Resumo Enquadramento: As ambulâncias de suporte imediato de vida (SIV) possibilitam ao enfermeiro capacidade de intervenção em contexto pré-hospitalar, suportada pelo seu conhecimento técnico-científico, protocolos complexos de atuação e regulação médica por telemedicina. Objetivo: Analisar os contributos da intervenção dos enfermeiros SIV, na evolução do estado clínico da pessoa em situação crítica (PSC). Metodologia: Estudo quantitativo, descritivo-correlacional, retrospetivo, realizado em meios SIV, na região norte de Portugal. Analisados 574 registos clínicos eletrónicos, entre 01 de novembro e 31 de dezembro de 2019, que correspondem ao mesmo número de pessoas avaliadas. Utilizada a escala National Early Warning Score (NEWS) para avaliar a evolução clínica da PSC. Resultados: Observou-se uma evolução positiva do score NEWS da PSC, após a intervenção do enfermeiro SIV (M = 4,43 ± 3,901 vs 3,34 ± 3,329; sig < 0,001). Em sentido inverso, o risco clínico diminuiu significativamente após a intervenção do enfermeiro. Conclusão: Demonstrou-se a relevância da intervenção do enfermeiro SIV no contexto pré-hospitalar, enquanto garantia de segurança, qualidade e melhoria contínua dos cuidados à PSC.

Abstract Background: Immediate life support (ILS) ambulances allow nurses to intervene in pre-hospital settings, supported by their technical-scientific knowledge and complex protocols of action and regulation through telemedicine. Objective: To analyze the contributions of nursing interventions in the evolution of the clinical state of critical patients. Methodology: Quantitative, descriptive-correlational, retrospective, and observational study conducted in ILS settings in northern Portugal. A total of 574 electronic clinical records were analyzed between 1 November and 31 December 2019, corresponding to the same number of people evaluated. The National Early Warning Score (NEWS) was used to assess the clinical evolution of critical patients. Results: There was a positive evolution of the NEWS score of critical patients after the intervention of ILS nurses (M = 4.43 ± 3.901 vs. 3.34 ± 3.329; sig < 0.001). Similarly, the clinical risk of critical patients decreased after the nurse’s intervention. Conclusion: This study demonstrated the importance of nurses in prehospital care, as a guarantee of safety, quality, and continuous improvement of care for critical patients.

Resumen Marco contextual: Las ambulancias de soporte vital inmediato (SVI) permiten al personal de enfermería intervenir en un contexto prehospitalario, con el apoyo de sus conocimientos técnico-científicos y de complejos protocolos de actuación y regulación médica a través de la telemedicina. Objetivo: Analizar las aportaciones de la intervención del personal de enfermería del SVI en la evolución del estado clínico de la persona en situación crítica (PSC). Metodología: Estudio cuantitativo, descriptivo-correlacional, retrospectivo, realizado en centros de SVI del norte de Portugal. Se analizaron 574 historias clínicas electrónicas entre el 1 de noviembre y el 31 de diciembre de 2019, correspondientes al mismo número de personas evaluadas. Se utilizó la escala National Early Warning Score (NEWS) para evaluar la evolución clínica de la PSC. Resultados: Se observó una evolución positiva en el score NEWS de la PSC, tras la intervención del personal de enfermería del SVI (M = 4,43 ± 3,901 vs 3,34 ± 3,329; sig < 0,001). Por el contrario, el riesgo clínico disminuyó significativamente tras la intervención del personal de enfermería. Conclusión: Se demostró la relevancia de la intervención del personal de enfermería del SVI en el contexto prehospitalario, como garantía de seguridad, calidad y mejora continua en la atención a la PSC.

ABSTRACT. This study aimed to assess the impact of microalgal concentrations in diets on the settlement and metamorphosis stages of pediveliger larvae and spat of Crassostrea gigas oysters. Diets containing microalgal concentrations of 8, 12, and 16×104 cells mL-1 were administered for seven days during the larval settlement phase of pediveliger larvae. In the metamorphosis and postlarval cultivation phases, diets with microalgal concentrations of 8, 16, 24, and 32×104 cells mL-1 and a control group without food were tested for 14 and 21 days, respectively. Growth, yield, and survival were assessed every seven days. The diet comprised 30% Isochrysis galbana and 70% Chaetoceros muelleri microalgae. In the metamorphosis phase, the results revealed no significant differences in larval metamorphosis rate and survival across the tested diets. The concentrations exhibited similar survival in the spat with an initial average shell height of 0.657 ± 0.05 mm, with a significant difference only in growth. In the spat with an initial average shell height of 0.830 ± 0.12 mm, no differences in survival were observed among the tested concentrations. We concluded that diets of 12 and 16×104 cells mL-1 provide high rates of larval metamorphosis and spat yield during the larval settlement and metamorphosis phases. During the spat cultivation phases, diets of 32 and 24×104 cells mL-1 could optimize the cultivation time and yield of C. gigas spat in the laboratory. However, when considering survival alone, no advantage was found in providing a diet with a microalgal concentration above 8×104 cells mL-1 across all C. gigas oyster cultivation phases.

Resumen El tinnitus, una percepción auditiva subjetiva sin fuente externa, es comúnmente asociado a hipoacusia, que puede ser secundaria a múltiples etiologías. Sin embargo, en ocasiones, el tinnitus puede ser el resultado de causas menos comunes y más desafiantes de diagnosticar. Presentamos el caso de una paciente de 48 años con tinnitus pulsátil persistente cuya etiología fue revelada incidentalmente como un hallazgo inusual tras la evaluación clínica y diagnóstica, reconociéndose como origen la presencia de una arteria carótida interna (ACI) aberrante. Este caso destaca la importancia de considerar causas poco frecuentes de tinnitus en el proceso diagnóstico y resalta la complejidad a la hora de su abordaje.

Abstract Tinnitus, a subjective auditory perception without an external source, is commonly associated with hearing loss, which can be secondary to multiple etiologies. However, sometimes tinnitus can result from less common and more challenging causes to diagnose. We present the case of a 48-year-old female patient with persistent pulsatile tinnitus, whose etiology was incidentally revealed as an unusual finding following clinical and diagnostic evaluation, identified as originating from the presence of an aberrant internal carotid artery (ICA). This case highlights the importance of considering uncommon causes of tinnitus in the diagnostic process and underscores the complexity of its management.

Resumo Nas últimas décadas, tem sido discutida a elevada prevalência de exaustão (burnout) na Medicina, incluindo na Imagiologia. No entanto, em Portugal, ainda há poucos dados sobre este problema. Além disso, fenómenos como a síndrome do impostor e as microagressões têm sido cada vez mais reconhecidos como negativos para a saúde e bem-estar dos radiologistas. Este estudo inovador em Portugal investigou a presença de microagressões, sofrimento ético e por fenómeno impostor entre radiologistas. Os resultados foram particularmente significativos em grupos que trabalham em situações de urgência, salientando a necessidade de melhorias nas condições de trabalho e medidas para combater esses importantes problemas.

Abstract In recent decades, the high prevalence of burnout in medicine, including radiology, has been discussed. However, there is still little data on this problem in Portugal. In addition, phenomena such as impostor syndrome and microaggressions have been increasingly recognized as negative for radiologists' health and well-being. This innovative study in Portugal investigated the presence of microaggressions, ethical distress and impostor syndrome among Radiologists. The results were particularly significant in groups working in emergency situations, emphasizing the need for improvements in working conditions and measures to combat these major problems.

ABSTRACT Purpose The clinical outcomes of kidney transplantation from deceased donors have seen significant improvements with the use of machine perfusion (MP), now a standard practice in transplant centers. However, the use of perfusate biomarkers for assessing organ quality remains a subject of debate. Despite this, some centers incorporate them into their decision-making process for donor kidney acceptance. Recent studies have indicated that lactate dehydrogenase (LDH), glutathione S-transferase, interleukin-18, and neutrophil gelatinase-associated lipocalin (NGAL) could predict post-transplant outcomes. Materials and Methods Between August 2016 and June 2017, 31 deceased-donor after brain death were included and stroke was the main cause of death. Pediatric patients, hypersensitized recipients were excluded. 43 kidneys were subjected to machine perfusion. Perfusate samples were collected just before the transplantation and stored at -80ºC. Kidney transplant recipients have an average age of 52 years, 34,9% female, with a BMI 24,6±3,7. We employed receiver operating characteristic analysis to investigate associations between these perfusate biomarkers and two key clinical outcomes: delayed graft function and primary non-function. Results The incidence of delayed graft function was 23.3% and primary non-function was 14%. A strong association was found between NGAL concentration and DGF (AUC=0.766, 95% CI, P=0.012), and between LDH concentration and PNF (AUC=0.84, 95% CI, P=0.027). Other perfusate biomarkers did not show significant correlations with these clinical outcomes. Conclusion The concentrations of NGAL and LDH during machine perfusion could assist transplant physicians in improving the allocation of donated organs and making challenging decisions regarding organ discarding. Further, larger-scale studies are required. MP, MP , (MP) However debate this decisionmaking decision acceptance LDH, (LDH) Stransferase, Stransferase S transferase, transferase S-transferase interleukin18, interleukin18 interleukin 18, 18 interleukin-18 gelatinaseassociated gelatinase associated (NGAL posttransplant post 201 2017 3 deceaseddonor patients excluded 4 80ºC. 80ºC ºC -80ºC 5 years 349 34 9 34,9 female 24637 24 6 7 24,6±3,7 nonfunction. nonfunction non function. 233 23 23.3 14 14% AUC=0.766, AUC0766 AUC 0 766 (AUC=0.766 95 CI P=0.012, P0012 P P=0.012 012 P=0.012) AUC=0.84, AUC084 84 (AUC=0.84 P=0.027. P0027 P=0.027 . 027 P=0.027) discarding Further largerscale larger scale required (MP (LDH interleukin1 1 interleukin-1 20 34, 2463 2 24,6±3, 23. AUC=0.766 AUC076 76 (AUC=0.76 P001 P=0.01 01 AUC=0.84 AUC08 8 (AUC=0.8 P002 P=0.02 02 interleukin- 246 24,6±3 AUC=0.76 AUC07 (AUC=0.7 P00 P=0.0 AUC=0.8 AUC0 (AUC=0. 24,6± AUC=0.7 P0 P=0. AUC=0. (AUC=0 24,6 P=0 AUC=0 (AUC= 24, P= AUC= (AUC

ABSTRACT: Pendimentalin is an herbicide used in short-cycle crops. Its indiscriminate use reduces the beneficial population of microorganisms in production systems. The objective of this work was to evaluate the effect of pendimentalin on the cell growth of rhizobacteria. The research was conducted at the Laboratory of Microbiology and Molecular Biology of the State Technical University of Quevedo, where the following experiments with pendimentalin contamination were carried out: 1) Adaptability of rhizobacteria under in vitro conditions; 2) Tolerance levels of rhizobacteria under different abiotic conditions in vitro; 3) Reduction of stress by rhizobacteria in soils. The rhizobacteria show a higher adaptability at 72 h with absorbance of 2.38 and 2.51 in the strains (CHA0, BA4-19, B03-4, PM3-14 and R4), also during this time they establish a neutral pH, despite the acidic and alkaline conditions. Strain CHA0 presented the highest number of cells under neutral pH (1.09E+09 CFU/mL). Strains BA4-19 and PM3-14 showed a slight improvement in morphological aspects. Rhizobacteria have adaptability at the in vitro level, but their use slightly reduces the toxicity of the herbicide in rice germination and growth processes.

RESUMEN: La pendimentalina es un herbicida usado en cultivos de ciclo corto. Su uso indiscrimado reduce la población benéfica de microorganismos en los sistemas productivos. El objetivo del trabajo fue evaluar el efecto de la pendimentalina sobre el crecimiento celular de rizobacterias. La investigación se realizó en el Laboratorio de Microbiología y Biología Molecular de la Universidad Técnica Estatal de Quevedo, donde se realizaron los siguientes experimentos con contaminación de pendimentalina: 1) Adaptabilidad de las rizobacterias en condiciones in vitro; 2) Niveles de tolerancia de las rizobacterias bajo diferentes condiciones abióticas in vitro; 3) Reducción de estrés por rizobacterias en suelos. Las rizobacterias presentan una mayor adaptabilidad a las 72 h con absorbancia de 2,38 y 2,51 en las cepas (CHA0, BA4-19, B03-4, PM3-14 y R4), además durante este tiempo establecen un pH neutro, a pesar de las condiciones ácidas y alcalinas. La cepa CHA0 presentó mayor número de células bajo pH neutro (1,09E+09 UFC/mL). Las cepas BA4-19 y PM3-14 demuestra una leve mejoría en los aspectos morfológicos. Las rizobacterias tienen una adaptabilidad a nivel in vitro, pero su uso disminuye levemente la toxicidad del herbicida en procesos de germinación y crecimiento de arroz.

RESUMEN Introducción: en el ámbito internacional, se han realizado numerosas investigaciones que han explorado la asociación entre la HTA y la sarcopenia en adultos mayores ambulatorios. Estos estudios han proporcionado evidencia sólida sobre la relación entre ambas condiciones. Objetivo: caracterizar las tendencias e impacto de la producción científica sobre hipertensión en adultos mayores ambulatorios con progresión a la sarcopenia publicada en Scopus entre 2020 y 2023 en el contexto latinoamericano. Métodos: se realizó un estudio observacional, descriptivo, transversal y bibliométrico de la producción científica latinoamericana sobre hipertensión en adultos mayores ambulatorios con progresión a la sarcopenia publicada en Scopus entre 2020 y 2023. Los datos utilizados en el estudio en cuestión se obtuvieron a partir de la base de datos Dimensions (https://www.dimensions.ai/). Se usó la correlación lineal de Pearson para realizar el análisis tendencial de los datos, la misma se realizó a través de los complementos de Excel. Resultados: los años más productivos fueron el 2020 (223 artículos) y el 2021 (187 artículos). Se recibieron un total de 20854 citas por cada artículo científico publicado. Países como Brasil y Argentina encabezan el ranking con un mayor número de investigaciones. Cuba se encontró en lugar número ocho de Latinoamérica en la publicación de artículos sobre hipertensión y sarcopenia. Conclusiones: se evidenció una baja producción científica latinoamericana sobre hipertensión en adultos mayores ambulatorios con progresión a la sarcopenia en revistas indexadas en Scopus, con artículos publicados y citas que siguen una línea directa hacia la disminución. Países como Brasil y Argentina encabezan el ranking de áreas con mayor número de investigaciones.

ABSTRACT Introduction: at the international level, numerous investigations have been carried out that have explored the association between hypertension and sarcopenia in outpatient older adults. These studies have provided solid evidence on the relationship between the two conditions. Objective: to characterize the trends and impact of scientific production on hypertension in outpatient older adults with progression to sarcopenia published in Scopus between 2020 and 2023 in the Latin American context. Methods: an observational, descriptive, transversal and bibliometric study was carried out of the Latin American scientific production on hypertension in outpatient older adults with progression to sarcopenia published in Scopus between 2020 and 2023. The data used in the study in question was obtained from the Dimensions database (https://www.dimensions.ai/). Pearson's linear correlation was used to perform the trend analysis of the data, it was done through the Excel add-ins. Results: the most productive years were 2020 (223 articles) and 2021 (187 articles). A total of 20854 citations were received for each scientific article published. Countries such as Brazil and Argentina lead the ranking with a greater number of investigations. Cuba was ranked number eight in Latin America in the publication of articles on hypertension and sarcopenia. Conclusions: there was evidence of a low Latin American scientific production on hypertension in outpatient older adults with progression to sarcopenia in journals indexed in Scopus, with published articles and citations that follow a direct line towards the decrease. Countries such as Brazil and Argentina lead the ranking of areas with the highest number of research.

ABSTRACT The National University and, particularly, the graduate school, have the task of providing a quality service that generates satisfaction among its students. This is essential to improve the quality of graduate programs. This research aims to establish whether satisfaction with the quality of university service in postgraduate students is related. To achieve this, a non-experimental, correlational and transversal design was used with a sample of 180 students, to whom the questionnaire on quality of university service and the questionnaire on user satisfaction were administered. The results obtained allow us to conclude that there are significant relationships between the two study variables (r = 0.80), as well as between their dimensions that make up each variable.

RESUMO A Universidade Nacional e, particularmente, a pós-graduação, têm a missão de prestar um serviço de qualidade que gere satisfação aos seus alunos. Isso é essencial para melhorar a qualidade dos programas de pós-graduação. Esta pesquisa tem como objetivo estabelecer se a satisfação com a qualidade do serviço universitário em estudantes de pós-graduação está relacionada. Para isso, utilizou-se um desenho não experimental, correlacional e transversal com uma amostra de 180 estudantes, aos quais foram aplicados o questionário sobre qualidade do serviço universitário e o questionário sobre satisfação do usuário. Os resultados obtidos permitem-nos concluir que existem relações significativas entre as duas variáveis do estudo (r = 0,80), bem como entre as suas dimensões que compõem cada variável.

RESUMEN La Universidad Nacional y, particularmente, la escuela de posgrado, tienen la tarea de brindar un servicio de calidad que genere satisfacción entre sus estudiantes. Esto es fundamental para mejorar la calidad de los programas de posgrado. La investigación tuvo como objetivo establecer la relación que existen entre la calidad del servicio universitario ofrecido con la satisfacción del usuario en estudiantes de posgrado de una Universidad Pública de Lima. Para lograrlo se utilizó un diseño no experimental, correlacional y transversal con una muestra de 180 estudiantes, a quienes se les administró el cuestionario sobre calidad del servicio universitario y el cuestionario sobre satisfacción del usuario. Los resultados obtenidos permitieron concluir que, existen relaciones significativas entre las dos variables de estudio (r = 0.80), así como entre sus dimensiones que componen cada variable.

Abstract: The aim of the following research is to report the results of the widespread application of the Eureka test to achieve its standardization in Chile. This test offers a psychopedagogical tool for the early diagnosis of specific learning difficulties (SLD), considering, on one hand, the Chilean national curriculum, and on the other, the cognitive skills necessary to achieve successful learning outcomes. Within this framework, a quantitative analysis was conducted on 2138 language test renditions and 2254 math test renditions given to students from 1st to 8th grade. In the current scenario, there is a noticeable absence of a contextualized assessment for Chilean students, and even at the Latin American level. The research results show that the Eureka test is an instrument that can diagnose SLD in students from first to eighth grade and assists in establishing intervention strategies that enhance teaching practices, tailored according to the results obtained.

Resumen: El objetivo de la siguiente investigación es dar cuenta de los resultados de la aplicación masiva de la prueba Eureka para lograr su estandarización en Chile. Esta prueba permite contar con un instrumento psicopedagógico para el diagnóstico temprano de Dificultades Específicas del Aprendizaje (DEA) considerando, por un lado, el currículum nacional chileno y por otro, las habilidades cognitivas necesarias para alcanzar niveles de aprendizaje exitosos. En este marco, se realizó un análisis cuantitativo de la aplicación de las 2138 rendiciones de la prueba de lenguaje y a 2254 rendiciones de la prueba de matemáticas a estudiantes desde primero hasta octavo básico. En el escenario actual se detecta la carencia de una evaluación contextualizada para los estudiantes chilenos e incluso a nivel latinoamericano. Los resultados de la investigación arrojan que la prueba Eureka es un instrumento que permite diagnosticar DEA en estudiantes de primero a octavo básico y ayuda a establecer estrategias de intervención que mejoran la práctica docente dirigidas de manera personalizada de acuerdo con los resultados obtenidos.

Resumo: O objetivo da seguinte pesquisa é relatar os resultados da aplicação massiva do teste Eureka para alcançar sua padronização no Chile. Este teste permite-nos ter um instrumento psicopedagógico para o diagnóstico precoce de Dificuldades Específicas de Aprendizagem (DET) considerando, por um lado, o currículo nacional chileno e, por outro, as competências cognitivas necessárias para alcançar níveis de aprendizagem bem sucedidos. Neste contexto, foi realizada uma análise quantitativa da aplicação dos 2.138 desempenhos da prova de linguagem e dos 2.254 desempenhos da prova de matemática a alunos do primeiro ao oitavo ano. No cenário atual, detecta-se a falta de uma avaliação contextualizada para os estudantes chilenos e mesmo em nível latino-americano. Os resultados da pesquisa mostram que o teste Eureka é um instrumento que permite diagnosticar DEA em alunos do primeiro ao oitavo ano e ajuda a estabelecer estratégias de intervenção que melhorem a prática docente direcionada de forma personalizada de acordo com os resultados obtidos.

Resumen: El cultivo de pejerrey, Odontesthes bonariensis (Valenciennes, 1835), desarrollado en Argentina, permite la obtención de huevos y larvas provenientes de reproductores criados en tanques. No obstante, su acuicultura masiva aún no se ha consolidado, entre otras cosas, por el crecimiento lento de la especie. El objetivo de este trabajo es comparar mediante meta-análisis, el crecimiento de O. bonariensis en acuicultura intensiva con el de poblaciones silvestres para conocer en qué medida la especie expresa su potencial en cautiverio. Los datos de longitud estándar por edad, compilados de publicaciones sobre crecimiento en cultivo y en ambientes naturales, fueron ajustados al modelo de crecimiento de von Bertalanffy y convertidos a peso promedio en gramos (W) utilizando la ecuación de peso estándar del pejerrey. Se calcularon los incrementos anuales en W (IW) y la ganancia anual de peso (SAIW) como la diferencia entre los IW en años sucesivos. En el cultivo, el crecimiento en talla y peso por edad se ubicó por encima de la media registrada para los ambientes naturales. Tanto en cultivo como en ambientes naturales, la SAIW presentó valores negativos a partir del tercer año y la máxima ganancia se obtuvo entre el primer y segundo año. Si bien el crecimiento en cautiverio fue superior al de la mayoría de los ambientes considerados, la existencia de valores de tallas superiores por edad en algunas poblaciones silvestres sugiere la posibilidad de alcanzar mejoras en el crecimiento en cultivo.

Abstract: The culture of pejerrey, Odontesthes bonariensis (Valenciennes, 1835), developed in Argentina, allows the obtaining of eggs and larvae from adults reared in tanks. However, its massive aquaculture is still delayed, among other things, by the species slow growth. The aim of this study is to compare, through meta-analysis, the growth of O. bonariensis in intensive aquaculture with that of wild populations to determine the extent this species expresses its potential growth in captivity. Standard length data at age, compilated from publications of in culture and in natural environments, were fitted to the von Bertalanffy growth model and converted to average weight in grams (W) using the standard silverside weight equation. Annual increases in W (IW) and annual weight gain (SAIW) were calculated as the difference between successive IW years. In culture, growth in size and weight per age were above the average recorded among natural environments. Both in cultivation and in natural environments, the SAIW began to present negative values from the third year and the maximum gain was obtained between the first and second year. Although growth in captivity was higher to that in most of the environments considered, the existence of higher size values per age in some wild populations suggest that improvements in growth in culture could potentially be achieved.

RESUMEN La modelación del tiempo y el clima a escala local en las montañas han sido relevantes para el estudio de los ecosistemas agroforestales y su evolución futura. El trabajo tuvo como objetivo integrar un conjunto de datos espaciales de alta resolución al modelo numérico de predicción e investigación meteorológica WRF, adecuado para el análisis meteorológico y del clima local en las montañas de Cuba. En el trabajo, se definió como datos espaciales prioritarios los referidos al relieve, la máscara de tierra como interface océano-suelo, el tipo de cobertura y tipo de suelo. Se seleccionaron las bases de datos espaciales de alta resolución nacionales o globales de mejor calidad y más adecuadas a las características del modelo. Las bases de datos integradas al WRF tuvieron resolución espacial entre 0,95 y 0,03 km aproximadamente en el Ecuador. El incremento y actualización de los datos espaciales robustecieron la capacidad del modelo para el análisis de los factores geográficos formadores del clima local, propiciando mejor desempeño en las montañas. Los resultados de la investigación pudieran contribuir a la vigilancia y pronóstico meteorológico y climático a escala local para las montañas de Cuba. De igual manera, beneficiarían los estudios y gestión de riesgos asociados a incendios forestales, eventos hidrometeorológicos severos, la variabilidad climática, el cambio climático, y otros peligros relacionados con el sistema climático que han afectado los ecosistemas agroforestales cubanos.

RESUMO A modelagem do tempo e do clima em escala local nas montanhas tem sido relevante para o estudo dos ecossistemas agroflorestais e sua evolução futura. O objetivo deste trabalho foi integrar um conjunto de dados espaciais de alta resolução ao modelo numérico de pesquisa e previsão do tempo WRF, adequado para a análise do tempo e do clima local nas montanhas de Cuba. No trabalho, os dados espaciais prioritários foram definidos como aqueles referentes ao relevo, à máscara de terra como uma interface oceano-solo, ao tipo de cobertura e ao tipo de solo. Foram selecionados os bancos de dados espaciais nacionais ou globais de alta resolução da mais alta qualidade e mais adequados às características do modelo. Os bancos de dados integrados ao WRF tinham resolução espacial entre 0,95 e 0,03 km aproximadamente no equador. Os dados espaciais ampliados e atualizados fortaleceram a capacidade do modelo de analisar os fatores geográficos que moldam o clima local, levando a um melhor desempenho nas montanhas. Os resultados da pesquisa podem contribuir para o monitoramento e a previsão do tempo e do clima em escala local nas montanhas de Cuba. Eles também beneficiariam estudos e gerenciamento de riscos associados a incêndios florestais, eventos hidrometeorológicos graves, variabilidade climática, mudanças climáticas e outros perigos relacionados ao sistema climático que afetaram os ecossistemas agroflorestais cubanos.

ABSTRACT Local-scale weather and climate modeling in mountains has been relevant for the study of agroforestry ecosystems and their future evolution. The study aimed to integrate a set of high-resolution spatial data to the WRF numerical meteorological prediction and research model, suitable for meteorological and local climate analysis in the mountains of Cuba. In the study, priority spatial data were defined as those referring to the relief, the land mask as the ocean-soil interface, the type of cover and type of soil. The national or global high-resolution spatial databases of the best quality and most appropriate to the characteristics of the model were selected. The databases integrated into the WRF had spatial resolution between approximately 0.95 and 0.03 km in Ecuador. The increase and updating of spatial data strengthened the model's capacity for the analysis of the geographic factors that shape the local climate, promoting better performance in the mountains. The research results could contribute to meteorological and climate monitoring and forecasting at a local scale for the mountains of Cuba. Likewise, studies and risk management associated with forest fires, severe hydrometeorological events, climate variability, climate change, and other dangers related to the climate system that have affected Cuban agroforestry ecosystems would benefit.

ABSTRACT Purpose: The aim of this study is to perform a high-quality meta-analysis using only randomized controlled trials (RCT) to better define the role of postoperative antibiotics in patients undergoing percutaneous nephrolithotomy (PCNL). Materials and Methods: A literature search for RCTs in EMBASE, PubMed, and Web of Science up to May 2023 was conducted following the PICO framework: Population—adult patients who underwent PCNL; Intervention—postoperative antibiotic prophylaxis until nephrostomy tube withdrawal; Control—single dose of antibiotic during the induction of anesthesia; and Outcome—systemic inflammatory response syndrome (SIRS) or sepsis and fever after PCNL. The protocol was registered on the PROSPERO database (CRD42022361579). We calculated odds ratios (OR) and 95% confidence intervals (CI). A random-effects model was employed, and the alpha risk was defined as < 0.05. Results: Seven articles, encompassing a total of 629 patients, were included in the analysis. The outcome of SIRS or sepsis was extracted from six of the included studies, while the outcome of postoperative fever was extracted from four studies. The analysis revealed no statistical association between the use of postoperative antibiotic prophylaxis until nephrostomy tube withdrawal and the occurrence of SIRS/sepsis (OR 1.236, 95% CI 0.731 – 2.089, p=0.429) or fever (OR 2.049, 95% CI 0.790 – 5.316, p=0.140). Conclusion: Our findings suggest that there is no benefit associated with the use of postoperative antibiotic prophylaxis until nephrostomy tube withdrawal in patients undergoing percutaneous nephrolithotomy (PCNL). We recommend that antibiotic prophylaxis should be administered only until the induction of anesthesia in PCNL. Purpose highquality high quality metaanalysis meta RCT (RCT PCNL . (PCNL) Methods EMBASE PubMed 202 framework Populationadult Population adult Interventionpostoperative Intervention Controlsingle Control single Outcomesystemic Outcome systemic (SIRS CRD42022361579. CRD42022361579 CRD (CRD42022361579) OR 95 CI. (CI) randomeffects random effects employed 005 0 05 0.05 Results articles 62 studies SIRSsepsis 1236 1 236 1.236 0731 731 0.73 2089 2 089 2.089 p=0.429 p0429 p 429 2049 049 2.049 0790 790 0.79 5316 5 316 5.316 p=0.140. p0140 p=0.140 140 p=0.140) Conclusion (PCNL 20 CRD4202236157 (CRD42022361579 9 (CI 00 0.0 6 123 23 1.23 073 73 0.7 208 08 2.08 p=0.42 p042 42 204 04 2.04 079 79 531 31 5.31 p014 p=0.14 14 CRD420223615 (CRD4202236157 0. 12 1.2 07 7 2.0 p=0.4 p04 4 53 3 5.3 p01 p=0.1 CRD42022361 (CRD420223615 1. 2. p=0. p0 5. CRD4202236 (CRD42022361 p=0 CRD420223 (CRD4202236 p= CRD42022 (CRD420223 CRD4202 (CRD42022 CRD420 (CRD4202 CRD42 (CRD420 CRD4 (CRD42 (CRD4 (CRD

RESUMEN Introducción: La enfermedad de Still del adulto es una enfermedad reumática, inflamatoria, sistémica y crónica cuya prevalencia en la población caucásica se estima en 1 caso por cada 100 000 adultos Objetivo: Presentar un paciente adulto joven, con una fiebre de origen desconocido como forma de presentación de la enfermedad de Still del adulto. Caso clínico: Paciente de 29 años de edad con antecedente de fiebre reumática, con un ingreso hospitalario anterior; que presentó un cuadro febril no infeccioso, de 50 días de duración, al cual no se le determinó la causa. Un año después reapareció la fiebre, de similares características, asociada a poliartralgia, hepatoesplenomegalia, anemia, hiperferritinemia, neutrofilia, factor reumatoideo negativo y se constató un cuadro de pericarditis durante el ingreso. Se realizó el diagnóstico de enfermedad de Still del adulto, por exclusión. Se inició tratamiento con esteroides, desapareció la fiebre en las primeras 24 horas y el paciente tuvo una evolución favorable. Conclusiones: La enfermedad de Still del adulto puede presentarse como una fiebre de origen desconocido y se diagnostica por exclusión, ya que no existen manifestaciones clínicas ni pruebas de laboratorio, patognomónicas. La hiperferritinemia es útil para la sospecha diagnóstica.

ABSTRACT Introduction: Adult Still's disease is a rheumatic, inflammatory, systemic and chronic disease whose prevalence in the Caucasian population is estimated at 1 case per 100,000 adults. Objective: To present a young adult patient with a fever of unknown origin as the presentation of adult Still's disease. Clinical case: 29-year-old patient with a history of rheumatic fever, with a previous hospital admission; who presented a non-infectious febrile illness lasting 50 days, for which the cause was not determined. A year later, the fever reappeared, with similar characteristics, associated with polyarthralgia, hepatosplenomegaly, anemia, hyperferritinemia, neutrophilia, negative rheumatoid factor, and pericarditis was noted during admission. The diagnosis of adult Still's disease was made by exclusion. Treatment with steroids was started, the fever disappeared in the first 24 hours and the patient had a favorable evolution. Conclusions: Adult Still's disease can present as a fever of unknown origin and is diagnosed by exclusion, since there are no pathognomonic clinical manifestations or laboratory tests. Hyperferritinemia is useful for diagnostic suspicion.