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Factors associated with increased lactate levels in cardiac surgeries: scoping review
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Teixeira, Fernanda de Castro

; Fernandes, Thatiane Evelyn de Lima

; Leal, Karena Cristina da Silva

; Ribeiro, Katia Regina Barros

; Dantas, Daniele Vieira

; Dantas, Rodrigo Assis Neves

Revista Brasileira de Enfermagem

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2024, Volume 77 N. 1 elocation e20230117

Abstract: Es Pt En | Text: Es Pt En | PDF: Es | PDF: Pt | PDF: En

RESUMEN Objetivos: mapear los factores relacionados a la elevación del nivel de lactato en el posoperatorio de cirugía cardíaca con uso de circulación extracorporea. Métodos: se trata de una revisión de ámbito realizada en diciembre de 2022, en diez fuentes de datos. Fue elaborada conforme las recomendaciones del Instituto Joanna Briggs y del checklist Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews. Resultados: los hallados más recurrentes en los estudios sobre los factores responsables por el aumento del lactato fueron: hipoperfusión tisular, tiempo de circulación extracorporea y uso de fármacos vasoactivos. En 95% de los estudios, el aumento del lactato se relacionó al aumento de la mortalidad de los pacientes. Conclusiones: discutir sobre las causas de posibles complicaciones en pacientes de cirugía cardíaca se hace importante para el preparo del equipo y prevención de intercurrencias, además garantizar recuperación de calidad.

RESUMO Objetivos: mapear os fatores associados à elevação do nível de lactato no pós-operatório de cirurgia cardíaca com uso de circulação extracorpórea. Métodos: trata-se de uma revisão de escopo realizada em dezembro de 2022, em dez fontes de dados. Foi elaborada conforme as recomendações do Instituto Joanna Briggs e do checklist Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews. Resultados: os achados mais recorrentes nos estudos a respeito dos fatores responsáveis pelo aumento do lactato foram: hipoperfusão tecidual, tempo de circulação extracorpórea e uso de fármacos vasoativos. Em 95% dos estudos, o aumento do lactato relacionou-se ao aumento da mortalidade dos pacientes. Conclusões: discutir sobre as causas de possíveis complicações em pacientes de cirurgia cardíaca faz-se importante para o preparo da equipe e prevenção de intercorrências, além de garantir recuperação de qualidade.

ABSTRACT Objectives: to map the factors associated with increased lactate levels in the postoperative period of cardiac surgery using extracorporeal circulation. Methods: this is a scoping review carried out in December 2022, across ten data sources. It was prepared in accordance with the recommendations of the Joanna Briggs Institute and the Preferred Reporting Items for Systematic Reviews and Meta Analyses Extension for Scoping Reviews checklist. Results: the most recurrent findings in studies regarding the factors responsible for the increase in lactate were: tissue hypoperfusion, cardiopulmonary bypass time and use of vasoactive drugs. In 95% of studies, increased lactate was related to increased patient mortality. Conclusions: discussing the causes of possible complications in cardiac surgery patients is important for preparing the team and preventing complications, in addition to ensuring quality recovery.

https://doi.org/10.1590/0034-7167-2023-0117

Factors associated with increased lactate levels in cardiac surgeries: scoping review surgeries
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Teixeira, Fernanda de Castro

; Fernandes, Thatiane Evelyn de Lima

; Leal, Karena Cristina da Silva

; Ribeiro, Katia Regina Barros

; Dantas, Daniele Vieira

; Dantas, Rodrigo Assis Neves

Revista Brasileira de Enfermagem

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2024, Volume 77 N. 1 elocation e20230117

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/0034-7167-2023-0117

The QualiRede intervention: improving the performance of care continuum in HIV, congenital syphilis, and hepatitis C in health regions
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Nemes, Maria Ines Battistella

; Castanheira, Elen Rose Lodeiro Alves, Ana Maroso Adania, Carolina Simone Souza Loch, Ana Paula Monroe, Aline Aparecida Souza, Rosa Alencar Gianna, Maria Clara Caminada, Sirlene Farias, Norma Suely de Oliveira Sousa, Paula de Oliveira e Domingues, Carmen Silva Bruniera Silva, Mariliza Henrique da Cervantes, Vilma Yamashiro, Juliana Caraciolo, Joselita Maria de Magalhães Silva, Fabiano Lima da Nemes Filho, Alexandre Jesus, Gabriel Lima de Helena, Ernani Tiaraju de Santa Albiero, José Francisco Gontan Lima, Marcela Soares Silveira Bellenzani, Renata Kehrig, Ruth Terezinha Vale, Felipe Campos do Nunes, Luceime Olivia Mendonça, Carolina Siqueira Zarili, Thais Fernanda Tortorelli Vilela, Mara Cristina Dantas, Jean Carlos de Oliveira Paula, Ivone de Tayra, Ângela Coelho, Débora Moraes Santos, Glauber Palha dos Quevedo, Dulce Castro Silva, Marcia Aparecida da Silva, Iraci Batista da Nasser, Mariana Arantes Andrade, Marta Campagnoni Santos, Maria Altenfelder Mercuri, Juliana Trindade, Katia Valeska Neves, Maria Aparecida Teixeira das Toledo, Renata Villanueva Alves de Almeida, Maria Cecília Rossi de Lima, Iraty Nunes

Revista Brasileira de Epidemiologia

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2019, Volume 22 Suppl. 1 elocation e190010

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: Modelos de cuidado contínuo baseiam recentes estratégias em HIV, infecções sexualmente transmissíveis e hepatite C (HCV). Métodos: Desenvolveram-se modelos de contínuo do cuidado em HIV, HCV e sífilis congênita incluindo todas as etapas da atenção, desde a promoção e a prevenção até o controle clínico/cura. O modelo baseou a intervenção QualiRede, desenvolvida em parceria entre universidade e Sistema Único de Saúde (SUS), direcionada a gestores e demais profissionais de 6 regiões de saúde prioritárias em São Paulo e Santa Catarina. Selecionaram-se indicadores para cada etapa do contínuo do cuidado, provenientes dos sistemas de informação do SUS e dos questionários de avaliação de processo Qualiaids e QualiAB. Os indicadores formaram a base técnica de duas oficinas com profissionais e gestores de cada região: a primeira para identificar problemas e formar um Grupo Técnico Regional; e a segunda para construir planos de ação e metas a fim de melhorar o desempenho regional. Resultados: Os indicadores estão disponíveis no website www.qualirede.org. As oficinas ocorreram em quatro regiões de São Paulo (Alto Tietê, Baixada Santista, Grande ABC e Registro) e uma região de Santa Catarina (Foz do Rio Itajaí), resultando em planos regionais em São Paulo, mas não em Santa Catarina. Observou-se domínio limitado dos novos protocolos para HIV e HCV e uso incipiente de indicadores na rotina dos serviços. Conclusão: Melhorar o desempenho do contínuo do cuidado exige apropriação dos indicadores de desempenho e coordenação integrada dos fluxos de atenção em todos os níveis de gestão.

ABSTRACT Introduction: Care continuum models have supported recent strategies against sexually transmitted diseases, such as HIV and Hepatitis C (HCV). Methods: HIV, HCV, and congenital syphilis care continuum models were developed, including all stages of care, from promotion/prevention to clinical control/cure. The models supported the intervention QualiRede, developed by a University-Brazilian National Health System (SUS) partnership focused on managers and other professionals from six priority health regions in São Paulo and Santa Catarina. Indicators were selected for each stage of the care continuum from the SUS information systems and from the Qualiaids and QualiAB facility’s process evaluation questionnaires. The indicators acted as the technical basis of two workshops with professionals and managers in each region: the first one to identify problems and to create a Regional Technical Group; and the second one to design action plans for improving regional performance. Results: The indicators are available at www.qualirede.org. The workshops took place in the regions of Alto Tietê, Baixada Santista, Grande ABC, and Registro (São Paulo) and of Foz do Rio Itajaí (Santa Catarina), which resulted in regional action plans in São Paulo, but not in Santa Catarina. A lack of awareness was observed regarding the new HIV and HCV protocols, as well as an incipient use of indicators in routine practices. Conclusion: Improving the performance of the care continuum requires appropriation of performance indicators and coordination of care flows at local, regional, and state levels of management.

https://doi.org/10.1590/1980-549720190010.supl.1

The QualiRede intervention: improving the performance of care continuum in HIV, congenital syphilis, and hepatitis C in health regions
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Nemes, Maria Ines Battistella

Revista Brasileira de Epidemiologia

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2019, Volume 22 Suppl. 1 elocation e190010

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1980-549720190010.supl.1 2475 downloads

ERICA: prevalence of metabolic syndrome in Brazilian adolescents
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Kuschnir, Maria Cristina C Bloch, Katia Vergetti Szklo, Moyses Klein, Carlos Henrique Barufaldi, Laura Augusta Abreu, Gabriela de Azevedo Schaan, Beatriz Veiga, Gloria Valeria da Silva, Thiago Luiz Nogueira da Vasconcellos, Maurício T L de Moraes, Ana Júlia Pantoja de Oliveira, Ana Mayra Andrade de Tavares, Bruno Mendes Oliveira, Cecília Lacroix de Cunha, Cristiane de Freitas Giannini, Denise Tavares Belfort, Dilson Rodrigues Santos, Eduardo Lima Leon, Elisa Brosina de Oliveira, Elizabete Regina Araújo Fujimori, Elizabeth Borges, Ana Luíza Magliano, Erika da Silva Vasconcelos, Francisco de Assis Guedes Azevedo, George Dantas Brunken, Gisela Soares Guimarães, Isabel Cristina Britto Faria Neto, José Rocha Oliveira, Juliana Souza Carvalho, Kenia Mara B de Gonçalves, Luis Gonzaga de Oliveira Monteiro, Maria Inês Santos, Marize M Muniz, Pascoal Torres Jardim, Paulo César B Veiga Ferreira, Pedro Antônio Muniz Montenegro Jr, Renan Magalhães Gurgel, Ricardo Queiroz Vianna, Rodrigo Pinheiro Vasconcelos, Sandra Mary Martins, Stella Maris Seixas Goldberg, Tamara Beres Lederer

Revista de Saúde Pública

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2016, Volume 50 Suppl. 1 elocation 11s

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO OBJETIVO Determinar a prevalência de síndrome metabólica e de seus componentes em adolescentes brasileiros. MÉTODOS Foram avaliados 37.504 adolescentes, participantes do Estudo de Riscos Cardiovasculares em Adolescentes (ERICA), estudo transversal de âmbito nacional e de base escolar. Os adolescentes, de 12 a 17 anos de idade, residiam em municípios com mais de 100 mil habitantes. A amostra foi estratificada e conglomerada em escolas e turmas. Os critérios da International Diabetes Federation foram utilizados para definir síndrome metabólica. Prevalências de síndrome metabólica foram estimadas segundo sexo, faixa etária, tipo de escola e estado nutricional. RESULTADOS Dos 37.504 adolescentes, 50,2% eram do sexo feminino; 54,3% tinham de 15 a 17 anos e 73,3% estudavam em escolas públicas. A prevalência nacional de síndrome metabólica foi 2,6% (IC95% 2,3-2,9), discretamente maior no sexo masculino e naqueles de 15 a 17 anos na maioria das macrorregiões. A prevalência foi a maior nos residentes na macrorregião Sul, nas adolescentes mais jovens e nos adolescentes mais velhos. A prevalência foi maior nas escolas públicas (2,8% [IC95% 2,4-3,2]) que nas escolas privadas (1,9% [IC95% 1,4-2,4]) e nos adolescentes obesos em comparação aos não obesos. As combinações de componentes mais frequentes, respondendo por 3/4 das combinações, foram: circunferência de cintura elevada, HDL-colesterol baixo e pressão arterial elevada, seguida de circunferência da cintura elevada, lipoproteína de alta densidade (HDL-c) baixo e triglicerídeos elevados, e wpor circunferência da cintura elevada, HDL baixa e triacilgliceróis e pressão arterial elevados. A HDL baixa foi o segundo componente mais frequente, mas a maior prevalência de síndrome metabólica (26,8%) foi observada na presença de triglicerídeos elevado. CONCLUSÕES O ERICA é o primeiro estudo nacional a apresentar prevalências de síndrome metabólica e descrever a participação dos seus componentes. Apesar de a prevalência da síndrome metabólica ter sido baixa, as altas prevalências de alguns componentes e de participação de outros na composição da síndrome torna importante o diagnóstico precoce de tais alterações, mesmo que não agrupadas na síndrome metabólica.

ABSTRACT OBJECTIVE To determine the prevalence of metabolic syndrome and its components in Brazilian adolescents. METHODS We evaluated 37,504 adolescents who were participants in the Study of Cardiovascular Risks in Adolescents (ERICA), a cross-sectional, school-based, national study. The adolescents, aged from 12 to 17 years, lived in cities with populations greater than 100,000 inhabitants. The sample was stratified and clustered into schools and classes. The criteria set out by the International Diabetes Federation were used to define metabolic syndrome. Prevalences of metabolic syndrome were estimated according to sex, age group, school type and nutritional status. RESULTS Of the 37,504 adolescents who were evaluated: 50.2% were female; 54.3% were aged from 15 to 17 years, and 73.3% were from public schools. The prevalence of metabolic syndrome was 2.6% (95%CI 2.3-2.9), slightly higher in males and in those aged from 15 to 17 years in most macro-regions. The prevalence was the highest in residents from the South macro-region, in the younger female adolescents and in the older male adolescents. The prevalence was higher in public schools (2.8% [95%CI 2.4-3.2]), when compared with private schools (1.9% [95%CI 1.4-2.4]) and higher in obese adolescents when compared with nonobese ones. The most common combinations of components, referring to 3/4 of combinations, were: enlarged waist circumference (WC), low HDL-cholesterol (HDL-c) and high blood pressure; followed by enlarged WC, low HDL-c and high triglycerides; and enlarged WC, low HDL-c, high triglycerides and blood pressure. Low HDL was the second most frequent component, but the highest prevalence of metabolic syndrome (26.8%) was observed in the presence of high triglycerides. CONCLUSIONS ERICA is the first Brazilian nation-wide study to present the prevalence of metabolic syndrome and describe the role of its components. Despite the prevalence of Metabolic Syndrome being low, the high prevalences of some components and participation of others in the syndrome composition shows the importance of early diagnosis of this changes, even if not grouped within the metabolic syndrome.

https://doi.org/10.1590/s01518-8787.2016050006701 1789 downloads

ERICA: prevalences of hypertension and obesity in Brazilian adolescents
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Bloch, Katia Vergetti Klein, Carlos Henrique Szklo, Moyses Kuschnir, Maria Cristina C Abreu, Gabriela de Azevedo Barufaldi, Laura Augusta Veiga, Gloria Valeria da Schaan, Beatriz Silva, Thiago Luiz Nogueira da Moraes, Ana Julia Pantoja Oliveira, Ana Mayra Andrade de Tavares, Bruno Mendes Magliano, Erika da Silva Oliveira, Cecília Lacroix de Cunha, Cristiane de Freitas Giannini, Denise Tavares Belfort, Dilson Rodrigues Santos, Eduardo Lima Leon, Elisa Brosina de Oliveira, Elizabete Regina Araújo Fujimori, Elizabeth Borges, Ana Luíza Vasconcelos, Francisco de Assis Guedes Azevedo, George Dantas Brunken, Gisela Soares Guimarães, Isabel Cristina Britto Faria Neto, José Rocha Oliveira, Juliana Souza Carvalho, Kenia Mara B. de Gonçalves, Luis Gonzaga de Oliveira Monteiro, Maria Inês Santos, Marize M. Jardim, Paulo César B. Veiga Ferreira, Pedro Antônio Muniz Montenegro Jr., Renan Magalhães Gurgel, Ricardo Queiroz Vianna, Rodrigo Pinheiro Vasconcelos, Sandra Mary Goldberg, Tamara Beres Lederer

Revista de Saúde Pública

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2016, Volume 50 Suppl. 1 elocation 9s

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO OBJETIVO Estimar as prevalências de hipertensão arterial e obesidade e a fração atribuível populacional de hipertensão arterial devida à obesidade em adolescentes brasileiros. MÉTODOS Foram avaliados dados dos participantes do Estudo de Riscos Cardiovasculares em Adolescentes, estudo seccional l nacional de base escolar. A amostra foi dividida em 32 estratos geográficos e conglomerados de escolas e turmas, com representatividade nacional, macrorregional e de capitais. Obesidade foi classificada pelo índice de massa corporal segundo idade e sexo. Considerou-se hipertensão arterial a média da pressão arterial sistólica ou diastólica maior ou igual ao percentil 95 da curva de referência. Foram estimadas prevalências e intervalos de confiança de 95% (IC95%) de hipertensão arterial e de obesidade, nacionais e nas macrorregiões do País, por sexo e grupo etário, assim como as frações de hipertensão atribuíveis à obesidade na população. RESULTADOS Foram avaliados 73.399 estudantes, 55,4% do sexo feminino, com média de idade 14,7 anos (DP = 1,6). A prevalência de hipertensão arterial foi 9,6% (IC95% 9,0-10,3); sendo as mais baixas observadas nas regiões Norte, 8,4% (IC95% 7,7-9,2) e Nordeste, 8,4% (IC95% 7,6-9,2) e a mais alta na região Sul, 12,5% (IC95% 11,0-14,2). A prevalência de obesidade foi 8,4% (IC95% 7,9-8,9), mais baixa na região Norte e mais alta na Sul. As prevalências de hipertensão arterial e obesidade foram maiores no sexo masculino. Adolescentes com obesidade tiveram prevalência de hipertensão arterial mais elevada, 28,4% (IC95% 25,5-31,2), do que aqueles com sobrepeso, 15,4% (IC95% 13,8-17,0), ou eutróficos, 6,3% (IC95% 5,6-7,0). A fração de hipertensão arterial atribuível à obesidade foi de 17,8%. CONCLUSÕES O ERICA foi o primeiro estudo brasileiro com representatividade nacional a estimar a prevalência de hipertensão arterial aferida em adolescentes. A fração da prevalência de hipertensão arterial atribuível à obesidade mostrou que cerca de 1/5 dos hipertensos poderiam não ser hipertensos se não fossem obesos.

ABSTRACT OBJECTIVE To estimate the prevalence of arterial hypertension and obesity and the population attributable fraction of hypertension that is due to obesity in Brazilian adolescents. METHODS Data from participants in the Brazilian Study of Cardiovascular Risks in Adolescents (ERICA), which was the first national school-based, cross-section study performed in Brazil were evaluated. The sample was divided into 32 geographical strata and clusters from 32 schools and classes, with regional and national representation. Obesity was classified using the body mass index according to age and sex. Arterial hypertension was defined when the average systolic or diastolic blood pressure was greater than or equal to the 95th percentile of the reference curve. Prevalences and 95% confidence intervals (95%CI) of arterial hypertension and obesity, both on a national basis and in the macro-regions of Brazil, were estimated by sex and age group, as were the fractions of hypertension attributable to obesity in the population. RESULTS We evaluated 73,399 students, 55.4% female, with an average age of 14.7 years (SD = 1.6). The prevalence of hypertension was 9.6% (95%CI 9.0-10.3); with the lowest being in the North, 8.4% (95%CI 7.7-9.2) and Northeast regions, 8.4% (95%CI 7.6-9.2), and the highest being in the South, 12.5% (95%CI 11.0-14.2). The prevalence of obesity was 8.4% (95%CI 7.9-8.9), which was lower in the North region and higher in the South region. The prevalences of arterial hypertension and obesity were higher in males. Obese adolescents presented a higher prevalence of hypertension, 28.4% (95%CI 25.5-31.2), than overweight adolescents, 15.4% (95%CI 17.0-13.8), or eutrophic adolescents, 6.3% (95%CI 5.6-7.0). The fraction of hypertension attributable to obesity was 17.8%. CONCLUSIONS ERICA was the first nationally representative Brazilian study providing prevalence estimates of hypertension in adolescents. Regional and sex differences were observed. The study indicates that the control of obesity would lower the prevalence of hypertension among Brazilian adolescents by 1/5.

https://doi.org/10.1590/s01518-8787.2016050006685 1511 downloads

ERICA: prevalences of hypertension and obesity in Brazilian adolescents
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Revista de Saúde Pública

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2016, Volume 50 Suppl. 1 elocation 9s

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/s01518-8787.2016050006685 18629 downloads

ERICA: prevalence of metabolic syndrome in Brazilian adolescents
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Revista de Saúde Pública

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2016, Volume 50 Suppl. 1 elocation 11s

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/s01518-8787.2016050006701 11875 downloads

Efeito da cinesioterapia na qualidade de vida, função sexual e sintomas climatéricos em mulheres com fibromialgia
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Lisboa, Lilian Lira Sonehara, Elisa Oliveira, Katia Cristina Araújo Nogueira de Andrade, Sandra Cristina de Azevedo, George Dantas

Revista Brasileira de Reumatologia

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jun 2015, Volume 55 N. 3 Pages 209 - 215

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Objetivo: Avaliar e comparar o efeito da cinesioterapia na qualidade de vida, função sexual e sintomas climatéricos em mulheres climatéricas com e sem fibromialgia. Métodos: Participaram 90 mulheres climatéricas, divididas em dois grupos: fibromialgia (47) e controle (43). As pacientes foram avaliadas nas variáveis: qualidade de vida (Utian Quality of Life [UQOL]), função sexual (questionário do quociente sexual/versão feminina [QS-F]) e intensidade dos sintomas climatérios (Índice Menopausal de Blatt-Kupperman [IMBK]). Os grupos fizeram cinesioterapia para o assoalho pélvico, composto de 20 sessões, duas vezes por semana. Análise estatística foi feita por meio dos testes t de Student pareado, análise de variância de delineamento misto e Kappa de Cohen. Resultados: Na qualidade de vida, foi observada melhoria em ambos os grupos para todos os domínios avaliados. Na análise intergrupo foi evidenciada diferença nos domínios emocional (p = 0,01), saúde (0,03) e sexual (p = 0,001) com ganhos mais expressivos para o grupo controle. Na função sexual, foi verificada melhoria nos grupos, após a intervenção; na análise intergrupo as fibromiálgicas apresentaram escores inferiores ao grupo controle (p < 0,001). Em relação aos sintomas climatéricos não houve diferença na análise intergrupo pós-intervenção (p = 0,73). Entretanto, ambos os grupos apresentaram redução significativa da sintomatologia após a intervenção (p < 0,001). Conclusões: A cinesioterapia do assoalho pélvico exerce efeito benéfico sobre os domínios da qualidade de vida, função sexual e sintomatologia climatérica em mulheres com e sem fibromialgia na fase do climatério. Entretanto, a fibromialgia parece ser fator limitante para melhores resultados em alguns aspectos avaliados

Objective: To evaluate the effect of the kinesiotherapy in the quality of life, sexual function and menopause-related symptoms and compare in climacteric women with and without fibromyalgia (FM). Methodology: The group was composed of 90 climacteric women divided in 2 groups: FM (47) and control (43). The patients were analyzed on their quality of life (Utian Quality of Life [UQoL]), sexual function (Sexual Quotient-Female Version [SQ-F] questionnaire) and intensity of the climacteric symptoms (Blatt–Kupperman menopausal index [BKMI]). Both groups performed pelvic floor kinesiotherapy, composed of 20 sessions, twice a week. Statistical analysis was performed using Student's t-test, mixed-design analysis of variance (ANOVA) and Cohen's Kappa. Results: In the quality of life, an improvement was noticed in both groups for all domains analyzed. In the comparison between groups it was noticed a difference in the emotional (p = 0.01), health (p = 0.03) and sexual (p = 0.001) domains with considerable gains verified in the control group. Improvement was also noticed in the sexual function. In the analysis between groups, FM group showed a lower score compared to the control group (p < 0.001). With respect to the climacteric symptoms, there was no difference in the analysis between groups after the intervention (p < 0.001). Conclusions: The pelvic floor kinesiotherapy promotes a positive effect in the domains of quality of life, sexual function and climacteric symptoms in women with and without fibromyalgia in the climacteric period; however, fibromyalgia seems to be a limiting factor to achieve better results in some of the aspects evaluated.

https://doi.org/10.1016/j.rbr.2014.08.019 8920 downloads

10.

Effects of calcium hydroxide addition on the physical and chemical properties of a calcium silicate-based sealer
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KUGA, Milton Carlos DUARTE, Marco Antonio Hungaro SANT'ANNA-JÚNIOR, Arnaldo KEINE, Kátia Cristina FARIA, Gisele DANTAS, Andrea Abi Rached GUIOTTI, Flávia Angélica

Journal of Applied Oral Science

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jun 2014, Volume 22 N. 3 Pages 180 - 184

Abstract: En | Text: En | PDF: En

Recently, various calcium silicate-based sealers have been introduced for use in root canal filling. The MTA Fillapex is one of these sealers, but some of its physicochemical properties are not in accordance with the ISO requirements. Objective: The aim of this study was to evaluate the flowability, pH level and calcium release of pure MTA Fillapex (MTAF) or containing 5% (MTAF5) or 10% (MTAF10) calcium hydroxide (CH), in weight, in comparison with AH Plus sealer. Material and Methods: The flowability test was performed according to the ISO 6876:2001 requirements. For the pH level and calcium ion release analyses, the sealers were placed individually (n=10) in plastic tubes and immersed in deionized water. After 24 hours, 7 and 14 days, the water in which each specimen had been immersed was evaluated to determine the pH level changes and calcium released. Flowability, pH level and calcium release data were analyzed statistically by the ANOVA test (α=5%). Results: In relation to flowability: MTAF>AH Plus>MTAF5>MTAF10. In relation to the pH level, for 24 h: MTAF5=MTAF10=MTAF>AH Plus; for 7 and 14 days: MTAF5=MTAF10>MTAF>AH Plus. For the calcium release, for all periods: MTAF>MTAF5=MTAF10>AH Plus. Conclusions: The addition of 5% CH to the MTA Fillapex (in weight) is an alternative to reduce the high flowability presented by the sealer, without interfering in its alkalization potential.

https://doi.org/10.1590/1678-775720130032 2078 downloads

11.

Importance of the association of molecular and immunological diagnosis in immunocompetent patient with Histoplasma capsulatum and Cryptoccocus neoformans infection: a case report
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Dantas, Kátia Cristina Freitas, Roseli Santos de Garcia, Roberta Scholz Pinto Silva, Marcos Vinícius da Muricy, Edna Cleide Mendes Kohara, Valdelene Sayuri Vicentini, Adriana Pardini

Journal of Venomous Animals and Toxins including Tropical Diseases

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2014, Volume 20 elocation 36

Abstract: En | Text: En | PDF: En

This case reports an immunocompetent 29-year-old woman with suspected pneumonia, suggestive of fungal infection. Immunoblotting analysis reactivity againstHistoplasma capsulatum and Paracoccidioides brasiliensis were observed. Nested-PCR in blood employing species-specific primers was positive for H. capsulatum andCryptococcus neoformans. The evaluation of paucisymptomatic patients with positive results for H. capsulatum and C. neoformans could be relevant for the prevention as well as the possible evaluation of the reactivated quiescent foci. In conclusion, the associated methodology may have contributed to the monitoring endogenous reactivation of these diseases.

https://doi.org/10.1186/1678-9199-20-36 1014 downloads

12.

The use of nested Polymerase Chain Reaction (nested PCR) for the early diagnosis of Histoplasma capsulatum infection in serum and whole blood of HIV-positive patients*
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Dantas, Katia Cristina Freitas, Roseli S. Moreira, Adriana Pardini Vicentini Silva, Marcos Vinicius da Benard, Gil Vasconcellos, Cidia Criado, Paulo Ricardo

Anais Brasileiros de Dermatologia

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feb 2013, Volume 88 N. 1 Pages 141 - 143

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O objetivo do estudo consistiu em detectar seqüências no ADNr e as suas regiões no Histoplasma capsulatum, que pudessem ser consideradas espécie-específicas e usadas como método molecular para o diagnóstico pela técnica da reação em cadeia da polimerase aninhada ("nested PCR") com seqüências específicas ("primers") para H. capsulatum: regiões 18S ADNr (HC18), 100kDa (HC100) e a seqüência 5.8 S ADNr-ITS (HC5.8). A "nested PCR" com as seqüências HC18, HC100 e HC5.8 resultaram em 100% de especificidade. Os ensaios moleculares podem aumentar a especificidade, sensibilidade e rapidez na diagnose da Histoplasmose.

The aim of the study was to detect the rDNA sequences and their regions in Histoplasma capsulatum, which could be considered species-specific and used as a molecular method for this diagnosis by the technique of nested polymerase chain reaction (nested PCR), employing specific sequences (primers) for H. capsulatum: 18S rDNA region (HC18), 100 kDa (HC100) and the sequence 5.8 S-ITS rDNA (HC5.8). The PCR sequences HC18, HC100 and HC5.8 resulted in a specificity of 100%. The molecular assays may increase the specificity, sensitivity and speed in the diagnosis of Histoplasmosis.

https://doi.org/10.1590/S0365-05962013000100025 3335 downloads Cited 1 time in SciELO

13.

Micoses superficiais e os elementos da resposta imune
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Criado, Paulo Ricardo Oliveira, Cristiane Beatriz de Dantas, Kátia Cristina Takiguti, Filomena Amaro Benini, Luciana Vasconcellos Vasconcellos, Cidia

Anais Brasileiros de Dermatologia

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aug 2011, Volume 86 N. 4 Pages 726 - 731

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

As micoses superficiais são prevalentes em todo o mundo, geralmente ocasionadas por dermatófitos e restritas à camada córnea. A resposta imunológica do hospedeiro às infecções dos fungos dermatófitos depende basicamente das defesas do hospedeiro a metabólitos do fungo, da virulência da cepa ou da espécie infectante e da localização anatômica da infecção. Serão revistos alguns dos fatores da defesa imunológica do hospedeiro que influenciam na eficácia da resposta imune. Em especial, a participação dos receptores de padrão de reconhecimento (PRRs), tais como os receptores toll-like ou os da família lectina (DC-SIGN e dectin-2), que participam da resposta imune inata, conferindo-lhe especificidade e definindo o padrão da resposta imune como um todo. O predomínio celular ou humoral da resposta imune definirá o quadro clínico e o prognóstico da infecção, levando à cura ou cronicidade

Superficial mycoses are prevalent worldwide. They are often caused by dermatophytes and restricted to the stratum corneum. The host's immune response against infections caused by dermatophytes basically depends on the host's defense against metabolites of the fungi, virulence of the infecting strain or species and anatomical site of the infection. We will review some of the factors of the host's immune defense that influence the efficacy of the immune response. We will particularly review the role of pattern recognition receptors (PRRs), such as toll-like receptors or lectin receptors (DCSIGN and Dectin 2), which participate in the innate immune response, bringing specificity to the immune response and setting its pattern. The predominance of a cellular or humoral immune response determines the clinical manifestations and the prognosis of the infection, leading to healing or chronicity

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14.

A multicenter feasibility study of chronic graft-versus-host disease according to the National Institute of Health criteria: efforts to establish a Brazil-Seattle consortium as a platform for future collaboration in clinical trials
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Vigorito, Afonso Celso Bouzas, Luis Fernando da Silva Moreira, Maria Cláudia Rodrigues Funke, Vaneuza Araújo Moreira Colturato, Virgílio Antonio Rensi Pedro, Andréia Souza, Clarissa Vasconcellos de Nunes, Elenaide Coutinho Miranda, Eliana Cristina Martins Camacho, Kátia Mauad, Marcos Augusto Correa, Maria Elvira Pizzigatti Silva, Márcia de Matos Sousa, Mair Pedro de Tavares, Rita de Cássia Barbosa da Silva Lee, Stephanie Joi Flowers, Mary Evelyn Dantas

Revista Brasileira de Hematologia e Hemoterapia

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2011, Volume 33 N. 4 Pages 283 - 289

Abstract: En | Text: En | PDF: En

BACKGROUND: New criteria for the diagnosis and classification of chronic graft-versus-host disease were developed in 2005 for the purpose of clinical trials with a consensus sponsored by the National Institute of Health. OBJECTIVES: The aim of this study is to present the results of a multicenter pilot study performed by the Brazil-Seattle chronic graft-versus-host disease consortium to determine the feasibility of using these criteria in five Brazilian centers. METHODS: The study was performed after translation of the consensus criteria into Portuguese and training. A total of 34 patients with National Institute of Health chronic graft-versus-host disease were enrolled in the pilot study between June 2006 and May 2009. RESULTS: Of the 34 patients, 26 (76%) met the criteria of overlap syndrome and eight (24%) the classic subcategory. The overall severity of disease was moderate in 21 (62%) and severe in 13 (38%) patients. The median time from transplant to onset of chronic graft-versus-host disease was 5.9 months (Range: 3 - 16 months); the median time for the overlap syndrome subcategory was 5.9 months (Range: 3 - 10 months) and for the classic subcategory, it was 7.3 months (Range: 3 - 16 months). At a median follow up of 16.5 months (Range: 4 - 39 months), overall survival was 75%. CONCLUSIONS: It was feasible to use the National Institute of Health consensus criteria for the diagnosis and scoring of chronic graft-versus-host disease in a Brazilian prospective multicenter study. More importantly, a collaborative hematopoietic cell transplantation network was established in Brazil offering new opportunities for future clinical trials in chronic graft-versus-host disease and in other areas of research involving hematopoietic stem cell transplantation.

https://doi.org/10.5581/1516-8484.20110078 2365 downloads

15.

Contribuição da educação popular no atendimento fisioterapêutico domiciliar
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Torres, Cristina Katya Dantas Estrela, Joseane de Fátima Madruga Ribeiro, Kátia Suely Queiroz Silva

Ciência & Saúde Coletiva

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dec 2009, Volume 14 N. 5 Pages 1877 - 1879

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O projeto de extensão Fisioterapia na Comunidade é desenvolvido no Bairro do Grotão, vinculado às unidades de saúde da família, em João Pessoa. Procura-se neste trabalho valorizar os saberes e práticas populares. A assistência fisioterapêutica domiciliar à luz da educação popular, ao mesmo tempo em que promove uma assistência à população desassistida, amplia nossa visão de saúde como processo educativo. A cada visita domiciliar, nos confrontamos com a realidade social das camadas populares e os problemas que estas pessoas enfrentam, repercutindo no seu estado de saúde, evidenciando para nós os condicionantes socioeconômicos do processo saúde-doença. Observa-se que, ao realizar atendimentos domiciliares com base nos princípios da educação popular, amplia-se a perspectiva de atuação do fisioterapeuta. Isso se deve ao fato de ser esta uma educação baseada no diálogo, que propõe a troca entre os saberes científico e popular, motivando a perspectiva de um compromisso à saúde junto à comunidade.

The extension project of Physiotherapy in the Community is developed in the neighborhood of Grotão linked to the family health units, in the city of João Pessoa. The aim of this work is to value popular knowledge and practices. The domiciliary physiotherapeutical assistance to the light of the popular education, at the same time that it promotes assistance to the unassisted population, extends our vision of health as an educational process. In each domiciliary visit we observed the social reality of the popular layers and the problems these people face, reflecting in its state of health, being evident for us the partner-economic conditionants of the process health-illness. This is observed that when carrying out domiciliary consultation on the basis of the principles of the popular education, it extents the perspective of the performance of the physiotherapist. This is so, because it is an education based on the dialogue, that proposes the exchange between scientific and popular knowledge, motivating the perspective of a commitment to the health together with the community.

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