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Resumen: El Pediatric Index of Mortality 3 (PIM3) es una escala que estima el riesgo de mortalidad en niños ingresados a Unidad de Cuidado Intensivo Pediátrico (UCIP) en la primera hora del ingreso. Objetivo: validar la escala PIM3 en población pediátrica que ingresa a UCIP en alturas sobre los 2.500 metros sobre el nivel del mar (m.s.n.m.), y evaluar si el lactato y el índice Saturación de Oxígeno/Fracción inspirada de oxígeno (SpO2/FiO2) mejoran su capacidad de predicción de mortalidad. Pacientes y Método: Estudio prospectivo multicéntrico realizado en diez UCIP de Colombia entre noviembre de 2016 y junio de 2017. Se recolectaron variables para cálculo del PIM3, lactato sérico y el índice SpO2/FiO2. Se validó su capacidad de discriminación con el área bajo la curva ROC y la calibración mediante la prueba de bondad de ajuste de Hosmer Lemeshow. Resultados: Se incluyeron 2.803 registros de admisiones, con una mortalidad global de 4,8%, y razón estandarizada de mortalidad de 1,1 (IC95%; 1,00-1,3). El PIM3 mostró una baja calibración (p < 0,001) y una adecuada discriminación para la población aplicada (ROC 0,84; IC95% 0,83-0,86). La adición de lactato sérico y SpO2/ FiO2 permitieron una buena calibración (p = 0,75), y mantuvo una alta discriminación de mortalidad (ROC 0,86; IC95% 0,84-0,87). Conclusiones: El comportamiento de la escala PIM3 tiene adecuada discriminación, pero una baja calibración en niños admitidos a UCIP sobre los 2500 m.s.n.m.. Las variables lactato y SpO2/FiO2 mejoraron su habilidad predictiva.

Abstract: The Pediatric Index of Mortality 3 (PIM3) is a scale that estimates the risk of mortality in children admitted to the Pediatric Intensive Care Unit (PICU) within the first hour of admission. Objective: to validate the PIM3 scale in pediatric population admitted to PICU at altitudes over 2,500 meters above sea level (m.a.s.l.), and to evaluate whether lactate and the oxygen saturation/fraction of inspired oxygen (SpO2/FiO2) index improve its ability to predict mortality. Patients and Method: A prospective multicenter study was carried out in 10 PICUs in Colombia between November 2016 and June 2017. Variables were collected for the calculation of PIM3, serum lactate, and SpO2/FiO2 index. Their discrimination capacity was validated with the area under the ROC curve and calibration using the Hosmer Lemeshow goodness-of-fit test. Results: 2,803 admissions were included, with an overall mortality of 4.8% and a standardized mortality ratio of 1.1 (95%CI 1.00-1.3). PIM3 showed low calibration (p < 0.001) and adequate discrimination for the studied population (ROC 0.84; 95%CI 0.83-0.86). The addition of serum lactate and SpO2/FiO2 allowed a good calibration (p = 0.75) and maintained a high discrimination of mortality (ROC 0.86; 95%CI 0.84-0.87). Conclusions: The performance of the PIM3 scale has adequate discrimination, but low calibration in children admitted to PICU at above 2500 m. a. s. l. Lactate and SpO2/FiO2 variables improved its predictive ability.

https://doi.org/10.32641/andespediatr.v94i4.4528

Clostridioides difficile: Characterization of the circulating toxinotypes in an Argentinean public hospital
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Crivaro, Andrea N

; Carasi, Paula

; Salto, Ileana

; Hugo, Ayelen

; Pelichotti, P. Cecilia Soldavini

; Bengoa, Agustina

; Fragomeno, Melisa

; Serradell, María A.

; Minnaard, Jessica

; Rolny, Ivanna

; Alul, Eduardo

; Arregui, Leandro

; Martinez, Macarena E. Fabra

; Valero, Oscar Javier Moreno

; Facente, Andrea

; Magariños, Francisco

; Jewtuchowicz, Virginia

; Pérez, Pablo F.

; Trejo, Fernando M.

Revista argentina de microbiología

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mar 2023, Volume 55 N. 1 Pages 61 - 70

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Clostridioides difficile es un anaerobio esporulado que se asocia con episodios de diarreas hospitalarias. Su virulencia se encuentra vinculada, principalmente, a las toxinas TcdA y TcdB, codificadas por sus respectivos genes, tcdA y tcdB, que son parte de un locus de patogenicidad (PaLoc). Nuestro objetivo fue caracterizar los toxinotipos de C. difficile circulantes en un hospital público. Los genes tcdA y tcdB fueron amplificados y digeridos con diferentes enzimas de restricción: EcoRI para tcdA; HincII y AccI para tcdB. Además, se evaluó la presencia de cdtB (gen de la toxina binaria B) y de las toxinas A y B (por dot blot), así como el efecto citotóxico de sobrenadantes de cultivo sobre células Vero. En conjunto, estos estudios revelaron tres toxinotipos circulantes según la clasificación de Rupnik: 0, I y VIII; el más prevalente fue el último. Aunque son necesarios más estudios (ej., secuenciación), es interesante notar que la presencia del toxinotipo I podría estar relacionada con la introducción de bacterias de diferente origen geográfico. En los pacientes infectados con el toxinotipo VIII, el análisis multivariante de los resultados de laboratorio mostró que los aislamientos asociados a decesos (GCD13, GCD14 y GCD22) estaban situados en regiones de los biplots relacionados con valores de laboratorio alterados al momento de la internación. En los otros pacientes, aunque no se observó correlación entre los valores de laboratorio al momento de la internación y la evolución clínica, los niveles de urea, creatinina y recuento de glóbulos blancos estuvieron correlacionados positivamente entre sí una vez diagnosticada la infección. Nuestro estudio revela la circulación de diferentes toxinotipos de C. difficile en un mismo hospital público. La variedad de toxinotipos puede originarse a partir de microorganismos preexistentes en la región, así como también por la introducción de bacterias provenientes de otras regiones geográficas. La existencia de microorganismos con diferente potencial patogénico es relevante para el control, el seguimiento y el tratamiento de las infecciones.

Abstract Clostridioides difficile is a spore-forming anaerobe microorganism associated to nosocomial diarrhea. Its virulence is mainly associated with TcdA and TcdB toxins, encoded by their respective tcdA and tcdB genes. These genes are part of the pathogenicity locus (PaLoc). Our aim was to characterize relevant C. difficile toxinotypes circulating in the hospital setting. The tcdA and tcdB genes were amplified and digested with different restriction enzymes: EcoRI for tcdA; HincII and AccI for tcdB. In addition, the presence of the cdtB (binary toxin) gene, TcdA and TcdB toxins by dot blot and the cytotoxic effect of culture supernatants on Vero cells, were evaluated. Altogether, these studies revealed three different circulating toxinotypes according to Rupnik's classification: 0, I and VIII, being the latter the most prevalent one. Even though more studies are certainly necessary (e.g. sequencing analysis), it is worth noting that the occurrence of toxinotype I could be related to the introduction of bacteria from different geographical origins. The multivariate analysis conducted on the laboratory values of individuals infected with the most prevalent toxinotype (VIII) showed that the isolates associated with fatal outcomes (GCD13, GCD14 and GCD22) are located in regions of the biplots related to altered laboratory values at admission. In other patients, although laboratory values at admission were not correlated, levels of urea, creatinine and white blood cells were positively correlated after the infection was diagnosed. Our study reveals the circulation of different toxinotypes of C. difficile strains in this public hospital. The variety of toxinotypes can arise from pre-existing microorganisms as well as through the introduction of bacteria from other geographical regions. The existence of microorganisms with different pathogenic potential is relevant for the control, follow-up, and treatment of the infections.

https://doi.org/10.1016/j.ram.2022.05.010

Escala “Pediatric Index Mortality 3” (PIM3) como predictor de mortalidad en unidades de cuidado intensivo pediátrico ubicadas a gran altitud
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López-Barón, Eliana

; Vasquez Hoyos, Pablo

; Martinez-Solarte, Mario

; Godoy, Javier

; Maya, Luis Carlos

; Perdomo Ramírez, Ivan

; Marina Mejía, Luz

; Godoy, Carol

; Pardo, Rosalba

; Roa, Juan David

; Mazzillo, Liliana

; González, Otto

; Fernández-Sarmiento, Jaime

; Izquierdo Borrero, Ledys María

; Duitama Vergara, Lorena

; Reyes, Martha

Andes pediatrica

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2023, N. ahead

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

https://doi.org/10.32641/andespediatr.v94i3.4528

Ultimate capacity prediction of RC and SFRC beams with low shear span-depth ratio using NLFEA and inverse analysis
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Benedetty, Carlos A.

; Irreño, Ingrid R.

; Martinez, Juan J.

; Almeida, Luiz C.

; Trautwein, Leandro M.

; Krahl, Pablo A.

Revista de la construcción

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dec 2022, Volume 21 N. 3 Pages 718 - 736

Abstract: En | Text: En | PDF: En

Abstract: In this study, the capacity and ultimate behavior of Reinforced Concrete (RC) and Steel Fiber Reinforced Concrete (SFRC) beams are evaluated. Nonlinear Finite Element Analysis (NLFEA) and the inverse analysis technique were used to model its structural response using the ATENA finite element software. The smeared crack approach, the crack band model, and advanced constitutive models were used to reproduce concrete fracture. The analyzed beams were subjected to rupture in a four-point bending test setup. The relationship between the shear span and the depth of the beams was 1.5. Four scenarios were analyzed, RC beams with and without stirrups, and SFRC beams without stirrups with volumes of 0.57% and 0.76%. The results obtained in the modeling are discussed in terms of the ability of the models to numerically reproduce the relationships: load versus displacement, load versus strain, crack patterns, and failure modes. The analysis techniques allowed to reproduce the experimental response of the beams with good agreement. They show great potential to solve structural engineering problems.

https://doi.org/10.7764/rdlc.21.3.717

Clinical characteristics and evolution of hematological patients and COVID-19 in Argentina: a report from the Argentine Society of Hematology
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Basquiera, Ana L.

; García, Mercedes J

; Martinez Rolón, Juliana

; Olmedo, Julieta

; Laviano, Julia

; Burgos, Rubén

; Caeiro, Gastón

; Remaggi, Guillermina

; Raña, Pablo

; Paoletti, Mariano

; González, Carlos M.

; Fernández, Isolda

; Pavlovsky, Astrid

; Perusini, Maria A.

; Rodriguez, Andrea

; Guanchiale, Luciana

; Carvani, Analia

; Mandrile, Laura

; Figueroa, Flavia

; Vicente Reparaz, Ángeles

; Fragapane Mathus, Patricia N.

; Garate, Gonzalo

; Fauque, María E.

; Kantor, Gustavo

; Cruset, Soledad

; Gonzalez Lorch, Jacqueline S.

; Szelagowski, Milagros

; Giarini, María P.

; Oliveira, Natalia

; García, María C.

; Ventriglia, María V.

; Pereyra, Patricio H.

; Gutierrez, Daniel R.

; Kusminsky, Gustavo

; Troccoli, Josefina

; Freitas, María J.

; Cranco, Santiago

; Del V.Sanchez, Natalia

; Rey, Irene

; Funes, María E.

; Jarchum, Sol

; Freue, Julian

; Miroli, Augusto

; Guerrero, Osvaldo

; López Ares, Lisa

; Campestri, Reinaldo

; Bove, Victor

; Salinas, Graciela N.

; Cabrejo, María

; Milone, Jorge H.

; Zabaljauregui, Soledad

; Gotta, Daniel

; Dupont, Juan Carlos

; Stemmelin, German

Medicina (Buenos Aires)

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aug 2021, Volume 81 N. 4 Pages 536 - 545

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Individuals with malignancies and COVID-19 have a lower survival compared with the general population. However, the information about the impact of COVID-19 on the whole hematological population is scarce. We aimed to describe the 30th day overall survival (OS) after COVID-19 infection in pa tients with a hematological disease in Argentina. A completely anonymous survey from the Argentine Society of Hematology was delivered to all the hematologists in Argentina; it started in April 2020. A cut-off to analyze the data was performed in December 2020 and, finally, 419 patients were reported and suitable for the analysis (average age: 58 years, 90% with malignant diseases). After the COVID-19 diagnosis, the 30-day OS for the whole population was 80.2%. From the entire group (419), 101 (24.1%) individuals required intensive care unit admission, where the 30-day OS was 46.6%. Among allogeneic stem cell transplant recipients, the 30-day OS was 70.3%. Factors associated with a low OS were two or more comorbidities, an active hematological disease and history of chemotherapy. In individuals with the three factors, the 30-day OS was 49.6% while the 30-day OS in those without those factors was 100%. Patients with hematological diseases have a higher mortality than the general population. This group represents a challenge and requires careful decision-making of the treatment in order not to compromise the chances of cure.

Resumen El presente estudio tuvo por objetivo primario conocer la mortalidad de pacientes con enfermedad hematológica que presentaron infección por COVID-19 en Argentina. Para ello se difundió una encuesta desde la Sociedad Argentina de Hematología (SAH) entre los hematológos para informar sobre los pacientes con enfermedades hematológicas y diagnóstico de infección por SARS- CoV-2, entre el 19/4/2020, y el 7/12/2020. Se incluyeron individuos de todas las edades con diagnóstico de enfermedad hematológica benigna o maligna e infección por SARS-CoV-2 confirmada por técnica de RT-PCR. Se analizaron 419 pacientes (mediana 58 años; 90% enfermedades malignas). La supervivencia al día 30 fue de 80.2%. La supervivencia fue menor en aquellos que requirieron internación (74.2%), cuidados intensivos (46.6%) y asistencia respiratoria mecánica (36.8%). Entre los trasplantados alogénicos la supervivencia fue 70.3%. Los factores vinculados a la supervivencia global fueron las comorbilidades, el estado de la enfermedad al momento de la infección y el antecedente de quimioterapia. Se pudo establecer un score en el que aquellos que tuvieron un puntaje de 4 alcanzaron una supervivencia del 49.6% al día 30, mientras que la de los pacientes con score 0 fue del 100% a 30 días. En comparación con la población general, los pacientes con enfermedades hematológicas presentan una mayor mortalidad vinculada al COVID-19, motivo por el cual es primordial definir pautas destinadas a disminuir la exposición de los mismos sin comprometer las posibilidades de beneficiarse del tratamiento de la enfermedad de base.

121 downloads

Characteristics and Surgical Outcomes in Very Elderly Patients (≥75 years) with Renal Cell Carcinoma: Data from the Latin American Renal Cancer Group
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Garza-Gangemi, Adrián M.

; Castillejos-Molina, Ricardo A.

; Gueglio, Guillermo

; Tobia-Gonzalez, Ignacio P.

; Jurado, Alberto M.

; Meza-Montoya, Luis

; Scorticati, Carlos H.

; Henriques-da-Costa, Walter

; Yandian, Juan

; Ubillos, Luis

; Glina, Sidney

; Tobias-Machado, Marcos

; Rodríguez-Faba, Oscar

; Ameri, Carlos

; Nolazco, Alejandro

; Martinez, Pablo

; Franco Carvalhal, Gustavo

; Bengio, Ruben G.

; Arribillaga, Leandro Cristian

; Langenhin, Raúl

; Muguruza, Diego

; Campos-Salcedo, José G.

; Bravo-Castro, Edgar I.

; Mingote, Pablo A.

; Ginestar, Nicolás

; Autran-Gomez, Ana M.

; Puente, Roberto

; Decia, Ricardo

; Cardoso-Guimarães, Gustavo

; Palou-Redorta, Joan

; Abreu-Clavijo, Diego

; Cassio-Zequi, Stenio de

; Rodriguez-Covarrubias, Francisco T.

Revista de investigación clínica

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oct 2020, Volume 72 N. 5 Pages 308 - 315

Abstract: En | Text: En | PDF: En

Background: The incidence of renal cell carcinoma (RCC) is increasing globally due to an aging population and widespread use of imaging studies. Objective: The aim of this study was to describe the characteristics and perioperative outcomes of RCC surgery in very elderly patients (VEP), ≥ 75 years of age. Methods: This is a retrospective comparative study of 3656 patients who underwent the treatment for RCC from 1990 to 2015 in 28 centers from eight Latin American countries. We compared baseline characteristics as well as clinical and perioperative outcomes according to age groups (<75 vs. ≥75 years). Surgical complications were classified with the Clavien-Dindo score. We performed logistic regression analysis to identify factors associated with perioperative complications. Results: There were 410 VEP patients (11.2%). On bivariate analysis, VEP had a lower body mass index (p < 0.01) and higher ASA score (ASA >2 in 26.3% vs. 12.4%, p < 0.01). There was no difference in performance status and clinical stage between the study groups. There were no differences in surgical margins, estimated blood loss (EBL), complication, and mortality rates (1.3% vs. 0.4%, p = 0.17). On multivariate regression analysis, age ≥75 years (odds ratio [OR] 2.33, p < 0.01), EBL ≥ 500 cc (OR 3.34, p < 0.01), and > pT2 stage (OR 1.63, p = 0.04) were independently associated with perioperative complications. Conclusions: Surgical resection of RCC was safe and successful in VEP. Age ≥75 years was independently associated with 30-day perioperative complications. However, the vast majority were low-grade complications. Age alone should not guide decision-making in these patients, and treatment must be tailored according to performance status and severity of comorbidities. (REV INVEST CLIN. 2020;72(5):308-15)

https://doi.org/10.24875/ric.20000018 141 downloads

Incorporación de estándares bioéticos para la generación de conocimiento científico de calidad en investigación en fauna silvestre: Ciencia con conciencia
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Tadich, Tamara A.

; De Freslón, Inés

; Gallo, Carmen

; Zúñiga, Jesús M.

; Vargas, Ronald

; Torres, Cristian G.

; Tadich, Néstor

; Gimpel, Jessica

; Martinez, Claudio

; Sandoval, Daniel

; Enríquez, Ricardo

; Alfaro, Julio

; Muñoz, Pablo

; Paredes, Rodolfo

; Erranz, Benjamín

; Carvacho, Ingrid

; Mezzano, Marcelo

; Herrera, Emilio A.

Gayana (Concepción)

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jun 2020, Volume 84 N. 1 Pages 68 - 74

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Research using wild animals has diverse aims, such as conservation, environmental management, and the generation of knowledge. The aim of the Institutional Animal Care and Use Committees (IACUCs) is to assure that such research is carried out under high bioethical and animal welfare standards, minimizing animal suffering and environmental impact. This manuscript highlights the relevance of IACUCs as an ally to adjust the procedures on animals to the norm and thus facilitate scientific progress.

RESUMEN La investigación con fauna silvestre tiene diversos propósitos como la conservación de especies, gestión ambiental y generación de conocimiento. El objetivo de los Comités Institucionales de Cuidado y Uso de Animales (CICUAs) es que dicha investigación se realice con altos estándares de bioética y bienestar animal, minimizando el sufrimiento animal y el impacto ambiental. Este artículo destaca la importancia de los CICUAs como un aliado para adecuar los procedimientos con animales a la normativa y facilitar el avance científico.

1109 downloads

2,3,8-Trisubstituted Quinolines with Antimalarial Activity
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MARTINEZ, PABLO D.G.

; KRAKE, SUSANN H.

; POGGI, MAITIA L.

; CAMPBELL, SIMON F.

; WILLIS, PAUL A.

; DIAS, LUIZ C.

Anais da Academia Brasileira de Ciências

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2018, Volume 90 N. 1 Pages 1215 - 1231

Abstract: En | Text: En | PDF: En

ABSTRACT Combination therapy drugs are considered a fundamental way to control malaria as it mimimizes the risk of emergence of resistance to the individual partner drugs. Consequently, this type of therapy constitutes a driving force for the discovery of new drugs with different modes of action, since this will provide options for combining different drugs to achieve the optimum antimalarial treatment. In this context, a 2,3,8-trisubstitued quinoline compound was found in a high throughput screen (HTS) to show an excellent inhibition of P. falciparum NF54 (IC50 = 22 nM) and low cytotoxicity. We performed a detailed evaluation of the substituents to improve the metabolic stability and solubility liabilities of the original hit and identified derivatives with enhanced physicochemical and/or PK properties and that maintained biological activity. However the high potency was not retained on testing against drug resistant plasmodium strains.

https://doi.org/10.1590/0001-3765201820170820 1382 downloads

Trabajos de investigación presentados en el XLIX Congreso Mexicano de Anestesiología: Zacatecas 2015. México
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Sánchez, Claudia

; Osorio-Santiago, María Arelí

; Medina-Tarango, Marco Antonio

; Fernandez De Lara, Alfredo

; Castro-Salinas, Jose Ernesto

; Salazar-Luna, Miguel Angel

; Sanchez, Placido

; Castro-Cayetano, José Esteban

; Millán Hernández, Manuel

; Almonte, Hector Asencion

; Zamora-Aguirre, Salvador A.

; Gudiño, Yocelin Montserrat

; Reyes-Valle, Roberto

; Zepeda-Olivera, Silvia

; Ferretiz-López, Giancarlo

; Salgado, Mónica

; Moctezuma-Ramírez, Luis

; Hernández-Ortiz, Israel Ivan

; Hernández-Zenteno, Norma Angelica

; Martinez, Raquel

; Sánchez-Hernández, Eloy

; Camacho-Gómez, Aldo Constantino

; Martinez, Raquel

; Chenge-Said, Jarumi

; Flores Fonseca, Elvia

; López-Centeno, Martha Alicia

; López, Angélica Yanine

; Jiménez-Ramos, Adriana

; Velasco-Sordo, Luis Ramón

; Hurtado-Reyes, Ignacio Carlos

; Castellanos, Antonio

; Rojas-Peñaloza, Janeth

; Zapién-Madrigal, Jesús Miguel

; Sánchez, Placido

; Sánchez-López, Eric Mauricio

; Mendoza- García, María Isabel

; Calzada-Grijalba, José Francisco

; Hernandez, Israel Ivan

; Castellanos De León, Edgar

; Luna Medina, Cinthya Isabel

; Alvarez-Mora, Lucy Andrea

; López, Angélica Yanine

; Jiménez-Ramos, Adriana

; Velasco-Sordo, Luis Ramón

; Hurtado-Reyes, Ignacio Carlos

; Diaz, Erica Raquel

; Hernandez-Gutierrez, Deoselina

; Gargiulo, Paul Raphael

; Barragán, Maria Jimena

; Ham Mancilla, Ofelia

; Zamora- Gutiérrez, Ana Lilia

; Arteaga, Jaime

; Hernández-Gutierrez, Deoselina

; Ríos-Navarro, Ramón Alejandro

; Romo-Serrano, Erika

; Castellanos, Antonio

; Zapién-Madrigal, Jesús Miguel

; Rojas- Peñaloza, Janeth

; Garduño, Araceli Marselle

; Flores-Rodriguez, Alfonso de Jesus

; Cuervo-Ggonzalez, Alma Kenia

; Puente-Solorio, Armando

; Benitez-Rebollar, Joel Enrique

; Gaona-Valle, Laura Soraya

; Jaime, Mayra Alicia

; Ortega-Suarez, Lizbeth

; Barrientos-Quintanilla, Luis Alberto

; Alvarado-Ramos, Salomon

; Moya-Morales, Yuliana

; Ferretiz, Giancarlo

; César, Julio

; Yañez, Pablo

; Reyes-Valle, Roberto

; Colores-Velazquez, Julio César

; Luna, Arístides De Jesús

; Almonte, Hector Asencion

; Márquez-Noyola, Elizabeth Alicia

; Castellanos, Antonio

; Barrera, Lorena

; Cabrera-Sánchez, Miroslava

; Fernanández-Muñoz, Angel Fernando

; Rolón-Sánchez, Yumara Georgina

; Barragán-Hernández, Adriana Guadalupe

; Lòpez, Estefania

; Osorio-Santiago, Maria Areli

; Muñoz, Beatriz Adelaida

; Cruz-Bautista, Mayra Ivette De La

; Ripoll-Aburto, Carlos Andres

; Ortiz-Maldonado, Jessie Karolina

; Hernández-Rasgado, Javier

; Cuj-Díaz, Alberto

; Sanchez, Placido

; Sarmiento, Lina

; Peña-Olvera, Silvia

; Santiago-Poot, Nohemí

; López, Angélica Yanine

; Jiménez-Ramos, Adriana

; Hurtado-Reyes, Ignacio Carlos

; Ferretiz, Giancarlo

; Pablo-Yañez, Julio César

; Flores-Martinez, Juan Ramón

; Chavez-Contreras, Sara Idali

; Gudiño-Larios, Yocelin Montserrat

; Velazquez, Sara

; Vences-Perez, Noemi Dolores

; Ayala-Bermudez, Celina Alejandra

; Garcia-Castro, Marco Tulio

; Gordillo-Parra, Alejandra

; Barrera, Lorena

; Cabrera-Sánchez, Miroslava

; Martínez-García, Claudia Lizeth

; Zuñiga-Iñiguez, Paloma

; Anaya-Romo, Eduardo

; Antelo-Corral, Jaqueline

; Ramos, Perla Del Carmen

; Hernández-Rasgado, Javier

; Cuj-Díaz, Alberto

; Fonz-Murillo, Elma Patricia

; Cruz-Bautista, Mayra Ivette De la

; Ripoll-Aburto, Carlos Andres

; Cruz, Mayra Ivette De La

; Cuj-Díaz, Alberto

; Hernández-Rasgado, Javier

; Vega-Cano, Miguel

; Ramos-Rodríguez, Perla del Carmen

; Muñoz-Hernández, Beatriz Adelaida

; Caceres, Leonardo Andres

; Arteaga-Favela, Claudia Berenice

; Nava-Osorio, Alejandro

; Arce-Bojorquez, Brisceyda

; Urias, Emma

; Rosario-Ayala, Yuridia Del

; Salazar-Castro, Laura Elena

; Nieblas-Torres, Mariela Lizet

; Arce-Bojorquez, Brisceyda

; Prince-Angulo, Silvia Annel

; Espinoza-Quintero, Erendira

; Alzate, Ana Lizette

; Camacho, Jesus Erick

; Aviles-Lozoya, Jose Trinidad

; Urias, Emma

; Espinoza-Quintero, Erendira

; Castellanos, Antonio

; Cruz, Nora Cecilia

; Rendón-Salazar, Dafne Denisse

; González-Cordero, Gustavo

; Garduño-Chávez, Belia Inés

; Orozco, Arturo Emmanuel

; Guerrero-Morales, Fernando

; Gonzalez-Ortiz, Julio Cesar

; Casillas-Cruz, Angel Alberto

; Aquino-Tamayo, Blanca Olga

; Estrada, Haydeé Lucía

; Soberanes-Alderete, Francisco Javier

; Ojeda-Ramos, Joel

; Martinez-Flores, Carlos

; Sandoval-Rivera, Arturo Guadalupe

; Cáceres-Figeroa, Leonardo Andres

; Ortega, Columba

; Torres-Mata, Lizbeth Yareli

; Peña-Olvera, Silvia

; Huerta, Juana Geraldine

; Sarmiento-Kamar, Rodrigo Ignacio

; Espinoza, Erendira

; Gerardo-Angulo, Alma Ruth

; Nieblas-Torres, Mariela Lizet

; Martinez-Felix, Jesus Israel

; Rochin-Parra, Julia Teresa

; Chavez, Veronica

; Buendía-Roque, Daniel

; Pinales-Aguilar, Guillermina

; Sandoval, Linda Alejandra

; Ovalle-Bueno, Claudia

; Armendáriz-Salinas, Jaime

; Valdovinos, Salvador

; Castellanos, Antonio

; Sandoval, Linda Alejandra

; Medina-Piqué, Sheila

; Aguilar, Hugo

; Barrera, Eduardo

; Márquez, Elizabeth Alicia

; León, Héctor Almonte De

; Castellanos, Antonio

; Rojas-Peñaloza, Janeth

; Zapién-Madrigal, Jesús Miguel

; Paez, Nancy

; Borquez-Torres, Samantha Anabel

; Chinchillas-Chinchillas, Yanira Zelene

; Silva-Romo, Luis Julian

; Aldana, Jorge Pablo

; Hernández-Gutiérrez, Deoselina

; Sánchez-Hernández, Eloy

; Castellanos, Antonio

; Coronel, Berta

; Fuentes-González, Nalleli del Carmen

; Mendoza-García, María Isabel

; Yañez, Gonzalo

; Contreras-Salomón, José Luis

; Garcia-Simbron, Emma

; Chable-Juárez, Randy Josue

; Manriquez-Merino, Ricardo

; Martinez, Raquel

; Chenge-Said, Jarumi

; Hernández Gutiérrez, Deoselina

; Sánchez, Placido

; Arrieta-Ruiz, Marelyn

; González-Velázquez, Felipe

; Estrada-Utrera, Sandra

; Castellanos, Antonio

; Meza, Oscar Eduardo

; Jimenez-Gonzalez, Adriana Guadalupe

; Pilar-Velazquez, Estefania

; Romo-Cortes, Ramona

; Torres-Soto, Maria de la Luz

; Estrada, Maria Sandra

; Espinoza, Cinthia Yadira

; Islas-Ruz, Felix Gilberto

; Perez-Diaz, Roberto

; Manuel-Serna, Roberto Aurelio

; Arce-Bojorquez, Brisceyda

; Medina-Lopez, Francisco de Jesus

; Nieblas-Torres, Mariela Lizet

; Espinoza-Quintero, Erendira

; Ayala-Camargo, Yuridia

; Guadarrama, Hugo

; Flores-Rodriguez, Alfonso de Jesus

; Benitez-Rebollar, Joel Enrique

; Cedillo-Hernandez, Carolina

; Acevedo-Corona, Arturo

; Gaona-Valle, Laura Soraya

; Morfin, Cecilia

; Flores Rodriguez, Alfonso de Jesus

; Cortes-Aceves, Hector Omar

; Rodríguez-Martínez, José Carlos

; Puente Solorio, Armando

; Gaona-Valle, Laura Soraya

; Reyes, Agustin

; Uscanga-Villa, Maria Nieves

; Molina-Rodriguez, Gloria

; Aquino-Tamayo, Blanca Olga

; Cabrera, Francisco

; Motta-Amezquita, Luis Gerardo

; Castellanos-Olivares, Antonio

; Joffre-Mora, Oscar Paul

; Moncada, Adriana Patricia

; Hernandez-Baez, Humberto Trinidad

; Cecilia, Nora

; Garduño-Chávez, Belia Inés

; González-Cordero, Gustavo

; Palacios-Ríos, Dionicio

Anestesia en México

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apr 2016, Volume 28 N. 1 Pages 46 - 96

Abstract: Es | Text: Es | PDF: Es

5425 downloads

10.

Primeros registros de ácaros oribátidos (Acari: Oribatida) de bosques de Nothofagus pumilio en la región Patagónica, Chubut, Argentina
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Ruiz, Erica V.

; Rizzuto, Susana

; Martinez, Pablo A.

Revista de la Sociedad Entomológica Argentina

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jun 2015, Volume 74 N. 1-2 Pages 69 - 73

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Nineteen new records of soil oribatid mites from lenga forest in Chubut, Patagonia Argentina are informed. The new species registered belong to the genera Loftacarus, Liochthonius, Sellnickochthonius, Trichthonius, Austrocarabodes, Maculobates, Tectocepheus, Austroppia, Brachioppiella, Pletzenoppia, Globoppia, Lanceoppia, Membranoppia, Graptoppia, Oppiella, Neoameroppia, Subiasella, Suctobelbella and Pheroliodes. Suctobelbella pseudornatissima and Pheroliodes roblensis are mentioned for the first time from Argentina.

Se informan diecinueve primeros registros de ácaros oribátidos en suelos de bosques de lenga de la provincia de Chubut, Patagonia argentina. Los mismos pertenecen a los géneros Loftacarus, Liochthonius, Sellnickochthonius, Trichthonius, Austrocarabodes, Maculobates, Tectocepheus, Austroppia, Brachioppiella, Pletzenoppia, Globoppia, Lanceoppia, Membranoppia, Graptoppia, Oppiella, Neoameroppia, Subiasella, Suctobelbella y Pheroliodes. Las especies Suctobelbella pseudomatissima y Pheroliodes roblensis se mencionan por primera vez de la Argentina.

267 downloads

11.

Preferential accumulation of sex and Bs chromosomes in biarmed karyotypes by meiotic drive and rates of chromosomal changes in fishes
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MOLINA, WAGNER F.

; MARTINEZ, PABLO A.

; BERTOLLO, LUIZ A.C.

; BIDAU, CLAUDIO J.

Anais da Academia Brasileira de Ciências

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dec 2014, Volume 86 N. 4 Pages 1801 - 1812

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Mecanismos de acúmulo baseados em deriva centromérica típica ou de cromossomos portadores de inversões pericêntricas mostram-se adequados à diferenciação cariotípica mais ampla nas principais ordens de Actinopterygii. Aqui nós mostramos que a deriva meiótica nos peixes é também apoiada pela fixação preferencial de sistemas de cromossomos sexuais e cromossomos B em ordens com cariótipos predominantemente formados por elementos bi-braquiais. O mosaico de tendências cromossômicas que atuam em nível infra-familiar em peixes poderia ser explicado pela interação do processo direcional de deriva meiótica agindo como pano de fundo, modulada em menor escala por fatores adaptativos ou propriedades cariotípicas específicas de cada grupo, conforme proposto pelo modelo de ortoseleção.

Mechanisms of accumulation based on typical centromeric drive or of chromosomes carrying pericentric inversions are adjusted to the general karyotype differentiation in the principal Actinopterygii orders. Here, we show that meiotic drive in fish is also supported by preferential establishment of sex chromosome systems and B chromosomes in orders with predominantly bi-brachial chromosomes. The mosaic of trends acting at an infra-familiar level in fish could be explained as the interaction of the directional process of meiotic drive as background, modulated on a smaller scale by adaptive factors or specific karyotypic properties of each group, as proposed for the orthoselection model.

https://doi.org/10.1590/0001-3765201420130489 2190 downloads

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