, in order to select lines that combine slow darkening, upright plants, resistance to lodging, and higher yield and 100-grain weight, with good adaptability and stability for these traits. Forty four pre-selected lines, originating from crosses between one cultivar with slow darkening and prostrate plants and four cultivars with normal darkening and upright plants, were evaluated in field trials conducted in 15 environments (combinations of locations, crop seasons, and years). Considering the mean values, adaptability, and stability for each isolated trait, most of the lines presented satisfactory performance: 75% for slow darkening, 48% for high yield, 59% for upright plants, 84% for resistance to lodging, and 68% for 100-grain weight. The effects of environments and of the genotype by environment interaction are important for the five studied traits. The CNFC 16754 and CNFC 16820 lines present slow seed-coat darkening, high yield and 100-grain weight, more upright plant architecture, and greater resistance to lodging, besides high adaptability and stability for these traits, which shows their potential for recommendation as new cultivars and confirms that it is possible to join desirable phenotypes for the five traits evaluated.

https://doi.org/10.1590/s1678-3921.pab2021.v56.02471

10.

Contextual and individual factors associated with dental pain in adolescents from Southeastern Brazil
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MACEDO, Thaís de Faria Fonseca

; ABREU, Mauro Henrique Nogueira Guimarães de

; MARTINS, Renata de Castro

; MATTA-MACHADO, Antônio Thomaz Gonzaga da

; PINTO, Rafaela da Silveira

; CASTILHO, Lia Silva de

; VARGAS-FERREIRA, Fabiana

Brazilian Oral Research

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2021, Volume 35 elocation e111

Abstract: En | Text: En | PDF: En

Abstract The aim of this study was to assess the factors associated with dental pain in adolescents from the state of Minas Gerais, Brazil. Individual data on adolescents aged 15 to 19 years were collected from the SB Minas survey secondary database. Dental pain over the past 6 months, assessed by a questionnaire, was used as the dependent variable. Sex, income, skin color, prevalence of untreated dental caries, periodontal health, dental treatment needs, and time of last dental appointment were analyzed as individual covariates. Allocation factor, Human Development Index (HDI), Gini coefficient, illiteracy rate, unemployment, 50% and 25% of the Brazilian monthly minimum wage, primary healthcare coverage, oral health team coverage, access to individual healthcare, and supervised toothbrushing average rate were the analyzed contextual variables. A multilevel analysis was conducted for the individual and contextual variables. Statistical analyses used hierarchical linear and nonlinear modeling to infer an association between the different levels. Male adolescents had a lower prevalence of dental pain (OR = 0.53; 95%CI = 0.37–0.75). There was an association between dental pain and low income (OR = 1.58; 95%CI = 1.07–2.33), prevalence of untreated dental caries (OR = 1.25; 95%CI = 1.11–1.40), periodontal health (OR = 1.80; 95%CI = 1.04–3.09), and dental treatment needs (OR = 6.93; 95%CI = 3.96–12.14). Sociodemographic and clinical factors at the individual level were associated with the outcome but not with contextual variables. These findings reinforce the need to address these factors for effective community health actions.

https://doi.org/10.1590/1807-3107bor-2021.vol35.0111 2 downloads

11.

Oral Health-Related Quality Of Life of Pre-School Children: Review and Perspectives for New Instruments
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Perazzo, Matheus França

; Martins-Júnior, Paulo Antônio

; Abreu, Lucas Guimarães

; Mattos, Flávio Freitas

; Pordeus, Isabela Almeida

; Paiva, Saul Martins

Brazilian Dental Journal

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nov 2020, Volume 31 N. 6 Pages 568 - 581

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Qualidade de Vida Relacionada à Saúde Bucal (QVRSB) é um conceito que extrapola uma percepção exclusivamente clínica ao incluir questões funcionais, sociais, emocionais e ambientais. A avaliação da QVRSB representa uma abordagem holística para a pesquisa e prática clínica. O impacto negativo das condições bucais na QVRSB durante a infância pode refletir no desenvolvimento saudável, especialmente em um estágio da vida marcado pela maturação social e cognitiva. Instrumentos vêm sendo desenvolvidos e adaptados transculturalmente para avaliar o impacto das condições bucais na QVRSB de pré-escolares e seus familiares. Algumas características distinguem esses instrumentos e influenciam na seleção, tais como: autorrelato ou relato proxy; condição genérica ou específica; formas longas ou curtas, mais ou menos estabelecidos na literatura. Além disso, a base teórica, a avaliação do construto e a disponibilidade do instrumento também devem ser consideradas. A diversidade de instrumentos indica a evolução dos estudos em QVRSB, mas ainda há questões metodológicas que precisam ser avançadas em futuros desenvolvimentos ou adaptações desses instrumentos, seguindo as atuais evidências psicométricas. O presente estudo objetiva descrever as diferentes abordagens para avaliar a QVRSB de pré-escolares e discutir as perspectivas para futuros instrumentos.

Abstract This study aimed to describe different approaches for the evaluation of the Oral health-related quality of life (OHRQoL) of preschool children and to discuss perspectives for future instruments. The OHRQoL is a concept that surpasses an exclusively clinical perception and includes functional, social, emotional, and environmental issues. The measure of OHRQoL represents a holistic approach for researchers and clinicians extending their visions beyond the mouth and understanding the entire context of the patient. Negative impacts of oral conditions on OHRQoL in childhood can reflect on health development, especially in a life stage marked by social and cognitive maturation. Instruments have been developed and cross-culturally adapted to evaluate the impact of oral conditions on the OHRQoL of preschool children and their families. Some features distinguish these instruments and influence their selection, such as: self- or proxy-report; generic- or specific-condition; long- or short-form, and less or more established used in literature. Moreover, theoretical framework, construct validation and availability should also be considered. Nine OHRQoL instruments for preschool children were included in the present literature review. They were created between 2003 and 2017 by developed countries in most cases. The shorter instrument has five items, and the larger has 31 items. Most of them are proxy-reported, generic-condition, and have been relatively well established in the literature. The diversity of instruments indicates the evolution of OHRQoL studies, but there are methodological issues still in need to be improved in future developments or cross-cultural adaptations, according to current psychometric evidence.

https://doi.org/10.1590/0103-6440202003871 1506 downloads

12.

Increased platelet distribution width and reduced IL-2 and IL-12 are associated with thrombocytopenia in Plasmodium vivax malaria
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Costa, Allyson Guimarães

; Chaves, Yury Oliveira Teixeira-Carvalho, Andréa Ramasawmy, Rajendranath Antonelli, Lis Ribeiro Valle Barbosa, Lucas Balieiro, Antonio Monteiro, Wuelton Marcelo Mourão, Maria Paula Lacerda, Marcus Vinicius Guimarães Martins-Filho, Olindo Assis Costa, Fabio Trindade Maranhão Malheiro, Adriana Nogueira, Paulo Afonso

Memórias do Instituto Oswaldo Cruz

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2020, Volume 115 elocation e200080

Abstract: En | Text: En | PDF: En

BACKGROUND Thrombocytopenia in malaria involves platelet destruction and consumption; however, the cellular response underlying this phenomenon has still not been elucidated. OBJECTIVE To find associations between platelet indices and unbalanced Th1/Th2/Th17 cytokines as a response to thrombocytopenia in Plasmodium vivax infected (Pv-MAL) patients. METHODS Platelet counts and quantification of Th1/Th2/Th17 cytokine levels were compared in 77 patients with uncomplicated P. vivax malaria and 37 healthy donors from the same area (endemic control group - ENCG). FINDINGS Thrombocytopenia was the main manifestation in 55 patients, but was not associated with parasitaemia. The Pv-MAL patients showed increases in the mean platelet volume (MPV), which may be consistent with larger or megaplatelets. Contrary to the findings regarding the endemic control group, MPV and platelet distribution width (PDW) did not show an inverse correlation, due the increase in the heterogeneity of platelet width. In addition, the Pv-MAL patients presented increased IL-1β and reduced IL-12p70 and IL-2 serum concentrations. Furthermore, the reduction of these cytokines was associated with PDW values. MAIN CONCLUSIONS Our data demonstrate that an increase in MPV and the association between reductions of IL-2 and IL-12 and PDW values may be an immune response to thrombocytopenia in uncomplicated P. vivax malaria.

https://doi.org/10.1590/0074-02760200080 790 downloads

13.

Homeopathy and Periodontal Treatment in Type II Diabetic Patients: a 1-Year Randomized Clinical Trial
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Mourão, Leila

; Carillo Jr, Romeu Linares, Sabrina Martins Canabarro, Antonio Fischer, Ricardo Guimarães

Brazilian Dental Journal

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mar 2019, Volume 30 N. 2 Pages 139 - 145

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Periodontite crônica (CP) e Diabetes mellitus tipo 2 (DMII) são doenças crônicas normalmente tratadas por práticas convencionais. Por outro lado, a homeopatia pode colaborar no tratamento de diferentes doenças. O objetivo do presente estudo foi avaliar os efeito da homeopatia como adjunto a terapia periodontal não cirúrgica (NSPT) em indivíduos com CP e DMII. Oitenta indivíduos com CP e DMII de ambos os sexos com idade entre 32 e 70 anos, participaram desse estudo clínico randomizado, placebo controlado, duplo cego. Os pacientes foram divididos em 2 grupos: grupo controle (CG) e grupo teste (TG), e ambos receberam NSPT. TG também recebeu terapia homeopática, incluindo Berberis, Mercurius solubilis/Belladonna/Hepar sulphur and Pyrogenium, enquanto o CG recebeu placebo. Exames clínicos e laboratoriais foram avaliados no baseline e 1, 6 e 12 meses após o tratamento. Ambos grupos mostraram melhoras significantes através do estudo para a maioria dos parâmetros avaliados. TG apresentou um ganho significativo nos níveis clínicos de inserção aos 1 e 12 meses, quando comparado ao grupo controle. Valores médios de glicemia e hemoglobina glicada reduziram significativamente em ambos grupos aos 6 e 12 meses. Entretanto, houve uma redução adicional desses parâmetros no TG, quando comparado ao CG. Concluindo, homeopatia como suplemento a NSPT pode promover as condições de saúde, incluindo o controle glicêmico, em pacientes com DMII e CP.

Abstract Chronic periodontitis (CP) and Diabetes mellitus type 2 (DMII) are chronic diseases usually treated by conventional practices. On the other hand, homeopathy can help to treat many different diseases. The aim of this study was to evaluate the effects of homeopathy (H) as an adjunct for non-surgical periodontal therapy (NSPT) in individuals with DMII and CP. Eighty individuals with CP and DM II, of both sexes and aged between 32 and 70 years, participated in this randomized, double-blind, placebo-controlled study. They were divided into two groups: control group (CG) and the test group (TG), and both groups received the NSPT. TG also received homeopathic therapy, including Berberis, Mercurius solubilis/Belladonna/Hepar sulphur and Pyrogenium, while CG received placebo. Clinical and laboratorial examinations were evaluated at baseline and after 1, 6 and 12 months of treatment. Both groups showed significant improvement throughout the study, for most of the parameters studied, but TG presented significative gain of CAL at 1 and 12 months compared to CG. Mean glucose and glycated hemoglobin significantly decreased in both groups after 6 and 12 months. However, there was a significantly further reduction of these parameters in TG, as compared to CG. In conclusion, homeopathy as supplement of NSPT may further improve health condition, including glycemic control, in DMII patients with CP.

https://doi.org/10.1590/0103-6440201902124 4963 downloads

14.

Eugenia Klotzschiana O. Berg Fruits as New Sources of Nutrients: Determination of their Bioactive Compounds, Antioxidant Activity and Chemical Composition
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Carneiro, Nárgella Silva

; Alves, Cássia Cristina Fernandes

; Cagnin, Caroline

; Belisario, Celso Martins

; Silva, Marco Antônio Pereira da

; Miranda, Mayker Lazaro Dantas

; Oliveira Filho, Josemar Gonçalves de

; Alves, José Milton

; Pereira, Paulo Sérgio

; Silva, Fabiano Guimarães

; Egea, Mariana Buranelo

Brazilian Archives of Biology and Technology

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2019, Volume 62 elocation e19170562

Abstract: En | Text: En | PDF: En

Abstract: The Cerrado is one of the world's biodiversity hotspots and Brazil’s second largest biome. Many native species of the Brazilian Cerrado provide fruits that have unique sensory characteristics and high nutritional value. This study aimed at characterizing the pulp of Eugenia klotzschiana O. Berg, concerning its proximal composition, bioactive compound content and antioxidant activity. The pulp under study had high moisture (89.47 g kg-1) and caloric (96.07 kcal kg-1) values whereas its contents of protein (0.59 g kg-1) and lipids (2.35 g kg-1) were low. The cerrado pear pulp also had high iron content (16.5 mg kg -1) and dietary fiber (6.45 g kg-1), besides 0.034-0,055 mg kg-1 carotenoids, 8.66 mg kg-1 ascorbic acid and 0.66 mg kg-1 total chlorophyll. Total phenolic compounds (333.41-566.33 mg EAG kg-1) and flavonoids (225-50 mg EQ kg-1) were found by extraction methods named Method 1 (water) and Method 2 (acetone+methanol), respectively. Thus, the cerrado pear can be an alternative to improving nutrient intake and to providing sustainable use of the native flora in the Cerrado.

https://doi.org/10.1590/1678-4324-2019170562 1131 downloads

15.

Toxoplasma gondii infection and chronic schizophrenia: is there any association?
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Campos-Carli, Salvina Maria de Vieira, Érica Leandro Marciano Rocha, Natalia Pessoa Oliveira, Keliane de Guimarães, Fernanda Carneiro Barbosa, Izabela Guimarães Barros, João Luís Vieira Monteiro de Okusaga, Olaoluwa Martins-Filho, Olindo Assis Salgado, João Vinícius Teixeira, Antônio Lúcio

Archives of Clinical Psychiatry (São Paulo)

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dec 2017, Volume 44 N. 6 Pages 145 - 148

Abstract: En | Text: En | PDF: En

ABSTRACT Background: Toxoplasma gondii (T. gondii) infection has been identified as a risk factor for schizophrenia. Objectives: Herein, we sought to evaluate the association between T. gondii infection and clinical symptoms and quality of life in patients with schizophrenia. Methods: We conducted a cross-sectional study with 48 patients with chronic schizophrenia and 40 controls. Peripheral blood was drawn, and IgM and IgG anti-T. gondii antibodies were evaluated by Enzyme-Linked Immunosorbent Assay (ELISA). Depressive, positive and negative symptoms were assessed, respectively, by the Calgary Depression Scale (CDS) and the Positive and Negative Syndrome Scale (PANSS). Cognitive performance was assessed in patients by the Brazilian version of the Schizophrenia Cognition Rating Scale (SCoRS-BR). Quality of life was assessed by the Brazilian version of the Quality of Life in Schizophrenia scale (QLS-BR). Results: The prevalence and titers of T. gondii IgM and IgG antibodies did not differ between patients and controls. The positive serology for T. gondii IgG antibodies was not associated with illness symptoms, cognitive performance, depressive symptoms or quality of life. Discussion: Our findings suggest that toxoplasmosis infection is not associated with severity of symptoms, quality of life, cognitive or depressive symptoms in schizophrenia patients.

https://doi.org/10.1590/0101-60830000000140 2009 downloads

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