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RESUMO Objetivo: Descrever o IMPACTO-MR, um estudo brasileiro de plataforma nacional em unidades de terapia intensiva focado no impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Métodos: Descrevemos a plataforma IMPACTO-MR, seu desenvolvimento, critérios para seleção das unidades de terapia intensiva, caracterização da coleta de dados, objetivos e projetos de pesquisa futuros a serem realizados na plataforma. Resultados: Os dados principais foram coletados por meio do Epimed Monitor System® e consistiram em dados demográficos, dados de comorbidades, estado funcional, escores clínicos, diagnóstico de internação e diagnósticos secundários, dados laboratoriais, clínicos e microbiológicos e suporte de órgãos durante a internação na unidade de terapia intensiva, entre outros. De outubro de 2019 a dezembro de 2020, 33.983 pacientes de 51 unidades de terapia intensiva foram incluídos no banco de dados principal. Conclusão: A plataforma IMPACTO-MR é um banco de dados clínico brasileiro de unidades de terapia intensiva focado na pesquisa do impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Essa plataforma fornece dados para o desenvolvimento e pesquisa de unidades de terapia intensiva individuais e ensaios clínicos observacionais e prospectivos multicêntricos. Objetivo IMPACTOMR, IMPACTOMR IMPACTO MR, MR saúde Métodos Resultados System demográficos comorbidades funcional secundários laboratoriais outros 201 2020 33983 33 983 33.98 5 principal Conclusão multicêntricos 20 202 3398 3 98 33.9 2 339 9 33.

ABSTRACT Objective: To describe the IMPACTO-MR, a Brazilian nationwide intensive care unit platform study focused on the impact of health care-associated infections due to multidrug-resistant bacteria. Methods: We described the IMPACTO-MR platform, its development, criteria for intensive care unit selection, characterization of core data collection, objectives, and future research projects to be held within the platform. Results: The core data were collected using the Epimed Monitor System® and consisted of demographic data, comorbidity data, functional status, clinical scores, admission diagnosis and secondary diagnoses, laboratory, clinical, and microbiological data, and organ support during intensive care unit stay, among others. From October 2019 to December 2020, 33,983 patients from 51 intensive care units were included in the core database. Conclusion: The IMPACTO-MR platform is a nationwide Brazilian intensive care unit clinical database focused on researching the impact of health care-associated infections due to multidrug-resistant bacteria. This platform provides data for individual intensive care unit development and research and multicenter observational and prospective trials. Objective IMPACTOMR, IMPACTOMR IMPACTO MR, MR careassociated associated multidrugresistant multidrug resistant bacteria Methods selection collection objectives Results System status scores diagnoses laboratory stay others 201 2020 33983 33 983 33,98 5 Conclusion trials 20 202 3398 3 98 33,9 2 339 9 33,

https://doi.org/10.5935/0103-507x.20220209-pt

[SciELO Preprints] - Guideline of the Brazilian Society of Cardiology on Diagnosis and Treatment of Patients with Chagas Disease Cardiomyopathy
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Marin-Neto, José Antonio Rassi Jr., Anis Moraes Oliveira, Gláucia M. Lemos Correia, Luís Claudio Novaes Ramos Jr., Alberto Hasslocher-Moreno, Alejandro Marcel Luquetti Ostermayer, Alejandro Sousa, Andréa Silvestre de Amato Vincenzo de Paola, Angelo Sobral de Sousa, Antonio Carlos Pinho Ribeiro, Antonio Luiz Correia Filho, Dalmo Moraes de Souza, Dilma do Socorro Cunha-Neto, Edecio J. A. Ramires, Felix Bacal, Fernando Pereira Nunes, Maria do Carmo Martinelli Filho, Martino Ibrahim Scanavacca, Maurício Magalhães Saraiva, Roberto Alves de Oliveira Júnior, Wilson M. Lorga-Filho, Adalberto de Jesus Benevides de Almeida Guimarães, Adriana Lopes Latado Braga, Adriana Sarmento de Oliveira, Adriana V. L. Sarabanda, Alvaro Yecê das Neves Pinto, Ana Assis Lopes do Carmo, André Schmidt, André Costa, Andréa Rodrigues da Ianni, Barbara Maria Markman Filho, Brivaldo Eduardo Rochitte, Carlos Thé Macedo, Carolina Mady, Charles Chevillard, Christophe Bittencourt das Virgens, Cláudio Marcelo Nery de Castro, Cleudson De Paoli de Carvalho Britto, Constança Felícia Pisani, Cristiano do Carmo Rassi, Daniela C. Sobral Filho, Dario Rodrigues Almeida, Dirceu A. Bocchi, Edimar T. Mesquita, Evandro de Souza Nogueira Sardinha Mendes, Fernanda Pereira, Francisca Tatiana Sperandio da Silva, Gilberto Marcelo de Lima Peixoto, Giselle Glotz de Lima, Gustavo H. Veloso, Henrique Turin Moreira, Henrique Bellotti Lopes, Hugo Masciarelli Francisco Pinto, Ibraim Pinto Dias, João Carlos Bemfica, João Marcos Silva-Nunes, João Paulo Soares Barreto-Filho, José Augusto Kerr Saraiva, José Francisco Lannes-Vieira, Joseli Menezes Oliveira, Joselina Luzia V. Armaganijan, Luciana Martins, Luiz Cláudio C. Sangenis, Luiz Henrique Barbosa, Marco Paulo Almeida-Santos, Marcos Antônio Simões, Marcos Vinicius Shikanai-Yasuda, Maria Aparecida Vieira Moreira, Maria da Consolação Higuchi, Maria de Lourdes Costa Monteiro, Maria Rita de Cássia Felix Mediano, Mauro Felippe Maia Lima, Mayara T. Oliveira, Maykon Moreira Dias Romano , Minna Nitz, Nadjar de Tarso Jorge Medeiros, Paulo Vieira Alves, Renato Alkmim Teixeira, Ricardo Coury Pedrosa, Roberto Aras, Roque Morais Torres, Rosália dos Santos Povoa, Rui Manoel Rassi, Sérgio Gabriel Salles Xavier, Sérgio Marinho Martins Alves , Silvia B. N. Tavares, Suelene Lima Palmeira, Swamy da Silva Junior, Telêmaco Luiz da Rocha Rodrigues, Thiago Madrini Junior, Vagner Maia da Costa , Veruska Dutra, Walderez

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Publication date: 2022-10-11

Abstract: En Pt

This guideline aimed to update the concepts and formulate the standards of conduct and scientific evidence that support them, regarding the diagnosis and treatment of the Cardiomyopathy of Chagas disease, with special emphasis on the rationality base that supported it.nbsp; Chagas disease in the 21st century maintains an epidemiological pattern of endemicity in 21 Latin American countries. Researchers and managers from endemic and non-endemic countries point to the need to adopt comprehensive public health policies to effectively control the interhuman transmission of T. cruzi infection, and to obtain an optimized level of care for already infected individuals, focusing on diagnostic and therapeutic opportunistic opportunities. nbsp; Pathogenic and pathophysiological mechanisms of the Cardiomyopathy of Chagas disease were revisited after in-depth updating and the notion that necrosis and fibrosis are stimulated by tissue parasitic persistence and adverse immune reaction, as fundamental mechanisms, assisted by autonomic and microvascular disorders, was well established. Some of them have recently formed potential targets of therapies.nbsp; The natural history of the acute and chronic phases was reviewed, with enhancement for oral transmission, indeterminate form and chronic syndromes. Recent meta-analyses of observational studies have estimated the risk of evolution from acute and indeterminate forms and mortality after chronic cardiomyopathy. Therapeutic approaches applicable to individuals with Indeterminate form of Chagas disease were specifically addressed. All methods to detect structural and/or functional alterations with various cardiac imaging techniques were also reviewed, with recommendations for use in various clinical scenarios. Mortality risk stratification based on the Rassi score, with recent studies of its application, was complemented by methods that detect myocardial fibrosis.nbsp; The current methodology for etiological diagnosis and the consequent implications of trypanonomic treatment deserved a comprehensive and in-depth approach. Also the treatment of patients at risk or with heart failure, arrhythmias and thromboembolic events, based on pharmacological and complementary resources, received special attention. Additional chapters supported the conducts applicable to several special contexts, including t. cruzi/HIV co-infection, risk during surgeries, in pregnant women, in the reactivation of infection after heart transplantation, and others.nbsp; nbsp;nbsp; Finally, two chapters of great social significance, addressing the structuring of specialized services to care for individuals with the Cardiomyopathy of Chagas disease, and reviewing the concepts of severe heart disease and its medical-labor implications completed this guideline.

Esta diretriz teve como objetivo principal atualizar os conceitos e formular as normas de conduta e evidências científicas que as suportam, quanto ao diagnóstico e tratamento da CDC, com especial ênfase na base de racionalidade que a embasou. A DC no século XXI mantém padrão epidemiológico de endemicidade em 21 países da América Latina. Investigadores e gestores de países endêmicos e não endêmicos indigitam a necessidade de se adotarem políticas abrangentes, de saúde pública, para controle eficaz da transmissão inter-humanos da infecção pelo T. cruzi, e obter-se nível otimizado de atendimento aos indivíduos já infectados, com foco em oportunização diagnóstica e terapêutica. Mecanismos patogênicos e fisiopatológicos da CDC foram revisitados após atualização aprofundada e ficou bem consolidada a noção de que necrose e fibrose sejam estimuladas pela persistência parasitária tissular e reação imune adversa, como mecanismos fundamentais, coadjuvados por distúrbios autonômicos e microvasculares. Alguns deles recentemente constituíram alvos potenciais de terapêuticas. A história natural das fases aguda e crônica foi revista, com realce para a transmissão oral, a forma indeterminada e as síndromes crônicas. Metanálises recentes de estudos observacionais estimaram o risco de evolução a partir das formas aguda e indeterminada e de mortalidade após instalação da cardiomiopatia crônica. Condutas terapêuticas aplicáveis aos indivíduos com a FIDC foram abordadas especificamente. Todos os métodos para detectar alterações estruturais e/ou funcionais com variadas técnicas de imageamento cardíaco também foram revisados, com recomendações de uso nos vários cenários clínicos. Estratificação de risco de mortalidade fundamentada no escore de Rassi, com estudos recentes de sua aplicação, foi complementada por métodos que detectam fibrose miocárdica. A metodologia atual para diagnóstico etiológico e as consequentes implicações do tratamento tripanossomicida mereceram enfoque abrangente e aprofundado. Também o tratamento de pacientes em risco ou com insuficiência cardíaca, arritmias e eventos tromboembólicos, baseado em recursos farmacológicos e complementares, recebeu especial atenção. Capítulos suplementares subsidiaram as condutas aplicáveis a diversos contextos especiais, entre eles o da co-infecção por T. cruzi/HIV, risco durante cirurgias, em grávidas, na reativação da infecção após transplante cardíacos, e outros.nbsp;nbsp;nbsp; Por fim, dois capítulos de grande significado social, abordando a estruturação de serviços especializados para atendimento aos indivíduos com a CDC, e revisando os conceitos de cardiopatia grave e suas implicações médico-trabalhistas completaram esta diretriz.nbsp;

https://doi.org/10.1590/SciELOPreprints.4820

Establishment of tropical forage grasses in the Cerrado biome
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Gurgel, Antonio Leandro Chaves

; Difante, Gelson dos Santos

; Costa, Carolina Marques

; Emerenciano Neto, João Virgínio

; Tonhão, Gustavo Henrique

; Ítavo, Luís Carlos Vinhas

; Dias, Alexandre Menezes

; Vilela, Iuri Mesquita Moraes

; Oliveira, Vivian Garcia de

; Lima, Pâmella Cristina da Silva

; Miyake, Andrey William Alce

Revista mexicana de ciencias pecuarias

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sep 2022, Volume 13 N. 3 Pages 674 - 689

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract This study was carried out to evaluate the time for the establishment of tropical forage grasses in the “Cerrado” biome, based on morphogenetic and structural traits. Three Brachiaria brizantha (Syn. Urochloa brizantha) cultivars (Paiaguás, Ipyporã and Marandu) and two Panicum maximum (Syn. Megathyrsus maximus) cultivars (Quênia and Tamani) were distributed in a randomized-block design with four replicates. Morphogenetic and structural traits of the pasture were assessed from d 35 to d 65 after sowing, at seven-day interval. Canopy height rose linearly with the establishment period, in all cultivars. In the Megathyrsus cultivars, tiller density decreased as the experimental period progressed, whereas the number of tillers in the Urochloa cultivars increased. The cultivars Ipyporã and Marandu had the highest leaf appearance rates. The lowest leaf elongation rates occurred in the cultivars Paiaguás, Ipyporã and Tamani, and the highest elongation rates in cv. Quênia. As a result, cv. Quênia showed the highest values of final leaf length (64.9 cm) and leaf blade mass (3,352.9 kg DM ha-1). The higher senescence rate of cv. Tamani (2.1 cm tiller-1 d-1) resulted in the highest percentage of dead material (1,815.5 kg ha-1) being found in the herbage mass of this cultivar. Cultivars Paiaguás, Marandu and Tamani were established at 44 d, whereas cv. Quênia and Ipyporã were established at 51 and 58 d after sowing, respectively, in the Brazilian Cerrado.

Resumen Este estudio se llevó a cabo para evaluar el tiempo para el establecimiento de gramíneas forrajeras tropicales en el bioma del “Cerrado”, con base en rasgos morfogenéticos y estructurales. Se distribuyeron tres cultivares (Paiaguás, Ipyporã y Marandu) de Brachiaria brizantha (Sin. Urochloa brizantha) y dos cultivares (Quênia y Tamani) de Panicum maximum (Sin. Megathyrsus maximus) en un diseño de bloques al azar con cuatro repeticiones. Los rasgos morfogenéticos y estructurales del pasto se evaluaron desde el día 35 hasta el día 65 después de la siembra, a intervalos de siete días. La altura del dosel aumentó linealmente con el período de establecimiento, en todos los cultivares. En los cultivares de Megathyrsus, la densidad de macollos disminuyó a medida que avanzaba el período experimental, mientras que el número de macollos en los cultivares de Urochloa aumentó. Los cultivares Ipyporã y Marandu tuvieron las tasas más altas de aparición foliar. Las tasas de elongación foliar más bajas se presentaron en los cultivares Paiaguás, Ipyporã y Tamani, y las tasas de elongación más altas en el cv. Quênia. Como resultado, el cv. Quênia mostró los valores más altos de longitud foliar final (64.9 cm) y masa de lámina foliar (3,352.9 kg MS ha-1). La mayor tasa de senescencia del cv. Tamani (2.1 cm macollo-1 d-1) dio como resultado que el mayor porcentaje de material muerto (1,815.5 kg ha-1) se encontrara en la masa de forraje de este cultivar. Los cultivares Paiaguás, Marandu y Tamani se establecieron a los 44 d, mientras que los cv. Quênia e Ipyporã se establecieron a los 51 y 58 días después de la siembra, respectivamente, en el Cerrado brasileño.

https://doi.org/10.22319/rmcp.v13i3.6039 17 downloads

Effect of supplementation of ewes in the final third of gestation on the development of their lambs
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Campos, Nathália Rafaela Fidelis

; Difante, Gelson dos Santos

; Gurgel, Antonio Leandro Chaves

; Costa, Carolina Marques

; Montagner, Denise Baptaglin

; Emerenciano Neto, João Virgínio

; Ítavo, Luís Carlos Vinhas

; Ítavo, Camila Celeste Brandão Ferreira

; Carvalho Netto, Roldão Teixeira de

; Véras, Emmanuel Lievio de Lima

; Costa, Ana Beatriz Graciano da

Revista Brasileira de Zootecnia

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2022, Volume 51 elocation e20210094

Abstract: En | Text: En | PDF: En

ABSTRACT This study examined the effect of different supplementation strategies for ewes in the last third of gestation, kept on a deferred Brachiaria brizantha cv. Marandu pasture, on their performance and the growth curve of their lambs. A total of 54 ewes, of no defined breed, with an average weight of 41.10±3.10 kg, were used in a completely randomized design, divided into three groups (18 ewes per treatment). In total, 61 lambs were born, 28 females and 33 males, with 3.70±0.55 and 3.68±0.69 kg birth weight, respectively. Treatments were as follows: multiple mixture ad libitum, concentrate supplement at 0.4% live weight (LW), and concentrate supplement at 0.8% LW. Average daily weight gain (ADG, g/animal/day) and total weight gain (TWG, kg/animal) were evaluated in ewes and lambs. Reproductive efficiency indices were measured in the ewes and biometric variables in the lambs. The ADG and TWG of ewes in the last third of gestation were higher in animals supplemented at 0.8% LW. Reproductive efficiency results were superior in ewes supplemented at 0.4% LW. The effect of ewe supplementation on lamb growth curve as estimated by the Gompertz model did not reveal differences between the curves of lambs born to ewes that received supplementation at 0.4 and 0.8% LW. However, supplementing ewes with a multiple mixture induced a reduction in the growth curve parameters of their lambs. The use of concentrated supplementation, at levels of 0.4 and 0.8% of LW, provides greater productive and reproductive performance for ewes and lambs.

https://doi.org/10.37496/rbz5120210094

Neurological, cognitive and learning evaluation of students who were born preterm
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Carmo, André Luis Santos do

; Fredo, Fernanda Wagner

; Bruck, Isac

; Lima, Joseli do Rocio Maito de

; Janke, Rebecca Nóbrega Ribas Gusso Harder

; Fogaça, Thais da Glória Messias

; Glaser, Jacqueline Andrea

; Riechi, Tatiana Izabele Jaworski de Sá

; Antoniuk, Sergio Antonio

Revista Paulista de Pediatria

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2022, Volume 40 elocation e2020252

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Avaliar o perfil de desenvolvimento cognitivo e acadêmico de recém-nascidos pré-termo em idade escolar e indicar os fatores relacionados à prematuridade e ao perfil sociodemográfico que influenciam esse resultado. Métodos: Recrutaram-se pacientes com idades entre 6 e 14 anos que fizeram seguimento no ambulatório de acompanhamento de prematuros. As capacidades cognitiva, acadêmica e neurológica foram acessadas por avaliação pormenorizada com neuropediatra, neuropsicóloga e psicopedagoga. Buscaram-se os dados neonatais nos prontuários. Resultados: Foram incluídos 97 recém-nascidos pré-termo e excluídos 14, resultando em 83 crianças. A idade gestacional foi 30±3 semanas e o peso de nascimento 1138g (605; 4185g). Tiveram mau desempenho em escrita 38,4%, leitura 57,5% e matemática 42,5%. A média de quociente de inteligência total foi de 96,0±14,9 pontos, sendo 10,9% considerados alterados. Crianças com famílias desestruturadas apresentaram 78,3% de falha de leitura (p=0,029). Pela regressão multivariada, houve relação entre idade gestacional ao nascimento e pontuação no miniexame do estado mental (minimental) clássico (p=0,043), quociente de inteligência total (p=0,047), quociente de inteligência organização perceptual (p=0,035) e quociente de inteligência velocidade de processamento (p=0,036); entre peso ao nascer e minimental clássico (p=0,004) e adaptado (p=0,007); entre tempo de ventilação mecânica invasiva e minimental clássico (p=0,049); e entre idade materna mais baixa e quociente de inteligência velocidade de processamento (p=0,033). Conclusões: Os recém-nascidos pré-termo apresentaram alta frequência de falha nos testes de avaliação cognitiva e acadêmica. Uma série de intercorrências neonatais apresenta associação com alterações no desenvolvimento cognitivo e escolar.

ABSTRACT Objective: To evaluate the cognitive and academic profile of preterm newborns at school age and to determine the factors related to prematurity and sociodemographic profile that influence these results. Methods: Patients aged 6-14 years old that were assisted in the preterm follow-up clinic were recruited. The cognitive, academic, and neurological capacities were accessed through a detailed evaluation with a child neurologist, a neuropsychologist and a psychopedagogue. Neonatal data were collected from patient records. Results: 97 children were included and 14 were excluded from the study, resulting in 83 children. Gestational age (GA) was 30±3 weeks and weight at birth was 1138g (605 to 4185g). Poor performance was shown in 38.4% for writing, 57.5% for reading and 42.5% for mathematics. The mean total intelligence quotient (IQ) was 96±14.9 points, and 10.9% were considered altered. Children with unstructured families presented 78.3% of failure in reading tests (p=0.029). The multivariate analysis showed association between GA at birth and classic mini-mental score (p=0.043), total IQ (p=0.047), perceptual organization IQ (p=0.035), and processing speed IQ (p=0.036). There was also association between weight at birth and the classic (p=0.004) and adapted (p=0.007) mini-mental scores; invasive mechanic ventilation duration and classic mini-mental (p=0.049); and lower maternal age and processing speed IQ (p=0.033). Conclusions: Preterm infants at school age had high frequency of failure in cognitive and academic evaluation tests. Learning difficulties are high among them. Multiple neonatal variables are related with altered cognitive and students development.

https://doi.org/10.1590/1984-0462/2022/40/2020252 3 downloads

Sources of polyunsaturated fatty acids from oilseeds in dairy cows diets can alter yield of and fatty acid profile in milk
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WANDERLEY, Alysson Martins

; ÍTAVO, Luís Carlos Vinhas

; SANTOS, Geraldo Tadeu dos

; ÍTAVO, Camila Celeste Brandão Ferreira

; DIAS, Alexandre Menezes

; DIFANTE, Gelson dos Santos

; GURGEL, Antonio Leandro Chaves

; CUNHA, Camila Soares

; MATEUS, Rodrigo Gonçalves

; CARDOSO, Claudia Andréa Lima

; OLIVEIRA, Marcus Vinícius Moraes de

Food Science and Technology

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2022, Volume 42 elocation e119021

Abstract: En | Text: En | PDF: En

Abstract Our hypothesis was that different sources of unsaturated fatty acids from oilseeds (sunflower, soybeans, and cottonseed) could alter milk yield, fatty acid profile, and the amount of unsaturated fatty acids yielded in milk. It aimed to evaluate the effects of lipid sources on yield and composition and fatty acids in milk of primiparous Girolando cows. Five cows in lactation (35 ± 8 days), with 410 ± 7.15 kg BW were randomly distributed in a 5 x 5 Latin square. Five experimental diets, namely a control diet without an additional source of lipid and four diets with different lipid sources: cottonseed, sunflower seed, whole soybean, or soybean oil, as lipid source, to reach 70 g/kg of ethereal extract dry matter basis were used. Cottonseed and soybean oil addition reduced daily yield by 15 and 22%. Oilseed can alter fatty acid profile in milk. Whole soybean provided greater daily milk and fatty acids yields.

https://doi.org/10.1590/fst.119021

10.

Diretrizes Brasileiras de Hipertensão Arterial – 2020
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Barroso, Weimar Kunz Sebba

; Rodrigues, Cibele Isaac Saad

; Bortolotto, Luiz Aparecido

; Mota-Gomes, Marco Antônio

; Brandão, Andréa Araujo

; Feitosa, Audes Diógenes de Magalhães

; Machado, Carlos Alberto

; Poli-de-Figueiredo, Carlos Eduardo

; Amodeo, Celso

; Mion Júnior, Décio

; Barbosa, Eduardo Costa Duarte

; Nobre, Fernando

; Guimarães, Isabel Cristina Britto

; Vilela-Martin, José Fernando

; Yugar-Toledo, Juan Carlos

; Magalhães, Maria Eliane Campos

; Neves, Mário Fritsch Toros

; Jardim, Paulo César Brandão Veiga

; Miranda, Roberto Dischinger

; Póvoa, Rui Manuel dos Santos

; Fuchs, Sandra C

; Alessi, Alexandre

; Lucena, Alexandre Jorge Gomes de

; Avezum, Alvaro

; Sousa, Ana Luiza Lima

; Pio-Abreu, Andrea

; Sposito, Andrei Carvalho

; Pierin, Angela Maria Geraldo

; Paiva, Annelise Machado Gomes de

; Spinelli, Antonio Carlos de Souza

; Nogueira, Armando da Rocha

; Dinamarco, Nelson

; Eibel, Bruna

; Forjaz, Cláudia Lúcia de Moraes

; Zanini, Claudia Regina de Oliveira

; Souza, Cristiane Bueno de

; Souza, Dilma do Socorro Moraes de

; Nilson, Eduardo Augusto Fernandes

; Costa, Elisa Franco de Assis

; Freitas, Elizabete Viana de

; Duarte, Elizabeth da Rosa

; Muxfeldt, Elizabeth Silaid

; Lima Júnior, Emilton

; Campana, Erika Maria Gonçalves

; Cesarino, Evandro José

; Marques, Fabiana

; Argenta, Fábio

; Consolim-Colombo, Fernanda Marciano

; Baptista, Fernanda Spadotto

; Almeida, Fernando Antonio de

; Borelli, Flávio Antonio de Oliveira

; Fuchs, Flávio Danni

; Plavnik, Frida Liane

; Salles, Gil Fernando

; Feitosa, Gilson Soares

; Silva, Giovanio Vieira da

; Guerra, Grazia Maria

; Moreno Júnior, Heitor

; Finimundi, Helius Carlos

; Back, Isabela de Carlos

; Oliveira Filho, João Bosco de

; Gemelli, João Roberto

; Mill, José Geraldo

; Ribeiro, José Marcio

; Lotaif, Leda A. Daud

; Costa, Lilian Soares da

; Magalhães, Lucélia Batista Neves Cunha

; Drager, Luciano Ferreira

; Martin, Luis Cuadrado

; Scala, Luiz César Nazário

; Almeida, Madson Q.

; Gowdak, Marcia Maria Godoy

; Klein, Marcia Regina Simas Torres

; Malachias, Marcus Vinícius Bolívar

; Kuschnir, Maria Cristina Caetano

; Pinheiro, Maria Eliete

; Borba, Mario Henrique Elesbão de

; Moreira Filho, Osni

; Passarelli Júnior, Oswaldo

; Coelho, Otavio Rizzi

; Vitorino, Priscila Valverde de Oliveira

; Ribeiro Junior, Renault Mattos

; Esporcatte, Roberto

; Franco, Roberto

; Pedrosa, Rodrigo

; Mulinari, Rogerio Andrade

; Paula, Rogério Baumgratz de

; Okawa, Rogério Toshiro Passos

; Rosa, Ronaldo Fernandes

; Amaral, Sandra Lia do

; Ferreira-Filho, Sebastião R.

; Kaiser, Sergio Emanuel

; Jardim, Thiago de Souza Veiga

; Guimarães, Vanildo

; Koch, Vera H.

; Oigman, Wille

; Nadruz, Wilson

Arquivos Brasileiros de Cardiologia

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mar 2021, Volume 116 N. 3 Pages 516 - 658

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20201238 10948 downloads

11.

Selection of carioca common bean lines with slow darkening
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Pereira, Helton Santos

; Mendonça, Fabiana Rocha

; Rodrigues, Ludivina Lima

; Melo, Leonardo Cunha

; Melo, Patrícia Guimarães Santos

; Faria, Luís Cláudio de

; Costa, Antônio Félix da

; Carvalho, Hélio Wilson Lemos de

; Pereira Filho, Israel Alexandre

; Almeida, Válter Martins de

Pesquisa Agropecuária Brasileira

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2021, Volume 56 elocation e02471

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste trabalho foi avaliar a interação entre genótipos e ambientes para o escurecimento de grãos de feijão carioca (Phaseolus vulgaris), a fim de selecionar linhagens que associem escurecimento lento, arquitetura ereta, tolerância ao acamamento, e maior produtividade e peso de 100 grãos, com boa adaptabilidade e estabilidade para esses caracteres. Foram avaliadas 44 linhagens pré-selecionadas, oriundas de cruzamentos entre uma cultivar com escurecimento lento e arquitetura prostrada e quatro cultivares com escurecimento normal e arquitetura ereta, em experimentos de campo conduzidos em 15 ambientes (combinações de locais, épocas de semeadura e anos). Ao se considerar as médias, a adaptabilidade e a estabilidade para cada caráter isoladamente, a maior parte das linhagens apresentou desempenho satisfatório: 75% para escurecimento lento, 48% para alta produtividade, 59% para arquitetura ereta, 84% para tolerância ao acamamento e 68% para peso de 100 grãos. Os efeitos dos ambientes e da interação entre genótipos e ambientes são importantes para os cinco caracteres estudados. As linhagens CNFC 16754 e CNFC 16820 apresentam escurecimento lento dos grãos, alta produtividade e peso de 100 grãos, plantas mais eretas e alta tolerância ao acamamento, além de alta adaptabilidade e estabilidade para esses caracteres, o que mostra o seu potencial para recomendação como novas cultivares e confirma que é possível reunir fenótipos desejáveis para os cinco caracteres avaliados.

Abstract The objective of this work was to evaluate the interaction between genotypes and environment for seed-coat darkening of common bean (Phaseolus vulgaris) seeds, in order to select lines that combine slow darkening, upright plants, resistance to lodging, and higher yield and 100-grain weight, with good adaptability and stability for these traits. Forty four pre-selected lines, originating from crosses between one cultivar with slow darkening and prostrate plants and four cultivars with normal darkening and upright plants, were evaluated in field trials conducted in 15 environments (combinations of locations, crop seasons, and years). Considering the mean values, adaptability, and stability for each isolated trait, most of the lines presented satisfactory performance: 75% for slow darkening, 48% for high yield, 59% for upright plants, 84% for resistance to lodging, and 68% for 100-grain weight. The effects of environments and of the genotype by environment interaction are important for the five studied traits. The CNFC 16754 and CNFC 16820 lines present slow seed-coat darkening, high yield and 100-grain weight, more upright plant architecture, and greater resistance to lodging, besides high adaptability and stability for these traits, which shows their potential for recommendation as new cultivars and confirms that it is possible to join desirable phenotypes for the five traits evaluated.

https://doi.org/10.1590/s1678-3921.pab2021.v56.02471

12.

Unsatisfactory microbiological aspects of UHT goat milk, soymilk and dairy beverage of goat milk and soy protein: A public health issue
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ANJOS, Taís Ramalho dos

; CAVICCHIOLI, Valéria Quintana

; LIMA, Joyce Aparecida Santos

; VASCONCELLOS, Alenia Naliato

; VAZ, Andréia Cristina Nakashima

; ROSSI, Gabriel Augusto Marques

; CAMPOS-GALVÃO, Maria Emilene Martino

; TODOROV, Svetoslav Dimitrov

; MATHIAS, Luis Antonio

; SCHOCKEN-ITURRINO, Rubén Pablo

; NERO, Luís Augusto

; VIDAL, Ana Maria Centola

Food Science and Technology

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jun 2020, Volume 40 Pages 349 - 354

Abstract: En | Text: En | PDF: En

Abstract Spore forming bacteria can play an important role in food quality and safety as spoilage and pathogenic microorganisms due to resistance to heat-treatment. However, there are limited number of studies focused on evaluate the microbiological quality and the occurrence of these bacteria in UHT goat milk, soymilk and dairy beverage of goat milk and soy protein. In this context, 75 samples of these beverages were evaluated regarding heterotrophic mesophilic microorganisms by conventional plate count and selective methods to detect microorganisms from Bacillus cereus group and Clostridium perfringens. Population counts greater than 104 CFU.ml-1 of heterotrophic mesophilic microorganisms were observed in 80% of the lots of goat milk and 100% of the lots of soymilk and dairy beverage of goat milk and soy protein. The presence of bacteria belonging to B. cereus group was observed in 16%, 52% and 44% of goat milk, soymilk and dairy beverage of goat milk and soy protein, respectively. C. perfringens was isolated from 8% samples of UHT soymilk. The frequency of genes hblA, hblB, hblC, nheA, nheB, nheC in 29 isolates obtained from these products was 62%, 48.2%, 96.5%, 79.3%, 68.9% and 79.3%, respectively. The microbiological quality of the evaluated products was unsatisfactory.

https://doi.org/10.1590/fst.14019 677 downloads

13.

Epidemiologia e desfecho dos pacientes de alto risco cirúrgico admitidos em unidades de terapia intensiva no Brasil
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Silva Júnior, João Manoel

; Chaves, Renato Carneiro de Freitas

; Corrêa, Thiago Domingos

; Assunção, Murillo Santucci Cesar de

; Katayama, Henrique Tadashi

; Bosso, Fabio Eduardo

; Amendola, Cristina Prata

; Serpa Neto, Ary

; Malbouisson, Luiz Marcelo Sá

; Oliveira, Neymar Elias de

; Veiga, Viviane Cordeiro

; Rojas, Salomón Soriano Ordinola

; Postalli, Natalia Fioravante

; Alvarisa, Thais Kawagoe

; Lucena, Bruno Melo Nobrega de

; Oliveira, Raphael Augusto Gomes de

; Sanches, Luciana Coelho

; Silva, Ulysses Vasconcellos de Andrade e

; Nassar Junior, Antonio Paulo

; Réa-Neto, Álvaro

; Amaral, Alexandre

; Teles, José Mário

; Freitas, Flávio Geraldo Rezende de

; Bafi, Antônio Tonete

; Pacheco, Eduardo Souza

; Ramos, Fernando José

; Vieira Júnior, José Mauro

; Pereira, Maria Augusta Santos Rahe

; Schwerz, Fábio Sartori

; Menezes, Giovanna Padoa de

; Magalhães, Danielle Dourado

; Castro, Cristine Pilati Pileggi

; Henrich, Sabrina Frighetto

; Toledo, Diogo Oliveira

; Parra, Bruna Fernanda Camargo Silva

; Dias, Fernando Suparregui

; Zerman, Luiza

; Formolo, Fernanda

; Nobrega, Marciano de Sousa

; Piras, Claudio

; Piras, Stéphanie de Barros

; Conti, Rodrigo

; Bittencourt, Paulo Lisboa

; D’Oliveira, Ricardo Azevedo Cruz

; Estrela, André Ricardo de Oliveira

; Oliveira, Mirella Cristine de

; Reese, Fernanda Baeumle

; Motta Júnior, Jarbas da Silva

; Câmara, Bruna Martins Dzivielevski da

; David-João, Paula Geraldes

; Tannous, Luana Alves

; Chaiben, Viviane Bernardes de Oliveira

; Miranda, Lorena Macedo Araújo

; Brasil, José Arthur dos Santos

; Deucher, Rafael Alexandre de Oliveira

; Ferreira, Marcos Henrique Borges

; Vilela, Denner Luiz

; Almeida, Guilherme Cincinato de

; Nedel, Wagner Luis

; Passos, Matheus Golenia dos

; Marin, Luiz Gustavo

; Oliveira Filho, Wilson de

; Coutinho, Raoni Machado

; Oliveira, Michele Cristina Lima de

; Friedman, Gilberto

; Meregalli, André

; Höher, Jorge Amilton

; Soares, Afonso José Celente

; Lobo, Suzana Margareth Ajeje

Revista Brasileira de Terapia Intensiva

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mar 2020, Volume 32 N. 1 Pages 17 - 27

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Definir o perfil epidemiológico e os principais determinantes de morbimortalidade dos pacientes cirúrgicos não cardíacos de alto risco no Brasil. Métodos: Estudo prospectivo, observacional e multicêntrico. Todos os pacientes cirúrgicos não cardíacos admitidos nas unidades de terapia intensiva, ou seja, considerados de alto risco, no período de 1 mês, foram avaliados e acompanhados diariamente por, no máximo, 7 dias na unidade de terapia intensiva, para determinação de complicações. As taxas de mortalidade em 28 dias de pós-operatório, na unidade de terapia intensiva e hospitalar foram avaliadas. Resultados: Participaram 29 unidades de terapia intensiva onde foram realizadas cirurgias em 25.500 pacientes, dos quais 904 (3,5%) de alto risco (intervalo de confiança de 95% - IC95% 3,3% - 3,8%), tendo sido incluídos no estudo. Dos pacientes envolvidos, 48,3% eram de unidades de terapia intensiva privadas e 51,7% de públicas. O tempo de internação na unidade de terapia intensiva foi de 2,0 (1,0 - 4,0) dias e hospitalar de 9,5 (5,4 - 18,6) dias. As taxas de complicações foram 29,9% (IC95% 26,4 - 33,7) e mortalidade em 28 dias pós-cirurgia 9,6% (IC95% 7,4 - 12,1). Os fatores independentes de risco para complicações foram Simplified Acute Physiology Score 3 (SAPS 3; razão de chance − RC = 1,02; IC95% 1,01 - 1,03) e Sequential Organ Failure Assessment Score (SOFA) da admissão na unidade de terapia intensiva (RC =1,17; IC95% 1,09 - 1,25), tempo de cirurgia (RC = 1,001; IC95% 1,000 - 1,002) e cirurgias de emergências (RC = 1,93; IC95% 1,10 - 3,38). Em adição, foram associados com mortalidade em 28 dias idade (RC = 1,032; IC95% 1,011 - 1,052) SAPS 3 (RC = 1,041; IC95% 1,107 - 1,279), SOFA (RC = 1,175; IC95% 1,069 - 1,292) e cirurgias emergenciais (RC = 2,509; IC95% 1,040 - 6,051). Conclusão: Pacientes com escores prognósticos mais elevados, idosos, tempo cirúrgico e cirurgias emergenciais estiveram fortemente associados a maior mortalidade em 28 dias e mais complicações durante permanência em unidade de terapia intensiva.

ABSTRACT Objective: To define the epidemiological profile and the main determinants of morbidity and mortality in noncardiac high surgical risk patients in Brazil. Methods: This was a prospective, observational and multicenter study. All noncardiac surgical patients admitted to intensive care units, i.e., those considered high risk, within a 1-month period were evaluated and monitored daily for a maximum of 7 days in the intensive care unit to determine complications. The 28-day postoperative, intensive care unit and hospital mortality rates were evaluated. Results: Twenty-nine intensive care units participated in the study. Surgeries were performed in 25,500 patients, of whom 904 (3.5%) were high-risk (95% confidence interval - 95%CI 3.3% - 3.8%) and were included in the study. Of the participating patients, 48.3% were from private intensive care units, and 51.7% were from public intensive care units. The length of stay in the intensive care unit was 2.0 (1.0 - 4.0) days, and the length of hospital stay was 9.5 (5.4 - 18.6) days. The complication rate was 29.9% (95%CI 26.4 - 33.7), and the 28-day postoperative mortality rate was 9.6% (95%CI 7.4 - 12.1). The independent risk factors for complications were the Simplified Acute Physiology Score 3 (SAPS 3; odds ratio - OR = 1.02; 95%CI 1.01 - 1.03) and Sequential Organ Failure Assessment Score (SOFA) on admission to the intensive care unit (OR = 1.17; 95%CI 1.09 - 1.25), surgical time (OR = 1.001, 95%CI 1.000 - 1.002) and emergency surgeries (OR = 1.93, 95%CI, 1.10 - 3.38). In addition, there were associations with 28-day mortality (OR = 1.032; 95%CI 1.011 - 1.052), SAPS 3 (OR = 1.041; 95%CI 1.107 - 1.279), SOFA (OR = 1.175, 95%CI 1.069 - 1.292) and emergency surgeries (OR = 2.509; 95%CI 1.040 - 6.051). Conclusion: Higher prognostic scores, elderly patients, longer surgical times and emergency surgeries were strongly associated with higher 28-day mortality and more complications during the intensive care unit stay.

https://doi.org/10.5935/0103-507x.20200005 1048 downloads

14.

Occurrence of Phelypera griseofasciata and its parasitism in munguba in Seropédica, Rio de Janeiro
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Souza, Thiago Sampaio de

; Aguiar-Menezes, Elen de Lima

; Resende, André Luis Santos

; Costa, Valmir Antonio

; Trevisan, Henrique

Arquivos do Instituto Biológico

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2020, Volume 87 elocation e1122018

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: Pachira aquatica (Malvaceae), conhecida como munguba, é cultivada para arborização de muitas cidades brasileiras. No campus de Seropédica da UFRRJ, observou-se o desfolhamento de um espécime de Pachira aquatica, com a presença de larvas, pré-pupas e pupas de besouro da subfamília Hyperinae, que foram criadas em laboratório até a emergência dos adultos; esses insetos foram identificados como pertencentes à espécie Phelypera griseofasciata Capiomont (Coleoptera: Curculionidae). Essas formas imaturas (n=86) foram novamente coletadas nesse mesmo espécime e criadas em laboratório para verificar a ocorrência de parasitismo. Foram obtidos 128 adultos de Jaliscoa nudipennis Bouček (Hymenoptera: Pteromalidae), responsáveis por 44,2% do parasitismo total. A razão sexual foi de 0,70, portanto, o maior número de descendentes foi de fêmeas. Observaram-se ainda os dimorfismos inter e intrasexuais em J. nudipennis quanto ao formato da cabeça e às características das asas. Este estudo trata-se do primeiro registro de ambas as espécies de insetos associadas a Pachira aquatica no estado do Rio de Janeiro, Brasil.

ABSTRACT: Pachira aquatica (Malvaceae), known as munguba, is cultivated for afforestation of many Brazilian cities. In Seropédica campus of UFRRJ, it was observed the defoliation of one specimen of Pachira aquatica with presence of larvae, pre-pupae, and pupae of beetle of the subfamily Hyperinae, which were reared in laboratory until the emergence of the adults; these insects were identified as belonging to the species Phelypera griseofasciata Capiomont (Coleoptera: Curculionidae). These immature forms (n=86) were again collected in this same specimen and reared in laboratory to verify the occurrence of parasitism. It was obtained 128 adults of Jaliscoa nudipennis Bouček (Hymenoptera: Pteromalidae), responsible for 44.2% of total parasitism. The sex ratio was 0.70, so the highest number of offspring was of females. Intersexual and intrasexual dimorphisms were also observed in J. nudipennis regarding the shape of the head and characteristics of the wings. This study is the first record of both insect species associated with Pachira aquatica in the state of Rio de Janeiro, Brazil.

https://doi.org/10.1590/1808-1657001122018 808 downloads

15.

Chemical composition and antinociceptive activity of volatile fractions of the aerial parts of Solidago chilensis (Compositae)
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Valverde, Simone Sacramento

; Souza, Stefânia Priscilla de

; Oliveira, Temistocles Barroso de

; Kelly, Andressa Maia

; Costa, Nathalia Ferreira

; Calheiros, Andrea Surrage

; Lima, Keila dos Santos Cople

; Frutuoso, Valber da Silva

; Lima, Antônio Luís dos Santos

Rodriguésia

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2020, Volume 71 elocation e00862019

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Trinta e seis compostos foram identificados à partir de partes aéreas de Solidago chilensis cultivadas na PAF/FIOCRUZ, na cidade do Rio de Janeiro, usando microextração em fase sólida (MEFS) e analisados por cromatografia gasosa-espectrometria de massa (CG-EM). Estes compostos são principalmente mono terpenos não oxigenados e sesquiterpenos. O Germacreno D é o composto majoritário de duas amostras de óleo essencial analisadas (12 a 23%) e de duas amostras voláteis analisadas por MEFS. Limoneno é o composto majoritário da amostra de inflorescências frescas (cerca de 21%). O acetato de bornila está presente em ambas as frações, voláteis (16%) e óleos essenciais (7-8%). Todas as amostras de óleos essenciais avaliadas apresentaram boa atividade antinociceptiva, considerando a dose utilizada das amostras (1 mg/kg) e a substância padrão (50 mg/kg). Solidago chilensis é uma das arnicas brasileiras e é uma planta medicinal amplamente utilizada pela população brasileira. Outras plantas do gênero Solidago também são utilizadas na medicina tradicional na América do Norte e na Europa. Este é o primeiro relato da análise de MEFS do gênero Soligado e do efeito antinociceptivo do óleo essencial de Solidago chilensis.

Abstract Thirty-six compounds were identified from aerial parts of Solidago chilensis cultivated at PAF/FIOCRUZ campus in Rio de Janeiro city (RJ) using solid-phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS) analysis. These compounds are mainly non-oxygenated mono and sesquiterpenes. Germacrene D is the major compound of two the essential oil analyzed samples (12 to 23%) and of two of the volatiles samples analyzed by SPME (central stems and dry inflorescences samples). Limonene is the major compound in the fresh inflorescences sample (about 21%). The bornil acetate is present in both volatile fractions (16%) and essential oils (7-8%). All the essential oils samples evaluated shown a great antinociceptive activity, considering the used dose of the samples (1 mg/kg) and the standard substance (50 mg/kg). Solidago chilensis is one of Brazil arnicas and it is a medicinal plant widely used by the brazilian population. Other plants of the genus Solidago are also used in traditional medicine in North America and Europe. This is the first report of SPME analysis from Solidago genus and of the antinociceptive effect from Solidago chilensis essential oil.

https://doi.org/10.1590/2175-7860202071053 261 downloads

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