Abstract Objective: To estimate the prevalence of excessive weight and to identify associations with socioeconomic, demographic, biological, and lifestyle factors in adolescents. Methods: It is a cross-sectional school-based study, with a stratified and complex sample. The evaluated individuals were adolescents (2404), aged 12-17 years old, participating in the Study of Cardiovascular Risk Factors in Adolescents (ERICA). Demographic, socioeconomic, biological, anthropometric, and lifestyle variables were assessed. Poisson regression was used to verify the association between excess weight and independent variables. Results: The prevalence of excessive weight was 26.3% in the study population, being 16.3% for overweight and 10% for obesity. In the multivariate analysis (hierarchical model), were associated with excessive weight: private education network, a higher number of televisions in the residence, eating habits related to the breakfast consumption, snacks purchase in the canteen, snacks in front to screens consumption and consumption of carbohydrates and lipids, in addition to age group (12-14 years) and sexual maturation (post-pubertal). Conclusions: The prevalence of excessive weight among the school adolescents studied is high, with a value higher than the national average and the results of previous studies with adolescents. Its distribution is associated with different factors, which are socioeconomic, demographic, biological, and related to lifestyle, reinforcing the complexity of this condition, which deserves a broad coping approach, involving not only individual efforts but social and public ones as well.

OBJECTIVE: Considering the rapid spread of COVID-19, the scientific community has been looking for ways to recognize factors that may interfere with the outcome of viral infection. Despite the lack of studies with the new coronavirus, it is known that adequate serum levels of micronutrients are essential for the organic response to infectious diseases. Thus, we aim to review the effects of vitamin A, D, iron, zinc, or folate deficiency on the prognosis of patients with respiratory infections with manifestations similar to COVID-19 and discuss about supplementation of the nutrients analyzed in this review. METHODS: The search was conducted in the databases PubMed, Lilacs, and SciELO, including observational studies published between 2010-2020, with results for individuals with respiratory tract infections with manifestations similar to COVID-19. RESULTS: Six articles met the inclusion criteria, all of which were related to deficiencies of vitamins A and D. In general, vitamin A deficiency was associated with cough, fever, and greater total respiratory resistance. Regarding vitamin D, the lack of this nutrient led to higher rates of ICU admission, the need for mechanical ventilation, and mortality. Evidence linking specific relationships between nutritional deficiencies and COVID-19 remain lacking due to the small number of studies and heterogeneities in population subgroups. CONCLUSION: In conclusion, deficiencies of vitamins A and D seem to negatively affect the prognosis of respiratory tract infections. Supplementation of these nutrients for prevention or treatment of patients diagnosed with COVID-19 should respect serum levels, nutritional status and housing conditions (e.g.,endemic location) of individuals.

RESUMO Objetivo: Identificar a prevalência de resistência à insulina em adolescentes e verificar sua associação com variáveis metabólicas e com o consumo alimentar. Métodos: Estudo transversal, de base escolar, com amostra do tipo estratificada e complexa. Os indivíduos analisados foram adolescentes (n=1.081) participantes do Estudo de Riscos Cardiovasculares em Adolescentes (ERICA) na cidade de Recife (Pernambuco, Brasil). Foram coletadas variáveis demográficas, socioeconômicas, comportamentais, antropométricas, bioquímicas e do consumo alimentar. A resistência à insulina foi definida como HOMA-IR>percentil 75. Análises de regressão de Poisson com ajuste robusto da variância foram empregadas, sendo identificadas associações estatisticamente significativas quando p≤0,05. Resultados: A idade mediana foi de 14 anos (intervalo interquartílico=13-16) e a resistência à insulina foi evidenciada em 25,3% da amostra. As variáveis que se associaram significativamente com a resistência à insulina no modelo final foram a faixa etária, o índice de massa corpórea por idade (IMC/I), marcadores bioquímicos (triglicerídeos e HDL-colesterol) e o consumo alimentar de gordura saturada, observando-se maior prevalência da resistência à insulina naqueles indivíduos que apresentaram a ingestão deste tipo de gordura abaixo da mediana da própria distribuição. Conclusões: A resistência à insulina foi prevalente nos adolescentes avaliados e se associou significativamente com variáveis metabólicas e com o consumo alimentar de gordura do tipo saturada.

ABSTRACT Objective: To identify the prevalence of insulin resistance in adolescents and its associations with metabolic factors and food intake. Methods: Cross-sectional study conducted with a stratified, complex, school-based sample. The subjects were adolescents (n=1,081) who participated in the Study of Cardiovascular Risk in Adolescents in the city of Recife (Pernambuco, Brazil). We analyzed demographic, socioeconomic, behavioral, anthropometric, biochemical, and dietary variables. Insulin resistance was defined as HOMA-IR>75th percentile. A Poisson multivariate regression model with robust variance adjustment was used, and variables with p≤0.05 in the final model were considered statistically associated with insulin resistance. Results: Median age was 14 years (interquartile range: 13-16 years), and 25.3% of the sample showed insulin resistance. The variables associated with insulin resistance in the final model were age, body mass index-for-age (BMI/A), biochemical markers (triglycerides and high-density lipoprotein cholesterol) and saturated fat intake, with insulin resistance being more prevalent in individuals whose consumption of this type of fat was below the median of the sample distribution. Conclusions: Insulin resistance was prevalent in the adolescents analyzed and was significantly associated with metabolic variables and saturated fat intake.

Resumo O objetivo do presente estudo é verificar a associação entre o excesso de peso em adolescentes e o estado nutricional dos pais e identificar possíveis fatores determinantes. A pesquisa foi realizada nas bases de dados Pubmed, Lilacs, Scielo e Biblioteca Virtual de Saúde (BVS), considerando-se o período de 2004 a 2014. Os descritores usados foram: “Adolescente”, “Fatores de risco”, “Obesidade”, “Pais” e “Sobrepeso”. Dos 366 artigos encontrados, apenas 07 atenderam a todos os critérios de elegibilidade. Notou-se nos adolescentes prevalência de sobrepeso mais elevada nos estudos realizados no Brasile na Grécia, enquanto a prevalência de obesidade foi maior nos estudos conduzidos nos Estados Unidos. Foram verificadas maiores prevalências de excesso de peso em adolescentes do sexo masculino. Todos os trabalhos mostraram que a presença de sobrepeso ou obesidade no pai ou na mãe aumenta o risco dos adolescentes desenvolverem excesso de peso, e esse risco é ainda maior quando ambos os pais são obesos. A grande associação entre excesso de peso nos adolescentes e estado nutricional dos pais está relacionada com inúmeros fatores, dessa forma, a presença de um fator de risco, como, por exemplo, a predisposição genética, pode ser amenizada por um fator de proteção, como hábitos alimentares saudáveis.

Abstract The article seeks to investigate the association between overweight in adolescents and the nutritional state of the parents and identify possible determinants. The search was carried out in the Pubmed, Lilacs, Scielo databases and Virtual Health Library (BVS), were searched regarding the period from 2004 to 2014. The descriptors were: “Adolescent”, “Risk factors”, “Obesity”, “Parents” and “Overweight”. Of the 366 articles, only 07 met al.l the eligibility criteria. Higher prevalence of overweight in adolescents was noted in studies conducted in Brazil and Greece, while the prevalence of obesity was higher in studies conducted in United States. Higher overweight prevalence in male adolescents was verified. All studies showed that the presence of overweight or obesity in the father or the mother increases the risk of adolescents developing overweight, and this risk is even greater when both parents are obese. The strong association between overweight in adolescents and nutritional status of the parents found in the selected studies is related to many factors, thus the presence of a risk factor, such as genetic predisposition, can be ameliorated by a protective factor, such as healthy eating habits.

Resumo O objetivo do presente estudo é verificar a associação entre o excesso de peso em adolescentes e o estado nutricional dos pais e identificar possíveis fatores determinantes. A pesquisa foi realizada nas bases de dados Pubmed, Lilacs, Scielo e Biblioteca Virtual de Saúde (BVS), considerando-se o período de 2004 a 2014. Os descritores usados foram: “Adolescente”, “Fatores de risco”, “Obesidade”, “Pais” e “Sobrepeso”. Dos 366 artigos encontrados, apenas 07 atenderam a todos os critérios de elegibilidade. Notou-se nos adolescentes prevalência de sobrepeso mais elevada nos estudos realizados no Brasile na Grécia, enquanto a prevalência de obesidade foi maior nos estudos conduzidos nos Estados Unidos. Foram verificadas maiores prevalências de excesso de peso em adolescentes do sexo masculino. Todos os trabalhos mostraram que a presença de sobrepeso ou obesidade no pai ou na mãe aumenta o risco dos adolescentes desenvolverem excesso de peso, e esse risco é ainda maior quando ambos os pais são obesos. A grande associação entre excesso de peso nos adolescentes e estado nutricional dos pais está relacionada com inúmeros fatores, dessa forma, a presença de um fator de risco, como, por exemplo, a predisposição genética, pode ser amenizada por um fator de proteção, como hábitos alimentares saudáveis.

Abstract The article seeks to investigate the association between overweight in adolescents and the nutritional state of the parents and identify possible determinants. The search was carried out in the Pubmed, Lilacs, Scielo databases and Virtual Health Library (BVS), were searched regarding the period from 2004 to 2014. The descriptors were: “Adolescent”, “Risk factors”, “Obesity”, “Parents” and “Overweight”. Of the 366 articles, only 07 met al.l the eligibility criteria. Higher prevalence of overweight in adolescents was noted in studies conducted in Brazil and Greece, while the prevalence of obesity was higher in studies conducted in United States. Higher overweight prevalence in male adolescents was verified. All studies showed that the presence of overweight or obesity in the father or the mother increases the risk of adolescents developing overweight, and this risk is even greater when both parents are obese. The strong association between overweight in adolescents and nutritional status of the parents found in the selected studies is related to many factors, thus the presence of a risk factor, such as genetic predisposition, can be ameliorated by a protective factor, such as healthy eating habits.

Resumo Objetivo: Identificar os pontos de corte do índice Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) estabelecidos para adolescentes e discutir a sua aplicabilidade para o diagnóstico da resistência à insulina em adolescentes brasileiros. Fontes de dados: Revisão sistemática feita nas bases de dados PubMed, Lilacs e SciELO com os descritores "Adolescentes", "Resistência à insulina" e "Curva ROC". Foram incluídos artigos originais, publicados entre 2005 e 2015, conduzidos com adolescentes, no idioma português, inglês ou espanhol e incluindo análise estatística com uso da curva ROC para determinação dos pontos de corte do índice (HOMA-IR). Síntese dos dados: Foram identificados 184 artigos e, após a aplicação das etapas do procedimento, foram selecionados sete para compor a revisão. Todos os estudos selecionados estabeleceram seus pontos de corte com a curva ROC. O menor ponto de corte observado foi de 1,65 para meninas e 1,95 para meninos e o maior de 3,82 para meninas e 5,22 para meninos. Dos estudos analisados, um propôs validade externa, recomendando o uso do ponto de corte do HOMA-IR >2,5 para ambos os sexos. Conclusões: O índice HOMA-IR constitui-se em método confiável para deteção da resistência insulínica em adolescentes, desde que usados os pontos de corte que mais se adequem à realidade da população em estudo, o que permite um diagnóstico precoce da resistência à insulina e possibilita intervenções multiprofissionais para a promoção da saúde dessa população.

Abstract Objective: To identify cutoff points of the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) index established for adolescents and discuss their applicability for the diagnosis of insulin resistance in Brazilian adolescents. Data source: A systematic review was performed in the PubMed, Lilacs and SciELO databases, using the following descriptors: "adolescents", "insulin resistance" and "Receiver Operating Characteristics Curve". Original articles carried out with adolescents published between 2005 and 2015 in Portuguese, English or Spanish languages, which included the statistical analysis using Receiver Operating Characteristics Curve to determine the index cutoff (HOMA-IR) were included. Data synthesis: A total of 184 articles were identified and after the study phases were applied, seven articles were selected for the review. All selected studies established their cutoffs using a Receiver Operating Characteristics Curve, with the lowest observed cutoff of 1.65 for girls and 1.95 for boys and the highest of 3.82 for girls and 5.22 for boys. Of the studies analyzed, one proposed external validity, recommending the use of the HOMA-IR cutoff>2.5 for both genders. Conclusions: The HOMA-IR index constitutes a reliable method for the detection of insulin resistance in adolescents, as long as it uses cutoffs that are more adequate for the reality of the study population, allowing early diagnosis of insulin resistance and enabling multidisciplinary interventions aiming at health promotion of this population.