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Emotion regulation and executive functions in young and older Brazilian adults
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Ferreira Bueno, Luisa Beatriz

; Marques de Pinho, Karine

; Satler, Corina Elizabeth

Revista Latinoamericana de Psicología

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dec 2024, Volume 56 Pages 129 - 137

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Introducción/objetivo: El proceso de envejecimiento saludable implica cambios en las funciones neurobiológicas a varios niveles y se asocia con un ligero deterioro en diversos dominios cognitivos, como las funciones ejecutivas (FE), así como con una mejora de las habilidades emocionales. El objetivo de este estudio es comparar el uso de estrategias de regulación emocional (RE) en jóvenes y adultos mayores y explorar la asociación entre habilidades de RE y FE entre los grupos etarios. Método: Participaron 40 jóvenes entre 18 y 39 años (50 % mujeres) y 40 adultos mayores de > 60 años (50 % mujeres), todos residentes en el Distrito Federal (Brasil). Se administraron las pruebas de Fluidez Verbal Fonológica (FAS), semántica y de cambio (animales y frutas) y de acciones, junto al Test de Stroop. Resultados: Hubo una correlación estadísticamente significativa entre la estrategia de reevaluación cognitiva (RC) y las pruebas de fluidez verbal semántica y de cambio en jóvenes y entre la estrategia de RC y la prueba FAS y el Test Stroop en adultos mayores. Eso es, el desempeño ejecutivo mostró relación directa con la RE en ambos grupos, con mayor uso de la RC por parte de los adultos mayores. Conclusiones: Los resultados de este estudio resaltan la pertinencia de continuar investigando la relación entre estas habilidades y analizar con mayor profundidad sus alteraciones durante la edad adulta y el proceso de envejecimiento.

Abstract Introduction/objective: The healthy aging process involves changes in neurobiological functions at various levels and is associated with a slight impairment in various cognitive domains, such as executive functions (EF), as well as the enhancement of emotional skills. The objective of this study was to compare the use of emotion regulation (ER) strategies in young adults (YA) and older adults (OA) and explore the association between ER skills and EF between age groups. Method: Participants were 40 YA between 18 and 39 years of age (50% women) and 40 OA > 60 years old (50% women), residents in the Federal District, Brazil. Phonological Verbal Fluency (FAS), semantic and switching (animals and fruits) and action tests were administered, along with the Stroop Test. Results: There was a statistically significant correlation of the Cognitive Reappraisal (CR) strategy and both semantic and switching verbal fluency tests in YA, and between the CR strategy and the FAS test and the Stroop Test in OA. That is, executive performance showed a direct relationship with ER in both groups, with greater use of cognitive reappraisal by older adults. Conclusions: The results of this study highlight the relevance of continuing to investigate the relationship between these abilities and analysing in greater depth their alterations during the aging process.

https://doi.org/10.14349/rlp.2024.v56.13

Bone regeneration by a bone substitute biomaterial containing hydroxyapatite, chitosan, xanthan and graphene oxide supplemented with conditioned medium from mesenchymal stem cells
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Rocha, Daniel N

; López, David GM

; Ferreira, José RM

; Silva, Marcelo HP

; Filgueiras, Isabela AAAP

; Alves, Bruno F

; Almeida, Bruno M

; Kotaka, Jatiana

; Buss, Leonardo F

; Magnabosco, José L

; Teixeira, Marcelo L

; Mariano, Éric D

; Cationi, Mariáh H

; Bosco, Isadora

; Nascimento, Marvin

; Canal, Raul

; Neves, José G

; Aloise, Antonio C

; Martínez, Elizabeth F

; Holliday, Lexie S

; Pelegrine, André A

Acta Odontológica Latinoamericana

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sep 2024, Volume 37 N. 2 Pages 151 - 161

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Este estudo analisou um biomaterial substituto ósseo recentemente desenvolvido feito de óxido de quitosana- xantana-hidroxiapatita-grafeno (CXHAG). As partículas CXHAG observaram caracterização estrutural e morfológica in vitro. Foi testado in vivo, com ou sem meio condicionado osteogênico de células-tronco mesenquimais. Objetivo O objetivo deste estudo foi determinar se o novo biomaterial CXHAG, suplementado com meio condicionado de células-tronco mesenquimais, poderia ser útil para a regeneração óssea. Materiais e Método Para o estudo in vitro, as células foram incubadas com 20mg de grânulos de CXHAG por 24 horas e foi realizado ensaio de MTT para verificar a citotoxicidade. Para o estudo in vivo, foram criados defeitos ósseos de tamanho crítico na calvária em vinte e cinco ratos. Um animal teve o defeito não preenchido (Grupo Controle – GC) e foi eutanasiado após 42 dias. Doze ratos receberam as partículas CXHAG (Grupo 1 – G1) e os outros doze receberam as partículas CXHAG suplementadas com o meio condicionado (Grupo 2 – G2). Todos os enxertos G1/G2 foram cobertos com membrana CXHAG. Os animais do G1/G2 foram eutanasiados após 14 dias (T1) ou 42 dias (T2). Os espécimes foram processados e avaliados histologicamente. Resultados A análise SEM das partículas CXHAG mostrou grânulos de 300-400μm, com superfície áspera e irregular. Eles não foram citotóxicos para células-tronco da polpa dentária in vitro. As amostras CG mostraram tecido conjuntivo imaturo frouxo e nenhuma formação óssea no centro do defeito. G1 e G2 apresentaram partículas remanescentes de biomateriais em ambos os momentos, mas apenas G2 apresentou formação óssea no centro do defeito. Conclusões O meio condicionado teve repercussões positivas na regeneração óssea em defeitos críticos de calvária de ratos quando associado ao novo biomaterial substituto ósseo.

ABSTRACT This study analyzed a recently developed bone substitute biomaterial made of chitosan-xanthanhydroxyapatite- graphene oxide (CXHAG). The CXHAG particles underwent in vitro structural and morphological characterization, and in vivo testing with or without osteogenic conditioned medium from mesenchymal stem cells. Aim The aim of this study was to determine whether the CXHAG novel biomaterial, supplemented with conditioned medium from mesenchymal stem cells, could be useful for bone regeneration. Materials and Method For the in vitro study, cells were incubated with 20mg of CXHAG granules for 24 hours and a MTT assay was performed to tests for cytotoxicity. For the in vivo study, critical size calvarial bone defects were created in twenty-five rats. One animal had the defect unfilled (Control Group–CG) and was euthanized after 42 days. Twelve rats received the CXHAG particles (Group 1–G1) and the other twelve received the CXHAG particles supplemented with the conditioned medium (Group 2–G2). All G1/G2 grafts were covered with a CXHAG membrane. G1/G2 animals were euthanized after 14 days (T1) or 42 days (T2). The specimens were processed and histologically evaluated. Results SEM analysis of the CXHAG particles showed granules of 300-400μm, with a rough irregular surface. They were not cytotoxic to dental pulp stem cells in vitro. The CG specimen showed loose immature connective tissue and no bone formation at the center of the defect. G1 and G2 presented remnant biomaterial particles at both time points, but only G2 had bone formation at the center of the defect. Conclusions The conditioned medium had a positive effect on bone regeneration in rat calvarial critical size defects when associated with the novel bone substitute biomaterial.

https://doi.org/10.54589/aol.37/2/151

Fatores contextuais do desempenho do atendimento odontológico para gestantes na Atenção Básica entre municípios baianos
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Silva Junior, Manoelito Ferreira

; Saraiva, Amanda Cristina Laranjeira

; Matos, Patrícia Elizabeth Souza

Saúde em Debate

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2024, Volume 48 N. 140 elocation e8844

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Este estudo objetivou analisar os fatores contextuais do desempenho do atendimento odontológico para gestantes na Atenção Básica entre municípios baianos. A série temporal utilizou dados secundários dos 417 municípios, entre 2018 e 2022. O desfecho foi a meta do indicador de proporção de gestantes com atendimento odontológico por município: insuficiente (<60,0%) ou suficiente (≥60,0%). As variáveis contextuais foram: fatores sociodemográficos (Porte Populacional, Índice de Desenvolvimento Humano Municipal, Produto Interno Bruto municipal per capita – PIB, Índice de Gini da renda domiciliar per capita, Índice de Vulnerabilidade Social e Núcleos Regionais de Saúde) e serviço de saúde (Cobertura de Estratégia Saúde da Família – ESF e de Saúde Bucal). Realizou-se regressão de Poisson uni e multivariada (p<0,05). No último quadrimestre de cada ano: 2,9% (2018), 2,4% (2019), 5,3% (2020), 37,2% (2021) e 71,2% (2022) dos municípios atingiram a meta. No terceiro quadrimestre de 2021, os municípios com menor PIB, e em 2021 e 2022, com maior cobertura de ESF, apresentaram maior chance de atingir a meta. Conclui-se que houve aumento da proporção de atendimento odontológico para gestante ao longo dos anos entre os municípios baianos e atingir a meta foi associado a fatores sociodemográficos e de serviço de saúde.

https://doi.org/10.1590/2358-289820241408844p

SIMPLESMENTE MÃES: CONSTRUÇÃO COMPARTILHADA DE TECNOLOGIAS SOBRE PRÉ-NATAL DE MULHERES COM DEFICIÊNCIA VISUAL MÃES PRÉNATAL PRÉ NATAL
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Carvalho, Geovana de Jesus Ferreira de

; Tavares, Jheise Sandy da Cruz

; Silva, Nayara Costa Modesto da

; Nascimento, Marcia Helena Machado

; Teixeira, Elizabeth

; Araujo, Sílvia Teresa Carvalho de

; Costa, Fernanda de Nazaré Almeida

Cogitare Enfermagem

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2024, Volume 29 elocation e92082

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: Desenvolver tecnologias educacionais sobre pré-natal com e para mulheres deficientes visuais. Método: Estudo metodológico com interface participativa e abordagem qualitativa. Realizado em uma Unidade Técnica Especializada no município de Belém, Pará, Brasil. A produção de dados ocorreu entre agosto e setembro de 2021 com seis mulheres. Utilizou-se o DOSVOX como recurso de comunicação para que as participantes respondessem quatro instrumentos com vistas ao desenvolvimento das tecnologias. A análise foi de conteúdo temático. Resultados: As mulheres com deficiência visual querem respeito à sua autonomia, inclusão e informação dos profissionais. As tecnologias produzidas apontam as demandas específicas de mulheres com deficiência visual e a importância de preservar a autonomia durante a realização do pré-natal. Conclusão: Tecnologias produzidas de forma participativa apontam perspectivas e necessidades específicas das mulheres sobre o pré-natal e poderão subsidiar tanto o agir dos enfermeiros nas consultas como favorecer mulheres com deficiência visual durante o pré-natal. Objetivo prénatal pré natal visuais Método qualitativa Belém Pará Brasil 202 Utilizouse Utilizou se temático Resultados profissionais prénatal. natal. Conclusão 20 2

ABSTRACT Objective: To develop educational technologies on prenatal care with and for visually impaired women. Method: A methodological study with a participatory interface and qualitative approach. It was carried out at a Specialized Technical Unit in the municipality of Belém, Pará, Brazil. Data production took place between August and September 2021 with six women. DOSVOX was used as a communication resource for the participants to answer four instruments with a view to developing the technologies. The analysis was of the thematic content type. Results: Women with visual impairment want respect for their autonomy, inclusion, and information from the professionals. The technologies produced point to the specific demands of visually impaired women and to the importance of preserving autonomy during prenatal care. Conclusion: Technologies produced in a participatory way point out women’s specific perspectives and needs regarding prenatal care and may support both the nurses’ actions in consultations and favor women with visual impairment during prenatal care. Objective Method approach Belém Pará Brazil 202 type Results inclusion professionals Conclusion womens s nurses 20 2

RESUMEN Objetivo: Desarrollar tecnologías educativas sobre el control prenatal con y para mujeres con discapacidad visual. Método: Estudio metodológico con interfaz participativa y enfoque cualitativo. Realizado en una Unidad Técnica Especializada de la ciudad de Belém, Pará, Brasil. La producción de datos se realizó entre agosto y septiembre de 2021 con seis mujeres. Se utilizó DOSVOX como recurso de comunicación para que las participantes respondieran a cuatro instrumentos a fin de desarrollar las tecnologías. El análisis fue de contenido temático. Resultados: Las mujeres con discapacidad visual quieren que se respete su autonomía, inclusión e información por parte de los profesionales. Las tecnologías creadas ponen de manifiesto las demandas específicas de las mujeres con discapacidad visual y la importancia de preservar la autonomía durante el control prenatal. Conclusión: Las tecnologías creadas de manera participativa señalan las perspectivas y necesidades específicas de las mujeres con respecto al cuidado prenatal y pueden ayudar a los enfermeros en las consultas y a las mujeres con discapacidad visual durante el control prenatal. Objetivo Método cualitativo Belém Pará Brasil 202 temático Resultados profesionales Conclusión 20 2

https://doi.org/10.1590/ce.v29i0.92082

Estudo descritivo dos eventos supostamente atribuíveis à vacinação contra a mpox no Brasil em 2023
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Silva, Roberta Mendes Abreu

; Kobayashi, Carla Dinamerica

; Martins, Adriano Ferreira

; Araújo, Ana Catarina de Melo

; Andrade, Paulo Henrique Santos

; Nóbrega, Martha Elizabeth Brasil da

; Cabral, Cibelle Mendes

; Moraes, Monica Brauner de

; Cardoso, Felipe Daniel

; Victer, Thayssa Neiva da Fonseca

; Krummenauer, Amanda

; Soares, Rodrigo Otávio Pereira Sayago

; Fernandes, Eder Gatti

; Percio, Jadher

Cadernos de Saúde Pública

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2024, Volume 40 N. 10 elocation e00006624

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen: El objetivo fue describir las acciones de vigilancia y seguridad de la vacuna contra mpox (Jynneos) en Brasil, del 2022 al 2023. Se realizó un estudio descriptivo de los casos de mpox y de los eventos supuestamente atribuibles a la vacunación o inmunización para la vacuna Jynneos, registrados en los sistemas de información. Se calcularon frecuencias absolutas y relativas y coeficientes de notificación de eventos supuestamente atribuibles a la vacunación o inmunización por 1.000 dosis administradas. Se registraron 9.596 casos de mpox y se distribuyeron 49.000 dosis de vacuna, de estas se administraron 14.395 (31%) dosis y se reportaron 65 eventos supuestamente atribuibles a la vacunación o inmunización (4,5 por 1.000 dosis administradas). Todos los eventos supuestamente atribuibles a la vacunación o inmunización no fueron graves y 22 (33,8%) casos tuvieron reacciones relacionadas con el producto. Los resultados son acordes a la frecuencia esperada. Sin embargo, puede que el número de dosis administradas no haya sido suficiente para detectar eventos raros o inusuales. Por lo tanto, es necesaria una vigilancia continua para garantizar la eficacia y la seguridad de la vacunación, especialmente entre los grupos con mayor riesgo de contraer la enfermedad.

Abstract: This study describes the surveillance and safety actions of the mpox (Jynneos) vaccine in Brazil, from 2022 to 2023. A descriptive study of mpox cases and events supposedly attributable to vaccination and/or immunization for Jynneos vaccine, recorded in the information systems, was conducted. Absolute and relative frequencies and reporting coefficients of events supposedly attributable to vaccination and/or immunization per 1,000 administered doses were calculated. A total of 9,596 cases of mpox were registered and 49,000 doses of vaccine were distributed, of which 14,395 (31%) were administered and 65 events supposedly attributable to vaccination and/or immunization (4.5 per 1,000 administered doses) were notified. All events supposedly attributable to vaccination and/or immunization were non-serious, and 22 (33.8%) cases had product-related reactions. Results are within the expected frequency; however, the number of administered doses may not have been sufficient to detect rare or unusual events. Continued surveillance is necessary to ensure vaccination effectiveness and safety, especially among groups at higher risk for the disease.

Resumo: O objetivo deste estudo é descrever as ações de vigilância e segurança da vacina contra a mpox (Jynneos) no Brasil, de 2022 a 2023. Realizou-se estudo descritivo dos casos de mpox e dos eventos supostamente atribuíveis à vacinação e/ou imunização para vacina Jynneos, registrados nos sistemas de informação. Foram calculadas frequências absolutas e relativas e coeficientes de notificação de eventos supostamente atribuíveis à vacinação e/ou imunização por mil doses administradas. Foram registrados 9.596 casos de mpox e distribuídas 49 mil doses de vacina; dessas, 14.395 (31%) doses foram administradas e 65 eventos supostamente atribuíveis à vacinação e/ou imunização (4,5 por mil doses administradas) foram notificados. Todos os eventos supostamente atribuíveis à vacinação e/ou imunização foram não graves e 22 (33,8%) casos apresentaram reações relacionadas ao produto. Os resultados estão dentro da frequência esperada. No entanto, o número de doses administradas pode não ter sido suficiente para detectar eventos raros ou inusitados. Portanto, a vigilância contínua é necessária para garantir a efetividade e a segurança da vacinação, especialmente entre os grupos de maior risco.

https://doi.org/10.1590/0102-311xpt006624

Diretrizes Brasileiras de Medidas da Pressão Arterial Dentro e Fora do Consultório – 2023 202 20 2
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Feitosa, Audes Diogenes de Magalhães

; Barroso, Weimar Kunz Sebba

; Mion Junior, Decio

; Nobre, Fernando

; Mota-Gomes, Marco Antonio

; Jardim, Paulo Cesar Brandão Veiga

; Amodeo, Celso

; Oliveira, Adriana Camargo

; Alessi, Alexandre

; Sousa, Ana Luiza Lima

; Brandão, Andréa Araujo

; Pio-Abreu, Andrea

; Sposito, Andrei C.

; Pierin, Angela Maria Geraldo

; Paiva, Annelise Machado Gomes de

; Spinelli, Antonio Carlos de Souza

; Machado, Carlos Alberto

; Poli-de-Figueiredo, Carlos Eduardo

; Rodrigues, Cibele Isaac Saad

; Forjaz, Claudia Lucia de Moraes

; Sampaio, Diogo Pereira Santos

; Barbosa, Eduardo Costa Duarte

; Freitas, Elizabete Viana de

; Cestario, Elizabeth do Espirito Santo

; Muxfeldt, Elizabeth Silaid

; Lima Júnior, Emilton

; Campana, Erika Maria Gonçalves

; Feitosa, Fabiana Gomes Aragão Magalhães

; Consolim-Colombo, Fernanda Marciano

; Almeida, Fernando Antônio de

; Silva, Giovanio Vieira da

; Moreno Júnior, Heitor

; Finimundi, Helius Carlos

; Guimarães, Isabel Cristina Britto

; Gemelli, João Roberto

; Barreto-Filho, José Augusto Soares

; Vilela-Martin, José Fernando

; Ribeiro, José Marcio

; Yugar-Toledo, Juan Carlos

; Magalhães, Lucélia Batista Neves Cunha

; Drager, Luciano F.

; Bortolotto, Luiz Aparecido

; Alves, Marco Antonio de Melo

; Malachias, Marcus Vinícius Bolívar

; Neves, Mario Fritsch Toros

; Santos, Mayara Cedrim

; Dinamarco, Nelson

; Moreira Filho, Osni

; Passarelli Júnior, Oswaldo

; Vitorino, Priscila Valverde de Oliveira

; Miranda, Roberto Dischinger

; Bezerra, Rodrigo

; Pedrosa, Rodrigo Pinto

; Paula, Rogerio Baumgratz de

; Okawa, Rogério Toshiro Passos

; Póvoa, Rui Manuel dos Santos

; Fuchs, Sandra C.

; Lima, Sandro Gonçalves de

; Inuzuka, Sayuri

; Ferreira-Filho, Sebastião Rodrigues

; Fillho, Silvio Hock de Paffer

; Jardim, Thiago de Souza Veiga

; Guimarães Neto, Vanildo da Silva

; Koch, Vera Hermina Kalika

; Gusmão, Waléria Dantas Pereira

; Oigman, Wille

; Nadruz Junior, Wilson

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 4 elocation e20240113

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.36660/abc.20240113

Translation and cultural adaptation of the Positive Aspects of Caregiving Scale for caregivers of people living with dementia in Brazilian context: a methodological study context
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Pavarini, Sofia Cristina Iost

; Gratão, Aline Cristina Martins

; Campos, Camila Rafael Ferreira

; Monteiro, Diana Quirino

; Barham, Elizabeth Joan

; Orlandi, Fabiana de Souza

; Martins, Gabriela

; Barbosa, Gustavo Carrijo

; Cruz, Keila Cristianne Trindade da

; Corrêa, Larissa

; Rocha, Luana Aparecida da

; Alves, Ludmyla Caroline de Souza

; Ottaviani, Ana Carolina

Sao Paulo Medical Journal

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2024, Volume 142 N. 2 elocation e2023325

Abstract: En | Text: En | PDF: En

ABSTRACT BACKGROUND: The Positive Aspects of Caregiving (PAC) scale is used to assess psychosocial benefits provided to caregivers by the task of caring. The PAC scale consists of nine items, assessed using a five-point Likert scale, with higher values indicating greater positive perceptions and gains from the caregiving experience. OBJECTIVE: To translate and culturally adapt the PAC scale for informal Brazilian caregivers of people with dementia. DESIGN AND SETTING: A methodological study was conducted at the Federal University of São Carlos. METHODS: The following stages were carried out: Translation; Synthesis of the translations; Back-translation; Evaluation by an experts’ committee; and Pre-test. RESULTS: Two independent professionals translated the PAC scale. The consensus version was obtained by merging both translations, which were back-translated into English by a third translator. The expert committee comprised three specialists in the area and project researchers. All scale items presented a Content Validity Index of 1 (CVI = 1.0), and thus remained in the pre-final version of the instrument. The instrument was pre-tested with seven caregivers of people with dementia, the majority of whom were women (57.1%), with a degree of kinship corresponding to sons/daughters (57.1%) and an average age of 55.2 (± 4.1) years. The caregivers considered it clear and understandable and made no suggestions for changes. CONCLUSION: The PAC scale was translated and culturally adapted for use by informal caregivers of people with dementia in Brazil. However, a psychometric analysis of the instrument is necessary to provide normative data for this population group. BACKGROUND (PAC caring fivepoint five point experience OBJECTIVE SETTING Carlos METHODS out Translation translations Backtranslation Back translation Back-translation experts Pretest. Pretest Pre test. test Pre-test RESULTS backtranslated back translator researchers CVI 1.0, 10 1.0 , 0 1.0) prefinal pre final pretested tested 57.1%, 571 57.1% 57 sonsdaughters sons daughters (57.1% 552 55 2 55. ± ( 4.1 41 4 years changes CONCLUSION Brazil However group 1. 57.1 5 (57.1 4. 57. (57. (57 (5

https://doi.org/10.1590/1516-3180.2023.0325.r1.23012024

Sense of mastery in caregivers of people living with dementia: translation and cultural adaptation of the Pearlin Mastery Scale dementia
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Barbosa, Gustavo Carrijo

; Ottaviani, Ana Carolina

; Monteiro, Diana Quirino

; Campos, Camila Rafael Ferreira

; Cruz, Keila Cristianne Trindade da

; Alves, Ludmyla Caroline de Souza

; Corrêa, Larissa

; Rocha, Luana Aparecida

; Martins, Gabriela

; Melo, Beatriz Rodrigues de Souza

; Barham, Elizabeth Joan

; Pavarini, Sofia Cristina Iost

; Orlandi, Fabiana de Souza

; Gratão, Aline Cristina Martins

Dementia & Neuropsychologia

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2024, Volume 18 elocation e20230086

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O senso de domínio é conceituado como um aspecto positivo do cuidado voltado às pessoas que vivem com demência, um mecanismo de enfrentamento para reduzir a sobrecarga e que pode representar um fator protetor para a saúde mental e física do cuidador. Objetivo: Traduzir e adaptar culturalmente a Pearlin Mastery Scale para o Brasil. Métodos: Estudo metodológico conduzido na Universidade Federal de São Carlos, em que foram seguidas as etapas de tradução inicial; síntese; retrotradução; revisão pelo comitê de juízes pela análise do Índice de Validade de Conteúdo (IVC); e teste da versão pré-final. Resultados: Dois especialistas traduziram a escala para o português brasileiro e definiram uma versão consensual com os pesquisadores. Posteriormente, outros dois especialistas retrotraduziram a versão consensual, que foi revisada por três juízes doutores na área, considerando todos os itens da escala como muito equivalentes (IVC=1,0), mantendo-os na versão pré-final do instrumento. Esta foi testada em um primeiro grupo de cuidadores, a fim de se apontarem adequações. As sugestões foram acatadas mediante a modificação de três itens e, depois, a escala foi testada em um segundo grupo, o qual não apresentou dificuldades em responder ao instrumento. Conclusão: A Pearlin Mastery Scale foi traduzida e adaptada culturalmente para o Brasil, demonstrando equivalência. Entretanto, análises psicométricas futuras do instrumento são necessárias para disponibilizá-lo para uso entre essa população. demência cuidador Objetivo Brasil Métodos Carlos inicial síntese retrotradução IVC (IVC) préfinal. préfinal pré final. final Resultados pesquisadores Posteriormente área IVC=1,0, IVC10 IVC=1,0 , 1 0 (IVC=1,0) mantendoos mantendo cuidadores adequações depois Conclusão equivalência Entretanto disponibilizálo disponibilizá lo população (IVC IVC1 IVC=1, (IVC=1,0 IVC=1 (IVC=1, IVC= (IVC=1 (IVC=

ABSTRACT The sense of mastery is conceptualized as a positive aspect of care targeted at people living with dementia, a coping mechanism to reduce burden, and may represent a protective factor for caregivers’ mental and physical health. Objective: To translate and culturally adapt the Pearlin Mastery Scale for Brazil. Methods: A methodological study was conducted at the Federal University of São Carlos in which the initial translation stages were followed; synthesis; back-translation; review by the committee of judges by analyzing the Content Validity Index (CVI); and test of the pre-final version. Results: Two specialists translated the scale into Brazilian Portuguese and defined a consensus version with the researchers. Subsequently, another two specialists back-translated the consensus version, which was reviewed by three judges who are PhDs in the area, considering all scale items as very equivalent (CVI=1.0), and maintaining them in the pre-final version of the instrument. This was tested in a first group of caregivers for them to point out adjustments. The suggestions were accepted by modifying three items and, afterward, the scale was tested in a second group, which did not present difficulties answering the instrument. Conclusion: The Pearlin Mastery Scale was translated and culturally adapted for Brazil, showing equivalence. However, future psychometric analyses of the instrument are required to make it available for use in this population. dementia burden health Objective Brazil Methods followed synthesis backtranslation back back-translation CVI (CVI) prefinal pre final Results researchers Subsequently backtranslated area CVI=1.0, CVI10 CVI=1.0 , 1 0 (CVI=1.0) adjustments afterward Conclusion equivalence However population (CVI CVI1 CVI=1. (CVI=1.0 CVI=1 (CVI=1. CVI= (CVI=1 (CVI=

https://doi.org/10.1590/1980-5764-dn-2023-0086

Influence of postural pattern according to the Godelieve Denys-Struyf method on pain and postpartum depression in the immediate postpartum DenysStruyf Denys Struyf
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Jesus, Caroline Rodrigues de

; Ferreira, Elizabeth Alves Gonçalves

; Silveira, Leda Tomiko Yamada da

; Lunardi, Adriana Claudia

; Oliveira, Cláudia de

Fisioterapia e Pesquisa

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2024, Volume 31 elocation e23008424en

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO | O objetivo deste estudo foi avaliar a relação entre o padrão postural, de acordo com o método Godelieve Denys-Struyf (GDS), a depressão pós-parto e a dor em mulheres no puerpério imediato. Foi realizado um estudo transversal com 29 mulheres no período de 1 a 3 dias após o parto. A depressão foi avaliada por meio da Escala de Depressão Pós-parto de Edimburgo (EPDS) e a dor pela Escala Visual Numérica de dor (0=ausência de dor, 10=pior dor possível). O padrão postural foi categorizado de acordo com o plano do desvio da postura: axial (posturas ântero-medial, póstero-medial, ântero-posterior e póstero-anterior), relacional (posturas ântero-lateral e póstero-lateral) ou misto, considerando membros superiores e inferiores. Como resultados, as mulheres, entre 19 e 41 anos de idade, apresentaram índice de massa corporal entre 21,4 e 43,8 kg/m 2 . A pontuação na EPDS variou de 10 a 26 pontos. 52% das mulheres relataram sentir dor, porém a pontuação na escala de dor foi similar nos três grupos de padrão postural (p=0,77) e não houve correlação com a pontuação na EPDS (p=0,88). Os padrões posturais apresentados foram: misto (45%), relacional (38%) e axial (17%). A pontuação da EPDS foi maior para o grupo de padrão postural relacional, em comparação com o axial (20,45±1,63 vs 15,00±3,24; p=0,01). Como conclusão, o padrão postural misto foi o mais frequente entre as mulheres. O grupo com padrão postural relacional (posturas ântero-lateral e póstero-lateral) apresentou maior pontuação na EPDS que o axial. Não houve associação entre o padrão postural e a pontuação na escala de dor ou entre a dor e a depressão. DenysStruyf Denys Struyf GDS, GDS , (GDS) pósparto pós parto imediato Pósparto Pós (EPDS 0=ausência 0ausência ausência 0 10pior pior possível. possível possível) postura posturas ânteromedial, ânteromedial ântero medial, medial ântero-medial pósteromedial, pósteromedial póstero póstero-medial ânteroposterior posterior pósteroanterior, pósteroanterior anterior póstero-anterior) ânterolateral lateral pósterolateral póstero-lateral inferiores resultados 4 idade 214 21 21, 438 43 8 43, kgm kg m pontos 52 p=0,77 p077 p 77 (p=0,77 p=0,88. p088 p=0,88 88 (p=0,88) foram 45%, 45 45% (45%) 38% 38 (38% 17%. 17 17% (17%) 20,45±1,63 2045163 20 63 (20,45±1,6 15,00±3,24 1500324 15 00 24 p=0,01. p001 p=0,01 01 p=0,01) conclusão (GDS póstero-anterior 5 p=0,7 p07 7 (p=0,7 p08 p=0,8 (p=0,88 (45% (38 (17% 20,45±1,6 204516 6 (20,45±1, 15,00±3,2 150032 p00 p=0,0 p=0, p0 (p=0, (p=0,8 (45 (3 (17 20,45±1, 20451 (20,45±1 15,00±3, 15003 p=0 (p=0 (4 ( (1 20,45±1 2045 (20,45± 15,00±3 1500 p= (p= 20,45± 204 (20,45 15,00± 150 (p 20,45 (20,4 15,00 20,4 (20, 15,0 20, (20 15, (2

ABSTRACT | This study aimed to evaluate the relation between the postural pattern according to the Godelieve Denys-Struyf (GDS) method with postpartum depression and pain in immediate postpartum women. A cross-sectional study was conducted, including 29 women at 1–3 postpartum days. The Edinburgh Postnatal Depression Scale (EPDS) assessed depression and Visual Numerical Scale assessed pain score (from 0=no pain to 10=the most intense pain). Postural pattern was categorized into groups according to the deviation plane: axial (anteromedial, posteromedial, anteroposterior, and posteroanterior postures) and relational (anterolateral and posterolateral postures) or mixed, considering upper and lower limbs. Participants’ age ranged from 19 to 41 years, body mass index from 21.4 to 43.8 kg/m 2 . The EPDS scored from 10 to 26 points. In total, 52% women reported pain, but the pain score was similar among postural pattern groups (p=0.77) and not correlated with EPDS (p=0.88). Women’s postural patterns were: mixed (45%), relational (38%), and axial (17%). EPDS score was higher for relational pattern group than axial group (20.45±1.63 vs 15.00±3.24; p=0.01). In conclusion, the mixed postural pattern was the most frequent. The relational postural pattern group (anterolateral and posterolateral posture) presented a higher depression score than the axial postural pattern group. No association was found between postural patterns and the pain score or between pain and postpartum depression. DenysStruyf Denys Struyf GDS (GDS crosssectional cross sectional conducted 13 1 3 1– days (EPDS 0no no 0 10the pain. pain) plane anteromedial, anteromedial (anteromedial posteromedial anteroposterior postures anterolateral limbs Participants 4 years 214 21 21. 438 43 8 43. kgm kg m points total 52 p=0.77 p077 p 77 (p=0.77 p=0.88. p088 p=0.88 88 (p=0.88) Womens Women s were 45%, 45 45% , (45%) 38%, 38 38% (38%) 17%. 17 17% (17%) 20.45±1.63 2045163 20 63 (20.45±1.6 15.00±3.24 1500324 15 00 24 p=0.01. p001 p=0.01 01 p=0.01) conclusion frequent posture 5 p=0.7 p07 7 (p=0.7 p08 p=0.8 (p=0.88 (45% (38% (17% 20.45±1.6 204516 6 (20.45±1. 15.00±3.2 150032 p00 p=0.0 p=0. p0 (p=0. (p=0.8 (45 (38 (17 20.45±1. 20451 (20.45±1 15.00±3. 15003 p=0 (p=0 (4 (3 (1 20.45±1 2045 (20.45± 15.00±3 1500 p= (p= ( 20.45± 204 (20.45 15.00± 150 (p 20.45 (20.4 15.00 20.4 (20. 15.0 20. (20 15. (2

RESUMEN | El objetivo de este estudio fue evaluar la relación entre el patrón postural según el método Godelieve Denys-Struyf (GDS), la depresión postparto y el dolor en mujeres en el puerperio inmediato. Se realizó un estudio transversal con 29 mujeres en el período entre 1 y 3 días después del parto. Se evaluaron la depresión mediante la Escala de Depresión Postparto de Edimburgo (EPDS) y el dolor mediante la Escala Numérica Visual del Dolor (0=ningún dolor, 10=dolor intenso). El patrón postural se categorizó según el plano de la alteración postural: axial (planos anteromedial, posteromedial, anteroposterior y posteroanterior), relacional (planos anterolateral y posterolateral) o mixto considerando tanto las extremidades superiores como las inferiores. Los resultados mostraron que las mujeres, de entre 19 y 41 años de edad, tenían un índice de masa corporal entre 21,4 y 43,8 kg/m2. La puntuación de la EPDS osciló entre 10 y 26 puntos. El 52% de las mujeres declararon sentir dolor, pero la puntuación en la escala de dolor fue similar en los tres grupos de patrones posturales (p=0,77) y no hubo correlación con la puntuación de la EPDS (p=0,88). Los patrones posturales presentados fueron mixto (45%), relacional (38%) y axial (17%). La puntuación de la EPDS fue mayor en el grupo de patrón postural relacional en comparación con el axial (20,45±1,63 vs. 15,00±3,24; p=0,01). Se concluye que el patrón postural mixto fue el más frecuente entre las mujeres. El grupo con un patrón postural relacional (planos anterolateral y posterolateral) obtuvo mayores tasas en la EPDS que el axial. No hubo asociación entre el patrón postural y la puntuación en la escala de dolor ni entre el dolor y la depresión. DenysStruyf Denys Struyf GDS, GDS , (GDS) inmediato 2 parto (EPDS 0=ningún 0ningún ningún 0 10dolor intenso. intenso . intenso) planos anteromedial posteromedial posteroanterior, posteroanterior posteroanterior) posterolateral inferiores 4 edad 214 21 21, 438 43 8 43, kgm2 kgm kg m2 m kg/m2 puntos 52 p=0,77 p077 p 77 (p=0,77 p=0,88. p088 p=0,88 88 (p=0,88) 45%, 45 45% (45%) 38% 38 (38% 17%. 17 17% (17%) 20,45±1,63 2045163 20 63 (20,45±1,6 vs 15,00±3,24 1500324 15 00 24 p=0,01. p001 p=0,01 01 p=0,01) (GDS kg/m 5 p=0,7 p07 7 (p=0,7 p08 p=0,8 (p=0,88 (45% (38 (17% 20,45±1,6 204516 6 (20,45±1, 15,00±3,2 150032 p00 p=0,0 p=0, p0 (p=0, (p=0,8 (45 (3 (17 20,45±1, 20451 (20,45±1 15,00±3, 15003 p=0 (p=0 (4 ( (1 20,45±1 2045 (20,45± 15,00±3 1500 p= (p= 20,45± 204 (20,45 15,00± 150 (p 20,45 (20,4 15,00 20,4 (20, 15,0 20, (20 15, (2

https://doi.org/10.1590/1809-2950/e23008424en

10.

Fatores contextuais do desempenho do atendimento odontológico para gestantes na Atenção Básica entre municípios baianos
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Silva Junior, Manoelito Ferreira

; Saraiva, Amanda Cristina Laranjeira

; Matos, Patrícia Elizabeth Souza

Saúde em Debate

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2024, Volume 48 N. 140 elocation e8844

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

ABSTRACT This study aimed to analyze the contextual factors of the performance of dental care for pregnant women in Primary Care among municipalities in Bahia. The time series used secondary data from 417 municipalities between 2018-2022. The outcome was the target indicator for the proportion of pregnant women with dental care per municipality: insufficient (<60.0%) or sufficient (≥60.0%). The contextual variables were: sociodemographic factors (Population Size, Municipal Human Development Index, municipal Gross Domestic Product per capita – GDP, Gini Index of household income per capita, Social Vulnerability Index and Regional Health Centers) and health service (Coverage of Family Health Strategy – ESF and Oral Health). Poisson regression was performed (p<0.05). In the last four months of each year: 2.9% (2018), 2.4% (2019), 5.3% (2020), 37.2% (2021) and 71.2% (2022) of the municipalities reached the goal. In the third four months of 2021, municipalities with lower GDP, and in 2021 and 2022, with greater ESF coverage, had a greater chance of reaching the target. It is concluded that there was an increase in the proportion of dental care for pregnant women over the years among the municipalities in Bahia, and achieving the goal was associated with sociodemographic and health service factors. Bahia 41 20182022. 20182022 2018 2022. 2022 2018-2022 municipality <60.0% 600 60 0 (<60.0% ≥60.0%. ≥60.0% . (≥60.0%) were Population Size GDP Centers Coverage Health. Health) p<0.05. p005 p p<0.05 05 (p<0.05) year 29 2 9 2.9 2018, , (2018) 24 4 2.4 2019, 2019 (2019) 53 5 3 5.3 2020, 2020 (2020) 372 37 37.2 (2021 712 71 71.2 (2022 202 coverage 2018202 201 2018-202 <60.0 6 (<60.0 ≥60.0 (≥60.0% p00 p<0.0 (p<0.05 2. (2018 (2019 5. (2020 37. (202 7 71. 20 201820 2018-20 <60. (<60. ≥60. (≥60.0 p0 p<0. (p<0.0 (201 (20 20182 2018-2 <60 (<60 ≥60 (≥60. p<0 (p<0. (2 2018- <6 (<6 ≥6 (≥60 p< (p<0 ( < (< ≥ (≥6 (p< (≥ (p

https://doi.org/10.1590/2358-289820241408844p

11.

Insights from a Wolfram syndrome cohort: clinical and molecular findings from a specialized diabetes reference center cohort
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Lopes, Carolina Paniago

; Gonçalves Neto, Gentil Ferreira

; Paulino, Maria Fernanda Vanti Macedo

; Esquiaveto-Aun, Adriana Mangue

; de Mello, Maricilda Palandi

; Pavin, Elizabeth João

; Breder, Ikaro Soares Santos

; Pu, Mariana Zorron Mei Hsia

; de Lemos-Marini, Sofia Helena Valente

; Guerra Junior, Gil

Archives of Endocrinology and Metabolism

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2024, Volume 68 elocation e240091

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: Considering the rarity and clinical and molecular diversity of Wolfram syndrome (WS), the objective of this study was to identify patients with a clinical presentation suggestive of WS following up at a single Brazilian diabetes service and analyze their clinical and molecular characteristics. Subjects and methods: The study included all patients with a clinical presentation of WS following up between 1991 and 2022 with early-onset diabetes mellitus and other WS signs and symptoms. A retrospective analysis was conducted, including patients’ age, sex, consanguinity, age at symptom onset, diagnosis of diabetes mellitus, optic atrophy, diabetes insipidus, neurological and psychiatric disorders, hearing loss, urinary disorders, hypogonadism, and WFS1 molecular analysis. Results: Eight patients were identified, all of whom were diagnosed with diabetes mellitus at an average age of 3.7 years. Optic atrophy, diabetes insipidus, and hearing loss were common, while psychiatric and neurological alterations were observed in some cases. Genetic analysis revealed pathogenic variants in homozygosity or compound heterozygosity. The most frequent variant was p. Val412Serfs29, present in five of the seven families. Conclusions: This study represents the second-largest Brazilian sample of WS and is the first cohort from a single center in Southeast Brazil. The patients had an early, severe, and complete clinical presentation. The genetic variants identified were consistent with previous literature descriptions. The variant p. Val412Serfs29 was particularly common in this cohort, highlighting its relevance in the region. Objective WS, , (WS) characteristics methods 199 202 earlyonset early onset symptoms conducted sex consanguinity atrophy insipidus disorders hypogonadism WFS Results 37 3 7 3. years cases heterozygosity p ValSerfs Val Serfs families Conclusions secondlargest second largest Brazil severe descriptions Val412Serfs2 region (WS 19 20 Val412Serfs 1 2

https://doi.org/10.20945/2359-4292-2024-0091

12.

In vitro microbiological analysis of bacterial sealing at the interface between abutment and small-diameter implants after mechanical cycling smalldiameter small diameter
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Lobo, João Paulo Borre

; Joly, Júlio Cesar

; Teixeira, Lucas Novaes

; Martinez, Elizabeth Ferreira

RGO - Revista Gaúcha de Odontologia

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2024, Volume 72 elocation e20240049

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O objetivo deste estudo in vitro foi avaliar o selamento bacteriano da interface entre o pilar protético e o implante na conexão cônica do implante de 2,9 mm de diâmetro. A pesquisa utilizou dois conjuntos de implante/pilar protético (G1 e G2) para análise. Um grupo (G1) foi previamente submetido a ciclagem mecânica, com 500.000 ciclos por amostra, recebendo uma carga de 120 N com inclinação de 30° a 2 Hz. Para análise microbiológica, cada amostra foi imersa em uma suspensão de Escherichia coli e incubada a 37 °C. Após 14 dias, os pilares protéticos foram separados dos respectivos implantes, os valores de torque reverso foram registrados, e a presença de penetração bacteriana foi avaliada. Os testes de distribuição t de Student e binomial foram utilizados para os cálculos estatísticos, adotando-se um nível de significância de 5%. Não houve diferença significativa entre os valores de torque reverso e a proporção de falha de selamento microbiano. Houve contaminação em 33% das amostras do grupo G1 e 0% no grupo G2. Não houve diferença significativa entre os valores de torque reverso nos grupos avaliados e no selamento bacteriano com ou sem ciclagem mecânica (p>0,05). Portanto, os resultados deste estudo mostraram que implantes com plataforma de 2,9 mm foram eficazes no selamento microbiológico, independentemente da ciclagem mecânica, evidenciando a precisão e previsibilidade do sistema. 29 9 2, diâmetro implantepilar G (G G2 500000 500 000 500.00 12 30 Hz microbiológica 3 C °C 1 dias registrados avaliada estatísticos adotandose adotando se 5 5% microbiano 33 0 p>0,05. p005 p p>0,05 . 05 (p>0,05) Portanto microbiológico sistema 50000 50 00 500.0 p00 p>0,0 (p>0,05 5000 500. p0 p>0, (p>0,0 p>0 (p>0, p> (p>0 (p> (p

ABSTRACT The objective of this in vitro study was to evaluate the bacterial sealing of the abutment interface and implant in the conical connection of the 2.9mm diameter implant. The research used two sets of screw-in / prosthetic abutment (G1 and G2) for analysis. One group (G1) was previously subjected to mechanical cycling, 500000 cycles per sample, receiving a load of 120N with 30° inclination at 2 Hz. For microbiological analysis, each sample was immersed in Escherichia coli suspension and incubated at 37°C. After 14 days, the abutments were separated from the respective implants, the reverse torque values were recorded and the presence of bacterial penetration was evaluated. Student’s t-distribution and binomial tests were used for the statistical calculations, and a significance level of 5% was adopted. There was no significant difference between the reversal torque values and the proportion of turbid broths. There was contamination in 33% samples and in group G1 and 0% in group G2. There was no significant difference between the values of the reverse torque in the evaluated groups and bacterial sealing with or without mechanical cycling (p>0.05). Therefore, the results of this study showed that implants with platform of 2.9 mm were effective in microbiological sealing, independent of the mechanical cycling, evidencing the accuracy and predictability of the system. 29mm 9mm screwin screw G (G G2 analysis 50000 N 30 Hz 37C C 37 37°C 1 days Students Student s tdistribution t distribution calculations 5 adopted broths 33 0 p>0.05. p005 p p>0.05 . 05 (p>0.05) Therefore 29 9 2. system 5000 3 p00 p>0.0 (p>0.05 500 p0 p>0. (p>0.0 50 p>0 (p>0. p> (p>0 (p> (p

https://doi.org/10.1590/1981-86372024004920240082

13.

Genetic base and origin of cytoplasmic genes of Brazilian cowpea cultivars
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Meireles, Marcos Garreto

; Silva, Edson Ferreira da

; Veasey, Elizabeth Ann

; Siqueira, Marcos Vinícius Bohrer Monteiro

; Nascimento, Wellington Ferreira do

Crop Breeding and Applied Biotechnology

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2024, Volume 24 N. 4 elocation e49952446

Abstract: En | Text: En | PDF: En

Abstract The expansion of cowpea (Vigna unguiculata (L.) Walp.) crop has created new demands for its breeding programs. Knowledge of its genetic base is fundamental for choosing progenitors when conducting crosses. This study aimed to estimate the genetic base of Brazilian cowpea cultivars released between 1960 and 2022, in addition to identifying the origin of their cytoplasmic genes. Seventy-three cultivars were released in this period; however, only 41 had information about their original crosses. The ancestors CNC0434, Pitiúba and Seridó were used more frequently in crosses. They have also contributed with the highest frequency to the cultivars’ cytoplasmic genes. Therefore, although we found that between 2005 and 2022 there was a 30.95% increase in the contribution of different genotypes, we conclude that the genetic base of cowpea is narrow, and it is necessary to avoid crosses involving CNC0434, Pitiúba and Seridó in future breeding programs of this legume in Brazil. Vigna L. L (L. Walp. Walp 196 genes Seventythree Seventy three period however 4 CNC0434 CNC Therefore 200 202 3095 30 95 30.95 genotypes narrow Brazil (L 19 CNC043 20 309 3 9 30.9 1 CNC04 2 30. CNC0

https://doi.org/10.1590/1984-70332024v24n4a43

14.

Culture and commitment as antecedents of performance in the food and beverage sector
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Oliveira, Paulo Sergio Gonçalves de

; Mathias, Bruno Santana

; Wada, Elizabeth Kyoko

; Silva, Luciano Ferreira da

Revista de Administração da UFSM

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2024, Volume 17 N. 2 elocation e1

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo O objetivo do artigo foi analisar o impacto da cultura organizacional e do comprometimento do antecedente no desempenho organizacional de restaurantes localizados na cidade de São Paulo para explicar a relação entre as variáveis exógenas do modelo, fornecendo assim aos gerentes um parâmetro de como as dimensões de cultura, comprometimento e desempenho devem ser gerenciadas. Projeto/metodologia/abordagem Os dados foram analisados por meio da análise de equações estruturais (PLS-PM) e foram coletados por meio de um questionário com 45 assertivas, durante o período de 2 meses, obtendo-se 116 respostas válidas. Resultados Quatro hipóteses foram suportadas - H1- A cultura inovadora influencia positivamente o comprometimento afetivo dos funcionários do restaurante (Γ=0,466), H8 - A cultura de apoio influencia o comprometimento normativo (Γ=0,270), H9 - A cultura de apoio influencia o comprometimento de continuidade (Γ=0,293), H10 - O comprometimento afetivo influencia positivamente o desempenho do bar e do restaurante (Γ=0,293). Implicações gerenciais O modelo obtido com o desenvolvimento deste estudo pode ser usado pelos gerentes de restaurantes para gerenciar seus funcionários com o objetivo de melhorar o desempenho organizacional. Implicações práticas As implicações práticas desse modelo foram o fato de que ele pode ser usado para orientar as decisões dos restaurantes em relação ao movimento de melhoria do desempenho. Originalidade/valor A lacuna que o estudo preenche é a proposição de um modelo gerencial que leva em consideração os aspectos da gestão de pessoas, como a cultura e o engajamento da equipe, para melhorar o desempenho organizacional de bares e restaurantes. gerenciadas Projetometodologiaabordagem Projeto metodologia abordagem PLSPM PLS PM (PLS-PM 4 assertivas meses obtendose obtendo se 11 válidas H1 H Γ=0,466, Γ0466 Γ Γ=0,466 , 0 466 (Γ=0,466) Γ=0,270, Γ0270 Γ=0,270 270 (Γ=0,270) Γ=0,293, Γ0293 Γ=0,293 293 (Γ=0,293) Γ=0,293. . Originalidadevalor Originalidade valor pessoas equipe 1 Γ046 Γ=0,46 46 (Γ=0,466 Γ027 Γ=0,27 27 (Γ=0,270 Γ029 Γ=0,29 29 (Γ=0,293 Γ04 Γ=0,4 (Γ=0,46 Γ02 Γ=0,2 (Γ=0,27 (Γ=0,29 Γ0 Γ=0, (Γ=0,4 (Γ=0,2 Γ=0 (Γ=0, Γ= (Γ=0 (Γ= (Γ

Abstract Purpose The objective of the article is to verify the influence of antecedents such as culture and commitment on restaurant organisational performance and assess how they can impact managerial practices. This would explain the relationship between the exogenous variables of the model, thus providing managers with a parameter for managing the dimensions of culture, commitment, and performance. Design/methodology/approach Data were analysed using structural equation analysis (PLS-PM) and collected through a questionnaire with 45 assertions over a period of 2 months, obtaining 116 valid answers. Findings Four hypotheses were supported: H1—Innovative culture positively influences the affective commitment of restaurant employees (Γ=0.466); H8—Supportive culture influences normative commitment (Γ=0.270); H9—Supportive culture influences continuance commitment (Γ=0.293); and H10—Affective commitment positively influences bar and restaurant performance (Γ=0.293). Managerial contributions The model developed for this study can be used by restaurant managers to manage their employees and improve their organisational performance. Practical implications This model’s practical implications were that it could be used to guide restaurant decisions toward performance improvement. Originality/value The study fills a gap by proposing a managerial model that considers aspects of people management, such as culture and staff engagement, to improve the organisational performance of bars and restaurants. practices Designmethodologyapproach Design methodology approach PLSPM PLS PM (PLS-PM 4 months 11 answers supported H1Innovative HInnovative H1 Innovative H Γ=0.466 Γ0466 Γ 0 466 (Γ=0.466) H8Supportive HSupportive H8 Supportive Γ=0.270 Γ0270 270 (Γ=0.270) H9Supportive H9 Γ=0.293 Γ0293 293 (Γ=0.293) H10Affective HAffective H10 Affective Γ=0.293. . models s improvement Originalityvalue Originality value management engagement restaurants 1 Γ=0.46 Γ046 46 (Γ=0.466 Γ=0.27 Γ027 27 (Γ=0.270 Γ=0.29 Γ029 29 (Γ=0.293 Γ=0.4 Γ04 (Γ=0.46 Γ=0.2 Γ02 (Γ=0.27 (Γ=0.29 Γ=0. Γ0 (Γ=0.4 (Γ=0.2 Γ=0 (Γ=0. Γ= (Γ=0 (Γ= (Γ

https://doi.org/10.5902/1983465973964

15.

Drug Repositioning and Artificial Intelligence: Is It a Promising Approach to be Used for Neglected Diseases? Intelligence Diseases
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Bongiovani, Fernanda

; Ferreira- Junior, Marcos A.

; Santos, Soraya S.

; Vargas, Jeanine G.

; Ferreira, Elizabeth I. A.

Journal of the Brazilian Chemical Society

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2024, Volume 35 N. 10 elocation e-20240159

Abstract: En | Text: En | PDF: En

Drug repositioning involves the use of a determined drug in a different indication and has been widely used for some therapeutic classes. Artificial intelligence, in turn, has been a trend in the modern world of innovation, including in drug design. Those approaches are apparently paradoxical (the former is not considered as properly an innovative method to introduce new molecules/drugs into the market, although the latter is) can be used as complementary. In this review, we present some concepts of both methods, their advantages, possible disadvantages, and some applications in drug design in general to improve different aspects of drug development. Examples of the use of both methods together have been given for many therapeutic classes. Notwithstanding, their application in the search for drugs for neglected diseases, although somehow stimulated, deserves more discussion, mainly in light of the social aspects of these infections. classes intelligence turn innovation moleculesdrugs molecules market complementary review advantages disadvantages development Notwithstanding diseases stimulated discussion infections

https://doi.org/10.21577/0103-5053.20240159

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