RESUMO: O objetivo deste trabalho foi extrair lignina de Eucalyptus sp. licor negro kraft e avaliar a influência de sua adição nas propriedades do adesivo lignina-fenol-formaldeído. Os adesivos foram sintetizados em diferentes porcentagens de massa de fenol por lignina, denominados adesivos lignina-fenol-formaldeído nas proporções de 25, 30, 50, 75 e 80%. Os parâmetros avaliados nos adesivos foram pH, teor de sólidos totais, teor de compostos orgânicos, teor de compostos inorgânicos, tempo de gelatinização e comportamento do adesivo na linha de cola. O pH variou de 10,63 a 11,65. Para o teor de sólidos totais foi encontrado o valor de 53 a 69%. Os teores de compostos orgânicos variaram de 51 a 75% e de inorgânicos de 25 a 49%. Observou-se que com a adição da macromolécula na formulação do adesivo, o teor de sólidos totais e orgânicos foi reduzido proporcionalmente enquanto o de sólidos inorgânicos foi elevado. O tempo de gelatinização foi reduzido devido à adição de lignina. As menores proporções de adição apresentaram melhor penetração e fluidez na interface com a madeira. A lignina kraft extraída do licor negro kraft de eucalipto é um ótimo adesivo com potencial para substituir parcialmente o fenol derivado do petróleo, com grande potencial para uso e aplicação nos setores aeronáutico e automotivo, no processo de colagem de peças estruturais. RESUMO sp ligninafenolformaldeído. ligninafenolformaldeído formaldeído. formaldeído 30 50 7 80 80% cola 1063 10 63 10,6 1165 11 65 11,65 5 69 69% 2 49 49% Observouse Observou se elevado madeira petróleo automotivo estruturais 3 8 106 1 6 10, 116 11,6 4 11,

ABSTRACT: The objective of this research was to extract lignin from Eucalyptus sp. kraft black liquor and to evaluate the influence of its addition on the properties of the lignin-phenol-formaldehyde adhesive. The adhesives were synthesized at different phenol mass percentages by lignin, called lignin-phenol-formaldehyde adhesives in the proportions of 25, 30, 50, 75 and 80%. The parameters evaluated in the adhesives were pH, total solid content, organic compound content, inorganic compound content, gelatinization time and adhesive behavior in the glue line. The pH ranged from 10.63 to 11.65. For the total solid content was found the value of 53 to 69 %. The contents of organic compounds ranged from 51 to 75% and inorganic from 25 to 49%. It was observed that with the addition of macromolecule in the adhesive formulation, the total and organic solid content was reduced proportionally while the inorganic solid was high. The gelatinization time was reduced due to the addition of lignin. The lower proportions of addition presented better penetration and fluidity in interface with the wood. The kraft lignin extracted from eucalyptus kraft black liquor is a great adhesive with potential to partially replace petroleum-derived phenol, with great potential for use and application in the aeronautical and automotive sectors, in the bonding process of structural parts. ABSTRACT sp ligninphenolformaldehyde formaldehyde 30 50 7 80 80% line 1063 10 63 10.6 1165 11 65 11.65 5 6 % 2 49 49% formulation high wood petroleumderived petroleum derived sectors parts 3 8 106 1 10. 116 11.6 4 11.

RESUMO: No estado do Amazonas cultiva-se, tradicionalmente, a laranjeira ‘Pêra’ sobre o limoeiro ‘Cravo’. O uso restrito de uma única combinação de copa-porta-enxerto tem deixado os pomares locais vulneráveis à condições adversas e a incidência de pragas e doenças, podendo interferir negativamente tanto na produtividade como na qualidade dos frutos e sustentabilidade citrícola do Estado. A ampliação do número de combinações-copas-porta-enxertos torna-se uma alternativa viável para superar tais problemas. Para atender a esta demanda dos produtores de citros foram avaliadas 30 combinações com 10 copas e três porta-enxertos no sexto e sétimo ano após o plantio das mudas no campo, no município de Rio Preto da Eva, AM. Nesse experimento foram avaliadas: a produtividade, o rendimento de suco, os sólidos solúveis, o pH, a acidez titulável, o ratio e o índice tecnológico. A copa ‘Pineapple’ com os porta-enxertos tangerineira ‘Sunki Tropical’ e ‘BRS Bravo’ podem ser alternativas produtivas em relação a tradicional combinação laranja ‘Pêra’ sob limoeiro ‘Cravo’ no Amazonas. A copa laranja ‘Lima’ com os porta-enxertos tangerineira ‘Sunki Tropical’, limoeiro ‘Cravo Santa Cruz’ e ‘BRS Bravo’ podem ser alternativas para o mercado in natura no estado. As combinações que apresentaram boa qualidade do fruto são as copas ‘Pêra’, ‘Salustiana’, ‘Valência Tuxpan’ e ‘Westin’ com o porta-enxerto ‘BRS Bravo’, e a copa ‘Pêra D6’ com o porta-enxerto limoeiro ‘Cravo Santa Cruz’. Estas combinações são alternativas para a diversificação dos pomares do estado do Amazonas. RESUMO cultivase, cultivase cultiva se, se cultiva-se tradicionalmente Pêra ‘Cravo. Cravo . copaportaenxerto porta enxerto doenças Estado combinaçõescopasportaenxertos enxertos tornase torna problemas 3 1 portaenxertos campo Eva AM suco solúveis pH titulável tecnológico ‘Pineapple Pineapple Sunki Tropical BRS Bravo ‘Lima Lima Tropical, , Cruz ‘Pêra, ‘Salustiana, Salustiana ‘Salustiana ‘Salustiana’ Valência Tuxpan ‘Westin Westin portaenxerto Bravo, D6 D Cruz.

ABSTRACT: In the state of Amazonas, the ‘Pêra’ orange scion is traditionally cultivated on ‘Rangpur’ lime tree. The restricted use of a single scion-rootstock combination has left local orchards vulnerable to adverse conditions and incidence of pests and diseases, which may negatively interfere with both productivity and fruit quality and the citrus activity sustainability in the state. The expansion of the number of scion-rootstock combinations becomes a viable alternative to overcome such problems. To meet this demand from citrus growers, 30 combinations with 10 scions and 3 rootstocks were evaluated in the sixth and seventh year after planting seedlings in the field in the municipality of Rio Preto da Eva, AM. In this experiment, productivity, juice yield, soluble solids, pH, titratable acidity, ratio and technological index were evaluated. ‘Pineapple’ scion with ‘Sunki Tropical’ and ‘BRS Bravo’ rootstocks can be productive alternatives in relation to traditional ‘Pêra’ orange scion under ‘Rangpur’ lime combination in the state of Amazonas. ‘Lima’ orange with ‘Sunki Tropical’ mandarin, ‘Rangpur lime SC’ and ‘BRS Bravo’ lime rootstocks can be alternatives for the fresh market in the state. Combinations that showed good fruit quality are ‘Pêra’, ‘Salustiana’, ‘Valência Tuxpan’ and ‘Westin’ scions with ‘BRS Bravo’ rootstock, and ‘Pêra D6’ scion with ‘Rangpur lime SC’ lemon rootstock. These combinations are alternatives for the diversification of orchards in the state of Amazonas. ABSTRACT Amazonas Pêra Rangpur tree scionrootstock rootstock diseases problems growers 1 Eva AM experiment yield solids pH acidity ‘Pineapple Pineapple Sunki Tropical BRS Bravo ‘Lima Lima mandarin SC ‘Pêra, , ‘Salustiana, Salustiana ‘Salustiana ‘Salustiana’ Valência Tuxpan ‘Westin Westin D6 D

ABSTRACT BACKGROUND: Emotional distress increases, also affected by the setting. OBJECTIVE: To estimate changes in prevalence of severe anxiety and depressive symptoms and associated factors. DESIGN AND SETTING: This cross-sectional study included adults living in Manaus selected through a three-stage probability sampling in 2015 and 2019. METHODS: This is an analysis of two surveys conducted. The outcomes were assessed by Generalized Anxiety Disorder 7-item (≥ 15 points) and Patient Health Questionnaire 9-item (≥ 20), and changes were tested by chi-square goodness-of-fit. Prevalence ratios (PR) with 95% confidence intervals (95%CI) were calculated by Poisson regression. RESULTS: Severe anxiety symptoms increased from 3.3% (95%CI = 2.7–3.9) in 2015 (n = 3,479) to 8.7% (95%CI = 7.5–9.8) in 2019 (n = 2,321); severe depressive symptoms changed from 2.5% (95%CI = 2.0–3.0) to 8.5% (95%CI = 7.3–9.6). Variations were more pronounced in social vulnerability (P < 0.05). Outcomes were higher in women (anxiety: PR = 1.27; 95%CI = 1.20–1.34, depression: PR = 1.35; 95%CI = 1.27–1.44), low-income individuals (anxiety: PR = 1.90; 95%CI = 1.20–3.00, depression: PR = 1.98; 95%CI = 1.22–3.19), less educated individuals (anxiety: PR = 2.20; 95%CI = 1.16–4.18, depression: PR = 2.37; 95%CI = 1.23–4.60), and individuals with poor health status (anxiety: PR = 9.06; 95%CI = 6.72–12.21, depression: PR = 8.99; 95%CI = 6.67–12.12). CONCLUSION: Severe anxiety and depression tripled in Manaus, potentially reflecting Brazilian socioeconomic crises. BACKGROUND increases setting OBJECTIVE factors SETTING crosssectional cross sectional threestage three stage 201 METHODS conducted 7item item 7 ≥ ( 1 points 9item 9 20, 20 , 20) chisquare chi square goodnessoffit. goodnessoffit goodness fit. fit goodness-of-fit (PR 95 95CI CI regression RESULTS 33 3 3.3 2.7–3.9 2739 2 n 3,479 3479 479 87 8 8.7 7.5–9.8 7598 5 2,321 2321 321 2,321) 25 2.5 2.0–3.0 2030 0 85 8.5 7.3–9.6. 7396 7.3–9.6 . 6 7.3–9.6) P 0.05. 005 0.05 05 0.05) (anxiety 1.27 127 27 120134 34 1.20–1.34 1.35 135 35 1.27–1.44, 127144 1.27–1.44 44 1.27–1.44) lowincome low income 1.90 190 90 120300 00 1.20–3.00 1.98 198 98 1.22–3.19, 122319 1.22–3.19 22 19 1.22–3.19) 2.20 220 116418 16 4 18 1.16–4.18 2.37 237 37 1.23–4.60, 123460 1.23–4.60 23 60 1.23–4.60) 9.06 906 06 6721221 72 12 21 6.72–12.21 8.99 899 99 6.67–12.12. 6671212 6.67–12.12 67 6.67–12.12) CONCLUSION crises 3. 2.7–3. 273 3,47 347 47 8. 7.5–9. 759 2,32 232 32 2. 2.0–3. 203 739 7.3–9. 0.0 1.2 12013 1.20–1.3 1.3 13 12714 1.27–1.4 1.9 12030 1.20–3.0 12231 1.22–3.1 2.2 11641 1.16–4.1 2.3 12346 1.23–4.6 9.0 672122 6.72–12.2 8.9 89 667121 6.67–12.1 2.7–3 3,4 7.5–9 75 2,3 2.0–3 73 7.3–9 0. 1. 1201 1.20–1. 1271 1.27–1. 1203 1.20–3. 1223 1.22–3. 1164 1.16–4. 1234 1.23–4. 9. 67212 6.72–12. 66712 6.67–12. 2.7– 3, 7.5– 2, 2.0– 7.3– 120 1.20–1 1.27–1 1.20–3 122 1.22–3 116 1.16–4 123 1.23–4 6721 6.72–12 6671 6.67–12 2.7 7.5 2.0 7.3 1.20– 1.27– 1.22– 11 1.16– 1.23– 672 6.72–1 667 6.67–1 7. 1.20 1.22 1.16 1.23 6.72– 66 6.67– 1.1 6.72 6.67 6.7 6.6 6.

Resumen: Introducción: Las ostomías de eliminación se definen como una externalización de parte del sistema digestivo por efectos nocivos inflamatorios, oncológicos o congénitos, que generan un conjunto de implicaciones biopsicosociales. Objetivo: Identificar algunas percepciones y representaciones sociales construidas por personas con ostomías de eliminación en torno a su condición. Metodología: Se trata de un estudio descriptivo y exploratorio, con enfoque cualitativo, basado en la teoría de las representaciones sociales, realizado a través de relatos de pacientes con ostomía de eliminación en una consulta ambulatoria de enfermería en estomaterapia, procesados mediante el software IRaMuTeQ. Resultados: Se infieren una serie de interpretaciones que revelan los desafíos y consecuencias que imponen estos dispositivos, como barreras sociales, laborales y alimentarias, que se suman a los estigmas y sentimientos negativos asociados a la autoimagen y la autopercepción en la conciencia de estos individuos, así como las potencialidades observadas como familia, comunidad y espiritualidad de los participantes, que requieren comprensión por parte de los profesionales de la salud. Consideraciones finales: El trabajo expresa representaciones construidas en torno a las percepciones de algunos pacientes sobre el uso de la ostomía, que pueden ayudar a comprender ese estado, apoyando una práctica profesional más empática y sintonizada con los aspectos psicológicos, sociales y espirituales

Abstract: Introduction: Elimination ostomies are defined as an externalization of part of the digestive system due to harmful inflammatory, oncological or congenital effects, generating a set of biopsychosocial implications. Objective: To identify some perceptions and social representations constructed by people with elimination ostomies around their condition. Methodology: This is a descriptive and exploratory study, with a qualitative approach, based on the Theory of Social Representations, carried out through reports from patients with elimination stoma in an outpatient nursing consultation in stoma therapy, processed using the IRaMuTeQ software. Results: A series of interpretations are inferred that reveal the challenges and consequences imposed by these devices, such as social, work and food barriers, which add to the stigmas and negative feelings associated with self-image and self-perception in the consciousness of these individuals, as well as the potentialities observed such as the family, community and spirituality of the participants, requiring understanding from health professionals. Final Considerations: The work expresses representations built around some patients’ perceptions regarding the use of a stoma, which can help in understanding this state, supporting a more empathetic professional practice that is attuned to psychological, social and spiritual aspects

Resumo: Introdução: As estomias de eliminação são definidas como uma externalização de parte do sistema digestivo em razão de agravos inflamatórios, oncológicos ou congênitos, gerando um conjunto de implicações biopsicossociais Objetivo: Identificar algumas percepções e representações sociais construídas por pessoas com estomias de eliminação em torno da sua condição. Metodologia: Trata-se de um estudo descritivo e exploratório, de abordagem qualitativa, pautado na Teoria das Representações Sociais, realizado através de relatos de pacientes com estomias de eliminação em uma consulta ambulatorial de enfermagem em estomaterapia, processados por meio do software IRaMuTeQ. Resultados: infere-se uma série de interpretações que revelam os desafios e as consequências impostas por esses dispositivos, a exemplo as barreiras sociais, laborais e alimentares, que somam-se aos estigmas e sentimentos negativos associados à autoimagem e a autopercepção na consciência desses indivíduos, bem como as potencialidades observadas como a família, comunidade e a espiritualidade dos participantes, exigindo dos profissionais de saúde a compreensão. Considerações finais: O trabalho expressa representações construídas em torno de algumas percepções dos pacientes em torno do uso da estomia, podendo auxiliar na compreensão desse estado, embasando uma prática profissional mais empática e antenada aos aspectos psicológicos, sociais e espirituais

Resumo Microtia e atresia congénita do canal auditivo externo (CAE) são malformações congénitas do ouvido externo que se encontram muitas vezes associadas. A microtia resulta de uma malformação do pavilhão auricular enquanto a atresia congénita diz respeito a um encerramento total ou parcial do CAE. O desafio para os Otorrinolaringologistas reside no tratamento, que engloba a eventual cirurgia reconstrutiva e a reabilitação auditiva. Cada caso é único, exigindo uma abordagem personalizada por uma equipa especializada, com otorrinolaringologistas e cirurgiões plásticos. Apresentamos um caso de uma mulher de 62 anos com microtia e atrésia congénita do CAE direito, com antecedentes de cirurgia reconstrutiva do pavilhão auricular, no qual foi decidida reabilitação auditiva com implante osteointegrado.

ABSTRACT Microtia and congenital atresia of the external auditory canal (EAC) are congenital malformations of the external ear that are often associated. Microtia results from a malformation of the auricle, while congenital atresia is a total or partial occlusion of the EAC. The challenge for the otolaryngologist is the management, which may include reconstructive surgery and auditory rehabilitation. Each case is unique and requires an individualized approach by a specialized team of otolaryngologists and plastic surgeons. We present the case of a 62-year-old woman with microtia and congenital atresia of the right EAC, with a history of reconstructive surgery of the pinna, in which auditory rehabilitation with an osseointegrated implant was chosen.

RESUMO A doença renal crônica (DRC) representa um dos principais problemas de saúde pública da atualidade. A dosagem da creatinina sérica e a estimativa da taxa de filtração glomerular (TFG) são as principais ferramentas para avaliação da função renal. Para a estimativa da TFG, existem diversas equações, sendo a mais recomendada a CKD-EPI (Chronic Kidney Disease – Epidemiology). Existem ainda algumas controvérsias com relação à dosagem da creatinina sérica e da estimativa da TFG, uma vez que vários fatores podem interferir nesse processo. Uma importante mudança recente foi a retirada da correção por raça das equações para estimativa da TFG, que superestimavam a função renal, e consequentemente retardavam a implementação de tratamentos como diálise e transplante renal. Neste documento de consenso da Sociedade Brasileira de Nefrologia e Sociedade Brasileira de Patologia Clínica e Medicina Laboratorial são revisados os principais conceitos relacionados à avaliação da função renal, possíveis controvérsias existentes e recomendações para a estimativa da TFG na prática clínica. DRC (DRC atualidade (TFG CKDEPI CKD EPI Chronic Epidemiology. Epidemiology . Epidemiology) processo clínica

ABSTRACT Chronic kidney disease (CKD) represents one of today’s main public health problems. Serum creatinine measurement and estimation of the glomerular filtration rate (GFR) are the main tools for evaluating renal function. There are several equations to estimate GFR, and CKD-EPI equation (Chronic Kidney Disease – Epidemiology) is the most recommended one. There are still some controversies regarding serum creatinine measurement and GFR estimation, since several factors can interfere in this process. An important recent change was the removal of the correction for race from the equations for estimating GFR, which overestimated kidney function, and consequently delayed the implementation of treatments such as dialysis and kidney transplantation. In this consensus document from the Brazilian Societies of Nephrology and Clinical Pathology and Laboratory Medicine, the main concepts related to the assessment of renal function are reviewed, as well as possible existing controversies and recommendations for estimating GFR in clinical practice. CKD (CKD todays today s problems (GFR CKDEPI EPI Epidemiology process transplantation Medicine reviewed practice

ABSTRACT Introduction Chemotherapy and radiation therapy are considered standard treatments for stage II seminoma patients; however, these therapies are associated with long-term toxicities. Recently, retroperitoneal lymph node dissection has emerged as an alternative strategy, and the first three phase II trials were published in 2023 with promising results. The present study conducted a systematic review and meta-analysis to evaluate this surgery as an alternative treatment for stage IIA/B seminoma patients. Purpose Seminomas are the most common testicular tumors, often affecting young adult males. Standard treatments for stage II seminomas include chemotherapy and radiation therapy, but these therapies are associated with long-term toxicities. Thus, identifying alternative strategies is paramount. Herein, we conducted a systematic review and meta-analysis to appraise the efficacy and safety of retroperitoneal lymph node dissection (RPLND) for treating this condition. Methods We systematically searched the PubMed, Embase, and Cochrane databases for studies evaluating RPLND as a primary treatment for stage II A/B seminomas. Using a random-effects model, single proportion and means and pooled 2-year recurrence-free survival rates with hazard rates and 95% CI were calculated. Results Seven studies were included, comprising 331 males with stage II seminomas. In the pooled analysis, the recurrence rate was 17.69% (95% CI 12.31–24.75), and the 2-year RFS rate was 81% (95% CI 0.77–0.86). The complication rate was 9.16% (95% CI 6.16–13.42), the Clavien–Dindo > 2 complication rate was 8.83% (95% CI 5.76–13.31), and the retrograde ejaculation rate was 7.01% (95% CI 3.54–13.40). The median operative time was 174.68 min (95% CI 122.17–249.76 min), median blood loss was 105.91 mL (95% CI 46.89–239.22 mL), and patients with no evidence of lymph node involvement ranged from 0–16%. Conclusions Primary RPLNDs for treating stage IIA/B seminomas have favorable RFS rates, with low complication and recurrence rates. These findings provide evidence that this surgery is a viable alternative therapy for these patients. however longterm long term toxicities Recently strategy 202 results metaanalysis meta analysis IIAB IIA B tumors Thus paramount Herein (RPLND condition PubMed Embase AB A randomeffects random effects model 2year year recurrencefree free 95 calculated included 33 1769 17 69 17.69 (95 12.31–24.75, 12312475 12.31–24.75 , 12 31 24 75 12.31–24.75) 81 0.77–0.86. 077086 0.77–0.86 . 0 77 86 0.77–0.86) 916 9 16 9.16 6.16–13.42, 6161342 6.16–13.42 6 13 42 6.16–13.42) ClavienDindo Clavien Dindo 883 8 83 8.83 5.76–13.31, 5761331 5.76–13.31 5 76 5.76–13.31) 701 7 01 7.01 3.54–13.40. 3541340 3.54–13.40 3 54 40 3.54–13.40) 17468 174 68 174.6 1221724976 122 249 122.17–249.7 min, min) 10591 105 91 105.9 468923922 46 89 239 22 46.89–239.2 mL, mL) 016 0–16% 20 176 1 17.6 (9 1231247 12.31–24.7 07708 0.77–0.8 9.1 616134 6.16–13.4 4 88 8.8 576133 5.76–13.3 70 7.0 354134 3.54–13.4 1746 174. 122172497 122.17–249. 1059 10 105. 46892392 23 46.89–239. 0–16 17. ( 123124 12.31–24. 0770 0.77–0. 9. 61613 6.16–13. 8. 57613 5.76–13. 7. 35413 3.54–13. 12217249 122.17–249 4689239 46.89–239 0–1 12312 12.31–24 077 0.77–0 6161 6.16–13 5761 5.76–13 3541 3.54–13 1221724 122.17–24 468923 46.89–23 0– 1231 12.31–2 07 0.77– 616 6.16–1 576 5.76–1 354 3.54–1 122172 122.17–2 46892 46.89–2 123 12.31– 0.77 61 6.16– 57 5.76– 35 3.54– 12217 122.17– 4689 46.89– 12.31 0.7 6.16 5.76 3.54 1221 122.17 468 46.89 12.3 0. 6.1 5.7 3.5 122.1 46.8 12. 6. 5. 3. 122. 46.

ABSTRACT Objective: The objective of this narrative review is to discuss the current state of research funding in Brazil. Materials and Methods: This study is based on the most recent edition of the course Funding for Research and Innovation in the University of Sao Paulo School of Medicine which was a three-day course with 12 hours of instruction. The course brought together leading experts in the field to comprehensively discuss the current state of research funding in Brazil. Each speaker provided a presentation on a specific topic related to research funding. After the workshop, speakers assembled relevant topics in this manuscript. Results: collaborative research is critical for securing research funding. It optimizes proposal competitiveness, amplifies societal impact, and manages risks effectively. As such, fostering and supporting these collaborations is paramount for both researchers and funding agencies. To maintain the highest integrity in research, investigators involved in these collaborations must disclose any relationships that could potentially influence the outcomes or interpretation of their projects. Conclusions: In Brazil, the mainstay of research funding stems from public entities, with agencies such as CNPq, CAPES, and state bodies like FAPESP, FAPERJ, FAPEMIG and others at the forefront. Concurrently, industry funding offers viable pathways, especially through industry-sponsored studies, investigator-led projects, and collaborative initiatives. The Brazilian funding landscape is further enriched by innovative platforms, including crowdfunding and the contributions of institutions like the Serrapilheira Institute. Internationally, esteemed organizations such as the National Institutes of Health (NIH) and the Bill & Melinda Gates Foundation stand out as potential funders. Objective Brazil Methods threeday three day 1 instruction workshop manuscript Results competitiveness impact effectively projects Conclusions entities CNPq CAPES FAPESP FAPERJ forefront Concurrently pathways industrysponsored sponsored studies investigatorled investigator led initiatives platforms Institute Internationally NIH (NIH funders

RESUMO Diferenciar a dor/desordens odontogénicas orofaciais da dor/desordens as sociadas á sinusite maxilar é importante para evitar procedimentos odontológicos desnecessários e para encaminhar adequadamente os pacientes aos colegas/dentistas e vice-versa. Objetivo Analisar a associagdo entre lesoes apicais e alteragóes sinusais e avaliar a concordáncia entre os diagnósticos de um endodontista, um radiologista, um cirurgido bucomaxilofacial e um otorrinolaringologista. Material e Método foram avaliadas 385 imagens. Resultados Aslesoes apicais foram observadas em 36,10% dos casos de sinusite, em 73,8% dos casos de sinusite unilateral, em 48,7% dos casos de descontinuidade do assoalho do seio e em 67,2%odos casos em que o tratamento endodontico havia sido realizado. A concordancia entre os diagnósticos feitos pelo endodontista e os feitos pelos outros pesquisadores foi alta para a maioria das variáveis do estudo (k &gt; 0,60). As excegoes foram o espessamento da mucosa, para o qual a concordáncia entre o endodontista e os outros pesquisadores foi intermediária (k=0,397) e a presenga delesoes periapicais (k=0,010), tratamento endodontico prévio (k=0,013) e espessura da mucosa (k=0,024), para os quais a concordáncia entre endodontistas e radiologistas foi baixa. Conclusoes Houve uma associagdo entre as alteragóes sinusais e aslesoes apicais.

ABSTRACT Differentiating orofacial odontogenic pain/disorders from pain/disorders associated with maxillary sinusitis is important to avoid unnecessary dentalprocedures and to properly refer patients to colleagues/dentists and vice versa. Aim To analyze the association between apical lesions and sinus changes and to evaluate the agreement between the diagnoses of an endodontist, a radiologist, an oral and maxillofacial surgeon, and an otolaryngologist. Materials and Method 385 axial, coronal, and sagittal MSCT scans were selected using an image archiving andcommunication system (PACS). The examinations had been performed between 2018 and 2022. Results Apical lesions were observed in 36.10% of sinusitis cases, 73.8% of unilateralsinusitis cases, 48.7% of sinus floor discontinuity cases, and 67.2% of cases in which endodontic treatment had been performed. Agreement between the diagnoses made by the endodontist and those made by the other investigators was high for most study variables (k &gt; 0.60). The exceptions were mucosal thickening, for which agreement between the endodontist and the other investigators was intermediate (k=0.397), and the presence of periapicallesions (k=0.010), previous endodontic treatment (k=0.013), and mucosal thickness (k=0.024), for which agreement between endodontists and radiologists was low. Conclusions: There was an association between sinus changes and apical lesions.

ABSTRACT BACKGROUND: Abnormal uterine bleeding (AUB) is a common condition, and the Menstrual Bleeding Questionnaire (MBQ) is used for its assessment. OBJECTIVES: To translate, assess the cut-off point for diagnosis, and explore psychometric properties of the MBQ for use in Brazilian Portuguese. DESIGN AND SETTING: Prospective cohort study including 200 women (100 with and 100 without AUB) at a tertiary referral center. METHODS: MBQ translation involved a pilot-testing phase, instrument adjustment, data collection, and back-translation. Cut-off point was obtained using receiver operating curve analysis. Menstrual patterns, impact on quality of life due to AUB, internal consistency, test-retest, responsiveness, and discriminant validity were assessed. For construct validity, the Pictorial Blood Assessment Chart (PBAC) and World Health Organization Quality of Life – abbreviated version (WHOQOL-BREF) were applied. RESULTS: Women with AUB were older, had higher body mass indices, and had a worse quality of life during menstruation. Regarding the MBQ's psychometric variables, Cronbach's alpha coefficient was > 0.70 in all analyses, high intraclass correlation coefficient was found in both groups; no ceiling and floor effects were observed, and construct validity was demonstrated (correlation between MBQ score, PBAC score, and clinical menstrual cycle data). No difference between MBQ and PBAC scores were perceived after the test-retest. Significant differences were found between MBQ and PBAC scores before and after treatment. An MBQ score ≥ 24 was associated with a high probability of AUB; accuracy of 98%. CONCLUSION: The MBQ is a reliable questionnaire for Brazilian women. The cut-off ≥ 24 shows high accuracy to discriminate AUB. BACKGROUND (AUB condition (MBQ assessment OBJECTIVES translate cutoff cut off diagnosis Portuguese SETTING 20 (10 10 center METHODS pilottesting pilot testing phase adjustment collection backtranslation. backtranslation back translation. back-translation Cutoff Cut analysis patterns consistency testretest, testretest test retest, retest test-retest responsiveness assessed (PBAC WHOQOLBREF WHOQOL BREF (WHOQOL-BREF applied RESULTS older indices menstruation MBQs s variables Cronbachs Cronbach 070 0 70 0.7 analyses groups observed data. . data) testretest. retest. treatment 2 98 98% CONCLUSION (1 1 07 7 0. 9 (

Abstract This article presents the incorporation of information and communication technologies on the teaching-learning process of geotechnical engineering to improve the quality of education and provide practical knowledge to civil engineering students. The content of this paper is divided into three main modules, which are: Treatment of laboratory tests results, Slope stability and Rock mass stability. For this, some software were used, including 2D limit equilibrium stability analysis, stability analysis of rock wedges and a dynamic mathematics, to obtain and analyze soil shear strength parameters, among others. Furthermore, a digital tool was developed to analyze the results gathered in compaction, one-dimensional consolidation, and direct soil shear tests, in order to clarify the relationship between theoretical concepts and practical results of the tests and analyses and to help students on doubts, in addition to increase their interest and motivation to perform the complete interpretation of the collected data. The activities were conducted in classes of geotechnical disciplines of the undergraduate course in Civil Engineering at the Federal University of Viçosa, aiming to promote active learning and improve teaching quality. Based on the results of an applied feedback questionnaire, it was observed that most students were satisfied with the resources used in the classroom, demonstrating that the implemented digital tools work as a didactic instrument that facilitates learning and comprehension of practical problems, in addition to enabling the resolution of several geotechnical engineering problems much more quickly and efficiently. teachinglearning modules are D mathematics parameters others Furthermore compaction onedimensional one dimensional consolidation doubts data Viçosa questionnaire classroom efficiently

RESUMO: A seleção de plantas conduzida em pomares comerciais é baseada principalmente nas características da planta. Este trabalho teve como objetivo caracterizar e selecionar genótipos de aceroleira com características promissoras para cultivo na região do Vale do Gurguéia, Piauí. Foram utilizados 25 genótipos, sendo 15 clones (CL 03, CL 08, CL 09, CL 12, CL 13, CL 14, CL 20, CL 23, CL 26, CL 27, CL 30, CL 31, CL 33, CL 36 e CL 38) e 10 cultivares (BRS 235, BRS 236, BRS 237, BRS 238, BRS 366, Sertaneja, Costa Rita, Morena, Tropicana e Junko). O experimento foi instalado no delineamento de blocos casualizados com três blocos e três plantas por unidade experimental no espaçamento de 4 m x 3 m. Um total de 40% dos genótipos avaliados apresentou formato guarda-chuva, 36% formato semiaberto e 24% formato aberto. Os clones 09, 14 e 12 apresentaram o maior potencial de cultivo da região, com produção mensal de 5,01, 4,30 e 3,70 kg planta-¹ por ano e produtividade de 4,16, 3,59 e 3,08 ton ha-¹, respectivamente. O clone 27, as cultivares BRS 236 e BRS 235 e o clone 14 foram os genótipos mais precoces, requerendo 1.503,3, 1.535,6, 1.686,6 e 1.686,6 DD, respectivamente, para completar seu ciclo. Os clones 09 e 14 se destacaram em relação aos demais e são potencialmente promissores para cultivo na região do Vale do Gurgueia. RESUMO planta Gurguéia Piauí 2 1 03 08 13 20 23 26 27 30 31 33 38 237 238 366 Sertaneja Rita Morena Junko. Junko . Junko) 40 guardachuva, guardachuva guarda chuva, chuva guarda-chuva 24 aberto 501 5 01 5,01 430 4,3 370 70 3,7 planta¹ ¹ planta- 416 16 4,16 359 59 3,5 308 3,0 ha¹, ha¹ ha ¹, ha-¹ respectivamente precoces 15033 503 1.503,3 15356 535 6 1.535,6 16866 686 1.686, DD ciclo 0 Gurgueia 50 5,0 43 4, 37 7 3, 41 4,1 35 ha- 1503 1.503, 1535 53 1.535, 1686 68 1.686 5, 150 1.503 153 1.535 168 1.68 1.50 1.53 1.6 1.5 1.

ABSTRACT: Plant selection conducted in commercial orchards is mainly based on plant features. This study characterizes and selects acerola tree genotypes with promising features for cultivation in the Gurguéia Valley region, Piauí. Twenty-five genotypes were used, consisting of 15 clones (CL 03, CL 08, CL 09, CL 12, CL 13, CL 14, CL 20, CL 23, CL 26, CL 27, CL 30, CL 31, CL 33, CL 36, and CL 38) and 10 cultivars (BRS 235, BRS 236, BRS 237, BRS 238, BRS 366, Sertaneja, Costa Rita, Morena, Tropicana, and Junko). The experiment was set up in a randomized block design with three blocks and three plants per experimental unit in 4 m x 3 m spacing. A total of 40% of the genotypes evaluated showed an umbrella shape, 36% showed a semi-open shape, and 24% showed an open shape. Clones 09, 14, and 12 presented the highest cultivation potential in the region, with monthly production of 5.01, 4.30, and 3.70 kg plant-¹ per year and productivity of 4.16, 3.59, and 3. 08-ton ha-¹, respectively. Clone 27, cultivars BRS 236 and BRS 235, and clone 14 were the earliest genotypes, requiring 1,503.3, 1,535.6, 1,686.6, and 1,686.6 DD; respectively, to complete their cycle. Clones 09 and 14 stood out from the others and are potentially promising for cultivation in the Gurgueia Valley region. ABSTRACT region Piauí Twentyfive Twenty five used 1 03 08 13 20 23 26 27 30 31 33 36 38 235 237 238 366 Sertaneja Rita Morena Tropicana Junko. Junko . Junko) spacing 40 shape semiopen semi 24 501 5 01 5.01 430 4.30 370 70 3.7 plant¹ ¹ plant- 416 16 4.16 359 59 3.59 08ton ton ha¹, ha¹ ha ¹, ha-¹ respectively 15033 503 1,503.3 15356 535 6 1,535.6 16866 686 1,686. DD cycle 0 2 50 5.0 43 4.3 37 7 41 4.1 35 3.5 ha- 1503 1,503. 1535 53 1,535. 1686 68 1,686 5. 4. 150 1,503 153 1,535 168 1,68 1,50 1,53 1,6 1,5 1,

As ondas eletromagnéticas estão presentes em diversas aplicações tecnológicas do cotidiano, desde telecomunicações até questões relacionadas ao aquecimento global e cuidados com a saúde. Assim, a inclusão de produtos educacionais experimentais, expositivos e lúdicos sobre este assunto não pode ser negligenciada no ensino formal. O presente trabalho apresenta a construção de um produto educacional (PE) experimental e interativo que apresenta a dependência da cor em relação à luz visível, assim como o fenômeno da luminescência em alguns materiais quando expostos à radiação ultravioleta. Trata-se de uma câmara escura equipada com lâmpadas nas cores, vermelha, verde e azul, além de uma fonte ultravioleta (UV). O dispositivo foi construído utilizando materiais acessíveis e de baixo custo. As lâmpadas podem ser ligadas independentemente ou em conjunto, e a percepção da cor do objeto dependerá das cores da luz que o ilumina. Portanto, o PE pode ser empregado no estudo da teoria das cores. A inclusão da fonte UV permite a observação da luminescência de objetos quando expostos a ela, fenômeno frequentemente retrato em filmes e séries policiais. Essas substâncias fotoluminescentes estão presentes em diversos materiais, como papel sulfite e sabão em pó. cotidiano saúde Assim experimentais formal (PE visível Tratase Trata se vermelha azul UV. . (UV) custo conjunto ilumina Portanto ela policiais pó (UV

Electromagnetic waves play a crucial role in various technological applications in our daily lives, ranging from telecommunications to issues related to global warming and healthcare. Therefore, the inclusion of experimental, expository, and playful educational products on this subject cannot be neglected in formal education. This study introduces the development of an experimental and interactive educational product (EP) designed to elucidate the relationship between color and visible light, as well as the luminescent phenomenon exhibited by certain materials when exposed to ultraviolet radiation (UV). The EP is cost-effective and accessible, comprising a dark box equipped with red, green, blue, and UV lamps. These lamps can be turned on individually or collectively, influencing the perceived color of an object based on the illuminating light’s color. Thus, the EP serves as a valuable resource for studying the theory of colors. The inclusion of a UV light source allows for the observation of luminescent properties in objects exposed to it, a feature commonly portrayed in crime movies and TV series. Photoluminescent substances are present in various materials, including sulfite paper and laundry detergent. Consequently, this EP emerges as an effective tool for introducing quantum mechanics concepts in the classroom. lives healthcare Therefore expository education (EP UV. . (UV) costeffective cost accessible red green blue collectively lights s Thus colors it series detergent Consequently classroom (UV

Objective: We aimed to translate and determine cultural validity of the Vaginal Changes Sexual and Body Esteem Scale (VSBE) for Brazilian Portuguese language in postpartum women who underwent vaginal delivery with or without perineal laceration and cesarean section. Methods: A cross-sectional study conducted virtually, with online data collection through a survey with 234 postpartum women of 975 that were invited. Clinical, sociodemographic, and psychometric variables from the VSBE questionnaire were analyzed (content validity index, internal consistency, test-retest reliability, construct/structural and discriminant validity). Multivariate analysis was performed to explore associated factors with the presence of perineal laceration. Results: One-hundred fifty-eight women experienced vaginal delivery, of which 24.79% had an intact perineum, 33.33% had perineal laceration, and 9.4% underwent episiotomy; and 76 participants had cesarean sections. Women with perineal laceration were older, presented dyspareunia and previous surgeries than women without perineal laceration (p<0.05). For VSBE, a high internal consistency (Cronbach's α > 0.7) was observed, but it did not correlate with Body Attractiveness Questionnaire and Female Sexual Function Index; however, it correlated with the presence of women sutured for perineal laceration. Moreover, VSBE presented good structural validity with two loading factors after exploratory factor analysis. VSBE also demonstrated discriminant validity between the presence or absence of perineal laceration. The presence of urinary incontinence (UI) (OR=2.716[1.015-4.667];p=0.046) and a higher VSBE total score (OR=1.056[1.037-1.075];p<0.001) were the only factors associated with perineal laceration. Conclusion: Vaginal Changes Sexual and Body Esteem Scale demonstrated appropriate translation and good internal consistency, discriminant/construct validity and reliability. Vaginal Changes Sexual and Body Esteem Scale total score and presence of UI were associated with women that underwent perineal laceration. Objective (VSBE section Methods crosssectional cross sectional virtually 23 97 invited Clinical sociodemographic content index testretest test retest reliability constructstructural construct validity. . validity) Results Onehundred One hundred fiftyeight fifty eight 2479 24 79 24.79 perineum 3333 33 33.33 94 9 4 9.4 episiotomy 7 sections older p<0.05. p005 p p<0.05 0 05 (p<0.05) Cronbachs Cronbach s 0.7 07 observed Index however Moreover (UI OR=2.7161.0154.667p=0.046 OR271610154667p0046 ORp OR=2.716 1.015 4.667 p=0.046 OR 2 716 1 015 667 046 (OR=2.716[1.015-4.667];p=0.046 OR=1.0561.0371.075p<0.001 OR105610371075p0001 OR=1.056 1.037 1.075 p<0.001 056 037 075 001 (OR=1.056[1.037-1.075];p<0.001 Conclusion discriminantconstruct 247 24.7 333 3 33.3 9. p00 p<0.0 (p<0.05 0. 7161 0154 667p OR=2.7161.0154.667p=0.04 OR271610154667p004 OR2716 OR=2.71 1015 1.01 4667 4.66 p0046 p=0.04 71 01 66 04 (OR=2.716[1.015-4.667];p=0.04 0561 0371 075p OR=1.0561.0371.075p<0.00 OR105610371075p000 OR1056 OR=1.05 1037 1.03 1075 1.07 p0001 p<0.00 03 00 (OR=1.056[1.037-1.075];p<0.00 24. 33. p0 p<0. (p<0.0 OR=2.7161.0154.667p=0.0 OR271610154667p00 OR271 OR=2.7 101 1.0 466 4.6 p004 p=0.0 6 (OR=2.716[1.015-4.667];p=0.0 OR=1.0561.0371.075p<0.0 OR105610371075p00 OR105 OR=1.0 103 107 p000 (OR=1.056[1.037-1.075];p<0.0 p<0 (p<0. OR=2.7161.0154.667p=0. OR271610154667p0 OR27 OR=2. 10 1. 46 4. p=0. (OR=2.716[1.015-4.667];p=0. OR=1.0561.0371.075p<0. OR105610371075p0 OR10 OR=1. (OR=1.056[1.037-1.075];p<0. p< (p<0 OR=2.7161.0154.667p=0 OR271610154667p OR2 OR=2 p=0 (OR=2.716[1.015-4.667];p=0 OR=1.0561.0371.075p<0 OR105610371075p OR1 OR=1 (OR=1.056[1.037-1.075];p<0 (p< OR=2.7161.0154.667p= OR= p= (OR=2.716[1.015-4.667];p= OR=1.0561.0371.075p< (OR=1.056[1.037-1.075];p< (p OR=2.7161.0154.667p (OR=2.716[1.015-4.667];p OR=1.0561.0371.075p (OR=1.056[1.037-1.075];p

Objectives: To estimate the prevalence of antidepressant use in Brazil. Methods: We conducted a systematic review with searches in MEDLINE, Embase, Scopus, LILACS, and SciELO up to May 2023. Two researchers independently selected studies, extracted data, and assessed the methodological quality. We pooled the prevalence of antidepressant use using meta-analyses of proportions (Freeman-Tukey transformation) and estimated heterogeneity by the I2 statistic. OR meta-analyses of antidepressant use by sex were calculated (men as reference) and between-study variation was explored by meta-regressions. Results: Out of 3,299 records retrieved, 23 studies published in 28 reports were included, with a total of 75,061 participants. The overall prevalence of antidepressant use was 4.0% (95%CI 2.7-5.6%; I2 = 98.5%). Use of antidepressants in the previous 3 days was higher in women (12.0%; 95%CI 9.5-15.1%; I2 = 0%) than men (4.6%; 95%CI 3.1-6.8%; I2 = 0%) (p < 0.001; OR = 2.82; 95%CI 1.72-4.62). Gender differences were particularly higher for antidepressant use in the previous year (women: 2.3%; 95%CI 1.6-3.1; I2 = 37.6% vs. men: 0.5%; 95%CI 0.2-1.0%; I2 = 0%, p < 0.001; OR = 4.18; 95%CI 2.10-8.30). Between-study variation in the overall prevalence of antidepressant use significantly increased with mean participant age (p = 0.035; residual I2 = 0%; regression coefficient = 0.003). Conclusion: Four out of every 100 Brazilians used antidepressants in this 3-decade assessment. Use increased with age and was more prevalent in women compared to men. Registration number: PROSPERO CRD42022345332. Objectives Brazil Methods MEDLINE Embase Scopus LILACS 2023 data quality metaanalyses meta analyses FreemanTukey Freeman Tukey transformation I statistic reference betweenstudy between study metaregressions. metaregressions regressions. regressions meta-regressions Results 3299 299 3,29 retrieved 2 included 75061 75 061 75,06 participants 40 4 0 4.0 95CI CI 95 2.75.6% 2756 2.7 5.6% 7 5 6 2.7-5.6% 98.5%. 985 98.5% . 98 98.5%) 12.0% 120 12 (12.0% 9.515.1% 95151 9.5 15.1% 9 15 1 9.5-15.1% 0% 4.6% 46 (4.6% 3.16.8% 3168 3.1 6.8% 8 3.1-6.8% 0.001 0001 001 2.82 282 82 1.724.62. 172462 1.72 4.62 72 62 1.72-4.62) (women 2.3% 1.63.1 1631 1.6 1.6-3.1 376 37 37.6 vs 0.5% 05 0.21.0% 0210 0.2 1.0% 0.2-1.0% 4.18 418 18 2.108.30. 210830 2.10 8.30 10 30 2.10-8.30) Betweenstudy Between 0.035 0035 035 0.003. 0003 0.003 003 0.003) Conclusion 3decade decade assessment number CRD42022345332 CRD 202 329 29 3,2 7506 06 75,0 4. 2.75.6 275 27 2. 56 5.6 2.7-5.6 98.5 12.0 (12.0 515 9.515.1 9515 9. 151 15.1 9.5-15.1 4.6 (4.6 16 3.16.8 316 31 3. 68 6.8 3.1-6.8 0.00 000 00 2.8 724 1.724.62 17246 172 1.7 462 1.72-4.62 2.3 63 1.63. 163 1. 1.6-3. 37. 0.5 21 0.21.0 021 02 0. 1.0 0.2-1.0 4.1 41 108 2.108.30 21083 210 2.1 830 8.3 2.10-8.30 0.03 03 CRD4202234533 20 32 3, 750 75, 2.75. 5. 2.7-5. 98. 12. (12. 51 9.515. 951 15. 9.5-15. (4. 3.16. 6. 3.1-6. 0.0 1.724.6 1724 17 1.72-4.6 1.63 1.6-3 0.21. 0.2-1. 2.108.3 2108 83 8. 2.10-8.3 CRD420223453 2.75 2.7-5 (12 9.515 9.5-15 (4 3.16 3.1-6 1.724. 1.72-4. 1.6- 0.21 0.2-1 2.108. 2.10-8. CRD42022345 2.7- (1 9.51 9.5-1 ( 3.1- 1.724 1.72-4 0.2- 2.108 2.10-8 CRD4202234 9.5- 1.72- 2.10- CRD420223 CRD42022 CRD4202 CRD420 CRD42 CRD4