The new digitized technologies have allowed to migrate from the technique of lost cast wax by centrifugation (CPC) to the subtractive manufacturing by CAD / CAM as the technique of soft-block milling (SMB). Objective: The purpose of this study was to compare the marginal and internal adaptations in metal Co-Cr copes on two termination lines: chamfer and bevel made by two techniques: CPC and SMB. Material and Methods: Two Co-Cr master models with chamfer and bevel termination were made, 4 study groups were formed and 13 copings were made per group. For the evaluation of the marginal and internal adaptations the replication method was used in silicone, then with a stereomicroscope the marginal and internal discrepancies were evaluated. Results: For the marginal discrepancy between the two techniques, only statistically significant differences were observed for the bevel termination (p <0.05) in points A1 and A2 and in the chamfer termination statistically significant differences were observed (p <0.05) in points A1 and F1. In the internal adaptation comparing both techniques in the bevel termination, statistically significant differences were obtained (p <0.05) in points E1, E2, D1, C2 y D2. And in the chamfer termination, the results showed statistically significant differences (p <0.05) in all the points. Conclusions: The copes that presented better marginal adaptation were those made by SMB with the chamfer termination line, in the bevel termination line it was not possible to conclude which of the two techniques is better in marginal adaptation. The ones that presented better internal adaptation in both lines of termination, in the axial zone were the copings made using the CPC technique and in the occlusal area the SMB had better internal adaptation.

Las nuevas tecnologías digitalizadas han permitido migrar de la técnica de cera perdida colada por centrifugación (CPC) a la fabricación sustractiva por CAD/CAM como la técnica de fresado de bloque blando (SMB). Objetivo: El propósito de este estudio fue comparar las adaptaciones marginales e internas en cofias metálicas de Co-Cr sobre dos líneas de terminación: chamfer y bisel confeccionadas mediante dos técnicas: CPC y SMB. Material y Métodos: Se confeccionaron dos modelos maestros de Co-Cr con terminación chamfer y bisel, se formaron 4 grupos de estudio y se fabricaron 13 cofias por grupo. Para la evaluación de las adaptaciones marginal e interna se usó el método de la réplica en silicona, luego con un estéreo microscopio se evaluó las discrepancias marginales e internas. Resultados: Para la discrepancia marginal entre las dos técnicas, para la terminación bisel sólo se observó diferencias estadísticamente significativas (p<0,05) en los puntos A1 y A2 y en la terminación chamfer se observó diferencias estadísticamente significativas (p<0,05) en los puntos A1 y F1. En la adaptación interna comparando ambas técnicas en la terminación bisel se obtuvo diferencias estadísticamente significativas (p<0,05) en los puntos E1, E2, D1, C2 y D2. En la terminación chamfer los resultados mostraron diferencias estadísticamente significativas (p<0,05) en todos los puntos. Conclusiones: Las cofias que presentaron mejor adaptación marginal fueron las confeccionadas por SMB con la línea de terminación chamfer, en la línea de terminación bisel no se pudo concluir cuál de las dos técnicas es mejor en adaptación marginal. Las que presentaron mejor adaptación interna en ambas líneas de terminación, en la zona axial fueron las cofias realizadas mediante la técnica CPC y en la zona oclusal presentaron mejor adaptación interna el SMB.

Surtos de micobactérias de crescimento rápido têm sido relatados ocasionalmente. O estudo relata um surto de abscessos cutâneos por Mycobacterium chelonae após sessões de mesoterapia em Lima, Peru. De dezembro de 2004 a janeiro de 2005, 35 pessoas que haviam passado por sessões de mesoterapia apresentaram esses abscessos cutâneos. Treze (37%) desses casos suspeitos concordaram em realizar exames clínicos. Foram realizadas biópsias de punção de pele de lesões suspeitas e examinadas substâncias injetadas durante a mesoterapia. Os casos suspeitos eram predominantemente mulheres jovens e as lesões incluíram nódulos subcutâneos, abscessos e úlceras. Mycobacterium chelonae foi isolada de quatro pacientes e de um frasco de procaína. Em conclusão, é importante considerar a mesoterapia como fonte potencial de infecções de micobactérias de crescimento rápido.

Outbreaks of rapidly growing mycobacteria have been occasionally described. The article reports an outbreak of cutaneous abscesses due to Mycobacterium chelonae following mesotherapy in Lima, Peru. From December 2004 through January 2005, 35 subjects who had participated in mesotherapy training sessions presented with persistent cutaneous abscesses. Thirteen (37%) of these suspected cases consented to underwent clinical examination. Skin punch-biopsies were collected from suspicious lesions and substances injected during mesotherapy were analyzed. Suspected cases were mainly young women and lesions included subcutaneous nodules, abscesses and ulcers. Mycobacterium chelonae was isolated from four patients and from a procaine vial. In conclusion, it is important to consider mesotherapy as a potential source of rapidly growing mycobacteria infections.

Surtos de micobactérias de crescimento rápido têm sido relatados ocasionalmente. O estudo relata um surto de abscessos cutâneos por Mycobacterium chelonae após sessões de mesoterapia em Lima, Peru. De dezembro de 2004 a janeiro de 2005, 35 pessoas que haviam passado por sessões de mesoterapia apresentaram esses abscessos cutâneos. Treze (37%) desses casos suspeitos concordaram em realizar exames clínicos. Foram realizadas biópsias de punção de pele de lesões suspeitas e examinadas substâncias injetadas durante a mesoterapia. Os casos suspeitos eram predominantemente mulheres jovens e as lesões incluíram nódulos subcutâneos, abscessos e úlceras. Mycobacterium chelonae foi isolada de quatro pacientes e de um frasco de procaína. Em conclusão, é importante considerar a mesoterapia como fonte potencial de infecções de micobactérias de crescimento rápido.

Outbreaks of rapidly growing mycobacteria have been occasionally described. The article reports an outbreak of cutaneous abscesses due to Mycobacterium chelonae following mesotherapy in Lima, Peru. From December 2004 through January 2005, 35 subjects who had participated in mesotherapy training sessions presented with persistent cutaneous abscesses. Thirteen (37%) of these suspected cases consented to underwent clinical examination. Skin punch-biopsies were collected from suspicious lesions and substances injected during mesotherapy were analyzed. Suspected cases were mainly young women and lesions included subcutaneous nodules, abscesses and ulcers. Mycobacterium chelonae was isolated from four patients and from a procaine vial. In conclusion, it is important to consider mesotherapy as a potential source of rapidly growing mycobacteria infections.

Background: Polycystic ovary syndrome (PCOS) is an endocrine metabolic dysfunction closely associated with insulin resistance and obesity, which predisposes to pregnancy complications. Aim: To report a prospective clinical experience in PCOS patients who became pregnant after diet, exercise and metformin treatment intervention, and were followed up during the whole pregnancy. Patients and Methods: Seventy pregnant PCOS (PPCOS) women and forty normal pregnant (NP) women of similar age and with singleton pregnancies were included in the study. During gestational ages 10-16 and 22-28 weeks, a 2h, 75 g oral glucose tolerance test (OGTT) was performed with measurement of glucose and insulin in each sample. Results: No differences were found in duration of gestation, weight gain during pregnancy, or systolic and diastolic blood pressure between PPCOS and NP women. There were significant differences in body mass index (BMI) at the initiation and in the third trimester of pregnancy between both groups. The incidence of gestational diabetes was significantly higher (p <0.01) in the PCOS group (35.2%) compared to the control group (5.0%). The prevalence of small for gestational age (SGA) infants tended to be higher (p =0.09) in the PCOS group. During pregnancy, 2h glucose and insulin were significantly higher in PPCOS than in NP women. Conclusions: PCOS mothers showed a higher prevalence of gestational diabetes and SGA newborns, which cannot be attributed to the weight gain during pregnancy, and seems to be more related to the BMI at the initiation of pregnancy, and to the PCOS condition of the mothe