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Resumo O objetivo do artigo é avaliar a prevalência de adesão ao tratamento anti-hipertensivo na população brasileira, com base nos estudos revisados por pares, que utilizaram instrumentos elaborados e/ou adaptados exclusivamente para este fim. Revisão sistemática com meta-análise, baseada nas recomendações do Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). A busca foi realizada nas bases BDENF, SciELO, Cuiden, PsycINFOe, CINAHL, Embase, LILACS, MEDLINE, e nos buscadores acadêmicos AgeLine, Google Scholar e ScienceDirect. O protocolo foi registrado no PROSPERO (CRD42021292689). Modelos de efeitos aleatórios foram usados para meta-análise das prevalências obtidas dos estudos individuais. Incluíram-se 104 estudos na meta-análise sobre tratamento anti-hipertensivo na população brasileira, totalizando 38.299 pacientes. O instrumento mais utilizado foi o teste de Morisky-Green de quatro itens (49,5%). A prevalência de adesão estimada pela foi de 44,4% (IC95%: 39,12%-49,94%, I2 = 91,17, p < 0,001), apresentando alta heterogeneidade. A prevalência de adesão ao tratamento anti-hipertensivo encontrada nos estudos nacionais foi insatisfatória, demonstrando que essa problemática continua sendo um grande desafio. antihipertensivo anti hipertensivo brasileira pares eou ou fim metaanálise, metaanálise meta análise, análise MetaAnalyses Meta Analyses PRISMA. PRISMA . (PRISMA) BDENF SciELO Cuiden PsycINFOe CINAHL Embase LILACS MEDLINE AgeLine ScienceDirect CRD42021292689. CRD42021292689 CRD (CRD42021292689) individuais Incluíramse Incluíram se 10 38299 38 299 38.29 pacientes MoriskyGreen Morisky Green 49,5%. 495 49,5% 49 5 (49,5%) 444 44 4 44,4 IC95% IC95 IC (IC95% 39,12%49,94%, 39124994 39,12% 49,94%, 39 12 94 39,12%-49,94% I 9117 91 17 91,17 0,001, 0001 0,001 , 0 001 0,001) heterogeneidade insatisfatória desafio (PRISMA CRD4202129268 (CRD42021292689 1 3829 3 29 38.2 49,5 (49,5% 44, IC9 (IC95 39,12%49,94% 3912499 3912 39,12 4994 49,94% 9 39,12%-49,94 911 91,1 000 0,00 00 CRD420212926 (CRD4202129268 382 2 38. 49, (49,5 (IC9 39,12%49,94 391249 391 39,1 499 49,94 39,12%-49,9 91, 0,0 CRD42021292 (CRD420212926 (49, (IC 39,12%49,9 39124 39, 49,9 39,12%-49, 0, CRD4202129 (CRD42021292 (49 39,12%49, 39,12%-49 CRD420212 (CRD4202129 (4 39,12%49 39,12%-4 CRD42021 (CRD420212 ( 39,12%4 39,12%- CRD4202 (CRD42021 CRD420 (CRD4202 CRD42 (CRD420 CRD4 (CRD42 (CRD4 (CRD

Abstract This article aims to evaluate the adherence to antihypertensive treatment prevalence in the Brazilian population based on peer-reviewed studies which used instruments exclusively designed and/or adapted for this purpose. A systematic review with meta-analysis based on the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The search was carried out in the BDENF, SciELO, Cuiden, PsycINFOe, CINAHL, Embase, LILACS, and MEDLINE databases, as well as the AgeLine, Google Scholar and ScienceDirect academic search engines. The protocol was registered with PROSPERO (CRD42021292689). Random effects models were used for a meta-analysis of the prevalence obtained from individual studies. A total of 104 studies were included in the meta-analysis on antihypertensive treatment in the Brazilian population, totaling 38,299 patients. The most used instrument was the four-item Morisky-Green Test (49.5%). The adherence prevalence estimated by the meta-analysis was 44.4% (95%CI: 39.12%-49.94%, I2 = 91.17, p < 0.001), showing high heterogeneity. The adherence to antihypertensive treatment prevalence found in national studies was unsatisfactory, demonstrating that this problem continues to be a major challenge. peerreviewed peer reviewed andor or purpose metaanalysis meta analysis MetaAnalyses Meta Analyses PRISMA. PRISMA . (PRISMA) BDENF SciELO Cuiden PsycINFOe CINAHL Embase LILACS databases AgeLine engines CRD42021292689. CRD42021292689 CRD (CRD42021292689) 10 38299 38 299 38,29 patients fouritem four item MoriskyGreen Morisky Green 49.5%. 495 49.5% 49 5 (49.5%) 444 44 4 44.4 95%CI 95CI CI 95 (95%CI 39.12%49.94%, 39124994 39.12% 49.94%, 39 12 94 39.12%-49.94% I 9117 91 17 91.17 0.001, 0001 0.001 , 0 001 0.001) heterogeneity unsatisfactory challenge (PRISMA CRD4202129268 (CRD42021292689 1 3829 3 29 38,2 49.5 (49.5% 44. 9 39.12%49.94% 3912499 3912 39.12 4994 49.94% 39.12%-49.94 911 91.1 000 0.00 00 CRD420212926 (CRD4202129268 382 2 38, 49. (49.5 39.12%49.94 391249 391 39.1 499 49.94 39.12%-49.9 91. 0.0 CRD42021292 (CRD420212926 (49. 39.12%49.9 39124 39. 49.9 39.12%-49. 0. CRD4202129 (CRD42021292 (49 39.12%49. 39.12%-49 CRD420212 (CRD4202129 (4 39.12%49 39.12%-4 CRD42021 (CRD420212 ( 39.12%4 39.12%- CRD4202 (CRD42021 CRD420 (CRD4202 CRD42 (CRD420 CRD4 (CRD42 (CRD4 (CRD

https://doi.org/10.1590/1413-81232024298.19282022

Development and Content Validation of an Instrument Covering Care for Pregnant Women with Sickle Cell Disease
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Almeida Santos, Eliene

; Ferreira, Silvia Lucia

; Araújo Pinto, Karina

; Cândida Cordeiro, Rosa

; Batista da Silva, Ueigla

; Boa Sorte Fernandes, Elionara Teixeira

Aquichan

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mar 2024, Volume 24 N. 1 elocation e2415

Abstract: Pt Es En | Text: Pt Es En | PDF: Pt | PDF: Es | PDF: En

Resumo Introdução: a escassez de debates sobre o cuidado de enfermagem às gestantes com doença falciforme no país e a urgente necessidade de intervenção e melhorias na assistência de enfermagem prestada às essas mulheres, motivaram este estudo. Além disso, em instrumentos para uso em pesquisa e/ou na prática clínica, a validade é um atributo essencial. Objetivo: desenvolver e validar um instrumento para cuidados às gestantes com doença falciforme. Materiais e método: estudo metodológico, de validação de conteúdo com juízas(es) especialistas. O instrumento foi estruturado com 19 diagnósticos de enfermagem que abordaram as dimensões biológica, psíquica e social, e 126 intervenções de enfermagem. Utilizou-se a técnica Delphi, com participação de 18 juízas(es). Os resultados foram analisados por meio do índice de validade de conteúdo e nível de concordância acima de 0,80. Resultados: dos 145 itens analisados, 22 (15,17 %) apresentaram índice de validade de conteúdo < 0,80, e os ajustes sugeridos pelas(os) juízas(es) foram implementados. O índice de validade de conteúdo geral do instrumento foi calculado em 0,87. O instrumento alcançou parámetros aceitáveis de validade de conteúdo, segundo o critério utilizado. Conclusões: destaca-se o potencial do instrumento, que pode ser aprimorado a partir do seu uso, como recurso na orientação das práticas de enfermagem voltadas às mulheres grávidas com doença falciforme, nos âmbitos da atenção primária à saúde e da rede hospitalar.

Resumen Introducción: la escasez de debates sobre la atención de enfermería a gestantes con anemia de células falciformes en el país y la urgente necesidad de intervención y mejora de los cuidados de enfermería prestados a esas mujeres motivaron la realización de este estudio. Además, la validez es un atributo esencial en los instrumentos para uso en investigación y/o práctica clínica. Objetivo: elaborar y validar un instrumento de atención a gestantes con anemia de células falciformes. Material y método: estudio metodológico, de validación de contenido con jueces/as expertos/as. El instrumento se estructuró con 19 diagnósticos de enfermería que abordaban las dimensiones biológica, psicológica y social, y 126 intervenciones de enfermería. Se utilizó la técnica Delphi, con la participación de 18 jueces/as. Los resultados se analizaron utilizando el índice de validez de contenido y un nivel de acuerdo superior a 0,80. Resultados: de los 145 ítems analizados, 22 (15,17 %) tenían un índice de validez de contenido < 0,80, y se aplicaron los ajustes sugeridos por los/las jueces/as. El índice global de validez de contenido del instrumento se calculó en 0,87. El instrumento alcanzó parámetros de validez de contenido aceptables, según los criterios utilizados. Conclusiones: se destaca el potencial del instrumento, que puede ser perfeccionado a través de su utilización como recurso para orientar las prácticas de enfermería dirigidas a gestantes con anemia de células falciformes, tanto en la atención primaria de salud como en la red hospitalaria.

Abstract Introduction: The lack of discussions on nursing care for pregnant women with sickle cell disease in Brazil and the urgent need for intervention and improvements in the nursing care provided to these women sparked this study. In addition, validity is an essential attribute for instruments used in research and/or clinical practice. Objective: To develop and validate an instrument covering the care of pregnant women with sickle cell disease. Materials and methods: This is a methodological, content validation study conducted with specialist judges. The instrument was structured with 19 nursing diagnoses that addressed the biological, psychological, and social dimensions, as well as 126 nursing interventions. The Delphi technique was used with the participation of 18 judges. The results were analyzed using the content validity index and a level of agreement above 0.80. Results: Of the 145 items analyzed, 22 (15.17 %) scored a content validity index < 0.80, and the adjustments suggested by the judges were implemented. The instrument’s general content validity index was calculated at 0.87. The instrument reached acceptable content validity parameters, according to the criteria used. Conclusions: The instrument’s potential stands out, and it can be improved through its use as a resource for guiding nursing practices directed to pregnant women with sickle cell disease, both in primary health care and in hospital networks.

https://doi.org/10.5294/aqui.2024.24.1.5

HIGH-INTENSITY INTERVAL TRAINING IN PEOPLE WITH SPINAL CORD INJURY: A SYSTEMATIC REVIEW HIGHINTENSITY HIGH INTENSITY INJURY
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Silva, Carlos Mariano Aguiar Ferreira da

; Sá, Karina Santos Guedes de

; Gorla, José Irineu

; Flores, Lucinar Jupir Forner

; Silva, Marília de Passos Magno e

; Coswig, Victor Silveira

; Silva, Anselmo de Athayde Costa e

Revista Brasileira de Medicina do Esporte

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2024, Volume 30 elocation e2022_0193

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

RESUMEN Objetivo: Analizar los efectos del entrenamiento interválico de alta intensidad (HIIT) sobre los parámetros cardiometabólicos, fitness cardiorrespiratorio y recopilar los tipos de HIIT más utilizados en el entrenamiento en adultos con lesión medular (LME). Métodos: Se trata de una revisión sistemática, para lo cual se realizaron búsquedas en bases de datos electrónicas PubMed/Medline, Science Direct y Google Scholar. Se incluyeron estudios que I) necesitaban aplicar entrenamiento HIIT en II) adultos con SCI y analizar III) aspectos cardiometabólicos y aptitud cardiorrespiratoria. Dos revisores independientes seleccionaron los artículos para su inclusión, extrajeron sus datos y evaluaron su calidad metodológica. Resultados: De los 654 estudios encontrados, se analizaron 12 estudios, 11 pre y post intervención y 1 grupo control (GC) con un total de 106 participantes. Los resultados previos y posteriores a la intervención HIIT revelaron una mejora significativa en la aptitud cardiorrespiratoria y los aspectos cardiometabólicos (VO2pico, LDH, HDL, resistencia a la insulina). Los resultados de GC revelaron una mejora significativa en la aptitud cardiorrespiratoria observada del grupo de intervención (HIIT) en comparación con el grupo de intensidad moderada-baja (GC). Siete estudios utilizaron el ergómetro de brazo como la modalidad principal de ejercicio. Dos estudios describieron la estimulación eléctrica funcional (EEF) realizada con el ergómetro de brazo más la estimulación eléctrica en los miembros inferiores. Ninguno informó la dinámica de la frecuencia cardíaca durante el período de estudio. Conclusiones: El entrenamiento intervalos de alta intensidad mejora la condición física y la salud cardiometabólica en adultos con LME. Evidencia de nivel II; Revisión sistemática de estudios de nivel II. Objetivo (HIIT LME . (LME) Métodos PubMedMedline PubMed Medline PubMed/Medline Scholar I II III inclusión metodológica Resultados 65 encontrados (GC 10 participantes VO2pico, VO2pico VOpico VO pico (VO2pico LDH HDL insulina. insulina insulina) moderadabaja moderada baja GC. ejercicio EEF (EEF inferiores estudio Conclusiones (LME 6

ABSTRACT Objective: Analyze the effects of high-intensity interval training (HIIT) on cardiometabolic parameters, and cardiorespiratory fitness to compile the most used HIIT training types in adults with spinal cord injury (SCI). Methods: This is a systematic review of searches performed in the electronic databases PubMed / Medline, Science Direct, and Google Scholar. Studies included I) needed to apply HIIT training II) adults with SCI to analyze III) cardiometabolic aspects and cardiorespiratory fitness. Two independent reviewers selected the articles for inclusion, extracted their data, and assessed their methodological quality. Results: 654 studies were found. Thus, 12 studies, 11 pre- and post-intervention, and one control group (CG) with 106 participants were analyzed. Pre- and post-HIITT intervention results revealed significant improvement in cardiorespiratory fitness and cardiometabolic aspects (VO2peak, LDH, HDL, insulin resistance). In addition, GC results revealed significant improvement in cardiorespiratory fitness observed in the intervention group (HIIT) compared to the moderate-low intensity (GC) group. Seven studies used the arm ergometer as the primary exercise modality. Two studies described functional electrical stimulation (FES) performed with the arm ergometer plus electrical stimulation in the lower limbs. None reported heart rate dynamics during the study period. Conclusion: High-intensity interval training improves physical fitness and cardiometabolic health in adults with SCI. Evidence level II; Systematic Review of level II studies. Objective highintensity high (HIIT parameters . (SCI) Methods Medline Direct Scholar I III inclusion data quality Results 65 found Thus 1 pre postintervention, postintervention post intervention, post-intervention CG (CG 10 analyzed Pre postHIITT HIITT VO2peak, VO2peak VOpeak VO peak (VO2peak LDH HDL resistance. resistance resistance) addition moderatelow moderate low (GC modality FES (FES limbs period Conclusion Highintensity High (SCI 6

RESUMO Objetivo: Analisar os efeitos do treinamento intervalado de alta intensidade (HIIT) nos parâmetros cardiometabólicos, aptidão cardiorrespiratória e compilar os tipos de HIIT mais utilizados no treinamento em adultos com lesão da medula espinhal (LME). Métodos: Trata-se de revisão sistemática, para a qual foram realizadas pesquisas nas bases de dados eletrônicas PubMed / Medline, Science Direct e Google Scholar. Foram incluídos estudos em que I) o treinamento HIIT era aplicado em II) adultos com LME e analisaram III) os aspectos cardiometabólicos e aptidão cardiorrespiratória. Dois revisores independentes selecionaram os artigos para a inclusão, extraindo seus dados e avaliarando a sua qualidade metodológica. Resultados: 654 estudos foram encontrados. Desses, 12 estudos, 11 pré e pós intervenção e 1 grupo controle (GC) com um total de 106 participantes foram analisados. Resultados pré e pós intervenção de HIIT revelaram significante melhora na aptidão cardiorrespiratória e aspectos cardiometabólicos (VO2pico, LDH, HDL, resistência à insulina). Resultados do GC revelaram uma significativa melhoria na aptidão cardiorrespiratória observada no grupo de intervenção (HIIT) em relação ao grupo de intensidade moderada-baixa (GC). Sete estudos usaram o ergômetro de braço como modalidade de exercício primária. Dois estudos descreveram a estimulação elétrica funcional (EEF) realizada com o ergômetro de braço adicionando estimulação elétrica nos membros inferiores. Nenhum relatou a dinâmica da frequência cardíaca durante o período do estudo. Conclusão: O treinamento intervalado de alta intensidade melhora a aptidão física e a saúde cardiometabólica em adultos com LME. Nível de evidência II; Revisão sistemática de Estudos de Nível II. Objetivo (HIIT . (LME) Métodos Tratase Trata se Medline Scholar I II III inclusão metodológica 65 encontrados Desses (GC 10 analisados VO2pico, VO2pico VOpico VO pico (VO2pico LDH HDL insulina. insulina insulina) moderadabaixa moderada baixa GC. primária EEF (EEF inferiores estudo Conclusão (LME 6

https://doi.org/10.1590/1517-8692202430012022_0193i

Acesso e qualidade da alimentação: percepção da população em situação de rua alimentação
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la Cerda, Carolina Moraes Preihsner de

; Soares, Giovanna Martins e

; Pinheiro, Ana Karina Bezerra

; Lacthim, Sheila Aparecida Ferreira

; Dias, André Luiz Freitas

; Arcencio, Ricardo Alexandre

; Freitas, Giselle Lima de

Acta Paulista de Enfermagem

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2024, Volume 37 elocation eAPE02361

Abstract: Es Pt En | Text: Es Pt En | PDF: Es | PDF: Pt | PDF: En

Resumen Objetivo Comprender la percepción del acceso y de la calidad de la alimentación según personas en situación de calle. Métodos Estudio descriptivo cualitativo, realizado en un Centro de Referencia de Personas de la Calle en la región centro-sur de Belo Horizonte (Minas Gerais). Se utilizó un guion semiestructurado para realizar entrevistas a 18 participantes. La recopilación de datos se realizó entre diciembre de 2020 y enero de 2021. El análisis temático del material, propuesto por Bardin, permitió la elaboración de tres categorías empíricas. Resultados El público entrevistado era masculino, de 43 años de edad promedio y tiempo promedio de situación de calle de 44,6 meses. El acceso a la alimentación fue proveniente de donaciones de alimentos, comidas en instituciones gubernamentales y adquisiciones al disponer de ingresos. Las personas relataron dificultades con relación a la cantidad y calidad de los alimentos, a la adquisición de comida los fines de semana, a los sentimientos de miedo y angustia ante el hambre, a la falta de alimentos y al estigma social, agravados por el COVID-19. Conclusión Ante el escenario de iniquidades sociales, el derecho al acceso a la alimentación no está garantizado, por lo cual es necesario implementar políticas públicas de protección social que garanticen los derechos básicos. cualitativo centrosur centro sur Minas Gerais. Gerais . Gerais) 1 participantes 202 2021 material Bardin empíricas masculino 4 446 44 6 44, meses ingresos semana hambre COVID19. COVID19 COVID 19. 19 COVID-19 sociales garantizado básicos 20 COVID1 COVID-1 2 COVID-

Resumo Objetivo Compreender a percepção do acesso e da qualidade da alimentação para a população em situação de rua. Métodos Estudo descritivo qualitativo, realizado em um Centro de Referência da População de Rua na região centro-sul de Belo Horizonte (MG). Utilizou-se roteiro semiestruturado para a realização das entrevistas de 18 participantes. A coleta de dados ocorreu entre dezembro de 2020 e janeiro de 2021. A análise temática do material, proposta por Bardin, possibilitou a elaboração de três categorias empíricas. Resultados O público entrevistado era masculino, com idade média de 43 anos e tempo médio de situação de rua de 44,6 meses. O acesso à alimentação foi proveniente das doações de alimentos, refeições em instituições governamentais e aquisições ao dispor de renda. Foram relatadas dificuldades quanto à quantidade e qualidade dos alimentos, à aquisição das refeições nos fins de semana, aos sentimentos de medo e angústia perante a fome, à falta do alimento e pelo estigma social, agravados pela COVID-19. Conclusão Diante do cenário de iniquidades sociais, o direito ao acesso à alimentação não é garantido, sendo necessária a implementação de políticas públicas de proteção social que garantam os direitos básicos. qualitativo centrosul centro sul MG. MG . (MG) Utilizouse Utilizou se 1 participantes 202 2021 material Bardin empíricas masculino 4 446 44 6 44, meses alimentos renda semana fome COVID19. COVID19 COVID 19. 19 COVID-19 sociais garantido básicos (MG 20 COVID1 COVID-1 2 COVID-

Abstract Objective To understand the perception of access to food and food quality for the street population. Methods This qualitative descriptive study was performed in a Reference Center for the Homeless Population in the south-central region of Belo Horizonte (MG). A semi-structured script was used to conduct interviews with 18 participants. Data collection occurred between December 2020 and January 2021. The thematic analysis of the material, as proposed by Bardin, made it possible to elaborate three empirical categories. Results The public interviewed was male, with a mean age of 43 years, and a mean time on the streets of 44.6 months. Access to food came from donations, meals at government institutions, and acquisition when income was available. Difficulties were reported regarding the quantity and quality of food, acquisition of meals on weekends, feelings of fear and anguish in the face of hunger, lack of food, and social stigma, which were aggravated by COVID-19. Conclusion As in this scenario of social inequalities the access to food is not guaranteed, implementing public policies of social protection is necessary to guarantee basic rights. population southcentral south central MG. MG . (MG) semistructured semi structured 1 participants 202 2021 material Bardin categories male 4 years 446 44 6 44. months donations institutions available weekends hunger stigma COVID19. COVID19 COVID 19. 19 COVID-19 guaranteed rights (MG 20 COVID1 COVID-1 2 COVID-

https://doi.org/10.37689/acta-ape/2024ao0002361

The influence of growth time on the identification of Bartonella henselae strains by MALDI-TOF mass spectrometry MALDITOF MALDI TOF
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Lins, Karina de Almeida

; Piveta, Cristiane Santos Cruz

; Levy, Carlos Emilio

; Drummond, Marina Rovani

; Santos, Luciene Silva dos

; Sussulini, Alessandra

; Velho, Paulo Eduardo Neves Ferreira

Revista do Instituto de Medicina Tropical de São Paulo

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2024, Volume 66 elocation e9

Abstract: En | Text: En | PDF: En

ABSTRACT Bartonella spp. are bacteria responsible for neglected diseases worldwide. Bartonella henselae is the species most associated with human infections. It is associated with a large spectrum of clinical manifestations and is potentially fatal. The identification of Bartonella spp. is considered a challenge in clinical routine. These bacteria are fastidious, and the time required to isolate them varies from one to six weeks. MALDI-TOF mass spectrometry has emerged as an application for research on Bartonella spp. , and has still been little explored. We investigated whether three different B. henselae strains with different growth times—14 and 28 days—could be correctly identified by MALDI-TOF mass spectra fingerprint comparison and matching. We found that the spectra from strains with different growth times do not match each other, leading to misidentification. We suggest creating database entries with multiple spectra from strains with different growth times to increase the chances of accurate identification of Bartonella spp. by MALD-TOF MS. spp worldwide infections fatal routine fastidious weeks MALDITOF MALDI TOF explored B times14 14 times—1 2 dayscould days could matching other misidentification MALDTOF MALD MS times1 1 times—

https://doi.org/10.1590/s1678-9946202466009

Adesão ao tratamento medicamentoso anti-hipertensivo no Brasil: revisão sistemática e meta-análise
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Coelho, Juliana Chaves

; Guimarães, Mayra Cristina da Luz Pádua

; Vaz, Ana Katly Martins Gualberto

; Meira, Karina Cardoso

; Santos, Juliano dos

; Lee, Renata Jae Won

; Drager, Luciano Ferreira

; Pierin, Angela Maria Geraldo

Ciência & Saúde Coletiva

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2024, Volume 29 N. 8 elocation e19282022

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232024298.19282022

Prospective, randomized, controlled trial assessing the effects of a driving pressure–limiting strategy for patients with acute respiratory distress syndrome due to community-acquired pneumonia (STAMINA trial): protocol and statistical analysis plan Prospective randomized pressurelimiting pressure limiting communityacquired community acquired STAMINA trial)
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Maia, Israel Silva

; Medrado Jr, Fernando Azevedo

; Tramujas, Lucas

; Tomazini, Bruno Martins

; Oliveira, Júlia Souza

; Sady, Erica Regina Ribeiro

; Barbante, Letícia Galvão

; Nicola, Marina Lazzari

; Gurgel, Rodrigo Magalhães

; Damiani, Lucas Petri

; Negrelli, Karina Leal

; Miranda, Tamiris Abait

; Santucci, Eliana

; Valeis, Nanci

; Laranjeira, Ligia Nasi

; Westphal, Glauco Adrieno

; Fernandes, Ruthy Perotto

; Zandonai, Cássio Luis

; Pincelli, Mariangela Pimentel

; Figueiredo, Rodrigo Cruvinel

; Bustamante, Cíntia Loss Sartori

; Norbin, Luiz Fernando

; Boschi, Emerson

; Lessa, Rafael

; Romano, Marcelo Pereira

; Miura, Mieko Cláudia

; Alencar Filho, Meton Soares de

; Dantas, Vicente Cés de Souza

; Barreto, Priscilla Alves

; Hernandes, Mauro Esteves

; Grion, Cintia Magalhães Carvalho

; Laranjeira, Alexandre Sanches

; Mezzaroba, Ana Luiza

; Bahl, Marina

; Starke, Ana Carolina

; Biondi, Rodrigo Santos

; Dal-Pizzol, Felipe

; Caser, Eliana Bernadete

; Thompson, Marlus Muri

; Padial, Andrea Allegrini

; Veiga, Viviane Cordeiro

; Leite, Rodrigo Thot

; Araújo, Gustavo

; Guimarães, Mário

; Martins, Priscilla de Aquino

; Lacerda, Fábio Holanda

; Hoffmann Filho, Conrado Roberto

; Melro, Livia

; Pacheco, Eduardo

; Ospina-Táscon, Gustavo Adolfo

; Ferreira, Juliana Carvalho

; Freires, Fabricio Jocundo Calado

; Machado, Flávia Ribeiro

; Cavalcanti, Alexandre Biasi

; Zampieri, Fernando Godinho

Critical Care Science

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2024, Volume 36 elocation e20240210en

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Contexto: Em estudos observacionais sobre a síndrome do desconforto respiratório agudo, sugeriu-se que a driving pressure é o principal fator de lesão pulmonar induzida por ventilador e de mortalidade. Não está claro se uma estratégia de limitação da driving pressure pode melhorar os desfechos clínicos. Objetivo: Descrever o protocolo e o plano de análise estatística que serão usados para testar se uma estratégia de limitação da driving pressure envolvendo a titulação da pressão positiva expiratória final de acordo com a melhor complacência respiratória e a redução do volume corrente é superior a uma estratégia padrão envolvendo o uso da tabela de pressão positiva expiratória final baixa do protocolo ARDSNet, em termos de aumento do número de dias sem ventilador em pacientes com síndrome do desconforto respiratório agudo devido à pneumonia adquirida na comunidade. Métodos: O estudo STAMINA (ventilator STrAtegy for coMmunIty acquired pNeumoniA) é randomizado, multicêntrico e aberto e compara uma estratégia de limitação da driving pressure com a tabela de pressão positiva expiratória final baixa do protocolo ARDSnet em pacientes com síndrome do desconforto respiratório agudo moderada a grave devido à pneumonia adquirida na comunidade internados em unidades de terapia intensiva. Esperamos recrutar 500 pacientes de 20 unidades de terapia intensiva brasileiras e duas colombianas. Eles serão randomizados para um grupo da estratégia de limitação da driving pressure ou para um grupo de estratégia padrão usando a tabela de pressão positiva expiratória final baixa do protocolo ARDSnet. No grupo da estratégia de limitação da driving pressure, a pressão positiva expiratória final será titulada de acordo com a melhor complacência do sistema respiratório. Desfechos: O desfecho primário é o número de dias sem ventilador em 28 dias. Os desfechos secundários são a mortalidade hospitalar e na unidade de terapia intensiva e a necessidade de terapias de resgate, como suporte de vida extracorpóreo, manobras de recrutamento e óxido nítrico inalado. Conclusão: O STAMINA foi projetado para fornecer evidências sobre se uma estratégia de limitação da driving pressure é superior à estratégia da tabela de pressão positiva expiratória final baixa do protocolo ARDSnet para aumentar o número de dias sem ventilador em 28 dias em pacientes com síndrome do desconforto respiratório agudo moderada a grave. Aqui, descrevemos a justificativa, o desenho e o status do estudo. Contexto sugeriuse sugeriu clínicos Objetivo ARDSNet Métodos ventilator pNeumoniA randomizado 50 2 colombianas Desfechos resgate extracorpóreo inalado Conclusão Aqui justificativa 5

ABSTRACT Background: Driving pressure has been suggested to be the main driver of ventilator-induced lung injury and mortality in observational studies of acute respiratory distress syndrome. Whether a driving pressure-limiting strategy can improve clinical outcomes is unclear. Objective: To describe the protocol and statistical analysis plan that will be used to test whether a driving pressure-limiting strategy including positive end-expiratory pressure titration according to the best respiratory compliance and reduction in tidal volume is superior to a standard strategy involving the use of the ARDSNet low-positive end-expiratory pressure table in terms of increasing the number of ventilator-free days in patients with acute respiratory distress syndrome due to community-acquired pneumonia. Methods: The ventilator STrAtegy for coMmunIty acquired pNeumoniA (STAMINA) study is a randomized, multicenter, open-label trial that compares a driving pressure-limiting strategy to the ARDSnet low-positive end-expiratory pressure table in patients with moderate-to-severe acute respiratory distress syndrome due to community-acquired pneumonia admitted to intensive care units. We expect to recruit 500 patients from 20 Brazilian and 2 Colombian intensive care units. They will be randomized to a driving pressure-limiting strategy group or to a standard strategy using the ARDSNet low-positive end-expiratory pressure table. In the driving pressure-limiting strategy group, positive end-expiratory pressure will be titrated according to the best respiratory system compliance. Outcomes: The primary outcome is the number of ventilator-free days within 28 days. The secondary outcomes are in-hospital and intensive care unit mortality and the need for rescue therapies such as extracorporeal life support, recruitment maneuvers and inhaled nitric oxide. Conclusion: STAMINA is designed to provide evidence on whether a driving pressure-limiting strategy is superior to the ARDSNet low-positive end-expiratory pressure table strategy for increasing the number of ventilator-free days within 28 days in patients with moderate-to-severe acute respiratory distress syndrome. Here, we describe the rationale, design and status of the trial. Background ventilatorinduced induced pressurelimiting limiting unclear Objective endexpiratory end expiratory lowpositive low ventilatorfree free communityacquired community Methods (STAMINA multicenter openlabel open label moderatetosevere moderate severe units 50 Outcomes inhospital hospital support oxide Conclusion Here rationale 5

https://doi.org/10.62675/2965-2774.20240210-en

Medicinal plants with popular names associated with manufactured drugs in Rio Grande do Sul state, Brazil state
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Higa, Karina Mayumi

; Ferreira Júnior, Washington Soares

; Albuquerque, Ulysses Paulino

; Soares, Geraldo Luiz Gonçalves

; Ritter, Mara Rejane

Rodriguésia

Journal Metrics
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2024, Volume 75 elocation e00572023

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Observou-se que as plantas medicinais utilizadas pela população do sul do Brasil têm sido referidas popularmente pelos nomes dos medicamentos industrializados. Este estudo visou encontrar uma ligação entre o uso de espécies de plantas medicinais com os nomes populares associados a medicamentos industrializados e o sistema biomédico atual. Foi criada uma base de dados sobre estas plantas medicinais com base em 34 estudos etnobotânicos realizados no estado do Rio Grande do Sul, Brasil, e foram buscadas informações químicas e farmacológicas a partir de uma base de dados de artigos científicos, e cruzadas para determinar se as informações populares estavam correlacionadas. Foram encontradas 31 espécies com um total de 25 nomes populares de medicamentos industrializados diferentes. O maior número de nomes populares de medicamentos industrializados foi para Alternanthera brasiliana com oito nomes, seguido de Achillea millefolium com seis. Verificou-se que a indicação terapêutica das espécies utilizadas nas fórmulas industrializadas era diferente das indicações de uso popular. No entanto, a indicação terapêutica de ambas foram correlacionadas para distúrbios digestivos, bem como para as espécies designadas popularmente por fitoterápicos. A adoção cultural de nomes populares pode ser influenciada pelo sistema biomédico e pelo fluxo de conhecimento decorrente da medicina convencional em direção à medicina popular. Observouse Observou atual 3 Sul científicos 2 diferentes seis Verificouse Verificou popular entanto digestivos fitoterápicos

Abstract Medicinal plants used by the population in southern Brazil have been observed to be popularly referred to by the names of manufactured drugs. This study aimed to find a connection between the use of medicinal plant species with popular names associated with manufactured drugs and the actual biomedical system. A database regarding such medicinal plants was established based on thirty-four ethnobotanical studies undertaken in the state of Rio Grande do Sul, Brazil, and chemical and pharmacological information was collected from a scientific article database and crossed referenced to determine whether folk information was correlated. Thirty-one species with a total of twenty-five different popular names of manufactured drugs were found. The greatest number of popular names of manufactured drugs was for Alternanthera brasiliana with eight names, followed by Achillea millefolium with six. The therapeutic indication of the species used in the manufactured formulas was found to differ from the indications of popular use. However, the therapeutic indication of both were correlated for digestive disorders, as well as for popularly named phytotherapic species. Cultural adoption of popular names may be influenced by the biomedical system and the flow of knowledge arising from conventional medicine toward popular medicine. thirtyfour thirty four Sul Thirtyone Thirty one twentyfive twenty five six However disorders

https://doi.org/10.1590/2175-7860202475022

Human papillomavirus in women infected with human immunodeficiency virus: association with viral load and lymphocyte count virus
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Morais, Ana Cléa Cutrim Diniz de

; Ferreira, Alice de Sá

; Barbosa, Carla Déa Trindade

; Lima, Maria Fernanda Bezerra

; Fook, Karina Donato

; Carvalho, Mônika Machado de

; Muniz, Alessandra Costa de Sales

; Araújo, Deborah Rocha de

; Monteiro, Pablo de Matos

; Araújo, Maria José Abigail Mendes

; Monteiro, Sally Cristina Moutinho

; Lopes, Fernanda Ferreira

Revista do Instituto de Medicina Tropical de São Paulo

Journal Metrics
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2024, Volume 66 elocation e36

Abstract: En | Text: En | PDF: En

ABSTRACT Women living with human immunodeficiency virus are at an increased risk of developing cancers related to human papillomavirus (HPV). Thus, it is important to combine clinical assessments, serological screening, and HPV data for planning prevention policies. This study aimed to identify HPV and its specific types in the cervical, anal, and oral mucosa of HIV-seropositive women, associating it with viral load and lymphocyte count. Sociodemographic characteristics, health data (CD4+ and CD8+ T cell counts and viral load), and biological samples (cervical, anal, and oral) were collected from 86 HIV-positive women undergoing antiretroviral therapy. Data were classified according to the presence or absence of HPV-DNA, HPV-DNA presence at one or more anatomic sites, and level of oncogenic risk, considering low- and high-risk oncogenic HPV-DNA groups. The presence of HPV in the cervicovaginal site was 65.9%, 63.8% in anal canal, and 4.2% in oral mucosa. A viral load ≥75 HIV copies/mL was associated with the presence of HPV-DNA. There was an association between viral load and the low-risk HPV or high-risk HPV groups. We found a high prevalence of HPV infection in HIV-seropositive women, particularly in the cervical and anal mucosa, with viral load ≥75 HIV copies/mL being associated with HPV-DNA presence. HPV. . (HPV) Thus assessments screening policies HIVseropositive seropositive count characteristics CD4+ CD4 CD (CD4 CD8 load, , load) (cervical 8 HIVpositive positive therapy HPVDNA, HPVDNA DNA, DNA sites low highrisk groups 659 65 9 65.9% 638 63 63.8 canal 42 4 2 4.2 75 ≥7 copiesmL copies mL HPVDNA. DNA. lowrisk (HPV (CD 6 65.9 63. 4. 7 ≥ 65.

https://doi.org/10.1590/s1678-9946202466036

10.

Immunogenicity of COVID-19 adsorbed inactivated vaccine (CoronaVac) and additional doses of mRNA BNT162b2 vaccine in immunocompromised adults compared with immunocompetent persons COVID19 COVID 19 COVID-1 CoronaVac (CoronaVac BNTb BNT b BNT162b COVID1 1 COVID-
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Ibrahim, Karim Yaqub

; Moreira, Raquel Megale

; Santos, Carolina Ferreira dos

; Strabelli, Tânia Mara Varejão

; Belizário, Juliana de Cássia

; Pinto, Maria Isabel de Moraes

; Marinho, Ana Karolina Barreto Berselli

; Pereira, Juliana Marquezi

; Mello, Liliane Saraiva de

; Ando, Mauricio Cesar

; Silva, Vitor Gabriel Lopes da

; Sato, Paula Keiko

; Lima, Marcos Alves de

; França, João Italo Dias

; Loch, Ana Paula

; Miyaji, Karina Takesaki

; Infante, Vanessa

; Precioso, Alexander Roberto

; Sartori, Ana Marli Christovam

Revista do Instituto de Medicina Tropical de São Paulo

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2024, Volume 66 elocation e24

Abstract: En | Text: En | PDF: En

ABSTRACT Inactivated COVID-19 vaccines data in immunocompromised individuals are scarce. This trial assessed the immunogenicity of two CoronaVac doses and additional BNT162b2 mRNA vaccine doses in immunocompromised (IC) and immunocompetent (H) individuals. Adults with solid organ transplant (SOT), hematopoietic stem cell transplant, cancer, inborn immunity errors or rheumatic diseases were included in the IC group. Immunocompetent adults were used as control group for comparison. Participants received two CoronaVac doses within a 28-day interval. IC received two additional BNT162b2 doses and H received a third BNT162b2 dose (booster). Blood samples were collected at baseline, 28 days after each dose, pre-booster and at the trial end. We used three serological tests to detect antibodies to SARS-CoV-2 nucleocapsid (N), trimeric spike (S), and receptor binding domain (RBD). Outcomes included seroconversion rates (SCR), geometric mean titers (GMT) and GMT ratio (GMTR). A total of 241 IC and 100 H adults participated in the study. After two CoronaVac doses, IC had lower SCR than H: anti-N, 33.3% vs 79%; anti-S, 33.8% vs 86%, and anti-RBD, 48.5% vs 85%, respectively. IC also showed lower GMT than H: anti-N, 2.3 vs 15.1; anti-S, 58.8 vs 213.2 BAU/mL; and anti-RBD, 22.4 vs 168.0 U/mL, respectively. After the 3rd and 4th BNT162b2 doses, IC had significant anti-S and anti-RBD seroconversion, but still lower than H after the 3rd dose. After boosting, GMT increased in IC, but remained lower than in the H group. CoronaVac two-dose schedule immunogenicity was lower in IC than in H. BNT162b2 heterologous booster enhanced immune response in both groups. COVID19 COVID 19 COVID-1 scarce BNTb BNT b BNT162b (IC (H SOT, SOT , (SOT) cancer comparison 28day day interval booster. . (booster) baseline 2 prebooster pre end SARSCoV2 SARSCoV SARS CoV SARS-CoV- N, N (N) S, S (S) RBD. RBD (RBD) SCR, (SCR) (GMT GMTR. GMTR (GMTR) 24 10 study antiN, antiN anti anti-N 333 33 3 33.3 79% 79 antiS, antiS 338 8 33.8 86 86% antiRBD, antiRBD RBD, 485 48 5 48.5 85 85% respectively 23 2. 15.1 151 15 1 588 58 58. 2132 213 213. BAU/mL BAUmL BAU mL 224 22 4 22. 1680 168 0 168. UmL U U/mL rd th boosting twodose groups COVID1 COVID- (SOT (booster SARS-CoV (N (S (RBD (SCR (GMTR 33. 7 48. 15. 21 16

https://doi.org/10.1590/s1678-9946202466024

11.

Effect of thyme essential oil on the properties of poly (butylene adipate-co-terephthalate)(PBAT) butylene adipatecoterephthalatePBAT adipate co terephthalate PBAT adipate-co-terephthalate)(PBAT
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Luna, Pâmela Barcelar Ferreira Gomes da Silva de

; Caetano, Viviane Fonseca

; Andrade, Michelle Félix de

; Silva, Ivo Diego de Lima

; Araújo, Tiago Lopes de

; Souza, Karina Carvalho de

; Almeida, Yêda Medeiros Bastos de

; Vinhas, Glória Maria

Polímeros

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2024, Volume 34 N. 1 elocation e20240005

Abstract: En | Text: En | PDF: En

Abstract In this study, thyme essential oil was added to poly (butylene adipate-co-terephthalate) (PBAT) films in a variety of compositions (0, 1, 2, 5, 10, 15, and 20% w/w), and the effect of the essential oil on the PBAT's characteristics was evaluated. The films were produced using the casting technique. Thyme essential oil (EO) was evaluated by mid-infrared, gas chromatography-mass spectrometer, and antimicrobial activity. The films were evaluated by mid-infrared, mechanical, and thermal tests. The results demonstrated that EO has a higher concentration of o-cymene and antimicrobial activity against the bacteria Escherichia coli and Staphylococcus aureus. The films were analyzed for their mechanical and thermal properties according to the compositions tested. The films have shown promise for use as active packaging. study butylene adipatecoterephthalate adipate co terephthalate adipate-co-terephthalate PBAT (PBAT 0, 0 (0 1 2 5 10 15 20 w/w, ww w/w , w w/w) PBATs s technique (EO midinfrared, midinfrared mid infrared, infrared mid-infrared chromatographymass chromatography mass spectrometer tests ocymene o cymene aureus tested packaging (

https://doi.org/10.1590/0104-1428.20230009

12.

Percepção de cuidadores de pré-escolares com TEA sobre seu comportamento e desempenho ocupacional durante a pandemia da COVID-19 préescolares pré escolares COVID19 COVID 19 COVID-1 COVID1 1 COVID-
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Silva, Maene Pinheiro

; Souza, Rosangela Gomes da Mota de

; Oliveira, Karina Ferreira de

; Cardoso, Ana Amélia

; Magalhães, Lívia de Castro

Cadernos Brasileiros de Terapia Ocupacional

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2024, Volume 32 elocation e3590

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução Crianças com Transtorno do Espectro Autista (TEA) podem apresentar questões comportamentais, no processamento sensorial, na cognição e na linguagem, que afetam seu desempenho ocupacional, necessitando de acesso a serviços escolares, terapêuticos e de saúde. O acesso a esses serviços esteve restrito durante a pandemia de COVID-19, tornando essa população particularmente ainda mais vulnerável às restrições sociais impostas à época. Objetivo Descrever a percepção dos pais cuidadores de pré-escolares com TEA acerca do comportamento e desempenho ocupacional de seus filhos durante a pandemia da COVID-19. Método Estudo transversal, descritivo, quantitativo e qualitativo baseado em entrevistas com 60 cuidadores de pré-escolares com TEA. Os participantes responderam à seguinte pergunta: Você está notando alguma diferença no comportamento e desempenho da criança durante a pandemia? Para caracterização das crianças, foram utilizados o Sistema de Classificação de Funcionalidade no Autismo: Comunicação Social (ACSF:SC), o Inventário de Avaliação Pediátrica de Incapacidade - Teste Adaptativo de Computador (PEDI-CAT) e o Perfil Sensorial 2 (SP-2). Todas as entrevistas foram anotadas e 15 delas foram gravadas e transcritas. O material foi submetido à análise temática de conteúdo. Resultados Foram entrevistadas 43 mães, 15 casais e dois pais de crianças com TEA. Das 60 crianças, 46 (76,7%) eram meninos, com idade de 3 a 5 anos (53,6 ±10,18 meses). Os cuidadores perceberam mudanças no comportamento e desempenho ocupacional, com prevalência de relatos de piora. Houve aumento nas estereotipias, rigidez e hiperfoco, bem como menor engajamento nas atividades cotidianas. A presença dos cuidadores beneficiou algumas crianças, mas há relato de estresse, especialmente por parte das mães. Conclusão Houve variação nos relatos, com maior tendência à piora no comportamento e desempenho ocupacional das crianças com TEA. (TEA comportamentais sensorial linguagem escolares saúde COVID19, COVID19 COVID 19, 19 COVID-19 época préescolares pré COVID19. 19. transversal descritivo 6 pergunta Autismo ACSFSC, ACSFSC ACSF SC , (ACSF:SC) PEDICAT PEDI CAT (PEDI-CAT SP2. SP2 SP . (SP-2) 1 transcritas conteúdo 4 mães 76,7% 767 76 7 (76,7% meninos 53,6 536 53 (53, 1018 10 18 ±10,1 meses. meses meses) estereotipias hiperfoco cotidianas estresse COVID1 COVID-1 (ACSF:SC (SP-2 76,7 (76,7 53, (53 101 ±10, COVID- (SP- 76, (76, (5 ±10 (SP (76 ( ±1 (7 ±

Abstract Introduction Children with Autism Spectrum Disorder (ASD) face behavioral, sensory processing, cognitive, and language challenges that affect their ability to perform activities of daily living (ADL) and necessitate access to educational, therapeutic, and health services. The COVID-19 pandemic limited access to these essential services, exacerbating the challenges faced by this vulnerable population due to imposed social distancing measures. Objective To explore the perceptions of parent caregivers of preschoolers with ASD regarding their children’s behavior and performance in ADL during the COVID-19 pandemic. Method This cross-sectional, descriptive study utilized both quantitative and qualitative approaches, interviewing 60 caregivers of preschoolers with ASD. Participants were asked about any observed changes in their child’s behavior and ability to engage in ADL during the pandemic. Child characterization involved the Autism Classification System of Functioning: Social Communication (ACSF:SC), the Pediatric Evaluation of Disability Inventory - Computer Adaptive Test (PEDI-CAT), and the Sensory Profile 2 (SP-2). Interviews were documented, with 15 recorded and transcribed for thematic content analysis. Results Participants included 43 mothers, 15 couples, and two fathers, totaling 60 children, of whom 46 (76.7%) were boys aged between 3 and 5 years (mean age 53.6 ±10.18 months). Caregivers reported changes in behavior and performance in ADL, predominantly noting deterioration. Increases in stereotypic behaviors, rigidity, and hyperfocus were observed, along with decreased participation in ADL. While the presence of caregivers benefited some children, it also led to reported stress, particularly among mothers. Conclusion The study found a predominant trend of deteriorating behavior and performance in ADL among children with ASD during the pandemic, based on caregiver reports. (ASD behavioral processing cognitive (ADL educational therapeutic services COVID19 COVID 19 COVID-1 measures childrens s crosssectional, crosssectional cross sectional, sectional cross-sectional approaches 6 childs child Functioning ACSFSC, ACSFSC ACSF SC , (ACSF:SC) PEDICAT, PEDICAT PEDI CAT (PEDI-CAT) SP2. SP2 SP . (SP-2) documented 1 analysis 4 mothers couples fathers 76.7% 767 76 7 (76.7% mean 536 53 53. 1018 10 18 ±10.1 months. months months) deterioration behaviors rigidity stress reports COVID1 COVID- (ACSF:SC (PEDI-CAT (SP-2 76.7 (76.7 101 ±10. (SP- 76. (76. ±10 (SP (76 ±1 (7 ± (

https://doi.org/10.1590/2526-8910.ctoao275935901

13.

Average direct cost of peripherally inserted central catheterization by nurses in hospitalized patients: a cost estimate patients
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Zandonadi, Maithê Gomes Lima

; Nogueira, Danielly Negrão Guassú

; Nascimento, Amanda Salles Margatho do

; Ruiz, Paula Buck de Oliveira

; Ferreira, Natália Marciano de Araújo

; Giroti, Suellen Karina de Oliveira

; Pieri, Flávia Meneguetti

einstein (São Paulo)

Journal Metrics
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2024, Volume 22 elocation eGS0982

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: This study aimed to estimate the direct costs of peripherally inserted central catheterization by nurses for hospitalized patients. Methods: A cost estimation study using a quantitative approach was conducted in a public teaching hospital in northern Paraná to calculate the direct costs of peripherally inserted central catheterization. The population included all medical records of patients between 15 and 99 years of age who were hospitalized and underwent peripherally inserted central catheterization by nurses between January 1, 2019, and December 31, 2021, totaling 664 insertions. The sample comprised 631 insertions. Results: The catheter kits (epicutaneous catheter + introducer + angulators) corresponded to the items with the highest unit costs and the greatest impact on the composition of costs. The cost of peripherally inserted central catheterization was US$ 217.14 (SD=75.21), with the cost of materials and staff's labor being US$ 195.39 (SD=74.15) and US$ 20.00 (SD=2.22), respectively. Conclusion: Materials represented the highest cost, which was explained by the high unit cost of catheters and kits used in echocardiography, followed by the staff's labor costs. The estimated average direct cost allowed for financial visibility of the inputs used. The key challenge is promoting lasting changes in the behavior of managers who carry out administrative functions in healthcare institutions, where proper budget management directly affects the allocative efficiency of resources and the quality of care. Objective Methods 1 9 2019 31 2021 66 insertions 63 Results epicutaneous angulators US 21714 217 14 217.1 SD=75.21, SD7521 SD SD=75.21 , 75 21 (SD=75.21) staffs staff s 19539 195 39 195.3 SD=74.15 SD7415 74 (SD=74.15 2000 20 00 20.0 SD=2.22, SD222 SD=2.22 2 22 (SD=2.22) respectively Conclusion echocardiography institutions care 201 3 202 6 2171 217. SD752 SD=75.2 7 (SD=75.21 1953 19 195. SD=74.1 SD741 (SD=74.1 200 0 20. SD22 SD=2.2 (SD=2.22 SD75 SD=75. (SD=75.2 SD=74. SD74 (SD=74. SD2 SD=2. (SD=2.2 SD7 SD=75 (SD=75. SD=74 (SD=74 SD=2 (SD=2. SD=7 (SD=75 (SD=7 SD= (SD=2 (SD= (SD

https://doi.org/10.31744/einstein_journal/2024gs0982

14.

Can infrared thermography replace other methods of assessing orofacial pain intensity? Systematic review intensity
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Americano, Julia Pereira

; Pires, Sofia Melo

; Ferreira, Luciano Ambrósio

; Devito, Karina Lopes

BrJP

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2024, Volume 7 elocation e20240049

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO JUSTIFICATIVA E OBJETIVOS: A mensuração da dor é complexa devido aos seus vários componentes, incluindo o aspecto subjetivo. É extremamente importante estabelecer um método eficaz e seguro para avaliar a dor orofacial (DOF). O objetivo deste estudo foi realizar uma revisão sistemática para verificar se a termografia infravermelha (TI) pode ser usada como substituta de outros métodos de avaliação da intensidade da DOF neuropática ou musculoesquelética. CONTEÚDO: Foram pesquisados cinco bancos de dados: Pubmed, Scielo, Web of Science, Scopus e Cochrane. A questão PECO foi usada para orientar a definição dos critérios de elegibilidade usados para selecionar os artigos. O risco de viés foi analisado usando a escala Joanna Briggs. Cinco estudos atenderam aos critérios de elegibilidade. Dos cinco estudos elegíveis, quatro relataram uma associação entre a intensidade da DOF e a temperatura. Desses, um artigo mostrou que os pacientes com distúrbios temporomandibulares (DTM) e dor apresentaram um aumento na temperatura quando comparados com indivíduos sem dor. Os outros três artigos mostraram uma diminuição da temperatura com o aumento da intensidade da dor. Em apenas um estudo a intensidade da dor não foi significativamente associada à temperatura. CONCLUSÃO: A TI não substitui outros métodos de avaliação da intensidade da dor, mas é um importante aliado para complementar os procedimentos diagnósticos. São necessárias investigações adicionais para encontrar um método padronizado de obtenção e análise de imagens infravermelhas orofaciais. OBJETIVOS componentes subjetivo DOF. . (DOF) (TI musculoesquelética CONTEÚDO dados Pubmed Scielo Science Cochrane Briggs elegíveis Desses DTM (DTM CONCLUSÃO diagnósticos orofaciais (DOF

ABSTRACT BACKGROUND AND OBJECTIVES: Measuring pain is complex due to its various components, including the subjective aspect. Establishing an effective and safe method for assessing orofacial pain (OFP) is extremely important. The objective of this study was to conduct a systematic review to verify whether Infrared Thermography (IT) can be used as a substitute for other methods of evaluating the intensity of neuropathic or musculoskeletal OFP. CONTENTS: Five databases were searched: Pubmed, Scielo, Web of Science, Scopus, and Cochrane. The PECO question was used to guide the definition of eligibility criteria used to select the articles. The risk of bias was analyzed using the Joanna Briggs scale. Five studies met the eligibility criteria. Of the five eligible studies, four reported an association between orofacial pain intensity and temperature. Of these, one article showed that patients with temporomandibular disorders (TMD) and pain showed an increase in temperature when compared with individuals without pain. The other three articles showed a decrease in temperature with increasing pain intensity. In only one study pain intensity was not significantly associated with temperature. CONCLUSION: IT does not replace other pain intensity assessment methods, but it is an important ally for complementing diagnostic procedures. Additional investigations are necessary to find a standardized method for obtaining and analyzing orofacial infrared images. OBJECTIVES components aspect OFP (OFP (IT CONTENTS searched Pubmed Scielo Science Scopus Cochrane scale these TMD (TMD CONCLUSION procedures images

https://doi.org/10.5935/2595-0118.20240049-en

15.

Recommendations on cutaneous and hematological manifestations of Sjögren’s disease by the Brazilian Society of Rheumatology Sjögrens Sjögren s
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Pugliesi, Alisson

; Egypto, Danielle Christinne Soares do

; Duffles, Guilherme

; Cantali, Diego Ustárroz

; Pasoto, Sandra Gofinet

; Oliveira, Fabiola Reis

; Valim, Valeria

; Lopes, Maria Lucia Lemos

; Miyamoto, Samira Tatiyama

; Fernandes, Marilena Leal Mesquita Silvestre

; Fialho, Sonia Cristina de Magalhães Souza

; Pinheiro, Aysa César

; Santos, Laura Caldas dos

; Appenzeller, Simone

; Ribeiro, Sandra Lucia Euzébio

; Libório-Kimura, Tatiana Nayara

; Santos, Maria Carmen Lopes Ferreira Silva

; Gennari, Juliana D´Agostino

; Pernanbuco, Roberta

; Capobiano, Karina Gatz

; Civile, Vinicius Tassoni

; Pinto, Ana Carolina Pereira Nunes

; Rocha-Filho, César Ramos

; Rocha, Aline Pereira da

; Trevisani, Virginia Fernandes Moça

Advances in Rheumatology

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2024, Volume 64 elocation 51

Abstract: En | Text: En | PDF: En

Abstract Sjogren’s disease (SjD) is an autoimmune disease that is characterized not only by the sicca symptoms it causes but also by its systemic nature, which is capable of several and not yet fully understood extraglandular manifestations. To gain a clearer understanding of these manifestations as well as a better practical approach, a panel of experts from the Brazilian Society of Rheumatology conducted a systematic review and meta-analysis on the identification of epidemiologic and clinical features of the extraglandular manifestations present in ESSDAI (EULAR Sjogren´s syndrome disease activity index), followed by a voting panel with recommendations for clinical practice. This publication is complementary to others already published and covers cutaneous and hematological manifestations, with prevalence data generated by a meta-analysis of 13 clinical or laboratory manifestations and 6 clinical management recommendations. Sjogrens Sjogren s SjD (SjD nature approach metaanalysis meta analysis EULAR index, index , index) practice 1

https://doi.org/10.1186/s42358-024-00391-x

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