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Lantana caatingensis Moldenke (Verbenaceae) is an endemic plant from northeastern Brazil. However, its chemical composition is almost unknown. This study aimed to characterize the chemical compounds found in L. caatingensis and investigate the antileishmanial potential of its hydroalcoholic extract and polar fractions. Compounds present in the hydroalcoholic extract obtained from L. caatingensis leaves and its polar fractions (ethyl acetate and methanolic) were analyzed by liquid chromatography with a photodiode-array detector coupled to electrospray ionization quadrupole time-of-flight mass spectrometry. An antileishmanial assay was performed in a 96-well plate against Leishmania major promastigotes using resazurin on a plate spectrophotometer and the results were expressed as percentage of growth inhibition. Nine compounds were determined in the investigated extract and fractions, classified as flavonoids, flavonoid C-glycosides and phenylethanoid glycosides. The antileishmanial activity revealed that the hydroalcoholic extract and the ethyl acetate fraction were active against L. major promastigotes with inhibitory concentration of 71.78 and 26.86 µg mL-1, respectively, while the methanolic fraction was inactive (478.40 µg mL-1). This is the first report on the chemical composition and antileishmanial activity of L. caatingensis extracts. These results contribute to further knowledge of species belonging to the Lantana genus. Verbenaceae (Verbenaceae Brazil However unknown L photodiodearray photodiode array timeofflight time flight spectrometry 96well well 96 inhibition flavonoids Cglycosides C glycosides 7178 71 78 71.7 2686 26 86 26.8 mL1, mL1 mL 1, 1 mL-1 respectively 478.40 47840 478 40 (478.4 mL1. . mL-1) extracts genus 9 717 7 71. 268 2 8 26. mL- 478.4 4784 47 4 (478. 478. (478 (47 (4 (

https://doi.org/10.21577/0103-5053.20240113

ALFRED SCHAEFFER E SUAS CONTRIBUIÇÕES PARA A QUÍMICA
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Silva, Rodrigo Régis C.

; Marques, Rita de Cássia

; Filgueiras, Carlos A. L.

Química Nova

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2025, Volume 48 N. 1 elocation e-20250012

Abstract: Pt | Text: Pt | PDF: Pt

Alfred Schaeffer (1879-1957) was a German chemist who arrived in Minas Gerais in 1911 hired by the state government to organize the state health service in its newly established capital. He directed the Laboratory of Chemical Analysis of the State, and his analytical methods in dairy and mineral waters became a reference in Brazil. He also became professor of Chemistry at the new Faculty of Medicine of Belo Horizonte and founded the Chemistry Institute of the Engineering School in that city, influencing several students who became important names in Brazilian science. In addition, he was responsible for the assembly and technical coordination of pioneering industries in the dairy and wood distillation sector in the city of Santos Dumont. Later he assumed the post of technical director of Merck, also in Minas Gerais. Moving to Rio de Janeiro, he assumed a chair at the Technical School, working in teaching and research, and remained active even after retiring, publishing in important scientific journals. 18791957 1879 1957 (1879-1957 191 capital State Brazil science addition Dumont Merck Janeiro research retiring journals 1879195 187 195 (1879-195 19 187919 18 (1879-19 1 18791 (1879-1 (1879- (1879 (187 (18 (1 (

https://doi.org/10.21577/0100-4042.20250012

Hospitalization and mortality rates of malignant prostatic neoplasms in Brazil: A cross-sectional study from 2008 to 2018 Brazil crosssectional cross sectional 200 201 20 2
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Justo, Alberto Fernando Oliveira

; Collaço, Rita de Cássia

; Soares, Anna Ligia Oenning

; Caloi, Caroline Marques

; Estancial, Camila Stefani

; Lemos, Guilherme

; Silva, Fabio Henrique da

; Alexandre, Eduardo Costa

; Calmasini, Fabiano Beraldi

Brazilian Journal of Pharmaceutical Sciences

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2024, Volume 60 elocation e23366

Abstract: En | Text: En | PDF: En

Abstract Prostate cancer (PCa) is a highly prevalent condition among men worldwide, resulting in reduced quality of life and increased costs to health systems due to hospitalization and death. This study aimed to explore and understand the evolution of PCa in Brazil from 2008 to 2018. Data were obtained from the National Health System Department of Informatics (DATASUS) using code C61 for malignant prostatic neoplasms. We presented the hospitalization and mortality rates in a temporal-, regional- and age-dependent manner. From 2008 to 2018, a year-dependent increase in hospital admissions due to PCa was reported in Brazil, in which the Southeast region showed the highest prevalence. Men aged ≥80 and those 70-79 years old had similar hospitalization rates, followed by men aged 60-69, 50-59, 40-49 and 30-39 years old. Similarly, an increase in deaths due to PCa was reported during this period, with the highest rates seen in the Southeast. Men aged ≥80 years had higher mortality rates, followed by those aged 70-79, 60-69, 50-59, 40-49 and 30-39 years old. The results obtained indicate an age- and region-dependent increase in PCa morbidity and mortality in Brazil overtime and may contribute to the ongoing discussion on the role and future perspective of the health care system in Brazil. (PCa worldwide death 200 2018 DATASUS (DATASUS C C6 neoplasms temporal, temporal , temporal- regional agedependent age dependent manner yeardependent year prevalence 80 ≥8 7079 70 79 70-7 6069, 6069 60 69, 69 60-69 5059, 5059 50 59, 59 50-59 4049 40 49 40-4 3039 30 39 30-3 Similarly period 7079, 79, regiondependent 20 201 8 ≥ 707 7 70- 606 6 60-6 505 5 50-5 404 4 40- 303 3 30- 2 60- 50-

https://doi.org/10.1590/s2175-97902024e23366

To be or not to B27 positive: implications for the phenotypes of axial spondyloarthritis outcomes. Data from a large multiracial cohort from the Brazilian Registry of Spondyloarthritis B B2 positive outcomes
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Resende, Gustavo Gomes

; Saad, Carla Goncalves Schahin

; Marques, Claudia Diniz Lopes

; Ribeiro, Sandra Lúcia Euzébio

; Gavi, Maria Bernadete Renoldi de Oliveira

; Yazbek, Michel Alexandre

; Marinho, Adriana de Oliveira

; Menin, Rita de Cássia

; Ochtrop, Manuella Lima Gomes

; Soares, Andressa Miozzo

; Cavalcanti, Nara Gualberto

; Carneiro, Jamille Nascimento

; Werner de Castro, Glaucio Ricardo

; Fernandes, José Mauro Carneiro

; Souza, Elziane da Cruz Ribeiro E

; Alvarenga, Corina Quental de Menezes

; Vieira, Rejane Maria Rodrigues de Abreu

; Machado, Natalia Pereira

; Ximenes, Antônio Carlos

; Gazzeta, Morgana Ohira

; Albuquerque, Cleandro Pires de

; Skare, Thelma Larocca

; Keiserman, Mauro Waldemar

; Kohem, Charles Lubianca

; Benacon, Gabriel Sarkis

; Rocha, Vítor Florêncio Santos

; Lage, Ricardo da Cruz

; Malheiro, Olivio Brito

; Golebiovski, Rywka Tenenbaum Medeiros

; Oliveira, Thauana Luiza

; Duque, Ruben Horst

; Londe, Ana Carolina

; Pinheiro, Marcelo de Medeiros

; Sampaio-Barros, Percival Degrava

Advances in Rheumatology

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2024, Volume 64 elocation 33

Abstract: En | Text: En | PDF: En

Abstract Background There is a remarkable variability in the frequency of HLA-B27 positivity in patients with spondyloarthritis (SpA), which may be associated with different clinical presentations worldwide. However, there is a lack of data considering ethnicity and sex on the evaluation of the main clinical and prognostic outcomes in mixed-race populations. The aim of this study was to evaluate the frequency of HLA-B27 and its correlation with disease parameters in a large population of patients from the Brazilian Registry of Spondyloarthritis (RBE). Methods The RBE is a multicenter, observational, prospective cohort that enrolled patients with SpA from 46 centers representing all five geographic regions of Brazil. The inclusion criteria were as follow: (1) diagnosis of axSpA by an expert rheumatologist; (2) age ≥18 years; (3) classification according to ASAS axial. The following data were collected via a standardized protocol: demographic data, disease parameters and treatment historical. Results A total of 1096 patients were included, with 73.4% HLA-B27 positivity and a mean age of 44.4 (±13.2) years. Positive HLA-B27 was significantly associated with male sex, earlier age at disease onset and diagnosis, uveitis, and family history of SpA. Conversely, negative HLA-B27 was associated with psoriasis, higher peripheral involvement and disease activity, worse quality of life and mobility. Conclusions Our data showed that HLA-B27 positivity was associated with a classic axSpA pattern quite similar to that of Caucasian axSpA patients around the world. Furthermore, its absence was associated with peripheral manifestations and worse outcomes, suggesting a relevant phenotypic difference in a highly miscegenated population. HLAB27 HLAB HLA B27 B HLA-B2 SpA, , (SpA) worldwide However mixedrace mixed race populations RBE. . (RBE) multicenter observational 4 Brazil follow 1 (1 rheumatologist 2 (2 18 ≥1 years 3 (3 axial protocol historical 109 included 734 73 73.4 444 44 44. ±13.2 132 13 (±13.2 uveitis Conversely psoriasis activity mobility world Furthermore HLAB2 B2 HLA-B (SpA (RBE ( ≥ 10 7 73. ±13. (±13. ±13 (±13 ±1 (±1 ± (±

https://doi.org/10.1186/s42358-024-00372-0

Factors associated with Burnout Syndrome in police officers: a scoping review officers
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Ribeiro, Beatriz Maria dos Santos Santiago

; Scorsolini-Comin, Fabio

; Robazzi, Maria Lucia do Carmo Cruz

; Santos, Sérgio Valverde Marques dos

; Terra, Fábio de Souza

; Dalri, Rita de Cassia de Marchi Barcellos

Revista Brasileira de Enfermagem

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2024, Volume 77 N. 2 elocation e20230444

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivos: sintetizar os estudos que abordam os fatores associados à síndrome de burnout (SB) em policiais. Métodos: revisão de escopo, sem restrição temporal e de idiomas, com exportação para o EndNote, suprimindo os duplicados, e exportados para o aplicativo Rayyan, para organização, seleção dos artigos e extração dos dados. Resultados: foram identificadas 4559 publicações, com inclusão de 50 estudos. Houve predominância de pesquisas realizadas no Brasil e nos Estados Unidos. Alguns fatores laborais foram mais relacionados aos policiais quando comparados com outras profissões, como a aplicação da lei, frequência de interação com suspeitos e criminosos, ser cabo, insatisfação com a corporação e confrontos com civis. Conclusões: certos aspectos laborais contribuem para a SB, mesmo em países com melhores condições de trabalho na Segurança Pública. Recomenda-se priorizar ações de promoção da saúde para esses profissionais. Objetivos SB (SB Métodos escopo idiomas EndNote duplicados Rayyan organização dados Resultados 455 publicações 5 Unidos profissões lei criminosos cabo civis Conclusões Pública Recomendase Recomenda se profissionais 45 4

ABSTRACT Objectives: to synthesize research on factors associated with Burnout Syndrome (BS) in police officers. Methods: a scoping review was conducted without temporal or language restrictions. Data were exported to EndNote to remove duplicates and then imported into the Rayyan app for organization, article selection, and data extraction. Results: a total of 4559 publications were identified, with 50 studies included in the review. Research conducted in Brazil and the United States predominated. Certain occupational factors were found to be more closely linked to police officers compared to other professions, including law enforcement, frequency of interaction with suspects and criminals, rank, dissatisfaction with the organization, and civilian confrontations. Conclusions: certain aspects of the police profession contribute to BS, even in countries with better working conditions in public security. It is recommended to prioritize health promotion initiatives for these professionals. Objectives BS (BS Methods restrictions organization selection extraction Results 455 identified 5 predominated professions enforcement criminals rank confrontations Conclusions security professionals 45 4

RESUMEN Objetivos: sintetizar los estudios que abordan los factores asociados al síndrome de burnout (SB) en policías. Métodos: revisión de alcance, sin restricción temporal y de idiomas con exportación a EndNote, eliminación de duplicados y exportación a la aplicación Rayyan para organización, selección de artículos y extracción de datos. Resultados: se identificaron 4559 publicaciones con inclusión de 50 estudios. Hubo predominio de investigaciones realizadas en Brasil y Estados Unidos. Algunos factores laborales estuvieron más relacionados con los policías en comparación con otras profesiones, como la aplicación de la ley, la frecuencia de interacción con sospechosos y criminales, ser cabo, insatisfacción con la corporación y enfrentamientos con civiles. Conclusiones: ciertos aspectos laborales contribuyen al SB, incluso en países con mejores condiciones laborales en Seguridad Pública. Se recomienda priorizar acciones de promoción de la salud para estos profesionales. Objetivos SB (SB Métodos alcance EndNote organización datos Resultados 455 5 Unidos profesiones ley criminales cabo civiles Conclusiones Pública profesionales 45 4

https://doi.org/10.1590/0034-7167-2023-0444

Factors associated with burnout in military police officers in a city in Paraná
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Ribeiro, Beatriz Maria dos Santos Santiago

; Silva, Luiz Almeida da

; Scorsolini-Comin, Fabio

; Robazzi, Maria Lucia do Carmo Cruz

; Santos, Sérgio Valverde Marques dos

; Terra, Fábio de Souza

; Dalri, Rita de Cassia de Marchi Barcellos

Revista Brasileira de Enfermagem

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2024, Volume 77 N. 4 elocation e20230510

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: analisar a associação entre burnout e fatores sociodemográficos, laborais, hábitos de vida e condições de saúde de policiais militares de um município do estado do Paraná, Brasil. Método: pesquisa transversal com 131 policiais militares. Os dados foram analisados por meio do software Statistical Package for the Social Sciences e do programa R. Utilizaram-se os testes qui-quadrado, exato de Fisher e Modelo Linear Generalizado de Poisson. Resultados: a maioria dos participantes (65,6%) apresentou elevado índice de burnout. Em relação aos fatores protetivos, quem realizava atividades de lazer possuía 33,6% chances de não desenvolver burnout. A conjugalidade também foi um fator protetivo. Não praticar atividade física e atividades de lazer são fatores que podem contribuir para ocorrência de burnout. Conclusões: observaram-se fatores importantes e índices elevados de burnout nos policiais investigados. Faz-se necessária a implementação de políticas públicas de saúde para redução do burnout com atenção voltada a essa categoria profissional. Objetivo sociodemográficos laborais Paraná Brasil Método 13 R Utilizaramse Utilizaram se quiquadrado, quiquadrado qui quadrado, quadrado qui-quadrado Poisson Resultados 65,6% 656 65 6 (65,6% protetivos 336 33 33,6 protetivo Conclusões observaramse observaram investigados Fazse Faz profissional 1 65,6 (65,6 3 33, 65, (65, (65 (6 (

ABSTRACT Objective: to analyze the association between burnout and sociodemographic, work factors, lifestyle habits and health conditions of military police officers in a municipality in the state of Paraná, Brazil. Method: cross-sectional research with 131 military police officers. Data were analyzed using the Statistical Package for the Social Sciences software and the R program. Chi-square, Fisher’s exact and Poisson Generalized Linear Model tests were used. Results: most participants (65.6%) had a high level of burnout. In relation to protective factors, those who carried out leisure activities had a 33.6% chance of not developing burnout. Conjugality was also a protective factor. Not practicing physical activity and leisure activities are factors that can contribute to the occurrence of burnout. Conclusions: important factors and high rates of burnout were observed in the police officers investigated. It is necessary to implement public health policies to reduce burnout with attention focused on this professional category. Objective sociodemographic Paraná Brazil Method crosssectional cross sectional 13 program Chisquare, Chisquare Chi square, square Chi-square Fishers Fisher s used Results 65.6% 656 65 6 (65.6% 336 33 33.6 factor Conclusions investigated category 1 65.6 (65.6 3 33. 65. (65. (65 (6 (

RESUMEN Objetivo: analizar la asociación entre burnout y factores sociodemográficos, laborales, hábitos de vida y condiciones de salud de policías militares en un município del estado de Paraná, Brasil. Método: investigación transversal con 131 policías militares. Los datos fueron analizados mediante el software Statistical Package for the Social Sciences y el programa R. Se utilizaron las pruebas de chi-cuadrado, exacta de Fisher y Modelo Lineal Generalizado de Poisson. Resultados: la mayoría de los participantes (65,6%) presentó un alto nivel de burnout. En relación a los factores protectores, quienes realizaban actividades de ocio tenían un 33,6% de posibilidades de no desarrollar burnout. La conyugalidad era también un factor protector. La no práctica de actividad física y actividades de ocio son factores que pueden contribuir a la aparición del burnout. Conclusiones: se observaron factores importantes y altos índices de burnout en los policías investigados. Es necesario implementar políticas de salud pública para reducir el burnout con atención centrada en esta categoría profesional. Objetivo sociodemográficos laborales Paraná Brasil Método 13 R chicuadrado, chicuadrado chi cuadrado, cuadrado chi-cuadrado Poisson Resultados 65,6% 656 65 6 (65,6% protectores 336 33 33,6 protector Conclusiones investigados profesional 1 65,6 (65,6 3 33, 65, (65, (65 (6 (

https://doi.org/10.1590/0034-7167-2023-0510

Lógica Fuzzy na determinação de fragmentos florestais potenciais para coleta de sementes
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Peluzio, Telma Machado de Oliveira

; Peluzio, João Batista Esteves

; Abreu, Karla Maria Pedra de

; Ferrari, Jéferson Luiz

; Kunz, Sustanis Horn

; Fiedler, Nilton César

; Gandine, Quênia Glória Ferreira

; Paschoa, Luciana de Souza Lorenzoni

; Moura, Marks Melo

; Moreira, Giselle Lemos

; Carvalho, Rita de Cássia Freire

; Pimentel, Stefania Marques

; Branco, Elvis Ricardo Figueira

; Peluzio, Lucas Machado

; Santos, Alexandre Rosa dos

Ciência Florestal

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sep 2023, Volume 33 N. 3 elocation e70016

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO A floresta tropical é extremamente explorada e fragmentada, sendo imprescindível a coleta de sementes nativas, a fim de atender a crescente demanda para sua restauração e manutenção da biodiversidade. Dessa forma, objetiva-se selecionar fragmentos florestais potenciais com maior grau de conservação para a colheita de sementes, via utilização e associação da ecologia da paisagem à lógica Fuzzy. O estudo foi realizado na bacia hidrográfica do rio Itapemirim. Foram realizadas as etapas de seleção e fotointerpretação das imagens; determinação do erro; aplicação dos índices métricos de ecologia da paisagem; aplicação da lógica Fuzzy em aplicativo computacional e validação da metodologia in loco. Foram determinados 7.515 fragmentos florestais, correspondendo a 19,21% da área de estudo, com 89,53% de acertos. Os fragmentos menores que 5 ha são os mais frágeis e possuem risco de extinção, enquanto os maiores que 300 ha possuem menor risco de extinção, mesmo com o aumento da borda. Com a aplicação da lógica Fuzzy, a média ficou entre 0,15, desvio padrão de 0,24 e o coeficiente de variação em 161,73 %. O Cenário 1 (FLONA de Pacotuba) possui 10,25% de famílias, 25,92 % de gêneros e 33,62% de espécies a mais que o Cenário 2 (PEAMA Ifes Campus de Alegre), entre os indivíduos identificados. A associação das técnicas de ecologia da paisagem e lógica Fuzzy possibilitou identificar os fragmentos em maior grau de conservação, com potencial para colheita de sementes florestais. fragmentada nativas biodiversidade forma objetivase objetiva se Itapemirim imagens erro loco 7515 7 515 7.51 1921 19 21 19,21 8953 89 53 89,53 acertos extinção 30 borda 015 0 15 0,15 024 24 0,2 16173 161 73 161,7 FLONA Pacotuba 1025 10 25 10,25 famílias 2592 92 25,9 3362 33 62 33,62 PEAMA Alegre, Alegre , Alegre) identificados 751 51 7.5 192 19,2 895 8 89,5 3 01 0,1 02 0, 1617 16 161, 102 10,2 259 9 25, 336 6 33,6 75 7. 19, 89, 10, 33,

ABSTRACT The tropical forest is extremely exploited and fragmented, making it essential to collect native seeds to meet the growing demand for its restoration and maintenance of biodiversity. Thus, the objective is to select potential forest fragments with a higher degree of conservation for seed harvesting, through the use and association of landscape ecology with fuzzy logic. The study was carried out in the watershed of the Itapemirim river. The stages of selection and photointerpretation of the images were carried out; error determination; application of landscape ecology metric indices; application of fuzzy logic in a computational application and validation of the methodology in loco. 7,515 forest fragments were determined, corresponding to 19.21% of the study area, with 89.53% of hits. Fragments smaller than 5 ha are the most fragile and are at risk of extinction, while those larger than 300 ha have a lower risk of extinction, even with the increase in the edge. With the application of fuzzy logic, the mean was between 0.15, standard deviation of 0.24 and the coefficient of variation at 161.73%. Scenario 1 (FLONA of Pacotuba), has 10.25% of families, 25.92% of genera and 33.62% of species more than Scenario 2 (PEAMA Ifes Campus of Alegre), among the identified individuals. The association of landscape ecology techniques and fuzzy logic made it possible to identify fragments with a higher degree of conservation, with potential for harvesting forest seeds. fragmented biodiversity Thus river determination indices loco 7515 7 515 7,51 determined 1921 19 21 19.21 area 8953 89 53 89.53 hits extinction 30 edge 015 0 15 0.15 024 24 0.2 16173 161 73 161.73% FLONA Pacotuba, Pacotuba , Pacotuba) 1025 10 25 10.25 families 2592 92 25.92 3362 33 62 33.62 PEAMA Alegre, Alegre Alegre) individuals 751 51 7,5 192 19.2 895 8 89.5 3 01 0.1 02 0. 1617 16 161.73 102 10.2 259 9 25.9 336 6 33.6 75 7, 19. 89. 161.7 10. 25. 33. 161.

https://doi.org/10.5902/1980509870016

Solid-state properties of pink clay from Jequitinhonha Valley in Brazil for pre-formulation study Solidstate Solid state preformulation pre formulation
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Freitas-Marques, Maria Betânia de

; Almeida, Osmar Patrício

; Silva, Flávia Lidiane Oliveira da

; Araújo, Bárbara Caroline Rodrigues

; Ardisson, José Domingos

; Sebastião, Rita de Cássia de Oliveira

; Mussel, Wagner da Nova

; Yoshida, Maria Irene

; Carneiro, Guilherme

Brazilian Journal of Pharmaceutical Sciences

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2023, Volume 59 elocation e21460

Abstract: En | Text: En | PDF: En

Abstract Clay minerals are still widely used in pharmaceutical products for human health and cosmetic purposes. Pre-formulation studies were conducted to identify solid-state properties of pink clay, a sample from Diamantina, Brazil. Among the solid properties to be analyzed, we have selected type identification, iron phases, crystallinity, powder flow characteristics, thermal behavior, and non-isothermal phase transition kinetics. The pink clay is composed of (1:1) clay type and kaolinite as the main component. The Mössbauer spectrum of pink clay shows Fe3+(α-Fe2O3) hematite, Fe2+, and Fe3+ with large Δ/2ξq of about 2.80 and 2.69 mm.s-1 respectively, related to iron silicates, most likely pyroxene, and a superparamagnetic Fe3+. Pink clay exhibits poor flow properties. The thermal behavior indicates a phase-transition between 400 - 600 ºC associated with the dehydroxylation of the pink clay system requiring ~300 kJ mol-1, being constant until the process reaches a conversion of ~50% when the energy is enhanced to ~530 kJ mol-1, concluding the whole dehydroxylation process (α=80%). Solid-state properties and characteristics found for the pink clay must be considered for the proper design of formulations. This type of clay shows unique pharmaceutical properties that can be favorably exploited by the cosmetic industry. purposes Preformulation Pre formulation solidstate state Diamantina Brazil analyzed identification phases crystallinity nonisothermal non isothermal kinetics 11 1 (1:1 component Fe3+αFe2O3 Fe3αFe2O3 FeαFeO α Fe2O3 Fe3 Fe O Fe3+(α-Fe2O3 hematite Fe2 Fe2+ Δ2ξq Δξq Δ 2ξq ξq 280 2 80 2.8 269 69 2.6 mm.s1 mms1 mms mm.s mm s mm.s- respectively silicates pyroxene phasetransition 40 60 300 ~30 mol1, mol1 mol 1, mol-1 50 ~50 530 ~53 α=80%. α80 α=80% . (α=80%) Solidstate Solid formulations industry (1: αFe2O3 αFe Fe3+αFe2O Fe3αFe2O FeO Fe2O Fe3+(α-Fe2O 28 8 2. 26 6 s1 4 30 ~3 mol- 5 ~5 53 α8 α=80 (α=80% (1 αFeO αFe2O 3 ~ α=8 (α=80 ( α= (α=8 (α= (α

https://doi.org/10.1590/s2175-97902023e21460

Telas na Infância: Postagens de Especialistas em Grupos de Cuidadores no Facebook Infância
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Puccinelli, Mariana Farias

; Marques, Fernanda Martins

; Lopes, Rita de Cássia Sobreira

Psicologia: Ciência e Profissão

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2023, Volume 43 elocation e253741

Abstract: Es Pt En | Text: Es Pt En | PDF: Es | PDF: Pt | PDF: En

Resumen A pesar de las crecientes investigaciones sobre el uso de pantallas en la infancia, este es un tema complejo y aún reciente, que plantea varios desafíos para investigadores y cuidadores. Las comunidades virtuales en las redes sociales son utilizadas por madres y padres para aclarar dudas y recibir consejos sobre educación y salud infantil, pudiendo, al mismo tiempo, asumir un rol prescriptivo y normativo sobre su forma de actuar. Por lo tanto, este estudio tuvo como objetivo comprender cómo el uso de las pantallas en la infancia ha sido abordado por especialistas en grupos de madres y padres en Facebook. Se realizó un estudio cualitativo a partir de 49 publicaciones de especialistas, principalmente de psicólogos y educadores, extraídas de cinco grupos públicos de madres y padres en esta red social. Se realizó en los textos de las publicaciones un análisis temático y se utilizó el marco teórico psicoanalítico. Los resultados mostraron que los expertos destacan posibles daños que provoca el uso de pantallas en la infancia, además de orientar a los padres sobre cómo afrontar esta presencia de la tecnología digital en el día a día de los niños y sus familias. Se concluyó que, a pesar de que los grupos de cuidadores en Facebook son una herramienta de difusión de información sobre el uso de pantallas en la infancia, es importante no naturalizar la presencia de especialistas en estos espacios virtuales creados por padres y madres que se interpone entre los saberes e intercambios horizontales de los cuidadores. reciente infantil pudiendo tiempo actuar tanto 4 educadores social psicoanalítico familias

Resumo Apesar das crescentes investigações sobre uso de telas na infância, essa é uma temática complexa e ainda recente, que traz diversos desafios para pesquisadores e cuidadores. Comunidades virtuais em redes sociais são utilizadas por mães e pais para esclarecer dúvidas e receber conselhos acerca da parentalidade e saúde infantil, podendo, simultaneamente, assumir uma função prescritiva e normativa quanto ao seu modo de agir. Sendo assim, este artigo pretende compreender como o uso de telas na infância vem sendo abordado por especialistas em grupos de mães e pais no Facebook. Foi realizado um estudo qualitativo envolvendo 49 postagens de especialistas, sobretudo psicólogos e educadores, extraídas de cinco grupos públicos de mães e pais nessa rede social. Os textos das publicações foram verificados por meio de análise temática e discutidos com base no referencial teórico psicanalítico. Os resultados mostraram que os especialistas destacam os possíveis prejuízos do uso de telas na infância, além de fornecer orientações aos pais sobre como lidar com sua presença no cotidiano das crianças e de suas famílias. Concluiu-se que apesar dos grupos de cuidadores no Facebook serem uma ferramenta de divulgação de informações acerca do uso de telas na infância, cabe não naturalizar a presença de especialistas nesses espaços virtuais criados por pais e mães, interpondo-se nos saberes e nas trocas horizontalizadas entre os cuidadores. recente infantil podendo simultaneamente agir assim 4 educadores social psicanalítico famílias Concluiuse Concluiu se interpondose interpondo

Abstract Although investigations on the use of screens in childhood are increasing, this is a complex and recent topic, which poses several challenges for researchers and caregivers. Virtual communities in social networks are used by mothers and fathers to clarify doubts and receive advice regarding parenting and child health, at times, simultaneously, assuming a prescriptive and normative role on their way of acting. Therefore, this study aimed to understand how the use of screens in childhood has been approached by experts in groups of mothers and fathers on Facebook. A qualitative study was carried out involving 49 posts from specialists, mainly psychologists and educators, extracted from five public groups of mothers and fathers in this social network. The publications’ texts were verified via thematic analysis and discussed based on the psychoanalytical theoretical framework. The results showed that experts highlight the possible damage of the use of screens in childhood, in addition to providing guidance to parents on how to deal with the presence of digital technology in the daily lives of children and families. It was concluded that, although caregivers’ groups on Facebook are a tool for disseminating information about the use of screens in childhood, it is important not to naturalize the presence of specialists in these virtual spaces created by fathers and mothers, interposing in the horizontally interchanges that occur between the caregivers. increasing topic caregivers health times simultaneously acting Therefore 4 educators network publications framework families

https://doi.org/10.1590/1982-3703003253741

10.

Charcot-Marie-Tooth disease: from historical landmarks in Brazil to current care perspectives CharcotMarieTooth Charcot Marie Tooth disease
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Cavalcanti, Eduardo Boiteux Uchôa

; Leal, Rita de Cássia Carvalho

; Marques Junior, Wilson

; Nascimento, Osvaldo José Moreira do

Arquivos de Neuro-Psiquiatria

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2023, Volume 81 N. 10 Pages 913 - 921

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A neuropatia sensitivo-motora hereditária, também conhecida como doença de Charcot-Marie-Tooth (CMT), tradicionalmente se refere a um grupo de doenças genéticas em que a neuropatia é a principal ou única manifestação. Sua prevalência varia de acordo com as diferentes populações estudadas, com estimativa entre 1:2.500 a 1:10.000. Desde a identificação da duplicação do gene PMP22 no cromossomo 17, por Vance et al., em 1989, mais de 100 genes foram relacionados a esse grupo de doenças e temos visto avanços no atendimento aos pacientes, com identificação de condições associadas e melhores tratamentos de suporte, incluindo intervenções clínicas e cirúrgicas. Além disso, com as descobertas no campo da genética, incluindo técnicas de interferência de RNA e de edição genética, novas perspectivas de tratamento começaram a surgir. No presente trabalho, relatamos os marcos mais importantes sobre a pesquisa de CMT no Brasil e fornecemos uma revisão abrangente sobre tópicos como frequência de diferentes genes associados à CMT em nossa população, prevalência de dor, impacto na gravidez, alterações respiratórias e desenvolvimento de novas terapias. sensitivomotora sensitivo motora hereditária CharcotMarieTooth Charcot Marie Tooth CMT, , (CMT) manifestação estudadas 12.500 12500 1 2.500 2 500 1:2.50 110.000. 110000 10.000. 10 000 1:10.000 PMP PMP2 17 al al. 1989 pacientes suporte cirúrgicas disso genética surgir trabalho população dor gravidez terapias (CMT 12 12.50 1250 2500 2.50 50 1:2.5 110 110.000 11000 10000 10.000 00 1:10.00 198 12.5 125 250 2.5 5 1:2. 11 110.00 1100 1000 10.00 0 1:10.0 19 12. 25 2. 1:2 110.0 10.0 1:10. 1: 110. 10. 1:10 1:1

Abstract Hereditary motor and sensory neuropathy, also known as Charcot-Marie-Tooth disease (CMT), traditionally refers to a group of genetic disorders in which neuropathy is the main or sole feature. Its prevalence varies according to different populations studied, with an estimate between 1:2,500 to 1:10,000. Since the identification of PMP22 gene duplication on chromosome 17 by Vance et al., in 1989, more than 100 genes have been related to this group of disorders, and we have seen advances in the care of patients, with identification of associated conditions and better supportive treatments, including clinical and surgical interventions. Also, with discoveries in the field of genetics, including RNA interference and gene editing techniques, new treatment perspectives begin to emerge. In the present work, we report the most import landmarks regarding CMT research in Brazil and provide a comprehensive review on topics such as frequency of different genes associated with CMT in our population, prevalence of pain, impact on pregnancy, respiratory features, and development of new therapies. CharcotMarieTooth Charcot Marie Tooth CMT, , (CMT) feature studied 12,500 12500 1 2,500 2 500 1:2,50 110,000. 110000 10,000. 10 000 1:10,000 PMP PMP2 al al. 1989 patients treatments interventions Also genetics techniques emerge work population pain pregnancy features therapies (CMT 12 12,50 1250 2500 2,50 50 1:2,5 110 110,000 11000 10000 10,000 00 1:10,00 198 12,5 125 250 2,5 5 1:2, 11 110,00 1100 1000 10,00 0 1:10,0 19 12, 25 2, 1:2 110,0 10,0 1:10, 1: 110, 10, 1:10 1:1

https://doi.org/10.1055/s-0043-1770348

11.

How do relocation time and length of storage after relocation affect fermentation and nutritive value of corn silage? silage
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Santos, Rosana Ingrid Ribeiro dos

; Mendonça, Rita de Cássia Almeida de

; Queiroz, Amanda Caroliny Marques de

; Bernardes, Thiago Fernandes

; Domingues, Felipe Nogueira

; Faturi, Cristian

; Silva, Thiago Carvalho da

; Rêgo, Aníbal Coutinho do

Revista Brasileira de Zootecnia

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2023, Volume 52 elocation e20220059

Abstract: En | Text: En | PDF: En

ABSTRACT This study aimed to determine the effects of relocation time (RT; Experiment 1) and storage time after relocation (ST; Experiment 2) on microbial population, fermentative characteristics, and chemical composition of corn silage. In experiment 1, corn silage was stored for 30 d, subjected to different RT (0–60 h), and stored again for 30 d. Thirty experimental silos were used in a completely randomized design, with three replicates per treatment. In experiment 2, after 150 d of ensiling, silage was removed from a bunker silo, exposed to air for 9 h, relocated to experimental silos, and stored for periods ranging from 0 to 128 d. Twenty-eight experimental silos were used in a completely randomized design, with four replicates per treatment. Relocation time had no effect on fungi counts and concentrations of lactic and propionic acids in corn silage but resulted in a significant increase in dry matter content. In experiment 2, dry matter recovery and concentration of non-fiber carbohydrates decreased in corn silage stored for more than 32 d after relocation. Exposure of corn silage to air during relocation for up to 60 h followed by 30 d of storage did not compromise the fermentation profile or nutritive value of the silage. Increased storage time of relocated corn silage (up to 128 d) consistently decreases its nutritional value. The storage period seems to have an increased impact on nutrient loss in relocated silage than the relocation period. (RT 1 ST (ST 2 population characteristics 3 0–60 060 (0–6 , h) design treatment 15 ensiling silo 12 Twentyeight Twenty eight content nonfiber non fiber 6 0–6 06 (0– 0– (0 (

https://doi.org/10.37496/rbz5220220059

12.

O enfermeiro-mor nas Santas Casas da província de Minas Gerais: entre a administração e a assistência
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Marques, Rita de Cassia

; Silveira, Anny Jackeline Torres

Ciência & Saúde Coletiva

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sep 2022, Volume 27 N. 9 Pages 3419 - 3428

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Este artigo trata da percepção da enfermagem como uma ocupação de baixo prestígio no século XIX. A história da enfermagem produzida pelos profissionais da área reforçou essa concepção. No entanto, o perfil do cargo de enfermeiro-mor, presente nas Santas Casas, indica um espectro social mais amplo para a profissão de enfermagem. As autoras defendem a hipótese de que essa avaliação negativa se baseia apenas em atividades de cuidado ao paciente que eram mais visíveis. A presença do enfermeiro-mor exemplifica os limites de uma generalização da desvalorização social da enfermagem. A conclusão é que a suposição generalizada de que a enfermagem se limitava a cuidados básicos de saúde não se sustenta.

Abstract This article focuses on the perception of nursing as a low-prestige occupation in the 19th century. The history of nursing produced by professionals in the area supported this understanding. However, the profile of the enfermeiro-mor (head nurse), a position in the Santas Casas, demonstrates that the nursing profession was present throughout a broader social spectrum. The authors support the hypothesis that the typical negative assessment is based only on the more visible patient care activities. The presence of the enfermeiro-mor exemplifies the limits of a generalization of the social undervaluation of nursing. The conclusion is that the generalized assumption that nursing was only about basic health care is not acceptable.

https://doi.org/10.1590/1413-81232022279.04652022

13.

O enfermeiro-mor nas Santas Casas da província de Minas Gerais: entre a administração e a assistência
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Marques, Rita de Cassia

; Silveira, Anny Jackeline Torres

Ciência & Saúde Coletiva

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sep 2022, Volume 27 N. 9 Pages 3419 - 3428

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1413-81232022279.04652022

14.

Ingestive behavior of lambs fed relocated and inoculated whole-plant corn silage
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Cardoso, Marcus Vinicius Santa Brígida

; Mendonça, Rita de Cássia Almeida de

; Queiroz, Amanda Caroliny Marques

; Ferreira, Cláudia Márcia Serra

; Santos, Rosana Ingrid Ribeiro dos

; Faturi, Cristian

; Domingues, Felipe Nogueira

; Rêgo, Aníbal Coutinho do

Acta Scientiarum. Animal Sciences

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2022, Volume 44 elocation e53714

Abstract: En | Text: En | PDF: En

ABSTRACT. We aimed to determine the effect of relocation of whole-plant corn silage (WPCS) with different fermentation profiles on ingestive behavior of lambs. Twenty-four male Santa Inês lambs, were used in a completely randomized block design based on initial body weight (17.5 ± 1.8 kg) for the following treatments: CS: WPCS (not inoculated and not relocated); R-12h: WPCS relocated for 12h; IR-12h: WPCS inoculated with Lactobacillus plantarum and relocated for 12h; and R-24h: WPCS not inoculated and relocated for 24h. Ingestive behavior was observed as continuous (feeding, ruminating, and idling) and specific (urination, defecation, and water and salt access frequency) activities for 48h (3h intervals for a total of eight periods in 24h). The behavioral activities were affected only by periods (p = 0.0001). Feeding peaks was high at 8:00-11:00am (54.2%) and 5:00-8:00pm (54.9%) in compare to ruminating and idling at the same period. Rumination time was intense at night, at 63.7% (2:00-5:00am) and 69.7% (5:00-8:00am). Idling time (49.7%) was long after silage supply. The specific activities were intense during the morning periods. Supply of WPCS relocated up to 24h did not alter the ingestive behavior.

https://doi.org/10.4025/actascianimsci.v44i1.53714

15.

Brazilian nursing in pandemic times and the bicentennial of Florence Nightingale
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Ribeiro, Beatriz Maria dos Santos Santiago

; Scorsolini-Comin, Fabio

; Santos, Sérgio Valverde Marques dos

; Dalri, Rita de Cassia de Marchi Barcellos

Revista Brasileira de Enfermagem

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2022, Volume 75 Suppl. 1 elocation e20210081

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: Refletir sobre a atuação da enfermagem brasileira durante a pandemia de COVID-19, tendo como marco histórico o bicentenário de nascimento de Florence Nightingale, precursora da enfermagem moderna, comemorado em 2020. Método: Estudo teórico-reflexivo, fundamentado na teoria ambientalista de Florence Nightingale, por meio de revisão de literatura realizada em noticiários virtuais, internacionais e nacionais, de diferentes fontes. Além disso, dos autores foram acrescidas as experiências relacionadas à pandemia. Resultados: Possibilitou identificar as fragilidades experimentadas pelos profissionais de enfermagem quanto ao contágio pela COVID-19, da rotina de exposição aos riscos, da ausência de proteção adequada em muitos cenários, das elevadas taxas de adoecimento e também de óbitos ocorridos nessa profissão. Considerações finais: A Teoria Ambientalista de Florence Nightingale descreve a importância da adequação do ambiente laboral. Assim como, enfatiza o valor da profissional para a enfermagem contemporânea e também para a ressignificação dessa categoria profissional durante a pandemia da COVID-19.

ABSTRACT Objective: To reflect on the role of Brazilian nursing during the COVID-19 pandemic, considering as a historical landmark the bicentenary of the birth of Florence Nightingale, a precursor of modern nursing, celebrated in 2020. Method: Theoretical-reflective study, based on Florence Nightingale’s environmental theory through a literature review, carried out in international and national virtual news from different sources and added to the authors’ experiences related to the pandemic. Results: It was possible to identify the weaknesses experienced by nurse practitioners as to contagion by COVID-19, the routine of exposure to risks, the lack of adequate protection in many scenarios, the high rates of illness, and also deaths that occurred in this profession. Final considerations: Florence Nightingale’s Environmental Theory describes the importance of the adequacy of the work environment. It also emphasizes the value of this professional for contemporary nursing and the redefinition of this professional category during the COVID-19 pandemic.

RESUMEN Objetivo: Reflejar sobre la actuación de la enfermería brasileña durante la pandemia de COVID-19, teniendo como marco histórico el bicentenario del nacimiento de Florence Nightingale, precursora de la enfermería moderna, conmemorado en 2020. Método: Estudio teórico-reflexivo, fundamentado en la teoría ambientalista de Florence Nightingale por medio de una revisión de la literatura, realizada en noticieros virtuales nacionales e internacionales de diferentes fuentes y sumado a las experiencias de los autores relacionadas a la pandemia. Resultados: Posibilitó identificar las fragilidades experimentadas por los profesionales de la enfermería en cuanto al contagio por COVID-19, de la rutina de exposición a los riesgos, de la ausencia de protección adecuada en muchos escenarios, de las elevadas tasas de contagio y también de muertes ocurridas en esa profesión. Consideraciones finales: La Teoría Ambientalista de Florence Nightingale describe la importancia de la adecuación del ambiente laboral. Se enfatiza también el valor de esta profesional para la enfermería contemporánea y para la resignificación de esa categoría profesional durante la pandemia de COVID-19.

https://doi.org/10.1590/0034-7167-2021-0081 136 downloads

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