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1.
Incomplete recovery of the CD4+/CD8+ ratio is associated with the late introduction of antiretroviral therapy among people living with HIV infection CD4CD8 CDCD CD4 CD8 CD CD4+/CD8 CD4CD CD4+/CD
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Prates, Gabriela da Silva
; Monteiro, Mariana Amelia
; Oliveira, Éricka Constantinov
; Nascimento, Najara Ataide de Lima
; Veiga, Ana Paula Rocha
; Ferreira, Mauricio Domingues
; Polis, Thales José Bueno
; Caetano, Gabriela Prandi
; Soares, Beatriz Rodrigues Pellegrina
; Magri, Marcello Mihailenko Chaves
; Pereira, Luisa Oliveira
; Fonseca, Luiz Augusto Marcondes
; Alves, Wagner Silva
; Duarte, Alberto José da Silva
; Casseb, Jorge Simão do Rosário
.
ABSTRACT Despite being subject to lower AIDS-related mortality rates and having a higher life expectancy, patients with HIV are more prone to develop non-AIDS events. A low CD4+/CD8+ ratio during antiretroviral therapy identifies people with heightened immune senescence and increased risk of mortality. In clinical practice, finding determinants of a low CD4+/CD8+ ratio may be useful for identifying patients who require close monitoring due to an increased risk of comorbidities and death. We performed a prospective study on the evolution of the CD4+/CD8+ ratio in 60 patients infected with HIV (80% males), who were subjected to two different antiretroviral regimens: early and deferred therapy. The initial CD4+/CD8+ ratio was ≤1 for 70% of the patients in both groups. Older age, CD4+ cell count at inclusion, Nadir CD8+T-cell count, and Initial CD4+/CD8+ ratio ≤ 1 were risk factors for lack of ratio recovery. In the multivariate analysis, a CD4+/CD8+ ratio > 1 at the start of the treatment was found to be a determinant factor in maintaining a CD4+/CD8+ ratio > 1. The nadir CD4+T-cell count was lower in the deferred therapy group (p=0.004), and the last CD4+/CD8+ ratio ≤1 was not associated with comorbidities. Ratio recovery was not associated with the duration of HIV infection, time without therapy, or absence of AIDS incidence. A greater improvement was observed in patients treated early (p=0.003). In contrast, the slope of increase was slower in patients who deferred treatment. In conclusion, the increase in the CD4+/CD8+ ratio occurred mostly for patients undergoing early strategy treatment and its extension did not seem to be related to previous HIV-related factors. AIDSrelated expectancy nonAIDS non events CD4CD8 CDCD CD4 CD8 CD CD4+/CD8 practice death 6 80% 80 (80 males, males , males) regimens 70 groups age inclusion CD8+Tcell CD8Tcell CDTcell CD8+T T analysis CD4+Tcell CD4Tcell CD4+T p=0.004, p0004 p p=0.004 0 004 (p=0.004) infection incidence p=0.003. p0003 p=0.003 . 003 (p=0.003) contrast conclusion HIVrelated CD4CD CD4+/CD 8 (8 7 Tcell CD8T CDT CD4T p000 p=0.00 00 (p=0.004 (p=0.003 ( p00 p=0.0 (p=0.00 p0 p=0. (p=0.0 p=0 (p=0. p= (p=0 (p= (p
2.
Vaccination coverage, hesitancy and associated factors: a household survey of a cohort of children born in 2017 and 2018 in urban areas of state capital cities in the Brazilian Northeast
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Saavedra, Ramon da Costa
; Santiago, Martha Suely Itaparica de Carvalho
; Teixeira, Maria da Glória Lima Cruz
; Antunes, Maria Bernadete de Cerqueira
; Queiroz, Rejane Christine de Sousa
; Lima, Luisa Helena de Oliveira
; Ramos Jr, Alberto Novaes
; Ferreira, Anderson Fuentes
; Maciel, Adjoane Mauricio Silva
; Barbosa, Jaqueline Caracas
; França, Ana Paula
; Domingues, Carla Magda Allan Santos
; Moraes, José Cássio de
; Silva, Adriana Ilha da
; Ramos Jr., Alberto Novaes
; França, Ana Paula
; Oliveira, Andrea de Nazaré Marvão
; Boing, Antonio Fernando
; Domingues, Carla Magda Allan Santos
; Oliveira, Consuelo Silva de
; Maciel, Ethel Leonor Noia
; Guibu, Ione Aquemi
; Mirabal, Isabelle Ribeiro Barbosa
; Barbosa, Jaqueline Caracas
; Lima, Jaqueline Costa
; Moraes, José Cássio de
; Luhm, Karin Regina
; Caetano, Karlla Antonieta Amorim
; Lima, Luisa Helena de Oliveira
; Antunes, Maria Bernadete de Cerqueira
; Teixeira, Maria da Glória Lima Cruz
; Teixeira, Maria Denise de Castro
; Borges, Maria Fernanda de Sousa Oliveira
; Queiroz, Rejane Christine de Sousa
; Gurgel, Ricardo Queiroz
; Barata, Rita Barradas
; Azevedo, Roberta Nogueira Calandrini de
; Oliveira, Sandra Maria do Valle Leone de
; Teles, Sheila Araújo
; Gama, Silvana Granado Nogueira da
; Mengue, Sotero Serrate
; Simões, Taynãna César
; Nascimento, Valdir
; Araújo, Wildo Navegantes de
.
ABSTRACT Objective To estimate vaccination coverage and analyze sociodemographic factors associated with non-vaccination in children born in 2017 and 2018 in the state capitals of Northeast Brazil. Methods A household survey using cluster sampling was conducted from 2020-2022 to estimate vaccination coverage and hesitancy. Factors associated with non-vaccination were analyzed using logistic regression to calculate Odds Ratios (OR) and their Confidence Intervals (95%CI). Results Natal was the capital with the lowest vaccination coverage, below 75.0% for most immunizers. Teresina had rates equal to or greater than 90.0% for all vaccines. Among those interviewed, 99.1% (95%CI 98.9;99.3) believe that vaccines are important for health; 95.4% (95%CI 95.0;95.8) trust immunobiologicals and 79.6% (95%CI% 78.8;80.3) are not afraid of reactions. Belonging to the highest socioeconomic stratum (adjusted OR: 1.34 – 95%CI 1.20;1.50) was as a factor associated with non-vaccination. Conclusion Low coverage highlights the need for a better understanding of regional specificities and social inequalities.
RESUMO Objetivo Estimar a cobertura vacinal e analisar fatores sociodemográficos associados à não vacinação em crianças nascidas vivas em 2017 e 2018 nas capitais do Nordeste brasileiro. Métodos Realizou-se inquérito domiciliar com amostragem por conglomerados, entre 2020 e 2022, para estimar cobertura e hesitação vacinal. Fatores associados à não vacinação foram analisados usando-se regressão logística para calcular odds ratio (OR) e seus intervalos de confiança (IC95%). Resultados A capital com menores coberturas vacinais foi Natal, com < 75,0% para a maioria dos imunizantes; Teresina apresentou coberturas ≥ 90,0% em todos os imunizantes. Dos entrevistados, 99,1% (IC95% 98,9;99,3) acreditavam que vacinas são importantes para a saúde; 95,4% (IC95% 95,0;95,8) confiavam nos imunobiológicos distribuídos pelo governo; e 79,6% (IC95% 78,8;80,3) não tinham medo de reações adversas. Residir em estrato socioeconômico mais alto (OR ajustado: 1,34 – IC95% 1,20;1,50) foi fator associado à não vacinação. Conclusão As baixas coberturas destacam a necessidade de entender melhor as especificidades regionais e as desigualdades sociais.
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3.
Measles, mumps and rubella vaccination coverage in capitals and interior region municipalities of Northeast Brazil: a household survey in a cohort of children born in 2017 and 2018 Measles Brazil 201 20 2
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Maciel, Adjoane Mauricio Silva
; Ramos Jr, Alberto Novaes
; Ferreira, Anderson Fuentes
; Silva, Taynara Lais
; Domingues, Carla Magda Allan Santos
; Saavedra, Ramon da Costa
; Barbosa, Jaqueline Caracas
; França, Ana Paula
; Kerr, Ligia Regina Franco Sansigolo
; Teixeira, Maria da Gloria
; Moraes, José Cássio de
; Silva, Adriana Ilha da
; Ramos Jr., Alberto Novaes
; França, Ana Paula
; Oliveira, Andrea de Nazaré Marvão
; Boing, Antonio Fernando
; Domingues, Carla Magda Allan Santos
; Oliveira, Consuelo Silva de
; Maciel, Ethel Leonor Noia
; Guibu, Ione Aquemi
; Mirabal, Isabelle Ribeiro Barbosa
; Barbosa, Jaqueline Caracas
; Lima, Jaqueline Costa
; Moraes, José Cássio de
; Luhm, Karin Regina
; Caetano, Karlla Antonieta Amorim
; Lima, Luisa Helena de Oliveira
; Antunes, Maria Bernadete de Cerqueira
; Teixeira, Maria da Gloria
; Teixeira, Maria Denise de Castro
; Borges, Maria Fernanda de Sousa Oliveira
; Queiroz, Rejane Christine de Sousa
; Gurgel, Ricardo Queiroz
; Barata, Rita Barradas
; Azevedo, Roberta Nogueira Calandrini de
; Oliveira, Sandra Maria do Valle Leone de
; Teles, Sheila Araújo
; Gama, Silvana Granado Nogueira da
; Mengue, Sotero Serrate
; Simões, Taynãna César
; Nascimento, Valdir
; Araújo, Wildo Navegantes de
.
RESUMO Objetivo Analisar a cobertura vacinal contra sarampo, caxumba e rubéola em crianças até 24 meses de idade e os fatores associados à não vacinação em coorte de nascidos-vivos em 2017-2018, em capitais e municípios de grande porte populacional do interior do Nordeste brasileiro. Métodos Inquérito domiciliar populacional com análise de cobertura vacinal e fatores sociodemográficos por regressão logística. Resultados Em 12.137 crianças, cobertura vacinal de 79,3% (IC95% 76,5;81,8) e taxa de abandono de 10,6%. Associação à não vacinação: estrato socioeconômico A (OR-a 1,29; IC95% 1,10;1,50), residir no interior (OR-a 1,22; IC95% 1,07;1,39), não acesso ao Programa Bolsa Família (OR-a 1,19; IC95% 1,05;1,34), renda familiar ≤ R$ 1.000,00 (OR-a 1,17; IC95% 1,03;1,31), mãe sem trabalho remunerado (OR-a 1,28; IC95% 1,15;1,42), > 1 filho por mãe (OR-a 1,12; IC95% 1,08;1,17), sem caderneta de vacinação (OR-a 10,69; IC95% 6,27;18,20). Conclusão Baixa cobertura e alta taxa de abandono vacinal em capitais e municípios do interior do Nordeste. sarampo 2 nascidosvivos nascidos vivos 20172018, 20172018 2017 2018, 2018 2017-2018 brasileiro logística 12137 12 137 12.13 793 79 3 79,3 IC95 IC (IC95 76,581,8 765818 76,5 81,8 76 5 81 8 76,5;81,8 106 10 6 10,6% ORa OR 1,29 129 29 1,101,50, 110150 1,10 1,50 , 50 1,10;1,50) 1,22 122 22 1,071,39, 107139 1,07 1,39 07 39 1,07;1,39) 1,19 119 19 1,051,34, 105134 1,05 1,34 05 34 1,05;1,34) R 100000 000 00 1.000,0 1,17 117 17 1,031,31, 103131 1,03 1,31 03 31 1,03;1,31) 1,28 128 28 1,151,42, 115142 1,15 1,42 15 42 1,15;1,42) 1,12 112 1,081,17, 108117 1,08 08 1,08;1,17) 10,69 1069 69 6,2718,20. 6271820 6,27 18,20 . 27 18 20 6,27;18,20) 2017201 201 2017-201 1213 13 12.1 7 79, IC9 (IC9 581 76,581, 76581 765 76, 818 81, 76,5;81, 10,6 1,2 101 1,101,50 11015 110 1,1 150 1,5 1,10;1,50 071 1,071,39 10713 107 1,0 139 1,3 0 1,07;1,39 11 051 1,051,34 10513 105 134 1,05;1,34 10000 1.000, 031 1,031,31 10313 103 131 1,03;1,31 151 1,151,42 11514 115 142 1,4 4 1,15;1,42 081 1,081,17 10811 108 1,08;1,17 2718 6,2718,20 627182 627 6,2 1820 18,2 6,27;18,20 201720 2017-20 121 12. (IC 58 76,581 7658 76,5;81 10, 1, 1,101,5 1101 1,10;1,5 1,071,3 1071 1,07;1,3 1,051,3 1051 1,05;1,3 1000 1.000 1,031,3 1031 1,03;1,3 1,151,4 1151 14 1,15;1,4 1,081,1 1081 1,08;1,1 271 6,2718,2 62718 62 6, 182 18, 6,27;18,2 20172 2017-2 76,58 76,5;8 1,101, 1,10;1, 1,071, 1,07;1, 1,051, 1,05;1, 100 1.00 1,031, 1,03;1, 1,151, 1,15;1, 1,081, 1,08;1, 6,2718, 6271 6,27;18, 2017- 76,5; 1,101 1,10;1 1,071 1,07;1 1,051 1,05;1 1.0 1,031 1,03;1 1,151 1,15;1 1,081 1,08;1 6,2718 6,27;18 1,10; 1,07; 1,05; 1. 1,03; 1,15; 1,08; 6,271 6,27;1 6,27;
ABSTRACT Objective To analyze measles, mumps, and rubella vaccination coverage among children up to 24 months old and factors associated with non-vaccination in a 2017−2018 live birth cohort, in state capitals and large interior region cities in Northeast Brazil. Methods Population-based survey analyzing vaccination coverage and sociodemographic factors through logistic regression. Results For 12,137 children, vaccination coverage was 79.3% (95%CI 76.5;81.8), and the dropout rate was 10.6%. Association with non-vaccination: socioeconomic stratum A (OR-a 1.29; 95%CI 1.10;1.50), living in the interior region (OR-a 1.22; 95%CI 1.07;1.39), no access to the Bolsa Família Program (OR-a 1.19, 95%CI 1.05;1.34), family income ≤BRL 1,000 (OR-a 1.17, 95%CI 1.03;1.31), mother not working (OR-a 1.28, 95%CI 1.15;1.42), >1 child per mother (OR-a 1.12, 95%CI 1.08;1.17), and no vaccination card (OR-a 10.69, 95%CI 6.27;18.20). Conclusion Low vaccination coverage and a high dropout rate in state capitals and municipalities in the interior region of Northeast Brazil. measles mumps 2 nonvaccination non 20172018 2017 2018 2017−201 cohort Brazil Populationbased Population based regression 12137 12 137 12,13 793 79 3 79.3 95CI CI 95 76.581.8, 765818 76.5 81.8 , 76 5 81 8 76.5;81.8) 106 10 6 10.6% ORa OR 1.29 129 1 29 1.101.50, 110150 1.10 1.50 50 1.10;1.50) 1.22 122 22 1.071.39, 107139 1.07 1.39 07 39 1.07;1.39) 119 19 1.19 1.051.34, 105134 1.05 1.34 05 34 1.05;1.34) BRL 1000 000 1,00 117 17 1.17 1.031.31, 103131 1.03 1.31 03 31 1.03;1.31) 128 28 1.28 1.151.42, 115142 1.15 1.42 15 42 1.15;1.42) > 112 1.12 1.081.17, 108117 1.08 08 1.08;1.17) 1069 69 10.69 6.2718.20. 6271820 6.27 18.20 . 27 18 20 6.27;18.20) 2017201 201 2017−20 1213 13 12,1 7 79. 9 581 76.581.8 76581 765 76. 818 81. 76.5;81.8 10.6 1.2 101 1.101.50 11015 110 1.1 150 1.5 1.10;1.50 071 1.071.39 10713 107 1.0 139 1.3 0 1.07;1.39 11 051 1.051.34 10513 105 134 1.05;1.34 100 00 1,0 031 1.031.31 10313 103 131 1.03;1.31 151 1.151.42 11514 115 142 1.4 4 1.15;1.42 081 1.081.17 10811 108 1.08;1.17 2718 6.2718.20 627182 627 6.2 1820 18.2 6.27;18.20 201720 2017−2 121 12, 58 76.581. 7658 76.5;81. 10. 1. 1.101.5 1101 1.10;1.5 1.071.3 1071 1.07;1.3 1.051.3 1051 1.05;1.3 1, 1.031.3 1031 1.03;1.3 1.151.4 1151 14 1.15;1.4 1.081.1 1081 1.08;1.1 271 6.2718.2 62718 62 6. 182 18. 6.27;18.2 20172 2017− 76.581 76.5;81 1.101. 1.10;1. 1.071. 1.07;1. 1.051. 1.05;1. 1.031. 1.03;1. 1.151. 1.15;1. 1.081. 1.08;1. 6.2718. 6271 6.27;18. 76.58 76.5;8 1.101 1.10;1 1.071 1.07;1 1.051 1.05;1 1.031 1.03;1 1.151 1.15;1 1.081 1.08;1 6.2718 6.27;18 76.5; 1.10; 1.07; 1.05; 1.03; 1.15; 1.08; 6.271 6.27;1 6.27;
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4.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
; Linzmeier, Adelita M.
; Calor, Adolfo R.
; Garda, Adrian A.
; Kury, Adriano B.
; Fernandes, Agatha C.S.
; Agudo-Padrón, Aisur I.
; Akama, Alberto
; Silva Neto, Alberto M. da
; Burbano, Alejandro L.
; Menezes, Aleksandra
; Pereira-Colavite, Alessandre
; Anichtchenko, Alexander
; Lees, Alexander C.
; Bezerra, Alexandra M.R.
; Domahovski, Alexandre C.
; Pimenta, Alexandre D.
; Aleixo, Alexandre L.P.
; Marceniuk, Alexandre P.
; Paula, Alexandre S. de
; Somavilla, Alexandre
; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
; Santos, Aline B. dos
; Tassi, Aline D.
; Aragão, Allan C.
; Santos, Allan P.M.
; Migotto, Alvaro E.
; Mendes, Amanda C.
; Cunha, Amanda
; Chagas Júnior, Amazonas
; Sousa, Ana A.T. de
; Pavan, Ana C.
; Almeida, Ana C.S.
; Peronti, Ana L.B.G.
; Henriques-Oliveira, Ana L.
; Prudente, Ana L.
; Tourinho, Ana L.
; Pes, Ana M.O.
; Carmignotto, Ana P.
; Wengrat, Ana P.G. da Silva
; Dornellas, Ana P.S.
; Molin, Anamaria Dal
; Puker, Anderson
; Morandini, André C.
; Ferreira, André da S.
; Martins, André L.
; Esteves, André M.
; Fernandes, André S.
; Roza, André S.
; Köhler, Andreas
; Paladini, Andressa
; Andrade, Andrey J. de
; Pinto, Ângelo P.
; Salles, Anna C. de A.
; Gondim, Anne I.
; Amaral, Antonia C.Z.
; Rondón, Antonio A.A.
; Brescovit, Antonio
; Lofego, Antônio C.
; Marques, Antonio C.
; Macedo, Antonio
; Andriolo, Artur
; Henriques, Augusto L.
; Ferreira Júnior, Augusto L.
; Lima, Aurino F. de
; Barros, Ávyla R. de A.
; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
; Santos, Bernardo F.
; Ferraz, Bernardo R.
; Rosa, Brunno B.
; Sampaio, Brunno H.L.
; Bellini, Bruno C.
; Clarkson, Bruno
; Oliveira, Bruno G. de
; Corrêa, Caio C.D.
; Martins, Caleb C.
; Castro-Guedes, Camila F. de
; Souto, Camilla
; Bicho, Carla de L.
; Cunha, Carlo M.
; Barboza, Carlos A. de M.
; Lucena, Carlos A.S. de
; Barreto, Carlos
; Santana, Carlos D.C.M. de
; Agne, Carlos E.Q.
; Mielke, Carlos G.C.
; Caetano, Carlos H.S.
; Flechtmann, Carlos H.W.
; Lamas, Carlos J.E.
; Rocha, Carlos
; Mascarenhas, Carolina S.
; Margaría, Cecilia B.
; Waichert, Cecilia
; Digiani, Celina
; Haddad, Célio F.B.
; Azevedo, Celso O.
; Benetti, Cesar J.
; Santos, Charles M.D. dos
; Bartlett, Charles R.
; Bonvicino, Cibele
; Ribeiro-Costa, Cibele S.
; Santos, Cinthya S.G.
; Justino, Cíntia E.L.
; Canedo, Clarissa
; Bonecker, Claudia C.
; Santos, Cláudia P.
; Carvalho, Claudio J.B. de
; Gonçalves, Clayton C.
; Galvão, Cleber
; Costa, Cleide
; Oliveira, Cléo D.C. de
; Schwertner, Cristiano F.
; Andrade, Cristiano L.
; Pereira, Cristiano M.
; Sampaio, Cristiano
; Dias, Cristina de O.
; Lucena, Daercio A. de A.
; Manfio, Daiara
; Amorim, Dalton de S.
; Queiroz, Dalva L. de
; Queiroz, Dalva L. de
; Colpani, Daniara
; Abbate, Daniel
; Aquino, Daniel A.
; Burckhardt, Daniel
; Cavallari, Daniel C.
; Prado, Daniel de C. Schelesky
; Praciano, Daniel L.
; Basílio, Daniel S.
; Bená, Daniela de C.
; Toledo, Daniela G.P. de
; Takiya, Daniela M.
; Fernandes, Daniell R.R.
; Ament, Danilo C.
; Cordeiro, Danilo P.
; Silva, Darliane E.
; Pollock, Darren A.
; Muniz, David B.
; Gibson, David I.
; Nogueira, David S.
; Marques, Dayse W.A.
; Lucatelli, Débora
; Garcia, Deivys M.A.
; Baêta, Délio
; Ferreira, Denise N.M.
; Rueda-Ramírez, Diana
; Fachin, Diego A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Pádua, Diego G. de
; Barbosa, Diego N.
; Dolibaina, Diego R.
; Amaral, Diogo C.
; Chandler, Donald S.
; Maccagnan, Douglas H.B.
; Caron, Edilson
; Carvalho, Edrielly
; Adriano, Edson A.
; Abreu Júnior, Edson F. de
; Pereira, Edson H.L.
; Viegas, Eduarda F.G.
; Carneiro, Eduardo
; Colley, Eduardo
; Eizirik, Eduardo
; Santos, Eduardo F. dos
; Shimbori, Eduardo M.
; Suárez-Morales, Eduardo
; Arruda, Eliane P. de
; Chiquito, Elisandra A.
; Lima, Élison F.B.
; Castro, Elizeu B. de
; Orlandin, Elton
; Nascimento, Elynton A. do
; Razzolini, Emanuel
; Gama, Emanuel R.R.
; Araujo, Enilma M. de
; Nishiyama, Eric Y.
; Spiessberger, Erich L.
; Santos, Érika C.L. dos
; Contreras, Eugenia F.
; Galati, Eunice A.B.
; Oliveira Junior, Evaldo C. de
; Gallardo, Fabiana
; Hernandes, Fabio A.
; Lansac-Tôha, Fábio A.
; Pitombo, Fabio B.
; Dario, Fabio Di
; Santos, Fábio L. dos
; Mauro, Fabio
; Nascimento, Fabio O. do
; Olmos, Fabio
; Amaral, Fabio R.
; Schunck, Fabio
; Godoi, Fábio S. P. de
; Machado, Fabrizio M.
; Barbo, Fausto E.
; Agrain, Federico A.
; Ribeiro, Felipe B.
; Moreira, Felipe F.F.
; Barbosa, Felipe F.
; Silva, Fenanda S.
; Cavalcanti, Fernanda F.
; Straube, Fernando C.
; Carbayo, Fernando
; Carvalho Filho, Fernando
; Zanella, Fernando C.V.
; Jacinavicius, Fernando de C.
; Farache, Fernando H.A.
; Leivas, Fernando
; Dias, Fernando M.S.
; Mantellato, Fernando
; Vaz-de-Mello, Fernando Z.
; Gudin, Filipe M.
; Albuquerque, Flávio
; Molina, Flavio B.
; Passos, Flávio D.
; Shockley, Floyd W.
; Pinheiro, Francielly F.
; Mello, Francisco de A.G. de
; Nascimento, Francisco E. de L.
; Franco, Francisco L.
; Oliveira, Francisco L. de
; Melo, Francisco T. de V.
; Quijano, Freddy R.B.
; Salles, Frederico F.
; Biffi, Gabriel
; Queiroz, Gabriel C.
; Bizarro, Gabriel L.
; Hrycyna, Gabriela
; Leviski, Gabriela
; Powell, Gareth S.
; Santos, Geane B. dos
; Morse, Geoffrey E.
; Brown, George
; Mattox, George M.T.
; Zimbrão, Geraldo
; Carvalho, Gervásio S.
; Miranda, Gil F.G.
; Moraes, Gilberto J. de
; Lourido, Gilcélia M.
; Neves, Gilmar P.
; Moreira, Gilson R.P.
; Montingelli, Giovanna G.
; Maurício, Giovanni N.
; Marconato, Gláucia
; Lopez, Guilherme E.L.
; Silva, Guilherme L. da
; Muricy, Guilherme
; Brito, Guilherme R.R.
; Garbino, Guilherme S.T.
; Flores, Gustavo E.
; Graciolli, Gustavo
; Libardi, Gustavo S.
; Proctor, Heather C.
; Gil-Santana, Helcio R.
; Varella, Henrique R.
; Escalona, Hermes E.
; Schmitz, Hermes J.
; Rodrigues, Higor D.D.
; Galvão Filho, Hilton de C.
; Quintino, Hingrid Y.S.
; Pinto, Hudson A.
; Rainho, Hugo L.
; Miyahira, Igor C.
; Gonçalves, Igor de S.
; Martins, Inês X.
; Cardoso, Irene A.
; Oliveira, Ismael B. de
; Franz, Ismael
; Fernandes, Itanna O.
; Golfetti, Ivan F.
; S. Campos-Filho, Ivanklin
; Oliveira, Ivo de S.
; Delabie, Jacques H.C.
; Oliveira, Jader de
; Prando, Jadila S.
; Patton, James L.
; Bitencourt, Jamille de A.
; Silva, Janaina M.
; Santos, Jandir C.
; Arruda, Janine O.
; Valderrama, Jefferson S.
; Dalapicolla, Jeronymo
; Oliveira, Jéssica P.
; Hájek, Jiri
; Morselli, João P.
; Narita, João P.
; Martin, João P.I.
; Grazia, Jocélia
; McHugh, Joe
; Cherem, Jorge J.
; Farias Júnior, José A.S.
; Fernandes, Jose A.M.
; Pacheco, José F.
; Birindelli, José L.O.
; Rezende, José M.
; Avendaño, Jose M.
; Duarte, José M. Barbanti
; Ribeiro, José R. Inácio
; Mermudes, José R.M.
; Pujol-Luz, José R.
; Santos, Josenilson R. dos
; Câmara, Josenir T.
; Teixeira, Joyce A.
; Prado, Joyce R. do
; Botero, Juan P.
; Almeida, Julia C.
; Kohler, Julia
; Gonçalves, Julia P.
; Beneti, Julia S.
; Donahue, Julian P.
; Alvim, Juliana
; Almeida, Juliana C.
; Segadilha, Juliana L.
; Wingert, Juliana M.
; Barbosa, Julianna F.
; Ferrer, Juliano
; Santos, Juliano F. dos
; Kuabara, Kamila M.D.
; Nascimento, Karine B.
; Schoeninger, Karine
; Campião, Karla M.
; Soares, Karla
; Zilch, Kássia
; Barão, Kim R.
; Teixeira, Larissa
; Sousa, Laura D. do N.M. de
; Dumas, Leandro L.
; Vieira, Leandro M.
; Azevedo, Leonardo H.G.
; Carvalho, Leonardo S.
; Souza, Leonardo S. de
; Rocha, Leonardo S.G.
; Bernardi, Leopoldo F.O.
; Vieira, Letícia M.
; Johann, Liana
; Salvatierra, Lidianne
; Oliveira, Livia de M.
; Loureiro, Lourdes M.A. El-moor
; Barreto, Luana B.
; Barros, Luana M.
; Lecci, Lucas
; Camargos, Lucas M. de
; Lima, Lucas R.C.
; Almeida, Lucia M.
; Martins, Luciana R.
; Marinoni, Luciane
; Moura, Luciano de A.
; Lima, Luciano
; Naka, Luciano N.
; Miranda, Lucília S.
; Salik, Lucy M.
; Bezerra, Luis E.A.
; Silveira, Luis F.
; Campos, Luiz A.
; Castro, Luiz A.S. de
; Pinho, Luiz C.
; Silveira, Luiz F.L.
; Iniesta, Luiz F.M.
; Tencatt, Luiz F.C.
; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
; Araújo, Marcel S. de
; Monné, Marcela L.
; Labruna, Marcelo B.
; Santis, Marcelo D. de
; Duarte, Marcelo
; Knoff, Marcelo
; Nogueira, Marcelo
; Britto, Marcelo R. de
; Melo, Marcelo R.S. de
; Carvalho, Marcelo R. de
; Tavares, Marcelo T.
; Kitahara, Marcelo V.
; Justo, Marcia C.N.
; Botelho, Marcia J.C.
; Couri, Márcia S.
; Borges-Martins, Márcio
; Felix, Márcio
; Oliveira, Marcio L. de
; Bologna, Marco A.
; Gottschalk, Marco S.
; Tavares, Marcos D.S.
; Lhano, Marcos G.
; Bevilaqua, Marcus
; Santos, Marcus T.T.
; Domingues, Marcus V.
; Sallum, Maria A.M.
; Digiani, María C.
; Santarém, Maria C.A.
; Nascimento, Maria C. do
; Becerril, María de los A.M.
; Santos, Maria E.A. dos
; Passos, Maria I. da S. dos
; Felippe-Bauer, Maria L.
; Cherman, Mariana A.
; Terossi, Mariana
; Bartz, Marie L.C.
; Barbosa, Marina F. de C.
; Loeb, Marina V.
; Cohn-Haft, Mario
; Cupello, Mario
; Martins, Marlúcia B.
; Christofersen, Martin L.
; Bento, Matheus
; Rocha, Matheus dos S.
; Martins, Maurício L.
; Segura, Melissa O.
; Cardenas, Melissa Q.
; Duarte, Mércia E.
; Ivie, Michael A.
; Mincarone, Michael M.
; Borges, Michela
; Monné, Miguel A.
; Casagrande, Mirna M.
; Fernandez, Monica A.
; Piovesan, Mônica
; Menezes, Naércio A.
; Benaim, Natalia P.
; Reategui, Natália S.
; Pedro, Natan C.
; Pecly, Nathalia H.
; Ferreira Júnior, Nelson
; Silva Júnior, Nelson J. da
; Perioto, Nelson W.
; Hamada, Neusa
; Degallier, Nicolas
; Chao, Ning L.
; Ferla, Noeli J.
; Mielke, Olaf H.H.
; Evangelista, Olivia
; Shibatta, Oscar A.
; Oliveira, Otto M.P.
; Albornoz, Pablo C.L.
; Dellapé, Pablo M.
; Gonçalves, Pablo R.
; Shimabukuro, Paloma H.F.
; Grossi, Paschoal
; Rodrigues, Patrícia E. da S.
; Lima, Patricia O.V.
; Velazco, Paul
; Santos, Paula B. dos
; Araújo, Paula B.
; Silva, Paula K.R.
; Riccardi, Paula R.
; Garcia, Paulo C. de A.
; Passos, Paulo G.H.
; Corgosinho, Paulo H.C.
; Lucinda, Paulo
; Costa, Paulo M.S.
; Alves, Paulo P.
; Roth, Paulo R. de O.
; Coelho, Paulo R.S.
; Duarte, Paulo R.M.
; Carvalho, Pedro F. de
; Gnaspini, Pedro
; Souza-Dias, Pedro G.B.
; Linardi, Pedro M.
; Bartholomay, Pedro R.
; Demite, Peterson R.
; Bulirsch, Petr
; Boll, Piter K.
; Pereira, Rachel M.M.
; Silva, Rafael A.P.F.
; Moura, Rafael B. de
; Boldrini, Rafael
; Silva, Rafaela A. da
; Falaschi, Rafaela L.
; Cordeiro, Ralf T.S.
; Mello, Ramon J.C.L.
; Singer, Randal A.
; Querino, Ranyse B.
; Heleodoro, Raphael A.
; Castilho, Raphael de C.
; Constantino, Reginaldo
; Guedes, Reinaldo C.
; Carrenho, Renan
; Gomes, Renata S.
; Gregorin, Renato
; Machado, Renato J.P.
; Bérnils, Renato S.
; Capellari, Renato S.
; Silva, Ricardo B.
; Kawada, Ricardo
; Dias, Ricardo M.
; Siewert, Ricardo
; Brugnera, Ricaro
; Leschen, Richard A.B.
; Constantin, Robert
; Robbins, Robert
; Pinto, Roberta R.
; Reis, Roberto E. dos
; Ramos, Robson T. da C.
; Cavichioli, Rodney R.
; Barros, Rodolfo C. de
; Caires, Rodrigo A.
; Salvador, Rodrigo B.
; Marques, Rodrigo C.
; Araújo, Rodrigo C.
; Araujo, Rodrigo de O.
; Dios, Rodrigo de V.P.
; Johnsson, Rodrigo
; Feitosa, Rodrigo M.
; Hutchings, Roger W.
; Lara, Rogéria I.R.
; Rossi, Rogério V.
; Gerstmeier, Roland
; Ochoa, Ronald
; Hutchings, Rosa S.G.
; Ale-Rocha, Rosaly
; Rocha, Rosana M. da
; Tidon, Rosana
; Brito, Rosangela
; Pellens, Roseli
; Santos, Sabrina R. dos
; Santos, Sandra D. dos
; Paiva, Sandra V.
; Santos, Sandro
; Oliveira, Sarah S. de
; Costa, Sávio C.
; Gardner, Scott L.
; Leal, Sebastián A. Muñoz
; Aloquio, Sergio
; Bonecker, Sergio L.C.
; Bueno, Sergio L. de S.
; Almeida, Sérgio M. de
; Stampar, Sérgio N.
; Andena, Sérgio R.
; Posso, Sergio R.
; Lima, Sheila P.
; Gadelha, Sian de S.
; Thiengo, Silvana C.
; Cohen, Simone C.
; Brandão, Simone N.
; Rosa, Simone P.
; Ribeiro, Síria L.B.
; Letana, Sócrates D.
; Santos, Sonia B. dos
; Andrade, Sonia C.S.
; Dávila, Stephane
; Vaz, Stéphanie
; Peck, Stewart B.
; Christo, Susete W.
; Cunha, Suzan B.Z.
; Gomes, Suzete R.
; Duarte, Tácio
; Madeira-Ott, Taís
; Marques, Taísa
; Roell, Talita
; Lima, Tarcilla C. de
; Sepulveda, Tatiana A.
; Maria, Tatiana F.
; Ruschel, Tatiana P.
; Rodrigues, Thaiana
; Marinho, Thais A.
; Almeida, Thaís M. de
; Miranda, Thaís P.
; Freitas, Thales R.O.
; Pereira, Thalles P.L.
; Zacca, Thamara
; Pacheco, Thaynara L.
; Martins, Thiago F.
; Alvarenga, Thiago M.
; Carvalho, Thiago R. de
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Henry, Thomas
; Pikart, Tiago G.
; Porto, Tiago J.
; Krolow, Tiago K.
; Carvalho, Tiago P.
; Lotufo, Tito M. da C.
; Caramaschi, Ulisses
; Pinheiro, Ulisses dos S.
; Pardiñas, Ulyses F.J.
; Maia, Valéria C.
; Tavares, Valeria
; Costa, Valmir A.
; Amaral, Vanessa S. do
; Silva, Vera C.
; Wolff, Vera R. dos S.
; Slobodian, Verônica
; Silva, Vinícius B. da
; Espíndola, Vinicius C.
; Costa-Silva, Vinicius da
; Bertaco, Vinicius de A.
; Padula, Vinícius
; Ferreira, Vinicius S.
; Silva, Vitor C.P. da
; Piacentini, Vítor de Q.
; Sandoval-Gómez, Vivian E.
; Trevine, Vivian
; Sousa, Viviane R.
; Sant’Anna, Vivianne B. de
; Mathis, Wayne N.
; Souza, Wesley de O.
; Colombo, Wesley D.
; Tomaszewska, Wioletta
; Wosiacki, Wolmar B.
; Ovando, Ximena M.C.
; Leite, Yuri L.R.
.
ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
5.
Vaccination coverage, hesitancy and associated factors: a household survey of a cohort of children born in 2017 and 2018 in urban areas of state capital cities in the Brazilian Northeast coverage factors 201 20 2
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Saavedra, Ramon da Costa
; Santiago, Martha Suely Itaparica de Carvalho
; Teixeira, Maria da Glória Lima Cruz
; Antunes, Maria Bernadete de Cerqueira
; Queiroz, Rejane Christine de Sousa
; Lima, Luisa Helena de Oliveira
; Ramos Jr, Alberto Novaes
; Ferreira, Anderson Fuentes
; Maciel, Adjoane Mauricio Silva
; Barbosa, Jaqueline Caracas
; França, Ana Paula
; Domingues, Carla Magda Allan Santos
; Moraes, José Cássio de
; Silva, Adriana Ilha da
; Ramos Jr., Alberto Novaes
; França, Ana Paula
; Oliveira, Andrea de Nazaré Marvão
; Boing, Antonio Fernando
; Domingues, Carla Magda Allan Santos
; Oliveira, Consuelo Silva de
; Maciel, Ethel Leonor Noia
; Guibu, Ione Aquemi
; Mirabal, Isabelle Ribeiro Barbosa
; Barbosa, Jaqueline Caracas
; Lima, Jaqueline Costa
; Moraes, José Cássio de
; Luhm, Karin Regina
; Caetano, Karlla Antonieta Amorim
; Lima, Luisa Helena de Oliveira
; Antunes, Maria Bernadete de Cerqueira
; Teixeira, Maria da Glória Lima Cruz
; Teixeira, Maria Denise de Castro
; Borges, Maria Fernanda de Sousa Oliveira
; Queiroz, Rejane Christine de Sousa
; Gurgel, Ricardo Queiroz
; Barata, Rita Barradas
; Azevedo, Roberta Nogueira Calandrini de
; Oliveira, Sandra Maria do Valle Leone de
; Teles, Sheila Araújo
; Gama, Silvana Granado Nogueira da
; Mengue, Sotero Serrate
; Simões, Taynãna César
; Nascimento, Valdir
; Araújo, Wildo Navegantes de
.
RESUMO Objetivo Estimar a cobertura vacinal e analisar fatores sociodemográficos associados à não vacinação em crianças nascidas vivas em 2017 e 2018 nas capitais do Nordeste brasileiro. Métodos Realizou-se inquérito domiciliar com amostragem por conglomerados, entre 2020 e 2022, para estimar cobertura e hesitação vacinal. Fatores associados à não vacinação foram analisados usando-se regressão logística para calcular odds ratio (OR) e seus intervalos de confiança (IC95%). Resultados A capital com menores coberturas vacinais foi Natal, com < 75,0% para a maioria dos imunizantes; Teresina apresentou coberturas ≥ 90,0% em todos os imunizantes. Dos entrevistados, 99,1% (IC95% 98,9;99,3) acreditavam que vacinas são importantes para a saúde; 95,4% (IC95% 95,0;95,8) confiavam nos imunobiológicos distribuídos pelo governo; e 79,6% (IC95% 78,8;80,3) não tinham medo de reações adversas. Residir em estrato socioeconômico mais alto (OR ajustado: 1,34 – IC95% 1,20;1,50) foi fator associado à não vacinação. Conclusão As baixas coberturas destacam a necessidade de entender melhor as especificidades regionais e as desigualdades sociais. 201 brasileiro Realizouse Realizou se conglomerados 202 2022 usandose usando OR IC95%. IC95 IC . (IC95%) Natal 750 75 0 75,0 imunizantes 900 90 90,0 entrevistados 991 99 1 99,1 (IC95 98,999,3 989993 98,9 99,3 98 9 3 98,9;99,3 saúde 954 95 4 95,4 95,095,8 950958 95,0 95,8 8 95,0;95,8 governo 796 79 6 79,6 78,880,3 788803 78,8 80,3 78 80 78,8;80,3 adversas ajustado 134 34 1,3 1,201,50 120150 1,20 1,50 20 50 1,20;1,50 sociais IC9 7 75, 90, 99, (IC9 999 98,999, 98999 989 98, 993 98,9;99, 95, 095 95,095, 95095 950 958 95,0;95, 79, 880 78,880, 78880 788 78, 803 80, 78,8;80, 13 1, 1,201,5 12015 120 1,2 150 1,5 2 5 1,20;1,5 (IC 98,999 9899 98,9;99 09 95,095 9509 95,0;95 88 78,880 7888 78,8;80 1,201, 1201 12 15 1,20;1, 98,99 98,9;9 95,09 95,0;9 78,88 78,8;8 1,201 1,20;1 98,9; 95,0; 78,8; 1,20;
ABSTRACT Objective To estimate vaccination coverage and analyze sociodemographic factors associated with non-vaccination in children born in 2017 and 2018 in the state capitals of Northeast Brazil. Methods A household survey using cluster sampling was conducted from 2020-2022 to estimate vaccination coverage and hesitancy. Factors associated with non-vaccination were analyzed using logistic regression to calculate Odds Ratios (OR) and their Confidence Intervals (95%CI). Results Natal was the capital with the lowest vaccination coverage, below 75.0% for most immunizers. Teresina had rates equal to or greater than 90.0% for all vaccines. Among those interviewed, 99.1% (95%CI 98.9;99.3) believe that vaccines are important for health; 95.4% (95%CI 95.0;95.8) trust immunobiologicals and 79.6% (95%CI% 78.8;80.3) are not afraid of reactions. Belonging to the highest socioeconomic stratum (adjusted OR: 1.34 – 95%CI 1.20;1.50) was as a factor associated with non-vaccination. Conclusion Low coverage highlights the need for a better understanding of regional specificities and social inequalities. nonvaccination non 201 Brazil 20202022 2020 2022 2020-202 hesitancy OR (OR 95%CI. 95CI CI . 95 (95%CI) 750 75 0 75.0 immunizers 900 90 90.0 interviewed 991 99 1 99.1 98.999.3 989993 98.9 99.3 98 9 3 98.9;99.3 health 954 4 95.4 95.095.8 950958 95.0 95.8 8 95.0;95.8 796 79 6 79.6 95%CI% 78.880.3 788803 78.8 80.3 78 80 78.8;80.3 reactions adjusted 134 34 1.3 1.201.50 120150 1.20 1.50 20 50 1.20;1.50 nonvaccination. vaccination. inequalities 2020202 202 2020-20 7 75. 90. 99. 999 98.999. 98999 989 98. 993 98.9;99. 95. 095 95.095. 95095 950 958 95.0;95. 79. 880 78.880. 78880 788 78. 803 80. 78.8;80. 13 1. 1.201.5 12015 120 1.2 150 1.5 2 5 1.20;1.5 202020 2020-2 98.999 9899 98.9;99 09 95.095 9509 95.0;95 88 78.880 7888 78.8;80 1.201. 1201 12 15 1.20;1. 20202 2020- 98.99 98.9;9 95.09 95.0;9 78.88 78.8;8 1.201 1.20;1 98.9; 95.0; 78.8; 1.20;
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6.
Vaccination coverage and factors associated with incomplete polio vaccine schedule in children born in 2017-2018, in state capitals and interior region municipalities of Northeast Brazil 20172018, 20172018 2017 2018, 2018 2017-2018 2017201 201 2017-201 201720 20 2017-20 20172 2 2017-2 2017-
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Ramos Jr., Alberto Novaes
; Saavedra, Ramon da Costa
; Maciel, Adjoane Mauricio Silva
; Ferreira, Anderson Fuentes
; Silva, Taynara Lais
; Lima, Luisa Helena de Oliveira
; Domingues, Carla Magda Allan Santos
; Barbosa, Jaqueline Caracas
; Kerr, Ligia Regina Franco Sansigolo
; França, Ana Paula
; Silva, Pallysson Paulo da
; Teixeira, Maria da Gloria
; Moraes, José Cássio de
; Silva, Adriana Ilha da
; Ramos Jr., Alberto Novaes
; França, Ana Paula
; Oliveira, Andrea de Nazaré Marvão
; Boing, Antonio Fernando
; Domingues, Carla Magda Allan Santos
; Oliveira, Consuelo Silva de
; Maciel, Ethel Leonor Noia
; Guibu, Ione Aquemi
; Mirabal, Isabelle Ribeiro Barbosa
; Barbosa, Jaqueline Caracas
; Lima, Jaqueline Costa
; Moraes, José Cássio de
; Luhm, Karin Regina
; Caetano, Karlla Antonieta Amorim
; Lima, Luisa Helena de Oliveira
; Antunes, Maria Bernadete de Cerqueira
; Teixeira, Maria da Gloria
; Teixeira, Maria Denise de Castro
; Borges, Maria Fernanda de Sousa Oliveira
; Queiroz, Rejane Christine de Sousa
; Gurgel, Ricardo Queiroz
; Barata, Rita Barradas
; Azevedo, Roberta Nogueira Calandrini de
; Oliveira, Sandra Maria do Valle Leone de
; Teles, Sheila Araújo
; Gama, Silvana Granado Nogueira da
; Mengue, Sotero Serrate
; Simões, Taynãna César
; Nascimento, Valdir
; Araújo, Wildo Navegantes de
.
RESUMO Objetivo Analisar a cobertura vacinal e os fatores associados ao esquema incompleto das vacinas contra a poliomielite em coorte de nascidos vivos de 2017-2018, em capitais e municípios do interior do Nordeste brasileiro. Métodos Inquérito domiciliar em crianças com idade ≤ 24 meses, entre 2020 e 2022. Estimaram-se a cobertura vacinal, a taxa de abandono e fatores associados ao esquema de vacinação incompleto, analisados pela razão de chances (odds ratio, OR) e intervalos de confiança de 95% (IC95%). Resultados Em 12.137 crianças, a cobertura vacinal (quatro doses) foi de 80,9% (IC95% 78,4;83,1); 8,4% não eram vacinadas. Não possuir caderneta de vacinação (OR = 14,05; IC95% 8,54;23,12) e uso de serviço privado (OR = 1,46; IC95% 1,23;1,74) estiveram associados à vacinação incompleta. Taxas de abandono mais altas foram observadas na dose de reforço, principalmente no estrato alto. Conclusão Observaram-se baixas coberturas, redução no seguimento das doses e elevadas taxas de abandono para vacinas contra a poliomielite nas áreas estudadas. 20172018, 20172018 2017 2018, 2018 2017-2018 brasileiro 2 meses 202 2022 Estimaramse Estimaram se odds ratio OR 95 IC95%. IC95 IC . (IC95%) 12137 12 137 12.13 quatro 809 80 9 80,9 (IC95 78,483,1 784831 78,4 83,1 78 4 83 1 78,4;83,1) 84 8 8,4 vacinadas 14,05 1405 14 05 8,5423,12 8542312 8,54 23,12 54 23 8,54;23,12 1,46 146 46 1,231,74 123174 1,23 1,74 74 1,23;1,74 incompleta reforço alto Observaramse Observaram coberturas estudadas 2017201 201 2017-201 20 IC9 1213 13 12.1 80, (IC9 483 78,483, 78483 784 78, 831 83, 7 78,4;83,1 8, 14,0 140 0 5423 8,5423,1 854231 854 8,5 2312 23,1 5 8,54;23,1 1,4 231 1,231,7 12317 123 1,2 174 1,7 1,23;1,7 201720 2017-20 121 12. (IC 48 78,483 7848 78,4;83, 14, 542 8,5423, 85423 85 23, 8,54;23, 1, 1,231, 1231 17 1,23;1, 20172 2017-2 78,48 78,4;83 8,5423 8542 8,54;23 1,231 1,23;1 2017- 78,4;8 8,542 8,54;2 1,23; 78,4; 8,54;
ABSTRACT Objective To analyse vaccination coverage and factors associated with incomplete polio vaccination in a cohort of children born in 2017-2018, in state capitals and interior region municipalities of Northeast Brazil. Methods Household survey of children aged ≤24 months conducted between 2020 and 2022. Vaccination coverage and dropout rates were estimated, as well as factors associated with incomplete vaccination, analyzed by calculating odds ratios (OR) and 95% confidence intervals (95%CI). Results : Among 12,137 children, vaccination coverage (4 doses) was 80.9% (95%CI 78.4;83.1); 8.4% were not vaccinated. Not having a vaccination card (OR=18.06; 95%CI 10.01;32.61) and use of private services (OR=1.46; 95%CI 1.23;1.74) were associated with incomplete vaccination. Higher dropout rates were found for the booster dose, especially in the highest stratum. Conclusion Low vaccination coverage, poor dose follow-up and high dropout rates were found for polio vaccines in the areas studied. 20172018, 20172018 2017 2018, 2018 2017-2018 Brazil 24 ≤2 202 2022 estimated OR (OR 95 95%CI. 95CI CI . (95%CI) 12137 12 137 12,13 4 ( doses 809 80 9 80.9 78.483.1 784831 78.4 83.1 78 83 1 78.4;83.1) 84 8 8.4 vaccinated OR=18.06 OR1806 18 06 (OR=18.06 10.0132.61 10013261 10.01 32.61 10 01 32 61 10.01;32.61 OR=1.46 OR146 46 (OR=1.46 1.231.74 123174 1.23 1.74 23 74 1.23;1.74 stratum followup follow up studied 2017201 201 2017-201 2 ≤ 20 1213 13 12,1 80. 483 78.483. 78483 784 78. 831 83. 7 78.4;83.1 8. OR=18.0 OR180 0 (OR=18.0 0132 10.0132.6 1001326 1001 10.0 3261 32.6 3 6 10.01;32.6 OR=1.4 OR14 (OR=1.4 231 1.231.7 12317 123 1.2 174 1.7 1.23;1.7 201720 2017-20 121 12, 48 78.483 7848 78.4;83. OR=18. OR18 (OR=18. 013 10.0132. 100132 100 10. 326 32. 10.01;32. OR=1. OR1 (OR=1. 1.231. 1231 1. 17 1.23;1. 20172 2017-2 78.48 78.4;83 OR=18 (OR=18 10.0132 10013 10.01;32 OR=1 (OR=1 1.231 1.23;1 2017- 78.4;8 10.013 10.01;3 OR= (OR= 1.23; 78.4; 10.01;
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7.
Measles, mumps and rubella vaccination coverage in capitals and interior region municipalities of Northeast Brazil: a household survey in a cohort of children born in 2017 and 2018
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Maciel, Adjoane Mauricio Silva
; Ramos Jr, Alberto Novaes
; Ferreira, Anderson Fuentes
; Silva, Taynara Lais
; Domingues, Carla Magda Allan Santos
; Saavedra, Ramon da Costa
; Barbosa, Jaqueline Caracas
; França, Ana Paula
; Kerr, Ligia Regina Franco Sansigolo
; Teixeira, Maria da Gloria
; Moraes, José Cássio de
; Silva, Adriana Ilha da
; Ramos Jr., Alberto Novaes
; França, Ana Paula
; Oliveira, Andrea de Nazaré Marvão
; Boing, Antonio Fernando
; Domingues, Carla Magda Allan Santos
; Oliveira, Consuelo Silva de
; Maciel, Ethel Leonor Noia
; Guibu, Ione Aquemi
; Mirabal, Isabelle Ribeiro Barbosa
; Barbosa, Jaqueline Caracas
; Lima, Jaqueline Costa
; Moraes, José Cássio de
; Luhm, Karin Regina
; Caetano, Karlla Antonieta Amorim
; Lima, Luisa Helena de Oliveira
; Antunes, Maria Bernadete de Cerqueira
; Teixeira, Maria da Gloria
; Teixeira, Maria Denise de Castro
; Borges, Maria Fernanda de Sousa Oliveira
; Queiroz, Rejane Christine de Sousa
; Gurgel, Ricardo Queiroz
; Barata, Rita Barradas
; Azevedo, Roberta Nogueira Calandrini de
; Oliveira, Sandra Maria do Valle Leone de
; Teles, Sheila Araújo
; Gama, Silvana Granado Nogueira da
; Mengue, Sotero Serrate
; Simões, Taynãna César
; Nascimento, Valdir
; Araújo, Wildo Navegantes de
.
ABSTRACT Objective To analyze measles, mumps, and rubella vaccination coverage among children up to 24 months old and factors associated with non-vaccination in a 2017−2018 live birth cohort, in state capitals and large interior region cities in Northeast Brazil. Methods Population-based survey analyzing vaccination coverage and sociodemographic factors through logistic regression. Results For 12,137 children, vaccination coverage was 79.3% (95%CI 76.5;81.8), and the dropout rate was 10.6%. Association with non-vaccination: socioeconomic stratum A (OR-a 1.29; 95%CI 1.10;1.50), living in the interior region (OR-a 1.22; 95%CI 1.07;1.39), no access to the Bolsa Família Program (OR-a 1.19, 95%CI 1.05;1.34), family income ≤BRL 1,000 (OR-a 1.17, 95%CI 1.03;1.31), mother not working (OR-a 1.28, 95%CI 1.15;1.42), >1 child per mother (OR-a 1.12, 95%CI 1.08;1.17), and no vaccination card (OR-a 10.69, 95%CI 6.27;18.20). Conclusion Low vaccination coverage and a high dropout rate in state capitals and municipalities in the interior region of Northeast Brazil.
RESUMO Objetivo Analisar a cobertura vacinal contra sarampo, caxumba e rubéola em crianças até 24 meses de idade e os fatores associados à não vacinação em coorte de nascidos-vivos em 2017-2018, em capitais e municípios de grande porte populacional do interior do Nordeste brasileiro. Métodos Inquérito domiciliar populacional com análise de cobertura vacinal e fatores sociodemográficos por regressão logística. Resultados Em 12.137 crianças, cobertura vacinal de 79,3% (IC95% 76,5;81,8) e taxa de abandono de 10,6%. Associação à não vacinação: estrato socioeconômico A (OR-a 1,29; IC95% 1,10;1,50), residir no interior (OR-a 1,22; IC95% 1,07;1,39), não acesso ao Programa Bolsa Família (OR-a 1,19; IC95% 1,05;1,34), renda familiar ≤ R$ 1.000,00 (OR-a 1,17; IC95% 1,03;1,31), mãe sem trabalho remunerado (OR-a 1,28; IC95% 1,15;1,42), > 1 filho por mãe (OR-a 1,12; IC95% 1,08;1,17), sem caderneta de vacinação (OR-a 10,69; IC95% 6,27;18,20). Conclusão Baixa cobertura e alta taxa de abandono vacinal em capitais e municípios do interior do Nordeste.
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8.
A brazilian nationwide multicenter study on deficiency of deaminase-2 (DADA2) deaminase2 deaminase 2 deaminase- DADA2 DADA (DADA2 (DADA
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Melo, Adriana
; Carvalho, Luciana Martins de
; Ferriani, Virginia Paes Leme
; Cavalcanti, André
; Appenzeller, Simone
; Oliveira, Valéria Rossato
; Chong Neto, Herberto
; Rosário, Nelson Augusto
; Poswar, Fabiano de Oliveira
; Guimaraes, Matheus Xavier
; Kokron, Cristina Maria
; Maia, Rayana Elias
; Silva, Guilherme Diogo
; Keller, Gabriel
; Ferreira, Mauricio Domingues
; Vasconcelos, Dewton Moraes
; Toledo-Barros, Myrthes Anna Maragna
; Barros, Samar Freschi
; Rosa Neto, Nilton Salles
; Krieger, Marta Helena
; Kalil, Jorge
; Mendonça, Leonardo Oliveira
.
Abstract Introduction The deficiency of ADA2 (DADA2) is a rare autoinflammatory disease provoked by mutations in the ADA2 gene inherited in a recessive fashion. Up to this moment there is no consensus for the treatment of DADA2 and anti-TNF is the therapy of choice for chronic management whereas bone marrow transplantation is considered for refractory or severe phenotypes. Data from Brazil is scarce and this multicentric study reports 18 patients with DADA2 from Brazil. Patients and methods This is a multicentric study proposed by the Center for Rare and Immunological Disorders of the Hospital 9 de Julho - DASA, São Paulo - Brazil. Patients of any age with a confirmed diagnosis of DADA2 were eligible for this project and data on clinical, laboratory, genetics and treatment were collected. Results Eighteen patients from 10 different centers are reported here. All patients had disease onset at the pediatric age (median of 5 years) and most of them from the state of São Paulo. Vasculopathy with recurrent stroke was the most common phenotype but atypical phenotypes compatible with ALPS-like and Common Variable Immunodeficiency (CVID) was also found. All patients carried pathogenic mutations in the ADA2 gene. Acute management of vasculitis was not satisfactory with steroids in many patients and all those who used anti-TNF had favorable responses. Conclusion The low number of patients diagnosed with DADA2 in Brazil reinforces the need for disease awareness for this condition. Moreover, the absence of guidelines for diagnosis and management is also necessary (t). ADA DADA (DADA2 fashion antiTNF anti TNF 1 DASA clinical laboratory collected here median years ALPSlike ALPS like CVID (CVID found responses condition Moreover t. t . (t) (DADA (t
9.
Chronic mucocutaneous candidiasis associated with paracoccidioidomycosis in a patient with mannose receptor deficiency: First case reported in the literature
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Revista da Sociedade Brasileira de Medicina Tropical
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Abstract We describe the first report of a patient with chronic mucocutaneous candidiasis associated with disseminated and recurrent paracoccidioidomycosis. The investigation demonstrated that the patient had a mannose receptor deficiency, which would explain the patient’s susceptibility to chronic infection by Candida spp. and systemic infection by paracoccidioidomycosis. Mannose receptors are responsible for an important link between macrophages and fungal cells during phagocytosis. Deficiency of this receptor could explain the susceptibility to both fungal species, suggesting the impediment of the phagocytosis of these fungi in our patient.
https://doi.org/10.1590/0037-8682-0008-2021
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10.
Fighting HIV/AIDS in a developing country: lessons from a small cohort from the largest Brazilian city
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Casseb, Jorge
; Veiga, Ana Paula R.
; Magri, Marcello M. C.
; Monteiro, Mariana A.
; Rocha, Rosana C.
; Gascon, Maria Rita P.
; Domingues-Ferreira, Mauricio
; Polis, Thales J. B.
; Nascimento, Najara A. de Lima
; Limongelli, Isadora
; Oliveira, Ícaro S.
; Prandi, Gabriela Caetano
; Costa, Livia M. C. B. Villares
; Fonseca, Luiz A. M.
; Duarte, Alberto J. S.
.
Revista do Instituto de Medicina Tropical de São Paulo
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https://doi.org/10.1590/s1678-9946202062058
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11.
Case report of myeloperoxidase deficiency associated with disseminated paracoccidioidomycosis and peritoneal tuberculosis
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Domingues-Ferreira, Maurício
; Levy, Ariel
; Barros, Noac Chuffi
; Bertolini, Dalton Luis
; Vasconcelos, Dewton de Moraes
.
Revista da Sociedade Brasileira de Medicina Tropical
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Abstract Myeloperoxidase (MOP) is present in monocyte and neutrophil lysosomes, catalyzing hydrogen peroxide and chloride ion conversion to hypochlorous acid. MOP seems to destroy pathogens during phagocytosis by neutrophils and is considered an important defense against innumerous bacteria. We present a patient who had MOP deficiency, who presented with a subacute form of paracoccidioidomycosis and later with peritoneal tuberculosis. MOP deficiency leads to the diminished destruction of phagocytized pathogens. This case gives important evidence of an association between MOP deficiency and increased susceptibility to infection by Paracoccidioides brasiliensis and Mycobacterium tuberculosis.
https://doi.org/10.1590/0037-8682-0462-2016
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12.
Cellular immunodeficiency related to chronic dermatophytosis in a patient with Schistosoma mansoni infection: can schistosomiasis induce immunodeficiency?
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Ferreira, Maurício Domingues
; Collaniere, Anna Cristina
; Bertolini, Dalton Luís
; Barros, Noac Chuffi
; Vasconcelos, Dewton de Moraes
.
Revista da Sociedade Brasileira de Medicina Tropical
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Abstract: Here, we describe a case of hepatosplenic schistosomiasis that progressed to widespread persistent dermatophytosis. Significant T and B lymphocytopenia was confirmed. T-cell deficit is associated with increased susceptibility to fungal infections of skin and mucous membranes. The accumulation of a large amount of blood cells in the spleen could have played a crucial role in the development of lymphocytopenia in the present case. Alternatively, the schistosomiasis-induced increase in prostaglandin E2 levels could have inhibited the production of interferon-γ, a cytokine fundamental to fungal resistance. This case shows the potential of hepatosplenic schistosomiasis to impair the immune response.
https://doi.org/10.1590/0037-8682-0107-2016
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13.
Preparation and evaluation of magnetic chitosan particles modified with ethylenediamine and Fe(III) for the removal of Cr(VI) from aqueous solutions
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Toledo, Thiago V.
; Bellato, Carlos R.
; Souza, Carlos H. Ferreira de
; Domingues, Junielly T.
; Silva, Danilo de C.
; Reis, César
; Fontes, Maurício P. Ferreira
.
The adsorption of Cr(VI) in aqueous solution by magnetic particles of crosslinked chitosan-ethylenediamine-Fe(III) (MPCh-EDA-FeCL) was studied in a batch system. Fe3+ in the MPCh-EDA-FeCL permitted that adsorption of Cr(VI) occurred with maximum efficiency between pH 3 and 11. The maximum adsorption capacity at pH 7.0 was 81.04 mg g-1 at 25 ºC. The adsorption kinetic process was described by the pseudo-second-order model. Thermodynamic parameters indicated spontaneous, exothermic and chemical adsorption nature. The adsorbent was successively regenerated using a 0.1 mol L-1 NaOH solution. Results were satisfactory for treatment of wastewater from the electroplating industry.
https://doi.org/10.5935/0100-4042.20140245
3615 downloads
14.
Produção e morfologia do capim de Rhodes em seis maturidades
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Tamassia, Luis Fernando Monteiro
; Haddad, Cláudio Maluf
; Castro, Flávio Geraldo Ferreira
; Vendramini, João Maurício Bueno
; Domingues, José Luiz
.
O manejo adotado para as gramíneas forrageiras afeta sua morfologia, traduzida em porcentagem de folhas, hastes e material morto assim como sua produção de matéria seca. O objetivo do presente trabalho foi avaliar a produção e a estrutura morfológica (porcentagem de folhas, hastes, material morto) e a relação folha:haste do capim de Rhodes (Chloris gayana Kunth.) durante seu crescimento. O experimento foi desenvolvido em uma pastagem, na cidade de Piracicaba e o delineamento experimental foi de blocos completos casualizados (quatro blocos), com seis cortes (tratamentos) a cada 10 dias, sendo o primeiro 20 dias após o corte de rebaixamento. Foram observados aumento da produção de matéria seca com o decorrer do período experimental, aumentos na altura do capim do número de inflorescências da porcentagem de hastes e de material morto. A porcentagem de folhas e a relação folha:haste diminuiu com o decorrer do período experimental. O aumento no intervalo de cortes altera a morfologia do capim de Rhodes, assim como sua produção e baseando-se nisto, o melhor intervalo para cortes situa-se entre 30 e 40 de crescimento, considerando produção e porcentagem de folhas.
The grass cutting time interval affects pasture yield and morfology in terms of leaf, steam and dead material percentages. The objective of this study was to evaluate the yield, flowering time, height, structure (leaf, stem and dead material percentages) and leaf: stem ratio of a Rhodes grass (Chloris gayana Kunth.) pasture for several cutting ages. The experiment was conducted using a pasture of Piracicaba, Brazil. The experimental design consisted of completely randomized blocks, replicated four times. Treatments consisted of six cutting ages (20 to 70 days) each ten days. Increasing in yield, height, flowering, stem and dead material percentages were observed during the experimental period. Leaf percentage and leaf:stem ratio decreased during de experimental period. The cutting age affects Rhodes grass parts and yield and the optimal interval for cutting is 30 to 40 days.
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