Abstract Background The COVID-19 pandemic has triggered crises in the public health sector that have complex and multifaceted interrelationships with antimicrobial resistance. It is important to evaluate the impact of COVID-19 on microbiological profile, antibiotic and alcohol gel consumption in Intensive Care Units (ICU). Methods This is a retrospective study undertaken in an infectious disease hospital located in Bahia/Brazil during three periods: from March 2019 to February 2020; from March 2020 to February 2021; and from March 2021 to February 2022. It was evaluated the incidence density of Candida spp and of multidrug-resistant Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species (ESKAPE group) in blood, urine and tracheal secretion isolated 48 h after the patient's admission to the ICU, as well as the use of alcohol gel (in milliliters) and consumption of antibiotics in Defined Daily Dose (DDD) per 1,000 ICU patient-days in the previous year and in the first two years of COVID-19 pandemic. Results There was an increase in Candida spp. (5.81, p < 0.001, IRR = 10.47, 95 % CI 2.57‒42.62) and in carbapenem-resistant A. baumannii in clinical cultures (4.71, p < 0.001, IRR = 8.46, 95 % CI 2.07‒34.60), the latter mainly in tracheal secretions (3.18, p =0.02, IRR = 11.47, 95 % CI 1.58‒83.39). A rise in the consumption of ceftriaxone and piperacillin-tazobactam, along with an increase in the utilization of alcohol gel were observed. Conclusion The shifting microbiological profile can be attributed to both the unique characteristics of patients with COVID-19 and the adjustments made to healthcare facilities' structural and work routines. Understanding these changes is essential in addressing the accelerated impact of antimicrobial resistance during the pandemic. Therefore, conducting thorough reviews of institutional practices and routines becomes critical in mitigating the consequences of antimicrobial resistance and its implications for patient care. COVID19 COVID 19 COVID-1 ICU. . (ICU) BahiaBrazil Bahia Brazil periods 201 202 2022 multidrugresistant multidrug resistant faecium aureus pneumoniae aeruginosa ESKAPE group blood 4 s milliliters DDD (DDD 1000 1 000 1,00 patientdays days 5.81, 581 5 81 (5.81 0001 0 001 0.001 1047 10 47 10.47 9 2.57‒42.62 2574262 2 57 42 62 carbapenemresistant carbapenem 4.71, 471 71 (4.71 846 8 46 8.46 2.07‒34.60, 2073460 2.07‒34.60 , 07 34 60 2.07‒34.60) 3.18, 318 3 18 (3.18 002 02 =0.02 1147 11 11.47 1.58‒83.39. 1588339 1.58‒83.39 58 83 39 1.58‒83.39) piperacillintazobactam, piperacillintazobactam piperacillin tazobactam, tazobactam piperacillin-tazobactam observed facilities Therefore care COVID1 COVID- (ICU 20 100 00 1,0 5.81 (5.8 0.00 104 10.4 2.57‒42.6 257426 6 4.71 7 (4.7 84 8.4 207346 2.07‒34.6 3.18 31 (3.1 =0.0 114 11.4 158833 1.58‒83.3 1, 5.8 (5. 0.0 10. 2.57‒42. 25742 4.7 (4. 8. 20734 2.07‒34. 3.1 (3. =0. 11. 15883 1.58‒83. 5. (5 0. 2.57‒42 2574 4. (4 2073 2.07‒34 3. (3 =0 1588 1.58‒83 ( 2.57‒4 257 207 2.07‒3 158 1.58‒8 2.57‒ 25 2.07‒ 15 1.58‒ 2.57 2.07 1.58 2.5 2.0 1.5 2. 1.

RESUMO O déficit de conhecimento dos profissionais de saúde tem sido uma barreira para a expansão e implementação dos serviços de reabilitação pulmonar (RP), apesar dos seus benefícios comprovados para indivíduos com doença respiratória crônica (DRC). Objetivo: avaliar o preparo dos profissionais de saúde de dois municípios brasileiros para fornecer a RP no sistema público de saúde. Esse estudo, do tipo survey, foi parte de um projeto maior para implementação da RP no sistema público de saúde brasileiro. Foi utilizado um questionário autoaplicável para avaliar o conhecimento (19 questões), o treinamento (7 questões), a confiança (10 questões) e a experiência clínica (8 questões) dos fisioterapeutas (FT) e da equipe multiprofissional (EM), aplicado antes de um workshop sobre RP. No total, 44 FT e 231 EM responderam o questionário. A pontuação média de conhecimento foi de 10±3 para FT e 6±3 para EM. Poucos FT referiam ter “muita” experiência (25%) e confiança (22,7%) para realizar RP, bem como treinamento suficiente para realizar o teste de caminhada de seis minutos (27,3%). Ainda menos profissionais da EM relataram ter “muita” experiência (10%) e treinamento suficiente (4,8%) para realizar RP, assim como para planejar o programa educacional dos pacientes (10%) e ter confiança para encaminhar pacientes para a RP (6,5%). Este é o primeiro estudo a avaliar o preparo dos profissionais da rede pública de saúde no Brasil para fornecer RP. Notavelmente, tanto FT quanto EM têm baixo preparo para realizar RP nos municípios estudados, reforçando a necessidade de realização de educação continuada. , (RP) DRC. DRC . (DRC) Objetivo survey brasileiro 19 (1 questões, questões 7 ( 10 8 (FT EM, (EM) total 4 23 103 3 10± 63 6 6± muita “muita 25% 25 (25% 22,7% 227 22 (22,7% 27,3%. 273 27,3% 27 (27,3%) 10% (10% 4,8% 48 (4,8% 6,5%. 65 6,5% 5 (6,5%) Notavelmente estudados continuada (RP (DRC 1 (EM 2 (25 22,7 (22,7 27,3 (27,3% 4,8 (4,8 6,5 (6,5% (2 22, (22, 27, (27,3 4, (4, 6, (6,5 (22 (27, (4 (6, (27 (6

ABSTRACT The knowledge deficit of health professionals has been a barrier to expanding and implementing of pulmonary rehabilitation (PR) services, despite the reported benefits of PR for individuals with Chronic Respiratory Disease (CRD). This study aims to assess the preparedness of health care professionals from two Brazilian cities to perform PR in the public health system. This is survey is part of a larger project to implement PR in the Brazilian public health system. A self-administered questionnaire was used to assess the knowledge (19 questions), training (7 questions), confidence (10 questions), and clinical experience (8 questions) of physical therapists (PT) and the multiprofessional team (MT) before a PR workshop. In total, 44 PT and 231 MT answered the questionnaire. The mean total knowledge score was 10±3 for PT and 6±3 for MT. Few physical therapist reported having “a lot” of experience (25%) and confidence (22.7%) to perform PR, as well as sufficient training to conduct the six-minute walk test (27.3%).Even fewer MT reported having “a lot” of experience (10%) and sufficient training (4.8%) to perform PR, as well as to plan the educational program for patients (10%) and the confidence to refer patients to PR (6.5%). This is the first study to evaluate the preparedness of professionals from the Brazilian public health network to provide PR. Notably, both PT and MT have low preparation to perform PR in the studied cities, reinforcing the need for continuing education. (PR services CRD. CRD . (CRD) system selfadministered self administered 19 (1 questions, questions , 7 ( 10 8 (PT (MT workshop 4 23 103 3 10± 63 6 6± lot 25% 25 (25% 22.7% 227 22 (22.7% sixminute six minute 27.3%.Even 273Even Even 27.3% .Even 27 10% (10% 4.8% 48 (4.8% 6.5%. 65 6.5% 5 (6.5%) Notably education (CRD 1 2 (25 22.7 (22.7 273 27.3 4.8 (4.8 6.5 (6.5% (2 22. (22. 27. 4. (4. 6. (6.5 (22 (4 (6. (6

RESUMEN El déficit de conocimientos entre los profesionales de la salud ha sido una barrera para la expansión e implementación de los servicios de rehabilitación pulmonar (RP) a pesar de sus beneficios comprobados para las personas con enfermedad respiratoria crónica (ERC). Este estudio de encuesta forma parte de un proyecto más amplio para implantar la RP en el sistema público sanitario brasileño mediante la evaluación de la preparación de los profesionales sanitarios de dos municipios brasileños para proporcionarla. Se utilizó un cuestionario autoadministrado para evaluar los conocimientos (19 preguntas), la formación (7 preguntas), la confianza (10 preguntas) y la experiencia clínica (8 preguntas) de los fisioterapeutas (FT) y del equipo multiprofesional (EM), aplicado previamente en un taller sobre RP. La puntuación media de los conocimientos fue de 10±3 para FT y de 6±3 para EM. Menos de un tercio de los FT afirmaron que tenían “mucha” experiencia (25%) y confianza (22,7%) para realizar la RP, así como formación suficiente para realizar la prueba de la marcha de seis minutos (27,3%). Pocos profesionales del EM declararon que tenían “mucha” experiencia (10%) y formación suficiente (4,8%) para realizar la RP, así como para planificar el programa educativo (10%) y tenían confianza para derivar a pacientes para la RP (6,5%). Este es el primer estudio que evalúa la preparación de los profesionales de la red pública de salud en Brasil para proporcionar la RP, y se observa que, en los municipios donde se realizó, tanto los FT como el EM están poco preparados para llevarla a cabo, lo que refuerza la necesidad de una formación continuada. (RP ERC. ERC . (ERC) proporcionarla 19 (1 preguntas, preguntas , 7 ( 10 8 (FT EM, (EM) 103 3 10± 63 6 6± mucha “mucha 25% 25 (25% 22,7% 227 22 (22,7% 27,3%. 273 27,3% 27 (27,3%) 10% (10% 4,8% 48 4 (4,8% 6,5%. 65 6,5% 5 (6,5%) realizó cabo continuada (ERC 1 (EM 2 (25 22,7 (22,7 27,3 (27,3% 4,8 (4,8 6,5 (6,5% (2 22, (22, 27, (27,3 4, (4, 6, (6,5 (22 (27, (4 (6, (27 (6

Abstract Background There is a remarkable variability in the frequency of HLA-B27 positivity in patients with spondyloarthritis (SpA), which may be associated with different clinical presentations worldwide. However, there is a lack of data considering ethnicity and sex on the evaluation of the main clinical and prognostic outcomes in mixed-race populations. The aim of this study was to evaluate the frequency of HLA-B27 and its correlation with disease parameters in a large population of patients from the Brazilian Registry of Spondyloarthritis (RBE). Methods The RBE is a multicenter, observational, prospective cohort that enrolled patients with SpA from 46 centers representing all five geographic regions of Brazil. The inclusion criteria were as follow: (1) diagnosis of axSpA by an expert rheumatologist; (2) age ≥18 years; (3) classification according to ASAS axial. The following data were collected via a standardized protocol: demographic data, disease parameters and treatment historical. Results A total of 1096 patients were included, with 73.4% HLA-B27 positivity and a mean age of 44.4 (±13.2) years. Positive HLA-B27 was significantly associated with male sex, earlier age at disease onset and diagnosis, uveitis, and family history of SpA. Conversely, negative HLA-B27 was associated with psoriasis, higher peripheral involvement and disease activity, worse quality of life and mobility. Conclusions Our data showed that HLA-B27 positivity was associated with a classic axSpA pattern quite similar to that of Caucasian axSpA patients around the world. Furthermore, its absence was associated with peripheral manifestations and worse outcomes, suggesting a relevant phenotypic difference in a highly miscegenated population. HLAB27 HLAB HLA B27 B HLA-B2 SpA, , (SpA) worldwide However mixedrace mixed race populations RBE. . (RBE) multicenter observational 4 Brazil follow 1 (1 rheumatologist 2 (2 18 ≥1 years 3 (3 axial protocol historical 109 included 734 73 73.4 444 44 44. ±13.2 132 13 (±13.2 uveitis Conversely psoriasis activity mobility world Furthermore HLAB2 B2 HLA-B (SpA (RBE ( ≥ 10 7 73. ±13. (±13. ±13 (±13 ±1 (±1 ± (±

Generalized anxiety disorder is a highly prevalent mental disorder. Previous data indicate that more than 18 million Brazilians suffer from this condition. Traditionally, generalized anxiety disorder has been considered a mild mental health disorder, despite its links to lower life expectancy, cardiovascular disease, and suicide. The aim of this article is to combine elements of systematic and critical reviews to produce a synthesis of the best evidence about generalized anxiety disorder treatment. Systematic reviews, meta-analyses, and randomized controlled trials were included. The descriptor used in the search was “generalized anxiety disorder,” which resulted in 4,860 articles and seven other studies, of which 59 were selected. Antidepressants and benzodiazepines were indicated, as was pregabalin, and atypical antipsychotics, such as quetiapine, have been studied. Individual cognitive behavior therapy (third wave) has proven effective. There is extensive literature on many effective treatments for generalized anxiety disorder. The present review summarizes the therapeutic possibilities, emphasizing those available in Brazil. Further studies are needed to compare other available medications, assess psychotherapies and new treatments in greater depth, as well as to assess the ideal duration of therapy. Registration number: PROSPERO CRD42021288323. 1 condition Traditionally expectancy disease suicide treatment metaanalyses, metaanalyses meta analyses, analyses meta-analyses included 4860 4 860 4,86 5 selected indicated pregabalin antipsychotics quetiapine studied third wave possibilities Brazil medications depth number CRD42021288323 CRD 486 86 4,8 CRD4202128832 48 8 4, CRD420212883 CRD42021288 CRD4202128 CRD420212 CRD42021 CRD4202 CRD420 CRD42 CRD4

ABSTRACT Acute respiratory distress syndrome is a significant complication in critical care patients. COVID-19 (C19)-associated severe respiratory failure is related to it, and d-dimer rise predicts a worse outcome. To investigate the association between d-dimer and the severity of this respiratory syndrome, we conducted a study in C19 intubated patients. A retrospective, single-center observational study was conducted with 64 C19 adult intubated patients. Strata of d-dimer results between patients was evaluated using survival analysis. Survival was higher in mild respiratory distress patients. D-dimer showed poor sensitivity and specificity in predicting respiratory failure severity. Risk assessment for death showed a higher prevalence of admission d-dimer results (HR 1.335; 95% CI 0.695–2.564). Our sample confidently represented the medical profile of C19 severe patients. Sepsis development in C19 is associated with the inflammatory storm in respiratory distress syndrome. As the receiver operating curves show, the increase in d-dimer results is consistent with inflammation rather than a prognostic biomarker. As expected, severe respiratory distress patients presented higher mortality. In summary, d-dimer results are not associated with the prognosis of C19 respiratory distress syndrome patients. COVID19 COVID 19 COVID-1 C19associated Cassociated C it ddimer d dimer outcome C1 retrospective singlecenter single center 6 analysis Ddimer D HR 1.335 1335 1 335 95 0.695–2.564. 06952564 0.695–2.564 . 0 695 2 564 0.695–2.564) show biomarker expected mortality summary COVID1 COVID- 1.33 133 33 9 0695256 0.695–2.56 69 56 1.3 13 3 069525 0.695–2.5 5 1. 06952 0.695–2. 0695 0.695–2 069 0.695– 06 0.695 0.69 0.6 0.

Abstract Background SARS-CoV-2 infection has become a major international issue, not only from a medical point of view, but also social, economic and political. Most of the available information comes from the United States, Europe, and China, where the population and the socioeconomic status are very different from Latin American countries. This study evaluates the effect of regional socioeconomic characteristics on mortality due SARS-CoV-2 infection in patients with immune-mediated rheumatic diseases (IMRD) from Argentina, Mexico and Brazil. Methods Data from three national registries, SAR-COVID (Argentina), CMR-COVID (Mexico) and ReumaCoV-Brasil (Brazil), were combined. Adult IMRD patients with SARS-CoV-2 infection were recruited. National data for each province/state, including population density, number of physicians per inhabitant, income, unemployment, GINI index, Municipal Human Development Index (MHDI), stringency index, vaccination rate and most frequent viral strains per period were assessed as risk factors for mortality due to COVID-19. Results A total of 4744 patients were included, 2534 (53.4%) from SAR-COVID, 1166 (24.6%) from CMRCOVID and 1044 (22.0%) from ReumaCoV-Brasil. Mortality due to COVID-19 was 5.4%. In the multivariable analysis, higher number of physicians per 1000 inhabitants and being infected during the vaccination period of each country were associated with lower mortality. After adjustment for socioeconomic factors, there was no association with country of residence and mortality. Conclusion These findings corroborate the complex interplay between socioeconomic factors, rheumatic disease activity, and regional disparities as determinants of death due to COVID-19 in Argentina, Brazil and Mexico. Thus, this research provides valuable insights for guiding public health policies and clinical practice in the ongoing fight against the COVID-19 pandemic. SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- issue view social political States Europe China countries immunemediated immune mediated (IMRD Argentina registries SARCOVID SAR COVID , (Argentina) CMR (Mexico ReumaCoVBrasil ReumaCoV Brasil Brazil, (Brazil) combined recruited provincestate province state province/state density inhabitant income unemployment index MHDI, MHDI (MHDI) COVID19. COVID19 19. 19 474 included 253 53.4% 534 53 4 (53.4% SARCOVID, COVID, 116 24.6% 246 24 6 (24.6% 104 22.0% 220 22 0 (22.0% ReumaCoVBrasil. Brasil. COVID-1 54 5 5.4% analysis 100 activity Thus pandemic SARS-CoV (Argentina (Brazil (MHDI COVID1 1 47 25 53.4 (53.4 11 24.6 (24.6 10 22.0 (22.0 COVID- 5.4 53. (53. 24. (24. 22. (22. 5. (53 (24 (22 (5 (2 (

Objective: We investigated whether social skills are impaired in patients with obsessive-compulsive disorder (OCD), whether they changed over the course of treatment, and whether OCD severity, age of onset, and illness duration were associated with social skills deficit. Methods: A total of 41 treatment-naïve patients with OCD and 34 healthy controls were assessed using the Social Skills Inventory. Patients were reevaluated 12 weeks after standardized treatment. Group differences and the effects of treatment on OCD symptomatology over time were analyzed with independent and paired tests, respectively. OCD severity, age at illness onset, and illness duration were tested as predictors of social skills. Results: The patient group had lower overall social skill scores than controls (p < 0.001). After treatment, although OCD symptomatology (p < 0.001) improved, there was no significant difference in social skills (p = 0.673). Earlier age of symptom onset predicted lower social skill scores (p = 0.016). Conclusion: Our results suggest that, despite improved OCD symptoms, social skills did not change after treatment. Subsequent investigations with larger sample sizes and longer follow-up periods could determine whether social skills are likely to increase over time. Objective obsessivecompulsive obsessive compulsive OCD, , (OCD) severity deficit Methods 4 treatmentnaïve naïve 3 Inventory 1 tests respectively Results p 0.001. 0001 0.001 . 0 001 0.673. 0673 0.673 673 0.673) 0.016. 0016 0.016 016 0.016) Conclusion that symptoms followup follow up (OCD 000 0.00 00 067 0.67 67 0.01 01 0.0 06 0.6 6 0.

ABSTRACT Objective: MicroRNAs are small non-coding RNAs that are abundantly expressed in various biofluids, making them promising candidates for cancer biomarkers. This review aims to present current evidence on the use of miRNA as biomarkers for the non-invasive diagnosis of bladder cancer. Methods: A systematic literature review, using the Medline database, was performed in July 2022 according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. All articles were required to satisfy the risk-of-bias assessment using the Joanna Briggs Institute Critical Assessment Tools. Data were collected based on miRNA expression, sample type, expression profiles, and accuracy. Results: The initial search retrieved 437 studies, 21 of which were included in the final analysis. Most studies on miRNA expression in human fluids used urine samples for analysis. Conclusion: There is a trend to cluster the expressed miRNAs to build diagnostic panels or use them in association with other diagnostic methods to achieve reasonable accuracy. Prospero database registration: (https://www.crd.york.ac.uk/prospero/) under ID CRD42022351686. Objective noncoding non coding biofluids noninvasive invasive Methods 202 MetaAnalyses Meta Analyses guidelines riskofbias risk bias Tools type profiles accuracy Results 43 2 analysis Conclusion registration https//www.crd.york.ac.uk/prospero/ httpswwwcrdyorkacukprospero https //www.crd.york.ac.uk/prospero/ www crd york ac uk prospero (https://www.crd.york.ac.uk/prospero/ CRD42022351686 CRD 20 4 https//www.crd.york.ac.uk/prospero wwwcrdyorkacukprospero //www.crd.york.ac.uk/prospero (https://www.crd.york.ac.uk/prospero CRD4202235168 CRD420223516 CRD42022351 CRD4202235 CRD420223 CRD42022 CRD4202 CRD420 CRD42 CRD4

Resumo Examinamos a realização do aborto segundo cor ou raça das mulheres no Brasil usando dados de três edições da PNA, 2016, 2019 e 2021. Comparamos diferenciais raciais aplicando testes de diferenças de médias a dados de levantamentos separados, levantamentos combinados sem reponderação, e levantamentos combinados e reponderados. Na comparação usamos ainda modelos logísticos para a chance de realização de aborto. Os resultados indicam que há diferencial racial consistente nas três edições da PNA, com os percentuais de aborto entre as mulheres negras sendo mais elevados do que entre as mulheres brancas. Nos levantamentos combinados e reponderados, entre as mulheres negras de todas as idades a probabilidade de ter feito um aborto é de 11,03% enquanto entre as mulheres brancas é de 7,55%. Isso significa uma diferença de 3,5 pontos percentuais, que se traduz em uma probabilidade 46% maior para as negras, valores estatisticamente significantes para um intervalo de 5%. Regressões logísticas produzem resultados similares, com probabilidade média predita das mulheres negras de 12,61% e das mulheres brancas de 8,90%, também significantes. As diferenças raciais persistem estatisticamente significantes para várias combinações de edições da PNA. Porém, nos levantamentos isolados os testes de diferenças de média são estatisticamente significantes apenas em 2016. PNA 2016 201 2021 separados reponderação reponderados 1103 11 03 11,03 755 7 55 7,55% 35 3 5 3, 46 5% similares 1261 12 61 12,61 890 8 90 8,90% Porém 20 202 110 1 0 11,0 75 7,55 4 126 6 12,6 89 9 8,90 2 11, 7,5 12, 8,9 7, 8,

Abstract We examine racial differentials in abortion among women in Brazil using data from three editions of the Brazilian National Abortion Survey (PNA), 2016, 2019 and 2021. We test the difference in means in data from separate surveys, combined surveys without reweighting, and combined and reweighted surveys. We also use logistic models for the chance of having an abortion. The results indicate that there is a consistent racial differential in the three editions of PNA, with the percentage of abortions among Black women being higher than among white women. In the combined and reweighted surveys, among Black women of all ages the probability of having had an abortion is 11.03% while among white women it is 7.55%. This means a difference of 3.5 percentage points, which translates into a 46% higher probability for Black women, statistically significant values for a 5% interval. Logistic regressions produce similar results, with an average predicted probability of 12.61% for Black women and 8.90% for white women, also significant. Racial differences remain statistically significant for various combinations of PNA editions. However, in the separate surveys, the difference in means tests are only statistically significant in 2016. Black refers to the group formed by Black and Brown women (pretas and pardas). Due to the small sample size, it is not possible to say much about the differences with Asian and Indigenous women. , (PNA) 2016 201 2021 reweighting 1103 11 03 11.03 755 7 55 7.55% 35 3 5 3. points 46 interval 1261 12 61 12.61 890 8 90 8.90 However pretas pardas. pardas . pardas) size (PNA 20 202 110 1 0 11.0 75 7.55 4 126 6 12.6 89 9 8.9 2 11. 7.5 12. 8. 7.

The work aims to present Stanislavski's pedagogical method as a practical proposal for comprehensive education, through an integrative bibliographic review. The searches were carried out in the GOOGLE Academic, SciELO and CAPES databases, covering the period from 2012 to July 2022, through the analysis in full from the dialogic discourse and statistical data from scientific journals, authorial literature by Stanislavski, dissertations and selected theses. The theoretical foundation is based on the notions of aesthetic education; Stanislavski's pedagogical methodology; of comprehensive education and socio-emotional skills, neuroscientifically grounded. Based on the description of the proposed theme, an attempt was made to improve practices for genuine comprehensive education, as proposed by the BNCC. In this way, education “for life” assumes the centrality of the human being in the pedagogical process, for learning based on the paradigm of complexity in which the student is the protagonist of his/her learning in an engaged, autonomous and interactive way foreseen in the pedagogical proposal of Stanislavski.

El trabajo tiene como objetivo presentar el método pedagógico de Stanislavski como una propuesta práctica para la educación integral, a través de una revisión bibliográfica integradora. Las búsquedas se realizaron en las bases de datos GOOGLE Academic, SciELO y CAPES, abarcando el período de 2012 a julio de 2022, a través del análisis completo del discurso dialógico y datos estadísticos de revistas científicas, literatura autoral de Stanislavski, disertaciones y tesis seleccionadas. La fundamentación teórica se basa en las nociones de educación estética; la metodología pedagógica de Stanislavski; educación integral y habilidades socioemocionales, fundamentadas neurocientíficamente. Con base en la descripción del tema propuesto, se intentó mejorar las prácticas para una verdadera educación integral, tal como lo propone la BNCC. De esta forma, la educación “para la vida” asume la centralidad del ser humano en el proceso pedagógico, para un aprendizaje basado en el paradigma de la complejidad en el que el estudiante es protagonista de su aprendizaje de forma comprometida, autónoma e interactiva prevista en la propuesta pedagógica de Stanislavski.

O trabalho objetiva apresentar o método pedagógico de Stanislavski como proposta prática para a educação integral, através de uma revisão bibliográfica integrativa. As buscas foram realizadas nas bases de dados GOOGLE Acadêmico, SciELO e CAPES, compreendendo o período de 2012 a Julho de 2022, através da análise na íntegra a partir da dialógica de discurso e dados estatísticos de periódicos científicos, literatura autoral de Stanislavski, dissertações e teses selecionados. A fundamentação teórica tem como pilares as noções da educação estética; da metodologia pedagógica de Stanislavski; da educação integral e habilidades socioemocionais, embasados neurocientificamente. A partir da descrição do tema proposto, buscou-se a melhoria das práticas para uma genuína educação integral, segundo proposta da BNCC. Desta forma, a educação “para a vida” pressupõe a centralidade do ser humano no processo pedagógico, para uma aprendizagem baseada no paradigma da complexidade na qual o estudante seja protagonista da sua aprendizagem de forma engajada, autônoma e interativa prevista na proposta pedagógica de Stanislavski.

Resumo A Pesquisa Nacional de Aborto 2021 (PNA 2021) empregou questionários estruturados face a face e um questionário autoadministrado depositado em uma urna para coletar informações sobre aborto no Brasil. As entrevistas foram realizadas em uma amostra representativa de 2.000 mulheres selecionadas aleatoriamente com idades entre 18 e 39 anos e residentes em áreas urbanas. Comparamos alguns dos resultados com ondas anteriores da pesquisa, PNA 2010 e PNA 2016. O aborto está em declínio, porém segue como importante questão de saúde pública. Cerca de 10% das mulheres em 2021 disseram ter feito ao menos um aborto na vida (15% em 2010). Estimamos que aproximadamente uma em cada sete mulheres (15%) teve um aborto aos 40 anos. Houve declínio na proporção de mulheres que foram hospitalizadas para finalizar o aborto (55% em 2010; 43% em 2021; p = 0,003) e na proporção de mulheres que usaram medicamentos para o aborto (48% em 2010; 39% em 2021; p = 0,028). O aborto é um evento que ocorre no início na vida reprodutiva das mulheres: a PNA 2021 constatou que 52% tinham 19 anos ou menos quando fizeram o primeiro aborto. Taxas mais altas foram detectadas entre as entrevistadas com menor escolaridade, negras e indígenas e residentes em regiões mais pobres. 202 Brasil 2000 2 000 2.00 1 3 urbanas pesquisa 201 2016 pública 10 15% 15 (15 2010. . 2010) 4 55% 55 (55 43 0,003 0003 0 003 48% 48 (48 0,028. 0028 0,028 028 0,028) 52 escolaridade pobres 20 200 00 2.0 (1 5 (5 0,00 (4 002 0,02 02 2. ( 0,0 0,

Abstract The National Abortion Survey 2021 (PNA 2021) utilized face-to-face structured interviews and a self-administered questionnaire placed in a sealed box to collect data on abortions in Brazil. Interviews were held with a nationally representative sample of 2,000 women, randomly selected from among literate women ages 18 to 39 residing in urban areas. We compared some of the results with previous waves of the survey, PNA 2010 and PNA 2016. Findings show that abortion is in decline but remains a major public health issue. Around 10% of the women interviewed in 2021 said they had had at least one abortion in their lives (compared to 15% in 2010). We estimate that nearly one in every seven women (15%) have had an abortion by the age of 40. We identified a decline in the proportion of women who needed to be hospitalized to finalize their abortions (55% in 2010; 43% in 2021; p = 0.003) and in the proportion of women who used medication for the abortion (48% in 2010; 39% in 2021; p = 0.028). Abortion is an event that generally happens early on in women’s reproductive lives: the PNA 2021 found that 52% of women were 19 years old or younger when they had their first abortion. Higher rates were detected among respondents with lower educational levels, Black and Indigenous women, and women residing in poorer regions. 202 facetoface face selfadministered self administered Brazil 2000 2 000 2,00 1 3 areas survey 201 2016 issue 10 15 2010. . 2010) (15% 40 55% 55 (55 43 0.003 0003 0 003 48% 48 (48 0.028. 0028 0.028 028 0.028) womens s 52 levels regions 20 200 00 2,0 (15 4 5 (5 0.00 (4 002 0.02 02 2, (1 ( 0.0 0.

Abstract Objective To characterize the sociodemographic and clinical variables of people with intestinal stomas. Materials and Methods We conducted a cross-sectional study with 47 patients of a Specialized Rehabilitation Center (CER II/APAE) in the municipality of Três Lagoas, state of Mato Grosso do Sul, Midwestern Brazil, from December 2019 to June 2020. Data was analyzed using inferential descriptive statistics (Anderson-Darling, Chi-squared, and Mann-Whitney normality tests). Results Regarding the patients, 87.23% were from Três Lagoas, 51.06% were female, 40.43% were aged from 60 to 69 years, 59.57% were married, 53.19% were brown, 59.57% were catholic, 36.17% finished elementary school, 46.81% were retired, and 57.45% earned a monthly income below 1 minimum wage. Moreover, 61.70% had undergone terminal colostomy (61.70%), 61.70% had received guidance about its placing, 57.45% had it placed due to situations of urgency, 74.47% had a stoma installed due to a neoplasia, 38.30% were permanent, with 46.81% located in the inferior left quadrant (ILQ), 59.57% presented pasty effluent, 63.83% had a circular diameter, 53.19% had pouches with 2 pieces and 57.45%, with a flexible base, 87.23% had other adjunct equipment, and 95.74% had been trained in self-care. The most common complication was skin/peristomal irritant contact dermatitis (59,57%), and 65,95% of these cases were solved by teaching self-care. The type of stoma was significantly associated with the consistency of the effluent and the size of the protrusion (p> 0.05). Conclusion The results found can support strategies to implement practices to promote health, develop new public policies, to provide training in self-care, and prevent and treat complications. stomas crosssectional cross sectional 4 CER II/APAE IIAPAE II APAE Lagoas Sul Brazil 201 2020 AndersonDarling, AndersonDarling Anderson Darling, Darling (Anderson-Darling Chisquared, Chisquared Chi squared, squared Chi-squared MannWhitney Mann Whitney tests. tests . tests) 8723 87 23 87.23 5106 51 06 51.06 female 4043 40 43 40.43 6 years 5957 59 57 59.57 married 5319 53 19 53.19 brown catholic 3617 36 17 36.17 school 4681 46 81 46.81 retired 5745 45 57.45 wage Moreover 6170 61 70 61.70 61.70%, , (61.70%) placing urgency 7447 74 74.47 neoplasia 3830 38 30 38.30 permanent ILQ, ILQ (ILQ) 6383 63 83 63.83 diameter base equipment 9574 95 95.74 selfcare. selfcare self care. care self-care skinperistomal skin peristomal 59,57%, 59,57% (59,57%) 6595 65 65,95 p> p (p 0.05. 005 0.05 0 05 0.05) health policies selfcare, care, complications 20 202 872 8 87.2 510 5 51.0 404 40.4 595 59.5 531 53.1 361 3 36.1 468 46.8 574 57.4 617 7 61.7 (61.70% 744 74.4 383 38.3 (ILQ 638 63.8 957 9 95.7 59,57 (59,57% 659 65,9 00 0.0 87. 51. 40. 59. 53. 36. 46. 57. 61. (61.70 74. 38. 63. 95. 59,5 (59,57 65, 0. (61.7 59, (59,5 (61. (59, (61 (59 (6 (5 (

Abstract The National Abortion Survey 2021 (PNA 2021) utilized face-to-face structured interviews and a self-administered questionnaire placed in a sealed box to collect data on abortions in Brazil. Interviews were held with a nationally representative sample of 2,000 women, randomly selected from among literate women ages 18 to 39 residing in urban areas. We compared some of the results with previous waves of the survey, PNA 2010 and PNA 2016. Findings show that abortion is in decline but remains a major public health issue. Around 10% of the women interviewed in 2021 said they had had at least one abortion in their lives (compared to 15% in 2010). We estimate that nearly one in every seven women (15%) have had an abortion by the age of 40. We identified a decline in the proportion of women who needed to be hospitalized to finalize their abortions (55% in 2010; 43% in 2021; p = 0.003) and in the proportion of women who used medication for the abortion (48% in 2010; 39% in 2021; p = 0.028). Abortion is an event that generally happens early on in women’s reproductive lives: the PNA 2021 found that 52% of women were 19 years old or younger when they had their first abortion. Higher rates were detected among respondents with lower educational levels, Black and Indigenous women, and women residing in poorer regions.

Resumo A Pesquisa Nacional de Aborto 2021 (PNA 2021) empregou questionários estruturados face a face e um questionário autoadministrado depositado em uma urna para coletar informações sobre aborto no Brasil. As entrevistas foram realizadas em uma amostra representativa de 2.000 mulheres selecionadas aleatoriamente com idades entre 18 e 39 anos e residentes em áreas urbanas. Comparamos alguns dos resultados com ondas anteriores da pesquisa, PNA 2010 e PNA 2016. O aborto está em declínio, porém segue como importante questão de saúde pública. Cerca de 10% das mulheres em 2021 disseram ter feito ao menos um aborto na vida (15% em 2010). Estimamos que aproximadamente uma em cada sete mulheres (15%) teve um aborto aos 40 anos. Houve declínio na proporção de mulheres que foram hospitalizadas para finalizar o aborto (55% em 2010; 43% em 2021; p = 0,003) e na proporção de mulheres que usaram medicamentos para o aborto (48% em 2010; 39% em 2021; p = 0,028). O aborto é um evento que ocorre no início na vida reprodutiva das mulheres: a PNA 2021 constatou que 52% tinham 19 anos ou menos quando fizeram o primeiro aborto. Taxas mais altas foram detectadas entre as entrevistadas com menor escolaridade, negras e indígenas e residentes em regiões mais pobres.

RESUMO O objetivo deste artigo é discutir a trajetória do Sistema de Educação Superior no Brasil no que é denominado aqui de um ciclo virtuoso de 25 anos - 1990-2015, apontando principalmente ganhos e conquistas. O caminho metodológico tem o caráter exploratório, baseado tanto na técnica bibliográfica-documental como no uso de estatísticas formuladas a partir de dados secundários. 2 19902015, 19902015 1990 2015, 2015 1990-2015 conquistas exploratório bibliográficadocumental bibliográfica documental secundários 1990201 199 201 1990-201 199020 19 20 1990-20 19902 1 1990-2 1990-

ABSTRACT This article aims to discuss the trajectory the Brazilian Higher Education System followed in what we call a virtuous cycle of 25 years (1900-2015). The methodological path has an exploratory character based on statistics formulated from secondary data and bibliographical and documentary analysis. 2 19002015. 19002015 1900 2015 . (1900-2015) analysis 1900201 190 201 (1900-2015 190020 19 20 (1900-201 19002 1 (1900-20 (1900-2 (1900- (1900 (190 (19 (1 (

ABSTRACT Objective To describe the clinical, bronchoscopic, diagnostic, and therapeutic aspects between children and adults. Methods This retrospective study compared the clinical and bronchoscopic characteristics of adults and children who underwent bronchoscopy for suspected foreign body aspiration. Data on sex, outpatient or emergency origin, bronchoscopy results, characteristics of the aspirated foreign body, and complications were analyzed. Results In total, 108 patients were included in the analysis, with foreign body aspiration diagnosed in 69% of patients (30 children and 44 adults). In 91% of patients, there was a clinical history suggestive of aspiration. The mean age of the adults was 65.89 (±19.75) years, and that of the children was 2.28 (±1.78) years. Most of the children were under 3 years of age (80%), while adults were mostly 70 years of age or older (54.5%). Emergency care was more common among children than adults. The most common foreign bodies found in both age groups were organic bodies, primarily seeds. The most frequent locations of foreign bodies were the lobar bronchi in adults and the main bronchi in children. Flexible bronchoscopy is the primary method for diagnosis and treatment. Transient hypoxemia occurred particularly frequently in children (5%). Conclusion Foreign body aspiration, particularly that involving seeds, is more common in the extremes of age. A clinical history suggestive of aspiration is crucial in determining the need for bronchoscopy, which should be performed as early as possible. Flexible bronchoscopy is an effective and safe diagnostic technique. sex origin results analyzed total 10 analysis 69 30 (3 4 . adults) 91 6589 65 89 65.8 ±19.75 1975 19 75 (±19.75 228 2 28 2.2 ±1.78 178 1 78 (±1.78 80%, 80 80% , (80%) 7 54.5%. 545 54.5% 54 5 (54.5%) seeds treatment 5%. 5% (5%) possible technique 6 ( 9 658 8 65. ±19.7 197 (±19.7 22 2. ±1.7 17 (±1.7 (80% 54.5 (54.5% (5% ±19. (±19. ±1. (±1. (80 54. (54.5 (5 ±19 (±19 ±1 (±1 (8 (54. ± (± (54