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ABSTRACT Cobalt (Co) and molybdenum (Mo) are essential elements with a fundamental role in biological nitrogen fixation in legumes. Vitamins such as thiamine, despite being required in small quantities, influence plant growth. This study aimed to assess the efficiency of different doses of thiamine applied as seed treatment, combined or not with Co and Mo, in enhancing the development of soybean crops. The experiment was conducted in a greenhouse according to a randomized block design with a 6 × 2 factorial arrangement, comprising six thiamine doses (0, 10, 25, 50, 100, and 200 mg kg-1) in the presence or absence of Co and Mo at the recommended rate of 100 mL ha-1. At 40 days after sowing, plants were analyzed for root length, root dry weight, shoot length, shoot dry weight, nodule number, and nodule dry weight. Principal component analysis showed that combined application of Co and Mo with thiamine was negatively associated with all variables and that the thiamine doses most positively associated with the analyzed variables were 50 and 200 mg kg-1. In treatments containing thiamine alone, there was a linear direct relationship between thiamine dose and nodule dry weight. Root and shoot lengths and dry weights were highest in plants treated with thiamine only at a dose of 122 mg kg-1. Application of Co and Mo combined with thiamine via seed treatment does not promote the development of soybean crops. Thiamine application is a promising treatment to increase shoot length, root dry weight, and nodule dry weight in soybean. (Co (Mo legumes quantities growth crops arrangement 0, 0 (0 10 25 20 kg1 kg 1 kg-1 ha1. ha1 ha 1. ha-1 4 sowing length number 5 kg1. alone 12 ( kg- ha-

https://doi.org/10.5935/1806-6690.20250010

Defoliation and nitrogen fertilization on the physiological quality of soybean seeds
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Aguiar, Viviane Cabrera Baptista de

; Fernandes, Marcio Alves

; Zuffo, Alan Mario

; Ratke, Rafael Felippe

; Aguilera, Jorge González

; Silva, Tiago Roque Benetoli da

; Alves, Charline Zaratin

Revista Ciência Agronômica

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2024, Volume 55 elocation e20238757

Abstract: En | Text: En | PDF: En

ABSTRACT Stress caused by defoliation can compromise the physiological quality of soybean seeds. However, there is evidence that the application of nitrogen (N) can be an alternative to reduce the qualitative losses in seeds caused by defoliating insects. The objective of this study was to evaluate the effectiveness of topdressing N fertilization in improving the physiological quality of soybean seeds from plants subjected to artificial defoliation. The experimental design was a randomized block arranged in a 2×4 factorial scheme with four replicates. The treatments consisted of two levels of defoliation (33 and 66%) and four doses of N (0, 50, 100, and 150 kg ha-1), using urea (45% N), applied two days after defoliation. Artificial defoliation was performed during the R3 stage by removing one (33%) and two leaflets (66%) from each trifoliate leaf under field conditions. At stage R5.1, leaf area was quantified, and after harvesting, germination, emergence, length, total dry mass, electrical conductivity, total protein content, mass of 1000 seeds, and tetrazolium (vigor and viability) tests were carried out. It was concluded that increasing the defoliation from 33 to 66% impaired the physiological quality of soybean seeds. The use of nitrogen fertilization for coverage after defoliation at the beginning of the reproductive phase cannot minimize qualitative losses in seeds.

https://doi.org/10.5935/1806-6690.20230066

Evidence of validity of the Risk Self-Medication Questionnaire focused on Health Literacy
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Barreto, Márcio Adriano Fernandes

; Negreiros, Francisca Diana da Silva

; Cestari, Virna Ribeiro Feitosa

; Sampaio, Helena Alves de Carvalho

; Moreira, Thereza Maria Magalhães

Revista Brasileira de Enfermagem

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2024, Volume 77 N. 3 elocation e20230386

Abstract: Es Pt En | Text: Es Pt En | PDF: Es | PDF: Pt | PDF: En

https://doi.org/10.1590/0034-7167-2023-0386

CONSTRUCTION AND VALIDITY OF AN ITEM BANK ON RISK SELF-MEDICATION
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Barreto, Márcio Adriano Fernandes

; Negreiros, Francisca Diana da Silva

; Cestari, Virna Ribeiro Feitosa

; Sampaio, Helena Alves de Carvalho

; Moreira, Thereza Maria Magalhães

Texto & Contexto - Enfermagem

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2024, Volume 33 elocation e20230169

Abstract: Es Pt En | Text: Es Pt En | PDF: Es | PDF: Pt | PDF: En

RESUMEN Objetivo: construir un banco de ítems para medir el riesgo de automedicación y evaluar su validez de contenido. Método: estudio metodológico realizado de mayo a octubre de 2022, con dos fases: 1) elaboración del banco de ítems a la luz de la alfabetización en medicamentos y la Teoría del Comportamiento Planificado a partir de una revisión del alcance; y 2) validez de contenido por veintidós expertos en salud. Se calcularon el Índice de Validez de Contenido, el Content Validity Ratio, la prueba exacta binomial para muestras pequeñas y el coeficiente de correlación intraclase. Resultados: la elaboración de los ítems del constructo Automedicación de Riesgo se basó en una amplia revisión de publicaciones nacionales e internacionales solidificadas en el área de la salud. Las definiciones fueron aprobadas por los jueces, con sus respectivos dominios. En la primera versión, el banco contenía 136 artículos. Se realizaron dos rondas de análisis con jueces, que resultaron en la eliminación de 87 ítems. La versión final presentó 49 ítems, distribuidos en tres dominios: alfabetización en medicina; Intención del comportamiento; y Comportamiento. El Índice de Validez de Contenido total fue de 0,89, con excelente confiabilidad (0,964). Hubo desacuerdo significativo en la atribución de puntuaciones entre los jueces (p>0,05) en algunos ítems. Conclusión: el banco de artículos tiene un contenido satisfactorio. Se recomienda someterse a un análisis semántico y posterior validez de la estructura interna.

RESUMO Objetivo: construir um banco de itens para mensuração da automedicação de risco e realizar sua validação de conteúdo. Método: estudo metodológico realizado no período de maio a outubro 2022, com duas fases: 1) elaboração do banco de itens, à luz do letramento em medicamentos e Teoria do Comportamento Planejado, a partir de revisão de escopo e 2) validação de conteúdo, por vinte e dois especialistas da saúde. Calculou-se o Índice de Validade de Conteúdo, Content Validity Ratio, teste exato binomial para amostras pequenas e coeficiente de correlação intraclasse. Resultados: a elaboração dos itens do constructo Automedicação de Risco foi fundamentada na ampla revisão de publicações nacionais e internacionais solidificadas na área da saúde. As definições foram aprovadas pelos juízes, com seus respectivos domínios. Na primeira versão, o banco continha 136 itens; foram realizadas duas rodadas de análises com juízes, que resultaram na remoção de 87 itens. A versão final apresentou 49 itens, distribuídos em três domínios: Letramento em medicamentos, Intenção do comportamento e Comportamento. O Índice de Validade de Conteúdo total foi de 0,89, com confiabilidade excelente (0,964). Houve discordância significativa na atribuição da pontuação entre os juízes (p>0,05) em alguns itens. Conclusão: o banco de itens apresenta conteúdo satisfatório. Recomenda-se passar por análise semântica e posterior validação da estrutura interna.

ABSTRACT Objective: to construct an item bank to measure risk self-medication and assess its content validity. Method: this is a methodological study carried out from May to October 2022, with two phases: 1) item bank elaboration in the light of medication literacy and Theory of Planned Behavior based on a scoping review; and 2) content validity by twenty-two health experts. The Content Validity Index, Content Validity Ratio, binomial exact test for small samples and intraclass correlation coefficient were calculated. Results: Risk Self-Medication construct item elaboration was based on a broad review of solidified national and international publications in the health area. The definitions were approved by judges, with their respective domains. In the first version, the bank contained 136 items. Two rounds of analysis were carried out with judges, which resulted in the removal of 87 items. The final version presented 49 items, distributed across three domains: Medication literacy; Behavioral intention; and Behavior. The total Content Validity Index was 0.89, with excellent reliability (0.964). There was significant disagreement in the attribution of scores among judges (p>0.05) in some items. Conclusion: the item bank has satisfactory content. It is recommended to undergo semantic analysis and subsequent structure validity.

https://doi.org/10.1590/1980-265x-tce-2023-0169en

X-rays for determination of papaya seeds viability Xrays X rays
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Nogueira, Graziely Alves

; Xavier, Gabriela Fernandes

; Silva, Tiago Roque Benetoli

; Bacchetta, Gianluigi

; Torres, Salvador Barros

; Pereira, Marcio Dias

; Dutra, Alek Sandro

; Alves, Charline Zaratin

Revista Ciência Agronômica

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2024, Volume 55 elocation e20238712

Abstract: En | Text: En | PDF: En

ABSTRACT This study investigated the effectiveness of using the X-ray technique to assess the viability of papaya seeds. The X-ray images were performed in eight replicates of 25 seeds, placed on transparent acrylic plates on double-sided adhesive tape, previously identified, and then submitted to radiation in X-ray equipment "HP Faxitron". After exposure to X-ray radiation, the seeds were submitted to the germination test in rolls of germitest paper and kept in a germination chamber at 20-30 °C for 30 days. Seedlings were photographed and evaluated as normal seedlings, abnormal and non-germinated seeds. Afterward, the X-ray images and the seedlings from the same seeds were visually compared, and the X-ray images clearly showed seeds with and without internal filling. All abnormal seedlings were full seeds; therefore, X-ray images were not able to separate normal and abnormal. A 100% accuracy was verified by comparing the X-ray images and their respective seedlings, full seeds originated normal or abnormal seedlings, and empty seeds corresponded to non-germinated seeds. Therefore, using X-ray images is a promising technique to identify the viability of papaya seeds. The automated analysis of X-ray images is a simple, fast, and efficient technique to provide information on seed viability and generate parameters related to their germination capacity. Xray X ray 2 doublesided double sided tape identified HP Faxitron. Faxitron . Faxitron" 2030 20 20-3 C 3 days nongerminated non germinated Afterward compared filling therefore 100 Therefore simple fast capacity 203 20- 10 1

https://doi.org/10.5935/1806-6690.20240021

Evidence of validity of the Risk Self-Medication Questionnaire focused on Health Literacy SelfMedication Self Medication
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Barreto, Márcio Adriano Fernandes

; Negreiros, Francisca Diana da Silva

; Cestari, Virna Ribeiro Feitosa

; Sampaio, Helena Alves de Carvalho

; Moreira, Thereza Maria Magalhães

Revista Brasileira de Enfermagem

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2024, Volume 77 N. 3 elocation e20230386

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objectives: to analyze the validity evidence of the internal structure of the Risk Self-Medication Questionnaire Focused on Health Literacy. Methods: a psychometric study with 499 adults. The internal structure was assessed with exploratory and confirmatory factor analysis to prove the adjustment. Internal consistency was measured by composite reliability and McDonald’s omega coefficient (ω). Results: the parameters revealed a model of 35 items distributed across four factors, explaining 56% of the total variance, with factor loadings ranging from 0.31 to 0.85 and adequate communalities. Accuracy (0.79<ORION<0.98), representativeness (0.89<FDI<0.99), sensitivity (1.92<SR<7.07), factor hope (88.3%< EPTD<97.9%), replicability (0.82<H-Latent<H-observed<0.87) and reliability (ω=0.87) were adequate. The composite reliability ranged from 0.840 to 0.910. Furthermore, good model fit was achieved (TLI = 0.99; CFI = 0.99; GFI = 0.95; RMSEA = 0.02 and RMSR = 0.05). Conclusions: an instrument was obtained with good evidence of structural validity for measuring self-medication. Objectives SelfMedication Self Medication Literacy Methods 49 adults adjustment McDonalds McDonald s ω. ω . (ω) Results 3 factors 56 variance 031 0 31 0.3 085 85 0.8 communalities 0.79<ORION<0.98, 079ORION098 ORION 0.79<ORION<0.98 , 79 98 (0.79<ORION<0.98) 0.89<FDI<0.99, 089FDI099 FDI 0.89<FDI<0.99 89 99 (0.89<FDI<0.99) 1.92<SR<7.07, 192SR707 SR 1.92<SR<7.07 1 92 7 07 (1.92<SR<7.07) 88.3%< 883 88 (88.3% EPTD<97.9%, EPTD979 EPTD EPTD<97.9% 97 9 EPTD<97.9%) 0.82<HLatent<Hobserved<0.87 082HLatentHobserved087 HLatentHobserved 0.82<H Latent<H observed<0.87 82 H Latent observed 87 (0.82<H-Latent<H-observed<0.87 ω=0.87 ω087 (ω=0.87 0840 840 0.84 0910 910 0.910 Furthermore TLI 0.99 099 0.95 095 95 002 02 0.0 0.05. 005 0.05 05 0.05) Conclusions selfmedication. selfmedication self medication. medication self-medication 4 (ω 5 03 0. 08 8 079ORION09 0.79<ORION<0.9 (0.79<ORION<0.98 089FDI09 0.89<FDI<0.9 (0.89<FDI<0.99 192SR70 1.92<SR<7.0 (1.92<SR<7.07 88.3% (88.3 EPTD97 EPTD<97.9 HLatent Hobserved 0.82<HLatent<Hobserved<0.8 082HLatentHobserved08 082H LatentH observed087 observed<0.8 (0.82<H-Latent<H-observed<0.8 ω=0.8 ω08 (ω=0.8 084 84 091 91 0.91 0.9 09 00 079ORION0 0.79<ORION<0. (0.79<ORION<0.9 089FDI0 0.89<FDI<0. (0.89<FDI<0.9 192SR7 1.92<SR<7. (1.92<SR<7.0 88.3 (88. EPTD9 EPTD<97. 0.82<HLatent<Hobserved<0. 082HLatentHobserved0 observed08 observed<0. (0.82<H-Latent<H-observed<0. ω=0. ω0 (ω=0. 079ORION 0.79<ORION<0 (0.79<ORION<0. 089FDI 0.89<FDI<0 (0.89<FDI<0. 192SR 1.92<SR<7 (1.92<SR<7. 88. (88 EPTD<97 0.82<HLatent<Hobserved<0 082HLatentHobserved observed0 observed<0 (0.82<H-Latent<H-observed<0 ω=0 (ω=0 0.79<ORION< (0.79<ORION<0 0.89<FDI< (0.89<FDI<0 1.92<SR< (1.92<SR<7 (8 EPTD<9 0.82<HLatent<Hobserved< observed< (0.82<H-Latent<H-observed< ω= (ω= 0.79<ORION (0.79<ORION< 0.89<FDI (0.89<FDI< 1.92<SR (1.92<SR< ( EPTD< 0.82<HLatent<Hobserved (0.82<H-Latent<H-observed (0.79<ORION (0.89<FDI (1.92<SR

RESUMEN Objetivos: analizar la evidencia de validez de la estructura interna del Cuestionario de Automedicación de Riesgos Enfocado a la Alfabetización en Salud. Métodos: estudio psicométrico, con 499 adultos. La estructura interna fue evaluada con análisis factorial exploratorio y confirmatorio para comprobar el ajuste. La consistencia interna se midió mediante la confiabilidad compuesta y el coeficiente omega de McDonald (ω). Resultados: los parámetros revelaron un modelo de 35 ítems distribuidos en cuatro factores, explicando el 56% de la varianza total, con cargas factoriales que oscilaron entre 0,31 y 0,85 y comunalidades adecuadas. Los indicadores precisión (0,79<ORION<0,98), representatividad (0,89<FDI<0,99), sensibilidad (1,92<SR<7,07), factor esperanza (88,3%< EPTD<97,9%), replicabilidad (0,82<H-Latente<H -observado<0,87) y la confiabilidad (ω=0,87) fueron adecuadas. La confiabilidad compuesta osciló entre 0,840 y 0,910. Además, se logró un buen ajuste del modelo (TLI = 0,99; CFI = 0,99; GFI = 0,95; RMSEA = 0,02 y RMSR = 0,05). Conclusiones: se obtuvo un instrumento con buena evidencia de validez estructural para medir la automedicación. Objetivos Salud Métodos psicométrico 49 adultos ω. ω . (ω) Resultados 3 factores 56 total 031 0 31 0,3 085 85 0,8 adecuadas 0,79<ORION<0,98, 079ORION098 ORION 0,79<ORION<0,98 , 79 98 (0,79<ORION<0,98) 0,89<FDI<0,99, 089FDI099 FDI 0,89<FDI<0,99 89 99 (0,89<FDI<0,99) 1,92<SR<7,07, 192SR707 SR 1,92<SR<7,07 1 92 7 07 (1,92<SR<7,07) 88,3%< 883 88 (88,3% EPTD<97,9%, EPTD979 EPTD EPTD<97,9% 97 9 EPTD<97,9%) 0,82<HLatente<H 082HLatenteH HLatenteH 0,82<H Latente<H 82 H Latente observado<0,87 observado087 observado 87 -observado<0,87 ω=0,87 ω087 (ω=0,87 0840 840 0,84 0910 910 0,910 Además TLI 0,99 099 0,95 095 95 002 02 0,0 0,05. 005 0,05 05 0,05) Conclusiones automedicación 4 (ω 5 03 0, 08 8 079ORION09 0,79<ORION<0,9 (0,79<ORION<0,98 089FDI09 0,89<FDI<0,9 (0,89<FDI<0,99 192SR70 1,92<SR<7,0 (1,92<SR<7,07 88,3% (88,3 EPTD97 EPTD<97,9 HLatente 082H LatenteH observado<0,8 observado08 -observado<0,8 ω=0,8 ω08 (ω=0,8 084 84 091 91 0,91 0,9 09 00 079ORION0 0,79<ORION<0, (0,79<ORION<0,9 089FDI0 0,89<FDI<0, (0,89<FDI<0,9 192SR7 1,92<SR<7, (1,92<SR<7,0 88,3 (88, EPTD9 EPTD<97, observado<0, observado0 -observado<0, ω=0, ω0 (ω=0, 079ORION 0,79<ORION<0 (0,79<ORION<0, 089FDI 0,89<FDI<0 (0,89<FDI<0, 192SR 1,92<SR<7 (1,92<SR<7, 88, (88 EPTD<97 observado<0 -observado<0 ω=0 (ω=0 0,79<ORION< (0,79<ORION<0 0,89<FDI< (0,89<FDI<0 1,92<SR< (1,92<SR<7 (8 EPTD<9 observado< -observado< ω= (ω= 0,79<ORION (0,79<ORION< 0,89<FDI (0,89<FDI< 1,92<SR (1,92<SR< ( EPTD< -observado (0,79<ORION (0,89<FDI (1,92<SR

RESUMO Objetivos: analisar as evidências de validade da estrutura interna do Questionário da Automedicação de Risco Focado no Letramento em Saúde. Métodos: estudo psicométrico, com 499 adultos. Avaliou-se a estrutura interna com análise fatorial exploratória e confirmatória para comprovar o ajuste. A consistência interna foi medida pela fidedignidade composta e pelo coeficiente ômega de McDonald (ω). Resultados: os parâmetros revelaram modelo de 35 itens distribuídos em quatro fatores, explicando 56% da variância total, com cargas fatoriais variando de 0,31 a 0,85 e comunalidades adequadas. Os indicadores precisão (0,79<ORION<0,98), representatividade (0,89<FDI<0,99), sensibilidade (1,92<SR<7,07), esperança do fator (88,3%<EPTD<97,9%), replicabilidade (0,82<H-Latente<H-observado<0,87) e confiabilidade (ω=0,87) foram adequados. A fidedignidade composta variou de 0,840 a 0,910. Além disso, alcançou-se bom ajuste do modelo (TLI = 0,99; CFI = 0,99; GFI = 0,95; RMSEA = 0,02; e RMSR = 0,05). Conclusões: obteve-se instrumento com boas evidências de validade de estrutura para mensuração da automedicação. Objetivos Saúde Métodos psicométrico 49 adultos Avaliouse Avaliou se ω. ω . (ω) Resultados 3 fatores 56 total 031 0 31 0,3 085 85 0,8 adequadas 0,79<ORION<0,98, 079ORION098 ORION 0,79<ORION<0,98 , 79 98 (0,79<ORION<0,98) 0,89<FDI<0,99, 089FDI099 FDI 0,89<FDI<0,99 89 99 (0,89<FDI<0,99) 1,92<SR<7,07, 192SR707 SR 1,92<SR<7,07 1 92 7 07 (1,92<SR<7,07) 88,3%<EPTD<97,9%, 883EPTD979 EPTD 88,3%<EPTD<97,9% 88 97 9 (88,3%<EPTD<97,9%) 0,82<HLatente<Hobservado<0,87 082HLatenteHobservado087 HLatenteHobservado 0,82<H Latente<H observado<0,87 82 H Latente observado 87 (0,82<H-Latente<H-observado<0,87 ω=0,87 ω087 (ω=0,87 adequados 0840 840 0,84 0910 910 0,910 disso alcançouse alcançou TLI 0,99 099 0,95 095 95 0,02 002 02 0,05. 005 0,05 05 0,05) Conclusões obtevese obteve automedicação 4 (ω 5 03 0, 08 8 079ORION09 0,79<ORION<0,9 (0,79<ORION<0,98 089FDI09 0,89<FDI<0,9 (0,89<FDI<0,99 192SR70 1,92<SR<7,0 (1,92<SR<7,07 883EPTD97 88,3%<EPTD<97,9 (88,3%<EPTD<97,9% HLatente Hobservado 0,82<HLatente<Hobservado<0,8 082HLatenteHobservado08 082H LatenteH observado087 observado<0,8 (0,82<H-Latente<H-observado<0,8 ω=0,8 ω08 (ω=0,8 084 84 091 91 0,91 0,9 09 0,0 00 079ORION0 0,79<ORION<0, (0,79<ORION<0,9 089FDI0 0,89<FDI<0, (0,89<FDI<0,9 192SR7 1,92<SR<7, (1,92<SR<7,0 883EPTD9 88,3%<EPTD<97, (88,3%<EPTD<97,9 0,82<HLatente<Hobservado<0, 082HLatenteHobservado0 observado08 observado<0, (0,82<H-Latente<H-observado<0, ω=0, ω0 (ω=0, 079ORION 0,79<ORION<0 (0,79<ORION<0, 089FDI 0,89<FDI<0 (0,89<FDI<0, 192SR 1,92<SR<7 (1,92<SR<7, 883EPTD 88,3%<EPTD<97 (88,3%<EPTD<97, 0,82<HLatente<Hobservado<0 082HLatenteHobservado observado0 observado<0 (0,82<H-Latente<H-observado<0 ω=0 (ω=0 0,79<ORION< (0,79<ORION<0 0,89<FDI< (0,89<FDI<0 1,92<SR< (1,92<SR<7 88,3%<EPTD<9 (88,3%<EPTD<97 0,82<HLatente<Hobservado< observado< (0,82<H-Latente<H-observado< ω= (ω= 0,79<ORION (0,79<ORION< 0,89<FDI (0,89<FDI< 1,92<SR (1,92<SR< 88,3%<EPTD< (88,3%<EPTD<9 0,82<HLatente<Hobservado (0,82<H-Latente<H-observado (0,79<ORION (0,89<FDI (1,92<SR 88,3%<EPTD (88,3%<EPTD< (88,3%<EPTD

https://doi.org/10.1590/0034-7167-2023-0386

CONSTRUCTION AND VALIDITY OF AN ITEM BANK ON RISK SELF-MEDICATION SELFMEDICATION SELF MEDICATION
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Barreto, Márcio Adriano Fernandes

; Negreiros, Francisca Diana da Silva

; Cestari, Virna Ribeiro Feitosa

; Sampaio, Helena Alves de Carvalho

; Moreira, Thereza Maria Magalhães

Texto & Contexto - Enfermagem

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2024, Volume 33 elocation e20230169

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

https://doi.org/10.1590/1980-265x-tce-2023-0169en

Os Intermetatarseum: A Rare Variation of Great Relevance
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Babinski, Marcio Antonio Passos, Germano Camargo Fleury Rodriguez, Beatriz Correa Padula, Eduardo de Oliveira Carrilho Fernandes, Rodrigo Mota Pacheco Feres-Junior, Roberto Pires, Lucas Alves Sarmento

International Journal of Morphology

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dec 2023, Volume 41 N. 6 Pages 1833 - 1836

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

SUMMARY: The os intermetatarseum is an accessory bone located in the foot, usually between the first 2 metatarsals and the cuneiform bone. It can be presented as free, articulated or in a fused fashion. It is a very unusual variation found in less than 13 % of the population. A 27-year-old patient presented to the emergency service due to an ankle lesion. Physical exam showed pain and limited range of motion while supporting partial load. Radiographic imaging showed a bony trace near the base of the first and second metatarsals, diagnosed as the os intermetatarseum. Formation of this supernumerary bone begins as a separate ossification center. Most cases are asymptomatic; however, compression of the deep peroneal nerve branches by the os intermetatarseum can lead to pain. Some authors suggest that the presence of this bone may cause hallux valgus. The intermetatarseum can lead to diagnostic confusion, mainly related to Lisfranc fracture. Its origin is still little understood.

RESUMEN: El os intermetatarseum es un hueso accesorio ubicado en el pie, generalmente entre los 2 primeros metatarsianos y el hueso cuneiforme. Puede presentarse de forma libre, articulada o fusionada. Es una variación muy inusual que se encuentra en menos del 13 % de la población. Paciente de 27 años que acude a urgencias por lesión en tobillo. El examen físico mostró dolor y rango de movimiento limitado mientras soportaba una carga parcial. Las imágenes radiológicas mostraron un rastro óseo cerca de la base del primer y segundo metatarsianos, diagnosticado como os intermetatarseum. La formación de este hueso supernumerario comienza como un centro de osificación separado. La mayoría de los casos son asintomáticos; sin embargo, la compresión de las ramas profundas del nervio fibular en el espacio intermetatarsiano puede provocar dolor. Algunos autores sugieren que la presencia de este hueso puede provocar hallux valgus. El hueso intermetatarsiano puede llevar a confusión diagnóstica, principalmente relacionada con la fractura de Lisfranc. Su origen aún es poco comprendido.

Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil
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LOUREDO, Brendo Vinicius Rodrigues

; CURADO, Maria Paula

; PENAFORT, Paulo Victor Mendes

; DE ARRUDA, José Alcides Almeida

; ABREU, Lucas Guimarães

; MESQUITA, Ricardo Alves

; PINTO-JÚNIOR, Décio dos Santos

; ABRAHÃO, Aline Corrêa

; ANDRADE, Bruno Augusto Benevenuto de

; AGOSTINI, Michelle

; MORAES, Renata Mendonça

; ANBINDER, Ana Lia

; DOURADO, Pedro Henrique Silva

; SANTOS, Teresa Cristina Ribeiro Bartholomeu dos

; PIRES, Fábio Ramoa

; BORDIGNON, Natalia Cristina Trentin

; GONDAK, Rogério Oliveira

; DE OLIVEIRA, Marcia Gaiger

; CARRARD, Vinicius Coelho

; MARTINS, Manoela Domingues

; SOUSA-NETO, Sebastião Silvério

; ARANTES, Diego Antônio Costa

; MENDONÇA, Elismauro Francisco

; CIESLAK-SANCHES, Silvia Roberta

; ANTUNES, Daniella Moraes

; AMARAL-SILVA, Gleyson Kleber do

; MANIERI, Patricia Rubia

; RAMALHO, Luciana Maria Pedreira

; DOS SANTOS, Jean Nunes

; LEONEL, Augusto César Leal da Silva

; PEREZ, Danyel Elias da Cruz

; VERHEUL, Hannah Carmem Carlos Ribeiro Silva

; BARROSO, Keila Martha Amorim

; RODRIGUES, Flávia Luiza Santos

; GONZAGA, Amanda Katarinny Goes

; FERNANDES, Romana Renery

; DE SOUZA, Lélia Batista

; SOUZA, Lucas Lacerda de

; PONTES, Flávia Sirotheau Corrêa

; PONTES, Hélder Antônio Rebelo

; SILVA, Caroline Alfaia

; CÂMARA, Jeconias

; LIBÓRIO-KIMURA, Tatiana Nayara

; SANTOS-SILVA, Alan Roger

; LOPES, Márcio Ajudarte

; ALMEIDA, Oslei Paes de

; ROMAÑACH, Mário José

; VARGAS, Pablo Agustin

Brazilian Oral Research

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2023, Volume 37 elocation e126

Abstract: En | Text: En | PDF: En

Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients’ histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil’s Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0126

10.

Monitoramento da carga viral de SARS-CoV-2 em águas residuais na cidade de Goiânia: epidemiologia baseada em esgoto e um sistema de alerta precoce para COVID-19 SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- Goiânia COVID19 COVID 19 COVID-1 SARS-CoV COVID1 1 COVID-
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Mendes, Geovana de Melo

; Estrela, Paulo Felipe Neves Souza Junior, Marcio Neres de Brito, Núbia Natália de Arruda, Andréa Fernandes Augusto, Matheus Ribeiro Claro, Ieda Carolina Mantovani Duran, Adriana Feliciano Alves Cabral, Aline Diniz Bueno, Rodrigo de Freitas Duarte, Gabriela Rodrigues Mendes

Química Nova

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oct 2022, Volume 45 N. 10 Pages 1197 - 1204

Abstract: Pt | Text: Pt | PDF: Pt

COVID-19 is currently the most critical disease in the world. Thus, several tools have been used in the last two years to contain the spread of SARS-CoV-2. In this perspective, Wastewater-Based Epidemiology (WBE) provides valuable data by including symptomatic, pre-symptomatic, and asymptomatic individuals and anticipating clinical cases. For 37 weeks, the SARS-CoV-2 viral load was monitored in sanitary sewage samples from Goiânia-Brazil. Through pre-concentration, extraction, and purification of viral RNA, followed by RT-qPCR, it was detected in 83.78% (31/37) of the weeks the presence of fragments of the genetic material SARS-CoV-2 with viral loads ranging from 105 to 108 genome copies L-1. The viral load in the wastewater samples was related to the clinical data of the municipality, demonstrating its ability to promote an Early Warning System (EWS). In early 2022, it was possible to predict the increase in clinical cases 3 weeks in advance and issue an alert note to the health authorities. Prevalence estimates ranged from 0.003 to 0.5% and showed good agreement with observed values. Thus, monitoring effluents become another essential tool that can help combat the pandemic’s advance, especially in countries with scarce resources. COVID19 COVID 19 COVID-1 world Thus SARSCoV2. SARSCoV2 SARSCoV SARS CoV 2. 2 perspective WastewaterBased Wastewater Based WBE (WBE symptomatic presymptomatic, presymptomatic pre pre-symptomatic SARS-CoV- GoiâniaBrazil. GoiâniaBrazil Goiânia Brazil. Brazil Goiânia-Brazil preconcentration, preconcentration concentration, concentration pre-concentration extraction RNA RTqPCR, RTqPCR RT qPCR, qPCR RT-qPCR 8378 83 78 83.78 31/37 3137 31 (31/37 10 L1. L1 L 1. 1 L-1 municipality EWS. EWS . (EWS) 2022 authorities 0003 0 003 0.00 05 5 0.5 values pandemics pandemic s resources COVID1 COVID- SARS-CoV 837 8 7 83.7 31/3 313 (31/3 L- (EWS 202 000 00 0.0 0. 83. 31/ (31/ 20 (31 (3 (

https://doi.org/10.21577/0100-4042.20170933

11.

Supernumerary Muscles in the Posterior Leg Compartment: a Case Report
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Postigo, Paulo Rogério Moritz da-Costa-Guimarães, Raquel Sangy Pires, Lucas Alves Sarmento Fernandes, Rodrigo Mota Pacheco Babinski, Marcio Antonio Manaia, Jorge Henrique Martins

International Journal of Morphology

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feb 2022, Volume 40 N. 1 Pages 75 - 78

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

SUMMARY: The leg muscles are organized in anterior, lateral and posterior compartments. The posterior compartment is usually divided in two layers: superficial and deep. The deep muscles of the posterior compartment of the leg are known to mainly plantar flexion and toes flexion. In comparison to the other leg compartments, variations of the posterior one are rare. These variants often involve the presence or absence of one or more muscles, and they have differences among origin and insertion, which leads to confusion between anatomists. We aim to describe a case of a male cadaver that possessed three supernumerary muscles in the lateral and posterior compartments of both legs: the peroneus quartus muscle and two accessory bellies of the flexor digitorum longus. This presentation seems to be very rare and scarcely reported in the literature. These variants have the potential of causing nervous or vascular compression, thus leading to tarsal tunnel syndrome or a symptomatic peroneus quartus. The clinical and surgical implications of this abnormal presentation is discussed.

RESUMEN: Los músculos de la pierna están organizados en compartimentos anterior, lateral y posterior. El compartimento posterior por lo general es dividido en dos capas: superficial y profunda. Se sabe que los músculos profundos del compartimento posterior de la pierna se caracterizan principalmente por participar de la flexión plantar y la flexión de los dedos de los pies. En comparación con los otros compartimentos de la pierna, las variaciones musculares en el compartimiento posterior son raras. Estas variantes suelen implicar la presencia o ausencia de uno o más músculos y presentan diferencias en el origen y en la inserción, lo que conduce a confusión entre los anatomistas. Nuestro objetivo fue describir el caso de un cadáver masculino que poseía tres músculos supernumerarios en los compartimentos lateral y posterior de ambas piernas: el músculo fibular cuarto y dos vientres accesorios del músculo flexor largo de los dedos. Esta presentación parece ser muy rara y escasamente reportada en la literatura. Estas variantes musculares tienen el potencial de causar compresión nerviosa o vascular, lo que conduce al síndrome del túnel del tarso o un cuarto músculo fibular sintomático. Se discuten las implicaciones clínicas y quirúrgicas de esta presentación anormal.

12.

Anatomia comparada de Clethra scabra Pers. (Clethraceae) em diferentes altitudes na Serra da Mantiqueira, Minas Gerais, Brasil
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Santos, Maria Luiza

; Ribeiro, Alessandra de Oliveira

; Castro, Evaristo Mauro de

; Miranda, Kaline Fernandes

; Lira, Marinês Ferreira Pires

; Pereira, Márcio Paulo

; Ferreira, Cassiana Alves

; Mori, Fabio Akira

Ciência Florestal

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sep 2021, Volume 31 N. 3 Pages 1407 - 1426

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Para verificar a influência da altitude na estrutura anatômica de folhas e do xilema secundário de galhos de indivíduos da espécie Clethra scabra Pers. (Clethraceae) ocorrentes na Serra da Mantiqueira, estado de Minas Gerais, realizaram-se coletas de amostras nas cotas altitudinais de 1500, 1700, 1900 e 2100 m (metros). As folhas e galhos coletados foram fixados e preparados seguindo procedimentos usuais de microtécnica vegetal. Procederam-se análises anatômicas quantitativas utilizando software de análise de imagem. As folhas de C. scabra são hipoestomáticas com epiderme trisseriada e tricomas estrelados, mesofilo dorsiventral, parênquima paliçádico com uma a duas camadas celulares e o parênquima esponjoso com quatro. A nervura central com xilema desenvolvido e o feixe vascular envolvido pela bainha esclerenquimática. Análises de variância (ANOVA) e teste de Scott-Knott demonstraram que as espessuras do limbo foliar, mesofilo e parênquima paliçádico não apresentaram diferenças estatísticas significativas entre as altitudes avaliadas. O xilema secundário apresentou diminuição no comprimento dos elementos de vaso com o aumento da altitude na cota de 2100 m e o diâmetro tangencial dos elementos de vaso aumentaram nas duas menores altitudes e depois reduziram. Índices de vulnerabilidade de Carlquist e de mesomorfia diminuíram ao longo do gradiente altitudinal. Comprimento e diâmetro das fibras diminuíram com elevação da altitude. Assim, a altitude influencia nas modificações anatômicas apresentadas por folhas e galhos de C. scabra, que podem ser relacionadas a sua plasticidade fenotípica em resposta às diferentes condições ambientais.

Abstract To verify the influence of altitude on the anatomical structure of leaves and the secondary xylem of branches of individuals of the species Clethra scabra Pers. (Clethraceae) occurring in the Serra da Mantiqueira, state of Minas Gerais, samples were collected at altitudes of 1500, 1700, 1900 and 2100 m (meters). The collected leaves and branches were fixed and prepared following usual plant microtechnical procedures. Quantitative anatomical analyzes were performed using image analysis software. The leaves of C. scabra are hypoestomatic with triseriate epidermis and stellate trichomes, dorsiventral mesophyll, palisade parenchyma with one to two cell layers and the spongeous parenchyma with four. The central rib with developed xylem and the vascular bundle involved by the sclerenchyma sheath. Analysis of variance (ANOVA) and Scott-Knott test demonstrated that the thickness of the leaf blade, mesophyll and palisade parenchyma did not present statistically significant differences between the evaluated altitudes. The secondary xylem showed a decrease in the length of the vessel elements with increasing altitude at the 2100 m elevation and the tangential diameter of the vessel elements increased at the two lowest altitudes and then reduced. The Carlquist and the mesomorphic vulnerability indices decreased along the altitudinal gradient. Fiber length and diameter decreased with increasing altitude. Thus, altitude influences the anatomical changes presented by leaves and branches of C. scabra, which can be related to its phenotypic plasticity in response to different environmental conditions.

https://doi.org/10.5902/1980509842333

13.

Stability of early anterior open bite treatment: a 2-year follow-up randomized clinical trial
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Dias, Flaviana Alves

; Oltramari, Paula Vanessa Pedron

; Almeida, Marcio Rodrigues de

; Conti, Ana Claúdia de Castro Ferreira

; Almeida, Renato Rodrigues de

; Fernandes, Thais Maria Freire

Brazilian Dental Journal

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jun 2021, Volume 32 N. 3 Pages 116 - 126

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Os objetivos do presente estudo foram comparar e avaliar a estabilidade do tratamento precoce da mordida aberta anterior (MAA) com diferentes dispositivos. A amostra inicial foi composta por 99 pacientes randomizados em quatro grupos experimentais: BS - esporões colados; CC - mentoneira; FPC - grade palatina fixa; RPC - grade palatina removível. Análise cefalométrica foi realizada para avaliar os dados do período inicial (T1), final do tratamento (T2) e 2 anos após tratamento (T3), sendo a variável overbite o desfecho principal. Em T3, após perdas de seguimento, haviam 63 indivíduos, sendo BS (n=15; overbite 0.19 mm; 11.54 anos; 10 Feminino (F)/5 Masculino (M)); CC (n=11; overbite -0.19 mm; 11.41 anos; 8 F/3 M); FPC (n=21; overbite 1.23 mm; 11.44 anos; 15 F/6 M) e; RPC (n=16; overbite 0.73 mm; 11.67 anos; 6 F/10 M). Comparações das alterações nas variáveis dentoesqueléticas e abandono de hábitos bucais deletérios durante o tempo de acompanhamento foram estatisticamente analisados com p<.05. Medidas esqueléticas lineares mandibulares e componentes verticais aumentaram gradualmente com a idade, principalmente com o surto de crescimento puberal e estabelecimento da dentição permanente no pós-tratamento. O overbite foi significantemente melhorado durante o tratamento, permanecendo estável com alterações positivas. A extrusão dos incisivos impactou na correção da MAA e estabilidade nos 4 grupos, que registraram uma melhora de 1.15 mm no pós-tratamento (T3-T2). Com suas limitações, todos dispositivos experimentais foram efetivos e mostraram resultados estáveis no tratamento precoce da MAA, sendo que a FPC apresentou a maior correção da MAA e o menor índice de desistência.

Abstract This 2-year-follow up study compared and evaluated the stability of early anterior open bite (AOB) treatment based on different appliances. Children from 7 to 10 years with Angle Class I, AOB larger than 1.0 mm and fully erupted maxillary and mandibular permanent central incisors were eligible. The initial sample was 99 patients distributed, by simple randomization, into four groups: BS (bonded spurs), CC (chincup), FPC (fixed palatal crib) and RPC (removable palatal crib). Cephalometric analysis was performed at baseline (T1), final (T2) and 2-year post-treatment (T3) by taking the overbite measurements as the main outcome. Blinding was possible to cephalometric analysis. At T3, with dropouts, there were 63 individuals, being BS (n=15; overbite 0.19 mm; 11.54 years; 10 female (F)/5 male (M)); CC (n=11; overbite -0.19 mm; 11.41 years; 8 F/3 M); FPC (n=21; overbite 1.23 mm; 11.44 years; 15 F/6 M) and; RPC (n=16; overbite 0.73 mm; 11.67 years; 6 F/10 M). Changes in dentoskeletal variables and breaking deleterious oral habits during the follow up were statically analyzed with p<.05. Mandibular skeletal linear measurements and vertical dental components have gradually increased with age, manly at pubertal growth spurt and at the establishment of permanent dentition after treatment. Incisor teeth extrusion had impact on AOB correction and stability in 4 groups, which recorded a 1.15 mm-improvement of overbite after treatment (T3-T2). The experimental appliances were effective with stable results, being FPC the device recorded the highest AOB correction and the lowest patient withdrawal rate.

https://doi.org/10.1590/0103-6440202103509 74 downloads

14.

Is restless legs syndrome in Parkinson disease patients associated with any specific factor?
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SOBREIRA-NETO, Manoel Alves

; PENA-PEREIRA, Márcio Alexandre

; SOBREIRA, Emmanuelle Silva Tavares

; CHAGAS, Marcos Hortes Nisihara

; ALMEIDA, Carlos Maurício Oliveira de

; FERNANDES, Regina Maria França

; TUMAS, Vitor

; ECKELI, Alan Luiz

Arquivos de Neuro-Psiquiatria

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jan 2021, Volume 79 N. 1 Pages 38 - 43

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: A síndrome das pernas inquietas, ou doença de Willis-Ekbom, é um transtorno caracterizado por sensações de desconforto associadas à necessidade de movimentar os membros inferiores. Nos pacientes com doença de Parkinson, a síndrome das pernas inquietas está associada a uma qualidade de vida inferior e sonolência excessiva. Em relação a outros fatores, resultados de diferentes estudos mostraram resultados controversos. Objetivo: Determinar os fatores associados à presença da síndrome das pernas inquietas nos pacientes com doença de Parkinson. Métodos: Um estudo transversal foi conduzido com 88 pacientes com doença de Parkinson, consecutivos, acompanhados em ambulatório especializado, durante 21 meses. Participantes passaram por uma entrevista clínica, avaliação por meio de escalas padronizadas (Escala de Sonolência de Epworth, Questionário de Qualidade de Vida da Doença de Parkinson, Índice de Qualidade de Sono de Pittsburgh, Escala de Gravidade Internacional da Síndrome das Pernas Inquietas) e videopolissonografia. Resultados: Do total de 88 participantes, 25 tinham síndrome das pernas inquietas. Na análise multivariada, a síndrome das pernas inquietas na doença de Parkinson esteve associada à perda de olfato, assim como à qualidade de vida e ao sono. Na análise univariada, a síndrome das pernas inquietas na doença de Parkinson ocorreu mais frequentemente em mulheres, com maior frequência de insônia, constipação e anosmia, do que no grupo sem síndrome das pernas inquietas. Conclusão: A síndrome das pernas inquietas é uma condição prevalente na doença de Parkinson e está associada a características específicas neste grupo de pacientes.

ABSTRACT Background: Restless legs syndrome or Willis-Ekbom disease is a disorder characterized by unpleasant sensations associated with the need to mobilize the lower limbs. In Parkinson disease patients, restless legs syndrome is associated with worse quality of life and excessive sleepiness. Regarding other factors, results of different studies are controversial. Objective: To determine the factors associated with the restless legs syndrome presence in Parkinson disease patients. Methods: A cross-sectional study was conducted in 88 consecutive Parkinson disease patients from the outpatient clinic for 21 months. Participants underwent a clinical interview, assessment based on standardized scales (Epworth Sleepiness Scale, Parkinson Disease Questionnaire - 39, Pittsburgh Sleep Quality Index, International Restless Legs Syndrome Study Group rating scale), and video-polysomnography. Results: Out of the 88 participants, 25 had restless legs syndrome. In the multivariate analysis, restless legs syndrome in Parkinson disease has been associated with the symptom of smell loss and quality of sleep and life. In the univariate analysis, restless legs syndrome in Parkinson disease has occurred more frequently in women with higher frequency of insomnia, constipation, and anosmia than in the group without restless legs syndrome. Conclusion: Restless legs syndrome is a prevalent condition in patients with Parkinson disease and is associated with specific characteristics in this group of patients.

https://doi.org/10.1590/0004-282x-anp-2020-0122 606 downloads

15.

Validation of the Brazilian Portuguese version of the Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire (RBDSQ-BR)
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PENA-PEREIRA, Márcio Alexandre

; SOBREIRA-NETO, Manoel Alves

; SOBREIRA, Emmanuelle

; CHAGAS, Marcos Hortes Nisihara

; OLIVEIRA, Daniel Sabino de

; RODRIGUES, Guilherme Riccioppo

; SOUZA, Carolina Pinto de

; ECKELI, Alan Luiz

; FERNANDES, Regina Maria França

; TUMAS, Vitor

Arquivos de Neuro-Psiquiatria

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oct 2020, Volume 78 N. 10 Pages 629 - 637

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: O diagnóstico do transtorno comportamental do sono REM (TCSREM) implica na realização da polissonografia (PSG), mas sua disponibilidade pode não ser suficiente. Portanto, meios clínicos para o diagnóstico podem ser úteis. Objetivo: Validar para a língua portuguesa falada no Brasil o questionário de triagem do TCSREM (QT-TCSREM) em pacientes portadores de doença de Parkinson (DP). Métodos: Uma amostra por conveniência composta de 69 indivíduos foi dividida em portadores de DP com TCSREM (n=50) e DP sem TCSREM (n=19) através de entrevista clínica detalhada e análise da PSG. Resultados: QT-TCSREM-BR apresentou consistência interna adequada (α de Cronbach=0,809) e, exceto pelo item 8, correlação item-total adequada. Reteste feito em uma segunda amostra (n=13, consecutivos) evidenciou concordância elevada para o escore total (coeficiente de correlação intraclasse, CCI=0,863) e aceitável para os itens 2, 3, 6.2, 6.3, 7 e 8 (K>0,60). Análise da curva característica de operação do receptor (COR) obteve uma área sob a curva de 0,728. O corte 4 permitiu o diagnóstico correto de 76,8% dos indivíduos e apresentou o melhor equilíbrio entre sensibilidade (84%) e especificidade (57,9%), com uma razão de verossimilhança de um resultado positivo (RV+) 2,0 e de um resultado negativo (RV-) 0,3. Os itens 2 e 6.2 obtiveram especificidade 84,2% e RV+ 3,2. Itens combinados 1+2+6,2, 2+6,1 e 6,1+6,2 aumentaram a especificidade para 94,7%, com RV+ variando de 6,1 até 7,6. Conclusões: O QT-TCSREM-BR é um instrumento confiável que pode ser útil para o diagnóstico do TCSREM em pacientes com DP no Brasil. O instrumento também é válido e pode auxiliar numa melhor seleção de casos a serem submetidos a uma avaliação mais detalhada ou até mesmo a uma análise de PSG.

ABSTRACT Introduction: A diagnosis of rapid eye movement sleep behavior disorder (RBD) currently requires confirmation with polysomnography (PSG). However, PSG may not be sufficiently available. In these situations, a clinical diagnostic measure might be useful. Objective: To validate the Brazilian Portuguese version of RBD screening questionnaire (RBDSQ) for patients with Parkinson’s disease (PD). Methods: Using detailed clinical interviews and PSG analysis (diagnostic gold standard), a convenience sample of 69 subjects was divided into the following subgroups: patients with PD and RBD (PD+RBD; n=50) and patients with PD alone (PD-RBD; n=19). Results: RBDSQ-BR showed adequate internal consistency (Cronbach’s α=0.809) and, except for item 8, adequate item-test correlation. The retest performed in a second sample (n=13, consecutive) showed high agreement for total score (intraclass correlation coefficient, ICC=0.863) and acceptable agreement for items 2, 3, 6.2, 6.3, 7, and 8 (K>0.60). The receiver operating characteristic (ROC) curve analysis had an area under the curve (AUC) of 0.728. A cut-off score of 4 enabled the correct diagnosis of 76.8% subjects and provided the best balance between sensitivity (84%) and specificity (57.9%), with a 2.0 likelihood ratio of a positive result (LR+) and a 0.3 likelihood ratio of a negative result (LR-). Items 2 and 6.2 had 84.2% specificity and 3.2 LR+. Combined items 1+2+6.2, 2+6.1, and 6.1+6.2 increased the specificity to 94.7%, with LR+ ranging from 6.1 to 7.6. Conclusions: RBDSQ-BR is a reliable instrument, which may be useful for RBD diagnosis of Brazilian patients with PD. The instrument is also valid and may help in a better selection of cases for a more detailed clinical evaluation or even PSG analysis.

https://doi.org/10.1590/0004-282x20200125 811 downloads

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Glossary and search help

You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.

For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

See below the complete list of search indexes that can be used:

Index code	Element
ti	article title
au	author
kw	article keywords
subject	subject (title words, abstract and keywords)
ab	abstract
ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

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