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Resumo Este artigo apresenta os impactos da pandemia nos sistemas de saúde e as repercussões nas condições de trabalho e saúde mental dos profissionais de saúde e trabalhadores invisíveis da saúde no contexto da COVID-19. Apresenta a mortalidade entre os profissionais da saúde destacando a necessidade de melhores condições de trabalho e de segurança para os trabalhadores da saúde e melhora da gestão pública. Enfatiza as recomendações da OMS/OPAS, a necessidade de vacinação equânime, incluindo os países mais pobres e as populações mais vulneráveis. Relata os impactos da interrupção dos serviços essenciais em saúde, como para as doenças crônicas e infecciosas, e os prejuízos causados pela disseminação de informações falsas pela rede social, e lembra da necessidade de veiculação de informações corretas e seguras na saúde. COVID19. COVID19 COVID 19. 19 COVID-19 pública OMSOPAS OMS OPAS OMS/OPAS equânime vulneráveis infecciosas social COVID1 1 COVID-1 COVID-

Abstract This article discusses the impacts of the COVID-19 pandemic on health systems and its effects on the working conditions and mental health of health professionals and invisible health workers. It presents data on deaths among health professionals, highlighting the need for better and safer working conditions and improvements in public management. We emphasize WHO/PAHO recommendations and the need for equitable vaccine distribution, including poor countries and vulnerable populations. We also highlight the impacts of interrupting essential health services, such as the treatment of chronic conditions and infectious disease prevention, and the damage caused by the dissemination of fake news, stressing the need to improve access to correct and safe health information. COVID19 COVID 19 COVID-1 workers management WHOPAHO WHO PAHO distribution populations services prevention news information COVID1 1 COVID-

https://doi.org/10.1590/1413-812320232810.10102023

COVID-19 e os sistemas de saúde do Brasil e do mundo: repercussões das condições de trabalho e de saúde dos profissionais de saúde
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Machado, Antônio Vieira

; Ferreira, Wagner Eduardo

; Vitória, Marco Antônio de Ávila

; Magalhães Júnior, Helvécio Miranda

; Jardim, Letícia Lemos

; Menezes, Marco Antônio Carneiro

; Santos, Renato Penha de Oliveira

; Vargas, Filipe Leonel

; Pereira, Everson Justino

Ciência & Saúde Coletiva

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oct 2023, Volume 28 N. 10 Pages 2965 - 2978

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-812320232810.10102023

[SciELO Preprints] - Passifloraceae s.s. from the São Luís Island, Maranhão State, Brazil
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Garcia, Amanda Letícia Silva, Eduardo Oliveira Ferreira, Alessandro Wagner Coelho Marinho, Lucas Cardoso

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Publication date: 2023-05-16

Abstract: En Pt

The São Luís Island, Maranhão State, is an ecotonal region, a mix of humid forest, cocais forest, dune vegetation, restingas and mangroves. Unlike the interior of the State, their coastal areas have a gap in knowledge of the Passifloraceae. Here, through field expeditions and herbaria visit, we provide taxonomic treatment, identification key and comments on the Passifloraceae of the São Luís Island. Ten species were recorded: Passiflora auriculata Kunth, P. edulis Sims, P. foetida L., P. glandulosa Cav., P. laurifolia L., P. misera Kunth, P. nitida Kunth, P. picturata Ker Gawl., P. subrotunda Mast., and P. vespertilio L. Passiflora picturata and P. misera were recorded for the first time on São Luís Island.

A Ilha de São Luís, Estado do Maranhão, configura-se como uma região ecotonal, um misto de floresta úmida, mata-de-cocais, vegetação de dunas, restingas e manguezais. Diferentemente do interior do Estado do Maranhão, suas zonas costeiras possuem uma lacuna sobre o conhecimento da família Passifloraceae. Aqui, por meio de expedições de campo e consulta a herbários, nós fornecemos o tratamento taxonômico, chave de identificação e comentários sobre as Passifloraceae da Ilha de São Luís. Foram registradas dez espécies: Passiflora auriculata Kunth, P. edulis Sims, P. foetida L., P. glandulosa Cav., P. laurifolia L., P. misera Kunth, P. nitida Kunth, P. picturata Ker Gawl., P. subrotunda Mast. e P. vespertilio L. As espécies P. picturata e P. misera foram registradas pela primeira vez na Ilha de São Luís.

https://doi.org/10.1590/2236-8906-56/2022

Protagonismo juvenil no ensino médio: reflexões acerca da elaboração e implementação dos jogos interclasses médio
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Nazario, Murilo Eduardo dos Santos

; Santos, Wagner dos

; Ferreira Neto, Amarílio

Pro-Posições

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2023, Volume 34 elocation e20210132

Abstract: Es Pt En | Text: Es Pt En | PDF: Es | PDF: Pt | PDF: En

Resumen La pregunta que orienta este estudio es: ¿cómo se pueden constituir los juegos interclase como contenido didáctico desde la perspectiva del protagonismo juvenil en la educación física del bachillerato? El objetivo es discutir y analizar las posibilidades y limitaciones que implican los juegos interclase como contenido didáctico dentro de una escuela secundaria. Así, se llevó a cabo un estudio de caso etnográfico de la vida escolar cotidiana. Para ello, se organizaron juegos interclase en una escuela secundaria, basados ??en las estructuras del protagonismo juvenil. Los resultados indican que el saber / hacer inherente al deporte puede asumir no solo un lugar de conocimiento para ser aplicado en un entorno competitivo, sino como estructuras que permitan comprender el lugar sociocultural del deporte. cómo bachillerato secundaria Así cotidiana ello competitivo

Resumo A questão que orienta este estudo é: de que modo os jogos interclasses podem constituir-se como conteúdo de ensino na perspectiva do protagonismo juvenil na educação física do ensino médio? Objetiva-se discutir e analisar as possibilidades e limitações dos jogos interclasses como conteúdo de ensino em uma escola de ensino médio. Sendo assim, realizou-se um estudo de caso etnográfico do cotidiano escolar. Para tanto, organizou-se os jogos interclasses, em uma escola de ensino médio, a partir das estruturas do protagonismo juvenil. Os resultados sinalizam que os saberes/fazeres inerentes aos esportes podem assumir não somente um lugar de conhecimentos a serem aplicados em âmbito competitivo, mas sim como estruturas que permitem compreender o lugar sociocultural do esporte. é constituirse constituir se médio Objetivase Objetiva assim realizouse realizou escolar tanto organizouse organizou saberesfazeres saberes fazeres competitivo esporte

Abstract The question that guides this study is: how can interclass games be constituted as teaching content from the perspective of youth protagonist in high school physical education? The objective is to discuss and analyze the possibilities and limitations that involve interclass games as teaching content within a high school. Thus, an ethnographic case study of everyday school life was carried out. For this purpose, interclass games were organized in a high school, based on the structures of youth protagonist. The results indicate that the knowledge/doing inherent to sports can assume not only a place of knowledge to be applied in a competitive environment, but as structures that allow understanding the sociocultural place of sport. education Thus out purpose knowledgedoing doing environment sport

https://doi.org/10.1590/1980-6248-2021-0132

Passifloraceae s.s. da Ilha de São Luís, Estado do Maranhão, Brasil ss s s.s Luís Maranhão
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Garcia, Amanda Letícia

; Silva, Eduardo Oliveira

; Ferreira, Alessandro Wagner Coelho

; Marinho, Lucas Cardoso

Hoehnea

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2023, Volume 50 elocation e562022

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO A Ilha de São Luís, Estado do Maranhão, configura-se como uma região ecotonal, um misto de floresta úmida, mata-de-cocais, vegetação de dunas, restingas e manguezais. Diferentemente do interior do Estado do Maranhão, suas zonas costeiras possuem uma lacuna sobre o conhecimento da família Passifloraceae. Aqui, por meio de expedições de campo e consulta a herbários, nós fornecemos o tratamento taxonômico, chave de identificação e comentários sobre as Passifloraceae da Ilha de São Luís. Foram registradas dez espécies: Passiflora auriculata Kunth, P. edulis Sims, P. foetida L., P. glandulosa Cav., P. laurifolia L., P. misera Kunth, P. nitida Kunth, P. picturata Ker Gawl., P. subrotunda Mast. e P. vespertilio L. As espécies P. picturata e P. misera foram registradas pela primeira vez na Ilha de São Luís. Luís Maranhão configurase configura se ecotonal úmida matadecocais, matadecocais mata cocais, cocais mata-de-cocais dunas manguezais Aqui herbários taxonômico Kunth P Sims L Cav Cav. Gawl Gawl. Mast

ABSTRACT The São Luís Island, Maranhão State, is an ecotonal region, a mix of humid forest, cocais forest, dune vegetation, restingas and mangroves. Unlike the interior of the State, their coastal areas have a gap in knowledge of the Passifloraceae. Here, through field expeditions and herbaria visit, we provide a taxonomic treatment, identification key and comments on the Passifloraceae of the São Luís Island. Ten species were recorded: Passiflora auriculata Kunth, P. edulis Sims, P. foetida L., P. glandulosa Cav., P. laurifolia L., P. misera Kunth, P. nitida Kunth, P. picturata Ker Gawl., P. subrotunda Mast., and P. vespertilio L. Passiflora picturata and P. misera were recorded for the first time on São Luís Island. Island State region forest vegetation mangroves Here visit treatment Kunth P Sims L Cav Cav. Gawl Gawl. Mast Mast.

https://doi.org/10.1590/2236-8906e562022

Efficiency of inoculation methods for genotypes selection in corn ear rot disease studies
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da Cruz Araújo, Sabrina Helena

; Rosa Júnior, Oelton Ferreira

; Viteri, Luis Oswaldo

; Aguiar, Raimundo Wagner

; de Oliveira, Eugênio Eduardo

; Rodrigues dos Santos, Gil

Revista de Ciencias Agrícolas

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dec 2022, Volume 39 N. 2 Pages 160 - 173

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT The identification of resistance of plants to pathogens is crucial for the development of hybrids by breeding programs. To achieve that, it is of great relevance to establish effective inoculation methods for characterizing genotypes with adequate plant resistance levels. Several inoculation methods have been investigated in the search for resistance to corn ear rot disease. However, studies evaluating different corn genotypes cultivated under Neotropical field conditions remain unexplored. Here, we compared three inoculation methods (i.e., aspersion, injectable, and natural) of Fusarium verticillioides in corn ears, and evaluated disease severity and grain yield of 10 corn genotypes. The experiments were conducted in two consecutive experimental corn crop (i.e., 2015 and 2016) seasons located in cities with different environmental temperatures and belonging to different Brazilian states (i.e., Gurupi - Tocantins State, Itumbiara - Goiás State, Planaltina - Brazilian Federal District, and Toledo - Paraná State). We evaluated the mass of 1000 grains and the severity of the disease. Regarding the disease severity, our results showed that the artificial inoculation was more efficient in the regions of Planaltina and Toledo, not affecting grains’ mass in these localities. The severity of disease on the conditions of Toledo was similar for the ten genotypes. However, it was possible to identify two contrasting genotypes since P4285H (low severity) and 32R48YH (medium severity) exhibited significantly more disease symptoms in all other regions. Although the differences regarding the efficiency of inoculation methods are more evident in regions with milder temperatures, the results showed that the characterization of genotypes susceptible to the pathogen is more efficient in regions with higher temperatures.

RESUMEN La identificación de la resistencia de las plantas a patógenos es crucial para el desarrollo de híbridos mediante programas de mejoramiento. Para lograr este objetivo, es de gran importancia establecer métodos de inoculación efectivos para caracterizar genotipos con niveles de resistencia adecuados. En la búsqueda de resistencia a pudrición de la mazorca del maíz, varios métodos de inoculación han sido investigados. Sin embargo, estudios que evalúan diferentes genotipos de maíz cultivados en condiciones de campo neotropicales siguen sin explorarse. Aquí, comparamos tres métodos de inoculación (i.e. aspersión, inyectable y natural) de Fusarium verticillioides en mazorcas de maíz y evaluamos la gravedad de la enfermedad y el rendimiento del grano de 10 genotipos de maíz. Los experimentos fueron conduzidos en dos cultivos experimentales de maíz consecutivos (cosecha 2015/2016), ubicados en ciudades con diferentes temperaturas ambientales y pertenecientes a diferentes estados brasileños (i.e. Gurupi - Estado de Tocantins, Itumbiara - Estado de Goiás, Planaltina - Distrito Federal de Brasil y Toledo - Estado de Paraná). Se evaluó la masa de 1000 granos y la severidad de la enfermedad. En cuanto a la severidad de la enfermedad nuestros resultados mostraron que la inoculación artificial fue más eficiente en las regiones de Planaltina y Toledo, sin afectar la masa de granos en estas localidades. La severidad de la enfermedad en las condiciones de Toledo fue similar para los diez genotipos. Sin embargo, fue posible identificar dos genotipos contrastantes, ya que P4285H (severidad baja) y 32R48YH (severidad media) exhibieron significativamente más síntomas de la enfermedad en todas las demás regiones. Si bien las diferencias en cuanto a la eficiencia de los métodos de inoculación son más evidentes en la región con temperaturas más suaves, los resultados mostraron que la caracterización de genotipos susceptibles al patógeno es más marcante en las regiones con temperaturas más altas.

https://doi.org/10.22267/rcia.223902.191

[SciELO Preprints] - SUBJECTS, KNOWLEDGE AND DIDACTIC-PEDAGOGIC PRACTICES IN PHYSICAL EDUCATION IN/WITH/THE DAILY OF HIGH SCHOOL
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Nazario, Murilo Eduardo Santos, Wagner dos Ferreira Neto, Amarilio

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Publication date: 2022-08-11

Abstract: En Es Pt

This study is organized around the following question: what are the possible pedagogical didactic textures that can be undertaken in physical education in/with/with the daily life of high school, from (re)appropriation of curricular structures? It aims to analyze how the articulation between curricular signs can materialize as didactic-pedagogical actions in the daily life of high school. In order to do so, an ethnographic case study of daily school life was carried out with the principles of existential action research. In other words, the context of tensions, changes and reorganizations in which Brazilian secondary education is presented and its impacts on Physical Education constitute a fertile field for this type of methodological option. From this perspective, it became part of the daily life of a full-time school in the state network of Capixaba, founded in 1977. In this way, during approximately 700 Physical Education classes, which involved direct action with a teacher of the curricular component, ten classes of 1st to 3rd year and about 400 students, we sought to give visibility to the knowledge/doings mobilized in the spaces/times of this daily life. The results indicate educational actions in Physical Education that respect the particularities of daily school life. Therefore, what is being proposed represents a response to general events arising from national educational policies, but also represents responses to the problems and dilemmas typical of the daily life of the researched school.

Este estudio se organiza en torno a la siguiente pregunta: ¿cuáles son las posibles texturas didácticas pedagógicas que se pueden emprender en la educación física en/con/con el cotidiano de la escuela secundaria, a partir de la (re)apropiación de las estructuras curriculares? Tiene como objetivo analizar cómo la articulación entre signos curriculares puede materializarse como acciones didáctico-pedagógicas en el cotidiano de la escuela secundaria. Para ello, se realizó un estudio de caso etnográfico de la cotidianidad escolar con los principios de la investigación acción existencial. En otras palabras, el contexto de tensiones, cambios y reorganizaciones en que se presenta la educación secundaria brasileña y sus impactos en la Educación Física constituyen un campo fértil para este tipo de opción metodológica. Desde esa perspectiva, pasó a formar parte del cotidiano de una escuela de tiempo completo de la red estatal de Capixaba, fundada en 1977. De esta forma, durante aproximadamente 700 clases de Educación Física, que implicó la acción directa con un docente del componente curricular , diez clases de 1° a 3° año y cerca de 400 alumnos, buscamos dar visibilidad a los saberes/haceres movilizados en los espacios/tiempos de esta cotidianidad. Los resultados indican acciones educativas en Educación Física que respetan las particularidades del cotidiano escolar. Por tanto, lo que se propone representa una respuesta a los acontecimientos generales derivados de las políticas educativas nacionales, pero también representa respuestas a los problemas y dilemas inherentes al cotidiano de la escuela investigada

Este estudo organiza-se em torno da seguinte questão: quais as tessituras didático pedagógicas possíveis de serem empreendidas em educação física no/com/o cotidiano do ensino médio, a partir de (re) apropriações sobre as estruturas curriculares? Objetiva analisar como a articulação entres signos curriculares podem materializar-se como ações didático pedagógicas no cotidiano do ensino médio. Para tanto, realizou-se um estudo de caso etnográfico do cotidiano escolar com princípios da pesquisa ação existencial. Em outras palavras, o contexto de tensões, mudanças e reorganizações no qual o ensino médio brasileiro se apresenta e seus impactos na Educação Física constituem-se como campo fértil para esse tipo de opção metodológica. Nessa perspectiva, passou-se a integrar o cotidiano de uma escola de tempo integral da rede estadual Capixaba, fundada em 1977. Desse modo, durante aproximadamente 700 aulas de Educação Física, que envolveram ação direta com uma professora do componente curricular, dez turmas de 1º ao 3º ano e cerca de 400 alunos, buscou-se dar visibilidade aos saberes/fazeres mobilizados nos espaços/tempos desse cotidiano. Os resultados sinalizam ações educacionais em Educação Física que respeitem as particularidades próprias dos cotidianos escolares praticados. Sendo assim, o que está sendo proposto representa uma resposta aos acontecimentos gerais advindos das políticas educacionais nacionais, mas representam também respostas aos problemas e dilemas próprios do cotidiano da escola pesquisada.

https://doi.org/10.1590/SciELOPreprints.4566

Effect of the COVID-19 pandemic on patients with inherited neuromuscular disorders
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Moreno, Cristiane Araujo Martins

; Camelo, Clara Gontijo

; Sampaio, Pedro Henrique Marte de Arruda

; Fonseca, Alulin Tácio Quadros Santos Monteiro

; Estephan, Eduardo de Paula

; Silva, André Macedo Serafim

; Pirola, Renann Nunes

; Silva, Luiz Henrique Libardi

; Lima, Karlla Danielle Ferreira

; Albuquerque, Marco Antônio Veloso de

; Camelo Filho, Antonio Edvan

; Marques, Marcos Vinícius Oliveira

; Yanagiura, Mario Teruo

; Cavalcante, Wagner Cid Palmeira

; Matsui Junior, Ciro

; Isihi, Lucas Michielon de Augusto

; Mendonça, Rodrigo Holanda

; Pouza, Ana Flávia Pincerno

; Carvalho, Mary Souza de

; Reed, Umbertina Conti

; Zanoteli, Edmar

Arquivos de Neuro-Psiquiatria

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jun 2022, Volume 80 N. 6 Pages 563 - 569

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Antecedentes: A Pandemia por COVID-19 tem trazido desafios subtanciais para a prática clínica no tratamento das doenças neuromusculares hereditárias (DNMh). A infecção não tem sido a única preocupação para os pacientes. O distanciamento social tem comprometido a assistência multidisciplinar, atividade física e tem trazido problemas mentais em decorrência do próprio isolamento. Nós apresentamos aqui um seguimento de 363 pacientes com DNMh de um centro terciário Brasileiro durante o pico da Pandemia de Covid-19. Objetivos: Mostrar a frequência e gravidade da infecção por Sars-Cov-2 em pacientes com DNMh e demonstrar os efeitos da pandemia nos hábitos de vida, na progressão da doença e no cuidado multidisciplinary. Métodos Trezentos e sessenta e três pacientes (58% homens and 42% mulheres) foram acompanhados por 3 meses através de 3 teleconsultas durante o pico da Pandemia de Covid-19 no Brasil. Resultados Houve um decréscimo no número de pacientes que faziam terapia física, respiratória e fonoaudiológica. Em muitos pacientes, o apetite (33%) e hábitos do sono (25%) se alteraram. Exercícios físicos e terapias foram interrompidas pela maioria dos pacientes. Physical exercises and therapies were interrupted for most of the patients. Eles relataram piora ou aparecimento de fadiga (17%), dor (17%), retrações (14%), e escoliose (7%). Irritabilidade, mudanças no sono, peso e apetite, sendo principalmente diminuição do apetite e peso foram mais frequentemente encontrados em pacientes que apresentaram piora clinica da doença. Houve uma baixa taxa de contaminação por Covid-19 (0.8%), e todos os pacientes infectado apresentaram quadro clinico leve. Conclusão O isolamento por si só se mostrou protetor na perspectiva de infecção por Covid-19, mas pode desencadear um cenário complexo com mudanças nos hábitos de vida e curso desfavorável da doença de base.

ABSTRACT Background The COVID-19 pandemic has brought substantial challenges for current practices in treating hereditary neuromuscular disorders (hNMDs). However, this infection has not been the only concern for these patients. Social distancing has compromised multidisciplinary assistance and physical activity, and has brought about several mental health issues. We presented a follow-up on 363 patients with hNMDs at a Brazilian tertiary center during the peak of the COVID-19 pandemic. Objective We aimed to show the frequency and severity of SARS-CoV-2 infection among hNMD patients and to demonstrate the effects of the pandemic on life habits, disease progression and multidisciplinary supportive care status. Methods Three hundred and sixty-three patients (58% male and 42% female) were followed for three months through three teleconsultations during the peak of the COVID-19 pandemic in Brazil. Results There were decreases in the numbers of patients who underwent physical, respiratory and speech therapies. For several patients, their appetite (33%) and sleep habits (25%) changed. Physical exercises and therapies were interrupted for most of the patients. They reported new onset/worsening of fatigue (17%), pain (17%), contractions (14%) and scoliosis (7%). Irritability and sleep, weight and appetite changes, and especially diminished appetite and weight loss, were more frequent in the group that reported disease worsening. There was a low COVID-19 contamination rate (0.8%), and all infected patients had a mild presentation. Conclusion The isolation by itself was protective from a COVID-19 infection perspective. However, this isolation might also trigger a complex scenario with life habit changes that are associated with an unfavorable course for the NMD.

https://doi.org/10.1590/0004-282x-anp-2021-0166

Synopsis of Orchidaceae from Fazenda Sete Irmãos: a fragment of Amazon Forest in northwestern Maranhão, Brazil
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Silva, Maycon Jordan Costa da

; Pansarin, Emerson Ricardo

; Pessoa, Edlley

; Silva, Eduardo Oliveira

; Albuquerque, Patrícia Maia Correia de

; Oliveira, Miguel Sena de

; Silva Junior, Wagner Ribeiro da

; Santos, Kedma Nunes

; Lima, Jonaina Ferreira

; Ferreira, Alessandro Wagner Coelho

Rodriguésia

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2022, Volume 73 elocation e02172020

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Este estudo apresenta um inventário das Orchidaceae em uma das áreas mais ameaçadas da Amazônia Brasileira, localizada na porção mais oriental do Centro de Endemismo Belém. São registradas 51 espécies distribuídas em 24 gêneros. Epífitas representam 86% das espécies, as demais são terrícolas (6%), hemiepífitas (6%) ou micoheterotrófica (2%). Os gêneros mais representativos foram Epidendrum (6 spp.) e Maxillaria (5 spp.). Este estudo registra pela primeira vez cinco gêneros (Coryanthes, Sarcoglottis, Stelis, Trichosalpinx e Wullschlaegelia) e dez espécies para a flora do Maranhão, dos quais, quatro também são novos registros para a Região Nordeste do Brasil. Uma chave de identificação, pranchas fotográficas dos novos registros e comentários taxonômicos, ecológicos e de distribuição geográfica são apresentados. Os dados evidenciam a importância dos fragmentos de Floresta Amazônica do Maranhão para a proteção das Orchidaceae, constantemente ameaçadas pelo desmatamento no Centro de Endemismo Belém.

Abstract This study provides an inventory of the Orchidaceae in one of the most threatened areas of the Brazilian Amazon, situated in the eastern portion of the Belém Endemism Center. A total of 51 species, distributed in 24 genera, are recorded. Epiphytes represent 86% of the species, the remaining are terricolous (6%), hemiepiphytic (6%) or myco-heterotrophic (2%). The most representative genera were Epidendrum (6 spp.) and Maxillaria (5 spp.). This study cites for the first time five genera (Coryanthes, Sarcoglottis, Stelis, Trichosalpinx and Wullschlaegelia) and ten species for the flora of Maranhão, of which four are new records to the Brazilian Northeast. An identification key, photographs of the new records, taxonomic and ecological comments, as well as geographic distribution are provided. The data reinforce the importance of the forest fragments of the Amazon Forest in Maranhão for the conservation of Orchidaceae which is constantly threatened by deforestation in the Belém Endemism Center.

https://doi.org/10.1590/2175-7860202273044

10.

Práticas de ressuscitação volêmica em unidades de terapia intensiva brasileiras: uma análise secundária do estudo Fluid-TRIPS
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Freitas, Flavio Geraldo Rezende de

; Hammond, Naomi

; Li, Yang

; Azevedo, Luciano Cesar Pontes de

; Cavalcanti, Alexandre Biasi

; Taniguchi, Leandro

; Gobatto, André

; Japiassú, André Miguel

; Bafi, Antonio Tonete

; Mazza, Bruno Franco

; Noritomi, Danilo Teixeira

; Dal-Pizzol, Felipe

; Bozza, Fernando

; Salluh, Jorge Ibrahin Figueira

; Westphal, Glauco Adrieno

; Soares, Márcio

; Assunção, Murillo Santucci César de

; Lisboa, Thiago

; Lobo, Suzana Margarete Ajeje

; Barbosa, Achilles Rohlfs

; Ventura, Adriana Fonseca

; Souza, Ailson Faria de

; Silva, Alexandre Francisco

; Toledo, Alexandre

; Reis, Aline

; Cembranel, Allan

; Rea Neto, Alvaro

; Gut, Ana Lúcia

; Justo, Ana Patricia Pierre

; Santos, Ana Paula

; Albuquerque, André Campos D. de

; Scazufka, André

; Rodrigues, Antonio Babo

; Fernandino, Bruno Bonaccorsi

; Silva, Bruno Goncalves

; Vidal, Bruno Sarno

; Pinheiro, Bruno Valle

; Pinto, Bruno Vilela Costa

; Feijo, Carlos Augusto Ramos

; Abreu Filho, Carlos de

; Bosso, Carlos Eduardo da Costa Nunes

; Moreira, Carlos Eduardo Nassif

; Ramos, Carlos Henrique Ferreira

; Tavares, Carmen

; Arantes, Cidamaiá

; Grion, Cintia

; Mendes, Ciro Leite

; Kmohan, Claudio

; Piras, Claudio

; Castro, Cristine Pilati Pileggi

; Lins, Cyntia

; Beraldo, Daniel

; Fontes, Daniel

; Boni, Daniela

; Castiglioni, Débora

; Paisani, Denise de Moraes

; Pedroso, Durval Ferreira Fonseca

; Mattos, Ederson Roberto

; Brito Sobrinho, Edgar de

; Troncoso, Edgar M. V.

; Rodrigues Filho, Edison Moraes

; Nogueira, Eduardo Enrico Ferrari

; Ferreira, Eduardo Leme

; Pacheco, Eduardo Souza

; Jodar, Euzebio

; Ferreira, Evandro L. A.

; Araujo, Fabiana Fernandes de

; Trevisol, Fabiana Schuelter

; Amorim, Fábio Ferreira

; Giannini, Fabio Poianas

; Santos, Fabrício Primitivo Matos

; Buarque, Fátima

; Lima, Felipe Gallego

; Costa, Fernando Antonio Alvares da

; Sad, Fernando Cesar dos Anjos

; Aranha, Fernando G.

; Ganem, Fernando

; Callil, Flavio

; Costa Filho, Francisco Flávio

; Dall´Arto, Frederico Toledo Campo

; Moreno, Geovani

; Friedman, Gilberto

; Moralez, Giulliana Martines

; Silva, Guilherme Abdalla da

; Costa, Guilherme

; Cavalcanti, Guilherme Silva

; Betônico, Gustavo Navarro

; Reis, Hélder

; Araujo, Helia Beatriz N.

; Hortiz Júnior, Helio Anjos

; Guimaraes, Helio Penna

; Urbano, Hugo

; Maia, Israel

; Santiago Filho, Ivan Lopes

; Farhat Júnior, Jamil

; Alvarez, Janu Rangel

; Passos, Joel Tavares

; Paranhos, Jorge Eduardo da Rocha

; Marques, José Aurelio

; Moreira Filho, José Gonçalves

; Andrade, Jose Neto

; Sobrinho, José Onofre de C

; Bezerra, Jose Terceiro de Paiva

; Alves, Juliana Apolônio

; Ferreira, Juliana

; Gomes, Jussara

; Sato, Karina Midori

; Gerent, Karine

; Teixeira, Kathia Margarida Costa

; Conde, Katia Aparecida Pessoa

; Martins, Laércia Ferreira

; Figueirêdo, Lanese

; Rezegue, Leila

; Tcherniacovsk, Leonardo

; Ferraz, Leone Oliveira

; Cavalcante, Liane

; Rabelo, Ligia

; Miilher, Lilian

; Garcia, Lisiane

; Tannous, Luana

; Hajjar, Ludhmila Abrahão

; Paciência, Luís Eduardo Miranda

; Cruz Neto, Luiz Monteiro da

; Bley, Macia Valeria

; Sousa, Marcelo Ferreira

; Puga, Marcelo Lourencini

; Romano, Marcelo Luz Pereira

; Nobrega, Marciano

; Arbex, Marcio

; Rodrigues, Márcio Leite

; Guerreiro, Márcio Osório

; Rocha, Marcone

; Alves, Maria Angela Pangoni

; Rosa, Maria Doroti

; Dias, Mariza D’Agostino

; Martins, Miquéias

; Oliveira, Mirella de

; Moretti, Miriane Melo Silveira

; Matsui, Mirna

; Messender, Octavio

; Santarém, Orlando Luís de Andrade

; Silveira, Patricio Júnior Henrique da

; Vassallo, Paula Frizera

; Antoniazzi, Paulo

; Gottardo, Paulo César

; Correia, Paulo

; Ferreira, Paulo

; Torres, Paulo

; Silva, Pedro Gabrile M. de Barros e

; Foernges, Rafael

; Gomes, Rafael

; Moraes, Rafael

; Nonato filho, Raimundo

; Borba, Renato Luis

; Gomes, Renato V

; Cordioli, Ricardo

; Lima, Ricardo

; López, Ricardo Pérez

; Gargioni, Ricardo Rath de Oliveira

; Rosenblat, Richard

; Souza, Roberta Machado de

; Almeida, Roberto

; Narciso, Roberto Camargo

; Marco, Roberto

; waltrick, Roberto

; Biondi, Rodrigo

; Figueiredo, Rodrigo

; Dutra, Rodrigo Santana

; Batista, Roseane

; Felipe, Rouge

; Franco, Rubens Sergio da Silva

; Houly, Sandra

; Faria, Sara Socorro

; Pinto, Sergio Felix

; Luzzi, Sergio

; Sant’ana, Sergio

; Fernandes, Sergio Sonego

; Yamada, Sérgio

; Zajac, Sérgio

; Vaz, Sidiner Mesquita

; Bezerra, Silvia Aparecida Bezerra

; Farhat, Tatiana Bueno Tardivo

; Santos, Thiago Martins

; Smith, Tiago

; Silva, Ulysses V. A.

; Damasceno, Valnei Bento

; Nobre, Vandack

; Dantas, Vicente Cés de Souza

; Irineu, Vivian Menezes

; Bogado, Viviane

; Nedel, Wagner

; Campos Filho, Walther

; Dantas, Weidson

; Viana, William

; Oliveira Filho, Wilson de

; Delgadinho, Wilson Martins

; Finfer, Simon

; Machado, Flavia Ribeiro

Revista Brasileira de Terapia Intensiva

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apr 2021, Volume 33 N. 2 Pages 206 - 218

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Descrever as práticas de ressuscitação volêmica em unidades de terapia intensiva brasileiras e compará-las com as de outros países participantes do estudo Fluid-TRIPS. Métodos: Este foi um estudo observacional transversal, prospectivo e internacional, de uma amostra de conveniência de unidades de terapia intensiva de 27 países (inclusive o Brasil), com utilização da base de dados Fluid-TRIPS compilada em 2014. Descrevemos os padrões de ressuscitação volêmica utilizados no Brasil em comparação com os de outros países e identificamos os fatores associados com a escolha dos fluidos. Resultados: No dia do estudo, foram incluídos 3.214 pacientes do Brasil e 3.493 pacientes de outros países, dos quais, respectivamente, 16,1% e 26,8% (p < 0,001) receberam fluidos. A principal indicação para ressuscitação volêmica foi comprometimento da perfusão e/ou baixo débito cardíaco (Brasil 71,7% versus outros países 56,4%; p < 0,001). No Brasil, a percentagem de pacientes que receberam soluções cristaloides foi mais elevada (97,7% versus 76,8%; p < 0,001), e solução de cloreto de sódio a 0,9% foi o cristaloide mais comumente utilizado (62,5% versus 27,1%; p < 0,001). A análise multivariada sugeriu que os níveis de albumina se associaram com o uso tanto de cristaloides quanto de coloides, enquanto o tipo de prescritor dos fluidos se associou apenas com o uso de cristaloides. Conclusão: Nossos resultados sugerem que cristaloides são usados mais frequentemente do que coloides para ressuscitação no Brasil, e essa discrepância, em termos de frequências, é mais elevada do que em outros países. A solução de cloreto de sódio 0,9% foi o cristaloide mais frequentemente prescrito. Os níveis de albumina sérica e o tipo de prescritor de fluidos foram os fatores associados com a escolha de cristaloides ou coloides para a prescrição de fluidos.

Abstract Objective: To describe fluid resuscitation practices in Brazilian intensive care units and to compare them with those of other countries participating in the Fluid-TRIPS. Methods: This was a prospective, international, cross-sectional, observational study in a convenience sample of intensive care units in 27 countries (including Brazil) using the Fluid-TRIPS database compiled in 2014. We described the patterns of fluid resuscitation use in Brazil compared with those in other countries and identified the factors associated with fluid choice. Results: On the study day, 3,214 patients in Brazil and 3,493 patients in other countries were included, of whom 16.1% and 26.8% (p < 0.001) received fluids, respectively. The main indication for fluid resuscitation was impaired perfusion and/or low cardiac output (Brazil: 71.7% versus other countries: 56.4%, p < 0.001). In Brazil, the percentage of patients receiving crystalloid solutions was higher (97.7% versus 76.8%, p < 0.001), and 0.9% sodium chloride was the most commonly used crystalloid (62.5% versus 27.1%, p < 0.001). The multivariable analysis suggested that the albumin levels were associated with the use of both crystalloids and colloids, whereas the type of fluid prescriber was associated with crystalloid use only. Conclusion: Our results suggest that crystalloids are more frequently used than colloids for fluid resuscitation in Brazil, and this discrepancy in frequencies is higher than that in other countries. Sodium chloride (0.9%) was the crystalloid most commonly prescribed. Serum albumin levels and the type of fluid prescriber were the factors associated with the choice of crystalloids or colloids for fluid resuscitation.

https://doi.org/10.5935/0103-507x.20210028 273 downloads

11.

Er3+/Yb3+-Doped GdVO4 Obtained by the Non-Hydrolytic Sol-Gel Route and Potential Application as Up-Conversion Thermometer
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Ferreira, Maria F.

; Sousa, Kalil Z. R. de

; Massarotto, Wagner L.

; Ricci, Emiliane G.

; Faria, Emerson H. de

; Ciuffi, Katia J.

; Sevic, Dragutin

; Rocha, Lucas A.

; Nassar, Eduardo J.

Journal of the Brazilian Chemical Society

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feb 2021, Volume 32 N. 2 Pages 376 - 384

Abstract: En | Text: En | PDF: En

The properties of lanthanides allow them to be used as contrast agents for magnetic resonance imaging, thereby helping to differentiate between tissues, organs, and pathologies more efficiently. Lanthanides contain thermosensitive energy levels that aid identification of cancer and healthy cells. This work investigates the GdVO4 matrix obtained by the non-hydrolytic sol-gel methodology and doped with the lanthanide ions Er3+ and Yb3+ at a 1:1 molar ratio. The efficiency of the optical parameters was analyzed on the basis of the Er3+ green emission after excitation in the infrared region, namely 980 nm. The temperature-dependent fluorescence intensity ratio (FIR) between the thermally coupled Er3+ levels (2H11/2 and 4S3/2 → 4I15/2) was evaluated. The Er3+ emission depended on the laser power. The calculated number of photons was 2 in this case. Temperatures ranging from 298.3 to 374.5 K were assessed, and the sensitivity varied from 1.2 to 1.9% K-1, respectively. The initial temperature was estimated.

https://doi.org/10.21577/0103-5053.20200189 227 downloads

12.

Prevalence evolution of SARS-CoV-2 infection in the city of São Paulo, 2020–2021
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Albuquerque, José Olimpio Moura de

; Kamioka, Gabriela Akemi

; Madalosso, Geraldine

; Costa, Selma Anequini

; Ferreira, Paula Bisordi

; Pino, Francisco Alberto

; Sato, Ana Paula Sayuri

; Carvalho, Ana Carolina Aguiar de

; Amorim, Ana Beatriz Pagliaro

; Aires, Caroline Cotrim

; Kataoka, Ana Paula Arruda Geraldes

; Savani, Elisa San Martin Mouriz

; Bessa, Thirsa Alvares Franco

; Aguiar, Breno Souza de

; Failla, Marcelo Antunes

; Santos, Edson Aparecido dos

; Brito, Edjane Maria Torreão

; Santos, Maria Cristina Honório dos

; Silva, Solange Maria Saboia e

; Caldeira, Luiz Artur Vieira

; Zamarco, Luiz Carlos

; Fonseca, Sandra Maria Sabino

; Lima, Marcia Maria de Cerqueira

; Marques, Ivanilda Argenau

; Silva, Fabiana Érica Vilanova da

; Glasser, Paula Regina

; Burihan, Patrícia Carla Piragibe Ramos

; Cavazzana, Cinthya Luzia

; Mello, Debora Silva de

; Pellini, Alessandra Cristina Guedes

; Nishio, Fernando Yoshiki

; Kian, Fernanda Miyashiro

; Braga, Elza de Santana

; Bertelli, Nilza Maria Piassi

; Fracini, Wagner

; Gonçalves, Marcelo Dell Áquila

; Zular, Paulete Secco

; Piva, Regiane de Santana

; Masi, Eduardo

Revista de Saúde Pública

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2021, Volume 55 elocation 62

Abstract: En | Text: En | PDF: En

ABSTRACT OBJECTIVE To estimate the evolution of the prevalence of SARS-CoV-2 virus infection among residents aged 18 years or over in the municipality of São Paulo. METHODS This is a population-based household survey conducted every 15 days, between June and September 2020, and January and February 2021. In total, the study comprised 11 phases. The presence of antibodies against SARS-CoV-2 was identified in venous blood using a lateral flow test, Wondfo Biotech. In the last phase, the researchers combined it with an immunoenzymatic test, Euroimmun. The participants also answered a semi-structured questionnaire on sociodemographic and economic factors, and on social distancing measures. Prevalence estimates and the 95% confidence interval were estimated according to regions, Human Development Index, sex, age group, ethnicity, education, income, and variables associated with risk or prevention of infection. To compare the frequencies among the categories of each variable, the chi-square test with Rao-Scott correction was used, considering a significance level of 5%. RESULTS In total, 23,397 individuals were interviewed and had their samples collected. The estimated prevalence of antibodies against SARS-CoV-2 ranged from 9.7% (95%CI: 7.9–11.8%) to 25.0% (95%CI: 21.7–28.7). The prevalence of individuals with antibodies against the virus was higher among black and brown people, people with lower schooling and income, and among residents of regions with lower Human Development Index. The lowest prevalences were associated with recommended measures of disease protection. The proportion of asymptomatic infection was 45.1%. CONCLUSION The estimated prevalence of the infection was lower than the cumulative incidence variation, except for the last phase of the study. The differences in prevalence estimates observed among subpopulations showed social inequality as a risk of infection. The lower prevalence observed among those who could follow prevention measures reinforce the need to maintain social distancing measures as a way to prevent SARS-CoV-2 infection.

https://doi.org/10.11606/s1518-8787.2021055003970

13.

Prevalence evolution of SARS-CoV-2 infection in the city of São Paulo, 2020–2021
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Albuquerque, José Olimpio Moura de

; Kamioka, Gabriela Akemi

; Madalosso, Geraldine

; Costa, Selma Anequini

; Ferreira, Paula Bisordi

; Pino, Francisco Alberto

; Sato, Ana Paula Sayuri

; Carvalho, Ana Carolina Aguiar de

; Amorim, Ana Beatriz Pagliaro

; Aires, Caroline Cotrim

; Kataoka, Ana Paula Arruda Geraldes

; Savani, Elisa San Martin Mouriz

; Bessa, Thirsa Alvares Franco

; Aguiar, Breno Souza de

; Failla, Marcelo Antunes

; Santos, Edson Aparecido dos

; Brito, Edjane Maria Torreão

; Santos, Maria Cristina Honório dos

; Silva, Solange Maria Saboia e

; Caldeira, Luiz Artur Vieira

; Zamarco, Luiz Carlos

; Fonseca, Sandra Maria Sabino

; Lima, Marcia Maria de Cerqueira

; Marques, Ivanilda Argenau

; Silva, Fabiana Érica Vilanova da

; Glasser, Paula Regina

; Burihan, Patrícia Carla Piragibe Ramos

; Cavazzana, Cinthya Luzia

; Mello, Debora Silva de

; Pellini, Alessandra Cristina Guedes

; Nishio, Fernando Yoshiki

; Kian, Fernanda Miyashiro

; Braga, Elza de Santana

; Bertelli, Nilza Maria Piassi

; Fracini, Wagner

; Gonçalves, Marcelo Dell Áquila

; Zular, Paulete Secco

; Piva, Regiane de Santana

; Masi, Eduardo

Revista de Saúde Pública

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2021, Volume 55 elocation 62

Abstract: En | Text: En | PDF: En

https://doi.org/10.11606/s1518-8787.2021055003970 43 downloads

14.

COMVC-19: A Program to protect healthcare workers’ mental health during the COVID-19 Pandemic. What we have learned
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Fukuti, Pedro

; Uchôa, Caroline Louise Mesquita

; Mazzoco, Marina Flaborea

; Cruz, Isabella D'Andrea Garcia da

; Echegaray, Mariana V.F.

; Humes, Eduardo de Castro

; Silveira, Júlia Belizário

; Santi, Talita Di

; Miguel, Euripedes Constantino

; Corchs, Felipe

; Fatori, Daniel

; Campello, Guilherme

; Oliveira, Gabriel M. de

; Argolo, Felipe C.

; Ferreira, Felipe de M.

; Machado, Gustavo

; Argeu, Adriana

; Oliveira, Graça Maria Ramos de

; Serafim, Antônio de Pádua

; Siqueira, Luciana de Lima

; Rossi, Luciane de

; Rios, Izabel Cristina

; Oliveira, Talita Rodrigues de

; Antoniazzi, Leilane C. K.

; Gagliotti, Daniel Augusto Mori

; Abelama Neto, Emílio

; Oliveira Junior, Paulo Novais de

; Correia, Aline Villalobo

; Gonçalves, Luca Schilling

; Tortato, Liana Silva

; Busato, Wagner Machado Moraes

; Guimarães-Fernandes, Flávio

; Alves, Marcos

; Leite Netto, Oswaldo Ferreira

; Schoueri, Patrícia de Campos Lindenberg

; Roque, Márcio de Assis

; Merlin, Silvia Stahl

; Boer, Giovana Cardoso Machado

; Sallet, Paulo Clemente

; Malbergier, André

; Spedo, Mariana Abrahão

; Kamitsuji, Carla Satie

; Faria, Elizabeth de

; Moreira, Moacyr Vergara de Godoy

; Kaufman, Arthur

; Abdo, Carmita

; Scanavino, Marco de Tubino

; Lancman, Selma

; Tavares, Hermano

; Polanczyk, Guilherme

; Brunoni, André R.

; Forlenza, Orestes V.

; Barros-Filho, Tarcísio Eloy Pessoa de

Clinics

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2021, Volume 76 elocation e2631

Abstract: En | Text: En | PDF: En

OBJECTIVE: In 2020, the COVID-19 pandemic brought a work and stress overload to healthcare workers, increasing their vulnerability to mental health impairments. In response, the authors created the COMVC-19 program. The program offered preventive actions and mental health treatment for the 22,000 workers of The Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP). This paper aims to describe its implementation and share what we have learned from this experience. METHODS: Workers were able to easily access the program through a 24/7 hotline. Additionally, a mobile phone app that screened for signs and symptoms of emotional distress and offered psychoeducation and/or referral to treatment was made available. Data from both these sources as well as any subsequent psychiatric evaluations were collected. RESULTS: The first 20 weeks of our project revealed that most participants were female, and part of the nursing staff working directly with COVID-19 patients. The most frequently reported symptoms were: anxiety, depression and sleep disturbances. The most common diagnoses were Adjustment, Anxiety, and Mood disorders. CONCLUSIONS: Implementing a mental health program in a multimodal intervention was feasible in a major quaternary public hospital. Our data also suggests that preventive actions should primarily be aimed at anxiety and depression symptoms, with a particular focus on the nursing staff.

https://doi.org/10.6061/clinics/2021/e2631

15.

Chronic use of hydroxychloroquine did not protect against COVID-19 in a large cohort of patients with rheumatic diseases in Brazil
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Pileggi, Gecilmara Salviato

; Ferreira, Gilda Aparecida

; Gomides Reis, Ana Paula Monteiro

; Reis Neto, Edgard Torres

; Abreu, Mirhelen Mendes

; Albuquerque, Cleandro Pires

; Araújo, Nafice Costa

; Bacchiega, Ana Beatriz

; Bianchi, Dante Valdetaro

; Bica, Blanca

; Bonfa, Eloisa Duarte

; Borba, Eduardo Ferreira

; Brito, Danielle Christinne Soares Egypto

; Duarte, Ângela Luzia Branco Pinto

; Santo, Rafaela Cavalheiro Espírito

; Fernandes, Paula Reale

; Guimarães, Mariana Peixoto

; Gomes, Kirla Wagner Poti

; Kakehasi, Adriana Maria

; Klumb, Evandro Mendes

; Lanna, Cristina Costa Duarte

; Marques, Claudia Diniz Lopes

; Monticielo, Odirlei André

; Mota, Licia Maria Henrique

; Munhoz, Gabriela Araújo

; Paiva, Eduardo Santos

; Pereira, Helena Lucia Alves

; Provenza, José Roberto

; Ribeiro, Sandra Lucia Euzébio

; Rocha Junior, Laurindo Ferreira

; Sampaio, Camila Santana Justo Cintra

; Sampaio, Vanderson Souza

; Sato, Emília Inoue

; Skare, Thelma

; de Souza, Viviane Angelina

; Valim, Valeria

; Lacerda, Marcus Vinícius Guimarães

; Xavier, Ricardo Machado

; Pinheiro, Marcelo Medeiros

Advances in Rheumatology

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2021, Volume 61 elocation 60

Abstract: En | Text: En | PDF: En

Abstract Background: There is a lack of information on the role of chronic use of hydroxychloroquine during the SARS-CoV-2 outbreak. Our aim was to compare the occurrence of COVID-19 between rheumatic disease patients on hydroxychloroquine with individuals from the same household not taking the drug during the first 8 weeks of community viral transmission in Brazil. Methods: This baseline cross-sectional analysis is part of a 24-week observational multi-center study involving 22 Brazilian academic outpatient centers. All information regarding COVID-19 symptoms, epidemiological, clinical, and demographic data were recorded on a specific web-based platform using telephone calls from physicians and medical students. COVID-19 was defined according to the Brazilian Ministry of Health (BMH) criteria. Mann-Whitney, Chi-square and Exact Fisher tests were used for statistical analysis and two binary Final Logistic Regression Model by Wald test were developed using a backward-stepwise method for the presence of COVID-19. Results: From March 29th to May 17st, 2020, a total of 10,443 participants were enrolled, including 5166 (53.9%) rheumatic disease patients, of whom 82.5% had systemic erythematosus lupus, 7.8% rheumatoid arthritis, 3.7% Sjögren’s syndrome and 0.8% systemic sclerosis. In total, 1822 (19.1%) participants reported flu symptoms within the 30 days prior to enrollment, of which 3.1% fulfilled the BMH criteria, but with no significant difference between rheumatic disease patients (4.03%) and controls (3.25%). After adjustments for multiple confounders, the main risk factor significantly associated with a COVID-19 diagnosis was lung disease (OR 1.63; 95% CI 1.03-2.58); and for rheumatic disease patients were diagnosis of systemic sclerosis (OR 2.8; 95% CI 1.19-6.63) and glucocorticoids above 10 mg/ day (OR 2.05; 95% CI 1.31-3.19). In addition, a recent influenza vaccination had a protective effect (OR 0.674; 95% CI 0.46-0.98). Conclusion: Patients with rheumatic disease on hydroxychloroquine presented a similar occurrence of COVID-19 to household cohabitants, suggesting a lack of any protective role against SARS-CoV-2 infection. Trial registration Brazilian Registry of Clinical Trials (ReBEC; RBR - 9KTWX6).

https://doi.org/10.1186/s42358-021-00217-0 22 downloads

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