ABSTRACT Given the large differences in the results of inoculation and co-inoculation in the bean crop, an experiment in cultivating winter beans was carried out in 2019 under greenhouse conditions with the aim of evaluating the performance of the beans and a possible increase in plant growth and grain production, using seeds inoculated or co-inoculated with Rhizobium tropici and Azospirillum brasilense, with and without fungicide and/or insecticide, in sandy and clayey soils. A total of 112 pots were used, and 14 treatments were applied in a completely randomised experimental design, with four replications. The Scott-Knott test was used to analyse the results, and showed that whether using untreated seeds or carrying out complete chemical treatment with fungicide and insecticide plus co-inoculation with R. tropici and A. brasilense, winter bean production was reduced in clayey soil, while the joint use of fungicide and insecticide, fungicide and R. tropici, or fungicide, insecticide and R. tropici, favoured shoot development. Inoculating with A. brasilense, without R. tropici and with insecticide, or insecticide and fungicide, favoured greater root growth in clayey soil. In sandy soil, grain production was higher using seeds treated solely with insecticide, solely with R. tropici, or with a combination of both. Production was lower in the joint treatment with fungicide, insecticide and the co-inoculation of bacteria, or when using insecticide together with A. brasilense. coinoculation co crop 201 coinoculated brasilense andor soils 11 1 design replications ScottKnott Scott Knott R soil development both bacteria 20 2

Resumo O estudo analisou como as inflexões político-econômicas de financiamento e de estruturação do Sistema Único de Saúde podem ter afetado as condições de implementação de ações de prevenção e controle da obesidade (PCO) na atenção primária à saúde (APS) no estado do Rio de Janeiro (ERJ) entre 2014 e 2021. Fundamentou-se em referenciais de análise de políticas, considerando contexto de implementação, antecedentes históricos, mecanismos de indução e incentivos governamentais para o desenvolvimento das ações de PCO. Baseou-se em dois projetos realizados nos 92 municípios do ERJ entre 2014 e 2018 (PPSUS-ERJ) e 2019-2021 (PEO-ERJ), pautados em análise documental, entrevistas e grupos focais com profissionais e gestores da APS. Até 2016, percebe-se os impactos positivos da estruturação da APS e dos mecanismos de indução federais. No entanto, as inflexões na expansão e no financiamento da APS contribuíram para o enfraquecimento de unidades, equipes e estratégias, além de uma retração de recursos para as ações estaduais e municipais. Entre 2016-2018, a crise política e financeira do ERJ foi potencializada pelas crises nacionais, e os contrapontos positivos desde então foram os mecanismos de indução e recursos federais que permaneceram, além das áreas técnicas da SES-ERJ e do cofinanciamento estadual.

Abstract The present study aimed to analyze how these changes, both at the national and state levels, could affect the conditions of the implementation of obesity prevention and control (OCP) actions in primary health care (PHC) in the Rio de Janeiro State from 2014 to 2021. This study was based on policy analysis methods that emphasize the understanding of the implementation contexts, as well as the induction mechanisms and government incentives for the development of actions and integration of two projects that analyzed the OPC actions in PHC in the 92 municipalities of RJS between 2014 and 2018 (PPSUS-RJS) and between 2019 and 2021 (PEO-RJS). The results indicate that, by 2016, it was possible to observe the positive impacts of the structuring of PHC and the federal induction mechanisms in RJS. However, inflections in the expansion and funding of PHC contributed to the weakening of units, teams, and strategies, and led to retraction of resources for both state and municipal actions. Between 2016-2018, RJS’s political and financial scenario deteriorated due to national crises, and the positive counterpoints since then were the induction mechanisms and federal resources that remained, in addition to the technical areas of the RJS-HD and state co-financing resources.

Resumo O estudo analisou como as inflexões político-econômicas de financiamento e de estruturação do Sistema Único de Saúde podem ter afetado as condições de implementação de ações de prevenção e controle da obesidade (PCO) na atenção primária à saúde (APS) no estado do Rio de Janeiro (ERJ) entre 2014 e 2021. Fundamentou-se em referenciais de análise de políticas, considerando contexto de implementação, antecedentes históricos, mecanismos de indução e incentivos governamentais para o desenvolvimento das ações de PCO. Baseou-se em dois projetos realizados nos 92 municípios do ERJ entre 2014 e 2018 (PPSUS-ERJ) e 2019-2021 (PEO-ERJ), pautados em análise documental, entrevistas e grupos focais com profissionais e gestores da APS. Até 2016, percebe-se os impactos positivos da estruturação da APS e dos mecanismos de indução federais. No entanto, as inflexões na expansão e no financiamento da APS contribuíram para o enfraquecimento de unidades, equipes e estratégias, além de uma retração de recursos para as ações estaduais e municipais. Entre 2016-2018, a crise política e financeira do ERJ foi potencializada pelas crises nacionais, e os contrapontos positivos desde então foram os mecanismos de indução e recursos federais que permaneceram, além das áreas técnicas da SES-ERJ e do cofinanciamento estadual. políticoeconômicas político econômicas PCO (PCO (APS (ERJ 201 2021 Fundamentouse Fundamentou se políticas históricos Baseouse Baseou 9 PPSUSERJ PPSUS (PPSUS-ERJ 20192021 2019 2019-202 PEOERJ, PEOERJ PEO , (PEO-ERJ) documental 2016 percebese percebe entanto unidades estratégias municipais 20162018, 20162018 2018, 2016-2018 nacionais permaneceram SESERJ SES estadual 20 202 2019202 2019-20 (PEO-ERJ 2016201 2016-201 2 201920 2019-2 201620 2016-20 20192 2019- 20162 2016-2 2016-

Abstract The present study aimed to analyze how these changes, both at the national and state levels, could affect the conditions of the implementation of obesity prevention and control (OCP) actions in primary health care (PHC) in the Rio de Janeiro State from 2014 to 2021. This study was based on policy analysis methods that emphasize the understanding of the implementation contexts, as well as the induction mechanisms and government incentives for the development of actions and integration of two projects that analyzed the OPC actions in PHC in the 92 municipalities of RJS between 2014 and 2018 (PPSUS-RJS) and between 2019 and 2021 (PEO-RJS). The results indicate that, by 2016, it was possible to observe the positive impacts of the structuring of PHC and the federal induction mechanisms in RJS. However, inflections in the expansion and funding of PHC contributed to the weakening of units, teams, and strategies, and led to retraction of resources for both state and municipal actions. Between 2016-2018, RJS’s political and financial scenario deteriorated due to national crises, and the positive counterpoints since then were the induction mechanisms and federal resources that remained, in addition to the technical areas of the RJS-HD and state co-financing resources. changes levels OCP (OCP (PHC 201 contexts 9 PPSUSRJS PPSUS (PPSUS-RJS 202 PEORJS. PEORJS PEO . (PEO-RJS) 2016 However units teams strategies 20162018, 20162018 2018, 2016-2018 RJSs s crises remained RJSHD HD cofinancing co financing 20 (PEO-RJS 2016201 2016-201 2 201620 2016-20 20162 2016-2 2016-

ABSTRACT Sporotrichosis is caused by fungi belonging to the genus Sporothrix, and is generally acquired by traumatic inoculation. A 26-year-old man developed pustular lesions and a 6-kg weight loss after developing a lesion on his right hand 6 months previously. He was diagnosed with acquired human immunodeficiency syndrome (AIDS) and disseminated sporotrichosis cultures of bone and muscle biopsy and blood samples grew Sporothrix schenckii. The patient underwent reconstructive surgery and 9 months of treatment with amphotericin B and itraconazole, and showed complete wound healing and improved hand functionality. Suspicion of the disease is necessary in immunosuppressed patients living in endemic areas. inoculation 26yearold yearold 26 year old 6kg kg previously AIDS (AIDS schenckii itraconazole functionality areas 2

Resumen El mejoramiento genético de los cultivares de soja a lo largo de los años se ha centrado en aumentar la capacidad productiva y la tolerancia a algunos factores abióticos y bióticos. Sin embargo, durante la transferencia de genes de interés, algunos genes responsables de una menor tolerancia a los herbicidas pueden integrarse en el genoma del nuevo cultivar. El objetivo de este estudio fue evaluar la selectividad de las asociaciones de herbicidas apli cadas en la post-emergencia de tres cultivares de soja. El diseño experimental utilizado fue un bloque completamente al azar, con cuatro repeticiones. Los cultivares seleccionados fueron M7110 IPRO®, Foco IPRO® y Bônus IPRO®. Los herbicidas y las respectivas dosis (g a.i. ha-1) utilizados fueron: glyphosate (1176), glyphosate + bentazon (1176 + 600), glyphosate + fomesafen (1176 + 175), glyphosate + lactofen (1176 + 120), glyphosate + imazethapyr (1176 + 100), glyphosate + chlorimuron (1176 + 10), glyphosate + cloransulam (1176 + 39,5), y un control sin aplicación de herbicida. Se hizo una nota visual de intoxicación para cada tratamiento. Los componentes de crecimiento y rendimiento evaluados fueron: altura, rodal, peso de cien granos y rendimiento. La aplicación de herbicidas en post-emergencia no alteró la masa vegetal de los cultivares de soja. Además, estos herbicidas no redujeron el rendimiento de los cultivares M7110 IPRO® y Foco IPRO®. Tanto el glifosato aislado como mezclado con lactofen o imazethapyr redujeron el rendimiento del cultivar Bônus IPRO®.

Abstract The genetic improvement of soybean cultivars over the years has focused on increasing the yield potential and tolerance to some abiotic and biotic factors. However, during the transfer of genes of interest, some genes responsible for a lower tolerance to herbicides can be integrated into the genome of the new cultivar. Thus, the objective of this study was to evaluate the selectivity of herbicide associations applied in the postemergence period of three soybean cultivars. The experiment was conducted in a randomized completely block design, with four replications. The selected cultivars were M7110 IPRO®, Foco IPRO®, and Bônus IPRO®. The herbicides and the respective doses (g a.i. ha-1) used were glyphosate (1176), glyphosate + bentazon (1176 + 600), glyphosate + fomesafen (1176 + 175), glyphosate + lactofen (1176 + 120), glyphosate + imazethapyr (1176 + 100), glyphosate + chlorimuron (1176 + 10), glyphosate + cloransulam (1176 + 39.5), and a control without herbicide application. The visual note of intoxication was evaluated for each treatment. The components of growth and yield evaluated were height, stand, weight of one hundred grains, and yield. The application of postherbicide herbicides did not alter the plant stands of soybean cultivars. Additionally, these herbicides did not reduce the yield of the M7110 IPRO® and Foco IPRO® cultivars. Glyphosate isolated and in association with lactofen or imazethapyr reduced the grain yield of the Bônus IPRO® cultivar.

RESUMEN Introdución: En marzo de 2020, la OMS decretó oficialmente que el mundo atravesaba una pandemia, la del Covid-19. En mayo de 2022, en Brasil, se decretó el fin de las medidas para enfrentar la pandemia. En el año 2022, hubo un movimiento para volver a la atención normal en la prestación de cuidados. Objetivo: En el presente estudio, realizamos un análisis descriptivo retrospectivo del escenario epidemiológico de la sala del Grupo de Columna Vertebral del Hospital das Clínicas de la Facultad de Medicina de la Universidade de São Paulo (HC-FMUSP). Método: El análisis de los datos se realizó con acceso al prontuario médico de los pacientes. Resultados: En el período analizado, hubo 152 consultas en hospitalización, siendo la principal causa trauma espinal. Del total de casos, solo el 23,68% fueron programados de forma electiva que, a pesar de ser un número inferior al esperado, estuvo condicionado por las demandas de atención urgente canalizadas al servicio en cuestión. Conclusión: A pesar del aumento de asistencias en el período postpandemia, hay espacio para una mayor recuperación futura en el volumen de casos electivos. Nivel de Evidencia III; Estudio Retrospectivo de Serie de Casos. Introdución 2020 pandemia Covid19. Covid19 Covid 19. 19 Covid-19 2022 Brasil cuidados Objetivo estudio HCFMUSP. HCFMUSP HC FMUSP . (HC-FMUSP) Método pacientes Resultados analizado 15 hospitalización espinal 2368 23 68 23,68 esperado cuestión Conclusión postpandemia electivos III Casos 202 Covid1 1 Covid-1 (HC-FMUSP 236 2 6 23,6 20 Covid- 23,

RESUMO Introdução: Em março de 2020, a OMS decretou oficialmente que o mundo atravessava uma pandemia, a Covid-19. Em maio de 2022, no Brasil, decretou-se o fim das medidas de enfrentamento à pandemia. No ano de 2022, houve um movimento de retorno à normalidade assistencial na prestação de atendimentos. Objetivo: No presente estudo, realiza-se uma análise retrospectiva descritiva do cenário epidemiológico da enfermaria do Grupo de Coluna Vertebral do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP). Método: A análise dos dados foi efetuada a partir do levantamento de prontuários médicos. Resultados: No período analisado, houveram 152 atendimentos em regime de internação, com a principal causa sendo o traumatismo da coluna vertebral. De todos os casos, apenas 23,68% foram casos agendados em regime eletivo, o que apesar de ser um número abaixo do esperado, foi moldado pelas demandas dos atendimentos de urgência canalizados ao serviço em questão. Conclusão: Apesar do aumento de atendimentos no período pós pandemia, há espaço para maior retomada do volume de casos eletivos no futuro. Nível de Evidência III; Estudo Retrospectivo de Série de Casos. Introdução 2020 pandemia Covid19. Covid19 Covid 19. 19 Covid-19 2022 Brasil decretouse se Objetivo estudo realizase realiza HCFMUSP. HCFMUSP HC FMUSP . (HC-FMUSP) Método médicos Resultados analisado 15 internação vertebral 2368 23 68 23,68 eletivo esperado questão Conclusão futuro III Casos 202 Covid1 1 Covid-1 (HC-FMUSP 236 2 6 23,6 20 Covid- 23,

ABSTRACT Introduction: In March 2020, WHO officially decreed that the world was going through a pandemic, that of Covid-19. In May 2022, in Brazil, the end of measures to deal with the pandemic was decreed. In 2022, there was a movement to return to normal care in the provision of care. Objective: In the present study, we carried out a retrospective descriptive analysis of the epidemiological scenario of the ward of the Spine Group at the Hospital das Clínicas of the Faculty of Medicine of the Universidade de São Paulo (HC-FMUSP). Method: Data analysis was performed from information gathered in patients’ medical records. Results: In the analyzed period, there were 152 consultations in hospitalization, with the main cause being spinal trauma. Of all the cases, only 23.68% were scheduled on an elective basis, which despite being a lower than expected number, was shaped by the demands of urgent care channeled to the service in question. Conclusion: Despite a higher number of cases hospitalized in the post-pandemic period, there is still the expectancy of more elective cases to be treated in the future. Level of Evidence III; Retrospective Case Series Study. Introduction 2020 Covid19. Covid19 Covid 19. 19 Covid-19 2022 Brazil Objective study HCFMUSP. HCFMUSP HC FMUSP . (HC-FMUSP) Method patients records Results period 15 hospitalization trauma 2368 23 68 23.68 basis question Conclusion postpandemic post future III Study 202 Covid1 1 Covid-1 (HC-FMUSP 236 2 6 23.6 20 Covid- 23.

Resumo Entre os principais responsáveis pelas emissões de CO2 na camada de ozônio, a indústria da construção civil contribui com uma parcela significativa. Esta emissão é gerada em grande parte pela aplicação de sistemas de construção em concreto e suas variações. Portanto, é importante o uso de ferramentas que permitam o desenvolvimento de projetos que mitiguem os efeitos das emissões de gases nocivos para a atmosfera. Desse modo, este estudo aplicou um algoritmo de otimização chamado Firefly Algorithm (FA) para projetar vigas retangulares pré-fabricadas e protendidas com foco na redução da emissão de CO2 na fase de projeto estrutural. A Função Objetiva (FO) foi definida como o peso total de CO2 emitido em cada fase de construção (produção, transporte e montagem) e as restrições de projeto estrutural são baseadas nos critérios de projeto estabelecidos na ABNT NBR 6118. As variáveis do problema de otimização tratam de propriedades geométricas e condições mecânicas da viga, onde foram consideradas variáveis de projeto a altura da viga, espessura da viga, a proporção de altura que gera excentricidade de protensão, e a proporção da força de protensão. Foram analisadas dez vigas, com diferentes carregamentos, onde cada uma dessas vigas foi submetida ao processo de otimização trinta vezes. Para as condições propostas, as dez vigas apresentaram uma emissão de CO2 médio de 3282.59 kg, emissão de carbono máximo e mínimo de 3630.52 kg e 2910.67 kg, respectivamente. O estudo resultou em uma taxa de factibilidade superior à 90%, mostrando que a ferramenta de otimização foi eficiente na fase de projeto estrutural com foco na sustentabilidade. Em relação a emissão de carbono, é possível verificar uma relação entre o aumento da emissão e o carregamento visto que peças com maior inércia tendem a emitir uma maior quantidade de CO2. Ainda foi possível determinar uma regressão entre a emissão de carbono e o carregamento da viga.

Abstract Among the main contributors to CO2 emissions on the ozone layer, the construction industry contributes with a significant portion. This emission is generated largely by applying concrete construction systems and their variations. Therefore, it is important to use tools that allow the development of projects which mitigate the effects of harmful gas emissions into the atmosphere. Thus, this study applied an optimization algorithm called Firefly Algorithm (FA) to design precast and prestressed rectangular beams focusing on reducing CO2 emissions in the structural design phase. The Objective Function (OF) was defined as the total weight of CO2 emitted in each construction phase (production, transportation, and placement) and the structural design constraints are based on the design criteria established in ABNT NBR 6118. The problem optimization’s variables are geometric properties and mechanical beam's conditions, where the beam height, beam width, the proportion of height generates prestressing eccentricity, and the proportion of prestressing load were considered as design variables. Ten beams were analyzed, with different loadings, where each of these beams was submitted to the optimization process thirty times. For the proposed conditions, the ten beams had an average CO2 emission of 3282.59 kg, maximum and minimum carbon emission of 3630.52 kg and 2910.67 kg, respectively. The study resulted in a feasibility rate higher than 90%, showing that the optimization tool was efficient in the structural design phase focusing on sustainability. Concerning carbon emission, it is possible to verify a relationship between the increase of emission and the load since element with greater inertia tend to emit a greater amount of CO2. It was also possible to determine a regression between carbon emission and beam load.

RESUMO A vigilância da qualidade dos esgotos sanitários pode representar uma ferramenta complementar para monitoramento de doenças infecciosas e prevenção de surtos epidêmicos, especialmente quando a capacidade para testes clínicos é limitada. Dessa maneira, o presente estudo descreve o detalhamento técnico de um método de baixo custo para a concentração e extração de ácidos nucleicos de amostras de esgoto sanitário como etapa prévia para a detecção de vírus e outros agentes patogênicos. Para validar a metodologia proposta, após as etapas de concentração e extração, analisaram-se a presença do ácido ribonucleico do SARS-CoV-2 (COVID-19) nas amostras, por meio de reação em cadeia da polimerase em tempo real. O ácido ribonucleico do vírus foi detectado em 80% das amostras de esgoto sanitário analisadas, comprovando o êxito do procedimento metodológico adotado. A detecção precoce de um patógeno associado ao trabalho de equipes multidisciplinares possibilita a prática da vigilância epidemiológica, que auxilia na tomada de decisões na Saúde Única — união indissociável entre a saúde animal, humana e ambiental.

ABSTRACT Sewage quality surveillance can represent a complementary tool for monitoring infectious diseases and preventing epidemic outbreaks, especially when the capacity for clinical testing is limited. Thus, the present study describes the technical details of a low-cost method for concentrating and extracting nucleic acids from sewage samples, as a preliminary step for the detection of viruses and other pathogens. To validate the proposed methodology, after the concentration and extraction steps, the presence of the SARS coronavirus-2 (COVID-19) in the samples was analyzed using real-time polymerase chain reaction. The virus’ ribonucleic acid was detected in 80% of the sewage samples analyzed, proving the success of the methodological procedure adopted. The early detection of a pathogen associated with the work of multidisciplinary teams allows the practice of epidemiological surveillance, which assists in making decisions about One Health — an inseparable union between animal, human, and environmental health.

ABSTRACT Objective: To evaluate genotoxicity of zinc oxide, P. A. calcium hydroxide, mineral trioxide aggregate and an iodoform paste using comet assay on human lymphocytes. Material and Methods: Two positive controls were used: methyl-methanesulfonate for the P.A. calcium hydroxide and mineral trioxide aggregate; and doxorubicin for the iodoform paste and zinc oxide. There were also two negative controls: distilled water for the P.A. calcium hydroxide and mineral trioxide aggregate; and DMSO for the iodoform paste and zinc oxide. Comets were identified using fluorescence microscopy and 100 of them were counted on each of the three slides analyzed per drug test. A damage index was established, taking into consideration the score pattern that had previously been determined from the size and intensity of the comet tail. Analysis of variance, followed by Tukey’s test, was used to compare the means of the DNA damage indices. Results: The DNA damage index observed for mineral trioxide aggregate (7.08 to 8.58) and P.A. calcium hydroxide (6.50 to 8.33), which were similar to negative control index. On the other hand, damage index for zinc oxide (104.7 to 218.50) and iodoform paste (115.7 to 210.7) were similar to positive control index. Conclusion: Iodoform paste and zinc oxide showed genotoxicity at all concentrations used.

RESUMO O objetivo desse estudo foi analisar a associação entre as características antropométricas, ocupacionais, nível de atividade física e à ideação suicida em policiais militares de Aracaju e Região Metropolitana, Brasil. Participaram do estudo 254 policiais militares ativos do sexo masculino e feminino, com idade entre 21 e 55 anos. Os dados foram coletados através do Formulários Google, contendo questões sobre características sociodemográficas, antropométricas, ocupacionais e comportamentos de risco. Foi realizada estatística descritiva com média, desvio padrão, frequência absoluta, relativa e para os casos específicos, análise de regressão logística binária. Policiais militares com menos tempo de serviço tinham quatro vezes mais chances de apresentar tristeza profunda nos últimos 12 meses (OR = 0,22; 95% IC 0,09-0,51), e policiais mais velhos três vezes mais chances (OR = 3,12; 95% IC 1,64-7.97). Policiais que trabalhavam em turnos do dia alternados, apresentaram quatro vezes mais chances de ter planejado suicídio nos últimos 12 meses (OR = 4,67; 95% IC 1,08-20,16), e policiais com menos tempo de serviço apresentaram sete vezes mais chances (OR = 0,13; 95% IC 0,26-0,64). É observado que as características laborais estão associadas a ideação suicida. Também é percebido que à atividade física é um fator de proteção contra tristeza profunda.

ABSTRACT This study aimed to analyse the association between anthropometric characteristics, occupational status, physical activity level, and suicidal ideation among military police in Aracaju and the Metropolitan Region, Brazil. 254 active male and female military policemen, aged between 21 and 55 years, participated in the study. 254 military police participated in the study. Data were collected through Google Forms, containing questions about sociodemographic, anthropometric, occupational characteristics, and risk behaviours. Military officers with less service were four times more likely to experience profound sadness in the past 12 months (OR = 0.22; 95% CI 0.09-0.51), and older officers three times more likely (OR = 3.12; 95% CI 1.64-7.97). Police officers who worked alternate day shifts were four times more likely to have planned suicide in the past 12 months (OR = 4.67; 95% CI 1.08-20.16), and police officers with less time on duty had seven times more chances (OR = 0.13; 95% CI 0.26-0.64). It is observed that labour characteristics are associated with suicidal ideation. It is also perceived that physical activity is a protective factor against profound sadness.

RESUMO Avaliar a relação do nível de atividade física com o perfil antropométrico, percepção de qualidade de vida e saúde mental em policiais militares do Estado de Sergipe (PM/SE). Estudo transversal que contou com 30 policiais militares do sexo masculino, com idade entre 28 a 40 anos. Utilizaram o pedômetro durante quatro dias, posteriormente responderam questionários sobre: Dados Demográficos, Antropométricos e Ocupacionais; IPAQ versão curta; WHOQOL; Escala de Ansiedade, Depressão e Estresse. Apresentaram, prevalência de policiais ativos (70%) e não apresentam sintomas para problemas que afetem a saúde mental. 66,67% relataram boa percepção e qualidade de vida e 70% estavam satisfeitos com sua saúde. Houve correlação do nível de atividade física com o estresse no dia de serviço e no primeiro dia de folga com indicadores de qualidade de vida. Houve correlação do nível de atividade do primeiro dia de folga com os domínios Físico (R=0,411; p<0,05) e do Meio Ambiente (R=0,511; p<0,05). Apresentou-se bons níveis de saúde mental. Quanto ao nível de atividade física, percebeu-se relação positiva do dia de serviço com a variável estresse. Houve relações positivas do nível de atividade do primeiro dia de folga com os domínios Físico e Meio Ambiente a respeito da Qualidade de Vida.

ABSTRACT This study aimed to evaluate the relationship between the level of physical activity and the anthropometric profile, perception of quality of life, and mental health in military police officers from the State of Sergipe (PM / SE). This cross-sectional study involved 30 male military police officers, aged 28 to 40 years. They used the pedometer for four days, then answered questionnaires about: Demographic, Anthropometric, and Occupational Data; IPAQ short version; WHOQOL; Anxiety, Depression and Stress Scale. They had a prevalence of active police (70%) and had no symptoms for problems that affect mental health. 66.67% reported good perception and quality of life, and 70% were satisfied with their health. There was a correlation between the level of physical activity and stress on the day of service and the first day off with quality-of-life indicators. There was a correlation between the activity level of the first day off with the Physical (R = 0.411; p <0.05) and the Environment (R = 0.511; p <0.05) domains. Good levels of mental health were presented. As for the level of physical activity, there was a positive relationship between the day of service and the stress variable. There were positive relationships between the activity level of the first day off and the Physical and Environment domains regarding Quality of Life.

A novel method for the synthesis of nonsymmetrical 3,3’-(aryl/alkyl-methylene)bis-2-hydroxy-1,4-naphthoquinones was developed by using the Mannich adduct of naphthoquinone and the reaction with another moiety of 2-hydroxy-1,4-naphthoquinone. This novel method produces for the first time nonsymmetrical 3,3’-(aryl/alkyl-methylene)bis-2-hydroxy-1,4-naphthoquinones. In a preliminary study, these compounds (15c, 15f and 15h) were evaluated regarding their effect over the viability of PC3 metastatic prostate cancer cell using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays at 100 µM. Three of these compounds presented relevant cytotoxic effects at 72 h posttreatment.

Abstract Background: Hospital accreditation has as goal the standardization of patient care, aiming quality improvement. On 2015, a cardiology reference hospital was evaluated and got level 3 from ONA in care given to Acute Coronary Syndrome (ACS) patients. Objetive: To compare length of stay (LOS) at Coronary Care Unit (CCU) and the total LOS at the hospital of ACS patients before and after ONA 3 accreditation. Other clinical outcomes were also analyzed. Methods: Systematic and prospective registry of admitted ACS patients at CCU, whose population was divided into pre-accreditation (period 1) and post-accreditation (period 2). Descriptive analysis was performed. For statistical analysis the Mann-Whitney test, chi-squared, Fisher’s exact test and Multiple Linear Regression were performed. P value was considered statistically significant when < 0,05. Results: 372 patients were admitted with ACS, 186 in period 1, of which 47 (25,3%) with ST segment Elevation Myocardial Infarction (STEMI), and 186 in period 2, of which 70 (37,6%) with STEMI. The mean age was 65,9 years (± 12,2). About the CCU LOS, there was a reduction from 3 (IQR: 2-4) to 2,5 days (IQR: 2-4; p value = 0,088). Regarding the hospital LOS, there was also a reduction from 8 (IQR: 5-12,25) to 6 days (IQR:4-11; p value = 0,004). Analyzing the type of ACS, there was a significant reduction only at the hospital LOS in non-STEMI patients: 8 to 6 days (p value = 0,001). Other hospitalization length of stay and clinical outcomes did not present a significant reduction in the comparison. Conclusion: After the ONA 3 accreditation, there was a reduction of hospital LOS. There were no significant differences in the other outcomes analyzed.

RESUMO: A aplicação de herbicidas dessecantes na cultura do feijoeiro é fundamental na produção de sementes de qualidade porque antecipa a época de colheita, o que possibilita a obtenção de sementes no período de maturação fisiológica, quando se encontram com máximo acúmulo de matéria seca, elevados níveis de vigor e alta porcentagem de germinação. Todavia, são escassas as informações acerca da época ideal de aplicação desses produtos na obtenção de sementes de feijão de alta qualidade fisiológica. Por essa razão, objetivou-se avaliar a qualidade fisiológica de sementes de feijão após aplicações de herbicidas dessecantes em diferentes épocas na pré-colheita. O delineamento experimental utilizado foi o de blocos casualizados dispostos em esquema fatorial 2x3+1, com quatro repetições. A aplicação dos herbicidas dessecantes paraquat (400g ha-1) e paraquat + diuron (200+400g ha-1) foi realizada em três estádios fenológicos (R8, R8/R9 e R9), mais uma testemunha (sem aplicação do herbicida). Avaliou-se a produtividade (Kg ha-1), a massa de mil sementes (g), a germinação (%) e o vigor das sementes por meio dos testes de envelhecimento acelerado, condutividade elétrica e comprimento da raiz primária. A aplicação da molécula de paraquat no estádio R8 e da mistura paraquat + diuron no estágio R8/R9 reduziu a viabilidade e o vigor das sementes de feijão, além disso comprometeu a produtividade. Aplicações dos herbicidas paraquat nos estádios R8/R9 e R9 ou da mistura (paraquat + diuron) no estádio R9 preservaram a qualidade fisiológica das sementes, sem, entretanto, afetar a produtividade.

ABSTRACT: The application of desiccant herbicides in the bean crop is fundamental in the production of quality seeds, since it anticipates the harvesting season, which makes it possible to obtain seeds in the period of physiological maturation, when they are reported with maximum accumulation of dry matter, high vigor levels and germination percentage. However, there is little information about the ideal application time of these products to obtain beans of high physiological quality. Therefore, the objective of this study was to evaluate the physiological quality of bean seeds after application of desiccant herbicides at different times in preharvest. The experimental design was a randomized complete block design in a 2x3+1 factorial scheme, with four replications. Desiccant herbicides paraquat (400g ha-1) and paraquat + diuron (200 + 400g ha-1) were applied in three phenological stages (R8, R8/R9 and R9), plus one control (without herbicide application). Yield (Kg ha-1), mass of one thousand seeds (g), germination (%) and seed vigor were evaluated through tests of accelerated aging, electrical conductivity and primary root length. Application of paraquat molecule at the R8 stage and the paraquat + diuron mixture at the R8/R9 stage reduced the viability and vigor of the bean seeds, and compromised yield. Applications of the paraquat herbicide at the R8/R9 and R9 stages or of the mixture (paraquat + diuron) at the R9 stage preserved the physiological quality of the seeds without;however, affecting yield.

ABSTRACT Objective: to analyze the discourse of women on the interface between marital violence and alcohol use by the partner. Method: qualitative exploratory research, based on the methodological reference of oral history. We interviewed 19 women with a history of marital violence and involvement with drugs. The data were analyzed through discourse of the collective subject. Results: the participants’ discourse points to consumption of alcohol by partners as a potentiating element of violent episodes, also experienced by their parents, signaling to its transgenerational character; it also calls attention to the danger of marital violence resulting from men’s reactions to having their alcohol consumption questioned by their partners. Final considerations: the study identifies alcohol as a precipitating and/or potentiating factor of conjugal violence, as well as the intergenerational character of violence based on male domination and intolerance.

RESUMEN Objetivo: analizar el discurso de las mujeres sobre la interfaz entre la violencia conyugal y el uso de alcohol por el compañero. Método: investigación exploratoria, cualitativa, basada en el referencial metodológico de la historia oral. Se entrevistaron a 19 mujeres con antecedentes de violencia conyugal e implicación con drogas. Los datos fueron analizados a través del discurso del sujeto colectivo. Resultados: el discurso de las participantes apunta el consumo del alcohol por el compañero como elemento impulsor de los episodios violentos, evento también experimentado por los padres, señalando para su carácter transgeneracional; advierte también a la violencia conyugal derivada de la reacción del hombre al ser cuestionado por la compañera en cuanto al consumo del alcohol. Consideraciones finales: el estudio identifica el alcohol como factor precipitador y/o impulsor de la violencia conyugal, así como el carácter intergeneracional de la violencia basada en la concepción de dominación e intolerancia masculina.

RESUMO Objetivo: analisar o discurso de mulheres sobre a interface entre violência conjugal e uso de álcool pelo companheiro. Método: pesquisa exploratória, qualitativa, fundamentada no referencial metodológico da história oral. Foram entrevistadas 19 mulheres com história de violência conjugal e envolvimento com drogas. Os dados foram analisados através do discurso do sujeito coletivo. Resultados: o discurso das participantes aponta o consumo do álcool pelo companheiro como elemento potencializador dos episódios violentos, evento também experienciado pelos pais, sinalizando para seu caráter transgeracional; alerta ainda para a violência conjugal decorrente da reação do homem ao ser questionado pela companheira quanto ao consumo do álcool. Considerações finais: o estudo identifica o álcool como fator precipitador e/ou potencializador da violência conjugal, bem como o caráter intergeracional da violência alicerçada na concepção de dominação e intolerância masculina.