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Resumo Objetivou-se realizar uma análise espacial da taxa de mortalidade hospitalar (TMH) por síndrome respiratória aguda grave (SRAG) atribuída à COVID-19 em crianças e adolescentes no Brasil no período de 2020 a 2021. Utilizou-se o método de cluster para agrupar as unidades federativas (UFs) com base na TMH. Em 2020, clusters com altas TMHs foram formados por UFs Norte/Nordeste. Em 2021, houve redução na TMH. Os clusters com maiores taxas permaneceram na região N/NE. Diferenças regionais foram observadas nas TMHs. Os achados podem refletir as desigualdades sociais e o acesso à atenção hospitalar, principalmente na faixa etária de menores de 1 ano pela gravidade da doença neste grupo.

Abstract The objective was to perform a spatial analysis of the hospital mortality rate (HMR) due to severe acute respiratory syndrome (SARS) attributed to COVID-19 among children and adolescents in Brazil from 2020 to 2021. A cluster method was used to group federal units (FUs) based on HMR. In 2020, clusters with high HMRs were formed by north/northeast FUs. In 2021, there was a reduction in HMR. Clusters with higher rates remained in the N/NE region. Regional differences were observed in the HMR. The findings may reflect social inequalities and access to hospital care, especially in the under 1-year-old age group due to the severity of the disease in this group.

https://doi.org/10.1590/1413-81232024291.19892022

Spatial analysis of hospital-related mortality due to COVID-19 among children and adolescents in Brazil
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Costa, Silmery da Silva Brito

; Branco, Maria dos Remédios Freitas Carvalho

; Pereira, Andressa Rocha

; Costa, Elisa Miranda

; Araújo, Mayra Sharlenne Moraes

; Oliveira, Daniel Cavalcante de

; Oliveira, Bruno Luciano Carneiro Alves de

; Rangel, Maurício Eduardo Salgado

; Tonello, Aline Sampieri

; Lopes, Denise Ailine Monteiro

; Pinheiro, Vanessa Vieira

; Câmara, Ana Patricia Barros

; Santos, Alcione Miranda dos

; Vasconcelos, Vitor Vieira

Ciência & Saúde Coletiva

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2024, Volume 29 N. 1 elocation e19892022

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1413-81232024291.19892022

Contamination of equipment and surfaces in the operating room anesthesia workspace: a cross-sectional study workspace crosssectional cross sectional
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Macedo, Carlos Eduardo

; Ferreira, Adriano Menis

; Barcelos, Larissa da Silva

; Alvim, André Luiz Silva

; Carneiro, Liliane Moretti

; Martins, Sandro Rogério

; Andrade, Denise de

; Rigotti, Marcelo Alessandro

; Gasques, Ruberval Peres

; Silva Junior, Vanderlei Amaro da

; Oliveira, Layze Braz de

; Carvalho, Herica Emilia Félix de

; Sousa, Alvaro Francisco Lopes de

Sao Paulo Medical Journal

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2024, Volume 142 N. 4 elocation e2023177

Abstract: En | Text: En | PDF: En

ABSTRACT BACKGROUND: Contamination of the breathing circuit and medication preparation surface of an anesthesia machine can increase the risk of cross-infection. OBJECTIVE: To evaluate the contamination of the anesthetic medication preparation surface, respiratory circuits, and devices used in general anesthesia with assisted mechanical ventilation. DESIGN AND SETTING: Cross-sectional, quantitative study conducted at the surgical center of a philanthropic hospital, of medium complexity located in the municipality of Três Lagoas, in the eastern region of the State of Mato Grosso do Sul. METHODS: Eighty-two microbiological samples were collected from the breathing circuits. After repeating the samples in different culture media, 328 analyses were performed. RESULTS: A higher occurrence of E. coli, Enterobacter spp., Pseudomonas spp., Staphylococcus aureus, and Streptococcus pneumoniae (P < 0.001) were observed. Variations were observed depending on the culture medium and sample collection site. CONCLUSION: The study findings underscore the inadequate disinfection of the inspiratory and expiratory branches, highlighting the importance of stringent cleaning and disinfection of high-touch surfaces. BACKGROUND crossinfection. crossinfection cross infection. infection cross-infection OBJECTIVE circuits ventilation SETTING Crosssectional, Crosssectional Cross sectional, sectional Cross-sectional hospital Lagoas Sul METHODS Eightytwo Eighty two media 32 performed RESULTS E coli spp spp. aureus P 0.001 0001 0 001 site CONCLUSION branches hightouch high touch surfaces 3 0.00 000 00 0.0 0.

https://doi.org/10.1590/1516-3180.2023.0177.r1.291123

The path to elimination: FEBRASGO 2023's targeted strategies against cervical cancer in Brazil elimination 2023s s 2023 202 20 2
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da Silva Filho, Agnaldo Lopes

; Roteli-Martins, Cecilia Maria

; de Góis Speck, Neila Maria

; de Carvalho, Newton Sérgio

; Cândido, Eduardo Batista

; Teixeira, Júlio César

Revista Brasileira de Ginecologia e Obstetrícia

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2024, Volume 46 elocation e-rbgoedt2

Abstract: En | Text: En | PDF: En

https://doi.org/10.61622/rbgo/2024edt02

Beyond the diagnosis: gender disparities in the social and emotional impact of cancer diagnosis
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Praça, Mariana Seabra Leite

; Sousa, Frederico Timm Rodrigues de

; Cândido, Eduardo Batista

; Lamaita, Rívia Mara

; Wender, Maria Celeste Osório

; Silva Filho, Agnaldo Lopes

Revista da Associação Médica Brasileira

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2024, Volume 70 Suppl. 1 elocation e2024S115

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/1806-9282.2024s115

Spatial analysis of hospital-related mortality due to COVID-19 among children and adolescents in Brazil hospitalrelated hospital related COVID19 COVID 19 COVID-1 COVID1 1 COVID-
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Costa, Silmery da Silva Brito

; Branco, Maria dos Remédios Freitas Carvalho

; Pereira, Andressa Rocha

; Costa, Elisa Miranda

; Araújo, Mayra Sharlenne Moraes

; Oliveira, Daniel Cavalcante de

; Oliveira, Bruno Luciano Carneiro Alves de

; Rangel, Maurício Eduardo Salgado

; Tonello, Aline Sampieri

; Lopes, Denise Ailine Monteiro

; Pinheiro, Vanessa Vieira

; Câmara, Ana Patricia Barros

; Santos, Alcione Miranda dos

; Vasconcelos, Vitor Vieira

Ciência & Saúde Coletiva

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2024, Volume 29 N. 1 elocation e19892022

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232024291.19892022

SÍNTESE, FOTORREATIVIDADE E INTERAÇÃO COM DNA DE UM NOVO COMPLEXO DE RUTÊNIO PROTÓTIPO PARA O DESENVOLVIMENTO DE AGENTES FOTOQUIMIOTERAPÊUTICOS SÍNTESE
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Pereira, Walysson Gomes

; Martins, Patrícia Helenita Rocha

; Martins Filho, Paulo Eduardo Cavalcanti

; Paulo, Tércio Freitas

; Diógenes, Izaura Cirino Nogueira

; Sousa, Eduardo Henrique Silva

; Lopes, Luiz Gonzaga de França

Química Nova

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2024, Volume 47 N. 6 elocation e-20240008

Abstract: Pt | Text: Pt | PDF: Pt

A new ruthenium polypyridine complex, cis-[Ru(bpy)2(1-meimN)(4-pyCHO)](PF6)2 (WP1), where 1-meimN and pyCHO are the ligands 1-methylimidazole and 4-pyridinecarboxaldehyde, respectively, was prepared as a prototype for use in phototherapeutic process. This compound was characterized by electronic absorption in UV-Visible, FTIR, 1H and 13C NMR, cyclic voltammetry, besides DFT that supported its molecular structure. The compound WP1 was photoreactive, where blue or green light promoted the release of 4-pyCHO ligand. Additionally, this compound was able to interact with DNA, mainly through electrostatic interactions showing photoinduced nuclease activity. There is also photoproduction of superoxide ions using blue or green light suggesting a route for DNA damage. These promising results opened new opportunities for the potential use of this system and analogues as phototherapeutic agents, which is an ongoing study in our lab. complex cisRubpy21meimN4pyCHOPF62 cisRubpymeimNpyCHOPF cis Ru bpy 2 1 meimN 4 PF6 PF cis-[Ru(bpy)2(1-meimN)(4-pyCHO)](PF6) WP1, WP , (WP1) 1meimN 1methylimidazole methylimidazole 4pyridinecarboxaldehyde, 4pyridinecarboxaldehyde pyridinecarboxaldehyde pyridinecarboxaldehyde, 4-pyridinecarboxaldehyde respectively process UVVisible, UVVisible UV Visible, Visible UV-Visible FTIR H C NMR voltammetry structure photoreactive 4pyCHO ligand Additionally activity damage agents lab cisRubpy pyCHOPF cisRubpy21meimN4pyCHOPF6 cis-[Ru(bpy)2(1-meimN)(4-pyCHO)](PF6 (WP1 cisRubpy21meimN4pyCHOPF cis-[Ru(bpy)2(1-meimN)(4-pyCHO)](PF (WP

https://doi.org/10.21577/0100-4042.20240008

Metabolic and ultrastructural renal changes in adult Wistar rats fed by a cafeteria diet
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Santos, Priscila Fernandes dos

; Souza, Diogo Benchimol de

; Torres, Eduardo José Lopes

; Costa, Waldemar Silva

; Sampaio, Francisco José Barcellos

; Gregorio, Bianca Martins

Acta Cirúrgica Brasileira

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2024, Volume 39 elocation e392224

Abstract: En | Text: En | PDF: En

ABSTRACT Purpose: To evaluate, by quantitative and qualitative methods, the glomerular ultrastructure in Wistar rats fed a cafeteria diet. Methods: Male Wistar rats were divided into two groups at 21 days of age: control (C, n = 10) and cafeteria diet (CAF, n = 8). The animals were followed up until 5 months of age, followed by euthanasia. The blood, kidneys, and fat deposits––epididymal, retroperitoneal, and subcutaneous––were extracted and analyzed. Data were analyzed by Student’s t test, and p < 0.05 was considered statistically significant. Results: The cafeteria diet promoted glucose intolerance, hyperglycemia (p < 0.0001), and deposition of retroperitoneal fat (p < 0.005). Scanning electron microscopy revealed that the length of the foot process was similar in both groups. The quantitative analyses by transmission electron microscopy revealed that the cafeteria diet reduced the thickness of the glomerular basement membrane (p < 0.05). Conclusions: The intake of lipids and simple carbohydrates were found to be associated with alteration in the glomerular ultrastructure. However, more studies are needed to evaluate not only the effects of high-protein and high-fat diets on components of the glomerular filtration barrier, but also renal physiology. Purpose methods Methods 2 age C, C (C 10 CAF, CAF (CAF 8. 8 . 8) euthanasia blood kidneys depositsepididymal deposits epididymal deposits––epididymal subcutaneouswere subcutaneous Students Student s test 005 0 05 0.0 significant Results intolerance 0.0001, 00001 0.0001 , 0001 0.0001) 0.005. 0005 0.005 0.005) 0.05. 0.05) Conclusions However highprotein high protein highfat barrier physiology 1 00 0. 0000 0.000 000 0.00

https://doi.org/10.1590/acb392224

II Brazilian Society of Rheumatology consensus for lupus nephritis diagnosis and treatment
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Reis-Neto, Edgard Torres dos

; Seguro, Luciana Parente Costa

; Sato, Emília Inoue

; Borba, Eduardo Ferreira

; Klumb, Evandro Mendes

; Costallat, Lilian Tereza Lavras

; Medeiros, Marta Maria das Chagas

; Bonfá, Eloisa

; Araújo, Nafice Costa

; Appenzeller, Simone

; Montandon, Ana Carolina de Oliveira e Silva

; Yuki, Emily Figueiredo Neves

; Teixeira, Roberto Cordeiro de Andrade

; Telles, Rosa Weiss

; Egypto, Danielle Christinne Soares do

; Ribeiro, Francinne Machado

; Gasparin, Andrese Aline

; Araujo Junior, Antonio Silaide de

; Neiva, Cláudia Lopes Santoro

; Calderaro, Debora Cerqueira

; Monticielo, Odirlei Andre

Advances in Rheumatology

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2024, Volume 64 elocation 48

Abstract: En | Text: En | PDF: En

Abstract Objective To develop the second evidence-based Brazilian Society of Rheumatology consensus for diagnosis and treatment of lupus nephritis (LN). Methods Two methodologists and 20 rheumatologists from Lupus Comittee of Brazilian Society of Rheumatology participate in the development of this guideline. Fourteen PICO questions were defined and a systematic review was performed. Eligible randomized controlled trials were analyzed regarding complete renal remission, partial renal remission, serum creatinine, proteinuria, serum creatinine doubling, progression to end-stage renal disease, renal relapse, and severe adverse events (infections and mortality). The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to develop these recommendations. Recommendations required ≥82% of agreement among the voting members and were classified as strongly in favor, weakly in favor, conditional, weakly against or strongly against a particular intervention. Other aspects of LN management (diagnosis, general principles of treatment, treatment of comorbidities and refractory cases) were evaluated through literature review and expert opinion. Results All SLE patients should undergo creatinine and urinalysis tests to assess renal involvement. Kidney biopsy is considered the gold standard for diagnosing LN but, if it is not available or there is a contraindication to the procedure, therapeutic decisions should be based on clinical and laboratory parameters. Fourteen recommendations were developed. Target Renal response (TRR) was defined as improvement or maintenance of renal function (±10% at baseline of treatment) combined with a decrease in 24-h proteinuria or 24-h UPCR of 25% at 3 months, a decrease of 50% at 6 months, and proteinuria < 0.8 g/24 h at 12 months. Hydroxychloroquine should be prescribed to all SLE patients, except in cases of contraindication. Glucocorticoids should be used at the lowest dose and for the minimal necessary period. In class III or IV (±V), mycophenolate (MMF), cyclophosphamide, MMF plus tacrolimus (TAC), MMF plus belimumab or TAC can be used as induction therapy. For maintenance therapy, MMF or azathioprine (AZA) are the first choice and TAC or cyclosporin or leflunomide can be used in patients who cannot use MMF or AZA. Rituximab can be prescribed in cases of refractory disease. In cases of failure in achieving TRR, it is important to assess adherence, immunosuppressant dosage, adjuvant therapy, comorbidities, and consider biopsy/rebiopsy. Conclusion This consensus provides evidence-based data to guide LN diagnosis and treatment, supporting the development of public and supplementary health policies in Brazil. evidencebased evidence LN. . (LN) 2 guideline performed remission doubling endstage end stage disease relapse infections mortality. mortality mortality) Assessment GRADE (GRADE 82 ≥82 favor conditional intervention diagnosis, (diagnosis opinion involvement but procedure parameters developed TRR (TRR ±10% 10 (±10 24h 24 25 months 50 08 0 8 0. g24 g g/2 1 period ±V, V ±V , (±V) MMF, (MMF) cyclophosphamide TAC, (TAC) therapy AZA (AZA adherence dosage biopsyrebiopsy rebiopsy biopsy/rebiopsy Brazil (LN ≥8 ±10 (±1 5 g2 g/ (±V (MMF (TAC ≥ ±1 (± ± (

https://doi.org/10.1186/s42358-024-00386-8

10.

Benchmarking mobile applications for the health of people with Diabetes Mellitus
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Lopes, Rafael Oliveira Pitta

; Chagas, Sara Rodrigues

; Gomes, Eduardo da Silva

; Barbosa, Joice Cesar de Aguiar

; Silva, Ítalo Rodolfo

; Brandão, Marcos Antônio Gomes

Revista Latino-Americana de Enfermagem

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2024, Volume 32 elocation e4221

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Objetivo: mapear os conteúdos e os recursos dos aplicativos móveis sobre o manejo da Diabetes Mellitus e sua usabilidade nos principais sistemas operacionais. Método: pesquisa de benchmarking . O mapeamento dos apps , dos conteúdos e dos recursos nas plataformas Play Store e App Store foi realizado a partir de uma adaptação na estrutura de revisões de escopo da Joanna Briggs Institute. Para a análise da usabilidade, os aplicativos foram testados por duas semanas e utilizou-se o instrumento System Usability Scale , sendo que escores entre 50-67 pontos, é considerado limítrofe, entre 68-84, produtos com usabilidade aceitável e acima de 85, excelente aceitação pelo usuário e, para a análise, estatística descritiva. Resultados: os conteúdos mais prevalentes foram o manejo da glicemia capilar, alimentação, terapia medicamentosa oral e insulinoterapia. Quanto aos recursos, obteve-se a maior frequência de diários e gráficos. Em relação à usabilidade, dois apps foram considerados de excelente aceitação; 34, produtos com usabilidade aceitável; 29, o recurso pode apresentar algumas falhas, mas tem padrões de usabilidade ainda aceitáveis e 6, com falhas sem condições de usabilidade. Conclusão: os conteúdos e os recursos de aplicativos móveis abordam os pontos fundamentais para o manejo da Diabetes Mellitus com recursos de fácil utilização, com usabilidade aceitável pelos usuários e tem potencial para auxiliar no manejo da Diabetes Mellitus no dia a dia dos pacientes. Objetivo operacionais Método Institute utilizouse utilizou se 5067 50 67 50-6 limítrofe 6884, 6884 68 84, 84 68-84 85 descritiva Resultados capilar alimentação insulinoterapia obtevese obteve gráficos 34 29 6 Conclusão utilização pacientes 506 5 50- 688 8 68-8 3 2 68-

Objective: to map the content and features of mobile applications on the management of Diabetes Mellitus and their usability on the main operating systems. Method: benchmarking research. The mapping of apps, content, and resources on the Play Store and App Store platforms was based on an adaptation of the Joanna Briggs Institute’s scoping review framework. For the usability analysis, the apps were tested for two weeks and the System Usability Scale instrument was used, with scores between 50-67 points being considered borderline, between 68-84, products with acceptable usability and above 85, excellent user acceptance and, for the analysis, descriptive statistics. Results: the most prevalent contents were capillary blood glucose management, diet, oral drug therapy, and insulin therapy. As for resources, diaries and graphs were the most common. With regard to usability, two apps were considered to have excellent usability; 34, products with acceptable usability; 29, the resource may have some flaws but still has acceptable usability standards and 6, with flaws and no usability conditions. Conclusion: the content and resources of mobile applications address the fundamental points for managing Diabetes Mellitus with user-friendly resources, with usability acceptable to users and have the potential to assist in the management of Diabetes Mellitus in patients’ daily lives. Objective systems Method research Institutes Institute s framework analysis used 5067 50 67 50-6 borderline 6884, 6884 68 84, 84 68-84 85 statistics Results diet therapy common 34 29 6 conditions Conclusion userfriendly friendly patients lives 506 5 50- 688 8 68-8 3 2 68-

Objetivo: mapear los contenidos y los recursos de los aplicativos móviles sobre el manejo de la Diabetes Mellitus y su usabilidad en los principales sistemas operacionales. Método: investigaciones de benchmarking . El mapeo de los apps , de los contenidos y recursos en las plataformas Play Store y App Store fue realizado a partir de una adaptación en la estructura de revisiones del objetivo del Joanna Briggs Institute. Para el análisis de la usabilidad, los aplicativos fueron comprobados por dos semanas; para esto, se utilizó el instrumento System Usability Scale , siendo que puntajes entre 50-67 puntos, son considerados limítrofes; entre 68-84, tienen usabilidad aceptable; y, arriba de 85, tienen excelente aceptación por el usuario y para realizar análisis estadística descriptiva. Resultados: los contenidos más prevalentes fueron el manejo de la glucemia capilar, alimentación, terapia medicamentosa oral e insulinoterapia. En cuanto a los recursos se obtuvo mayor frecuencia de diarios y gráficos. En relación a la usabilidad, 2 apps fueron considerados de excelente aceptación; 34, productos con usabilidad aceptable; 29, los apps pueden presentar algunas fallas, sin embargo tiene estándares de usabilidad todavía aceptables; y, 6 presentaron fallas sin condiciones de usabilidad. Conclusión: los contenidos y los recursos de aplicativos móviles abordan los puntos fundamentales para el manejo de la diabetes mellitus, con recursos de fácil utilización, usabilidad aceptable por los usuarios y con potencial para auxiliar en el manejo de la diabetes mellitus, en el día a día de los pacientes. Objetivo operacionales Método Institute semanas esto 5067 50 67 50-6 limítrofes 6884, 6884 68 84, 84 68-84 85 descriptiva Resultados capilar alimentación insulinoterapia gráficos 34 29 aceptables Conclusión mellitus utilización pacientes 506 5 50- 688 8 68-8 3 68-

https://doi.org/10.1590/1518-8345.7182.4221

11.

Patient positioning in minimally invasive gynecologic surgery: strategies to prevent injuries and improve outcomes surgery
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Lopes da Silva Filho, Agnaldo

; Eduardo Soares Pinhati, Matheus

; Lage Neves, Gabriel

; Naves Gonçalves de Almeida, Eduarda

; Lamaita Lopes, Teresa

; Mara Lamaita, Rívia

; Batista Cândido, Eduardo

Revista Brasileira de Ginecologia e Obstetrícia

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2024, Volume 46 elocation e-rbgo46

Abstract: En | Text: En | PDF: En

Abstract Effective patient positioning is a critical factor influencing surgical outcomes, mainly in minimally invasive gynecologic surgery (MIGS) where precise positioning facilitates optimal access to the surgical field. This paper provides a comprehensive exploration of the significance of strategic patient placement in MIGS, emphasizing its role in preventing intraoperative injuries and enhancing overall surgical success. The manuscript addresses potential complications arising from suboptimal positioning and highlights the essential key points for appropriate patient positioning during MIGS, encompassing what the surgical team should or shouldn't do. In this perspective, the risk factors associated with nerve injuries, sliding, compartment syndrome, and pressure ulcers are outlined to guide clinical practice. Overall, this paper underscores the critical role of precise patient positioning in achieving successful MIGS procedures and highlights key principles for the gynecological team to ensure optimal patient outcomes. outcomes (MIGS field success shouldnt shouldn t do perspective sliding syndrome practice Overall

https://doi.org/10.61622/rbgo/2024rbgo46

12.

The impact of a breast cancer diagnosis on marital outcomes and factors associated with divorce and separation
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Werutsky, Gustavo

; Lopes, Mahira

; Jesus, Rafaela Gomes de

; Gazola, Antonia Angeli

; Pellegrini, Rodrigo Azevedo

; Rebelatto, Taiane Francieli

; Freitas, Laura von Wallwitz

; Heck, Ana Paula

; Silva, Arthur Ferreira da

; Rodrigues, Matheus Füehr

; Gössling, Gustavo

; Giacomazzi, Juliana

; Rocha, Matheus Soares

; Rosa, Daniela Dornelles

; Barrios, Carlos Henrique

; Cronemberger, Eduardo Henrique

; Queiroz, Geraldo Silva

; Bines, José

; Simon, Sérgio Daniel

; Fay, Andre Poisl

Revista Brasileira de Ginecologia e Obstetrícia

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2024, Volume 46 elocation e-rbgo60

Abstract: En | Text: En | PDF: En

Abstract Objective To analyze marital outcomes, divorce or separation, and its association with demographic, socioeconomic, and clinicopathological factors among breast cancer (BC) survivors after 2-years of diagnosis. Methods We performed a retrospective analysis of marital status at baseline and at years 1 and 2 of follow-up of women aged ≥ 18 years diagnosed with invasive BC participating in the AMAZONA III (GBECAM0115) study. The BC diagnosis occurred between January 2016 and March 2018 at 23 institutions in Brazil. Results Of the 2974 women enrolled in AMAZONA III, 599 were married or living under common law at baseline. Divorce or separation occurred in 35 (5.8%) patients at 2 years of follow-up. In the multivariate analysis, public health insurance coverage was associated with a higher risk of marital status change (8.25% vs. 2.79%, RR 3.09, 95% CI 1.39 - 7.03, p = 0.007). Women who underwent mastectomy, adenomastectomy or skin-sparing mastectomy were associated with a higher risk of divorce or separation (8.1% vs. 4.49%, RR 1.97, 95 CI 1.04 – 3.72, p = 0.0366) than those who underwent breast-conserving surgery. Conclusion Women covered by the public health system and those who underwent mastectomy, adenomastectomy or skin-sparing mastectomy were associated with a higher risk of divorce or separation. This evidence further supports the idea that long-term marital stability is associated with a complex interplay between socioeconomic conditions and stressors, such as BC diagnosis and treatment. ClinicalTrials Registration: NCT02663973. outcomes demographic (BC 2years followup follow up GBECAM0115 GBECAM (GBECAM0115 study 201 Brazil 297 59 3 5.8% 58 5 8 (5.8% followup. up. 8.25% 825 25 (8.25 vs 279 79 2.79% 309 09 3.09 139 39 1.3 703 7 03 7.03 0.007. 0007 0.007 . 0 007 0.007) skinsparing skin sparing 8.1% 81 (8.1 449 4 49 4.49% 197 97 1.97 9 104 04 1.0 372 72 3.72 0.0366 00366 0366 breastconserving conserving surgery longterm long term stressors treatment Registration NCT02663973 NCT GBECAM011 (GBECAM011 20 29 5.8 (5.8 8.25 82 (8.2 27 2.79 30 3.0 13 1. 70 7.0 000 0.00 00 8.1 (8. 44 4.49 19 1.9 10 37 3.7 0.036 0036 036 NCT0266397 GBECAM01 (GBECAM01 5. (5. 8.2 2.7 3. 7. 0.0 8. (8 4.4 0.03 003 NCT026639 GBECAM0 (GBECAM0 (5 2. 0. ( 4. NCT02663 (GBECAM NCT0266 NCT026 NCT02 NCT0

https://doi.org/10.61622/rbgo/2024rbgo60

13.

Preoperative promestriene for hysteroscopy: a randomized clinical trial hysteroscopy
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Caetano, Isabela Maciel

; Silva Filho, Agnaldo Lopes da

; Lamaita, Rivia Mara

; Maia, Bernardo Avila

; Barroso, Eduardha Santos Temponi

; Candido, Eduardo Batista

Revista da Associação Médica Brasileira

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2024, Volume 70 N. 6 elocation e20231559

Abstract: En | Text: En | PDF: En

SUMMARY OBJECTIVE: Intraoperative complications of hysteroscopy, such as the creation of a false passage, cervix dilatation failure, and uterine perforation, may require suspension of the procedure. Some patients refuse a new procedure, which delays the diagnosis of a possible serious uterine pathology. For this reason, it is essential to develop strategies to increase the success rate of hysteroscopy. Some authors suggest preoperative use of topical estrogen for postmenopausal patients. This strategy is common in clinical practice, but studies demonstrating its effectiveness are scarce. The aim of this study was to evaluate the effect of cervical preparation with promestriene on the incidence of complications in postmenopausal women undergoing surgical hysteroscopy. METHODS: This is a double-blind clinical trial involving 37 postmenopausal patients undergoing surgical hysteroscopy. Participants used promestriene or placebo vaginally daily for 2 weeks and then twice a week for another 2 weeks until surgery. RESULTS: There were 2 out of 14 (14.3%) participants with complications in the promestriene group and 4 out of 23 (17.4%) participants in the placebo group (p=0.593). The complications were difficult cervical dilation, cervical laceration, and vaginal laceration. CONCLUSION: Cervical preparation with promestriene did not reduce intraoperative complications in postmenopausal patients undergoing surgical hysteroscopy. OBJECTIVE hysteroscopy passage failure perforation procedure pathology reason practice scarce METHODS doubleblind double blind 3 surgery RESULTS 1 14.3% 143 (14.3% 17.4% 174 17 (17.4% p=0.593. p0593 p p=0.593 . 0 593 (p=0.593) dilation laceration CONCLUSION 14.3 (14.3 17.4 (17.4 p059 p=0.59 59 (p=0.593 14. (14. 17. (17. p05 p=0.5 5 (p=0.59 (14 (17 p0 p=0. (p=0.5 (1 p=0 (p=0. ( p= (p=0 (p= (p

https://doi.org/10.1590/1806-9282.20231559

14.

Diretriz de Tomografia Computadorizada e Ressonância Magnética Cardiovascular da Sociedade Brasileira de Cardiologia e do Colégio Brasileiro de Radiologia – 2024 202 20 2
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Magalhães, Tiago Augusto

; Carneiro, Adriano Camargo de Castro

; Moreira, Valéria de Melo

; Trad, Henrique Simão

; Lopes, Marly Maria Uellendahl

; Cerci, Rodrigo Julio

; Nacif, Marcelo Souto

; Schvartzman, Paulo R.

; Chagas, Antônio Carlos Palandrini

; Costa, Isabela Bispo Santos da Silva

; Schmidt, André

; Shiozaki, Afonso Akio

; Montenegro, Sérgio Tavares

; Piegas, Leopoldo Soares

; Zapparoli, Marcelo

; Nicolau, José Carlos

; Fernandes, Fabio

; Hadlich, Marcelo Souza

; Ghorayeb, Nabil

; Mesquita, Evandro Tinoco

; Gonçalves, Luiz Flávio Galvão

; Ramires, Felix José Alvarez

; Fernandes, Juliano de Lara

; Schwartzmann, Pedro Vellosa

; Rassi, Salvador

; Torreão, Jorge Andion

; Mateos, José Carlos Pachón

; Beck-da-Silva, Luiz

; Silva, Marly Conceição

; Liberato, Gabriela

; Oliveira, Gláucia Maria Moraes de

; Feitosa Filho, Gilson Soares

; Carvalho, Hilka dos Santos Moraes de

; Markman Filho, Brivaldo

; Rocha, Ricardo Paulo de Sousa

; Azevedo Filho, Clerio Francisco de

; Taratsoutchi, Flávio

; Coelho-Filho, Otavio Rizzi

; Kalil Filho, Roberto

; Hajjar, Ludhmila Abrahão

; Ishikawa, Walther Yoshiharu

; Melo, Cíntia Acosta

; Jatene, Ieda Biscegli

; Albuquerque, Andrei Skromov de

; Rimkus, Carolina de Medeiros

; Silva, Paulo Savoia Dias da

; Vieira, Thiago Dieb Ristum

; Jatene, Fabio Biscegli

; Azevedo, Guilherme Sant Anna Antunes de

; Santos, Raul D.

; Monte, Guilherme Urpia

; Ramires, José Antonio Franchini

; Bittencourt, Marcio Sommer

; Avezum, Alvaro

; Silva, Leonardo Sara da

; Abizaid, Alexandre

; Gottlieb, Ilan

; Precoma, Dalton Bertolim

; Szarf, Gilberto

; Sousa, Antônio Carlos Sobral

; Pinto, Ibraim Masciarelli Francisco

; Medeiros, Fábio de Morais

; Caramelli, Bruno

; Parga Filho, José Rodrigues

; Santos, Tiago Senra Garcia dos

; Prazeres, Carlos Eduardo Elias dos

; Lopes, Marcelo Antonio Cartaxo Queiroga

; Avila, Luiz Francisco Rodrigues de

; Scanavacca, Mauricio Ibrahim

; Gowdak, Luis Henrique Wolff

; Barberato, Silvio Henrique

; Nomura, Cesar Higa

; Rochitte, Carlos Eduardo

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 9 elocation e20240608

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.36660/abc.20240608

15.

Spotted fever diagnosis using molecular methods
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Marques, Helen Gonçalves

; Ribeiro, Anna Julia

; Gadelha, Anna Karolina de Oliveira Alfenas

; Resende, Carlos Ananias Aparecido

; Silva, Daniela Regiane da

; Deus, Débora Patrícia Martins de

; Barcelos, Isabelle Caroline Dos Santos

; Pereira, Isabela Maia

; Paula, Iago Tadeu Santos de

; Lopes, Lucas Da Silva

; Silva, Líria Souza

; Lopes, Mariana Campos da Paz

; Chávez-Fumagalli, Miguel Angel

; Coelho, Eduardo Antônio Ferraz

; Giunchetti, Rodolfo Cordeiro

; Gonçalves, Ana Alice Maia

; Galdino, Alexsandro Sobreira

Revista da Sociedade Brasileira de Medicina Tropical

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2024, Volume 57 elocation e00204-2024

Abstract: En | Text: En | PDF: En

ABSTRACT Rickettsiosis is a disease caused by bacteria belonging to the genus Rickettsia, and is a potentially fatal zoonotic disease of great medical and veterinary importance. Given the urgent need to develop new diagnostic methods for detecting this disease, the present review aimed to evaluate the number of publications dedicated to the identification of Rickettsia spp. in human samples using molecular methods, such as polymerase chain reaction and its variations. To this end, a bibliographical survey covering articles published in the past ten years was conducted using the PudMed platform with the keywords “spotted fever” and “Rickettsia,” both combined with “diagnosis.” A growing number of publications in this area reflects an increasing interest in research, especially since 2015. From 2015 to February 2024, several promising results were tested and many studies were able to detect the genetic sequences of interest. Therefore, the absence of a standard diagnosis method highlights the critical need for developing an effective technique capable of accurately detecting the etiological agent and ensuring accurate diagnosis of the disease. importance spp variations end spotted fever “Rickettsia, diagnosis. “diagnosis. research 201 2024 Therefore “Rickettsia “diagnosis 20 202 2

https://doi.org/10.1590/0037-8682-0226-2024

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