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Hepatic endotheliitis in Golden Syrian hamsters (Mesocricetus auratus) experimentally infected with SARS-CoV-2 Mesocricetus auratus SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- SARS-CoV
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Souza, Alex Junior Souza de
; Souza Filho, Antônio Francisco de
; Zimpel, Cristina Kraemer
; Ayupe, Marina Caçador
; Araújo, Marcelo Valdemir de
; Machado, Rafael Rahal Guaragna
; Salles, Erika
; Salgado, Caio Loureiro
; Tavares, Mariana Silva
; Silva-Pereira, Taiana Tainá
; Souza, Paula Carolina de
; Durigon, Edison Luiz
; Heinemann, Marcos Bryan
; Brandão, Paulo Eduardo
; Fonseca, Denise Morais da
; Guimarães, Ana Marcia de Sá
; Sá, Lilian Rose Marques de
.
Revista do Instituto de Medicina Tropical de São Paulo
- Journal Metrics
ABSTRACT Hepatic injuries in COVID-19 are not yet fully understood and indirect pathways (without viral replication in the liver) have been associated with the activation of vascular mechanisms of liver injury in humans infected with SARS-CoV-2. Golden Syrian hamsters are an effective model for experimental reproduction of moderate and self-limiting lung disease during SARS-CoV-2 infection. As observed in humans, this experimental model reproduces lesions of bronchointerstitial pneumonia and pulmonary vascular lesions, including endotheliitis (attachment of lymphoid cells to the luminal surface of endothelium). Extrapulmonary vascular lesions are well documented in COVID-19, but such extrapulmonary vascular lesions have not yet been described in the Golden Syrian hamster model of SARS-CoV-2 infection. The study aimed to evaluate microscopic liver lesions in Golden Syrian hamsters experimentally infected with SARS-CoV-2. In total, 38 conventional Golden Syrian hamsters, divided into infected group (n=24) and mock-infected group (n=14), were euthanized at 2-, 3-, 4-, 5-, 7-, 14-, and 15-days post infection with SARS-CoV-2. Liver fragments were evaluated by histopathology and immunohistochemical detection of SARS-CoV-2 Spike S2 antigens. The frequencies of portal vein endotheliitis, lobular activity, hepatocellular degeneration, and lobular vascular changes were higher among SARS-CoV-2-infected animals. Spike S2 antigen was not detected in liver. The main results indicate that SARS-CoV-2 infection exacerbated vascular and inflammatory lesions in the liver of hamsters with pre-existing hepatitis of unknown origin. A potential application of this animal model in studies of the pathogenesis and evolution of liver lesions associated with SARS-CoV-2 infection still needs further evaluation. COVID19 COVID 19 COVID-1 without SARSCoV2. SARSCoV2 SARSCoV SARS CoV 2. 2 selflimiting self limiting SARS-CoV- attachment endothelium. endothelium . endothelium) COVID19, 19, total 3 n=24 n24 n 24 (n=24 mockinfected mock n=14, n14 n=14 , 14 (n=14) 2, 2- 3, 3- 4, 4 4- 5, 5 5- 7, 7 7- 14, 14- 15days days 15 S antigens activity degeneration SARSCoV2infected SARSCoVinfected animals preexisting pre existing origin evaluation COVID1 1 COVID- SARS-CoV n=2 n2 (n=2 n1 n=1 (n=14 n= (n= (n=1 (n
2.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
; Linzmeier, Adelita M.
; Calor, Adolfo R.
; Garda, Adrian A.
; Kury, Adriano B.
; Fernandes, Agatha C.S.
; Agudo-Padrón, Aisur I.
; Akama, Alberto
; Silva Neto, Alberto M. da
; Burbano, Alejandro L.
; Menezes, Aleksandra
; Pereira-Colavite, Alessandre
; Anichtchenko, Alexander
; Lees, Alexander C.
; Bezerra, Alexandra M.R.
; Domahovski, Alexandre C.
; Pimenta, Alexandre D.
; Aleixo, Alexandre L.P.
; Marceniuk, Alexandre P.
; Paula, Alexandre S. de
; Somavilla, Alexandre
; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
; Santos, Aline B. dos
; Tassi, Aline D.
; Aragão, Allan C.
; Santos, Allan P.M.
; Migotto, Alvaro E.
; Mendes, Amanda C.
; Cunha, Amanda
; Chagas Júnior, Amazonas
; Sousa, Ana A.T. de
; Pavan, Ana C.
; Almeida, Ana C.S.
; Peronti, Ana L.B.G.
; Henriques-Oliveira, Ana L.
; Prudente, Ana L.
; Tourinho, Ana L.
; Pes, Ana M.O.
; Carmignotto, Ana P.
; Wengrat, Ana P.G. da Silva
; Dornellas, Ana P.S.
; Molin, Anamaria Dal
; Puker, Anderson
; Morandini, André C.
; Ferreira, André da S.
; Martins, André L.
; Esteves, André M.
; Fernandes, André S.
; Roza, André S.
; Köhler, Andreas
; Paladini, Andressa
; Andrade, Andrey J. de
; Pinto, Ângelo P.
; Salles, Anna C. de A.
; Gondim, Anne I.
; Amaral, Antonia C.Z.
; Rondón, Antonio A.A.
; Brescovit, Antonio
; Lofego, Antônio C.
; Marques, Antonio C.
; Macedo, Antonio
; Andriolo, Artur
; Henriques, Augusto L.
; Ferreira Júnior, Augusto L.
; Lima, Aurino F. de
; Barros, Ávyla R. de A.
; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
; Santos, Bernardo F.
; Ferraz, Bernardo R.
; Rosa, Brunno B.
; Sampaio, Brunno H.L.
; Bellini, Bruno C.
; Clarkson, Bruno
; Oliveira, Bruno G. de
; Corrêa, Caio C.D.
; Martins, Caleb C.
; Castro-Guedes, Camila F. de
; Souto, Camilla
; Bicho, Carla de L.
; Cunha, Carlo M.
; Barboza, Carlos A. de M.
; Lucena, Carlos A.S. de
; Barreto, Carlos
; Santana, Carlos D.C.M. de
; Agne, Carlos E.Q.
; Mielke, Carlos G.C.
; Caetano, Carlos H.S.
; Flechtmann, Carlos H.W.
; Lamas, Carlos J.E.
; Rocha, Carlos
; Mascarenhas, Carolina S.
; Margaría, Cecilia B.
; Waichert, Cecilia
; Digiani, Celina
; Haddad, Célio F.B.
; Azevedo, Celso O.
; Benetti, Cesar J.
; Santos, Charles M.D. dos
; Bartlett, Charles R.
; Bonvicino, Cibele
; Ribeiro-Costa, Cibele S.
; Santos, Cinthya S.G.
; Justino, Cíntia E.L.
; Canedo, Clarissa
; Bonecker, Claudia C.
; Santos, Cláudia P.
; Carvalho, Claudio J.B. de
; Gonçalves, Clayton C.
; Galvão, Cleber
; Costa, Cleide
; Oliveira, Cléo D.C. de
; Schwertner, Cristiano F.
; Andrade, Cristiano L.
; Pereira, Cristiano M.
; Sampaio, Cristiano
; Dias, Cristina de O.
; Lucena, Daercio A. de A.
; Manfio, Daiara
; Amorim, Dalton de S.
; Queiroz, Dalva L. de
; Queiroz, Dalva L. de
; Colpani, Daniara
; Abbate, Daniel
; Aquino, Daniel A.
; Burckhardt, Daniel
; Cavallari, Daniel C.
; Prado, Daniel de C. Schelesky
; Praciano, Daniel L.
; Basílio, Daniel S.
; Bená, Daniela de C.
; Toledo, Daniela G.P. de
; Takiya, Daniela M.
; Fernandes, Daniell R.R.
; Ament, Danilo C.
; Cordeiro, Danilo P.
; Silva, Darliane E.
; Pollock, Darren A.
; Muniz, David B.
; Gibson, David I.
; Nogueira, David S.
; Marques, Dayse W.A.
; Lucatelli, Débora
; Garcia, Deivys M.A.
; Baêta, Délio
; Ferreira, Denise N.M.
; Rueda-Ramírez, Diana
; Fachin, Diego A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Pádua, Diego G. de
; Barbosa, Diego N.
; Dolibaina, Diego R.
; Amaral, Diogo C.
; Chandler, Donald S.
; Maccagnan, Douglas H.B.
; Caron, Edilson
; Carvalho, Edrielly
; Adriano, Edson A.
; Abreu Júnior, Edson F. de
; Pereira, Edson H.L.
; Viegas, Eduarda F.G.
; Carneiro, Eduardo
; Colley, Eduardo
; Eizirik, Eduardo
; Santos, Eduardo F. dos
; Shimbori, Eduardo M.
; Suárez-Morales, Eduardo
; Arruda, Eliane P. de
; Chiquito, Elisandra A.
; Lima, Élison F.B.
; Castro, Elizeu B. de
; Orlandin, Elton
; Nascimento, Elynton A. do
; Razzolini, Emanuel
; Gama, Emanuel R.R.
; Araujo, Enilma M. de
; Nishiyama, Eric Y.
; Spiessberger, Erich L.
; Santos, Érika C.L. dos
; Contreras, Eugenia F.
; Galati, Eunice A.B.
; Oliveira Junior, Evaldo C. de
; Gallardo, Fabiana
; Hernandes, Fabio A.
; Lansac-Tôha, Fábio A.
; Pitombo, Fabio B.
; Dario, Fabio Di
; Santos, Fábio L. dos
; Mauro, Fabio
; Nascimento, Fabio O. do
; Olmos, Fabio
; Amaral, Fabio R.
; Schunck, Fabio
; Godoi, Fábio S. P. de
; Machado, Fabrizio M.
; Barbo, Fausto E.
; Agrain, Federico A.
; Ribeiro, Felipe B.
; Moreira, Felipe F.F.
; Barbosa, Felipe F.
; Silva, Fenanda S.
; Cavalcanti, Fernanda F.
; Straube, Fernando C.
; Carbayo, Fernando
; Carvalho Filho, Fernando
; Zanella, Fernando C.V.
; Jacinavicius, Fernando de C.
; Farache, Fernando H.A.
; Leivas, Fernando
; Dias, Fernando M.S.
; Mantellato, Fernando
; Vaz-de-Mello, Fernando Z.
; Gudin, Filipe M.
; Albuquerque, Flávio
; Molina, Flavio B.
; Passos, Flávio D.
; Shockley, Floyd W.
; Pinheiro, Francielly F.
; Mello, Francisco de A.G. de
; Nascimento, Francisco E. de L.
; Franco, Francisco L.
; Oliveira, Francisco L. de
; Melo, Francisco T. de V.
; Quijano, Freddy R.B.
; Salles, Frederico F.
; Biffi, Gabriel
; Queiroz, Gabriel C.
; Bizarro, Gabriel L.
; Hrycyna, Gabriela
; Leviski, Gabriela
; Powell, Gareth S.
; Santos, Geane B. dos
; Morse, Geoffrey E.
; Brown, George
; Mattox, George M.T.
; Zimbrão, Geraldo
; Carvalho, Gervásio S.
; Miranda, Gil F.G.
; Moraes, Gilberto J. de
; Lourido, Gilcélia M.
; Neves, Gilmar P.
; Moreira, Gilson R.P.
; Montingelli, Giovanna G.
; Maurício, Giovanni N.
; Marconato, Gláucia
; Lopez, Guilherme E.L.
; Silva, Guilherme L. da
; Muricy, Guilherme
; Brito, Guilherme R.R.
; Garbino, Guilherme S.T.
; Flores, Gustavo E.
; Graciolli, Gustavo
; Libardi, Gustavo S.
; Proctor, Heather C.
; Gil-Santana, Helcio R.
; Varella, Henrique R.
; Escalona, Hermes E.
; Schmitz, Hermes J.
; Rodrigues, Higor D.D.
; Galvão Filho, Hilton de C.
; Quintino, Hingrid Y.S.
; Pinto, Hudson A.
; Rainho, Hugo L.
; Miyahira, Igor C.
; Gonçalves, Igor de S.
; Martins, Inês X.
; Cardoso, Irene A.
; Oliveira, Ismael B. de
; Franz, Ismael
; Fernandes, Itanna O.
; Golfetti, Ivan F.
; S. Campos-Filho, Ivanklin
; Oliveira, Ivo de S.
; Delabie, Jacques H.C.
; Oliveira, Jader de
; Prando, Jadila S.
; Patton, James L.
; Bitencourt, Jamille de A.
; Silva, Janaina M.
; Santos, Jandir C.
; Arruda, Janine O.
; Valderrama, Jefferson S.
; Dalapicolla, Jeronymo
; Oliveira, Jéssica P.
; Hájek, Jiri
; Morselli, João P.
; Narita, João P.
; Martin, João P.I.
; Grazia, Jocélia
; McHugh, Joe
; Cherem, Jorge J.
; Farias Júnior, José A.S.
; Fernandes, Jose A.M.
; Pacheco, José F.
; Birindelli, José L.O.
; Rezende, José M.
; Avendaño, Jose M.
; Duarte, José M. Barbanti
; Ribeiro, José R. Inácio
; Mermudes, José R.M.
; Pujol-Luz, José R.
; Santos, Josenilson R. dos
; Câmara, Josenir T.
; Teixeira, Joyce A.
; Prado, Joyce R. do
; Botero, Juan P.
; Almeida, Julia C.
; Kohler, Julia
; Gonçalves, Julia P.
; Beneti, Julia S.
; Donahue, Julian P.
; Alvim, Juliana
; Almeida, Juliana C.
; Segadilha, Juliana L.
; Wingert, Juliana M.
; Barbosa, Julianna F.
; Ferrer, Juliano
; Santos, Juliano F. dos
; Kuabara, Kamila M.D.
; Nascimento, Karine B.
; Schoeninger, Karine
; Campião, Karla M.
; Soares, Karla
; Zilch, Kássia
; Barão, Kim R.
; Teixeira, Larissa
; Sousa, Laura D. do N.M. de
; Dumas, Leandro L.
; Vieira, Leandro M.
; Azevedo, Leonardo H.G.
; Carvalho, Leonardo S.
; Souza, Leonardo S. de
; Rocha, Leonardo S.G.
; Bernardi, Leopoldo F.O.
; Vieira, Letícia M.
; Johann, Liana
; Salvatierra, Lidianne
; Oliveira, Livia de M.
; Loureiro, Lourdes M.A. El-moor
; Barreto, Luana B.
; Barros, Luana M.
; Lecci, Lucas
; Camargos, Lucas M. de
; Lima, Lucas R.C.
; Almeida, Lucia M.
; Martins, Luciana R.
; Marinoni, Luciane
; Moura, Luciano de A.
; Lima, Luciano
; Naka, Luciano N.
; Miranda, Lucília S.
; Salik, Lucy M.
; Bezerra, Luis E.A.
; Silveira, Luis F.
; Campos, Luiz A.
; Castro, Luiz A.S. de
; Pinho, Luiz C.
; Silveira, Luiz F.L.
; Iniesta, Luiz F.M.
; Tencatt, Luiz F.C.
; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
; Araújo, Marcel S. de
; Monné, Marcela L.
; Labruna, Marcelo B.
; Santis, Marcelo D. de
; Duarte, Marcelo
; Knoff, Marcelo
; Nogueira, Marcelo
; Britto, Marcelo R. de
; Melo, Marcelo R.S. de
; Carvalho, Marcelo R. de
; Tavares, Marcelo T.
; Kitahara, Marcelo V.
; Justo, Marcia C.N.
; Botelho, Marcia J.C.
; Couri, Márcia S.
; Borges-Martins, Márcio
; Felix, Márcio
; Oliveira, Marcio L. de
; Bologna, Marco A.
; Gottschalk, Marco S.
; Tavares, Marcos D.S.
; Lhano, Marcos G.
; Bevilaqua, Marcus
; Santos, Marcus T.T.
; Domingues, Marcus V.
; Sallum, Maria A.M.
; Digiani, María C.
; Santarém, Maria C.A.
; Nascimento, Maria C. do
; Becerril, María de los A.M.
; Santos, Maria E.A. dos
; Passos, Maria I. da S. dos
; Felippe-Bauer, Maria L.
; Cherman, Mariana A.
; Terossi, Mariana
; Bartz, Marie L.C.
; Barbosa, Marina F. de C.
; Loeb, Marina V.
; Cohn-Haft, Mario
; Cupello, Mario
; Martins, Marlúcia B.
; Christofersen, Martin L.
; Bento, Matheus
; Rocha, Matheus dos S.
; Martins, Maurício L.
; Segura, Melissa O.
; Cardenas, Melissa Q.
; Duarte, Mércia E.
; Ivie, Michael A.
; Mincarone, Michael M.
; Borges, Michela
; Monné, Miguel A.
; Casagrande, Mirna M.
; Fernandez, Monica A.
; Piovesan, Mônica
; Menezes, Naércio A.
; Benaim, Natalia P.
; Reategui, Natália S.
; Pedro, Natan C.
; Pecly, Nathalia H.
; Ferreira Júnior, Nelson
; Silva Júnior, Nelson J. da
; Perioto, Nelson W.
; Hamada, Neusa
; Degallier, Nicolas
; Chao, Ning L.
; Ferla, Noeli J.
; Mielke, Olaf H.H.
; Evangelista, Olivia
; Shibatta, Oscar A.
; Oliveira, Otto M.P.
; Albornoz, Pablo C.L.
; Dellapé, Pablo M.
; Gonçalves, Pablo R.
; Shimabukuro, Paloma H.F.
; Grossi, Paschoal
; Rodrigues, Patrícia E. da S.
; Lima, Patricia O.V.
; Velazco, Paul
; Santos, Paula B. dos
; Araújo, Paula B.
; Silva, Paula K.R.
; Riccardi, Paula R.
; Garcia, Paulo C. de A.
; Passos, Paulo G.H.
; Corgosinho, Paulo H.C.
; Lucinda, Paulo
; Costa, Paulo M.S.
; Alves, Paulo P.
; Roth, Paulo R. de O.
; Coelho, Paulo R.S.
; Duarte, Paulo R.M.
; Carvalho, Pedro F. de
; Gnaspini, Pedro
; Souza-Dias, Pedro G.B.
; Linardi, Pedro M.
; Bartholomay, Pedro R.
; Demite, Peterson R.
; Bulirsch, Petr
; Boll, Piter K.
; Pereira, Rachel M.M.
; Silva, Rafael A.P.F.
; Moura, Rafael B. de
; Boldrini, Rafael
; Silva, Rafaela A. da
; Falaschi, Rafaela L.
; Cordeiro, Ralf T.S.
; Mello, Ramon J.C.L.
; Singer, Randal A.
; Querino, Ranyse B.
; Heleodoro, Raphael A.
; Castilho, Raphael de C.
; Constantino, Reginaldo
; Guedes, Reinaldo C.
; Carrenho, Renan
; Gomes, Renata S.
; Gregorin, Renato
; Machado, Renato J.P.
; Bérnils, Renato S.
; Capellari, Renato S.
; Silva, Ricardo B.
; Kawada, Ricardo
; Dias, Ricardo M.
; Siewert, Ricardo
; Brugnera, Ricaro
; Leschen, Richard A.B.
; Constantin, Robert
; Robbins, Robert
; Pinto, Roberta R.
; Reis, Roberto E. dos
; Ramos, Robson T. da C.
; Cavichioli, Rodney R.
; Barros, Rodolfo C. de
; Caires, Rodrigo A.
; Salvador, Rodrigo B.
; Marques, Rodrigo C.
; Araújo, Rodrigo C.
; Araujo, Rodrigo de O.
; Dios, Rodrigo de V.P.
; Johnsson, Rodrigo
; Feitosa, Rodrigo M.
; Hutchings, Roger W.
; Lara, Rogéria I.R.
; Rossi, Rogério V.
; Gerstmeier, Roland
; Ochoa, Ronald
; Hutchings, Rosa S.G.
; Ale-Rocha, Rosaly
; Rocha, Rosana M. da
; Tidon, Rosana
; Brito, Rosangela
; Pellens, Roseli
; Santos, Sabrina R. dos
; Santos, Sandra D. dos
; Paiva, Sandra V.
; Santos, Sandro
; Oliveira, Sarah S. de
; Costa, Sávio C.
; Gardner, Scott L.
; Leal, Sebastián A. Muñoz
; Aloquio, Sergio
; Bonecker, Sergio L.C.
; Bueno, Sergio L. de S.
; Almeida, Sérgio M. de
; Stampar, Sérgio N.
; Andena, Sérgio R.
; Posso, Sergio R.
; Lima, Sheila P.
; Gadelha, Sian de S.
; Thiengo, Silvana C.
; Cohen, Simone C.
; Brandão, Simone N.
; Rosa, Simone P.
; Ribeiro, Síria L.B.
; Letana, Sócrates D.
; Santos, Sonia B. dos
; Andrade, Sonia C.S.
; Dávila, Stephane
; Vaz, Stéphanie
; Peck, Stewart B.
; Christo, Susete W.
; Cunha, Suzan B.Z.
; Gomes, Suzete R.
; Duarte, Tácio
; Madeira-Ott, Taís
; Marques, Taísa
; Roell, Talita
; Lima, Tarcilla C. de
; Sepulveda, Tatiana A.
; Maria, Tatiana F.
; Ruschel, Tatiana P.
; Rodrigues, Thaiana
; Marinho, Thais A.
; Almeida, Thaís M. de
; Miranda, Thaís P.
; Freitas, Thales R.O.
; Pereira, Thalles P.L.
; Zacca, Thamara
; Pacheco, Thaynara L.
; Martins, Thiago F.
; Alvarenga, Thiago M.
; Carvalho, Thiago R. de
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Henry, Thomas
; Pikart, Tiago G.
; Porto, Tiago J.
; Krolow, Tiago K.
; Carvalho, Tiago P.
; Lotufo, Tito M. da C.
; Caramaschi, Ulisses
; Pinheiro, Ulisses dos S.
; Pardiñas, Ulyses F.J.
; Maia, Valéria C.
; Tavares, Valeria
; Costa, Valmir A.
; Amaral, Vanessa S. do
; Silva, Vera C.
; Wolff, Vera R. dos S.
; Slobodian, Verônica
; Silva, Vinícius B. da
; Espíndola, Vinicius C.
; Costa-Silva, Vinicius da
; Bertaco, Vinicius de A.
; Padula, Vinícius
; Ferreira, Vinicius S.
; Silva, Vitor C.P. da
; Piacentini, Vítor de Q.
; Sandoval-Gómez, Vivian E.
; Trevine, Vivian
; Sousa, Viviane R.
; Sant’Anna, Vivianne B. de
; Mathis, Wayne N.
; Souza, Wesley de O.
; Colombo, Wesley D.
; Tomaszewska, Wioletta
; Wosiacki, Wolmar B.
; Ovando, Ximena M.C.
; Leite, Yuri L.R.
.
ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
3.
Incidence of prematurity and associated risk factors among users of a health insurance company
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Resumo Objetivos: analisar a incidência de prematuridade em usuárias de uma operadora de planos de saúde; analisar os fatores de risco associados. Métodos: estudo retrospectivo, realizado em cinco maternidades com puérperas usuárias de planos de saúde por meio de entrevistas telefônicas guiadas por questionário semiestruturado. As variáveis estudadas foram relativas às condições sociodemográficas, clínicas e de desfecho. Realizou-se análise uni e multivariada com regressão logística Backward. Resultados: foram avaliadas 1193 participantes e identificados 116 nascimentos prematuros. Verificou-se que prematuro prévio (p<0,001; OR=4,596; IC95%=2,544-8,305), oligodrâmnio (p=0,019; OR=2,697; IC95%=1,140-6,380), diabetes mellitus anterior a gestação (p<0,001; OR=4,897; IC95%=2,147-11,169), gestação de gemelares (p<0,001; OR=7,115; IC95%=3,578-14,148), doença autoimune (p<0,001; OR=3,799; C95%=1,987-7,260), estresse durante a gestação (p=0,026; OR=1,568; IC95%=1,053-2,335), infecção urinária (p=0,008; OR=1,825; IC95%=1,161-2,867), placenta prévia (p=0,001; OR=3,180; IC95%=1,517-6,667), pré-eclâmpsia (p<0,001; OR=4,833; IC95%=2,860-8,169), sangramento gestacional (p=0,001; OR=2,185; IC95%=1,340-3,564), intervalo entre gestações menor que seis meses (p=0,001; OR=3,502; IC95%=1,594-7,698), gestação proveniente de fertilização in vitro (p<0,001; OR=2,874; IC95%=1,466-5,637) foram estatisticamente relevantes como fatores de risco para prematuridade. Conclusão: o conhecimento desses fatores pode ser importante na elaboração de estratégias para melhorar a assistência ofertada às gestantes por operadoras de planos de saúde. Objetivos associados Métodos retrospectivo semiestruturado sociodemográficas desfecho Realizouse Realizou se Backward Resultados 119 11 prematuros Verificouse Verificou p<0,001 p0001 p 0 001 (p<0,001 OR=4,596 OR4596 OR 4 596 IC95%=2,5448,305, IC9525448305 IC IC95%=2,544 8,305 , IC95 2 544 8 305 IC95%=2,544-8,305) p=0,019 p0019 019 (p=0,019 OR=2,697 OR2697 697 IC95%=1,1406,380, IC9511406380 IC95%=1,140 6,380 1 140 6 380 IC95%=1,140-6,380) OR=4,897 OR4897 897 IC95%=2,14711,169, IC95214711169 IC95%=2,147 11,169 147 169 IC95%=2,147-11,169) OR=7,115 OR7115 7 115 IC95%=3,57814,148, IC95357814148 IC95%=3,578 14,148 3 578 14 148 IC95%=3,578-14,148) OR=3,799 OR3799 799 C95%=1,9877,260, C9519877260 C C95%=1,987 7,260 C95 987 260 C95%=1,987-7,260) p=0,026 p0026 026 (p=0,026 OR=1,568 OR1568 568 IC95%=1,0532,335, IC9510532335 IC95%=1,053 2,335 053 335 IC95%=1,053-2,335) p=0,008 p0008 008 (p=0,008 OR=1,825 OR1825 825 IC95%=1,1612,867, IC9511612867 IC95%=1,161 2,867 161 867 IC95%=1,161-2,867) p=0,001 (p=0,001 OR=3,180 OR3180 180 IC95%=1,5176,667, IC9515176667 IC95%=1,517 6,667 517 667 IC95%=1,517-6,667) préeclâmpsia pré eclâmpsia OR=4,833 OR4833 833 IC95%=2,8608,169, IC9528608169 IC95%=2,860 8,169 860 IC95%=2,860-8,169) OR=2,185 OR2185 185 IC95%=1,3403,564, IC9513403564 IC95%=1,340 3,564 340 564 IC95%=1,340-3,564) OR=3,502 OR3502 502 IC95%=1,5947,698, IC9515947698 IC95%=1,594 7,698 594 698 IC95%=1,594-7,698) OR=2,874 OR2874 874 IC95%=1,4665,637 IC9514665637 IC95%=1,466 5,637 466 5 637 IC95%=1,466-5,637 Conclusão p<0,00 p000 00 (p<0,00 OR=4,59 OR459 59 5448 IC95%=2,5448,305 IC952544830 IC952544 IC95%=2,54 8305 8,30 IC9 54 30 IC95%=2,544-8,305 p=0,01 p001 01 (p=0,01 OR=2,69 OR269 69 1406 IC95%=1,1406,380 IC951140638 IC951140 IC95%=1,14 6380 6,38 38 IC95%=1,140-6,380 OR=4,89 OR489 89 14711 IC95%=2,14711,169 IC9521471116 IC952147 IC95%=2,14 11169 11,16 16 IC95%=2,147-11,169 OR=7,11 OR711 57814 IC95%=3,57814,148 IC9535781414 IC953578 IC95%=3,57 14148 14,14 57 IC95%=3,578-14,148 OR=3,79 OR379 79 9877 C95%=1,9877,260 C951987726 C951987 C95%=1,98 7260 7,26 C9 98 26 C95%=1,987-7,260 p=0,02 p002 02 (p=0,02 OR=1,56 OR156 56 0532 IC95%=1,0532,335 IC951053233 IC951053 IC95%=1,05 2335 2,33 05 33 IC95%=1,053-2,335 p=0,00 (p=0,00 OR=1,82 OR182 82 1612 IC95%=1,1612,867 IC951161286 IC951161 IC95%=1,16 2867 2,86 86 IC95%=1,161-2,867 OR=3,18 OR318 18 5176 IC95%=1,5176,667 IC951517666 IC951517 IC95%=1,51 6667 6,66 51 66 IC95%=1,517-6,667 OR=4,83 OR483 83 8608 IC95%=2,8608,169 IC952860816 IC952860 IC95%=2,86 8169 8,16 IC95%=2,860-8,169 OR=2,18 OR218 3403 IC95%=1,3403,564 IC951340356 IC951340 IC95%=1,34 3564 3,56 34 IC95%=1,340-3,564 OR=3,50 OR350 50 5947 IC95%=1,5947,698 IC951594769 IC951594 IC95%=1,59 7698 7,69 IC95%=1,594-7,698 OR=2,87 OR287 87 4665 IC95%=1,4665,63 IC951466563 IC951466 IC95%=1,46 5637 5,63 46 63 IC95%=1,466-5,63 p<0,0 p00 (p<0,0 OR=4,5 OR45 IC95%=2,5448,30 IC95254483 IC95254 IC95%=2,5 830 8,3 IC95%=2,544-8,30 p=0,0 (p=0,0 OR=2,6 OR26 IC95%=1,1406,38 IC95114063 IC95114 IC95%=1,1 638 6,3 IC95%=1,140-6,38 OR=4,8 OR48 1471 IC95%=2,14711,16 IC952147111 IC95214 IC95%=2,1 1116 11,1 IC95%=2,147-11,16 OR=7,1 OR71 5781 IC95%=3,57814,14 IC953578141 IC95357 IC95%=3,5 1414 14,1 IC95%=3,578-14,14 OR=3,7 OR37 C95%=1,9877,26 C95198772 C95198 C95%=1,9 726 7,2 9 C95%=1,987-7,26 OR=1,5 OR15 IC95%=1,0532,33 IC95105323 IC95105 IC95%=1,0 233 2,3 IC95%=1,053-2,33 OR=1,8 OR18 IC95%=1,1612,86 IC95116128 IC95116 286 2,8 IC95%=1,161-2,86 OR=3,1 OR31 IC95%=1,5176,66 IC95151766 IC95151 IC95%=1,5 666 6,6 IC95%=1,517-6,66 IC95%=2,8608,16 IC95286081 IC95286 IC95%=2,8 816 8,1 IC95%=2,860-8,16 OR=2,1 OR21 IC95%=1,3403,56 IC95134035 IC95134 IC95%=1,3 356 3,5 IC95%=1,340-3,56 OR=3,5 OR35 IC95%=1,5947,69 IC95159476 IC95159 769 7,6 IC95%=1,594-7,69 OR=2,8 OR28 IC95%=1,4665,6 IC95146656 IC95146 IC95%=1,4 563 5,6 IC95%=1,466-5,6 p<0, p0 (p<0, OR=4, OR4 IC95%=2,5448,3 IC9525448 IC9525 IC95%=2, 8, IC95%=2,544-8,3 p=0, (p=0, OR=2, OR2 IC95%=1,1406,3 IC9511406 IC9511 IC95%=1, 6, IC95%=1,140-6,3 IC95%=2,14711,1 IC95214711 IC9521 111 11, IC95%=2,147-11,1 OR=7, OR7 IC95%=3,57814,1 IC95357814 IC9535 IC95%=3, 141 14, IC95%=3,578-14,1 OR=3, OR3 C95%=1,9877,2 C9519877 C9519 C95%=1, 72 7, C95%=1,987-7,2 OR=1, OR1 IC95%=1,0532,3 IC9510532 IC9510 23 2, IC95%=1,053-2,3 IC95%=1,1612,8 IC9511612 28 IC95%=1,161-2,8 IC95%=1,5176,6 IC9515176 IC9515 IC95%=1,517-6,6 IC95%=2,8608,1 IC9528608 IC9528 81 IC95%=2,860-8,1 IC95%=1,3403,5 IC9513403 IC9513 35 3, IC95%=1,340-3,5 IC95%=1,5947,6 IC9515947 76 IC95%=1,594-7,6 IC95%=1,4665, IC9514665 IC9514 5, IC95%=1,466-5, p<0 (p<0 OR=4 IC95%=2,5448, IC952 IC95%=2 IC95%=2,544-8, p=0 (p=0 OR=2 IC95%=1,1406, IC951 IC95%=1 IC95%=1,140-6, IC95%=2,14711, IC9521471 IC95%=2,147-11, OR=7 IC95%=3,57814, IC9535781 IC953 IC95%=3 IC95%=3,578-14, OR=3 C95%=1,9877, C951 C95%=1 C95%=1,987-7, OR=1 IC95%=1,0532, IC95%=1,053-2, IC95%=1,1612, IC95%=1,161-2, IC95%=1,5176, IC95%=1,517-6, IC95%=2,8608, IC95%=2,860-8, IC95%=1,3403, IC95%=1,340-3, IC95%=1,5947, IC95%=1,594-7, IC95%=1,4665 IC95%=1,466-5 p< (p< OR= IC95%=2,5448 IC95%= IC95%=2,544-8 p= (p= IC95%=1,1406 IC95%=1,140-6 IC95%=2,14711 IC95%=2,147-11 IC95%=3,57814 IC95%=3,578-14 C95%=1,9877 C95%= C95%=1,987-7 IC95%=1,0532 IC95%=1,053-2 IC95%=1,1612 IC95%=1,161-2 IC95%=1,5176 IC95%=1,517-6 IC95%=2,8608 IC95%=2,860-8 IC95%=1,3403 IC95%=1,340-3 IC95%=1,5947 IC95%=1,594-7 IC95%=1,466- (p IC95% IC95%=2,544- IC95%=1,140- IC95%=2,1471 IC95%=2,147-1 IC95%=3,5781 IC95%=3,578-1 C95% C95%=1,987- IC95%=1,053- IC95%=1,161- IC95%=1,517- IC95%=2,860- IC95%=1,340- IC95%=1,594- IC95%=2,147- IC95%=3,578-
Abstract Objectives: to analyze the incidence ofprematurity in users of a health insurance plan; to analyze the associated risk factors. Methods: a retrospective study was conducted in five maternity hospitals with puerperal women who were users of health insurance plans by telephone interviews guided by a semi-structured questionnaire. The variables studied were related to sociodemographic, clinical and outcome conditions. Univariate and multivariate analysis with Backward logistic regression was performed. Results: 1,193 participants were evaluated and 116 premature births were identified. It was found that preterm birth (p<0.001; OR=4.596; CI95%=2.544-8.305), oligohydramnios (p=0.019; OR=2.697; CI95% =1.140-6.380), diabetes mellitus prior to pregnancy (p<0.001; OR=4.897; CI95%=2.147-11.169), twin pregnancy (p<0.001; OR=7.115; CI95%=3.578-14.148), autoimmune disease (p<0.001; OR=3.799; CI95%=1.987-7.260), stress during pregnancy (p=0.026; OR=1.568; CI95%=1.053-2.335), urinary infection (p=0.008; OR=1.825; CI95%=1.161-2.867), placenta previa (p=0.001; OR=3.180; CI95%=1.517-6.667), pre-eclampsia (p<0.001; OR=4.833; CI95%=2.860-8.169), gestational bleeding (p=0.001; OR=2.185; CI95%=1.340-3.564), interval between pregnancies less than six months (p=0.001; OR=3.502; CI95%=1.594-7.698), pregnancy resulting from in vitro fertilization (p<0.001; OR=2.874; CI95%=1.466-5.637) were statistically relevant as risk factors for prematurity. Conclusion: knowledge of these factors may be important in developing strategies to improve the assistance offered to pregnant women by the health insurance providers. Objectives plan Methods semistructured semi structured questionnaire sociodemographic conditions performed Results 1193 1 193 1,19 11 identified p<0.001 p0001 p 0 001 (p<0.001 OR=4.596 OR4596 OR 4 596 CI95%=2.5448.305, CI9525448305 CI CI95%=2.544 8.305 , CI95 2 544 8 305 CI95%=2.544-8.305) p=0.019 p0019 019 (p=0.019 OR=2.697 OR2697 697 =1.1406.380, 11406380 =1.140 6.380 140 6 380 =1.140-6.380) OR=4.897 OR4897 897 CI95%=2.14711.169, CI95214711169 CI95%=2.147 11.169 147 169 CI95%=2.147-11.169) OR=7.115 OR7115 7 115 CI95%=3.57814.148, CI95357814148 CI95%=3.578 14.148 3 578 14 148 CI95%=3.578-14.148) OR=3.799 OR3799 799 CI95%=1.9877.260, CI9519877260 CI95%=1.987 7.260 987 260 CI95%=1.987-7.260) p=0.026 p0026 026 (p=0.026 OR=1.568 OR1568 568 CI95%=1.0532.335, CI9510532335 CI95%=1.053 2.335 053 335 CI95%=1.053-2.335) p=0.008 p0008 008 (p=0.008 OR=1.825 OR1825 825 CI95%=1.1612.867, CI9511612867 CI95%=1.161 2.867 161 867 CI95%=1.161-2.867) p=0.001 (p=0.001 OR=3.180 OR3180 180 CI95%=1.5176.667, CI9515176667 CI95%=1.517 6.667 517 667 CI95%=1.517-6.667) preeclampsia pre eclampsia OR=4.833 OR4833 833 CI95%=2.8608.169, CI9528608169 CI95%=2.860 8.169 860 CI95%=2.860-8.169) OR=2.185 OR2185 185 CI95%=1.3403.564, CI9513403564 CI95%=1.340 3.564 340 564 CI95%=1.340-3.564) OR=3.502 OR3502 502 CI95%=1.5947.698, CI9515947698 CI95%=1.594 7.698 594 698 CI95%=1.594-7.698) OR=2.874 OR2874 874 CI95%=1.4665.637 CI9514665637 CI95%=1.466 5.637 466 5 637 CI95%=1.466-5.637 prematurity Conclusion providers 119 19 1,1 p<0.00 p000 00 (p<0.00 OR=4.59 OR459 59 5448 CI95%=2.5448.305 CI952544830 CI952544 CI95%=2.54 8305 8.30 CI9 54 30 CI95%=2.544-8.305 p=0.01 p001 01 (p=0.01 OR=2.69 OR269 69 1406 =1.1406.380 1140638 1140 =1.14 6380 6.38 38 =1.140-6.380 OR=4.89 OR489 89 14711 CI95%=2.14711.169 CI9521471116 CI952147 CI95%=2.14 11169 11.16 16 CI95%=2.147-11.169 OR=7.11 OR711 57814 CI95%=3.57814.148 CI9535781414 CI953578 CI95%=3.57 14148 14.14 57 CI95%=3.578-14.148 OR=3.79 OR379 79 9877 CI95%=1.9877.260 CI951987726 CI951987 CI95%=1.98 7260 7.26 98 26 CI95%=1.987-7.260 p=0.02 p002 02 (p=0.02 OR=1.56 OR156 56 0532 CI95%=1.0532.335 CI951053233 CI951053 CI95%=1.05 2335 2.33 05 33 CI95%=1.053-2.335 p=0.00 (p=0.00 OR=1.82 OR182 82 1612 CI95%=1.1612.867 CI951161286 CI951161 CI95%=1.16 2867 2.86 86 CI95%=1.161-2.867 OR=3.18 OR318 18 5176 CI95%=1.5176.667 CI951517666 CI951517 CI95%=1.51 6667 6.66 51 66 CI95%=1.517-6.667 OR=4.83 OR483 83 8608 CI95%=2.8608.169 CI952860816 CI952860 CI95%=2.86 8169 8.16 CI95%=2.860-8.169 OR=2.18 OR218 3403 CI95%=1.3403.564 CI951340356 CI951340 CI95%=1.34 3564 3.56 34 CI95%=1.340-3.564 OR=3.50 OR350 50 5947 CI95%=1.5947.698 CI951594769 CI951594 CI95%=1.59 7698 7.69 CI95%=1.594-7.698 OR=2.87 OR287 87 4665 CI95%=1.4665.63 CI951466563 CI951466 CI95%=1.46 5637 5.63 46 63 CI95%=1.466-5.63 1, p<0.0 p00 (p<0.0 OR=4.5 OR45 CI95%=2.5448.30 CI95254483 CI95254 CI95%=2.5 830 8.3 CI95%=2.544-8.30 p=0.0 (p=0.0 OR=2.6 OR26 =1.1406.38 114063 114 =1.1 638 6.3 =1.140-6.38 OR=4.8 OR48 1471 CI95%=2.14711.16 CI952147111 CI95214 CI95%=2.1 1116 11.1 CI95%=2.147-11.16 OR=7.1 OR71 5781 CI95%=3.57814.14 CI953578141 CI95357 CI95%=3.5 1414 14.1 CI95%=3.578-14.14 OR=3.7 OR37 CI95%=1.9877.26 CI95198772 CI95198 CI95%=1.9 726 7.2 9 CI95%=1.987-7.26 OR=1.5 OR15 CI95%=1.0532.33 CI95105323 CI95105 CI95%=1.0 233 2.3 CI95%=1.053-2.33 OR=1.8 OR18 CI95%=1.1612.86 CI95116128 CI95116 CI95%=1.1 286 2.8 CI95%=1.161-2.86 OR=3.1 OR31 CI95%=1.5176.66 CI95151766 CI95151 CI95%=1.5 666 6.6 CI95%=1.517-6.66 CI95%=2.8608.16 CI95286081 CI95286 CI95%=2.8 816 8.1 CI95%=2.860-8.16 OR=2.1 OR21 CI95%=1.3403.56 CI95134035 CI95134 CI95%=1.3 356 3.5 CI95%=1.340-3.56 OR=3.5 OR35 CI95%=1.5947.69 CI95159476 CI95159 769 7.6 CI95%=1.594-7.69 OR=2.8 OR28 CI95%=1.4665.6 CI95146656 CI95146 CI95%=1.4 563 5.6 CI95%=1.466-5.6 p<0. p0 (p<0. OR=4. OR4 CI95%=2.5448.3 CI9525448 CI9525 CI95%=2. 8. CI95%=2.544-8.3 p=0. (p=0. OR=2. OR2 =1.1406.3 11406 =1. 6. =1.140-6.3 CI95%=2.14711.1 CI95214711 CI9521 111 11. CI95%=2.147-11.1 OR=7. OR7 CI95%=3.57814.1 CI95357814 CI9535 CI95%=3. 141 14. CI95%=3.578-14.1 OR=3. OR3 CI95%=1.9877.2 CI9519877 CI9519 CI95%=1. 72 7. CI95%=1.987-7.2 OR=1. OR1 CI95%=1.0532.3 CI9510532 CI9510 23 2. CI95%=1.053-2.3 CI95%=1.1612.8 CI9511612 CI9511 28 CI95%=1.161-2.8 CI95%=1.5176.6 CI9515176 CI9515 CI95%=1.517-6.6 CI95%=2.8608.1 CI9528608 CI9528 81 CI95%=2.860-8.1 CI95%=1.3403.5 CI9513403 CI9513 35 3. CI95%=1.340-3.5 CI95%=1.5947.6 CI9515947 76 CI95%=1.594-7.6 CI95%=1.4665. CI9514665 CI9514 5. CI95%=1.466-5. p<0 (p<0 OR=4 CI95%=2.5448. CI952 CI95%=2 CI95%=2.544-8. p=0 (p=0 OR=2 =1.1406. =1 =1.140-6. CI95%=2.14711. CI9521471 CI95%=2.147-11. OR=7 CI95%=3.57814. CI9535781 CI953 CI95%=3 CI95%=3.578-14. OR=3 CI95%=1.9877. CI951 CI95%=1 CI95%=1.987-7. OR=1 CI95%=1.0532. CI95%=1.053-2. CI95%=1.1612. CI95%=1.161-2. CI95%=1.5176. CI95%=1.517-6. CI95%=2.8608. CI95%=2.860-8. CI95%=1.3403. CI95%=1.340-3. CI95%=1.5947. CI95%=1.594-7. CI95%=1.4665 CI95%=1.466-5 p< (p< OR= CI95%=2.5448 CI95%= CI95%=2.544-8 p= (p= =1.1406 = =1.140-6 CI95%=2.14711 CI95%=2.147-11 CI95%=3.57814 CI95%=3.578-14 CI95%=1.9877 CI95%=1.987-7 CI95%=1.0532 CI95%=1.053-2 CI95%=1.1612 CI95%=1.161-2 CI95%=1.5176 CI95%=1.517-6 CI95%=2.8608 CI95%=2.860-8 CI95%=1.3403 CI95%=1.340-3 CI95%=1.5947 CI95%=1.594-7 CI95%=1.466- (p CI95%=2.544- =1.140- CI95%=2.1471 CI95%=2.147-1 CI95%=3.5781 CI95%=3.578-1 CI95%=1.987- CI95%=1.053- CI95%=1.161- CI95%=1.517- CI95%=2.860- CI95%=1.340- CI95%=1.594- CI95%=2.147- CI95%=3.578-
4.
Sexual effects and long-term outcomes of endoscopic lumbar sympathectomy for plantar hyperhidrosis in men: a cross-sectional study longterm long term men crosssectional cross sectional
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Loureiro, Marcelo de Paula
; Novais, Pietro Maran
; Coelho, Ruimário Machado
; Paulin, João Augusto Nocera
.
Resumo Contexto A hiperidrose plantar (HHP) é uma doença de alto impacto psicossocial, e a simpatectomia lombar endoscópica (SLE) tem se mostrado a melhor escolha de tratamento. Porém, há algumas preocupações como suor compensatório (SC) e efeitos sexuais (ES), particularmente em homens. Objetivos O objetivo deste estudo foi avaliar a eficácia a longo prazo da SLE para controlar a HHP em homens, seus efeitos colaterais e as modificações sexuais percebidas. Métodos Tratou-se de um estudo transversal incluindo apenas pacientes do sexo masculino operados de HHP por meio de SLE entre 2014 e 2022 em consultório particular. Por meio de entrevistas remotas, os pacientes foram questionados sobre os sintomas antes e depois da SLE e sobre a evolução pós-operatória da HHP, assim como foram questionados objetivamente sobre qualquer ES percebido durante o pós-operatório. Também foram aplicados questionários validados de qualidade de vida para hiperidrose e função erétil. Resultados Foram entrevistados 10 pacientes do sexo masculino com média de 4,26±2,86 anos pós-SLE. Oito deles (80%) obtiveram resposta completa (≥80% de redução do suor) no primeiro mês após a cirurgia e mantiveram a resposta na entrevista. Dois pacientes tiveram resposta parcial. Em seis pacientes, ocorreu SC, com cinco relatando-a como não problemática. Seis pacientes relataram algum tipo de ES, mas nenhum apresentou disfunção erétil. Todos os pacientes avaliaram o resultado funcional da SLE como bom (10%), muito bom (30%) ou excelente (60%). Conclusões A SLE pode tratar de forma eficaz a HHP nesses pacientes, melhorando a qualidade de vida e proporcionando efeitos duradouros no controle da HHP, com algumas disfunções sexuais transitórias que não prejudicam a vida sexual. (HHP psicossocial (SLE tratamento Porém SC (SC , (ES) homens percebidas Tratouse Tratou 201 202 particular remotas pósoperatória pós operatória pósoperatório. pósoperatório operatório. operatório pós-operatório erétil 1 426286 4 26 2 86 4,26±2,8 pósSLE. pósSLE SLE. pós-SLE 80% 80 (80% ≥80% (≥80 entrevista parcial relatandoa relatando problemática 10%, 10% (10%) 30% 30 (30% 60%. 60 60% . (60%) sexual (ES 20 42628 8 4,26±2, (80 ≥80 (≥8 (10% 3 (30 6 (60% 4262 4,26±2 (8 ≥8 (≥ (10 (3 (60 426 4,26± ( ≥ (1 (6 42 4,26 4,2 4,
Abstract Background Plantar hyperhidrosis (PHH) is a disease with high psychosocial impact, and endoscopic lumbar sympathectomy (ELS) has been shown to be the best choice for treatment, but with some concerns such as compensatory sweating (CS) and sexual effects (SE), particularly in men. Objectives The aim of this study is to evaluate the long-term effectiveness of ELS for controlling PHH in men, its side effects, and perceived sexual modifications. Methods A cross-sectional study including only male patients operated for PHH with ELS between 2014–2022 at a private practice. During remote interviews, patients were asked about symptoms before and after ELS and about the postoperative effects on PHH. They were also objectively asked about any SE during the postoperative period. Validated quality of life for hyperhidrosis and erectile function questionnaires were also administered. Results 10 male patients averaging 4.26±2.86 years post-ELS were interviewed. Eight of them (80%) achieved complete response (≥80% of sweat reduction) in the first month after surgery and this response was maintained up to the interview date. Two patients had partial response. In six patients, CS occurred, with 5 reporting it as non-troublesome. Six patients reported some type of SE, but none reported erectile dysfunction. Regarding the functional results, all patients rated ELS from good (10%) to very good (30%) or excellent (60%). Conclusions Endoscopic lumbar sympathectomy was effective for treatment of plantar hyperhidrosis in these patients, improving their quality of life and providing lasting PHH control, with some transient sexual dysfunctions that did not impair their sexual life. (PHH impact (ELS (CS , (SE) men longterm long term modifications crosssectional cross sectional 20142022 2014 2022 2014–202 practice interviews period administered 1 426286 4 26 2 86 4.26±2.8 postELS post interviewed 80% 80 (80% ≥80% (≥80 reduction date occurred nontroublesome. nontroublesome non troublesome. troublesome non-troublesome dysfunction results 10% (10% 30% 30 (30% 60%. 60 60% . (60%) control (SE 2014202 201 202 2014–20 42628 8 4.26±2. (80 ≥80 (≥8 (10 3 (30 6 (60% 201420 20 2014–2 4262 4.26±2 (8 ≥8 (≥ (1 (3 (60 20142 2014– 426 4.26± ( ≥ (6 42 4.26 4.2 4.
5.
The SISBIOTA-Diptera Brazilian Network: A long-term survey of Diptera from unexplored Brazilian Western Arc of Amazon, Cerrado, and Pantanal SISBIOTADiptera SISBIOTA Network longterm long term Amazon Cerrado
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Lamas, Carlos José Einicker
; Fachin, Diego Aguilar
; Falaschi, Rafaela Lopes
; Alcantara, Daniel Máximo Correa de
; Ale-Rocha, Rosaly
; Amorim, Dalton de Souza
; Araújo, Maíra Xavier
; Ascendino, Sharlene
; Baldassio, Letícia
; Bellodi, Carolina Ferraz
; Bravo, Freddy
; Calhau, Julia
; Capellari, Renato Soares
; Carmo-Neto, Antonio Marcelino do
; Cegolin, Bianca Melo
; Couri, Márcia Souto
; Carvalho, Claudio José Barros de
; Dios, Rodrigo de Vilhena Perez
; Falcon, Aida Vanessa Gomez
; Fusari, Livia Maria
; Garcia, Carolina de Almeida
; Gil-Azevedo, Leonardo Henrique
; Gomes, Marina Morim
; Graciolli, Gustavo
; Gudin, Filipe Macedo
; Henriques, Augusto Loureiro
; Krolow, Tiago Kütter
; Mendes, Luanna Layla
; Limeira-de-Oliveira, Francisco
; Maia, Valéria Cid
; Marinoni, Luciane
; Mello, Ramon Luciano
; Mello-Patiu, Cátia Antunes de
; Morales, Mírian Nunes
; Oliveira, Sarah Siqueira
; Patiu, Claudemir
; Proença, Barbara
; Pujol-Luz, Cristiane Vieira de Assis
; Pujol-Luz, José Roberto
; Rafael, José Albertino
; Riccardi, Paula Raile
; Rodrigues, João Paulo Vinicios
; Roque, Fabio de Oliveira
; Sallum, Maria Anice Mureb
; Santis, Marcelo Domingos de
; Santos, Charles Morphy Dias dos
; Santos, Josenilson Rodrigues dos
; Savaris, Marcoandre
; Shimabukuro, Paloma Helena Fernandes
; Silva, Vera Cristina
; Schelesky-Prado, Daniel de Castro
; Silva-Neto, Alberto Moreira da
; Camargo, Alexssandro
; Sousa, Viviane Rodrigues de
; Urso-Guimarães, Maria Virginia
; Wiedenbrug, Sofia
; Yamaguchi, Carolina
; Nihei, Silvio Shigueo
.
ABSTRACT The SISBIOTA-BRASIL was a three-year multimillion-dollar research program of the Brazilian government to document plants and animals in endangered/understudied areas and biomes in Brazil. Distributional patterns and the historical events that generated them are extensively unknown regarding Brazilian fauna and flora. This deficiency hinders the development of conservation policies and the understanding of evolutionary processes. Conservation decisions depend on precise knowledge of the taxonomy and geographic distribution of species. Given such a premise, we proposed to research the diversity of Diptera of the Brazilian western arc of Amazon, Cerrado, and Pantanal in the states of Mato Grosso, Mato Grosso do Sul, and Rondônia. Three important biomes of the South American continent characterize these Brazilian states: Amazon forest, Cerrado (Brazilian Savannah), and Pantanal. Besides their ecological relevance, these biomes historically lack intensive entomological surveys. Therefore, they are much underrepresented in the Brazilian natural history collections and in the scientific literature, which is further aggravated by the fact that these areas are being exponentially and rapidly converted to commercial lands. Our project involved over 90 collaborators from 24 different Brazilian institutions and one from Colombia among researchers, postdocs, graduate and undergraduate students, and technicians. We processed and analyzed nearly 300,000 specimens from ~60 families of Diptera collected with a large variety of methods in the sampled areas. Here, we provide a detailed overview of the genera and species diversity of 41 families treated. Our results point to a total of 2,130 species and 514 genera compiled and identified for the three states altogether, with an increase of 41% and 29% in the numbers of species and genera known for the three states combined, respectively. Overall, the 10 most species-rich families were Tachinidae, Cecidomyiidae, Tabanidae, Psychodidae, Sarcophagidae, Stratiomyidae, Bombyliidae, Syrphidae, Tephritidae, and Asilidae. The 10 most diverse in the number of genera were Tachinidae, Stratiomyidae, Asilidae, Mycetophilidae, Syrphidae, Tabanidae, Muscidae, Dolichopodidae, Sarcophagidae, and Chloropidae. So far, 111 scientific papers were published regarding taxonomic, phylogenetic, and biogeographical aspects of the studied families, with the description of 101 new species and three new genera. We expect that additional publications will result from this investigation because several specimens are now curated and being researched by specialists. SISBIOTABRASIL SISBIOTA BRASIL threeyear year multimilliondollar multimillion dollar endangeredunderstudied endangered understudied Brazil flora processes premise Sul Rondônia forest Savannah, Savannah , Savannah) relevance surveys Therefore literature lands 9 2 researchers postdocs students technicians 300000 300 000 300,00 60 ~6 Here 4 treated 2130 130 2,13 51 altogether 29 combined respectively Overall 1 speciesrich rich Tachinidae Cecidomyiidae Tabanidae Psychodidae Sarcophagidae Stratiomyidae Bombyliidae Syrphidae Tephritidae Asilidae Mycetophilidae Muscidae Dolichopodidae Chloropidae far 11 taxonomic phylogenetic specialists 30000 30 00 300,0 6 ~ 213 13 2,1 5 3000 3 0 300, 21 2,
6.
Endoscopic lumbar sympathectomy as a treatment option for primary erythromelalgia - case report and review
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Loureiro, Marcelo de Paula
; Novais, Pietro Maran
; Paulin, João Augusto Nocera
; Almeida, Daniel Benzecry de
; Lemos Junior, Arlindo Nascimento de
.
Resumo Eritromelalgia é uma doença rara caracterizada por dor, edema, eritema e hipertermia nos membros. É extremamente refratária a medicamentos e não tem um tratamento definido, causando comorbidades psicológicas para o paciente. Descrevemos o caso de um menino de 17 anos que possuía eritromelalgia há quase 4 anos antes de ser submetido a um tratamento efetivo. Foi realizada simpatectomia lombar endoscópica bilateral limitada à ressecção dos gânglios L2 e L3. Após 4 semanas do procedimento, o paciente teve diminuição significativa dos seus sintomas e, com 8 meses de seguimento, permanece praticamente assintomático. A simpatectomia lombar endoscópica foi um tratamento eficaz para eritromelalgia primária em um adolescente, com redução excepcional dos seus sintomas. dor edema membros definido 1 efetivo L L3 procedimento seguimento assintomático adolescente
Abstract Erythromelalgia is a rare disease, involving pain, edema, redness, and hyperthermia in the limbs. It is extremely refractory to drugs, has no defined treatment, and causes psychological comorbidities in the patient. We describe a case of erythromelalgia involving a 17-year-old boy who had been suffering from the disease for almost 4 years prior to finding an effective treatment. A bilateral endoscopic lumbar sympathectomy was performed, limited to L2 and L3 resections. Four weeks after the procedure, the patient’s symptoms were significantly mitigated and at 8 months follow-up he remained almost asymptomatic. Endoscopic lumbar sympathectomy was an effective treatment for primary erythromelalgia in this teenager, with exceptional reduction of his symptoms. pain edema redness limbs drugs patient 17yearold yearold 17 year old performed L resections procedure patients s followup follow up asymptomatic teenager 1
7.
Avalição da eficácia de dispositivo protetor de lipoaspiração modificado: estudo experimental em suínos modificado
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ARAÚJO, LUIZ ROBERTO REIS
; LOUREIRO, MARCELO DE PAULA
; HIRT, BRUNO
; CRUZ, GABRIELA SGRANCE
; SANTOS, LUIGIA MARIA NARDI
; SANTOS, MATEUS HERCULANO BONIFÁCIO
.
RESUMO A lipoaspiração é um dos procedimentos mais comuns na especialidade de cirurgia plástica. No levantamento da ISAPS de 2018 foi a segunda cirurgia mais realizada em todo o mundo. Devido aos movimentos repetitivos próprios da cirurgia, fricção importante é gerada no local e as consequências são queimaduras cutâneas que podem deixar cicatrizes inestéticas e discromias. O objetivo deste estudo é criar um protótipo de um dispositivo protetor da pele, a partir de um modelo antigo, que sirva a esse propósito, e observar sua funcionalidade e os efeitos da sua utilização na pele de suínos. Os testes foram realizados em animais mortos sem sofrimento disponibilizados pelo setor de Medicina Veterinária da Universidade Positivo. Foram feitas três incisões no abdome do animal para passagem da cânula de lipoaspiração e outras três para a inserção e utilização do protótipo, bem como para comparação com o dispositivo modelo. O tempo estabelecido de movimentos de lipoaspiração foi de vinte minutos, realizados com a cânula de 5mm diretamente em contato com a pele e dentro do protótipo. Foi avaliada a ergonomia do protótipo, facilidade de inserção e travamento adequado na pele com diferentes trações. Observação e avaliação da pele após os procedimentos e medição (cm) das incisões foram realizadas. O protótipo do dispositivo protetor cutâneo de lipoaspiração criado apresentou fácil manuseio e mecanismo de travamento na pele mais eficiente quando comparado ao modelo utilizado. A incisão cutânea para uso do protótipo foi ligeiramente maior e a pele não apresentou sinais de queimadura. plástica 201 mundo discromias antigo propósito suínos Positivo minutos mm trações cm (cm realizadas utilizado queimadura 20 2
ABSTRACT Liposuction is one of the most common procedures in the plastic surgery specialty. In the 2018 ISAPS survey, it was the second most performed surgery worldwide. Due to the repetitive movements typical of the surgery, significant friction is generated at the site, and the consequences are skin burns that can leave unsightly scars and dyschromias. This study aims to create a skin protective device prototype from an old model, which serves this purpose, and to observe its functionality and its effects on the pigskin. The tests were carried out on dead animals without suffering provided by the Veterinary Medicine sector at Universidade Positivo. Three incisions were made in the animal’s abdomen to pass the liposuction cannula and another three for the insertion and use of the prototype to compare it with the model device. The established time for liposuction movements was twenty minutes, performed with the 5mm cannula directly in contact with the skin and inside the prototype. The prototype’s ergonomics, ease of insertion, and good locking on the skin with different tractions were evaluated. Observation and evaluation of the skin were performed after procedures and incisions’ measurements (cm). The cutaneous liposuction protective device prototype presented easy handling and a more efficient skin locking mechanism than the model used. The skin incision for using the prototype was slightly larger, and the skin showed no burning signs. specialty 201 survey worldwide site dyschromias purpose pigskin Positivo animal s minutes mm prototypes ergonomics evaluated cm. cm . (cm) used larger signs 20 (cm 2
8.
GASTROGASTRIC FISTULA AFTER ROUX-EN-Y GASTRIC BYPASS: A CASE REPORT AND REVIEW OF LITERATURE
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ALYAQOUT, Khaled
; ALMAZEEDI, Sulaiman
; ALHADDAD, Mohanned
; EFTHIMIOU, Evangelos
; LOUREIRO, Marcelo de Paula
.
ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)
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https://doi.org/10.1590/0102-672020190001e1509
1356 downloads
9.
Modelos animais na síndrome metabólica.
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Fuchs, Taíse
; Loureiro, Marcelo de Paula
; Macedo, Lano Emerson
; Nocca, David
; Nedelcu, Marius
; Costa-Casagrande, Thaís Andrade
.
RESUMO O conhecimento sobre modelos animais para estudo metabólico representa a base da pesquisa nessa área. Este trabalho tem por objetivo revisar os principais modelos animais a serem utilizados no estudo da obesidade e da síndrome metabólica. Para isso, pesquisa no banco de dados Pubmed foi realizada usando as palavras-chave “animal models”, “obesity”, "metabolic syndrome”, e “bariatric surgery”. Várias espécies de animais podem ser usadas para o estudo de distúrbios metabólicos, no entanto, os roedores, tanto modelos monogênicos quanto modelos de obesidade induzida por dieta (DIO), são os animais mais utilizados nessa área. Animais monogênicos são a melhor escolha se apenas um aspecto estiver sendo avaliado. Animais DIO tendem a demonstrar melhor a interação entre doença, ambiente e gene. No entanto, eles ainda não são totalmente eficazes para a compreensão de todos os mecanismos dessa doença.
ABSTRACT Knowledge about animal models for metabolic study is the basis of research in this area. This work aims to review the main animal models used in the study of obesity and metabolic syndrome. For this, we performed a search in the Pubmed database using the terms “animal models”, “obesity”, “metabolic syndrome” and “bariatric surgery”. Several species of animals can be used for the study of metabolic disorders. However, rodents are the most commonly used, both as monogenic models and as diet-induced obesity (DIO) ones. Monogenic animals are the best choice if only one aspect is being evaluated. DIO animals tend to better demonstrate the interaction between disease, environment and genetics. However, they are still not fully effective in providing understanding of all disease mechanisms.
https://doi.org/10.1590/0100-6991e-20181975
5844 downloads
10.
LAPAROSCOPIC RESECTION OF GASTROINTESTINAL STROMAL TUMORS (GIST)
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Loureiro, Marcelo de Paula
; ALMEIDA, Rômulo Augusto Andrade de
; Claus, Christiano Marlo Paggi
; Bonin, Eduardo Aimoré
; Cury-Filho, Antônio Moris
; Dimbarre, Daniellson
; COSTA, Marco Aurélio Raeder da
; VITAL, Marcílio Lisboa
.
ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)
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Racional: Os tumores estromais ou mesenquimais gastrointetinais (GIST) são lesões originárias da parede do tubo digestivo cujo tratamento requer remoção cirúrgica. Diversas técnicas por via laparoscópica - gastrectomias e ressecções segmentares - têm sido empregadas com sucesso. Objetivo: Apresentar a experiência de um serviço de cirurgia com ressecção laparoscópica de GIST. Métodos: Foram avaliados 15 pacientes com GIST operados revisados retrospectivamente. Treze tiveram lesões gástricas, das quais 10 eram subepiteliais entre 2-8 cm. Três eram lesões exofíticas puras. Dois apresentavam lesões no intestino delgado. O tratamento cirúrgico por laparoscopia consistiu de duas gastrectomias distais; 11 ressecções gástricas em cunha e duas enterectomias segmentares. Sutura mecânica foi utilizada na maioria dos doentes, exceto em seis com suturas absorvíveis manuais. Não houve conversões para laparotomia. Resultados: O tempo médio das operações foi de 89±92 min (40-420). A hospitalização média foi de três dias (2-6). Não houve fístula, sangramento pós-operatório ou necessidade de reintervenção por complicação cirúrgica. O seguimento médio pós-operatorio foi de 38±17 meses (6-60). Três pacientes foram encaminhados para terapia adjuvante com mesilato de imatinib, um deles por recidiva precoce aos cinco meses, e os outros dois por apresentarem risco moderado para recidiva. Conclusão: A ressecção laparoscópica de GIST, mesmo os maiores de 5 cm, é procedimento factível e seguro.
Background : Gastrointestinal mesenchymal or stromal tumors (GIST) are lesions originated on digestive tract walls, which are treated by surgical resection. Several laparoscopic techniques, from gastrectomies to segmental resections, have been used successfully. Aim : Describe a single center experience on laparoscopic GIST resection. Method : Charts of 15 operated patients were retrospectively reviewed. Thirteen had gastric lesions, of which ten were sub epithelial, ranging from 2-8 cm; and three were pure exofitic growing lesions. The remaining two patients had small bowel lesions. Surgical laparoscopic treatment consisted of two distal gastrectomies, 11 wedge gastric resections and two segmental enterectomies. Mechanical suture was used in the majority of patients except on six, which underwent resection and closure using manual absorbable sutures. There were no conversions to open technique. Results : Mean operative time was 1h 29 min±92 (40-420 min). Average lenght of hospital stay was three days (2-6 days). There were no leaks, postoperative bleeding or need for reintervention. Mean postoperative follow-up was 38±17 months (6-60 months). Three patients underwent adjuvant Imatinib treatment, one for recurrence five months postoperatively and two for tumors with moderate risk for recurrence . Conclusion : Laparoscopic GIST resection, not only for small lesions but also for tumors above 5 cm, is safe and acceptable technique.
https://doi.org/10.1590/0102-6720201600010001
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11.
Effectiveness of a reusable low-cost balloon trocar dissection device in the creation of preperitoneal space during endoscopic surgery. An experimental study in swine
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Nácul, Miguel Prestes
; Cavazzola, Leandro Totti
; Loureiro, Marcelo de Paula
; Bonin, Eduardo Aimoré
; Ferreira, Paulo Roberto Walter
.
PURPOSE: To evaluate a new, low-cost, reusable balloon trocar device for dissection of the preperitoneal space during endoscopic surgery.METHODS:Twenty swine (weight: 15-37 kg) were randomized to two groups, according to whether the preperitoneal space was created with a new balloon device manufactured by Bhio-Supply (group B) or with the commercially available OMSPDB 1000(r) balloon device manufactured by Covidien (group C). Quality and size of the created preperitoneal space, identification of anatomic structures, balloon dissection time, total procedure time, balloon resistance and internal pressure after insufflation with 300 mL of ambient air, balloon-related complications, and procedure cost were assessed.RESULTS:No significant differences in dissection time, total procedure time, or size of the created preperitoneal space were found between the groups. Balloons in group B had a significantly higher internal pressure compared to balloons in group C. None of the balloons ruptured during the experiment. Three animals in group C had balloon-related peritoneal lacerations. Despite a higher individual device cost, group B had a lower procedure cost over the entire experiment.CONCLUSION:The new balloon device is not inferior to the commercially available device in terms of the safety and effectiveness for creating a preperitoneal space in swine.
https://doi.org/10.1590/S0102-865020150090000010
2466 downloads
12.
Long-term professional performance of minimally invasive surgery post-graduates
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Loureiro, Marcelo de Paula
; Claus, Christiano Maggi
; Bonin, Eduardo Aimoré
; Cury Filho, Antonio
; Dimbarre, Danielson
; Trauczinski, Pedro
; Swanstrom, Lee
.
Revista do Colégio Brasileiro de Cirurgiões
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OBJETIVO: avaliar a contribuição de um programa de pós-graduação na carreira profissional de seus egressos. MÉTODOS: os participantes foram convidados a responder questionário com perguntas relacionadas a eventuais mudanças em seu desempenho profissional após o término do curso. RESULTADOS: quarenta e três (76,7%) dos 56 participantes elegíveis para o estudo responderam aos questionários. A maioria dos participantes, 32 (74,4%) já tinha contato prévio com a cirurgia laparoscópica, porém, apenas 14 (32,5%) relataram a experiência como cirurgião principal. As expectativas sobre o curso foram alcançadas ou superadas para 36 (83,7%) participantes. Trinta e sete (86%) incorporaram procedimentos minimamente invasivos em sua prática cirúrgica diária. E também 37 (86%) relataram melhorias em seus rendimentos superiores a 10%, e ainda 12% relataram aumento superior a 100% em seus rendimentos, diretamente relacionado com o incremento da atividade laparoscópica. CONCLUSÃO: o programa em cirurgia minimamente invasiva proporciona um elevado grau de satisfação aos seus participantes, e os capacita a realizar procedimentos técnicos mais complexos, como as suturas, além de melhorar seu desempenho economico profissional.
OBJECTIVE: to evaluate the contribution of a post-graduation program in surgeons professional careers. METHODS: participants were asked to answer a questionnaire with questions related to possible changes in their professional performance after the end of the course. RESULTS: forty-three (76.7%) of the 56 participants eligible for the study responded to the questionnaires. Most participants, 32 (74.4%), had previous contact with laparoscopic surgery; however, only 14 (32.5%) reported the experience as primary surgeon. The expectations on the course were reached or exceeded for 36 (83.7%) participants. Thirty-seven (86%) incorporated minimally invasive procedures in their daily surgical practice, 37 (86%) reported improvements in their income above 10% and 12% reported income increase of over 100%, directly related to their increase of laparoscopic activity. CONCLUSION: the program in minimally invasive surgery provides a high level of satisfaction to its participants, enables them to perform more complex technical procedures, such as sutures, and improves their professional economic performance.
https://doi.org/10.1590/0100-69912015002011
1628 downloads
13.
Development of laparoscopic skills in Medical students naive to surgical training
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Cavalini, Worens Luiz Pereira
; Claus, Christiano Marlo Paggi
; Dimbarre, Daniellson
; Cury Filho, Antonio Moris
; Bonin, Eduardo Aimoré
; Loureiro, Marcelo de Paula
; Salvalaggio, Paolo
.
Objetivo Avaliar o aprendizado de habilidades laparoscópicas básicas em estudantes de Medicina submetidos a treinamento em um simulador.Métodos Estudantes de Medicina do primeiro e segundo ano participaram de um treinamento de exercícios de laparoscopia em simuladores. Nenhum estudante havia cursado a disciplina de técnica operatória ou teve exposição prévia a cirurgias ou treinamento cirúrgico. Os mesmos tiveram seu tempo coletado antes e após treinamento de 150 minutos. A aquisição de habilidade foi medida comparando tempo e pontuações dos alunos em relação a cirurgiões instrutores em cirurgia laparoscópica.Resultados O trabalho teve a participação de 68 alunos, com média de idade de 20,4 anos. Houve predomínio de alunos do primeiro ano (62%). Na comparação pré e pós-treino, todos os alunos obtiveram melhora de desempenho em pontuação e tempo dos exercícios, com significância estatística (p<0,001). A pontuação apresentou variação de melhora de 294.1 a 823%. Análise univariada e multivariada identificaram que alunos do segundo ano obtiveram um maior ganho de desempenho com o treinamento.Conclusões Estudantes de Medicina nunca expostos à técnicas cirúrgicas adquirem habilidades laparoscópicas básicas em treinamento sistematizado em simuladores. Alunos do segundo ano apresentaram melhor desempenho em relação a alunos do primeiro ano.
Objective To assess the acquisition of basic laparoscopic skills of Medical students trained on a surgical simulator.Methods First- and second-year Medical students participated on a laparoscopic training program on simulators. None of the students had previous classes of surgical technique, exposure to surgical practice nor training prior to the enrollment in to the study. Students´ time were collected before and after the 150-minute training. Skill acquisition was measured comparing time and scores of students and senior instructors of laparoscopic surgeryResults Sixty-eight students participated of the study, with a mean age of 20.4 years, with a predominance of first-year students (62%). All students improved performance in score and time, after training (p<0,001). Score improvement in the exercises ranged from 294.1 to 823%. Univariate and multivariate analyses identified that second-year Medical students have achieved higher performance after training.Conclusions Medical students who had never been exposed to surgical techniques can acquire basic laparoscopic skills after training in simulators. Second-year undergraduates had better performance than first-year students.
https://doi.org/10.1590/S1679-45082014AO3237
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14.
Minilaparoscopic fundoplication: technical adaptations and initial experience
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Dimbarre, Daniellson
; Loureiro, Paula Marcelo de
; Claus, Christiano
; Carvalho, Gustavo
; Trauczynski, Pedro
; Elias, Fabiano
.
CONTEXTO: A doença do refluxo gastroesofágico (DRGE) é uma doença altamente prevalente. O seu tratamento é dividido em modificações de estilo de vida, tratamento médico e cirúrgico. A cirurgia laparoscópica é o tratamento padrãoouro. Nas últimas décadas houve uma extensa pesquisa sobre procedimentos menos agressivos do que a laparoscopia e com melhores resultados estéticos. A minilaparoscopia vem "reemergindo" como método seguro, eficaz e com excelentes resultados estéticos em pacientes selecionados, tratados para DRGE. É apresentada uma série de 27 pacientes tratados para a DRGE por minilaparoscopia. MÉTODOS: Entre outubro de 2009 e julho de 2011, o total de 27 pacientes foi submetido a fundoplicatura por videominilaparoscopia. Foram utilizados um trocarte de 10 mm, um telescópio de 30 graus e quatro trocarteres de 3 mm nas posições regulares. Os passos cirúrgicos são feitos sem modificações, de maneira habitual. Fita cardíaca, agulhas de sutura e, eventualmente, saco extrator e gaze são colocados e retirados através do portal umbilical. Com esses ajustes técnicos, podese realizar o procedimento de forma segura e eficaz, semelhantemente à técnica laparoscópica padrão. CONCLUSÃO: Hiatoplastia associada à fundoplicatura laparoscópica, utilizandose de instrumentos minilaparoscópicos é método seguro, viável e eficaz. Se comparado a outros "novos acessos", tem resultado estético espetacular. Pode ser realizado com apenas pequenos ajustes técnicos, por qualquer cirurgião experiente em laparoscopia e é perfeitamente adaptável a nossa realidade financeira.
CONTEXT: Gastroesophageal reflux diasease (GERD) is a highly prevalent disease. Treatment is divided into lifestyle modifications, medical and surgical treatment. Surgical laparoscopy is the gold standard treatment. In the last decade, there were an extensive research on procedures, less aggressive than laparoscopy and with better esthetic results. Minilaparoscopy is "reemerging" as a safe, effective and with excellent cosmetic results in selected patients treated for gastroesophageal reflux diasease. We present a serie of 27 patients treated for GERD by minilaparoscopic laparoscopy. MATERIAL: Between October 2009July 2011 a total of 27 patients underwent fundoplication by minilaparoscopy. It is used one 10mm trocar, a telescope of 30 degrees and four 3 mm trocars at regular positions. Regular surgical steps are done with no modifications. Cardiac tape, suture needles, and eventually extracting bag, gauze, are placed and taked out through the umbilical port. With these technical adjustments, we can perform the procedure safely and effectively, similarly to standard laparoscopic technique. RESULTS: Of the 27 patients, 22 were female and 5 male. The average body mass index was 25.5 kg/m². Hiatal hernias were small (<3 cm) in 24 patients. Mean operative time was 60 minutes. In all cases the hiatoplasty was performed with simple or 'x' stiches of 2.0 Ethibond. There was no need for conversion to standard laparoscopy or open surgery. The length of hospital stay was less than or equal to 24 hours in all patients. In this series of patients there were no postoperative complications. We did not observe any complication of the surgical wound. There were no evidence of recurrence of symptoms or endoscopic changes. CONCLUSION: Hiatoplasty associated with fundoplication using minilaparoscopic instruments is safe, feasible and effective. If compared to other "new access", has a spectacular esthetic results. Can be done with only minor technical adjustments, for any experienced laparoscopic surgeon, and is perfectly adaptable to our financial reality.
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15.
Apendicite aguda pós colonoscopia: desafio diagnóstico e tratamento minimamente invasivo - relato de caso
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Loureiro, Marcelo de Paula
; Bonin, Eduardo
; Leiner, Camila
; Weigmann, Sheila Cristina
; Fontana, Aline
.
Revista do Colégio Brasileiro de Cirurgiões
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We present a case of a 54-year-old man with abdominal pain four hours after colonoscopy and upper endoscopy. Since he had had a polipectomy and an ulcer was seen in the terminal ileum, the diagnosis of appendicitis was even more difficult. The authors discuss the rarity of this situation and the minimally invasive approach to treat appendicitis.
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