ABSTRACT Arbuscular mycorrhizal fungi increase water and nutrient absorption from the soil by plants. However, its benefits to plants vary depending on the inoculated species. This study aimed to determine the influence of different species of mycorrhizal fungi on the development and productivity of grain sorghum cultivars. The experiment was conducted in a greenhouse in a completely randomized design in a 2 x 5 factorial scheme, consisting of two sorghum cultivars (BRS 310 and BRS 330) and five treatments (control without inoculation and four species of arbuscular mycorrhizal fungi: Gigaspora margarita, Glomus formosanum, Acaulospora scrobiculata, and Scutellospora pellucida), with four replications. Plant height, stem diameter, leaf area, length, volume, specific surface area, root diameter, shoot dry mass, root dry mass, thousand-grain weight, grain productivity, colonization, dependence, and mycorrhizal efficiency were evaluated. The results showed that inoculation with the species S. pellucida induced higher root and shoot development of plants of the cultivar BRS 310, as well as higher productivity of sorghum grains. The cultivar BRS 330 showed higher root development when inoculated with the species G. formosanum and a higher shoot development when inoculated with the species A. scrobiculata. Mycorrhizal dependence for grain productivity was low and varied with the inoculated species of mycorrhizal fungi. The mycorrhizal efficiency for shoot dry mass was higher with the inoculation of A. scrobiculata and S. pellucida in the cultivar BRS 310 and A. scrobiculata and G. margarita in the cultivar BRS 330. However scheme 31 control pellucida, , pellucida) replications height diameter area length volume thousandgrain thousand weight colonization evaluated S grains 33 G A 3

RESUMO: O estudo foi realizado em um ovino, fêmea, de três anos de idade, da raça santa inês, procedente de uma propriedade localizada do município de Santo Antônio de Tauá, oeste do Pará. O animal acometido tinha histórico de exoftalmia no olho esquerdo, secreção nasal e dificuldade respiratória há mais de três meses. Ao exame físico o animal apresentava baixo escore corporal, apatia, assimetria facial unilateral, moderada exoftalmia unilateral esquerda, dispneia mista e exsudação nasal serossanguinolenta profusa unilateral. À necropsia, foi observada grande massa nasal, predominantemente branco-amarelada com áreas vermelho enegrecidas, de superfície irregular, finamente granular, úmida e friável. A massa invadia desde a junção mucocutânea do nariz esquerdo até as coanas, se infiltrava pelos seios nasais frontais, placa cribiforme e alcançava as meninges e a porção frontal do cérebro. À microscopia da superfície do epitélio nasal notou-se severa destruição dos cornetos e dos epitélios, evidenciada por extensas áreas de necrose com muitos debris celulares, ulceração e infecção bacteriana secundária. No sistema nervoso central (SNC) havia meningite piogranulomatosa com acentuada congestão de vasos, focos de necrose e inflamação granulomatosa. O diagnóstico de rinite granulomatosa de origem micótica associada ao fungo Conidiobolus lamprauges foi baseado nos achados da imuno-histoquímica. RESUMO ovino fêmea idade inês Tauá Pará meses corporal apatia esquerda necropsia brancoamarelada branco amarelada enegrecidas irregular granular friável coanas frontais cérebro notouse notou epitélios celulares secundária SNC (SNC vasos imunohistoquímica. imunohistoquímica imuno histoquímica. histoquímica imuno-histoquímica

ABSTRACT: The study was conducted on a 3-year-old female Santa Inês sheep from a property located in the municipality of Santo Antônio de Tauá, west of Pará. The affected animal had a history of exophthalmos in the left eye, nasal discharge, and breathing difficulty for more than three months. On physical examination, the animal had a low body score, apathy, unilateral facial asymmetry, moderate unilateral left exophthalmos, mixed dyspnea and unilateral profuse serosanguinous nasal discharge. At necropsy, a large nasal mass was observed, predominantly yellowish-white with blackish-red areas, with an irregular, finely granular, moist, and friable surface. The mass invaded from the mucocutaneous junction of the left nostril to the choanae, infiltrated the frontal sinuses, the cribiform plate, and reached the meninges and the frontal portion of the brain. Microscopy of the surface of the nasal epithelium showed severe destruction of the turbinates and epithelia, evidenced by extensive areas of necrosis with a large amount of cellular debris, ulceration, and secondary bacterial infection. In the central nervous system there was pyogranulomatous meningitis with marked vessel congestion, as well as foci of necrosis and granulomatous inflammation. Immunohistochemistry showed intense staining of numerous intralesional hyphae for antibodies against Conidiobolus lamprauges. The diagnosis of granulomatous rhinitis of mycotic origin associated with the Conidiobolus lamprauges was based on epidemiological, clinical-pathological, and immunohistochemical data. ABSTRACT 3yearold yearold 3 year old Tauá Pará eye discharge months examination score apathy asymmetry necropsy observed yellowishwhite yellowish white blackishred blackish red irregular granular moist choanae sinuses plate brain epithelia debris ulceration infection congestion inflammation epidemiological clinicalpathological, clinicalpathological clinical pathological, pathological clinical-pathological data

RESUMO O cultivo do milho convencional em áreas de refúgio é importante para preservação da tecnologia Bt e para atender mercados específicos com maior valor agregado aos grãos. Portanto, as pesquisas voltadas ao controle químico de plantas daninhas também devem continuar direcionadas aos híbridos convencionais de milho. O objetivo foi avaliar a seletividade de herbicidas aplicados em pré e pós-emergência de um híbrido convencional de milho cultivado no bioma Cerrado do Brasil. Foram instalados dois experimentos de campo, um na safra verão e outro segunda safra. Os tratamentos foram onze herbicidas, cujas doses são apresentadas em g ha-1 de ingrediente ativo: S-metolachlor (1.680), mesotrione + atrazine (115,2 + 2.000), mesotrione + atrazine (192 + 2.000), tembotrione + atrazine (75,6 + 2.000), tembotrione + atrazine (100,8 + 2.000), nicosulfuron + atrazine (16 + 2.000), nicosulfuron + atrazine (24 + 2.000), [mesotrione + atrazine] ([120 + 1.,200]), aplicação sequencial de [mesotrione + atrazine] ([60 + 600]), atrazine (2.000), mais testemunha capinada. Independentemente do experimento, todos os herbicidas aplicados pré e pós-emergência do milho proporcionaram baixos percentuais de fitointoxicação. Em ambos os experimentos nenhum dos tratamentos causou redução no estande, confirmando a ausência de mortalidade das plantas pela aplicação de herbicidas. O tombamento/acamamento das plantas foi observado no experimento realizado de verão e não observou efeito entre tratamentos. Massa de 100 grãos e produtividade do milho não alteraram em função da aplicação de herbicidas na pré e pósemergência da cultura. Todos os tratamentos herbicidas avaliados apresentaram seletividade ao híbrido de milho convencional. Portanto pós emergência Brasil campo ha1 ha 1 ha- ativo Smetolachlor S metolachlor 1.680, 1680 1.680 , 680 (1.680) 115,2 1152 115 2 (115, 2.000, 2000 2.000 000 2.000) 192 (19 75,6 756 75 6 (75, 100,8 1008 8 (100, 16 (1 24 (2 120 ([12 1.,200, 1200 1.,200 200 1.,200]) 60 ([6 600, 600 600]) (2.000) capinada fitointoxicação estande tombamentoacamamento tombamento acamamento 10 cultura 168 1.68 68 (1.680 115, 11 (115 2.00 00 19 75, 7 (75 100, (100 ( 12 ([1 1.,20 20 1.,200] ([ 600] (2.000 1.6 (1.68 (11 2.0 0 (7 (10 1.,2 (2.00 1. (1.6 2. 1., (2.0 (1. (2.

ABSTRACT The cultivation of conventional maize in refuge areas is important for preserving Bt technology and serving specific markets with greater added value to the grains. Therefore, research aimed at chemical weed control must also continue to be directed to conventional maize hybrids. The objective was to evaluate the selectivity of herbicides applied in preand post-emergence of a conventional maize hybrid cultivated in the Cerrado biome of Brazil. Two field experiments were set up, one in summer and the other in second season. The treatments were composed of eleven herbicide treatments, whose doses are presented in g ha-1 of active ingredient: S-metolachlor (1,440), S-metolachlor (1,680), mesotrione + atrazine (115.2 + 2,000), mesotrione + atrazine (192 + 2,000), tembotrione + atrazine (75.6 + 2,000), tembotrione + atrazine (100.8 + 2,000), nicosulfuron + atrazine (16 + 2,000), nicosulfuron + atrazine (24 + 2,000), [mesotrione + atrazine] ([120 + 1,200]), sequential application of [mesotrione + atrazine] ([60 + 600]), atrazine (2,000), plus a weeded control. Regardless of the experiment, all herbicides applied preand post-emergence of maize led to low percentages of phytointoxication. In both experiments, none of the treatments caused reductions in crop stand, confirming the absence of plant mortality due to the application of herbicides. Plant tipping/lodging was seen in summer maize, with no treatment effect. Maize 100grain mass and yield did not change as a result of the application of herbicides in preand post-emergence of the crop. All herbicide treatments evaluated showed selectivity for the conventional maize hybrid. grains Therefore hybrids postemergence post emergence Brazil up season ha1 ha 1 ha- ingredient Smetolachlor S metolachlor 1,440, 1440 1,440 , 440 (1,440) 1,680, 1680 1,680 680 (1,680) 115.2 1152 115 2 (115. 2,000, 2000 2,000 000 2,000) 192 (19 75.6 756 75 6 (75. 100.8 1008 100 8 (100. 16 (1 24 (2 120 ([12 1,200, 1200 1,200 200 1,200]) 60 ([6 600, 600 600]) (2,000) experiment phytointoxication stand tippinglodging tipping lodging effect grain 144 1,44 44 (1,440 168 1,68 68 (1,680 115. 11 (115 2,00 00 19 75. 7 (75 100. 10 (100 ( 12 ([1 1,20 20 1,200] ([ 600] (2,000 14 1,4 4 (1,44 1,6 (1,68 (11 2,0 0 (7 (10 1,2 (2,00 1, (1,4 (1,6 2, (2,0 (1, (2,

ABSTRACT Purpose: To describe the ophthalmological findings of dry eye disease and its relation to the quality of life of COVID-19 survivors. Methods: COVID-19 survivors who had previously been hospitalized at Hospital das Clínicas de Ribeirão Preto complex underwent an ophthalmological evaluation, which included a dry eye disease questionnaire, break-up time, fluorescein staining, and Schirmer test. We collected the presenting and best-corrected visual acuity, sociodemographic data, personal medical history, and scores from a self-reported quality of life questionnaire (WHOQOL-bref). According to the severity of the acute phase of the disease, the patients were classified into mild-to-moderate, severe, and critical groups. Results: Ninety-five patients (190 eyes) were evaluated 100 ± 44 days after the onset of COVID-19 symptoms. Of these, 83 patients (87.3%) completed the WHOQOL-bref questionnaire. Ten patients (12.0%) had mild-to-moderate COVID-19, 41 (49.4%) had severe COVID-19, and 32 (38.6%) had critical COVID-19. The median best-corrected visual acuity was logMAR 0 (0-1). Approximately 26.3% patients had a history of dry eye disease or severe dry eye symptoms (frequent or constant ocular dryness and irritation). There was an association between the proportion of patients with dry eye disease and the quality of life (p=0.014) and health (p=0.001). Furthermore, there was a significant trend between the proportion of patients with dry eye disease and how they rated their health and quality of life (p=0.0004 and 0.0027, respectively. Conclusions: There is a significant negative correlation between the proportion of patients with dry eye disease and their self-reported quality of life. Purpose COVID19 COVID 19 COVID-1 Methods evaluation breakup break up time staining test bestcorrected best corrected data selfreported self reported WHOQOLbref. WHOQOLbref WHOQOL bref . (WHOQOL-bref) mildtomoderate, mildtomoderate mild moderate, moderate groups Results Ninetyfive Ninety five 190 (19 eyes 10 4 these 8 87.3% 873 87 3 (87.3% 12.0% 120 12 (12.0% COVID19, 19, 49.4% 494 49 (49.4% 38.6% 386 38 6 (38.6% COVID19. 19. 01. 01 1 (0-1) 263 26 26.3 frequent irritation. irritation irritation) p=0.014 p0014 p 014 (p=0.014 p=0.001. p0001 p=0.001 001 (p=0.001) Furthermore p=0.0004 p00004 0004 (p=0.000 00027 0027 0.0027 respectively Conclusions COVID1 COVID- (WHOQOL-bref (1 87.3 (87.3 12.0 (12.0 49.4 (49.4 38.6 (38.6 (0-1 2 26. p=0.01 p001 (p=0.01 p000 p=0.00 00 (p=0.001 p=0.000 p0000 000 (p=0.00 0002 002 0.002 ( 87. (87. 12. (12. 49. (49. 38. (38. (0- p=0.0 p00 (p=0.0 0.00 (87 (12 (49 (38 (0 p=0. p0 (p=0. 0.0 (8 (4 (3 p=0 (p=0 0. p= (p= (p

ABSTRACT This study investigated 27 male adolescents in socio-educational care at the Belford Roxo Intensive Care Center. It is a descriptive exploratory study with a qualitative approach and a case study methodological proposal. To obtain data, questionnaires were applied that consisted of obtaining answers about i) sociodemographic data, ii) screening for involvement with smoking, alcohol and other drugs, iii) Beck Depression Inventory and iv) Beck suicidal ideation. The group studied was composed of 16.48 years old as a mean; 92.6% were brown or black; 70.37% had attended between the 5th grade of Elementary School I and the 9th grade of Elementary School II; 44.44% consumed alcoholic beverages daily; 40.74% presented depressive symptoms; 25.92% had a history of suicidal ideation, and 11.11% had already attempted suicide. Those surveyed with substance use problems face a high simultaneous risk of mental health problems, an aggravating factor that can result in a more difficult life situation with diffuse social problems, a precarious health status, and a prediction of general adversity. Thus, the situation of these adolescents, who are a sample of the peripheral underworld of cities, is alarming, indicating the urgency of public health and state actions.

RESUMO Este estudo pesquisou 27 adolescentes do sexo masculino em regime socioeducativo no Centro de Atendimento Intensivo Belford Roxo. É um estudo descritivo exploratório de abordagem qualitativa com proposta metodológica de estudo de caso. Na obtenção de dados, foram aplicados questionários que consistiram em obter respostas sobre i) dados sociodemográficos, ii) triagem do envolvimento com fumo, álcool e outras drogas, iii) Inventário Beck de depressão e iv) ideação suicida de Beck. O grupo pesquisado era composto de 16,48 anos como média de idade; percentual de 92,6% de cor parda ou preta; 70,37% tinham frequentado entre a 5ª série do Ensino Fundamental I e a 9ª série do Ensino Fundamental II; 44,44% faziam uso de bebidas alcoólicas diuturnamente; 40,74% apresentaram sintomas depressivos; 25,92% apresentaram histórico de ideação suicida, e 11,11% já tinham tentado suicídio. Os pesquisados com problemas de uso de substâncias psicoativas enfrentam um alto risco simultâneo de saúde mental, agravante que pode incorrer em situação de vida mais difícil com problemas sociais difusos, um quadro de saúde precário, prognosticando adversidades gerais. Dessa forma, é alarmante a situação desses adolescentes, que é uma amostra do submundo periférico das cidades, denotando a urgência de ações de saúde pública e do Estado.

ABSTRACT Care for human well-being and health requires the consumption of healthy foods, and therefore, the “baby-leaf” gains increased space in the market as they have higher concentrations of bioactive compounds. The present study aimed to evaluate the growth and bioactive compounds of baby-leaf chicory (Cichorium intybus L.) according to the color of cultivation benches with different wavelengths. The experiment was conducted in a non-acclimatized greenhouse, covered with low density polyethylene film with an aluminized screen of 50% shading under the film and 50% shading screens on the sides. In a completely randomized design, five types of benches were evaluated without and with bright reflective colored materials: Control bench without reflective material, a bench with reflective bright white laminate, reflective bright dark red laminate, reflective bright dark blue laminate, and reflective bright yellow laminate. The bright white and yellow laminates amplified the most photosynthetically active radiation. All the laminates enhanced yield of baby-leaf chicory plants, where white, yellow, red, and dark blue enhanced the fresh matter by 102.6%, 50.2%, 60.6%, and 37.4% compared to the control, respectively. The bright dark blue laminates enhanced the bioactive compounds of baby-leaf chicory plants. The bright dark blue laminate enhanced the carotenoid production of baby-leaf chicory plants by 11.0%. The use of colored laminates was effective in the cultivation of baby-leaf chicory, both in terms of yield and quality, with significant increases in fresh matter and bioactive compounds. To provide baby-leaf chicory with higher bioactive content with antioxidant effect (carotenoids) the use of dark blue laminates is necessary; however, if the objective is greater shoot DM it will be white laminates.

ABSTRACT This study investigated 27 male adolescents in socio-educational care at the Belford Roxo Intensive Care Center. It is a descriptive exploratory study with a qualitative approach and a case study methodological proposal. To obtain data, questionnaires were applied that consisted of obtaining answers about i) sociodemographic data, ii) screening for involvement with smoking, alcohol and other drugs, iii) Beck Depression Inventory and iv) Beck suicidal ideation. The group studied was composed of 16.48 years old as a mean; 92.6% were brown or black; 70.37% had attended between the 5th grade of Elementary School I and the 9th grade of Elementary School II; 44.44% consumed alcoholic beverages daily; 40.74% presented depressive symptoms; 25.92% had a history of suicidal ideation, and 11.11% had already attempted suicide. Those surveyed with substance use problems face a high simultaneous risk of mental health problems, an aggravating factor that can result in a more difficult life situation with diffuse social problems, a precarious health status, and a prediction of general adversity. Thus, the situation of these adolescents, who are a sample of the peripheral underworld of cities, is alarming, indicating the urgency of public health and state actions. 2 socioeducational socio educational Center proposal data i ii smoking drugs iii iv ideation 1648 16 48 16.4 mean 926 92 6 92.6 black 7037 70 37 70.37 th II 4444 44 44.44 daily 4074 40 74 40.74 symptoms 2592 25 25.92 1111 11 11.11 suicide status adversity Thus cities alarming actions 164 1 4 16. 9 92. 703 7 3 70.3 444 44.4 407 40.7 259 25.9 111 11.1 70. 44. 40. 25. 11.

RESUMO Este estudo pesquisou 27 adolescentes do sexo masculino em regime socioeducativo no Centro de Atendimento Intensivo Belford Roxo. É um estudo descritivo exploratório de abordagem qualitativa com proposta metodológica de estudo de caso. Na obtenção de dados, foram aplicados questionários que consistiram em obter respostas sobre i) dados sociodemográficos, ii) triagem do envolvimento com fumo, álcool e outras drogas, iii) Inventário Beck de depressão e iv) ideação suicida de Beck. O grupo pesquisado era composto de 16,48 anos como média de idade; percentual de 92,6% de cor parda ou preta; 70,37% tinham frequentado entre a 5ª série do Ensino Fundamental I e a 9ª série do Ensino Fundamental II; 44,44% faziam uso de bebidas alcoólicas diuturnamente; 40,74% apresentaram sintomas depressivos; 25,92% apresentaram histórico de ideação suicida, e 11,11% já tinham tentado suicídio. Os pesquisados com problemas de uso de substâncias psicoativas enfrentam um alto risco simultâneo de saúde mental, agravante que pode incorrer em situação de vida mais difícil com problemas sociais difusos, um quadro de saúde precário, prognosticando adversidades gerais. Dessa forma, é alarmante a situação desses adolescentes, que é uma amostra do submundo periférico das cidades, denotando a urgência de ações de saúde pública e do Estado. 2 Roxo caso i sociodemográficos ii fumo drogas iii iv 1648 16 48 16,4 idade 926 92 6 92,6 preta 7037 70 37 70,37 ª II 4444 44 44,44 diuturnamente 4074 40 74 40,74 depressivos 2592 25 25,92 1111 11 11,11 suicídio mental difusos precário gerais forma cidades Estado 164 1 4 16, 9 92, 703 7 3 70,3 444 44,4 407 40,7 259 25,9 111 11,1 70, 44, 40, 25, 11,

ABSTRACT. The objective was to evaluate the effect of probiotic consortium technology (PCT) on the performance of Penaeus vannamei juveniles in the biofloc system in a short time. The experiment had four treatments with four replicates. In each experimental unit, 35 animals (3.15 ± 0.53 g and 7.80 ± 0.54 cm) were stocked in a biofloc system for 35 days. The treatments were: control - control without probiotic; PCT1 - probiotic in the diet (3 mL kg-1) and water (0.5 ppm - three times a week); PCT2 - probiotic in the diet (3 mL kg-1) and water (1 ppm - daily), and PCT3 - probiotic in the water (1 ppm - daily). For water quality and Vibrio, no significant differences were observed among treatments (P > 0.05). Regarding the zootechnical performance, the treatments with the probiotic promoted higher final biomass, biomass gain, and a more efficient feed conversion rate (P < 0.05). The performance improvement promoted by the probiotic may be related to increased concentrations of amylases, chymotrypsin, and lipases in the hepatopancreas (P < 0.05). It was concluded that PCT2 promoted the best zootechnical performance of P. vannamei during the grow-out phase in the biofloc system.

Resumo Este estudo analisou o efeito da variação do rendimento, da desigualdade na distribuição do mesmo, da privação relativa e severa, das qualificações académicas, do emprego por profissões, da concentração da população em regiões urbanas, do envelhecimento da população, da incidência do uso de drogas e da imigração sobre a variação verificada, em Portugal, em onze grupos de crimes. Os resultados obtidos apontam para efeitos das qualificações académicas sobre os crimes registados contra a propriedade, contra a vida e integridade física e de condução, bem como para efeitos do produto interno bruto por residente, da idade média da população, das profissões, da urbanização, da desigualdade na distribuição do rendimento e da imigração.

Abstract This study analysed the effect of variations in income and inequality of income distribution, relative and severe poverty, academic qualifications,employment by occupation, concentration of the population in urban areas, ageing population, incidence of drug use and immigration on 11 groups of crimes in Portugal. The results showed the effects of academic qualifications on crimes against property, life and physical integrity and driving offences and the effects of gross domestic product per resident, the average age of the population, occupation, urbanisation, inequality in the distribution of income and immigration.

Resumen Este estudio analizó el efecto de la variación del rendimiento y de la desigualdad en su distribución, de la privación relativa y severa, de las cualificaciones académicas, del empleo por profesiones, de la concentración de la populación en regiones urbanas, del envejecimiento de la populación, de la incidencia del uso de drogas y de la inmigración sobre la variación verificada, en Portugal, en once grupos de crímenes. Los resultados obtenidos apuntan para efectos de las cualificaciones académicas sobre los crímenes registrados contra la propiedad, contra la vida e integridad física, y de conducción, así como para efectos del producto interno bruto por residente, de la edad promedio de la populación, de las profesiones, de la urbanización, de la desigualdad en la distribución del rendimiento y de la inmigración.

Résumé Cette étude analyse l’effet de la variation du revenu, de l’inégalité de la répartition de ce dernier, de la privation relative et sévère, des qualifications académiques, de l’emploi par professions, de la concentration de la population en régions urbaines, du vieillissement de la population, de l’incidence de la consommation de drogues et de l’immigration sur la variation constatée, au Portugal, sur onze groupes de crimes. Les résultats obtenus indiquent que les qualifications académiques ont des effets sur les crimes contre la propriété, contre la vie et l’intégrité physique et en rapport avec la conduite, tout comme le produit intérieur brut par résident, l’âge moyen de la population, les professions, l’urbanisation, l’inégalité dans la répartition du revenu et de l’immigration en ont aussi.

Abstract Introduction: The SARS-CoV-2 pandemic was a challenge for health authorities, both for health care systems, hospitals and health professionals. Objective: To describe emergency surgery in the SARS-CoV-2 pandemic. Material and methods: Retrospective, descriptive, observational study of patients with surgical pathologies in the Emergency Department from August to November 2020. Results: In 385 patients, with an average age of 50 years, the most frequent reason for consultation was pain in the epigastrium (21.3%), followed by yellowing of the skin and mucous membranes (18.7%) and rectal bleeding (16.8%). The evolution time averages 3 days. A total of 151 (39%) surgical interventions were performed, of which the most frequent were cholecystectomy (46.3%) and appendectomy (18.5%), 11 percutaneous treatments (2.8%) and 24 (6.2%) endoscopic treatments; 199 (51.7%) patients were treated conservatively. Among the post-surgical complications, surgical site infection was most frequently found in 38.4% and intra-abdominal collection in 37%. Of all patients received and admitted to the service, 32 (8.31%) were COVID-19 positive and during their hospital stay, 4 (12.5%) presented complications that included postoperative hemorrhage in two patients, mesenteric ischemia on one occasion and septic shock at pulmonary baseline. We had 1.2% of deaths. Conclusions: The average age of the patients was 50 years. The most frequent reason for consultation was epigastrium pain. Cholecystectomy was the most common surgery and the most common complication was surgical site infection. 1.2% deaths were recorded.

Resumen Introducción: La pandemia por SARS-CoV-2, constituyó un reto para las autoridades sanitarias, tanto para los sistemas de atención médica, hospitales y profesionales de la salud. Objetivo: Describir los cuadros quirúrgicos de urgencias, en la pandemia SARS-CoV-2. Material y método: Estudio retrospectivo, descriptivo, observacional de pacientes portadores de patologías quirúrgicas del servicio de Emergencias en los meses de agosto a noviembre 2020. Resultados: n 385 pacientes, con edad promedio de 50 años, el motivo de consulta más frecuente fue el dolor en epigastrio (21,3%), seguido de coloración amarillenta de piel y mucosas (18,7%) y rectorragia (16,8%). El tiempo de evolución en promedio de 3 días. Se realizaron 151 (39%) intervenciones quirúrgicas, de las cuales la más frecuentes fueron la colecistectomía (46,3%) y la apendicectomía (18,5%), 11 tratamientos percutáneos (2,8%) y 24 (6,2%) tratamientos endoscópicos; 199 (51,7%) pacientes se trataron de manera conservadora. Entre las complicaciones post quirúrgicas se constató con mayor frecuencia infección del sitio quirúrgico en un 38,4% y la colección intraabdominal 37%. De todos los pacientes recibidos e internados en el servicio 32 (8,31%) resultaron ser COVID-19 positivo y durante su estancia hospitalaria, presentaron complicaciones 4 (12,5%) que incluyeron hemorragia postquirúrgica en dos pacientes, isquemia mesentérica en una oportunidad y shock séptico a punto de partida pulmonar. Tuvimos 1,3% de óbitos. Conclusiones: La edad promedio de los pacientes fue de 50 años. El motivo de consulta más frecuente fue el dolor epigástrico. La colecistectomía fue la cirugía más frecuente y la complicación más común fue la infección del sitio quirúrgico. Se registraron 1,2% de óbitos. Palabras claves: Pandemia. Urgencias Quirúrgicas. SARS-CoV-2.

Classes of Recommendation Class I: Conditions for which there is conclusive evidence and, failing that, general agreement that a given procedure is safe and useful/effective. Class II: Conditions for which there is conflicting evidence and/or a divergence of opinion about the safety and usefulness/efficacy of a procedure. Class IIa: Weight or evidence/opinion in favor of the procedure. Most approve. Class IIb: Safety and usefulness/efficacy less well established, with divergence of opinions. Class III: Conditions for which there is evidence and/or general agreement that a procedure is not useful/effective and, in some cases, may be harmful. Levels of Evidence Level A: Data derived from multiple large, concordant randomized trials and/or robust meta-analyses of randomized trials. Level B: Data derived from less robust meta-analyses, from a single randomized trial and/or from observational studies. Level C: Data derived from consensus opinion of experts. I usefuleffective useful effective II andor usefulnessefficacy usefulness efficacy IIa evidenceopinion approve IIb established opinions III cases harmful A large metaanalyses meta analyses B metaanalyses, analyses, studies C experts

Classes de Recomendação Classe I: Condições para as quais há evidências conclusivas e, na sua falta, consenso geral de que o procedimento é seguro e útil/eficaz. Classe II: Condições para as quais há evidências conflitantes e/ou divergência de opinião sobre a segurança e utilidade/eficácia do procedimento. Classe IIa: Peso ou evidência/opinião a favor do procedimento. A maioria aprova. Classe IIb: Segurança e utilidade/eficácia menos estabelecidas, havendo opiniões divergentes. Classe III: Condições para as quais há evidências e/ou consenso de que o procedimento não é útil/eficaz e, em alguns casos, pode ser prejudicial. Níveis de Evidência Nível A: Dados obtidos a partir de múltiplos estudos randomizados de bom porte, concordantes e/ou de metanálise robusta de estudos randomizados. Nível B: Dados obtidos a partir de metanálise menos robusta, a partir de um único estudo randomizado e/ou de estudos observacionais. Nível C: Dados obtidos de opiniões consensuais de especialistas. I falta útileficaz útil eficaz II eou utilidadeeficácia utilidade eficácia IIa evidênciaopinião evidência aprova IIb estabelecidas divergentes III casos prejudicial porte B observacionais C especialistas

Introduction: Elderly patients have higher rates of morbidity and mortality during hospitalizations, diagnostic and surgical procedures. In order to improve the quality of care for the elderly, the APOIO (Preoperative Assessment of Elderly and Care Guidance) protocol was created, a tool to measure the risks of surgical complications. Objective: To evaluate the impact of APOIO on several outcomes, in order to validate it as a useful vehicle in the prevention of perioperative complications in elderly patients with fractures. Method: Retrospective cross-sectional study through review of 218 medical records of elderly patients hospitalized for fractures, and with surgical indication, having collected data on sex, age, reason for hospitalization, type of fracture, indication or not of surgical treatment, evaluation or not by APOIO, indication or not of ICU in the postoperative period, length of ICU stay, total length of hospitalization, immediate outcome and outcome within 30 days after the operation. Result: It was found that the application of APOIO was associated with a 70% reduction in the chances of death during hospitalization (p=0.040), length of stay in the ICU (p&lt;0.001) and total length of hospital stay (p = 0.010). There was also a trend towards a reduction in the death rate within 30 days of the postoperative period (p = 0.117). Conclusion: The application of the APOIO tool reduces the length of hospitalization, optimizes indication and length of stay in the ICU and, also, reduces the risk of death in elderly people undergoing surgical treatment for fractures.

Introdução: Pacientes idosos apresentam maior morbidade e mortalidade em internamentos hospitalares, procedimentos diagnósticos e cirúrgicos. Buscando melhorar a qualidade assistencial aos idosos foi criado o protocolo APOIO (Avaliação Pré-Operatória de Idosos e Orientação de cuidados), ferramenta para mensurar os riscos de complicações cirúrgicas. Objetivo: Avaliar o impacto do APOIO sobre vários desfechos, a fim de validá-lo como veículo útil na prevenção de complicações perioperatórias em idosos com fraturas. Método: Pesquisa retrospectiva transversal por meio de revisão de 218 prontuários de pacientes idosos internados por fraturas, e com indicação cirúrgica, tendo sido coletados dados sobre sexo, idade, motivo do internamento, tipo de fratura, indicação ou não de tratamento cirúrgico, avaliação ou não pela APOIO, indicação ou não de UTI no pós-operatório, duração do internamento em UTI, duração total do internamento, desfecho imediato e desfecho em 30 dias após a operação. Resultado: Foi constatado que a aplicação do APOIO foi associada à redução de 70% nas chances de óbito durante o internamento (p = 0,040), ao tempo de permanência em UTI (p &lt;0,001) e ao tempo total de internamento hospitalar (p = &nbsp;0,010). Observou-se ainda tendência à redução na taxa de óbitos em 30 dias do pós-operatório (p = 0,117). Conclusão: A aplicação da ferramenta APOIO reduz tempo de internamento, otimiza indicação e tempo de permanência em UTI e ainda diminui o risco de óbito de idosos submetidos a tratamentos cirúrgicos de fraturas.

Abstract Pancreatic neuroendocrine neoplasms (panNENs) have been historically regarded as rare, but their incidence has raised more than 6-fold over the last 3 decades, mostly owing to improvement in the detection of small asymptomatic tumours with imaging. Early detection and proper classification and staging are essential for the prognosis and management of panNENs. Histological evaluation is mandatory in all patients for the diagnosis of panNEN. Regarding localization and staging, multiphasic contrast-enhanced computer tomography is considered the imaging study of choice. Nevertheless, several other diagnostic modalities might present complementary information that can help in diagnosis and staging optimization: magnetic resonance imaging, somatostatin receptor imaging using positron emission tomography in combination with computed tomography (PET/CT), PET/CT with fluorodeoxyglucose (18F-FDG), and endoscopic ultrasound. Approximately 10%of panNENs are due to an inherited syndrome, which includes multiple endocrine neoplasia type 1, von Hippel-Lindau disease, neurofibromatosis type 1 (NF-1), tuberous sclerosis complex, and Mahvash disease. In this review, the Portuguese Pancreatic Club summarizes the classification, diagnosis, and staging of panNENs, with a focus on imaging studies. It also summarizes the characteristics and particularities of panNENs associated with inherited syndromes.

Resumo As neoplasias neuroendócrinas pancreáticas (panNENs) são historicamente consideradas raras, embora a sua incidência tenha aumentado mais de 6 vezes nas últimas três décadas, principalmente devido à otimização do diagnóstico de tumores pequenos e assintomáticos em exames de imagem. A deteção precoce, a classificação e o estadiamento adequados são essenciais para o prognóstico e abordagem dos panNENs. A avaliação histológica é obrigatória em todos os doentes para o diagnóstico de panNENs. Para a localização e estadiamento, a TC multifásica com contraste é considerada o estudo de imagem de eleição. Contudo, várias outras modalidades diagnósticas podem apresentar informações complementares que podem auxiliar no diagnóstico e na otimização do estadiamento: ressonância magnética, PET/CT dos receptores da somatostatina, PET/CT [1⁸F]FDG e ecoendoscopia. Aproximadamente 10% dos panNENs estão relacionados com síndromes hereditários, que incluem neoplasia endócrina múltipla tipo 1 (MEN1), doença de von Hippel-Lindau (VHL), neurofibromatose tipo 1 (NF1), complexo de esclerose tuberosa (TSC) e doença de Mahvash. Neste artigo, o Clube Português de Pâncreas aborda a classificação, diagnóstico e estadiamento de panNENs, com foco nos estudos de imagem, bem como resume as características e particularidades dos panNENs associados aos síndromes hereditários.

RESUMO Estudos sobre a utilização de águas salobras na irrigação de espécies ornamentais ainda são escassos, principalmente considerando aspectos qualitativos das plantas. Portanto, o presente estudo teve como objetivo identificar a tolerância à salinidade e caracterizar as respostas espectrais foliares de espécies ornamentais herbáceas na fase de produção de mudas para comercialização. O experimento foi realizado no período de dezembro de 2020 a fevereiro de 2021, em casa de vegetação, em Fortaleza - Ceará, Brasil. O experimento foi conduzido em delineamento de blocos casualizados, em parcelas subdivididas, sendo as parcelas compostas por níveis de salinidade da água de irrigação (0,5; 2,0; 4,0; 6,0 e 8,0 dS m-1), e as subparcelas pelas espécies Catharanthus roseus, Celosia cristata, Celosia plumosa e Chrysanthemum coronarium, com quatro repetições. Foram avaliadas produção de matéria seca, análise sensorial visual, tolerância à salinidade e respostas espectrais foliares. A qualidade visual foi mantida até 2,0 dS m-1 para a espécie Chrysanthemum coronarium e até 4,0 dS m-1 para as espécies Celosia cristata, Celosia plumosa e Catharanthus roseus, sendo as especies classificadas como moderadamente tolerantes nas respectivas salinidades. A salinidade provocou alterações notórias nas respostas espectrais foliares, principalmente na região do visível. escassos plantas Portanto comercialização 202 2021 vegetação Ceará Brasil casualizados subdivididas 0,5 05 0 5 (0,5 20 2 40 4 60 6 6, 80 8 8, m1, m1 m 1 , m-1) roseus cristata repetições seca 2, m- 4, salinidades visível 0, (0, (0 (

ABSTRACT Studies on using brackish water for the irrigation of ornamental species are still scarce, mainly considering qualitative aspects of the plants. Therefore, the present study aimed to identify salt tolerance and characterize leaf spectral responses of herbaceous ornamental species at the stage of commercial seedling production. The research was carried out from December 2020 to February 2021, under greenhouse conditions, in Fortaleza - Ceará, Brazil. The experiment was conducted in a randomized block design with split plots, with main plots consisting of irrigation-water salinity levels (0.5, 2.0, 4.0, 6.0, and 8.0 dS m-1), and subplots by the species Catharanthus roseus, Celosia cristata, Celosia plumosa, and Chrysanthemum coronarium, with four replications. The evaluation parameters were dry mass production, visual sensory analysis, salt tolerance, and leaf spectral responses. Plant visual quality was maintained up to 2.0 dS m-1 for Chrysanthemum coronarium and 4.0 dS m-1 for Celosia cristata, Celosia plumosa, and Catharanthus roseus, which were classified as moderately tolerant at those respective salinity levels. Salinity caused noticeable changes in leaf spectral responses, especially in the visible region. scarce plants Therefore production 202 2021 conditions Ceará Brazil irrigationwater 0.5, 05 0 5 (0.5 20 2 40 4 60 6 6.0 80 8 8. m1, m1 m 1 , m-1) roseus cristata plumosa replications analysis 2. m- 4. region 0.5 (0. 6. 0. (0 (