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Resumo O objetivo deste artigo é avaliar associação entre peso ao nascer e asma na vida adulta pela análise de equações estruturais. Estudo de coorte com 1.958 participantes de 23-25 anos, residentes em Ribeirão Preto, São Paulo, Brasil. Foram aplicados questionários padronizados e avaliado a função pulmonar, incluindo hiper-reatividade brônquica com metacolina. O modelo teórico foi proposto para explorar os efeitos do peso ao nascer e asma na vida adulta. Asma, status socioeconômico ao nascimento (SES Nascimento) e status socioeconômico adulto (SES adulto) foram obtidos por um construto. Variáveis estudadas: idade materna, idade, sexo, cor da pele, índice de massa corporal (IMC), tabagismo, história de asma dos pais, história de infecção respiratória antes dos cinco anos, história de internação por doença pulmonar antes dos dois anos e atopia. 14,1% dos participantes foram diagnosticados com asma. Peso ao nascer foi associado com asma (Coeficiente Padronizado - CPtotal=-0,110; p=0,030), e foi observado efeito indireto (CPindireto=-0,220; p=0,037), mediado por internação antes dos dois anos e infecção respiratória antes dos 5 anos. Menor peso ao nascer aumentou o risco para asma na vida adulta e as variáveis SES Nascimento e SES adulto foram subjacentes a esta associação. estruturais 1958 1 958 1.95 2325 23 25 23-2 Preto Paulo Brasil hiperreatividade hiper reatividade metacolina Asma construto estudadas materna sexo pele IMC, IMC , (IMC) tabagismo pais atopia 141 14 14,1 Coeficiente CPtotal=0,110 CPtotal0110 CPtotal CPtotal= 0,110 0 110 CPtotal=-0,110 p=0,030, p0030 p p=0,030 030 p=0,030) CPindireto=0,220 CPindireto0220 CPindireto CPindireto= 0,220 220 (CPindireto=-0,220 p=0,037, p0037 p=0,037 037 p=0,037) 195 95 1.9 232 2 23- (IMC 14, CPtotal=0,11 CPtotal011 0110 0,11 11 CPtotal=-0,11 p003 p=0,03 03 CPindireto=0,22 CPindireto022 0220 0,22 22 (CPindireto=-0,22 19 9 1. CPtotal=0,1 CPtotal01 011 0,1 CPtotal=-0,1 p00 p=0,0 CPindireto=0,2 CPindireto02 022 0,2 (CPindireto=-0,2 CPtotal=0, CPtotal0 01 0, CPtotal=-0, p0 p=0, CPindireto=0, CPindireto0 02 (CPindireto=-0, CPtotal=0 CPtotal=-0 p=0 CPindireto=0 (CPindireto=-0 CPtotal=- p= (CPindireto=- (CPindireto= (CPindireto

Abstract This article aims to evaluate the association between birth weight and asthma in adulthood, estimated by employing structural equation modeling. Cohort study with 1,958 participants aged 23-25 years from Ribeirão Preto, São Paulo, Brazil. Standardized questionnaires were applied and pulmonary function evaluated, including bronchial reactivity with methacholine. A theoretical model was proposed to explore the effects of birth weight and asthma in adulthood. Asthma, socioeconomic status at birth (Birth SES), and current socioeconomic status (Adult SES) were obtained by constructs. Maternal age, sex, skin color, body mass index (BMI), smoking, parental asthma history, history of respiratory infection before five years old, history of hospitalization for lung disease before two years old, and atopy were the studied variables. 14.1% of participants were diagnosed with asthma. Birth weight was associated with asthma (Standardized Coefficient - SCtotal=-0.110; p=0.030), and an indirect effect was also observed (SCindirect=-0.220; p=0.037), mediated by hospitalization before two years and respiratory infection before five years. Lower birth weight showed an increased risk of asthma in adulthood and the SES Birth and Adult SES variables underlie this association. modeling 1958 1 958 1,95 2325 23 25 23-2 Preto Paulo Brazil evaluated methacholine Asthma SES, , constructs age sex color BMI, BMI (BMI) smoking old 141 14 14.1 SCtotal=0.110 SCtotal0110 SCtotal SCtotal= 0.110 0 110 SCtotal=-0.110 p=0.030, p0030 p p=0.030 030 p=0.030) SCindirect=0.220 SCindirect0220 SCindirect SCindirect= 0.220 220 (SCindirect=-0.220 p=0.037, p0037 p=0.037 037 p=0.037) 195 95 1,9 232 2 23- (BMI 14. SCtotal=0.11 SCtotal011 0110 0.11 11 SCtotal=-0.11 p003 p=0.03 03 SCindirect=0.22 SCindirect022 0220 0.22 22 (SCindirect=-0.22 19 9 1, SCtotal=0.1 SCtotal01 011 0.1 SCtotal=-0.1 p00 p=0.0 SCindirect=0.2 SCindirect02 022 0.2 (SCindirect=-0.2 SCtotal=0. SCtotal0 01 0. SCtotal=-0. p0 p=0. SCindirect=0. SCindirect0 02 (SCindirect=-0. SCtotal=0 SCtotal=-0 p=0 SCindirect=0 (SCindirect=-0 SCtotal=- p= (SCindirect=- (SCindirect= (SCindirect

https://doi.org/10.1590/1413-81232024295.02362023

Position statement of the Brazilian Palliative Care Academy on withdrawing and withholding life-sustaining interventions in the context of palliative care lifesustaining life sustaining
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Vidal, Edison Iglesias de Oliveira

; Ribeiro, Sabrina Correa da Costa

; Kovacs, Maria Júlia

; Máximo da Silva, Luciano

; Sacardo, Daniele Pompei

; Iglesias, Simone Brasil de Oliveira

; Silva, Josimário João da

; Neves, Cinara Carneiro

; Ribeiro, Diego Lima

; Lopes, Fernanda Gomes

Critical Care Science

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2024, Volume 36 elocation e20240021en

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O tema da suspensão e da não implementação de intervenções de suporte de vida constitui importante fonte de controvérsia entre profissionais de saúde que lidam com pacientes com doenças graves. Decisões equivocadas, tanto em termos de introdução/manutenção, como de suspensão/não introdução dessas medidas representam fonte de sofrimento evitável para pacientes, seus entes queridos e profissionais de saúde. O presente documento representa o posicionamento do Comitê de Bioética da Academia Nacional de Cuidados Paliativos sobre essa questão e estabelece sete princípios para guiar, do ponto de vista da bioética, a abordagem de situações relacionadas a tal tema no contexto dos cuidados paliativos no Brasil. O posicionamento estabelece a equivalência entre a retirada e a não implementação de intervenções de suporte de vida e a inadequação relacionada a iniciar ou manter tais medidas em contextos em que elas estejam em desacordo com os valores e os objetivos de cuidado definidos em conjunto com pacientes e seus familiares. Adicionalmente, o posicionamento distingue tratamentos fúteis em senso estrito de tratamentos potencialmente inapropriados e elucida sua implicação crucial para a adequação do processo de tomada de decisão médica nesse contexto. Finalmente, o texto aborda a questão da objeção de consciência e seus limites; determina que o compromisso ético pelo alívio do sofrimento não deve ser influenciado pela decisão por empregar ou não intervenções de suporte de vida e adverte contra o uso de linguagem que induza pacientes/familiares a acreditarem que apenas uma das opções disponíveis relacionadas à utilização ou não dessas medidas possibilitará o alívio do sofrimento. graves equivocadas introduçãomanutenção manutenção introdução/manutenção suspensãonão guiar bioética Brasil familiares Adicionalmente Finalmente limites pacientesfamiliares

ABSTRACT The issue of withrawing and withholding life-sustaining interventions is an important source of controversy among healthcare professionals caring for patients with serious illnesses. Misguided decisions, both in terms of the introduction/maintenance and the withdrawal/withholding of these measures, represent a source of avoidable suffering for patients, their loved ones, and healthcare professionals. This document represents the position statement of the Bioethics Committee of the Brazilian Palliative Care Academy on this issue and establishes seven principles to guide, from a bioethical perspective, the approach to situations related to this topic in the context of palliative care in Brazil. The position statement establishes the equivalence between the withdrawal and withholding of life-sustaining interventions and the inadequacy related to initiating or maintaining such measures in contexts where they are in disagreement with the values and care goals defined together with patients and their families. Additionally, the position statement distinguishes strictly futile treatments from potentially inappropriate treatments and elucidates their critical implications for the appropriateness of the medical decision-making process in this context. Finally, we address the issue of conscientious objection and its limits, determine that the ethical commitment to the relief of suffering should not be influenced by the decision to employ or not employ life-sustaining interventions and warn against the use of language that causes patients/families to believe that only one of the available options related to the use or nonuse of these interventions will enable the relief of suffering. lifesustaining life sustaining illnesses decisions introductionmaintenance introduction maintenance withdrawalwithholding ones guide perspective Brazil families Additionally decisionmaking making Finally limits patientsfamilies

https://doi.org/10.62675/2965-2774.20240021-en

Evaluation of glass powder in the mitigation of the alkali-silica reaction (ASR) alkalisilica alkali silica ASR (ASR
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Freitas, Taís Oliveira Gonçalves

; Dias, Gabriela Silva

; Borges, Alexandre Lopes

; Ferreira, Fernanda Giannotti da Silva

Revista IBRACON de Estruturas e Materiais

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2024, Volume 17 N. 5 elocation e17504

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A reação álcali-sílica (RAS) é um dos problemas que pode comprometer a durabilidade do concreto, uma vez que as reações químicas entre o agregado reativo e a solução porosa do concreto, em particular, sódio (Na+), potássio (K+), cálcio (Ca2+) e hidroxila (OH-) na presença de umidade, desencadeiam a expansão e fissuração dos elementos de concreto. O uso de materiais pozolânicos, como o pó de vidro finamente moído (com partículas abaixo de 75μm), para substituir parcialmente o cimento, tem sido amplamente estudado e demonstrou resultados benéficos. No entanto, devido ao fato de que o comportamento das pozolanas em relação à RAS ainda não é completamente compreendido, este trabalho avalia o efeito da incorporação de pó de vidro moído em compósitos cimentícios frente a RAS. Para isso, 8% de sílica ativa como controle, e quatro teores de pó de vidro (10, 20, 30 e 50%) foram incorporados à mistura cimentícia em substituição parcial ao cimento. Testes de expansão foram realizados de acordo com a NBR15577-4 (ABNT, 2018) em barras de argamassa usando o método de teste acelerado para avaliar a mitigação das expansões. Os resultados mostram que as expansões causadas pela RAS diminuíram com o aumento do teor de pó de vidro das misturas de cimento. Além disso, apenas o nível de 50% reduziu as expansões a um valor seguro de acordo com a norma brasileira. álcalisílica álcali (RAS concreto particular Na+, Na Na+ , (Na+) K+, K K+ (K+) Ca2+ Ca2 Ca (Ca2+ OH (OH- umidade pozolânicos 75μm, 75μm μm 75μm) cimento benéficos entanto compreendido isso 8 controle 10, 10 (10 20 3 50 NBR155774 NBR NBR15577 4 NBR15577- ABNT, ABNT (ABNT 2018 disso brasileira (Na+ (K+ (Ca2 (OH 1 (1 2 5 NBR1557 201 (Na (K (Ca ( NBR155 NBR15 NBR1

Abstract The alkali-silica reaction (ASR) is one of the problems that can compromise concrete durability, as the chemical reactions between the reactive aggregate and concrete pore solution, specifically sodium (Na+), potassium (K+), calcium (Ca2+) and hydroxyl (OH-) in the presence of moisture, trigger expansion and cracking of concrete elements. The use of pozzolanic materials, such as finely ground glass powder (particles smaller than 75μm), to partially replace cement has been widely studied and has demonstrated beneficial results. However, because the behavior of pozzolans towards ASR is not completely understood yet, this work evaluates the effect of incorporating ground glass powder into cementitious composites against ASR. To this end, 8% silica fume was used as a control admixture, and four levels of glass powder (10, 20, 30, and 50%) were incorporated into the cementitious mixture to partially replace cement. Expansion tests were carried out in accordance with NBR15577-4 (ABNT, 2018) on mortar bars using the accelerated test method to assess the mitigation of expansions. The results show that the expansions caused by ASR decreased with the increasing content of glass powder in the cement mixtures. Furthermore, only the 50% level reduced the expansions to a safe value according to the Brazilian standard. alkalisilica alkali (ASR durability solution Na+, Na Na+ , (Na+) K+, K K+ (K+) Ca2+ Ca2 Ca (Ca2+ OH (OH- moisture elements materials particles 75μm, 75μm μm 75μm) However yet end 8 admixture 10, 10 (10 20 30 50 NBR155774 NBR NBR15577 4 NBR15577- ABNT, ABNT (ABNT 2018 mixtures Furthermore standard (Na+ (K+ (Ca2 (OH 1 (1 2 3 5 NBR1557 201 (Na (K (Ca ( NBR155 NBR15 NBR1

https://doi.org/10.1590/s1983-41952024000500004

Comprehensive analysis of the HCK gene in myeloid neoplasms: Insights into biological functions, prognosis, and response to antineoplastic agents neoplasms functions prognosis
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Carvalho, Maria Fernanda Lopes

; Almeida, Bruna Oliveira de

; Bueno, Maura Lima Pereira

; Vicari, Hugo Passos

; Lima, Keli

; Rego, Eduardo Magalhães

; Roversi, Fernanda Marconi

; Machado-Neto, João Agostinho

Hematology, Transfusion and Cell Therapy

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2024, Volume 46 N. 3 Pages 273 - 282

Abstract: En | Text: En | PDF: En

Abstract Myeloid neoplasms result from molecular alterations in hematopoietic stem cells, with acute myeloid leukemia (AML) being one of the most aggressive and with a poor prognosis. Hematopoietic cell kinase (HCK) is a proto-oncogene that encodes a protein-tyrosine kinase of the Scr family, and it is highly expressed in AML. The present study investigated HCK expression in normal hematopoietic cells across myeloid differentiation stages and myeloid neoplasm patients. Within the AML cohort, we explored the impact of HCK expression on clinical outcomes and its correlation with clinical, genetic, and laboratory characteristics. Furthermore, we evaluated the association between HCK expression and the response to antineoplastic agents using ex vivo assay data from AML patients. HCK expression is higher in differentiated subpopulations of myeloid cells. High HCK expression was observed in patients with chronic myelomonocytic leukemia, chronic myeloid leukemia, and AML. In patients with AML, high levels of HCK negatively impacted overall and disease-free survival. High HCK expression was also associated with worse molecular risk groups and white blood cell count; however, it was not an independent prognostic factor. In functional genomic analyses, high HCK expression was associated with several biological and molecular processes relevant to leukemogenesis. HCK expression was also associated with sensitivity and resistance to several drugs currently used in the clinic. In conclusion, our analysis confirmed the differential expression of HCK in myeloid neoplasms and its potential association with unfavorable molecular risks in AML. We also provide new insights into HCK biological functions, prognosis, and response to antineoplastic agents. (AML prognosis (HCK protooncogene proto oncogene proteintyrosine protein tyrosine family cohort genetic characteristics Furthermore diseasefree disease free survival count however factor analyses leukemogenesis clinic conclusion functions

https://doi.org/10.1016/j.htct.2023.11.007

Sometimes, the size matters: Wing geometric morphometrics as a tool to assess domiciliation by Triatoma sordida (Stäl 1859) Sometimes matters Stäl 1859 185 18 1
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Ribeiro-Jr, Gilmar

; Reis, Jamylle

; Vaccarezza, Fernanda

; Silva, Amanda Catariny de Oliveira

; Lanza, Fernanda Cardoso

; Miranda, Diego Lopes Paim

; Gurgel-Gonçalves, Rodrigo

; Reis, Mitermayer Galvão dos

Revista da Sociedade Brasileira de Medicina Tropical

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2024, Volume 57 elocation e00709-2024

Abstract: En | Text: En | PDF: En

ABSTRACT Background: Domiciliation by Triatoma sordida is a public health concern in South America. This study aimed to evaluate the morphometric changes in the domestic and peridomestic populations of T. sordida. Methods: Specimen hemelytra were mounted, digitized, and processed for geometric morphometric analyses. Results: The specimens captured in houses were smaller than those captured in peridomiciles. A large size reduction effect was observed in female peridomicile populations compared with female house populations. Conclusions: T. sordida house populations were smaller than peridomestic populations. Wing geometric morphometry can be used as a tool to indicate T. sordida domiciliation. Background America T Methods mounted digitized analyses Results peridomiciles Conclusions domiciliation

https://doi.org/10.1590/0037-8682-0516-2023

Tree thinning affects the physicochemical characteristics and bioactive compounds in ‘Barton’ and ‘Melhorada’ pecan cultivars ‘Barton Barton ‘Melhorada Melhorada
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Hoffmann, Jessica Fernanda

; Crizel, Rosane Lopes

; Siebeneichler, Tatiane Jéssica

; Foscarini, Stefany Cristina

; Silva, Tamires de Oliveira Duarte da

; Ferreira, Cristiano Dietrich

; Carvalho, Ivan Ricardo

; Hellwig, Cristiano Geremias

; Martins, Carlos Roberto

Ciência e Agrotecnologia

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2024, Volume 48 elocation e005924

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO A produção e consumo de nozes vem aumentando nos últimos tempos, e com isso, há de se estudar as melhores práticas de produção, que aumentem a quantidade produzida e favoreçam ou mantenham os compostos bioativos presentes. Nesse sentido, esse trabalho teve como objetivo verificar a interferência do desbaste de plantas nas características físico-químicas e compostos bioativos da noz-pecã nas condições de Santa Rosa, Rio Grande do Sul. Para isso, as plantas foram submetidas a dois tipos de manejo: com desbaste e sem desbaste de plantas e os frutos foram avaliados quanto a características físicas (tamanho, peso e cor) e químicas (composição físico-química, estabilidade oxidativa, perfil de ácidos graxos e tocoferóis). O desbaste das plantas aumentou o tamanho e a massa das nozes, assim como, reduziu o índice de acidez e peróxidos e aumentou o conteúdo de γ-tocoferol. As demais avaliações de qualidade não foram alteradas significativamente com o desbaste das plantas. tempos isso presentes sentido físicoquímicas físico nozpecã noz pecã Rosa Sul manejo tamanho, (tamanho cor composição físicoquímica, físicoquímica química, química físico-química oxidativa tocoferóis. tocoferóis . tocoferóis) γtocoferol. γtocoferol γ tocoferol. tocoferol γ-tocoferol

ABSTRACT The production and consumption of pecan nuts have been on the rise in recent times, which renders it necessary to study the best production practices to increase the yield, enhance the flavor, and maintain the bioactive components in the final product. The present study, therefore, aimed to verify the effects of tree thinning on the physicochemical characteristics and bioactive components in pecan under the cultivation conditions of Santa Rosa, Rio Grande do Sul. The pecan plants were submitted to two types of management - with thinning and without thinning, following which the fruits were evaluated for physical (size, weight, and color) and chemical (physicochemical composition, oxidative stability, fatty acid profile, and tocopherols) attributes. The results revealed that the thinning of plants increased the size and mass of both nuts and kernels while reducing the acid content and peroxides in the kernels and increasing the γ-tocopherol levels. The other quality evaluations did not reveal any significant alterations after plant thinning. times yield flavor product therefore Rosa Sul size, (size weight color composition stability profile tocopherols attributes γtocopherol γ tocopherol levels

https://doi.org/10.1590/1413-7054202448005924

Transcriptomics analysis identified ezrin as a potential druggable target in cervical and gastric cancer cells
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Carvalho, Maria Fernanda Lopes

; Calicchio, Carolina Santana

; Almeida, Bruna Oliveira de

; Miranda, Livia Bassani Lins de

; Silva, Jean Carlos Lipreri da

; Lima, Keli

; Machado-Neto, João Agostinho

Clinics

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2024, Volume 79 elocation 100422

Abstract: En | Text: En | PDF: En

Abstract Objective: Cancer genomics and transcriptomics studies have provided a large volume of data that enables to test of hypotheses based on real data from cancer patients. Ezrin (encoded by the EZR gene) is a highly expressed protein in cancer that contributes to linking the actin cytoskeleton to the cell membrane and signal transduction pathways involved in oncogenesis and disease progression. NSC305787 is a pharmacological ezrin inhibitor with potential antineoplastic effects. In the present study, the authors prospected EZR mRNA levels in a pan-cancer analysis and identified potential cancers that could benefit from anti-EZR therapies. Methods: This study analyzed TCGA data for 32 cancer types, emphasizing cervical squamous cell carcinoma and stomach adenocarcinoma. It investigated the impact of EZR transcript levels on clinical outcomes and identified differentially expressed genes. Cell lines were treated with NSC305787, and its effects were assessed through various cellular and molecular assays. Results: EZR mRNA levels are highly expressed, and their expression is associated with biologically relevant molecular processes in cervical squamous carcinoma and stomach adenocarcinoma. In cellular models of cervical and gastric cancer, NSC305787 reduces cell viability and clonal growth (p < 0.05). Molecular analyses indicate that the pharmacological inhibition of EZR induces molecular markers of cell death and DNA damage, in addition, to promoting the expression of genes associated with apoptosis and inhibiting the expression of genes related to survival and proliferation. Conclusion: The present findings provide promising evidence that ezrin may be a molecular target in the treatment of cervical and gastric carcinoma. Objective patients encoded gene progression NSC NSC30578 pancancer pan antiEZR anti therapies Methods 3 types adenocarcinoma assays Results p 0.05. 005 0.05 . 0 05 0.05) damage addition proliferation Conclusion NSC3057 00 0.0 NSC305 0. NSC30 NSC3

https://doi.org/10.1016/j.clinsp.2024.100422

10.

Variability and functional characterization of the Phakopsora pachyrhizi Egh16-like effectors Egh16like Eghlike Egh16 like Egh Egh1
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Castanho, Fernanda Machado

; Costa, Beatriz Lorena Comin da

; Abe, Valéria Yukari

; Yokoyama, Alessandra

; Darben, Luana Mieko

; Oliveira, Liliane Santana

; Ferreira, Everton Geraldo Capote

; Lopes, Ivani de Oliveira Negrão

; Carvalho, Mayra Costa da Cruz Gallo de

; Balbi-Peña, Maria Isabel

; Marcelino-Guimarães, Francismar Corrêa

Genetics and Molecular Biology

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2024, Volume 47 N. 3 elocation e20230192

Abstract: En | Text: En | PDF: En

Abstract Effector proteins in Phakopsora pachyrhizi (Pp), the causative agent of Asian Soybean rust, are involved in the infection process. A previous study identified a rust effector Egh16-like family based expression profile during the interaction with soybean. Herein, we scrutinized available the Pp genomes to validate the predicted Egh16-like family of Pp and identify new family members. We described 22 members of the Egh16-like gene family in the Pp MT2006 genome and 18 in the UFV02 and K8108 genomes, highlighting a family expansion. Family members have a small signal peptide, conserved cysteine-rich R/Y/FxC motifs in the C-terminal region, and a virulence-related Egh16-like domain and were able to suppress PTI related responses in Benthamiana. Phylogenetic analysis placed the family members into eight clusters, with members induced during the early stages of rust infection. Members of clusters VI and VII are present in different copy numbers in Pp genomes and suppressed PAMP-related responses. Pp, , (Pp) process Egh16like Eghlike Egh16 like Egh soybean Herein 2 MT MT200 1 UFV UFV0 K K810 expansion peptide cysteinerich cysteine rich RYFxC R Y FxC Cterminal C terminal region virulencerelated virulence Benthamiana PAMPrelated PAMP (Pp Egh1 MT20 K81 MT2 K8

https://doi.org/10.1590/1678-4685-gmb-2023-0192

11.

Root Temperature Variation during Gutta-Percha Removal Using Stainless Steel and NiTi Instruments GuttaPercha Gutta Percha
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Suassuna, Fernanda Clotilde Mariz

; Amorim, Ana Marly Araújo Maia

; Melo, Saulo Leonardo Sousa

; Silva, Diego Filipe Bezerra

; Lopes, Layrlla Kateriny Moura Oliveira

; Bento, Patrícia Meira

; Melo, Daniela Pita de

Pesquisa Brasileira em Odontopediatria e Clínica Integrada

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2024, Volume 24 elocation e230021

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: To assess the temperature variation of gutta-percha removal with stainless steel and two NiTi instruments using infrared thermography and thermocouples. Material and Methods: 45 single-rooted teeth were divided into three groups (n = 15) according to the following gutta-percha removal instruments: Largo Peeso (L), Protaper Retreatment (PR), and Reciproc (R). Thermal analysis was conducted using a FLIR T650sc infrared thermography camera and three thermocouples. For infrared thermography assessment, the infrared camera was programmed to acquire thermograms every 15 seconds before the gutta-percha removal started until temperature normalization. Root temperature was assessed in the thermograms using FLIR tools software v6.4 with the straight-line tool along the long axis of the tooth and in the cervical, middle, and apical thirds of each tooth. The temperature from the thermocouples was recorded and registered for each root third. Inferential statistical analysis Kruskal-Wallis and post hoc Tukey tests were used. Results: For the infrared thermography camera, the highest median temperature value was found 15 seconds after guttapercha removal for the L technique (20.3°C), which presented the highest temperatures at all studied times. For thermocouples, the highest temperature was found in the middle third during gutta-percha removal with L (20.7°C). PR and R presented similar patterns of root temperature. Conclusion: Stainless-steel L temperature reaches values above 10°C; however, the exposure time was too short to cause injuries to the periodontium. Objective gutta percha Methods 4 singlerooted single rooted n L, , (L) PR, (PR) R. . (R) Tsc T sc assessment 1 normalization v64 v v6 v6. straightline straight line cervical KruskalWallis Kruskal Wallis used Results 20.3°C, 203C C 20.3°C 20 3 (20.3°C) times 20.7°C. 207C 20.7°C 7 (20.7°C) Conclusion Stainlesssteel Stainless 10°C 10C 10 however periodontium (L (PR (R 2 (20.3°C (20.7°C

https://doi.org/10.1590/pboci.2024.091

12.

Diretriz Brasileira sobre a Saúde Cardiovascular no Climatério e na Menopausa – 2024 202 20 2
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Oliveira, Gláucia Maria Moraes de

; Almeida, Maria Cristina Costa de

; Arcelus, Carolina María Artucio

; Neto Espíndola, Larissa

; Rivera, Maria Alayde Mendonça

; Silva-Filho, Agnaldo Lopes da

; Marques-Santos, Celi

; Fernandes, César Eduardo

; Albuquerque, Carlos Japhet da Matta

; Freire, Claudia Maria Vilas

; Izar, Maria Cristina de Oliveira

; Costa, Maria Elizabeth Navegantes Caetano

; Castro, Marildes Luiza de

; Lemke, Viviana de Mello Guzzo

; Lucena, Alexandre Jorge Gomes de

; Brandão, Andréa Araujo

; Macedo, Ariane Vieira Scarlatelli

; Polanczyk, Carisi Anne

; Lantieri, Carla Janice Baister

; Nahas, Eliana Petri

; Alexandre, Elizabeth Regina Giunco

; Campana, Erika Maria Gonçalves

; Bragança, Érika Olivier Vilela

; Colombo, Fernanda Marciano Consolim

; Barbosa, Imara Correia de Queiroz

; Rivera, Ivan Romero

; Kulak, Jaime

; Moura, Lidia Ana Zytynski

; Pompei, Luciano de Mello

; Baccaro, Luiz Francisco Cintra

; Barbosa, Marcia Melo

; Rodrigues, Marcio Alexandre Hipólito

; Albernaz, Marco Aurelio

; Decoud, Maria Sotera Paniagua de

; Paiva, Maria Sanali Moura de Oliveira

; Sanchez-Zambrano, Martha Beatriz

; Campos, Milena dos Santos Barros

; Acevedo, Monica

; Ramirez, Monica Susana

; Souza, Olga Ferreira de

; Medeiros, Orlando Otávio de

; Carvalho, Regina Coeli Marques de

; Machado, Rogerio Bonassi

; Silva, Sheyla Cristina Tonheiro Ferro da

; Rodrigues, Thais de Carvalho Vieira

; Avila, Walkiria Samuel

; Costa-Paiva, Lucia Helena Simões da

; Wender, Maria Celeste Osorio

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 7 elocation e20240478

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.36660/abc.20240478

13.

Brazilian Guideline on Menopausal Cardiovascular Health – 2024 202 20 2
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Oliveira, Gláucia Maria Moraes de

; Almeida, Maria Cristina Costa de

; Arcelus, Carolina María Artucio

; Espíndola Neto, Larissa

; Rivera, Maria Alayde Mendonça

; Silva-Filho, Agnaldo Lopes da

; Marques-Santos, Celi

; Fernandes, César Eduardo

; Albuquerque, Carlos Japhet da Matta

; Freire, Claudia Maria Vilas

; Izar, Maria Cristina de Oliveira

; Costa, Maria Elizabeth Navegantes Caetano

; Castro, Marildes Luiza de

; Lemke, Viviana de Mello Guzzo

; Lucena, Alexandre Jorge Gomes de

; Brandão, Andréa Araujo

; Macedo, Ariane Vieira Scarlatelli

; Polanczyk, Carisi Anne

; Lantieri, Carla Janice Baister

; Nahas, Eliana Petri

; Alexandre, Elizabeth Regina Giunco

; Campana, Erika Maria Gonçalves

; Bragança, Érika Olivier Vilela

; Colombo, Fernanda Marciano Consolim

; Barbosa, Imara Correia de Queiroz

; Rivera, Ivan Romero

; Kulak, Jaime

; Moura, Lidia Ana Zytynski

; Pompei, Luciano de Mello

; Baccaro, Luiz Francisco Cintra

; Barbosa, Marcia Melo

; Rodrigues, Marcio Alexandre Hipólito

; Albernaz, Marco Aurelio

; Decoud, Maria Sotera Paniagua de

; Paiva, Maria Sanali Moura de Oliveira

; Sanchez-Zambrano, Martha Beatriz

; Campos, Milena dos Santos Barros

; Acevedo, Monica

; Ramirez, Monica Susana

; Souza, Olga Ferreira de

; Medeiros, Orlando Otávio de

; Carvalho, Regina Coeli Marques de

; Machado, Rogerio Bonassi

; Silva, Sheyla Cristina Tonheiro Ferro da

; Rodrigues, Thais de Carvalho Vieira

; Avila, Walkiria Samuel

; Costa-Paiva, Lucia Helena Simões da

; Wender, Maria Celeste Osorio

Revista Brasileira de Ginecologia e Obstetrícia

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2024, Volume 46 elocation e-rbgo100

Abstract: En | Text: En | PDF: En

https://doi.org/10.61622/rbgo/2024rbgo100

14.

Vaccine coverage by social strata in state capitals in the Brazilian Midwest region: a household survey of children born in 2017 and 2018 region 201 20 2
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Lima, Jaqueline Costa

; Garcia, Érica Marvila

; Oliveira, Sandra Maria do Valle Leone de

; Araújo, Wildo Navegantes de

; Lopes, Emmanuela Maria de Freitas

; Teles, Sheila Araújo

; Caetano, Karlla Antonieta Amorim

; Teixeira, Ana Izabel Passarela

; Alves, Bárbara Manuella Cardoso Sodré

; França, Ana Paula

; Moraes, José Cássio de

; Domingues, Carla Magda Allan Santos

; Silva, Adriana Ilha da

; Ramos Jr., Alberto Novaes

; França, Ana Paula

; Oliveira, Andrea de Nazaré Marvão

; Boing, Antonio Fernando

; Domingues, Carla Magda Allan Santos

; Oliveira, Consuelo Silva de

; Maciel, Ethel Leonor Noia

; Guibu, Ione Aquemi

; Mirabal, Isabelle Ribeiro Barbosa

; Barbosa, Jaqueline Caracas

; Lima, Jaqueline Costa

; Moraes, José Cássio de

; Luhm, Karin Regina

; Caetano, Karlla Antonieta Amorim

; Lima, Luisa Helena de Oliveira

; Antunes, Maria Bernadete de Cerqueira

; Teixeira, Maria da Gloria

; Teixeira, Maria Denise de Castro

; Borges, Maria Fernanda de Sousa Oliveira

; Queiroz, Rejane Christine de Sousa

; Gurgel, Ricardo Queiroz

; Barata, Rita Barradas

; Azevedo, Roberta Nogueira Calandrini de

; Oliveira, Sandra Maria do Valle Leone de

; Teles, Sheila Araújo

; Gama, Silvana Granado Nogueira da

; Mengue, Sotero Serrate

; Simões, Taynãna César

; Nascimento, Valdir

; Araújo, Wildo Navegantes de

Epidemiologia e Serviços de Saúde

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2024, Volume 33 N. spe2 elocation e20231308

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo Analisar a cobertura vacinal completa em nascidos vivos em 2017 e 2018, nas capitais da região Centro-Oeste do Brasil, segundo estratos sociais. Métodos Inquérito domiciliar de base populacional com amostragem por conglomerados. Analisou-se a cobertura vacinal completa em crianças aos 12 e 24 meses de idade e os fatores sociodemográficos. Resultados Foram analisadas 5.715 crianças. A cobertura completa aos 12 meses de idade foi 67,9% (IC95% 65,4;70,4) e aos 24 meses de idade foi 48,2% (IC95% 45,3;51,1). A maior cobertura foi da vacina pneumococo (91,3%) e a pior da segunda dose da vacina rotavírus (74,2%). Em Campo Grande, nenhuma vacina alcançou cobertura acima de 90%, destacando-se as vacinas BCG (82,9%) e hepatite B (82,1%). Campo Grande e Brasília tiveram piores coberturas vacinais no estrato social alto (24 meses de idade). Conclusão A cobertura vacinal na região Centro-Oeste foi inferior a 80%, abaixo da meta preconizada e associada com fatores socioeconômicos. 201 2018 CentroOeste Centro Oeste Brasil sociais conglomerados Analisouse Analisou se 1 2 sociodemográficos 5715 5 715 5.71 679 67 9 67,9 IC95% IC95 IC (IC95 65,470,4 654704 65,4 70,4 65 4 70 65,4;70,4 482 48 48,2 45,351,1. 453511 45,3 51,1 . 45 3 51 45,3;51,1) 91,3% 913 91 (91,3% 74,2%. 742 74,2% 74 (74,2%) 90 90% destacandose destacando 82,9% 829 82 (82,9% 82,1%. 821 82,1% (82,1%) (2 idade. idade) 80 80% socioeconômicos 20 571 71 5.7 6 67, IC9 (IC9 470 65,470, 65470 654 65, 704 70, 7 65,4;70, 48, 351 45,351,1 45351 453 45, 511 51, 45,3;51,1 91,3 (91,3 74,2 (74,2% 82,9 8 (82,9 82,1 (82,1% ( 57 5. (IC 47 65,470 6547 65,4;70 35 45,351, 4535 45,3;51, 91, (91, 74, (74,2 82, (82, (82,1 65,47 65,4;7 45,351 45,3;51 (91 (74, (82 65,4; 45,35 45,3;5 (9 (74 (8 45,3; (7

ABSTRACT Objective To analyze full vaccination coverage in live births in 2017 and 2018 in the capitals of the Midwest region of Brazil, according to social strata. Methods Population-based household survey with cluster sampling. Full coverage in children at 12 and 24 months of age and sociodemographic factors were analyzed. Results 5,715 children were analyzed. Full coverage at 12 months of age was 67.9% (95%CI 65.4;70.4), while at 24 months it was 48.2% (95%CI 45.3;51.1). Pneumococcal vaccine had the highest vaccination coverage (91.3%), while the second dose of rotavirus vaccine had the lowest (74.2%). In Campo Grande, no vaccine reached coverage above 90%, with BCG (82.9%) and hepatitis B (82.1%) standing out. Campo Grande and Brasília had the worst vaccination coverage in the high social stratum (24 months of age). Conclusion Vaccination coverage in the Midwest was below 80%, falling short of the recommended target and associated with socioeconomic factors. 201 Brazil strata Populationbased Population based sampling 1 2 analyzed 5715 5 715 5,71 679 67 9 67.9 95%CI 95CI CI 95 65.470.4, 654704 65.4 70.4 , 65 4 70 65.4;70.4) 482 48 48.2 45.351.1. 453511 45.3 51.1 . 45 3 51 45.3;51.1) 91.3%, 913 91.3% 91 (91.3%) 74.2%. 742 74.2% 74 (74.2%) 90 90% 82.9% 829 82 (82.9% 82.1% 821 (82.1% out (2 age. age) 80 80% 20 571 71 5,7 6 67. 470 65.470.4 65470 654 65. 704 70. 7 65.4;70.4 48. 351 45.351.1 45351 453 45. 511 51. 45.3;51.1 91.3 (91.3% 74.2 (74.2% 82.9 8 (82.9 82.1 (82.1 ( 57 5, 47 65.470. 6547 65.4;70. 35 45.351. 4535 45.3;51. 91. (91.3 74. (74.2 82. (82. 65.470 65.4;70 45.351 45.3;51 (91. (74. (82 65.47 65.4;7 45.35 45.3;5 (91 (74 (8 65.4; 45.3; (9 (7

resumen está disponible en el texto completo

https://doi.org/10.1590/s2237-96222024v33e20231308.especial2.en

15.

Prática e incentivo paterno a dietas podem predizer comportamentos de risco relacionados a transtornos alimentares? Uma revisão sistemática alimentares
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Dunker, Karin Louise Lenz

; Portella, Laís Lopes

; Haddad, Lívia Kalil

; Nobrega, Fernanda Gramigna de

; Latorre, Fernanda Andrade de Oliveira

; Pascoal, Melissa

; Grigolon, Ruth Bartelli

Jornal Brasileiro de Psiquiatria

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mar 2023, Volume 72 N. 1 Pages 54 - 62

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivos: Avaliar se a modelagem paterna, quanto à prática e/ou ao incentivo a dietas, pode predizer comportamentos de risco relacionados a transtornos alimentares (TAs) em crianças e adolescentes. Métodos: Foi realizada uma revisão sistemática dos estudos publicados até junho de 2022, disponíveis nas bases de dados indexadas — como PubMed, Biblioteca Virtual de Saúde, SciELO e Cochrane Library. Estudos transversais e longitudinais em línguas portuguesa, espanhola e inglesa foram incluídos e avaliados quanto ao risco de viés de acordo com a NewCastle – Ottawa Quality Assessment Scale . Resultados: Quatorze estudos foram considerados na revisão. A maioria deles é transversal (71,4%), proveniente dos Estados Unidos e de países europeus (57,1%), além de apresentar baixo risco de viés (85,7%). Grande parte dos trabalhos encontrou associações entre o incentivo a dietas por parte dos pais (modelagem direta) e comportamentos de risco em crianças e adolescentes, como o uso de métodos de controle de peso, a insatisfação corporal e a restrição alimentar. Poucos estudos relacionaram o hábito de o pai fazer dieta (modelagem indireta) com esses comportamentos. Conclusões: Os dados embasam a ideia de que a modelagem direta, ou seja, o incentivo verbal ao uso de dietas, pode ser muito danosa, principalmente em indivíduos que têm preocupações excessivas com peso e alimentação. Futuras pesquisas são necessárias para avaliar o impacto das práticas alimentares parentais e o desenvolvimento de possíveis ações de prevenção a problemas relacionados ao peso. Objetivos paterna eou TAs (TAs adolescentes Métodos 2022 PubMed Saúde Library portuguesa Resultados 71,4%, 714 71,4% , 71 4 (71,4%) 57,1%, 571 57,1% 57 1 (57,1%) 85,7%. 857 85,7% 85 7 (85,7%) direta alimentar indireta Conclusões seja danosa alimentação 202 71,4 (71,4% 57,1 5 (57,1% 85,7 8 (85,7% 20 71, (71,4 57, (57,1 85, (85,7 2 (71, (57, (85, (71 (57 (85 (7 (5 (8 (

ABSTRACT Objectives: To assess whether parental modeling, regarding the practice and/or encouragement of diets, can predict risk behaviors related to eating disorders (EDs) in children and adolescents. Methods: A systematic review of studies published until June 2022, available in indexed databases – such as PubMed, Virtual Health Library, SciELO and Cochrane Library, was carried out. Cross-sectional and longitudinal studies in Portuguese, Spanish and English were included and assessed for risk of bias according to the NewCastle – Ottawa Quality Assessment Scale. Results: Fourteen studies were considered in the review. Most of them are cross-sectional (71.4%), coming from the United States and European countries (57.1%), in addition to presenting a low risk of bias (85.7%). Most of the studies found associations between parental encouragement of diets (direct modeling) and risk behaviors in children and adolescents, such as the use of weight control methods, body dissatisfaction and food restriction. Few studies have related the father’s habit of dieting (indirect modeling) with these behaviors. Conclusions: Data support the idea that direct modeling, that is, verbal encouragement to use diets, can be very harmful, especially to individuals who are excessively concerned about weight and food. Future research is needed to assess the impact of parental eating practices and the development of possible actions to prevent weight-related problems. Objectives modeling andor or EDs (EDs adolescents Methods 2022 PubMed Library out Crosssectional Cross sectional Portuguese Scale Results crosssectional cross 71.4%, 714 71.4% , 71 4 (71.4%) 57.1%, 571 57.1% 57 1 (57.1%) 85.7%. 857 85.7% . 85 7 (85.7%) methods restriction fathers father s indirect Conclusions harmful weightrelated problems 202 71.4 (71.4% 57.1 5 (57.1% 85.7 8 (85.7% 20 71. (71.4 57. (57.1 85. (85.7 2 (71. (57. (85. (71 (57 (85 (7 (5 (8 (

https://doi.org/10.1590/0047-2085000000405

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