Abstract: Sarcopenia (the loss of muscle mass, strength and skeletal muscle function) increases mortality and the risk of hospitalization in the older population. Although it is known that older adults with type 2 diabetes mellitus (T2DM) have a higher risk of dynapenia and sarcopenia, few studies have investigated these conditions in middle-aged populations. The objective of this study was to investigate whether T2DM, its duration, the presence of albuminuria, and glycemic control are associated with sarcopenia and its components in adults. The cross-sectional analysis was based on data from visit 2 of the Brazilian Longitudinal Study of Adult Health (2012-2014). The 2018 European Working Group on Sarcopenia in Older People criteria were used to define dynapenia, low appendicular muscle mass (LAMM), and sarcopenia (absent/probable/confirmed). The explanatory variables were: T2DM; duration of T2DM; T2DM according to the presence of albuminuria; and glycemic control (HbA1C < 7%) among people with T2DM. A total of 12,132 participants (mean age = 55.5, SD: 8.9 years) were included. The odds ratio for LAMM was greater among those with T2DM, T2DM duration from 5 to 10 years, and T2DM without albuminuria. Chances of dynapenia were higher among those with T2DM, T2DM duration > 10 years, and T2DM with and without albuminuria. The variables T2DM, T2DM ≥ 10 years, and T2DM with albuminuria increased the odds of probable sarcopenia, and T2DM duration from 5 to 10 years increased the odds of confirmed sarcopenia. The results support the importance of frequently monitoring the musculoskeletal mass and strength of individuals with T2DM to prevent sarcopenia and related outcomes.

Resumen: La sarcopenia (pérdida de masa muscular, fuerza y función muscular esquelética) aumenta la mortalidad y el riesgo de hospitalización en ancianos. Los ancianos con diabetes mellitus tipo 2 (DMT2) presentan un mayor riesgo de sufrir dinapenia y sarcopenia, pero pocos estudios han investigado poblaciones de mediana edad. El objetivo fue investigar si la DMT2, su duración, la presencia de albuminuria y el control glucémico están asociados con la sarcopenia y sus componentes en adultos. Análisis transversal basado en los datos de la visita 2 del Estudio Longitudinal de Salud del Adulto en Brasil (2012-2014). Se utilizaron los criterios del European Working Group on Sarcopenia in Older People [Grupo de Trabajo Europeo sobre Sarcopenia en Personas Mayores] del 2018 para definir dinapenia, baja masa muscular apendicular y sarcopenia (ausente/probable/confirmada). Las variables explicativas fueron las siguientes: DMT2; duración de la DMT2; DMT2 según la presencia de albuminuria; y control glucémico (HbA1c < 7%) entre personas con DMT2. Se incluyeron 12.132 participantes (edad media = 55,5, DE: 8,9 años). La razón de probabilidades de masa muscular apendicular baja fue mayor entre personas con DMT2, duración de la DMT2 entre 5 y 10 años y DMT2 sin albuminuria. Las probabilidades de dinapenia fueron mayores entre las personas con DMT2, duración de la DMT2 > 10 años y DMT2 con y sin albuminuria. Las condiciones de DMT2, DMT2 ≥ 10 años y DMT2 con albuminuria aumentaron las probabilidades de sarcopenia probable y la duración de la DMT2 entre 5 y 10 años las probabilidades de sarcopenia confirmada. Los resultados refuerzan la importancia del monitoreo frecuente de la masa y de la fuerza musculoesquelética en individuos con DMT2 para prevenir la sarcopenia y los desenlaces relacionados.

Resumo: A sarcopenia (perda de massa muscular, força e função muscular esquelética) aumenta a mortalidade e o risco de hospitalização em idosos. Idosos com diabetes mellitus tipo 2 (DMT2) apresentam risco elevado de desenvolver dinapenia e sarcopenia, mas poucos estudos investigaram populações de meia-idade. O objetivo foi investigar se DMT2, sua duração, a presença de albuminúria e o controle glicêmico estão associados à sarcopenia e seus componentes em adultos. Análise transversal baseada nos dados da segunda visita do Estudo Longitudinal de Saúde do Adulto (2012-2014). Os critérios do European Working Group on Sarcopenia in Older People [Grupo de Trabalho Europeu sobre Sarcopenia em Pessoas Idosas] de 2018 foram usados para definir dinapenia, baixa massa muscular apendicular e sarcopenia (ausente/provável/confirmada). As variáveis explicativas foram: DMT2; duração do DMT2; DMT2 de acordo com a presença de albuminúria; e controle glicêmico (HbA1c < 7%) entre pessoas com DMT2. Foram incluídos 12.132 participantes (idade média de 55,5; DP: 8,9 anos). A razão de chances para baixa massa muscular apendicular foi maior entre pessoas com DMT2, duração do DMT2 entre 5 e 10 anos e DMT2 sem albuminúria. As chances de dinapenia foram maiores entre pessoas com DMT2, duração do DMT2 > 10 anos e DMT2 com e sem albuminúria. DMT2, DMT2 ≥ 10 anos e DMT2 com albuminúria aumentaram as chances de sarcopenia provável e duração do DMT2 entre 5 e 10 anos aumentaram as chances de sarcopenia confirmada. Os resultados reforçam a importância do monitoramento frequente da massa e da força muscular em indivíduos com DMT2 para prevenir a sarcopenia e desfechos relacionados.

Resumo: A sarcopenia (perda de massa muscular, força e função muscular esquelética) aumenta a mortalidade e o risco de hospitalização em idosos. Idosos com diabetes mellitus tipo 2 (DMT2) apresentam risco elevado de desenvolver dinapenia e sarcopenia, mas poucos estudos investigaram populações de meia-idade. O objetivo foi investigar se DMT2, sua duração, a presença de albuminúria e o controle glicêmico estão associados à sarcopenia e seus componentes em adultos. Análise transversal baseada nos dados da segunda visita do Estudo Longitudinal de Saúde do Adulto (2012-2014). Os critérios do European Working Group on Sarcopenia in Older People [Grupo de Trabalho Europeu sobre Sarcopenia em Pessoas Idosas] de 2018 foram usados para definir dinapenia, baixa massa muscular apendicular e sarcopenia (ausente/provável/confirmada). As variáveis explicativas foram: DMT2; duração do DMT2; DMT2 de acordo com a presença de albuminúria; e controle glicêmico (HbA1c < 7%) entre pessoas com DMT2. Foram incluídos 12.132 participantes (idade média de 55,5; DP: 8,9 anos). A razão de chances para baixa massa muscular apendicular foi maior entre pessoas com DMT2, duração do DMT2 entre 5 e 10 anos e DMT2 sem albuminúria. As chances de dinapenia foram maiores entre pessoas com DMT2, duração do DMT2 > 10 anos e DMT2 com e sem albuminúria. DMT2, DMT2 ≥ 10 anos e DMT2 com albuminúria aumentaram as chances de sarcopenia provável e duração do DMT2 entre 5 e 10 anos aumentaram as chances de sarcopenia confirmada. Os resultados reforçam a importância do monitoramento frequente da massa e da força muscular em indivíduos com DMT2 para prevenir a sarcopenia e desfechos relacionados. Resumo perda esquelética idosos DMT (DMT2 meiaidade. meiaidade meia idade. idade meia-idade adultos 20122014. 20122014 2012 2014 . (2012-2014) Grupo Idosas 201 ausente/provável/confirmada. ausenteprovávelconfirmada ausente/provável/confirmada ausente confirmada (ausente/provável/confirmada) HbA1c HbAc HbA c 7% 7 12132 12 132 12.13 55,5 555 55 DP 89 8 9 8, anos. anos) 1 relacionados (DMT 2012201 (2012-2014 20 (ausente/provável/confirmada 1213 13 12.1 55, 201220 (2012-201 121 12. 20122 (2012-20 (2012-2 (2012- (2012 (201 (20 (2 (

Abstract: Sarcopenia (the loss of muscle mass, strength and skeletal muscle function) increases mortality and the risk of hospitalization in the older population. Although it is known that older adults with type 2 diabetes mellitus (T2DM) have a higher risk of dynapenia and sarcopenia, few studies have investigated these conditions in middle-aged populations. The objective of this study was to investigate whether T2DM, its duration, the presence of albuminuria, and glycemic control are associated with sarcopenia and its components in adults. The cross-sectional analysis was based on data from visit 2 of the Brazilian Longitudinal Study of Adult Health (2012-2014). The 2018 European Working Group on Sarcopenia in Older People criteria were used to define dynapenia, low appendicular muscle mass (LAMM), and sarcopenia (absent/probable/confirmed). The explanatory variables were: T2DM; duration of T2DM; T2DM according to the presence of albuminuria; and glycemic control (HbA1C < 7%) among people with T2DM. A total of 12,132 participants (mean age = 55.5, SD: 8.9 years) were included. The odds ratio for LAMM was greater among those with T2DM, T2DM duration from 5 to 10 years, and T2DM without albuminuria. Chances of dynapenia were higher among those with T2DM, T2DM duration > 10 years, and T2DM with and without albuminuria. The variables T2DM, T2DM ≥ 10 years, and T2DM with albuminuria increased the odds of probable sarcopenia, and T2DM duration from 5 to 10 years increased the odds of confirmed sarcopenia. The results support the importance of frequently monitoring the musculoskeletal mass and strength of individuals with T2DM to prevent sarcopenia and related outcomes. Abstract function population TDM T DM (T2DM middleaged middle aged populations crosssectional cross sectional 20122014. 20122014 2012 2014 . (2012-2014) 201 LAMM, , (LAMM) absent/probable/confirmed. absentprobableconfirmed absent/probable/confirmed absent (absent/probable/confirmed) HbA1C HbAC HbA C 7% 7 12132 12 132 12,13 mean 555 55 55.5 SD 89 8 9 8. included 1 outcomes 2012201 (2012-2014 20 (LAMM (absent/probable/confirmed 1213 13 12,1 55. 201220 (2012-201 121 12, 20122 (2012-20 (2012-2 (2012- (2012 (201 (20 (2 (

Resumen: La sarcopenia (pérdida de masa muscular, fuerza y función muscular esquelética) aumenta la mortalidad y el riesgo de hospitalización en ancianos. Los ancianos con diabetes mellitus tipo 2 (DMT2) presentan un mayor riesgo de sufrir dinapenia y sarcopenia, pero pocos estudios han investigado poblaciones de mediana edad. El objetivo fue investigar si la DMT2, su duración, la presencia de albuminuria y el control glucémico están asociados con la sarcopenia y sus componentes en adultos. Análisis transversal basado en los datos de la visita 2 del Estudio Longitudinal de Salud del Adulto en Brasil (2012-2014). Se utilizaron los criterios del European Working Group on Sarcopenia in Older People [Grupo de Trabajo Europeo sobre Sarcopenia en Personas Mayores] del 2018 para definir dinapenia, baja masa muscular apendicular y sarcopenia (ausente/probable/confirmada). Las variables explicativas fueron las siguientes: DMT2; duración de la DMT2; DMT2 según la presencia de albuminuria; y control glucémico (HbA1c < 7%) entre personas con DMT2. Se incluyeron 12.132 participantes (edad media = 55,5, DE: 8,9 años). La razón de probabilidades de masa muscular apendicular baja fue mayor entre personas con DMT2, duración de la DMT2 entre 5 y 10 años y DMT2 sin albuminuria. Las probabilidades de dinapenia fueron mayores entre las personas con DMT2, duración de la DMT2 > 10 años y DMT2 con y sin albuminuria. Las condiciones de DMT2, DMT2 ≥ 10 años y DMT2 con albuminuria aumentaron las probabilidades de sarcopenia probable y la duración de la DMT2 entre 5 y 10 años las probabilidades de sarcopenia confirmada. Los resultados refuerzan la importancia del monitoreo frecuente de la masa y de la fuerza musculoesquelética en individuos con DMT2 para prevenir la sarcopenia y los desenlaces relacionados. Resumen pérdida esquelética DMT (DMT2 edad adultos 20122014. 20122014 2012 2014 . (2012-2014) Grupo Mayores 201 ausente/probable/confirmada. ausenteprobableconfirmada ausente/probable/confirmada ausente confirmada (ausente/probable/confirmada) siguientes HbA1c HbAc HbA c 7% 7 12132 12 132 12.13 555 55 55,5 DE 89 8 9 8, años. años) 1 relacionados (DMT 2012201 (2012-2014 20 (ausente/probable/confirmada 1213 13 12.1 55, 201220 (2012-201 121 12. 20122 (2012-20 (2012-2 (2012- (2012 (201 (20 (2 (

RESUMO Objetivo: verificar a associação do tipo e grau de perda auditiva com os fatores demográficos e as categorias da Classificação Internacional de Funcionalidade, Incapacidade e Saúde relativas a “Estruturas e Funções do Corpo” e “Atividades e Participação”. Métodos: trata-se de estudo observacional, analítico e transversal, com amostra não probabilística, desenvolvido com dados secundários, embasados na Classificação Internacional de Funcionalidade, Incapacidade e Saúde, obtidos no prontuário de usuários submetidos à avaliação para reabilitação auditiva, em um Centro Especializado em Reabilitação. Foram realizadas análises descritiva e bivariada. Para as análises de associação, foi utilizado o teste Qui-quadrado de Pearson com o nível de significância de 5%. Resultados: foram analisados 122 prontuários, que revelaram predominância de mulheres, perda auditiva do tipo neurossensorial de grau moderadamente severo e história progressiva. O tipo de perda auditiva apresentou associação com três categorias de Estruturas e Funções do corpo e três categorias de Atividades e Participação. Em relação ao grau da perda auditiva, dez categorias foram associadas com as Estruturas e Funções do corpo e seis categorias com as Atividades e Participação. Conclusão: o tipo e grau da perda auditiva associam-se com as Estruturas e Funções do corpo e com as Atividades e Participação, com maior prejuízo na comunicação. Objetivo Funcionalidade Corpo Participação . Participação” Métodos tratase trata se observacional transversal probabilística secundários Reabilitação bivariada Quiquadrado Qui quadrado 5 5% Resultados 12 prontuários mulheres progressiva Conclusão associamse associam comunicação 1

ABSTRACT Purpose: to verify the association between types and degrees of hearing loss and demographic factors and categories of the International Classification of Functioning, Disability, and Health, related to “Body Structures and Functions” and “Activities and Participation.” Methods: a cross-sectional, analytical, observational study with a nonprobabilistic sample, developed with secondary data, according to the International Classification of Functioning, Disability, and Health, obtained from the medical records of patients assessed for hearing rehabilitation at a specialized rehabilitation center. Descriptive and bivariate analyses were performed. Association analyses used Pearson’s chi-square test, with the significance level set at 5%. Results: the study analyzed 122 medical records, which revealed a predominance of women, a sensorineural hearing loss of a moderately severe degree and progressive history. The type of hearing loss was associated with three categories of Body Structures and Functions and three categories of Activities and Participation. The degrees of hearing loss were associated with 10 categories of Body Structures and Functions and six categories of Activities and Participation. Conclusion: types and degrees of hearing loss are associated with Body Structures and Functions and Activities and Participation, further impairing communication. Purpose Functioning Disability Health Participation Methods crosssectional, crosssectional cross sectional, sectional cross-sectional analytical sample data center performed Pearsons Pearson s chisquare chi square test 5 5% Results 12 women history 1 Conclusion communication

Abstract Background SARS-CoV-2 infection has become a major international issue, not only from a medical point of view, but also social, economic and political. Most of the available information comes from the United States, Europe, and China, where the population and the socioeconomic status are very different from Latin American countries. This study evaluates the effect of regional socioeconomic characteristics on mortality due SARS-CoV-2 infection in patients with immune-mediated rheumatic diseases (IMRD) from Argentina, Mexico and Brazil. Methods Data from three national registries, SAR-COVID (Argentina), CMR-COVID (Mexico) and ReumaCoV-Brasil (Brazil), were combined. Adult IMRD patients with SARS-CoV-2 infection were recruited. National data for each province/state, including population density, number of physicians per inhabitant, income, unemployment, GINI index, Municipal Human Development Index (MHDI), stringency index, vaccination rate and most frequent viral strains per period were assessed as risk factors for mortality due to COVID-19. Results A total of 4744 patients were included, 2534 (53.4%) from SAR-COVID, 1166 (24.6%) from CMRCOVID and 1044 (22.0%) from ReumaCoV-Brasil. Mortality due to COVID-19 was 5.4%. In the multivariable analysis, higher number of physicians per 1000 inhabitants and being infected during the vaccination period of each country were associated with lower mortality. After adjustment for socioeconomic factors, there was no association with country of residence and mortality. Conclusion These findings corroborate the complex interplay between socioeconomic factors, rheumatic disease activity, and regional disparities as determinants of death due to COVID-19 in Argentina, Brazil and Mexico. Thus, this research provides valuable insights for guiding public health policies and clinical practice in the ongoing fight against the COVID-19 pandemic. SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- issue view social political States Europe China countries immunemediated immune mediated (IMRD Argentina registries SARCOVID SAR COVID , (Argentina) CMR (Mexico ReumaCoVBrasil ReumaCoV Brasil Brazil, (Brazil) combined recruited provincestate province state province/state density inhabitant income unemployment index MHDI, MHDI (MHDI) COVID19. COVID19 19. 19 474 included 253 53.4% 534 53 4 (53.4% SARCOVID, COVID, 116 24.6% 246 24 6 (24.6% 104 22.0% 220 22 0 (22.0% ReumaCoVBrasil. Brasil. COVID-1 54 5 5.4% analysis 100 activity Thus pandemic SARS-CoV (Argentina (Brazil (MHDI COVID1 1 47 25 53.4 (53.4 11 24.6 (24.6 10 22.0 (22.0 COVID- 5.4 53. (53. 24. (24. 22. (22. 5. (53 (24 (22 (5 (2 (

Objective: The risk of suicide is higher among health care workers than other workers. This study investigated the association between social support and suicidal ideation and behavior during the COVID-19 pandemic among Brazilian health care workers. Methods: This study used data from 10,885 respondents to the first (time point 1 – between May and June of 2020) and second (time point 2 – between December 2020 and February 2021) cross-sectional online surveys about mental health and quality of life among Brazilian health care workers during the COVID-19 pandemic. The relationship between social support as the independent variable (time point 1) and suicidal ideation and behavior as the outcomes (time point 2) was investigated through logistic regression analysis. Results: Greater social support was associated with a significantly lower risk of reporting suicidal ideation and behavior in the month prior to follow-up assessment (adjusted OR: 0.71, 95%CI 0.66-0.76 and adjusted OR 0.61, 95%CI 0.54-0.68, respectively). These associations were independent of sex, age, feelings of loneliness, and self-reported psychiatric disorders. Conclusion: Social support is associated with a lower risk of suicidality among health care workers, and its protective role appears more closely related to suicidal behavior. Objective COVID19 COVID 19 COVID-1 Methods 10885 10 885 10,88 time 202 2021 crosssectional cross sectional analysis Results followup follow up 071 0 71 0.71 95CI CI 95 0.660.76 066076 0.66 0.76 66 76 0.66-0.7 061 61 0.61 0.540.68, 054068 0.54 0.68, 54 68 0.54-0.68 respectively. respectively . respectively) sex age loneliness selfreported self reported disorders Conclusion COVID1 COVID- 1088 88 10,8 20 07 7 0.7 9 660 0.660.7 06607 066 0.6 076 6 0.66-0. 06 540 0.540.68 05406 054 0.5 068 0.68 5 0.54-0.6 108 8 10, 0. 0.660. 0660 0.66-0 0.540.6 0540 05 0.54-0. 0.660 0.66- 0.540. 0.54-0 0.540 0.54-

This study aimed to develop and evaluate chitosan (CS) and chitosan with N-Acetyl-D-glucosamine (CS/GlcNAc) sutures, comparing them to commercial Catgut sutures. Medium molecular weight chitosan was processed into sutures using the wet-spinning method, both with and without the addition of GlcNAc. The mechanical properties, surface morphology, biocompatibility, biodegradability and in vivo response of the sutures were evaluated. Scanning electron microscopy (SEM) and enzymatic degradation tests in phosphate-buffered saline (PBS) with lysozyme were conducted. Cytotoxicity was assessed using an agar diffusion assay on L929 cells. In vivo studies involved suturing rat skin, with monitoring at 5, 15 and 25 days post-surgery. Both macroscopic and microscopic analyses were performed to evaluate wound healing, tissue response, and complications. The chitosan-based sutures exhibited tensile strength within the standards for surgical sutures under dry and hydrated conditions. Particularly, the CS/GlcNAc sutures exhibited superior biodegradability, and biocompatibility compared to Catgut sutures. These sutures promoted tissue healing, reduced adverse tissue reactions and infections, and displayed non-toxic to L929 cells and favorable microbiological characteristics. Thus, CS and CS/GlcNAc sutures present promising alternatives to traditional Catgut sutures, contributing valuable advancements to the field of biodegradable surgical materials. (CS NAcetylDglucosamine N Acetyl D glucosamine CSGlcNAc GlcNAc (CS/GlcNAc wetspinning wet spinning method properties morphology evaluated SEM (SEM phosphatebuffered phosphate buffered PBS (PBS conducted L L92 skin 5 1 2 postsurgery. postsurgery post surgery. surgery post-surgery healing complications chitosanbased based conditions Particularly infections nontoxic non toxic characteristics Thus materials L9

Resumo Examinamos a realização do aborto segundo cor ou raça das mulheres no Brasil usando dados de três edições da PNA, 2016, 2019 e 2021. Comparamos diferenciais raciais aplicando testes de diferenças de médias a dados de levantamentos separados, levantamentos combinados sem reponderação, e levantamentos combinados e reponderados. Na comparação usamos ainda modelos logísticos para a chance de realização de aborto. Os resultados indicam que há diferencial racial consistente nas três edições da PNA, com os percentuais de aborto entre as mulheres negras sendo mais elevados do que entre as mulheres brancas. Nos levantamentos combinados e reponderados, entre as mulheres negras de todas as idades a probabilidade de ter feito um aborto é de 11,03% enquanto entre as mulheres brancas é de 7,55%. Isso significa uma diferença de 3,5 pontos percentuais, que se traduz em uma probabilidade 46% maior para as negras, valores estatisticamente significantes para um intervalo de 5%. Regressões logísticas produzem resultados similares, com probabilidade média predita das mulheres negras de 12,61% e das mulheres brancas de 8,90%, também significantes. As diferenças raciais persistem estatisticamente significantes para várias combinações de edições da PNA. Porém, nos levantamentos isolados os testes de diferenças de média são estatisticamente significantes apenas em 2016. PNA 2016 201 2021 separados reponderação reponderados 1103 11 03 11,03 755 7 55 7,55% 35 3 5 3, 46 5% similares 1261 12 61 12,61 890 8 90 8,90% Porém 20 202 110 1 0 11,0 75 7,55 4 126 6 12,6 89 9 8,90 2 11, 7,5 12, 8,9 7, 8,

Abstract We examine racial differentials in abortion among women in Brazil using data from three editions of the Brazilian National Abortion Survey (PNA), 2016, 2019 and 2021. We test the difference in means in data from separate surveys, combined surveys without reweighting, and combined and reweighted surveys. We also use logistic models for the chance of having an abortion. The results indicate that there is a consistent racial differential in the three editions of PNA, with the percentage of abortions among Black women being higher than among white women. In the combined and reweighted surveys, among Black women of all ages the probability of having had an abortion is 11.03% while among white women it is 7.55%. This means a difference of 3.5 percentage points, which translates into a 46% higher probability for Black women, statistically significant values for a 5% interval. Logistic regressions produce similar results, with an average predicted probability of 12.61% for Black women and 8.90% for white women, also significant. Racial differences remain statistically significant for various combinations of PNA editions. However, in the separate surveys, the difference in means tests are only statistically significant in 2016. Black refers to the group formed by Black and Brown women (pretas and pardas). Due to the small sample size, it is not possible to say much about the differences with Asian and Indigenous women. , (PNA) 2016 201 2021 reweighting 1103 11 03 11.03 755 7 55 7.55% 35 3 5 3. points 46 interval 1261 12 61 12.61 890 8 90 8.90 However pretas pardas. pardas . pardas) size (PNA 20 202 110 1 0 11.0 75 7.55 4 126 6 12.6 89 9 8.9 2 11. 7.5 12. 8. 7.

Resumo A Pesquisa Nacional de Aborto 2021 (PNA 2021) empregou questionários estruturados face a face e um questionário autoadministrado depositado em uma urna para coletar informações sobre aborto no Brasil. As entrevistas foram realizadas em uma amostra representativa de 2.000 mulheres selecionadas aleatoriamente com idades entre 18 e 39 anos e residentes em áreas urbanas. Comparamos alguns dos resultados com ondas anteriores da pesquisa, PNA 2010 e PNA 2016. O aborto está em declínio, porém segue como importante questão de saúde pública. Cerca de 10% das mulheres em 2021 disseram ter feito ao menos um aborto na vida (15% em 2010). Estimamos que aproximadamente uma em cada sete mulheres (15%) teve um aborto aos 40 anos. Houve declínio na proporção de mulheres que foram hospitalizadas para finalizar o aborto (55% em 2010; 43% em 2021; p = 0,003) e na proporção de mulheres que usaram medicamentos para o aborto (48% em 2010; 39% em 2021; p = 0,028). O aborto é um evento que ocorre no início na vida reprodutiva das mulheres: a PNA 2021 constatou que 52% tinham 19 anos ou menos quando fizeram o primeiro aborto. Taxas mais altas foram detectadas entre as entrevistadas com menor escolaridade, negras e indígenas e residentes em regiões mais pobres. 202 Brasil 2000 2 000 2.00 1 3 urbanas pesquisa 201 2016 pública 10 15% 15 (15 2010. . 2010) 4 55% 55 (55 43 0,003 0003 0 003 48% 48 (48 0,028. 0028 0,028 028 0,028) 52 escolaridade pobres 20 200 00 2.0 (1 5 (5 0,00 (4 002 0,02 02 2. ( 0,0 0,

Abstract The National Abortion Survey 2021 (PNA 2021) utilized face-to-face structured interviews and a self-administered questionnaire placed in a sealed box to collect data on abortions in Brazil. Interviews were held with a nationally representative sample of 2,000 women, randomly selected from among literate women ages 18 to 39 residing in urban areas. We compared some of the results with previous waves of the survey, PNA 2010 and PNA 2016. Findings show that abortion is in decline but remains a major public health issue. Around 10% of the women interviewed in 2021 said they had had at least one abortion in their lives (compared to 15% in 2010). We estimate that nearly one in every seven women (15%) have had an abortion by the age of 40. We identified a decline in the proportion of women who needed to be hospitalized to finalize their abortions (55% in 2010; 43% in 2021; p = 0.003) and in the proportion of women who used medication for the abortion (48% in 2010; 39% in 2021; p = 0.028). Abortion is an event that generally happens early on in women’s reproductive lives: the PNA 2021 found that 52% of women were 19 years old or younger when they had their first abortion. Higher rates were detected among respondents with lower educational levels, Black and Indigenous women, and women residing in poorer regions. 202 facetoface face selfadministered self administered Brazil 2000 2 000 2,00 1 3 areas survey 201 2016 issue 10 15 2010. . 2010) (15% 40 55% 55 (55 43 0.003 0003 0 003 48% 48 (48 0.028. 0028 0.028 028 0.028) womens s 52 levels regions 20 200 00 2,0 (15 4 5 (5 0.00 (4 002 0.02 02 2, (1 ( 0.0 0.

Abstract The National Abortion Survey 2021 (PNA 2021) utilized face-to-face structured interviews and a self-administered questionnaire placed in a sealed box to collect data on abortions in Brazil. Interviews were held with a nationally representative sample of 2,000 women, randomly selected from among literate women ages 18 to 39 residing in urban areas. We compared some of the results with previous waves of the survey, PNA 2010 and PNA 2016. Findings show that abortion is in decline but remains a major public health issue. Around 10% of the women interviewed in 2021 said they had had at least one abortion in their lives (compared to 15% in 2010). We estimate that nearly one in every seven women (15%) have had an abortion by the age of 40. We identified a decline in the proportion of women who needed to be hospitalized to finalize their abortions (55% in 2010; 43% in 2021; p = 0.003) and in the proportion of women who used medication for the abortion (48% in 2010; 39% in 2021; p = 0.028). Abortion is an event that generally happens early on in women’s reproductive lives: the PNA 2021 found that 52% of women were 19 years old or younger when they had their first abortion. Higher rates were detected among respondents with lower educational levels, Black and Indigenous women, and women residing in poorer regions.

Resumo A Pesquisa Nacional de Aborto 2021 (PNA 2021) empregou questionários estruturados face a face e um questionário autoadministrado depositado em uma urna para coletar informações sobre aborto no Brasil. As entrevistas foram realizadas em uma amostra representativa de 2.000 mulheres selecionadas aleatoriamente com idades entre 18 e 39 anos e residentes em áreas urbanas. Comparamos alguns dos resultados com ondas anteriores da pesquisa, PNA 2010 e PNA 2016. O aborto está em declínio, porém segue como importante questão de saúde pública. Cerca de 10% das mulheres em 2021 disseram ter feito ao menos um aborto na vida (15% em 2010). Estimamos que aproximadamente uma em cada sete mulheres (15%) teve um aborto aos 40 anos. Houve declínio na proporção de mulheres que foram hospitalizadas para finalizar o aborto (55% em 2010; 43% em 2021; p = 0,003) e na proporção de mulheres que usaram medicamentos para o aborto (48% em 2010; 39% em 2021; p = 0,028). O aborto é um evento que ocorre no início na vida reprodutiva das mulheres: a PNA 2021 constatou que 52% tinham 19 anos ou menos quando fizeram o primeiro aborto. Taxas mais altas foram detectadas entre as entrevistadas com menor escolaridade, negras e indígenas e residentes em regiões mais pobres.

Abstract The Parauapebas Formation and Igarapé Cigarra Formation constitute two Neoarchean extrusive units inserted in the metavolcanosedimentary sequence (~2.76 Ga) of the Grão Pará Group, Itacaiúnas Supergroup, being represented by basaltic seeps underlain and overlain by jaspillites, rhyolites, volcanoclastic rocks, and gabbro dikes/sills, thus being inserted in the Serra Sul district in the Mineral Province of Carajás, Pará. This study aimed to understand the igneous processes involved in the genesis of these basalts from both geological formations, supported by field, petrographic, and geochemical data. Inserted in the metavolcanosedimentary sequence of the Grão Pará Group (Carajás Domain), the basalts and basalt andesites, the most abundant types of the Parauapebas and Igarapé Cigarra Formations, occur as successions of massive and amygdaloidal lava flows. The study of core samples from nine stratigraphic holes that intersected basaltic rocks of the two geological formations in body S11D (Serra Sul) showed that these rocks reach thick layers with different characteristics, ranging from aphanitic to phaneritic. The basalts are dark green, aphanitic, phaneritic, thin to medium, and hypocrystalline. They show preserved igneous texture being commonly seriated as inequigranular, intersertal, ophitic, subophytic, intergranular, branching, and swallow tail. Its essential primary constituents are plagioclase, orthopyroxene, and clinopyroxene, and its accessory constituents are titanite and apatite. Chlorite, epidote, quartz, and calcite occur as secondary phases and are interpreted as the products of ocean-bottom hydrothermal alteration and/or incipient metamorphism. In general, the studied volcanic rocks stand out for SiO2 content between 47.00 and 56.04%, high alkali contents (4.70–7.50%), K2O contents between 0.40 and 3.97%, TiO2 (< 1.0%), and MgO between 4.90 and 8.16%. In the classification diagrams, the samples are situated in the fields of basalts, basalt andesites, trachyandesite, and trachybasalt basalts, in the transition of the toleitic and calc-alkaline series. The basalts of the Parauapebas and Igarapé Cigarra Formations were probably formed in an intraplate continental environment influenced by subduction zones. Therefore, the Grão-Pará Basin was probably formed in a convergent regime related to a subduction-type environment. The geochemical data indicate that the studied rocks of the Parauapebas Formation and the Igarapé Cigarra Formation correspond to basalts of calc-alkaline affinity. Two facies were identified in the Parauapebas Formation, namely, the Amendoim and Violão facies. In the Igarapé Cigarra Formation as well, the following facies were identified: Jacaré and Três Marias. Based on the geochemical interpretation, it is assumed that the rocks studied are arc-like continental basalts, which are formed in a subduction environment with influence from a possible asthenospheric source and modified by crustal contamination. ~2.76 276 2 76 (~2.7 Ga Supergroup jaspillites rhyolites dikessills dikes sills dikes/sills Carajás field petrographic Domain, Domain , Domain) andesites flows SD S D characteristics phaneritic green medium hypocrystalline inequigranular intersertal ophitic subophytic intergranular branching tail plagioclase orthopyroxene clinopyroxene apatite Chlorite epidote quartz oceanbottom ocean bottom andor or metamorphism general SiO 4700 47 00 47.0 5604 56 04 56.04% 4.70–7.50%, 470750 4.70–7.50% 4 70 7 50 (4.70–7.50%) KO K O 040 0 40 0.4 397 3 97 3.97% TiO < ( 1.0%, 10 1.0% 1 1.0%) 490 90 4.9 816 8 16 8.16% diagrams trachyandesite calcalkaline calc alkaline series zones Therefore GrãoPará subductiontype type affinity namely well Marias interpretation arclike arc like contamination ~2.7 27 (~2. 470 47. 560 5 56.04 47075 4.70–7.50 (4.70–7.50% 0. 39 9 3.97 1.0 49 4. 81 8.16 ~2. (~2 56.0 4707 4.70–7.5 (4.70–7.50 3.9 1. 8.1 ~2 (~ 56. 4.70–7. (4.70–7.5 3. 8. ~ 4.70–7 (4.70–7. 4.70– (4.70–7 4.70 (4.70– 4.7 (4.70 (4.7 (4. (4

Abstract Objective: To translate and validate the version for children and adolescents of the UPPS-P scale into Brazilian Portuguese. Method: After a five-step translation process, the final draft was submitted to a panel of 12 different specialties experts. Subsequently, the application of the scale was applied concomitantly with the "Swanson, Nolan, and Pelham Scale - Version IV" (SNAP-IV) and the "Child and Adolescent Behavior Inventory" (CABI) scale to analyze the correlation between them. Content Validity Index (CVI) and reliability were estimated by calculating internal consistency and analyzing its test-retest stability. Results: The items whose CVI was lower than 80% underwent a detailed analysis to verify the reason for the bad evaluation. Five items (3, 7, 11, 22 and 35) scored below 80% and were reassessed. There was high internal consistency in all parameters: Lack of premeditation (McDonald's omega = 0.806; Cronbach's alpha = 0.801), Negative Urgency (McDonald's omega = 0.838; Cronbach's alpha = 0.836), Sensation seeking (McDonald's omega = 0.826; Cronbach's alpha = 0.810), Lack of Perseverance (McDonald's omega = 0.800; Cronbach's alpha = 0.799) and Positive Urgency (McDonald's omega = 0.936; Cronbach's alpha = 0.934). A strong correlation was observed between UPPS-P features and impulsivity in behavioral assessments. Conclusions: The Brazilian Portuguese version of the UPPS-P scale is a good instrument to assess impulsivity in children and adolescents. Objective UPPSP UPPS P Method fivestep five step process 1 experts Subsequently Swanson, Swanson "Swanson Nolan IV SNAPIV SNAP (SNAP-IV Child Inventory CABI (CABI them (CVI testretest test retest stability Results 80 evaluation 3, 3 (3 7 11 2 35 reassessed parameters McDonalds McDonald s 0.806 0806 0 806 Cronbachs Cronbach 0.801, 0801 0.801 , 801 0.801) 0.838 0838 838 0.836, 0836 0.836 836 0.836) 0.826 0826 826 0.810, 0810 0.810 810 0.810) 0.800 0800 800 0.799 0799 799 0.936 0936 936 0.934. 0934 0.934 . 934 0.934) assessments Conclusions 8 ( 0.80 080 0.83 083 83 0.82 082 82 081 0.81 81 0.79 079 79 0.93 093 93 0.8 08 0.7 07 0.9 09 9 0.

Resumo Estudos que exploram o uso de lipídios e seus efeitos na nutrição animal têm se tornado cada vez mais abundantes, produzindo uma grande quantidade de informações. A revisão foi realizada de forma paritária por meio de uma pesquisa de artigos nas bases bibliográficas: Web of Science e Periódicos Capes, utilizando termos de busca associados ou não, no plural ou no singular, em inglês e português, tais como: "lipídios" E "coelhos" E "nutrição". Após analisar os arquivos nas duas bases científicas, determinados arquivos foram excluídos porque não se adequavam ao tema ou não atendiam aos critérios de inclusão, além de artigos repetidos. Um teste de relevância foi realizado para a seleção dos artigos, nos quais eles deveriam tratar do assunto: artigos que relatam o uso de lipídios na nutrição de animais não-ruminantes; artigos disponibilizados na forma completa; artigos que possuíam pelo menos uma das palavras-chave; artigos nos quais o assunto principal está relacionado a lipídios. Os artigos foram selecionados e tabulados em uma planilha do Excel® com informações relevantes para exploração na revisão. O uso de óleos e gorduras é um ponto favorável na nutrição de animais não-ruminantes, apresentando benefícios no enriquecimento de produtos finais, tais como: fornecer níveis mais altos de ômega-3 e ômega-6, e assim obter produtos de carne com menores teores de gordura saturada e maiores teores de gordura insaturada, promovendo benefícios para a saúde humana por meio do consumo, redução dos custos alimentares, melhoria na palatabilidade e aparência dos alimentos. Essas são estratégias nutricionais usadas nas estações quentes do ano devido ao baixo incremento calórico produzido. abundantes bibliográficas Capes singular português como "lipídios coelhos "coelhos nutrição. . "nutrição" científicas inclusão repetidos nãoruminantes ruminantes não-ruminantes completa palavraschave palavras chave palavras-chave Excel nãoruminantes, ruminantes, finais ômega3 ômega 3 ômega- ômega6, ômega6 6, 6 ômega-6 insaturada consumo alimentares alimentos produzido "nutrição

Abstract Studies that explore the use of lipids and their effects on animal nutrition have become increasingly abundant, producing a mass of information. The review was carried out on a parity basis through a survey of articles in the bibliographic databases: Web of Science and Periodicals Capes, using search terms associated or not, in the plural or singular, in English and Portuguese, such as: “lipids” AND “rabbits" AND "nutrition". After analyzing the files in the two scientific databases, certain files were excluded because they did not fit the theme or because they did not meet the inclusion criteria and repeated articles. A relevance test was carried out for the use of the articles, where they should deal with the subject: articles that report the use of lipids in the nutrition of non-ruminant animals; articles made available in complete form; articles that had at least one of the keywords; articles where the main subject is related to lipids. The articles were selected and tabulated in an Excel® spreadsheet with relevant information for exploration in the review. The use of oils and fats is a favorable point in the nutrition of non-ruminant animals, presenting benefits in the enrichment of final products such as: providing higher levels of omega-3 and omega-6, and thus obtaining meat products with lower levels of saturated fat and higher unsaturated fat contents promoting benefits to human health through its consumption, reduction of food costs, improvement in palatability and appearance of foods. These are nutritional strategies used in hot seasons of the year due to the low calorific increment produced. abundant databases Capes singular Portuguese as “lipids rabbits “rabbits nutrition. . "nutrition" nonruminant non ruminant animals form keywords Excel omega3 omega 3 omega- omega6, omega6 6, 6 omega-6 consumption costs foods produced "nutrition

Abstract We examine racial differentials in abortion among women in Brazil using data from three editions of the Brazilian National Abortion Survey (PNA), 2016, 2019 and 2021. We test the difference in means in data from separate surveys, combined surveys without reweighting, and combined and reweighted surveys. We also use logistic models for the chance of having an abortion. The results indicate that there is a consistent racial differential in the three editions of PNA, with the percentage of abortions among Black women being higher than among white women. In the combined and reweighted surveys, among Black women of all ages the probability of having had an abortion is 11.03% while among white women it is 7.55%. This means a difference of 3.5 percentage points, which translates into a 46% higher probability for Black women, statistically significant values for a 5% interval. Logistic regressions produce similar results, with an average predicted probability of 12.61% for Black women and 8.90% for white women, also significant. Racial differences remain statistically significant for various combinations of PNA editions. However, in the separate surveys, the difference in means tests are only statistically significant in 2016. Black refers to the group formed by Black and Brown women (pretas and pardas). Due to the small sample size, it is not possible to say much about the differences with Asian and Indigenous women.

Resumo Examinamos a realização do aborto segundo cor ou raça das mulheres no Brasil usando dados de três edições da PNA, 2016, 2019 e 2021. Comparamos diferenciais raciais aplicando testes de diferenças de médias a dados de levantamentos separados, levantamentos combinados sem reponderação, e levantamentos combinados e reponderados. Na comparação usamos ainda modelos logísticos para a chance de realização de aborto. Os resultados indicam que há diferencial racial consistente nas três edições da PNA, com os percentuais de aborto entre as mulheres negras sendo mais elevados do que entre as mulheres brancas. Nos levantamentos combinados e reponderados, entre as mulheres negras de todas as idades a probabilidade de ter feito um aborto é de 11,03% enquanto entre as mulheres brancas é de 7,55%. Isso significa uma diferença de 3,5 pontos percentuais, que se traduz em uma probabilidade 46% maior para as negras, valores estatisticamente significantes para um intervalo de 5%. Regressões logísticas produzem resultados similares, com probabilidade média predita das mulheres negras de 12,61% e das mulheres brancas de 8,90%, também significantes. As diferenças raciais persistem estatisticamente significantes para várias combinações de edições da PNA. Porém, nos levantamentos isolados os testes de diferenças de média são estatisticamente significantes apenas em 2016.

Abstract Objective The Child and Adolescent Behavior Inventory (CABI) is a cost-free 75 question-questionnaire developed by an Italian group to collect information from parents on the behavior of children and adolescents aged 6 to 18 years. It assesses different areas of children's behavior and psychopathology, including internalizing and externalizing symptoms, and can be used to identify children at risk of mental disorders both in clinical and epidemiological settings. In this study, the authors present a Brazilian-Portuguese adaptation of the CABI and its psychometric properties. Methods First, the authors conducted a rigorous transcultural adaptation of CABI's questions and instructions for the Brazilian context. In an online sample of 598 parents, the authors found high reliability (internal consistency) for the CABI's main subscales. Results Validity was supported by exploratory factor analysis (the authors found 6 factors representing several aspects of psychopathology both according to the DSM and HiTop models) and significant differences in most CABI's subscales between children with parent-reported psychopathology and typically developing ones. The present study suggests that the adapted version of CABI is a valid and reliable measure that can be used in Brazil. Conclusions The CABI can be useful to the pediatrician to get fast but wide information from parents on the behavioral condition of their children or adolescents, and also to decide whether it is appropriate to consult a mental health professional. (CABI costfree cost free 7 questionquestionnaire question questionnaire 1 years childrens s symptoms settings BrazilianPortuguese Portuguese properties First CABIs context 59 internal consistency models parentreported parent reported ones Brazil professional 5